Guide to the Human Genome
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Search of human proteins with 169808399

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169808399 prenyl diphosphate synthase, subunit 2 [Homo
sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169808399 prenyl diphosphate synthase, subunit 2 [Homo sapiens]    790   0.0  
gi|50659086 prenyl diphosphate synthase, subunit 1 [Homo sapiens]      91   2e-18
gi|8923754 serine/threonine kinase 32B [Homo sapiens]                  31   1.7  
gi|21735548 centrosomal protein 2 [Homo sapiens]                       30   2.9  
gi|27437019 calcium/calmodulin-dependent protein kinase kinase 2...    30   5.0  
gi|27437017 calcium/calmodulin-dependent protein kinase kinase 2...    30   5.0  
gi|27437015 calcium/calmodulin-dependent protein kinase kinase 2...    30   5.0  
gi|27437027 calcium/calmodulin-dependent protein kinase kinase 2...    30   5.0  
gi|27437025 calcium/calmodulin-dependent protein kinase kinase 2...    30   5.0  
gi|27437023 calcium/calmodulin-dependent protein kinase kinase 2...    30   5.0  
gi|27437021 calcium/calmodulin-dependent protein kinase kinase 2...    30   5.0  
gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]             30   5.0  
gi|71896667 retinaldehyde binding protein 1-like 2 [Homo sapiens]      30   5.0  
gi|239749659 PREDICTED: hypothetical protein XP_002347139 [Homo ...    29   8.6  
gi|239743930 PREDICTED: hypothetical protein XP_002342992 [Homo ...    29   8.6  

>gi|169808399 prenyl diphosphate synthase, subunit 2 [Homo sapiens]
          Length = 399

 Score =  790 bits (2041), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MNFRQLLLHLPRYLGASGSPRRLWWSPSLDTISSVGSWRGRSSKSPAHWNQVVSEAEKIV 60
           MNFRQLLLHLPRYLGASGSPRRLWWSPSLDTISSVGSWRGRSSKSPAHWNQVVSEAEKIV
Sbjct: 1   MNFRQLLLHLPRYLGASGSPRRLWWSPSLDTISSVGSWRGRSSKSPAHWNQVVSEAEKIV 60

Query: 61  GYPTSFMSLRCLLSDELSNIAMQVRKLVGTQHPLLTTARGLVHDSWNSLQLRGLVVLLIS 120
           GYPTSFMSLRCLLSDELSNIAMQVRKLVGTQHPLLTTARGLVHDSWNSLQLRGLVVLLIS
Sbjct: 61  GYPTSFMSLRCLLSDELSNIAMQVRKLVGTQHPLLTTARGLVHDSWNSLQLRGLVVLLIS 120

Query: 121 KAAGPSSVNTSCQNYDMVSGIYSCQRSLAEITELIHIALLVHRGIVNLNELQSSDGPLKD 180
           KAAGPSSVNTSCQNYDMVSGIYSCQRSLAEITELIHIALLVHRGIVNLNELQSSDGPLKD
Sbjct: 121 KAAGPSSVNTSCQNYDMVSGIYSCQRSLAEITELIHIALLVHRGIVNLNELQSSDGPLKD 180

Query: 181 MQFGNKIAILSGDFLLANACNGLALLQNTKVVELLASALMDLVQGVYHENSTSKESYITD 240
           MQFGNKIAILSGDFLLANACNGLALLQNTKVVELLASALMDLVQGVYHENSTSKESYITD
Sbjct: 181 MQFGNKIAILSGDFLLANACNGLALLQNTKVVELLASALMDLVQGVYHENSTSKESYITD 240

Query: 241 DIGISTWKEQTFLSHGALLAKSCQAAMELAKHDAEVQNMAFQYGKHMAMSHKINSDVQPF 300
           DIGISTWKEQTFLSHGALLAKSCQAAMELAKHDAEVQNMAFQYGKHMAMSHKINSDVQPF
Sbjct: 241 DIGISTWKEQTFLSHGALLAKSCQAAMELAKHDAEVQNMAFQYGKHMAMSHKINSDVQPF 300

Query: 301 IKEKTSDSMTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGRLDYAKLRERIKAGKGVTS 360
           IKEKTSDSMTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGRLDYAKLRERIKAGKGVTS
Sbjct: 301 IKEKTSDSMTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGRLDYAKLRERIKAGKGVTS 360

Query: 361 AIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS 399
           AIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS
Sbjct: 361 AIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS 399


>gi|50659086 prenyl diphosphate synthase, subunit 1 [Homo sapiens]
          Length = 415

