Search of human proteins with 169881286

Search of human proteins with 169881286

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169881286 ATP-binding cassette, sub-family D, member 3
isoform b [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169881286 ATP-binding cassette, sub-family D, member 3 isofor...   470   e-133
gi|4506341 ATP-binding cassette, sub-family D, member 3 isoform ...   452   e-127
gi|9945308 ATP-binding cassette, sub-family D, member 2 [Homo sa...   123   2e-28
gi|7262393 ATP-binding cassette, sub-family D (ALD), member 1 [H...   121   6e-28
gi|4826958 ATP-binding cassette, sub-family D, member 4 [Homo sa...    71   7e-13
gi|197333692 leucine rich repeat containing 8 family, member B [...    30   1.8  
gi|21245134 leucine rich repeat containing 8 family, member B [H...    30   1.8  
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho...    29   4.0  
gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]                       28   6.9  
gi|111607465 IQ motif containing J isoform CaMBPv1 [Homo sapiens]      28   9.0  
gi|15812186 F-box only protein 3 isoform 1 [Homo sapiens]              28   9.0  
gi|15812188 F-box only protein 3 isoform 2 [Homo sapiens]              28   9.0  

>gi|169881286 ATP-binding cassette, sub-family D, member 3 isoform b
           [Homo sapiens]
          Length = 236

 Score =  470 bits (1209), Expect = e-133
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD 60
           MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD
Sbjct: 1   MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD 60

Query: 61  KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK 120
           KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK
Sbjct: 61  KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK 120

Query: 121 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN 180
           DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
Sbjct: 121 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN 180

Query: 181 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQVLGKILWH 236
           RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQVLGKILWH
Sbjct: 181 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQVLGKILWH 236


>gi|4506341 ATP-binding cassette, sub-family D, member 3 isoform a
           [Homo sapiens]
          Length = 659

 Score =  452 bits (1163), Expect = e-127
 Identities = 228/228 (100%), Positives = 228/228 (100%)

Query: 1   MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD 60
           MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD
Sbjct: 1   MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD 60

Query: 61  KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK 120
           KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK
Sbjct: 61  KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK 120

Query: 121 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN 180
           DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
Sbjct: 121 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN 180

Query: 181 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQ 228
           RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQ
Sbjct: 181 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQ 228


>gi|9945308 ATP-binding cassette, sub-family D, member 2 [Homo
           sapiens]
          Length = 740

 Score =  123 bits (308), Expect = 2e-28
 Identities = 83/238 (34%), Positives = 127/238 (53%), Gaps = 15/238 (6%)

Query: 11  RNSSLAGAAFLLLCL---LHKRRRALGLHGKKSGK--PPLQNNE------KEGKKERAVV 59
           R + L  AA+ L  L   + KR +  G HGKK     P  +N E         +K    V
Sbjct: 22  RAACLVAAAYALKTLYPIIGKRLKQSG-HGKKKAAAYPAAENTEILHCTETICEKPSPGV 80

Query: 60  DKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSR 119
           +  FF +L+++ KI+ P+    ETG+L L +V L+SRT+  +++      I   I+ +  
Sbjct: 81  NADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKP 140

Query: 120 KDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLD 179
           + F   L+ ++      + VN+ ++Y   +L L FR RL  + YE Y    TYYK+ N+D
Sbjct: 141 RTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMD 200

Query: 180 NRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKL---TSAIGAQVLGKIL 234
            R+ANPDQ LT+D+  F  SV  LYSNL+KP LD++L  + L    ++ GA  +G  L
Sbjct: 201 GRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTL 258


>gi|7262393 ATP-binding cassette, sub-family D (ALD), member 1 [Homo
           sapiens]
          Length = 745

 Score =  121 bits (303), Expect = 6e-28
 Identities = 64/176 (36%), Positives = 102/176 (57%)

Query: 56  RAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGII 115
           +A +++VF  RL+ +L+++ PR  C+ETG L L +  LVSRT+  V++ +    +   I+
Sbjct: 64  KAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIV 123

Query: 116 GRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKM 175
            +  + F   LL ++      + VN+ ++Y   +L L FR RL  + Y  Y    TYY++
Sbjct: 124 RKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRV 183

Query: 176 GNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQVLG 231
            N+D R+ NPDQ LT+DV  F  SV  LYSNL+KP LD+ +  + L  A  ++  G
Sbjct: 184 SNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAG 239


>gi|4826958 ATP-binding cassette, sub-family D, member 4 [Homo
           sapiens]
          Length = 606

 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 53/181 (29%), Positives = 92/181 (50%), Gaps = 12/181 (6%)

Query: 52  GKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIE 111
           G   R  +D  F  R +QILK++ P    +      L+ + L+  T  + ++I    LI 
Sbjct: 9   GAGARPRLDLQFLQRFLQILKVLFPSWSSQNA----LMFLTLLCLTLLEQFVIYQVGLIP 64

Query: 112 S---GIIGRSRKDFKRY-LLNFIAAMPLI--SLVNNFLKYGLNELKLCFRVRLTKYLYEE 165
           S   G++G   KD + +  L F+A M ++  S + +F ++  N L + +R  LT++L+  
Sbjct: 65  SQYYGVLGN--KDLEGFKTLTFLAVMLIVLNSTLKSFDQFTCNLLYVSWRKDLTEHLHRL 122

