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Search of human proteins with 169173216
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2
[Homo sapiens]
(364 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2 ... 733 0.0
gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sap... 303 2e-82
gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2 ... 252 4e-67
gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei... 132 5e-31
gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein... 132 5e-31
gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ... 130 1e-30
gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sap... 64 2e-10
gi|66932902 SREBF chaperone protein [Homo sapiens] 32 1.2
gi|7524354 dimethylarginine dimethylaminohydrolase 2 [Homo sapiens] 31 2.0
gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens] 30 4.4
gi|169217659 PREDICTED: similar to ectonucleotide pyrophosphatas... 29 5.8
gi|169167316 PREDICTED: similar to ectonucleotide pyrophosphatas... 29 5.8
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens] 29 7.6
gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens] 29 7.6
gi|223633890 hypothetical protein LOC729956 [Homo sapiens] 28 9.9
gi|194394139 notum pectinacetylesterase homolog [Homo sapiens] 28 9.9
>gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2
[Homo sapiens]
Length = 364
Score = 733 bits (1891), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
Sbjct: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
Query: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120
RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE
Sbjct: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120
Query: 121 EFYEASPYEPVTSRLSDIFRLASIFSVGSYRGSELRAAPMLALPVGTMAALRMLTRQMRK 180
EFYEASPYEPVTSRLSDIFRLASIFSVGSYRGSELRAAPMLALPVGTMAALRMLTRQMRK
Sbjct: 121 EFYEASPYEPVTSRLSDIFRLASIFSVGSYRGSELRAAPMLALPVGTMAALRMLTRQMRK 180
Query: 181 LLGLQLTESAPFYLLPRDNWAPRKLWVSVLQGPLPAMRAGLWGLCRSLLIASVDSAPPRE 240
LLGLQLTESAPFYLLPRDNWAPRKLWVSVLQGPLPAMRAGLWGLCRSLLIASVDSAPPRE
Sbjct: 181 LLGLQLTESAPFYLLPRDNWAPRKLWVSVLQGPLPAMRAGLWGLCRSLLIASVDSAPPRE 240
Query: 241 ALGLGPEAGDPAFVQAPPALLGLLSKRIDGRIQLMAKEQVWGAREWGLWRRGEVDCQEVE 300
ALGLGPEAGDPAFVQAPPALLGLLSKRIDGRIQLMAKEQVWGAREWGLWRRGEVDCQEVE
Sbjct: 241 ALGLGPEAGDPAFVQAPPALLGLLSKRIDGRIQLMAKEQVWGAREWGLWRRGEVDCQEVE 300
Query: 301 RGDPVTLTALGAARRKAASLSAGGGAGGIDIFPLLFSSALSLSLSTPVTSGSCQSVEGFA 360
RGDPVTLTALGAARRKAASLSAGGGAGGIDIFPLLFSSALSLSLSTPVTSGSCQSVEGFA
Sbjct: 301 RGDPVTLTALGAARRKAASLSAGGGAGGIDIFPLLFSSALSLSLSTPVTSGSCQSVEGFA 360
Query: 361 GTKV 364
GTKV
Sbjct: 361 GTKV 364
>gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo
sapiens]
Length = 464
Score = 303 bits (776), Expect = 2e-82
Identities = 146/146 (100%), Positives = 146/146 (100%)
Query: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
Sbjct: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
Query: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120
RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE
Sbjct: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120
Query: 121 EFYEASPYEPVTSRLSDIFRLASIFS 146
EFYEASPYEPVTSRLSDIFRLASIFS
Sbjct: 121 EFYEASPYEPVTSRLSDIFRLASIFS 146
>gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2
[Homo sapiens]
Length = 140
Score = 252 bits (643), Expect = 4e-67
Identities = 123/140 (87%), Positives = 125/140 (89%)
Query: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
Sbjct: 1 MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
Query: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120
RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTE E
Sbjct: 61 RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEAE 120
Query: 121 EFYEASPYEPVTSRLSDIFR 140
+ E +L FR
Sbjct: 121 FSLKGEVSEVTELQLKPNFR 140
>gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein
[Homo sapiens]
Length = 460
Score = 132 bits (332), Expect = 5e-31
Identities = 62/115 (53%), Positives = 85/115 (73%), Gaps = 6/115 (5%)
Query: 38 VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92
+DCV+A++ C E +CS++YRTLRQC+AG++ N LA+ EC++A+E L++ LY+
Sbjct: 27 LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86
Query: 93 CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSV 147
CRCKRGMKKE CL+IYWS++ L +G + E SPYEPV SRLSDIFR+ SV
Sbjct: 87 CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFISV 140
>gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein
[Homo sapiens]
Length = 460
Score = 132 bits (332), Expect = 5e-31
Identities = 62/115 (53%), Positives = 85/115 (73%), Gaps = 6/115 (5%)
Query: 38 VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92
+DCV+A++ C E +CS++YRTLRQC+AG++ N LA+ EC++A+E L++ LY+
Sbjct: 27 LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86
Query: 93 CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSV 147
CRCKRGMKKE CL+IYWS++ L +G + E SPYEPV SRLSDIFR+ SV
Sbjct: 87 CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFISV 140
>gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
[Homo sapiens]
Length = 465
