Search of human proteins with 170295807

Search of human proteins with 170295807

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170295807 neuroserpin precursor [Homo sapiens]
         (410 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170295807 neuroserpin precursor [Homo sapiens]                     807   0.0  
gi|4826904 neuroserpin precursor [Homo sapiens]                       807   0.0  
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   316   2e-86
gi|211904156 plasminogen activator inhibitor type 1, member 2 is...   238   1e-62
gi|211904154 plasminogen activator inhibitor type 1, member 2 is...   238   1e-62
gi|211904152 plasminogen activator inhibitor type 1, member 2 is...   238   1e-62
gi|24307907 plasminogen activator inhibitor type 1, member 2 iso...   234   8e-62
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]          229   3e-60
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   223   2e-58
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   223   2e-58
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   219   5e-57
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   218   8e-57
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   218   8e-57
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   217   2e-56
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   213   2e-55
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   212   4e-55
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   198   8e-51
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   195   5e-50
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   195   5e-50
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...   193   2e-49
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   193   2e-49
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (...   188   7e-48
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o...   188   7e-48
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   188   7e-48
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   187   2e-47
gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]   180   2e-45
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   179   5e-45
gi|73858566 heparin cofactor II precursor [Homo sapiens]              177   1e-44
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   177   2e-44
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   177   2e-44

>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  807 bits (2085), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMM 60
           MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMM
Sbjct: 1   MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMM 60

Query: 61  ELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHV 120
           ELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHV
Sbjct: 61  ELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHV 120

Query: 121 NEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLAL 180
           NEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLAL
Sbjct: 121 NEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLAL 180

Query: 181 INAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQ 240
           INAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQ
Sbjct: 181 INAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQ 240

Query: 241 VLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQE 300
           VLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQE
Sbjct: 241 VLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQE 300

Query: 301 IDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI 360
           IDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI
Sbjct: 301 IDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI 360

Query: 361 SRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 410
           SRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL
Sbjct: 361 SRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 410


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  807 bits (2085), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMM 60
           MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMM
Sbjct: 1   MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMM 60

Query: 61  ELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHV 120
           ELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHV
Sbjct: 61  ELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHV 120

Query: 121 NEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLAL 180
           NEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLAL
Sbjct: 121 NEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLAL 180

Query: 181 INAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQ 240
           INAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQ
Sbjct: 181 INAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQ 240

Query: 241 VLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQE 300
           VLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQE
Sbjct: 241 VLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQE 300

Query: 301 IDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI 360
           IDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI
Sbjct: 301 IDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI 360

Query: 361 SRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 410
           SRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL
Sbjct: 361 SRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 410


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  316 bits (810), Expect = 2e-86
 Identities = 159/405 (39%), Positives = 258/405 (63%), Gaps = 5/405 (1%)

Query: 6   LFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQ 65
           L+SLL+L   +  +    +   + +V++Y  +  + +D NI+FSPL I L + M++LGA+
Sbjct: 6   LWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAK 64

Query: 66  GSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFL 125
           G  Q++IR ++       GEEF  LK F + ++ K+ ++   +AN+L++Q GF V E++L
Sbjct: 65  GKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYL 124

Query: 126 QMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVY 185
              K++F +A+  VDF    A A  I+ WVE  T+  +KD+ S  +F   T L L+NA+Y
Sbjct: 125 HGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIY 184

Query: 186 FKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIP 245
           FKG+WK +FR E+T+  +FTK + S V+IPMM       YG FS+ S      YQVLE+ 
Sbjct: 185 FKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLN----YQVLELS 240

Query: 246 YEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKD 305
           Y+GDE S++++L  + + +  +E L+ AQ + +W + +++++VE+ LPRF VEQ++D KD
Sbjct: 241 YKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKD 300

Query: 306 VLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV 365
           VL +L ITEIF    +L+G++D+ E+++S+   K F E+NE+GSEAA  +G+     M++
Sbjct: 301 VLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSL 360

Query: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 410
              Q I +HPF F++++  T +ILFMGRV +P+T    G D + L
Sbjct: 361 AQSQFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDLDSL 405


>gi|211904156 plasminogen activator inhibitor type 1, member 2
           isoform c precursor [Homo sapiens]
          Length = 409

 Score =  238 bits (606), Expect = 1e-62
 Identities = 130/378 (34%), Positives = 223/378 (58%), Gaps = 11/378 (2%)

Query: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 40  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 99

Query: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 100 VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 156

Query: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 157 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 216

Query: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 217 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 273

Query: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 274 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 333

Query: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379
           AN   ++ ++ + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F 
Sbjct: 334 ANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLFF 391

Query: 380 IRNRRTGTILFMGRVMHP 397
           IR+  TG +LFMG++  P
Sbjct: 392 IRHNPTGAVLFMGQINKP 409


>gi|211904154 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  238 bits (606), Expect = 1e-62
 Identities = 130/378 (34%), Positives = 223/378 (58%), Gaps = 11/378 (2%)

Query: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 28  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 87

Query: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 88  VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144

Query: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 204

Query: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 205 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 261

Query: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321

Query: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379
           AN   ++ ++ + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F 
Sbjct: 322 ANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLFF 379

Query: 380 IRNRRTGTILFMGRVMHP 397
           IR+  TG +LFMG++  P
Sbjct: 380 IRHNPTGAVLFMGQINKP 397


>gi|211904152 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  238 bits (606), Expect = 1e-62
 Identities = 130/378 (34%), Positives = 223/378 (58%), Gaps = 11/378 (2%)

