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Search of human proteins with 110815855
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
(380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 783 0.0
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 237 1e-62
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 219 2e-57
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 182 6e-46
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 167 2e-41
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 142 6e-34
gi|28373099 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 90 4e-18
gi|21264332 sialyltransferase 7A [Homo sapiens] 80 2e-15
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 79 9e-15
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 79 9e-15
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 75 1e-13
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 75 1e-13
gi|13569938 sialyltransferase 7E [Homo sapiens] 75 1e-13
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 74 2e-13
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 73 4e-13
gi|192448440 sialyltransferase 7B [Homo sapiens] 71 2e-12
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 68 2e-11
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 68 2e-11
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 62 7e-10
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 62 7e-10
gi|21361444 sialytransferase 7F [Homo sapiens] 62 1e-09
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 61 1e-09
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 59 7e-09
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 59 7e-09
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens] 56 5e-08
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 55 8e-08
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 55 1e-07
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 55 1e-07
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 55 1e-07
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 55 1e-07
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 783 bits (2022), Expect = 0.0
Identities = 380/380 (100%), Positives = 380/380 (100%)
Query: 1 MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR 60
MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR
Sbjct: 1 MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR 60
Query: 61 SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS 120
SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS
Sbjct: 61 SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS 120
Query: 121 VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI 180
VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI
Sbjct: 121 VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI 180
Query: 181 DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG 240
DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG
Sbjct: 181 DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG 240
Query: 241 AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS 300
AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS
Sbjct: 241 AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS 300
Query: 301 TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF 360
TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF
Sbjct: 301 TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF 360
Query: 361 QLLYRMHGEGLTKLTLSHCA 380
QLLYRMHGEGLTKLTLSHCA
Sbjct: 361 QLLYRMHGEGLTKLTLSHCA 380
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 237 bits (604), Expect = 1e-62
Identities = 121/312 (38%), Positives = 183/312 (58%), Gaps = 7/312 (2%)
Query: 70 PSFVPITN-SLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMH 128
P+ V +N S+ +Q SKW+ N+T L R++IL+ +D K+ S+ K +++ G ++H
Sbjct: 65 PAVVDRSNESIKHNIQPASSKWRHNQTLSLRIRKQILKFLDAEKDISVLKGTLKPGDIIH 124
Query: 129 YDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFR 188
Y + ++S N LLP SP+ NKH+ CA+VGNSG+L S CGQEID FV R
Sbjct: 125 YIFDRDS-TMNVSQNLYELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIR 183