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 72/255 (28%), Positives = 129/255 (50%), Gaps = 16/255 (6%)

Query: 141 IYSCQRSLAEITELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLANAC 200
           + + QR++A I E+IH A LVH  +++    +     +  + +G K A+L+GD +L+ A 
Sbjct: 158 VQASQRAIALIAEMIHTASLVHDDVIDDASSRRGKHTVNKI-WGEKKAVLAGDLILSAAS 216

Query: 201 NGLALLQNTKVVELLASALMDLVQGVYHENSTSKESYITDDIGISTWKEQTFLSHGALLA 260
             LA + NT V+ +L   + DLV+G + +   SKE+   ++   + + E+TF    +L+A
Sbjct: 217 IALARIGNTTVISILTQVIEDLVRGEFLQLG-SKEN---ENERFAHYLEKTFKKTASLIA 272

Query: 261 KSCQAAMELAKHDAEVQNMAFQYGKHMAMSHKINSDVQPF------IKEKTSDSMTFNLN 314
            SC+A   L   D  V  +A+QYGK++ ++ ++  DV  F      + + TS  +   L 
Sbjct: 273 NSCKAVSVLGCPDPVVHEIAYQYGKNVGIAFQLIDDVLDFTSCSDQMGKPTSADLKLGLA 332

Query: 315 SAPVVLH-QEFLGRDLWIKQIGEAQEKGRLDYAKLRERIKAGKGVTSAIDLCRYHGNKAL 373
           + PV+   Q+F   +  I +       G +D A  R+ +    GV     L + + ++A+
Sbjct: 333 TGPVLFACQQFPEMNAMIMR--RFSLPGDVDRA--RQYVLQSDGVQQTTYLAQQYCHEAI 388

Query: 374 EALESFPPSEARSAL 388
             +    PS  R AL
Sbjct: 389 REISKLRPSPERDAL 403


>gi|8923754 serine/threonine kinase 32B [Homo sapiens]
          Length = 414

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 14/111 (12%)

Query: 70  RCLLSDELSNIAMQVRKLVGTQHPLLTTARGLVHDSWNSLQLRGLVVLLISKAAGPSSVN 129
           +C+  DE+ N+  +++ + G +HP L        + W S Q    + +++    G     
Sbjct: 58  KCIERDEVRNVFRELQIMQGLEHPFLV-------NLWYSFQDEEDMFMVVDLLLGGDLRY 110

Query: 130 TSCQNYDMVSG---IYSCQRSLA-EITELIHIALLVHRGIVNLNELQSSDG 176
              QN     G   +Y C+ +LA E  +  HI   +HR I   N L    G
Sbjct: 111 HLQQNVHFTEGTVKLYICELALALEYLQRYHI---IHRDIKPDNILLDEHG 158


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 4/121 (3%)

Query: 257  ALLAKSCQAAMELAKHDAEVQNMAFQYGKHMAMSHKINSDVQPFIKEKTSDSMTFNLNSA 316
            ALLA   Q A +  +H+ E + +   + +  A+  + + +++    E  S         A
Sbjct: 1902 ALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARA 1961

Query: 317  PVVLHQEFLGRDLWIKQIGEAQEKGRLDYAKLRERIKAGKGVTSA-IDLCRYHGNKALEA 375
                 QE LG+        + +E+  L+ A+L   ++A      A +D C+ H  +  EA
Sbjct: 1962 RAEALQEALGK---AHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEA 2018

Query: 376  L 376
            L
Sbjct: 2019 L 2019


>gi|27437019 calcium/calmodulin-dependent protein kinase kinase 2
           beta isoform 4 [Homo sapiens]
          Length = 498

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/46 (34%), Positives = 21/46 (45%)

Query: 153 ELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLAN 198
           E +H   ++HR I   N L   DG +K   FG        D LL+N
Sbjct: 301 EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN 346


>gi|27437017 calcium/calmodulin-dependent protein kinase kinase 2
           beta isoform 2 [Homo sapiens]
          Length = 541

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/46 (34%), Positives = 21/46 (45%)

Query: 153 ELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLAN 198
           E +H   ++HR I   N L   DG +K   FG        D LL+N
Sbjct: 301 EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN 346


>gi|27437015 calcium/calmodulin-dependent protein kinase kinase 2
           beta isoform 1 [Homo sapiens]
          Length = 588

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/46 (34%), Positives = 21/46 (45%)

Query: 153 ELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLAN 198
           E +H   ++HR I   N L   DG +K   FG        D LL+N
Sbjct: 301 EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN 346


>gi|27437027 calcium/calmodulin-dependent protein kinase kinase 2
           beta isoform 2 [Homo sapiens]
          Length = 541