Query: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 28  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 87

Query: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 88  VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144

Query: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 204

Query: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 205 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 261

Query: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321

Query: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379
           AN   ++ ++ + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F 
Sbjct: 322 ANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLFF 379

Query: 380 IRNRRTGTILFMGRVMHP 397
           IR+  TG +LFMG++  P
Sbjct: 380 IRHNPTGAVLFMGQINKP 397


>gi|24307907 plasminogen activator inhibitor type 1, member 2
           isoform a precursor [Homo sapiens]
          Length = 398

 Score =  234 bits (598), Expect = 8e-62
 Identities = 131/379 (34%), Positives = 222/379 (58%), Gaps = 12/379 (3%)

Query: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 28  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 87

Query: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 88  VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144

Query: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 204

Query: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 205 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 261

Query: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321

Query: 320 ANLTGLSDNKE-IFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFF 378
           AN   ++   E + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F
Sbjct: 322 ANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLF 379

Query: 379 LIRNRRTGTILFMGRVMHP 397
            IR+  TG +LFMG++  P
Sbjct: 380 FIRHNPTGAVLFMGQINKP 398


>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
          Length = 402

 Score =  229 bits (584), Expect = 3e-60
 Identities = 124/373 (33%), Positives = 214/373 (57%), Gaps = 8/373 (2%)

Query: 27  ADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEE 86
           +D  V ++ ++    +D N++FSP  +A  + M++L   G TQ++I+ +MG+     G  
Sbjct: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMA 95

Query: 87  FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVA 146
            + L+     +    ++  +   +++FVQ    + + F+    + F + V  VDFS+   
Sbjct: 96  PA-LRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVER 154

Query: 147 VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTK 206
               IN WV+ +T  ++ +L+     D  T L L+NA+YF G WK+ F   +T    F K
Sbjct: 155 ARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHK 214

Query: 207 DDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS-RQEVPLA 265
            D S V +PMM Q  +F Y EF   +   G  Y +LE+PY GD +SM +     +EVPL+
Sbjct: 215 SDGSTVSVPMMAQTNKFNYTEF---TTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLS 271

Query: 266 TLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-DANLTG 324
            L  ++ AQL+  W  ++ +    + LP+F++E E+DL+  L+ LG+T++F +  A+ T 
Sbjct: 272 ALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTS 331

Query: 325 LSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRR 384
           LSD + + +++A+ K  +EVNE G+ A++ + +I  +RMA    ++I+D PF F++R+  
Sbjct: 332 LSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAP--EEIIMDRPFLFVVRHNP 389

Query: 385 TGTILFMGRVMHP 397
           TGT+LFMG+VM P
Sbjct: 390 TGTVLFMGQVMEP 402


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  223 bits (569), Expect = 2e-58
 Identities = 134/377 (35%), Positives = 217/377 (57%), Gaps = 28/377 (7%)

Query: 35  NRLRATGED--ENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKE 92
           N L+  G+D  +N+ FSP+S++ A+ M+ +GA+G+T  ++   + ++  K+G      + 
Sbjct: 14  NLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN--KSGGGGDIHQG 71

Query: 93  FSNMVTAKE---SQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVAN 149
           F +++T      +QY++++AN LF +        F    +K++ A +  +DF   V  + 
Sbjct: 72  FQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSR 131

Query: 150 -YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENT--RTFSFTK 206
            +IN WV   T   + +L+SP   D  T L L+NAVYF+GNW  QF  ENT  R F  +K
Sbjct: 132 KHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSK 191

Query: 207 DDESEVQIPMMYQQGEF---YYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263
           ++E  VQ  MM++Q  F   Y GE            Q+L +PY G E++M+++L  +   
Sbjct: 192 NEEKPVQ--MMFKQSTFKKTYIGEI---------FTQILVLPYVGKELNMIIMLPDETTD 240

Query: 264 LATLEPLVKAQLVEEWA--NSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKDA 320
           L T+E  +  +   EW   + + +++VEV LPRF +E+  D++ VL+ LG+T+ F +  A
Sbjct: 241 LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKA 300

Query: 321 NLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLI 380
           + +G+S   ++ LSK +HKSF+EVNEEG+EAAA +  I + R A   P+   DHPF F I
Sbjct: 301 DFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFI 359

Query: 381 RNRRTGTILFMGRVMHP 397
           ++ +T  ILF GR   P
Sbjct: 360 QHSKTNGILFCGRFSSP 376


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  223 bits (568), Expect = 2e-58
 Identities = 127/392 (32%), Positives = 219/392 (55%), Gaps = 25/392 (6%)

Query: 24  EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-- 81
           EA      +++ + R + E+ NI +SP+SI  A+GM+ LGA+ +T ++I+  + +D +  
Sbjct: 6   EANTKFMFDLFQQFRKSKEN-NIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTE 64

Query: 82  ------------KNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMK 129
                       ++G      ++           Y +KIAN LF +  +   +E+L  +K
Sbjct: 65  NTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIK 124

Query: 130 KYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKG 188
           K++  +V  VDF+     +   IN WVE+ TN  +K+L+   +  + T L L+NA+YFKG
Sbjct: 125 KFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKG 184

Query: 189 NWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEG 248
            W+ +F  E+T+   F  +  +   I MM Q   F++    D   +      VLEIPY+G
Sbjct: 185 QWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAK------VLEIPYKG 238