Query: 189 CNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAF 248
CN AP + + RDVG KT+L T NPS++++ + +L+ R L L+G+ILWIPAF
Sbjct: 184 CNLAPVQEYARDVGLKTDLVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAF 243
Query: 249 FFHTSATVTRTLVDFFVEHRGQLKVQLAWPG-NIMQHVNRYWKNKHLSPKRLSTGILMYT 307
+ + ++H + V+ A+P ++ V YW + KR +TG+LMYT
Sbjct: 244 MARGGKERVEWVNELILKH--HVNVRTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYT 301
Query: 308 LASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMH 367
LA+ C++I+LYGFWPF D N + + YHYYD +T++ H +P EF+ L +H
Sbjct: 302 LATRFCKQIYLYGFWPFPLDQN-QNPVKYHYYDSLKYGYTSQ-ASPHTMPLEFKALKSLH 359
Query: 368 GEGLTKLTLSHC 379
+G KLT+ C
Sbjct: 360 EQGALKLTVGQC 371
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 219 bits (559), Expect = 2e-57
Identities = 116/297 (39%), Positives = 170/297 (57%), Gaps = 6/297 (2%)
Query: 84 QEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNN 143
Q WK N + L R+ IL+ +D ++ S+ K+S + G ++HY + +IS++
Sbjct: 65 QHNVEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRR-TLNISHD 123
Query: 144 FRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGR 203
SLLP+VSP+ N+ + CAVVGNSGIL S+CG+EID +FV RCN AP F DVG
Sbjct: 124 LHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGT 183
Query: 204 KTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDF 263
K++ T NPS++++ + DR F L L+ ++LWIPAF +
Sbjct: 184 KSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNAL 243
Query: 264 FVEHRGQLKVQLAWPG-NIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFW 322
++++ LKV+ A+P ++ V YW + KR STG+LMYTLA+ C+EIHLYGFW
Sbjct: 244 ILKNK--LKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFW 301
Query: 323 PFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHC 379
PF D N + + YHYYD ++ + H++P EF+ L +H G KLT C
Sbjct: 302 PFPKDLNGKA-VKYHYYDDLKYRYFSN-ASPHRMPLEFKTLNVLHNRGALKLTTGKC 356
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 182 bits (461), Expect = 6e-46
Identities = 106/294 (36%), Positives = 158/294 (53%), Gaps = 17/294 (5%)
Query: 90 WKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLP 149
WK + + R ++ D ++NF +++N+ +G M Y+ S K + I N + P
Sbjct: 115 WKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEI-PIKKNIFHMFP 173
Query: 150 DVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLT 208
P ++ YN CAVVGN GIL S CG EIDKSDFVFRCN PT +DVG KTNL
Sbjct: 174 VSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLV 233
Query: 209 TFNPSILEKYYNNLLTIQDRNNFFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEH 267
T NPSI+ Y NL +++ FL + A +PAF F + + + E
Sbjct: 234 TINPSIITLKYGNL---KEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES 290
Query: 268 RGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFD 327
+ + KV P ++ + +W+ K ++ RLSTG+++ ++A +C+ + LYGFWPF
Sbjct: 291 KARQKVLFFHP-KYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS-- 347
Query: 328 PNTREDLP--YHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHC 379
T ED+P +HYYD K K HQ+P E+ + ++H +G+ KL S C
Sbjct: 348 -KTVEDIPVSHHYYDNKLPK-----HGFHQMPKEYSQILQLHMKGILKLQFSKC 395
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 167 bits (422), Expect = 2e-41
Identities = 99/308 (32%), Positives = 165/308 (53%), Gaps = 12/308 (3%)
Query: 73 VPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYS 132
+P + Q + ++ + W+ N+TA R+++ D F++TK + +G+ M YD
Sbjct: 51 LPNEKEIVQGVLQQGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYD-G 109
Query: 133 SHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFA 192
Y F+I N+ SL P +P CAVVGN GIL S CG++ID+++FV RCN
Sbjct: 110 EFLYSFTIDNSTYSLFPQATPFQLP-LKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLP 168
Query: 193 PTEA-FQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFH 251
P + + +DVG K+ L T NPSI+ + + NLL R F ++K + + +++PAF
Sbjct: 169 PLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLW--SRKTFVDNMKIYNHSYIYMPAFSMK 226
Query: 252 TSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASA 311
T T V + + G + L N ++ + ++WK++ + KRLSTG+ + + A
Sbjct: 227 TG-TEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALG 285