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/46 (34%), Positives = 21/46 (45%)

Query: 153 ELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLAN 198
           E +H   ++HR I   N L   DG +K   FG        D LL+N
Sbjct: 301 EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN 346


>gi|27437025 calcium/calmodulin-dependent protein kinase kinase 2
           beta isoform 3 [Homo sapiens]
          Length = 545

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/46 (34%), Positives = 21/46 (45%)

Query: 153 ELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLAN 198
           E +H   ++HR I   N L   DG +K   FG        D LL+N
Sbjct: 301 EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN 346


>gi|27437023 calcium/calmodulin-dependent protein kinase kinase 2
           beta isoform 6 [Homo sapiens]
          Length = 490

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/46 (34%), Positives = 21/46 (45%)

Query: 153 ELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLAN 198
           E +H   ++HR I   N L   DG +K   FG        D LL+N
Sbjct: 301 EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN 346


>gi|27437021 calcium/calmodulin-dependent protein kinase kinase 2
           beta isoform 5 [Homo sapiens]
          Length = 533

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/46 (34%), Positives = 21/46 (45%)

Query: 153 ELIHIALLVHRGIVNLNELQSSDGPLKDMQFGNKIAILSGDFLLAN 198
           E +H   ++HR I   N L   DG +K   FG        D LL+N
Sbjct: 301 EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN 346


>gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]
          Length = 1016

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 7/102 (6%)

Query: 16  ASGSPRRLWWS--PSLDTISSVGSWRGRSSKSPAHWNQVVSEAEKIVGYPTSFMSLRCLL 73
           AS +PR L     P+L   S+     G   + P    +V    E++         LR +L
Sbjct: 140 ASSTPRPLARPARPNLSGSSAGSPLSGLGGEGPGESEKVQQLEEQVQSLTKELQGLRGVL 199

Query: 74  SDELSNIAMQVRKLV-----GTQHPLLTTARGLVHDSWNSLQ 110
                 +A  V++ V     G Q P    AR  VH++ N +Q
Sbjct: 200 QGLSGRLAEDVQRAVETAFNGRQQPADAAARPGVHETLNEIQ 241


>gi|71896667 retinaldehyde binding protein 1-like 2 [Homo sapiens]
          Length = 327

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 26/118 (22%), Positives = 47/118 (39%), Gaps = 8/118 (6%)

Query: 211 VVELLASALMDLVQGVYHENSTSKESYITDDIGISTWKEQTFLSHGALLAKSCQAAMELA 270
           +V++L + L+ L   +        E  +   + I  W   TF     L     + A+E  
Sbjct: 133 LVDILRAILLSLEAMI-----EDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGL 187

Query: 271 KHDAEVQNMAFQYGKHMAMSHKINSDVQPFIKEKTSDSMTF---NLNSAPVVLHQEFL 325
           +     +     +       H + + ++PF+KEKT   +     NLNS   ++H E L
Sbjct: 188 QDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEIL 245


>gi|239749659 PREDICTED: hypothetical protein XP_002347139 [Homo
           sapiens]
          Length = 369

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 10/73 (13%)

Query: 97  TARGLVHDSW-NSLQLRGLVVLLISKAAGPSSVNT-------SCQNYDMVSGIY--SCQR 146
           T R L+  +W N   ++G  +L +     P SV T       SC+N D++ GI+  S + 
Sbjct: 98  TRRDLIRKTWGNVTSVQGHPILTLFALGMPVSVTTQKEINKESCKNNDIIEGIFLDSSEN 157

Query: 147 SLAEITELIHIAL 159
              +I  +I  A+
Sbjct: 158 QTLKIIAMIQWAV 170


>gi|239743930 PREDICTED: hypothetical protein XP_002342992 [Homo
           sapiens]
          Length = 369

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 10/73 (13%)

Query: 97  TARGLVHDSW-NSLQLRGLVVLLISKAAGPSSVNT-------SCQNYDMVSGIY--SCQR 146
           T R L+  +W N   ++G  +L +     P SV T       SC+N D++ GI+  S + 
Sbjct: 98  TRRDLIRKTWGNVTSVQGHPILTLFALGMPVSVTTQKEINKESCKNNDIIEGIFLDSSEN 157

Query: 147 SLAEITELIHIAL 159
              +I  +I  A+
Sbjct: 158 QTLKIIAMIQWAV 170


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.131    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,620,076
Number of Sequences: 37866
Number of extensions: 532862
Number of successful extensions: 1545
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1533
Number of HSP's gapped (non-prelim): 17
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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