Query: 249 DEISMMLVLSRQEVPLATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDV 306
            ++SM+++L  +   L  LE  + A+ + EW +  ++++ +V+++LPRF VE+  DLKD 
Sbjct: 239 KDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDT 298

Query: 307 LKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI-SRMAV 365
           L+ +G+ +IF  DA+L+G++ ++ + LS  +HK+F+EV EEG+EAAA + ++   S    
Sbjct: 299 LRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTS 358

Query: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
              +   +HPF F IR  +T +ILF GR   P
Sbjct: 359 TNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  219 bits (557), Expect = 5e-57
 Identities = 132/393 (33%), Positives = 217/393 (55%), Gaps = 27/393 (6%)

Query: 25  AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGY----DS 80
           A  +  ++++  L +    +NI FS LS+  A+ M+ LGA+G T++++   + +    DS
Sbjct: 7   ANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDS 66

Query: 81  LKNGEEFS------------FLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMM 128
           LK G + S            F  EFS  +   +S   + IAN L+       ++++L   
Sbjct: 67  LKPGFKDSPKCSQAGRIHSEFGVEFSQ-INQPDSNCTLSIANRLYGTKTMAFHQQYLSCS 125

Query: 129 KKYFNAAVNHVDFSQNVA-VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFK 187
           +K++ A +  VDF Q+       IN WVEN TN  V +L      D ++ + L+NA+YFK
Sbjct: 126 EKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFK 185

Query: 188 GNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYE 247
           G W+++F+   T    F   +   V + MMYQ G F      +         QVLE+PY 
Sbjct: 186 GQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQ------MQVLELPYV 239

Query: 248 GDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANS--VKKQKVEVYLPRFTVEQEIDLKD 305
            +++SM+++L      L  +E  + +    EW +S  + +++VEV+LPRF +E + +L  
Sbjct: 240 NNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNS 299

Query: 306 VLKALGITEIFIK-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMA 364
           +LK+LG+T++F +  A+L+G+S  K ++LSKAIHKS+L+V+EEG+EAAA +G     +  
Sbjct: 300 LLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSL 359

Query: 365 VLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
            +  Q   +HPF F IR+  T TILF G++  P
Sbjct: 360 PMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  218 bits (555), Expect = 8e-57
 Identities = 125/378 (33%), Positives = 211/378 (55%), Gaps = 13/378 (3%)

Query: 24  EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83
           EA    +++++  L       N+ FSP+SI+ A+ M+ +GA+GST  ++  ++     K+
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--YKD 63

Query: 84  GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
           G+     +   + V    +QY+++ AN LF +       +F +  +K++ A +  + F++
Sbjct: 64  GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123

Query: 144 NVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202
           +      +IN WV   T   + +++     D  T L L+NA+YFKG W  QF  + TR  
Sbjct: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183

Query: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
            F K +E +  + MM+++ +F  G ++D  +      QVLE+PY  +E+SM+++L     
Sbjct: 184 LF-KTNEEKKTVQMMFKEAKFKMG-YADEVHT-----QVLELPYVEEELSMVILLPDDNT 236

Query: 263 PLATLEPLVKAQLVEEWANSVK--KQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-D 319
            LA +E  +  +  + W NS K  K KV+V+LPR  +E+  DL+  L+ LG+ + F +  
Sbjct: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296

Query: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379
           A+ +G+S  K + LSK  HK F+EVNEEG+EAAA + ++  SR + + P+   DHPF F 
Sbjct: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356

Query: 380 IRNRRTGTILFMGRVMHP 397
           IR+ +T  ILF GR   P
Sbjct: 357 IRHHKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  218 bits (555), Expect = 8e-57
 Identities = 125/378 (33%), Positives = 211/378 (55%), Gaps = 13/378 (3%)

Query: 24  EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83
           EA    +++++  L       N+ FSP+SI+ A+ M+ +GA+GST  ++  ++     K+
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--YKD 63

Query: 84  GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
           G+     +   + V    +QY+++ AN LF +       +F +  +K++ A +  + F++
Sbjct: 64  GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123

Query: 144 NVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202
           +      +IN WV   T   + +++     D  T L L+NA+YFKG W  QF  + TR  
Sbjct: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183

Query: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
            F K +E +  + MM+++ +F  G ++D  +      QVLE+PY  +E+SM+++L     
Sbjct: 184 LF-KTNEEKKTVQMMFKEAKFKMG-YADEVHT-----QVLELPYVEEELSMVILLPDDNT 236

Query: 263 PLATLEPLVKAQLVEEWANSVK--KQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-D 319
            LA +E  +  +  + W NS K  K KV+V+LPR  +E+  DL+  L+ LG+ + F +  
Sbjct: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296

Query: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379
           A+ +G+S  K + LSK  HK F+EVNEEG+EAAA + ++  SR + + P+   DHPF F 
Sbjct: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356

Query: 380 IRNRRTGTILFMGRVMHP 397
           IR+ +T  ILF GR   P
Sbjct: 357 IRHHKTNCILFCGRFSSP 374


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  217 bits (552), Expect = 2e-56
 Identities = 125/367 (34%), Positives = 205/367 (55%), Gaps = 20/367 (5%)

Query: 42  EDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL--KNGEEFSFLKEFSNMVTA 99
           +++NI  SPLSI+ A  M +LGA   T +++     +D++  K  ++  F     N    
Sbjct: 104 DNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLY 163