Score = 130 bits (328), Expect = 1e-30
Identities = 61/114 (53%), Positives = 84/114 (73%), Gaps = 6/114 (5%)
Query: 38 VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92
+DCV+A++ C E +CS++YRTLRQC+AG++ N LA+ EC++A+E L++ LY+
Sbjct: 27 LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86
Query: 93 CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFS 146
CRCKRGMKKE CL+IYWS++ L +G + E SPYEPV SRLSDIFR+ S
Sbjct: 87 CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFIS 139
>gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo
sapiens]
Length = 400
Score = 63.9 bits (154), Expect = 2e-10
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 9/102 (8%)
Query: 40 CVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKE------CQAALEVLQESPLYDC 93
C++A C A+ CS+ Y L C + +T L ++E C A + L+ S L C
Sbjct: 44 CLQARRKCQADPTCSAAYHHLDSCTSSI--STPLPSEEPSVPADCLEAAQQLRNSSLIGC 101
Query: 94 RCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYE-PVTSR 134
C R MK ++ CL IYW++H + G + SPYE VTS+
Sbjct: 102 MCHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSK 143
>gi|66932902 SREBF chaperone protein [Homo sapiens]
Length = 1279
Score = 31.6 bits (70), Expect = 1.2
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 17/113 (15%)
Query: 233 VDSAPPREALGLGPEAGDPAFVQAPPALLGLLSKRIDGRIQLMAKE----QVWGAREWGL 288
+ AP E G PE G P+ AP A + S + G + ++ + +VW A E
Sbjct: 942 LSQAPEDE--GGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIE--- 996
Query: 289 WRRGEVDCQEVERGDPVTLTALGAARRKAASLSAGGGAGGIDIFPLLFSSALS 341
G + C E +T R AA L+ G +D F L +ALS
Sbjct: 997 ---GVLCCSSEEVSSGITALVFLDKRIVAARLN-----GSLDFFSLETHTALS 1041
>gi|7524354 dimethylarginine dimethylaminohydrolase 2 [Homo sapiens]
Length = 285
Score = 30.8 bits (68), Expect = 2.0
Identities = 17/41 (41%), Positives = 21/41 (51%)
Query: 221 LWGLCRSLLIASVDSAPPREALGLGPEAGDPAFVQAPPALL 261
L G R L + PP E+L LGP GD A +Q AL+
Sbjct: 48 LGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALI 88
>gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]
Length = 467
Score = 29.6 bits (65), Expect = 4.4
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 112 IHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSVGSYRGSELRAAPMLALPVGTMAAL 171
+HLGL GE F A PY PV S +D + + F +Y + +A G A
Sbjct: 184 VHLGL-RGELFGRADPYRPVASPRTDPYAAGAQFP--NYSPMNMNMGVNVAAHHGPGAFF 240
Query: 172 RMLTRQMRKLLGLQLTESA 190
R + + +++ L + + A
Sbjct: 241 RYMRQPIKQELSCKWIDEA 259
>gi|169217659 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
Length = 542
Score = 29.3 bits (64), Expect = 5.8
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 28/92 (30%)
Query: 195 LPRDNWAPRKLWVSVLQGPLPAMRAGLWGLCRSLLIASVDSAPPREALGLGPEAGDPAFV 254
LP+ + APR ++V GP P++ PPR ALG P P F+
Sbjct: 364 LPQQS-APRTHLLTVSPGPAPSL-------------------PPRTALGPPPLQSRPGFL 403
Query: 255 QAPPALLGLLSKRIDGRIQLMAKEQVWGAREW 286
Q +S++ G +MA E+ G W
Sbjct: 404 Q--------VSRQRCGSAHVMAPEENAGTELW 427
>gi|169167316 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
Length = 542
Score = 29.3 bits (64), Expect = 5.8
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 28/92 (30%)
Query: 195 LPRDNWAPRKLWVSVLQGPLPAMRAGLWGLCRSLLIASVDSAPPREALGLGPEAGDPAFV 254
LP+ + APR ++V GP P++ PPR ALG P P F+
Sbjct: 364 LPQQS-APRTHLLTVSPGPAPSL-------------------PPRTALGPPPLQSRPGFL 403
Query: 255 QAPPALLGLLSKRIDGRIQLMAKEQVWGAREW 286
Q +S++ G +MA E+ G W
Sbjct: 404 Q--------VSRQRCGSAHVMAPEENAGTELW 427
>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
Length = 590
Score = 28.9 bits (63), Expect = 7.6
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 218 RAGLWGLCRSLLIASVDSAPPREALGLGPEAGDPAFVQ----APPALLGL 263
++GL+GL + VD +P ++ G PE GD +Q +PP G+
Sbjct: 42 KSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGV 91
>gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens]
Length = 499
Score = 28.9 bits (63), Expect = 7.6
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 218 RAGLWGLCRSLLIASVDSAPPREALGLGPEAGDPAFVQ----APPALLGL 263
++GL+GL + VD +P ++ G PE GD +Q +PP G+
Sbjct: 42 KSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGV 91
>gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
Length = 538
Score = 28.5 bits (62), Expect = 9.9
Identities = 17/47 (36%), Positives = 22/47 (46%)
Query: 212 GPLPAMRAGLWGLCRSLLIASVDSAPPREALGLGPEAGDPAFVQAPP 258
GPLPA+ A L L +L ++P GP G A +APP
Sbjct: 31 GPLPALLAHLRRLTGALTGGGGAASPGANGTRTGPAGGAGAAARAPP 77
>gi|194394139 notum pectinacetylesterase homolog [Homo sapiens]
Length = 496
Score = 28.5 bits (62), Expect = 9.9
Identities = 15/47 (31%), Positives = 22/47 (46%)
Query: 22 SPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRD 68
SP+ E G R + + C NC SRY T+R+ ++ RD
Sbjct: 105 SPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRD 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,483,633
Number of Sequences: 37866
Number of extensions: 669757
Number of successful extensions: 1720
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1701
Number of HSP's gapped (non-prelim): 18
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.