Query: 166 YLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAI 225
           Y +   YY +  L + I NPDQ ++QDVE+FC  +  + S L      +V Y ++   + 
Sbjct: 123 YFRGRAYYTLNVLRDDIDNPDQRISQDVERFCRQLSSMASKLIISPFTLVYYTYQCFQST 182

Query: 226 G 226
           G
Sbjct: 183 G 183


>gi|197333692 leucine rich repeat containing 8 family, member B
           [Homo sapiens]
          Length = 803

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 31/144 (21%), Positives = 67/144 (46%), Gaps = 11/144 (7%)

Query: 48  NEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNG 107
           ++KEG++ +A+ +KV   R+    K ++ R + K+    V++ V+++  TY   ++    
Sbjct: 227 DKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLII--TYVPYFLTHIT 284

Query: 108 TLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNF-----LKYGLN---ELKLCFRVRLT 159
             I+  +  ++   +KRY   +  A  +  ++ +F     + YGL     L    R  L 
Sbjct: 285 LEIDCSVDVQAFTGYKRYQCVYSLA-EIFKVLASFYVILVILYGLTSSYSLWWMLRSSLK 343

Query: 160 KYLYEEYLQAFTYYKMGNLDNRIA 183
           +Y +E   +   Y  + ++ N  A
Sbjct: 344 QYSFEALREKSNYSDIPDVKNDFA 367


>gi|21245134 leucine rich repeat containing 8 family, member B [Homo
           sapiens]
          Length = 803

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 31/144 (21%), Positives = 67/144 (46%), Gaps = 11/144 (7%)

Query: 48  NEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNG 107
           ++KEG++ +A+ +KV   R+    K ++ R + K+    V++ V+++  TY   ++    
Sbjct: 227 DKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLII--TYVPYFLTHIT 284

Query: 108 TLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNF-----LKYGLN---ELKLCFRVRLT 159
             I+  +  ++   +KRY   +  A  +  ++ +F     + YGL     L    R  L 
Sbjct: 285 LEIDCSVDVQAFTGYKRYQCVYSLA-EIFKVLASFYVILVILYGLTSSYSLWWMLRSSLK 343

Query: 160 KYLYEEYLQAFTYYKMGNLDNRIA 183
           +Y +E   +   Y  + ++ N  A
Sbjct: 344 QYSFEALREKSNYSDIPDVKNDFA 367


>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
           sapiens]
          Length = 328

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 126 LLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANP 185
           LL  +  MPL  + N  +++   EL LC  +   K L+  Y  AF    + +LD  +A  
Sbjct: 88  LLETLIVMPLDGMWNITVQWYAGEL-LCKVLSYLK-LFSMYAPAFMMVVI-SLDRSLAIT 144

Query: 186 DQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKL 221
             L  +   K   S+V L   LS  F    LYIF++
Sbjct: 145 RPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM 180


>gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]
          Length = 585

 Score = 28.1 bits (61), Expect = 6.9
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 2/69 (2%)

Query: 137 SLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIA--NPDQLLTQDVE 194
           S V N      + L LC+R  + K LY E+L     Y +     R+A     QL+ + + 
Sbjct: 7   SQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLT 66

Query: 195 KFCNSVVDL 203
            +C+S + L
Sbjct: 67  LYCDSYIQL 75


>gi|111607465 IQ motif containing J isoform CaMBPv1 [Homo sapiens]
          Length = 159

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 9/73 (12%)

Query: 140 NNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNS 199
           NN  KY LN   L  +V++ +  + EYLQ     +   L  R  +P  + +   EK  +S
Sbjct: 34  NNIEKYPLNLQPLESKVKIIQRAWREYLQ-----RQEPLGKRSPSPPSVSS---EKLSSS 85

Query: 200 V-VDLYSNLSKPF 211
           V ++ +S+ S PF
Sbjct: 86  VSMNTFSDSSTPF 98


>gi|15812186 F-box only protein 3 isoform 1 [Homo sapiens]
          Length = 471

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 9/77 (11%)

Query: 69  QILKIMVPRTFCKETGYLVLIAVMLVSRT-------YCDVWMIQNGTLIESGIIGRSRKD 121
           Q LK  +P TFC  TG    IAV              C   M +N   I+  IIG +  D
Sbjct: 188 QGLKYCLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTD 247

Query: 122 -FKRYLLNFIA-AMPLI 136
            F  Y+ N ++   P+I
Sbjct: 248 WFTSYVKNVVSGGFPII 264


>gi|15812188 F-box only protein 3 isoform 2 [Homo sapiens]
          Length = 415

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 9/77 (11%)

Query: 69  QILKIMVPRTFCKETGYLVLIAVMLVSRT-------YCDVWMIQNGTLIESGIIGRSRKD 121
           Q LK  +P TFC  TG    IAV              C   M +N   I+  IIG +  D
Sbjct: 188 QGLKYCLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTD 247

Query: 122 -FKRYLLNFIA-AMPLI 136
            F  Y+ N ++   P+I
Sbjct: 248 WFTSYVKNVVSGGFPII 264


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,793,537
Number of Sequences: 37866
Number of extensions: 307485
Number of successful extensions: 867
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 861
Number of HSP's gapped (non-prelim): 12
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.