Query: 100 KESQYVMKI--ANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANY-INKWVE 156
           +++    K+  AN LF       NE +  + +  + A +  +DF +N   +   INKWV 
Sbjct: 164 RKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVS 223

Query: 157 NNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPM 216
           N T   + D++     +  T L L+N +YFKG WKS+F PENTR   F K D       M
Sbjct: 224 NKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASM 283

Query: 217 MYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLV 276
           MYQ+G+F Y   ++G+       QVLE+P++GD+I+M+L+L + E  LA +E  +  +++
Sbjct: 284 MYQEGKFRYRRVAEGT-------QVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVL 336

Query: 277 EEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGL--SDNKEIFL 333
           +EW + +++  + V++PRF +E    LK+ L+ +G+ ++F  + + L G+      ++++
Sbjct: 337 QEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYV 396

Query: 334 SKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVI---VDHPFFFLIRNRRTGTILF 390
           S A HK+FLEVNEEGSEAAA + ++   R   L P  +    + PF   IR     TI+F
Sbjct: 397 SDAFHKAFLEVNEEGSEAAASTAVVIAGRS--LNPNRVTFKANRPFLVFIREVPLNTIIF 454

Query: 391 MGRVMHP 397
           MGRV +P
Sbjct: 455 MGRVANP 461


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  213 bits (543), Expect = 2e-55
 Identities = 124/392 (31%), Positives = 213/392 (54%), Gaps = 25/392 (6%)

Query: 24  EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-- 81
           EA      +++ + R + E+ NI +SP+SI  A+GM+ LGA+ +T ++I   + +D +  
Sbjct: 6   EANTKFMFDLFQQFRKSKEN-NIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTE 64

Query: 82  ------------KNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMK 129
                       ++G      ++           Y +KIAN LF +  +   +E+L  +K
Sbjct: 65  NTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIK 124

Query: 130 KYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKG 188
           K++  +V   DF+     +   IN WVE+ TN  +K+L         T L L+NA+YFKG
Sbjct: 125 KFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKG 184

Query: 189 NWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEG 248
            W+++F+ ENT+   F  +  +   + MM Q   F +    D   +      VLEIPY+G
Sbjct: 185 QWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAK------VLEIPYKG 238

Query: 249 DEISMMLVLSRQEVPLATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDV 306
            ++SM+++L  +   L  LE  + A+ + EW +  ++++  V+++LPRF +E+  DLKD 
Sbjct: 239 KDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDT 298

Query: 307 LKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMA-V 365
           L+ +G+  IF  DA+L+G++ +  + +SK +HK+F+EV EEG EAAA + ++ +   +  
Sbjct: 299 LRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPS 358

Query: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
              +   +HPF F IR  +T +ILF GR   P
Sbjct: 359 TNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  212 bits (540), Expect = 4e-55
 Identities = 126/376 (33%), Positives = 206/376 (54%), Gaps = 16/376 (4%)

Query: 30  SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSF 89
           +++++  L       NI  SP SI+ AM M+ LG +G+T  ++  +  +++++  E  S 
Sbjct: 12  ALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVE--EVHSR 69

Query: 90  LKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVAN 149
            +  +  +  + + Y++K+AN L+ +  ++   EFL   +K + A +  VDF      A 
Sbjct: 70  FQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDAR 129

Query: 150 Y-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDD 208
             IN+WV+  T   + +L++    D  T L L+NA+YFKGNWK +F  E T    F  + 
Sbjct: 130 KTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNK 189

Query: 209 ESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL----SRQEVPL 264
           +    + MMYQ+ +F YG   D         +VLE+PY+G+E+SM+++L      +   L
Sbjct: 190 KDRKTVKMMYQKKKFAYGYIEDLK------CRVLELPYQGEELSMVILLPDDIEDESTGL 243

Query: 265 ATLEPLVKAQLVEEWANSVKKQKVEVY--LPRFTVEQEIDLKDVLKALGITEIFIKD-AN 321
             +E  +  + + EW        +EV   LPRF +E+   L   L  LG+ ++F    A+
Sbjct: 244 KKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKAD 303

Query: 322 LTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381
           L+G+S  ++IF+SK +HKSF+EVNEEG+EAAA +  IA   M +       DHPF F IR
Sbjct: 304 LSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIR 363

Query: 382 NRRTGTILFMGRVMHP 397
           +  +G+ILF+GR   P
Sbjct: 364 HNSSGSILFLGRFSSP 379


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  198 bits (503), Expect = 8e-51
 Identities = 119/381 (31%), Positives = 204/381 (53%), Gaps = 19/381 (4%)

Query: 25  AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNG 84
           A    ++ +   L       N+  SP+SI+ A+ M+ LGA+G+T  ++  ++   SL   
Sbjct: 7   ASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQAL---SLNTE 63

Query: 85  EEFSFLKEFSNMVTAKE---SQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDF 141
           E+    + F +++T      +QY+++ AN LF +        F +   ++++A +  + F
Sbjct: 64  EDIH--RAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSF 121

Query: 142 SQNVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR 200
            +    +  +IN WV   T   +++L+     DA T L L+NA+YFKG W   F    TR
Sbjct: 122 IRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTR 181

