Guide to the Human Genome
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Search of human proteins with 11141875

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11141875 interleukin 21 [Homo sapiens]
         (162 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11141875 interleukin 21 [Homo sapiens]                             332   1e-91
gi|26787984 interleukin 15 preproprotein [Homo sapiens]                38   0.003
gi|10835153 interleukin 15 preproprotein [Homo sapiens]                38   0.003
gi|19923899 coiled-coil domain containing 45 [Homo sapiens]            29   1.6  
gi|224593754 AXIN1 up-regulated 1 [Homo sapiens]                       29   2.0  
gi|93277115 ataxin 7-like 2 [Homo sapiens]                             28   3.5  
gi|40548378 syndecan 2 precursor [Homo sapiens]                        27   5.9  
gi|169167201 PREDICTED: hypothetical protein [Homo sapiens]            27   5.9  
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi...    27   5.9  
gi|157168329 formin 1 [Homo sapiens]                                   27   7.7  
gi|169172033 PREDICTED: hypothetical protein [Homo sapiens]            27   7.7  
gi|169170051 PREDICTED: hypothetical protein [Homo sapiens]            27   7.7  
gi|239509128 PREDICTED: hypothetical protein [Homo sapiens]            27   7.7  
gi|59709436 tumor necrosis factor, alpha-induced protein 8-like ...    27   7.7  

>gi|11141875 interleukin 21 [Homo sapiens]
          Length = 162

 Score =  332 bits (850), Expect = 1e-91
 Identities = 162/162 (100%), Positives = 162/162 (100%)

Query: 1   MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEF 60
           MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEF
Sbjct: 1   MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEF 60

Query: 61  LPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRL 120
           LPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRL
Sbjct: 61  LPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRL 120

Query: 121 TCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS 162
           TCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
Sbjct: 121 TCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS 162


>gi|26787984 interleukin 15 preproprotein [Homo sapiens]
          Length = 162

 Score = 38.1 bits (87), Expect = 0.003
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 15/116 (12%)

Query: 43  IDIVDQLKNYVNDLVPEF-----LPAPEDVETNCEWSAFSCF----QKAQLKSANTGNNE 93
           ++++  LK  + DL+        L    DV  +C+ +A  CF    Q   L+S +   ++
Sbjct: 51  VNVISDLKK-IEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHD 109

Query: 94  RIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIH 149
            + N+ I  L     S+N    +     C  C+  E+K  KEFL+ F  ++Q  I+
Sbjct: 110 TVENLII--LANNSLSSNGNVTESG---CKECEELEEKNIKEFLQSFVHIVQMFIN 160


>gi|10835153 interleukin 15 preproprotein [Homo sapiens]
          Length = 162

 Score = 38.1 bits (87), Expect = 0.003
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 15/116 (12%)

Query: 43  IDIVDQLKNYVNDLVPEF-----LPAPEDVETNCEWSAFSCF----QKAQLKSANTGNNE 93
           ++++  LK  + DL+        L    DV  +C+ +A  CF    Q   L+S +   ++
Sbjct: 51  VNVISDLKK-IEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHD 109

Query: 94  RIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIH 149
            + N+ I  L     S+N    +     C  C+  E+K  KEFL+ F  ++Q  I+
Sbjct: 110 TVENLII--LANNSLSSNGNVTESG---CKECEELEEKNIKEFLQSFVHIVQMFIN 160


>gi|19923899 coiled-coil domain containing 45 [Homo sapiens]
          Length = 821

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 4/50 (8%)

Query: 105 RKPPSTNAGRRQKHRLTCPSCDS-YEKKPPKEFLERFKSLLQKMIHQHLS 153
           RKPP    G+R ++R T  SC+S + ++P K   E+    + + + Q LS
Sbjct: 334 RKPPK---GKRNENRATASSCNSPFPQRPRKRLTEQELHDVSEKLSQRLS 380


>gi|224593754 AXIN1 up-regulated 1 [Homo sapiens]
          Length = 589

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 9/53 (16%)

Query: 77  SCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYE 129
           SCF    L+ +  G+   +   S+      PPS +AGR     L+  SCDS+E
Sbjct: 463 SCFLNGGLEGSREGS---LPGTSV------PPSMDAGRSSSVDLSLSSCDSFE 506