Query: 312 ICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGL 371
+CEE+ +YGFWPF + + + + +HYYD + H +P EF L+ +H G
Sbjct: 286 LCEEVAIYGFWPFSVNMH-EQPISHHYYDN-----VLPFSGFHAMPEEFLQLWYLHKIGA 339
Query: 372 TKLTLSHC 379
++ L C
Sbjct: 340 LRMQLDPC 347
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 142 bits (357), Expect = 6e-34
Identities = 81/265 (30%), Positives = 141/265 (53%), Gaps = 11/265 (4%)
Query: 117 TKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQC 176
T+ + +G + Y+ + ++ I+ + P P + CAVVGN GIL S+C
Sbjct: 120 TQKNTPLGTKLKYEVDTSG-IYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRC 178
Query: 177 GQEIDKSDFVFRCNFAP-TEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSL 235
G+EI+ +DFVFRCN P +E + DVG KT++ T NPSI+ + ++ L + R F+ L
Sbjct: 179 GREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKL--EKWRRPFYRVL 236
Query: 236 KKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295
+ + A + +PA F++T T V + ++ + + + +V+RYW + +
Sbjct: 237 QVYENASVLLPA-FYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVR 295
Query: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQ 355
KR+STG+++ T A +CEE+HL+GFW F +P+ + +HYYD + H
Sbjct: 296 AKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLY-ITHHYYDNVKPR-----PGFHA 349
Query: 356 LPAEFQLLYRMHGEGLTKLTLSHCA 380
+P+E +H G+ ++ C+
Sbjct: 350 MPSEIFNFLHLHSRGILRVHTGTCS 374
>gi|28373099 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform b [Homo sapiens]
Length = 168
Score = 89.7 bits (221), Expect = 4e-18
Identities = 44/105 (41%), Positives = 66/105 (62%), Gaps = 1/105 (0%)
Query: 84 QEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNN 143
Q WK N + L R+ IL+ +D ++ S+ K+S + G ++HY + +IS++
Sbjct: 65 QHNVEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRR-TLNISHD 123
Query: 144 FRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFR 188
SLLP+VSP+ N+ + CAVVGNSGIL S+CG+EID +FV R
Sbjct: 124 LHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIR 168
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 80.5 bits (197), Expect = 2e-15
Identities = 72/241 (29%), Positives = 110/241 (45%), Gaps = 46/241 (19%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNN 221
CAVVGN GIL S GQEID D+VFR + A + +++DVG +T+ F L + +
Sbjct: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ---S 421
Query: 222 LLTIQDRNNFFLSLKK-------LDGA--ILWIPAFFFHTSATVTRTLVDFFVEHRGQ-- 270
LL + +R + L K L+G W+ A + +++ L F+ HR Q
Sbjct: 422 LLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMN-QTVMSKNL--FWFRHRPQEA 478
Query: 271 LKVQLAWPGNIMQHVN--RYWKNKHLSPKRL----------STGILMYTLASAICEEIHL 318
+ L ++ H + RY KN+ L K L +TG L+ A +C+++
Sbjct: 479 FREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSA 538
Query: 319 YGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQE-----SHQLPAEFQLLYRMHGEGLTK 373
YGF G E HYYD T W+ +H E ++ R+H EG+ +
Sbjct: 539 YGFITEG-----HERFSDHYYD-------TSWKRLIFYINHDFKLEREVWKRLHDEGIIR 586
Query: 374 L 374
L
Sbjct: 587 L 587
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 78.6 bits (192), Expect = 9e-15
Identities = 70/244 (28%), Positives = 109/244 (44%), Gaps = 27/244 (11%)
Query: 84 QEKPSKW---KFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSI 140
Q K S W +FN+T +Q + +N L ++ R + + + +I
Sbjct: 67 QRKLSAWFDERFNQT---------MQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTI 117
Query: 141 SNNFRSLLPDVSPIMNKHY---NICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAF 197
FR + +V P++ K CAVVGNSG L S G EID DFV R N APT F
Sbjct: 118 KELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGF 177
Query: 198 QRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVT 257
+ DVG KT P + +N+ I + K +D + W+ + T+ T++
Sbjct: 178 EADVGTKTTHHLVYPESFRELGDNVSMI------LVPFKTID--LEWVVSAI--TTGTIS 227
Query: 258 RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIH 317
T + + R + L + +++V W H + STGIL + +C+E+
Sbjct: 228 HTYIPVPAKIRVKQDKILIYHPAFIKYVFDNWLQGH--GRYPSTGILSVIFSMHVCDEVD 285
Query: 318 LYGF 321
LYGF
Sbjct: 286 LYGF 289
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 78.6 bits (192), Expect = 9e-15
Identities = 70/244 (28%), Positives = 109/244 (44%), Gaps = 27/244 (11%)