Query: 201 TFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQ 260
              F  + E +  + MMYQ+  F      +         Q+LE+PY   E+S++++L   
Sbjct: 182 EMPFKINQEEQRPVQMMYQEATFKLAHVGEVR------AQLLELPYARKELSLLVLLPDD 235

Query: 261 EVPLATLEPLVKAQLVEEWA--NSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK 318
            V L+T+E  +  + +  W   + +K  +VEV LP+F ++++ D++ VL+ LGI + F +
Sbjct: 236 GVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQ 295

Query: 319 -DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV-LYPQVIVDHPF 376
             A+L+ +S  +++ LSK +HKSF+EVNEEG+EAAA S    ++   +   P+   DHPF
Sbjct: 296 GKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPF 355

Query: 377 FFLIRNRRTGTILFMGRVMHP 397
            F IR+ R  +ILF GR   P
Sbjct: 356 LFFIRHNRANSILFCGRFSSP 376


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  195 bits (496), Expect = 5e-50
 Identities = 116/411 (28%), Positives = 211/411 (51%), Gaps = 50/411 (12%)

Query: 30  SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-------- 81
           ++N++  L      +N+  SP SI+  M M+ +G++GST+ ++   + ++ +        
Sbjct: 12  ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71

Query: 82  --KNGEEFSFLKEF-------------------------SNMVTAKESQYVMKIANSLFV 114
             +N     F+++                          S+ + A    Y+++  N LF 
Sbjct: 72  TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFG 131

Query: 115 QNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFD 173
           +      EE++++ +KY+++    VDF +    A   IN WV+  T   + +L+     D
Sbjct: 132 EKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVD 191

Query: 174 AATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSN 233
             T + L+NAVYFKG WK+ F  +    + F  +      + MMY + +   G   D   
Sbjct: 192 GDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKA 251

Query: 234 EAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQL----VEEWANSVK--KQK 287
                 Q+LE+PY GD +SM L+L  +   ++T   L+++++    + +W +  K  + +
Sbjct: 252 ------QILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304

Query: 288 VEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNE 346
           VEVY+P+F +E+  +L+ +L+++G+ + F K  AN +G+S+  ++FLS+  H++ ++VNE
Sbjct: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364

Query: 347 EGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
           EG+EAAA +G +   R     PQ + DHPF FLI ++ T  ILF GR   P
Sbjct: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  195 bits (496), Expect = 5e-50
 Identities = 116/411 (28%), Positives = 211/411 (51%), Gaps = 50/411 (12%)

Query: 30  SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-------- 81
           ++N++  L      +N+  SP SI+  M M+ +G++GST+ ++   + ++ +        
Sbjct: 12  ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71

Query: 82  --KNGEEFSFLKEF-------------------------SNMVTAKESQYVMKIANSLFV 114
             +N     F+++                          S+ + A    Y+++  N LF 
Sbjct: 72  TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFG 131

Query: 115 QNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFD 173
           +      EE++++ +KY+++    VDF +    A   IN WV+  T   + +L+     D
Sbjct: 132 EKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVD 191

Query: 174 AATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSN 233
             T + L+NAVYFKG WK+ F  +    + F  +      + MMY + +   G   D   
Sbjct: 192 GDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKA 251

Query: 234 EAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQL----VEEWANSVK--KQK 287
                 Q+LE+PY GD +SM L+L  +   ++T   L+++++    + +W +  K  + +
Sbjct: 252 ------QILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304

Query: 288 VEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNE 346
           VEVY+P+F +E+  +L+ +L+++G+ + F K  AN +G+S+  ++FLS+  H++ ++VNE
Sbjct: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364

Query: 347 EGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
           EG+EAAA +G +   R     PQ + DHPF FLI ++ T  ILF GR   P
Sbjct: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score =  193 bits (491), Expect = 2e-49
 Identities = 113/376 (30%), Positives = 208/376 (55%), Gaps = 17/376 (4%)

Query: 28  DLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEF 87
           D +  +Y RL      +NI FSP+S++ ++ M+ LGA   T+ +I   +G++ L +  E 
Sbjct: 68  DFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN-LTHTPES 126

Query: 88  SFLKEFSNMV---TAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQN 144
           +  + F ++V   T       +K+ ++LFV+    +   FL  +K+ + A V   DFS  
Sbjct: 127 AIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNP 186

Query: 145 VAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TFS 203
                 IN  V+  T   V D++  +  D  T + L+N ++FK  W+  F PE TR  F 
Sbjct: 187 SIAQARINSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFP 244

Query: 204 FTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263
           F   ++  V +PMM+Q+ +F +G  ++ +        VL++ Y+GD ++  ++ S+ +  
Sbjct: 245 FLVGEQVTVHVPMMHQKEQFAFGVDTELN------CFVLQMDYKGDAVAFFVLPSKGK-- 296

Query: 264 LATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLT 323
           +  LE  + A+ + +W++S++K+ +EV++PRF++    +L+ +L  +GI  +F K+A+ +
Sbjct: 297 MRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFS 356

Query: 324 GLSDNKEIFLSKAIHKSFLEVNEEGSE--AAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381
           G++    + +SKA HK+ L+V+EEG+E  AA  +  I  S+    Y  V  +  F  +I 
Sbjct: 357 GIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMIT 416

Query: 382 NRRTGTILFMGRVMHP 397
           N+ T  ILF+G+V +P
Sbjct: 417 NKATDGILFLGKVENP 432


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  193 bits (491), Expect = 2e-49
 Identities = 125/398 (31%), Positives = 208/398 (52%), Gaps = 38/398 (9%)