>gi|93277115 ataxin 7-like 2 [Homo sapiens]
          Length = 722

 Score = 28.1 bits (61), Expect = 3.5
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 5/49 (10%)

Query: 106 KPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSS 154
           +PP   A      RL  P C  + ++     L+RF S L  M+ +HLS+
Sbjct: 406 RPPRPQAFCTFGSRLVSPGCYVFSRR-----LDRFCSALSSMLERHLST 449


>gi|40548378 syndecan 2 precursor [Homo sapiens]
          Length = 201

 Score = 27.3 bits (59), Expect = 5.9
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 14/98 (14%)

Query: 47  DQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNE--------RIINV 98
           D+ K +++D   +  PA ED     E  + S F++ ++ +A               I+ +
Sbjct: 108 DKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLL 167

Query: 99  SIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEF 136
             +  K+   S + G R+      PS  +Y+K P KEF
Sbjct: 168 VYRMRKKDEGSYDLGERK------PSSAAYQKAPTKEF 199


>gi|169167201 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 145

 Score = 27.3 bits (59), Expect = 5.9
 Identities = 12/44 (27%), Positives = 23/44 (52%)

Query: 90  GNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPP 133
           G+ ER+ + +  + + +P S+ A   + HR   PS  ++   PP
Sbjct: 45  GDTERLTDYATARARAQPASSAAQLPRSHRPPAPSAPAHLPAPP 88


>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo
           sapiens]
          Length = 1270

 Score = 27.3 bits (59), Expect = 5.9
 Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 23  LVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPED 66
           L  K   +  + + + + Q  D+  QL+N + +L  E LP PED
Sbjct: 262 LTKKKEGETVEPYKVNLSQ--DLEHQLQNIIQELNLEILPPPED 303


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 17/154 (11%)

Query: 12   VICLMVIFLGTLVHKSSSQGQ-DRHMIRMRQLIDIVDQLKNYVN--DLVPEFLPAPEDVE 68
            ++ L++ F   +   + ++GQ D + + +   +  V    N +N  D V ++     D E
Sbjct: 957  ILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYDQE 1016

Query: 69   TNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSY 128
               E S F   +      A+    E +I   ++KLKR+  ++     ++  + C      
Sbjct: 1017 AGTEKSVFPLPEPQDFFLASQVKFEDLIK-DLRKLKRQLEASE----KQMVVVC------ 1065

Query: 129  EKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS 162
             K+ PKE+L+ FK  L++   +  + + H  E+S
Sbjct: 1066 -KESPKEYLQPFKDKLEEFFQK--AKKEHKMEES 1096


>gi|169172033 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 116

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 12/28 (42%), Positives = 17/28 (60%)

Query: 73  WSAFSCFQKAQLKSANTGNNERIINVSI 100
           W A  C + AQ  + NTGN+ER   +S+
Sbjct: 3   WKASFCSRTAQPANQNTGNHERAPALSL 30


>gi|169170051 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 116

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 12/28 (42%), Positives = 17/28 (60%)

Query: 73  WSAFSCFQKAQLKSANTGNNERIINVSI 100
           W A  C + AQ  + NTGN+ER   +S+
Sbjct: 3   WKASFCSRTAQPANQNTGNHERAPALSL 30


>gi|239509128 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 116

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 12/28 (42%), Positives = 17/28 (60%)

Query: 73  WSAFSCFQKAQLKSANTGNNERIINVSI 100
           W A  C + AQ  + NTGN+ER   +S+
Sbjct: 3   WKASFCSRTAQPANQNTGNHERAPALSL 30


>gi|59709436 tumor necrosis factor, alpha-induced protein 8-like 3
           [Homo sapiens]
          Length = 292

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 9/32 (28%), Positives = 19/32 (59%)

Query: 127 SYEKKPPKEFLERFKSLLQKMIHQHLSSRTHG 158
           ++++      L   K L+ +++ +HL+ RTHG
Sbjct: 216 TFDRNVLSNLLHECKDLVHELVQRHLTPRTHG 247


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,693,655
Number of Sequences: 37866
Number of extensions: 272190
Number of successful extensions: 849
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 840
Number of HSP's gapped (non-prelim): 14
length of query: 162
length of database: 18,247,518
effective HSP length: 94
effective length of query: 68
effective length of database: 14,688,114
effective search space: 998791752
effective search space used: 998791752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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