Query: 84 QEKPSKW---KFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSI 140
Q K S W +FN+T +Q + +N L ++ R + + + +I
Sbjct: 67 QRKLSAWFDERFNQT---------MQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTI 117
Query: 141 SNNFRSLLPDVSPIMNKHY---NICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAF 197
FR + +V P++ K CAVVGNSG L S G EID DFV R N APT F
Sbjct: 118 KELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGF 177
Query: 198 QRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVT 257
+ DVG KT P + +N+ I + K +D + W+ + T+ T++
Sbjct: 178 EADVGTKTTHHLVYPESFRELGDNVSMI------LVPFKTID--LEWVVSAI--TTGTIS 227
Query: 258 RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIH 317
T + + R + L + +++V W H + STGIL + +C+E+
Sbjct: 228 HTYIPVPAKIRVKQDKILIYHPAFIKYVFDNWLQGH--GRYPSTGILSVIFSMHVCDEVD 285
Query: 318 LYGF 321
LYGF
Sbjct: 286 LYGF 289
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 74.7 bits (182), Expect = 1e-13
Identities = 79/326 (24%), Positives = 136/326 (41%), Gaps = 31/326 (9%)
Query: 65 LKFLDPSFVPITNSLTQELQEKPSKWKFNRT--AFLHQRQEILQHVDVIKNFSLTKNSVR 122
+ ++DP V Q++ +K + KF +T A L + + VD++
Sbjct: 74 MHYVDPDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHR---YSVDLLPFVQKAPKDSE 130
Query: 123 IGQLMHYDYSSHKYVFSISNNFRSLLPD---VSPIMNKHYNICAVVGNSGILTGSQCGQE 179
+ K+ + LLP+ + K C V+G+ GIL G + G
Sbjct: 131 AESKYDPPFGFRKFSSKVQT-LLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHT 189
Query: 180 IDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNP-----SILEKYYNNL----LTIQDRNN 230
+++ D V R N AP E + VG KT + P S LE Y N+L L N
Sbjct: 190 LNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFN 249
Query: 231 FFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQH---VNR 287
+ ++ K + W+ FF+ A F + + A+ +I+Q+ +R
Sbjct: 250 WLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAF--DILQYSEPQSR 307
Query: 288 YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFT 347
+W P + G++ LA+ +C+E+ L G FG+D N + P HY+D +
Sbjct: 308 FWGRDKNVP---TIGVIAVVLATHLCDEVSLAG---FGYDLN-QPRTPLHYFDSQ-CMAA 359
Query: 348 TKWQESHQLPAEFQLLYRMHGEGLTK 373
+Q H + E + L ++ EG+ K
Sbjct: 360 MNFQTMHNVTTETKFLLKLVKEGVVK 385
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 74.7 bits (182), Expect = 1e-13
Identities = 79/326 (24%), Positives = 136/326 (41%), Gaps = 31/326 (9%)
Query: 65 LKFLDPSFVPITNSLTQELQEKPSKWKFNRT--AFLHQRQEILQHVDVIKNFSLTKNSVR 122
+ ++DP V Q++ +K + KF +T A L + + VD++
Sbjct: 97 MHYVDPDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHR---YSVDLLPFVQKAPKDSE 153
Query: 123 IGQLMHYDYSSHKYVFSISNNFRSLLPD---VSPIMNKHYNICAVVGNSGILTGSQCGQE 179
+ K+ + LLP+ + K C V+G+ GIL G + G
Sbjct: 154 AESKYDPPFGFRKFSSKVQT-LLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHT 212
Query: 180 IDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNP-----SILEKYYNNL----LTIQDRNN 230
+++ D V R N AP E + VG KT + P S LE Y N+L L N
Sbjct: 213 LNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFN 272
Query: 231 FFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQH---VNR 287
+ ++ K + W+ FF+ A F + + A+ +I+Q+ +R
Sbjct: 273 WLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAF--DILQYSEPQSR 330
Query: 288 YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFT 347
+W P + G++ LA+ +C+E+ L G FG+D N + P HY+D +
Sbjct: 331 FWGRDKNVP---TIGVIAVVLATHLCDEVSLAG---FGYDLN-QPRTPLHYFDSQ-CMAA 382
Query: 348 TKWQESHQLPAEFQLLYRMHGEGLTK 373
+Q H + E + L ++ EG+ K
Sbjct: 383 MNFQTMHNVTTETKFLLKLVKEGVVK 408
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 74.7 bits (182), Expect = 1e-13
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 29/203 (14%)
Query: 155 MNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSI 214
+ H CA+V +SG L S+ G +ID+++ V R N APT + RDVG +T+L S
Sbjct: 89 LKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSS 148
Query: 215 LEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFF------------FHTSATVTRTLVD 262
+++ N + L++ + I W P+ + H + V L
Sbjct: 149 IQRILRN-------RHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKA 201