Query: 32  NMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK--------- 82
           +++  +      +NI FSPLS++ A+GM+ LGA+  +  +I   + ++            
Sbjct: 14  DLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDP 73

Query: 83  ----NGEEFSFLKEFSNMVTAKESQ-----------YVMKIANSLFVQNGFHVNEEFLQM 127
               N ++   L   S +V+    Q           Y + IAN L+ +  F + +E+L  
Sbjct: 74  CLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYGEQEFPICQEYLDG 133

Query: 128 MKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYF 186
           + ++++  +  VDF +N   +   IN WVE  +   +K+L S    +A T L L+NAVYF
Sbjct: 134 VIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVLVNAVYF 193

Query: 187 KGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPY 246
           K  W++ F  ENT    F  +      + MM Q+G +  G   +         Q+LE+ Y
Sbjct: 194 KAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA------QILEMRY 247

Query: 247 EGDEISMMLVL-SRQEVPLATLEPLVKAQLVEE---WANS--VKKQKVEVYLPRFTVEQE 300
              ++SM ++L S  +  L  LE L +    E+   W++S  + ++ V +  PRFT+E  
Sbjct: 248 TKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDS 307

Query: 301 IDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIA 359
            DL  +L+ +GIT+IF +  A+LTG+S +  ++LSK IHK+F+EV+E G++AAA +G + 
Sbjct: 308 YDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAVV 367

Query: 360 ISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
             R    + +   +HPF F IR+ +T TILF GRV  P
Sbjct: 368 SERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  188 bits (478), Expect = 7e-48
 Identities = 116/385 (30%), Positives = 203/385 (52%), Gaps = 23/385 (5%)

Query: 25  AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEI------RHSMGY 78
           A A+   N++  +     + N+ FS LS+  A+ ++ LGAQ  +  +I        + GY
Sbjct: 7   ANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGY 66

Query: 79  DSLKNGEEF--SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAV 136
            +  N +    S LK   + + A    Y + I N LF +  +  ++++++  +K ++A V
Sbjct: 67  GNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKV 126

Query: 137 NHVDFSQNVA-VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFR 195
             VDF+ ++      INKWVEN T+  +K+++      ++  + L+NAVYFKG W+S F 
Sbjct: 127 ERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFT 186

Query: 196 PENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMML 255
              T    F     S   + MM+Q+ +F      D S       ++LE+ Y G  I+M +
Sbjct: 187 KSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPS------MKILELRYNGG-INMYV 239

Query: 256 VLSRQEVPLATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDVLKALGIT 313
           +L   +  L+ +E  +  Q + EW N   +  + VEV+ P+F +E+  ++K  L+ALG+ 
Sbjct: 240 LLPEND--LSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297

Query: 314 EIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIV 372
           +IF +  A+L+G++    +++S+ +HKS++EV EEG+EA A +G   + +          
Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357

Query: 373 DHPFFFLIRNRRTGTILFMGRVMHP 397
           DHPF F+I  R+   ILF G+V  P
Sbjct: 358 DHPFLFVI--RKDDIILFSGKVSCP 380


>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  188 bits (478), Expect = 7e-48
 Identities = 116/385 (30%), Positives = 203/385 (52%), Gaps = 23/385 (5%)

Query: 25  AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEI------RHSMGY 78
           A A+   N++  +     + N+ FS LS+  A+ ++ LGAQ  +  +I        + GY
Sbjct: 7   ANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGY 66

Query: 79  DSLKNGEEF--SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAV 136
            +  N +    S LK   + + A    Y + I N LF +  +  ++++++  +K ++A V
Sbjct: 67  GNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKV 126

Query: 137 NHVDFSQNVA-VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFR 195
             VDF+ ++      INKWVEN T+  +K+++      ++  + L+NAVYFKG W+S F 
Sbjct: 127 ERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFT 186

Query: 196 PENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMML 255
              T    F     S   + MM+Q+ +F      D S       ++LE+ Y G  I+M +
Sbjct: 187 KSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPS------MKILELRYNGG-INMYV 239

Query: 256 VLSRQEVPLATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDVLKALGIT 313
           +L   +  L+ +E  +  Q + EW N   +  + VEV+ P+F +E+  ++K  L+ALG+ 
Sbjct: 240 LLPEND--LSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297

Query: 314 EIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIV 372
           +IF +  A+L+G++    +++S+ +HKS++EV EEG+EA A +G   + +          
Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357

Query: 373 DHPFFFLIRNRRTGTILFMGRVMHP 397
           DHPF F+I  R+   ILF G+V  P
Sbjct: 358 DHPFLFVI--RKDDIILFSGKVSCP 380


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  188 bits (478), Expect = 7e-48
 Identities = 123/392 (31%), Positives = 203/392 (51%), Gaps = 34/392 (8%)

Query: 29  LSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQ---KEIRHSMGY------- 78
           L  +++  L+ T  D NI FSP+ I  A+GM+ LG +G+T    +E+ HS          
Sbjct: 11  LGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIK 69

Query: 79  ----DSLKNGEEF-----SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMK 129
               + ++N E        FL E S +     + Y + I N LF +  +   +++L  ++
Sbjct: 70  AEEKEVIENTEAVHQQFQKFLTEISKLT----NDYELNITNRLFGEKTYLFLQKYLDYVE 125

Query: 130 KYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKG 188
           KY++A++  VDF      +   IN WVE+ TN  +KDL       ++T L L+N VYFKG
Sbjct: 126 KYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKG 185

Query: 189 NWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEG 248
            W  +F+ ENT+   F  +  +   + MM Q   F +    D         ++L IPY+ 
Sbjct: 186 QWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQ------AKILGIPYKN 239

Query: 249 DEISMMLVLSRQEVPLATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDV 306
           +++SM ++L      L  +   +  + + EW +   ++++KV ++LPRF VE   DL+ V
Sbjct: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299

Query: 307 LKALGITEIFIK-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV 365
           L A+G+ + F +  A+ +G+S    ++  K +H SF+ V EEG+EAAA +G+      A 
Sbjct: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359

Query: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
            +  V  +HPF F IR+  + +ILF GR   P
Sbjct: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  187 bits (474), Expect = 2e-47
 Identities = 113/397 (28%), Positives = 214/397 (53%), Gaps = 30/397 (7%)

Query: 25  AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYD----- 79
           +I   ++ +  +L  + + +NI FS  SI+ ++ ++ LGA+G+T  ++   + ++     
Sbjct: 7   SINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGV 66

Query: 80  --------------SLKNGEEF-SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEF 124
                         +L N EE  S  +   + +      Y++K AN+++ +  +  + ++
Sbjct: 67  KCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKY 126

Query: 125 LQMMKKYFNAAVNHVDFSQ-NVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINA 183
           L+ MK YF A    V+F + +  +   IN WVE  T   +++L+     D+ T + L+NA
Sbjct: 127 LEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNA 186

Query: 184 VYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLE 243
           +YFKG W+ QF  +NT    F  ++ +   + MM+ + + +   F     +A G    L+
Sbjct: 187 LYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHI--FHIEKPKAVG----LQ 240

Query: 244 IPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEW--ANSVKKQKVEVYLPRFTVEQEI 301
           + Y+  ++S++++L      L  LE  +  + + EW  A+ ++  +V+++LP+F +E   
Sbjct: 241 LYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSY 300

Query: 302 DLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAI 360
           DLK  L ++G+++ F +  A+ +G+S  + +FLS   HK+F+E+NE+G+EAAA SG    
Sbjct: 301 DLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEID 360

Query: 361 SRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
            R+ V   +   +HPF F IR+ +T TILF GR+  P
Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]
          Length = 424

 Score =  180 bits (456), Expect = 2e-45
 Identities = 107/378 (28%), Positives = 203/378 (53%), Gaps = 21/378 (5%)

Query: 28  DLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEF 87
           + ++++Y  + A   + N + SP  ++L + +++ GA+GST +++  ++GY ++ +    
Sbjct: 32  EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGY-TVHDKRVK 90

Query: 88  SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAV 147
            FL      +        M++A SLFVQ G  ++  F++ +  + N+++   D S+  + 
Sbjct: 91  DFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNST 150

Query: 148 ANYINKWVENNT---------NNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPEN 198
           A   ++     T              + VS     A   L L++ + F+G W+ +F   +
Sbjct: 151 AIQTSEGASRETAGGGPSEGPGGWPWEQVSA----AFAQLVLVSTMSFQGTWRKRFSSTD 206

Query: 199 TRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS 258
           T+   FT      +Q+PMM+Q  E  YG+F D +    G   VLE+PY G  +S+ LVL 
Sbjct: 207 TQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVG---VLELPYLGSAVSLFLVLP 263

Query: 259 R-QEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFI 317
           R ++ PL+ +EP + A  +  W  S+++ +++V+LPRF ++ + +LK +L + G+T++F 
Sbjct: 264 RDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFD 323

Query: 318 K-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPF 376
              ANL G+S     ++S+AIHK+ +EV EEG++A+  + ++ + R  +  P    D PF
Sbjct: 324 PLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI--PIFKADRPF 381

Query: 377 FFLIRNRRTGTILFMGRV 394
            + +R   TG  +F  R+
Sbjct: 382 IYFLREPNTGITVFFDRI 399


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  179 bits (453), Expect = 5e-45
 Identities = 104/389 (26%), Positives = 208/389 (53%), Gaps = 16/389 (4%)

Query: 12  LQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKE 71
           ++ +  GAT    +  D + ++Y  L +    ++I FSP+SI++++ M+ LGA  ST+ +
Sbjct: 31  VEDLHVGATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQ 90

Query: 72  IRHSMGYDSLKNGEE--FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMK 129
           I   +G +  K+ E+      ++    +      + + + N+LF      + + F+  MK
Sbjct: 91  ILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMK 150

Query: 130 KYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGN 189
             + A     +F  +      IN +V   T   + DL+  ++ D+   + ++N ++FK  
Sbjct: 151 TLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVNYIFFKAK 208

Query: 190 WKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGD 249
           W++ F  + T+   F    E+ V++PMM ++ +++Y    D +       +V+ +PY+G+
Sbjct: 209 WETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHY--LLDRNLSC----RVVGVPYQGN 262

Query: 250 EISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKA 309
             ++ ++ S  E  +  +E  +  + + +W    KK+++E+YLP+F++E    L+ VL +
Sbjct: 263 ATALFILPS--EGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPS 320

Query: 310 LGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQ 369
           LGI+ +F   A+L+G+S++  I +S+ +HK+ +EV+E G+ AAA +G I   R A L  Q
Sbjct: 321 LGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQ 380

Query: 370 -VIVDHPFFFLIRNRRTGTILFMGRVMHP 397
            ++ + PF   I +     ILF+G+V  P
Sbjct: 381 RLVFNRPFLMFIVD---NNILFLGKVNRP 406


>gi|73858566 heparin cofactor II precursor [Homo sapiens]
          Length = 499

 Score =  177 bits (450), Expect = 1e-44
 Identities = 110/381 (28%), Positives = 197/381 (51%), Gaps = 25/381 (6%)

Query: 27  ADLSVNMYNRLR-ATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGE 85
           A  + N+Y  L+      +NI  +P+ I+ AMGM+ LG +G T +++   + +    N  
Sbjct: 131 AKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNAS 190

Query: 86  E-------FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNH 138
                    +  ++ ++ +  +   Y ++  N L++Q  F +  +F   +++Y+ A    
Sbjct: 191 SKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250

Query: 139 VDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPEN 198
            DFS    ++   N  +   T  L+KD +   + D AT + ++N +YFKG+W ++F  E 
Sbjct: 251 ADFSDPAFISK-TNNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPVEM 307

Query: 199 TRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS 258
           T   +F  ++   V++ MM  +G F        +N+      +L++ Y G  ISM++V+ 
Sbjct: 308 THNHNFRLNEREVVKVSMMQTKGNFL------AANDQELDCDILQLEYVGG-ISMLIVVP 360

Query: 259 RQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK 318
            +   + TLE  +  ++VE W  S+  +  EV LP+F +E+  +L + LK +GI  +F K
Sbjct: 361 HKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK 420

Query: 319 DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVS--GMIAISRMAVLYPQVIVDHPF 376
           + N+ G+SD + I +    H+  + VNEEG++A  V+  G + +S       +  VD PF
Sbjct: 421 NGNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV----RFTVDRPF 475

Query: 377 FFLIRNRRTGTILFMGRVMHP 397
            FLI   RT  +LFMGRV +P
Sbjct: 476 LFLIYEHRTSCLLFMGRVANP 496


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  177 bits (448), Expect = 2e-44
 Identities = 109/374 (29%), Positives = 194/374 (51%), Gaps = 14/374 (3%)

Query: 26  IADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYD--SLKN 83
           +A+ + ++Y +L       NI FSP+SIA A  M+ LG +  T  EI   + ++   +  
Sbjct: 54  LAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPE 113

Query: 84  GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
            +     +E    +   +SQ  +   N LF+  G  + ++FL+ +KK +++    V+F  
Sbjct: 114 AQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGD 173

Query: 144 NVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFS 203
                  IN +VE  T   + DLV  ++ D  T  AL+N ++FKG W+  F  ++T    
Sbjct: 174 TEEAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEED 231

Query: 204 FTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263
           F  D  + V++PMM + G F        S+       VL + Y G+  ++  +    E  
Sbjct: 232 FHVDQVTTVKVPMMKRLGMFNIQHCKKLSS------WVLLMKYLGNATAIFFL--PDEGK 283

Query: 264 LATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLT 323
           L  LE  +   ++ ++  +  ++   ++LP+ ++    DLK VL  LGIT++F   A+L+
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 324 GLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNR 383
           G+++   + LSKA+HK+ L ++E+G+EAA    + AI     + P+V  + PF FL+  +
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMS--IPPEVKFNKPFVFLMIEQ 401

Query: 384 RTGTILFMGRVMHP 397
            T + LFMG+V++P
Sbjct: 402 NTKSPLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  177 bits (448), Expect = 2e-44
 Identities = 109/374 (29%), Positives = 194/374 (51%), Gaps = 14/374 (3%)

Query: 26  IADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYD--SLKN 83
           +A+ + ++Y +L       NI FSP+SIA A  M+ LG +  T  EI   + ++   +  
Sbjct: 54  LAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPE 113

Query: 84  GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
            +     +E    +   +SQ  +   N LF+  G  + ++FL+ +KK +++    V+F  
Sbjct: 114 AQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGD 173

Query: 144 NVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFS 203
                  IN +VE  T   + DLV  ++ D  T  AL+N ++FKG W+  F  ++T    
Sbjct: 174 TEEAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEED 231

Query: 204 FTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263
           F  D  + V++PMM + G F        S+       VL + Y G+  ++  +    E  
Sbjct: 232 FHVDQVTTVKVPMMKRLGMFNIQHCKKLSS------WVLLMKYLGNATAIFFL--PDEGK 283

Query: 264 LATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLT 323
           L  LE  +   ++ ++  +  ++   ++LP+ ++    DLK VL  LGIT++F   A+L+
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 324 GLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNR 383
           G+++   + LSKA+HK+ L ++E+G+EAA    + AI     + P+V  + PF FL+  +
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMS--IPPEVKFNKPFVFLMIEQ 401

Query: 384 RTGTILFMGRVMHP 397
            T + LFMG+V++P
Sbjct: 402 NTKSPLFMGKVVNP 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,144,382
Number of Sequences: 37866
Number of extensions: 523536
Number of successful extensions: 1455
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1165
Number of HSP's gapped (non-prelim): 65
length of query: 410
length of database: 18,247,518
effective HSP length: 105
effective length of query: 305
effective length of database: 14,271,588
effective search space: 4352834340
effective search space used: 4352834340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.