Query: 263 FFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFW 322
F + L+ + K++ +S LSTG T+A +C+ I++YG
Sbjct: 202 FMITRHKMLQFDELFK-------QETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMV 254
Query: 323 PFGF--DPNTREDLPYHYYDKKG 343
P F DPN +PYHYY+ G
Sbjct: 255 PPDFCRDPN-HPSVPYHYYEPFG 276
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 74.3 bits (181), Expect = 2e-13
Identities = 63/205 (30%), Positives = 93/205 (45%), Gaps = 19/205 (9%)
Query: 146 SLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKT 205
S +PD P++ + CAVV +SG + GS G EID ++ VFR N APT F+ DVG+++
Sbjct: 60 SSVPDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRS 119
Query: 206 NLT----TFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTL- 260
L T P +L Y + +D + +L + T +TR
Sbjct: 120 TLRVVSHTSVPLLLRNYSHYFQKARDTLYMVWGQGRHMDRVL--GGRTYRTLLQLTRMYP 177
Query: 261 ---VDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIH 317
V F E +A+ I Q + KN+ S LSTG LA +CEEI
Sbjct: 178 GLQVYTFTER------MMAYCDQIFQ--DETGKNRRQSGSFLSTGWFTMILALELCEEIV 229
Query: 318 LYGFWPFGF-DPNTREDLPYHYYDK 341
+YG + + +PYHY++K
Sbjct: 230 VYGMVSDSYCREKSHPSVPYHYFEK 254
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 73.2 bits (178), Expect = 4e-13
Identities = 52/160 (32%), Positives = 80/160 (50%), Gaps = 12/160 (7%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNN 221
CAVVGNSG L GS GQ++D +F+ R N APT F++DVG +T P + N
Sbjct: 152 CAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHHFMYPESAKNLPAN 211
Query: 222 LLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNI 281
+ + + K LD +LWI + T V F+ + KVQ+ P
Sbjct: 212 VSFV------LVPFKVLD--LLWIASALSTGQIRFTYAPVKSFLRVDKE-KVQIYNPA-F 261
Query: 282 MQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGF 321
++++ W H + STG+L+ A +C+E+++YGF
Sbjct: 262 FKYIHDRWTEHH--GRYPSTGMLVLFFALHVCDEVNVYGF 299
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 70.9 bits (172), Expect = 2e-12
Identities = 69/236 (29%), Positives = 97/236 (41%), Gaps = 38/236 (16%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILE----K 217
CAVVGN GIL GS+ G ID D+VFR N A + F+RDVG KT+ F + ++
Sbjct: 151 CAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVS 210
Query: 218 YYNNLLTI----QDRNNFFL-----SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHR 268
Y+N T QD F+ L AIL +P +F
Sbjct: 211 YWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHA---YFGPEA 267
Query: 269 GQLKVQLAWPGNIMQHVNRYWKNKHLSPK-----RLSTGILMYTLASAICEEIHLYGF-- 321
K +L P I R+ K+K ++ STG LM A C+++ YGF
Sbjct: 268 SASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFIT 327
Query: 322 ---WPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKL 374
W F HY+++K + +H L E L +H G+ +L
Sbjct: 328 SNYWKFS----------DHYFERKMKPLI--FYANHDLSLEAALWRDLHKAGILQL 371
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 67.8 bits (164), Expect = 2e-11
Identities = 56/192 (29%), Positives = 90/192 (46%), Gaps = 34/192 (17%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSIL--EK-- 217
CAVV ++G L SQ G+EID D V R N APT FQ+DVG KT + N ++ EK
Sbjct: 184 CAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRF 243
Query: 218 -----YYNNLLTIQDRNNFFLSLKKLDGAILWI--PAFFFHTSATVTRTL---VDFFVEH 267
Y +L + D + + + K W P + F + R L F++
Sbjct: 244 LKDSLYNEGILIVWDPSVYHSDIPK------WYQNPDYNFFNNYKTYRKLHPNQPFYI-- 295
Query: 268 RGQLKVQLAWP-GNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGF 326
LK Q+ W +I+Q ++ + + P S+G+L + +C+++ +Y F P
Sbjct: 296 ---LKPQMPWELWDILQEIS----PEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLP--- 345
Query: 327 DPNTREDLPYHY 338
+ D+ Y+Y
Sbjct: 346 -SKRKTDVCYYY 356
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 67.8 bits (164), Expect = 2e-11
Identities = 56/192 (29%), Positives = 90/192 (46%), Gaps = 34/192 (17%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSIL--EK-- 217
CAVV ++G L SQ G+EID D V R N APT FQ+DVG KT + N ++ EK
Sbjct: 184 CAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRF 243
Query: 218 -----YYNNLLTIQDRNNFFLSLKKLDGAILWI--PAFFFHTSATVTRTL---VDFFVEH 267
Y +L + D + + + K W P + F + R L F++
Sbjct: 244 LKDSLYNEGILIVWDPSVYHSDIPK------WYQNPDYNFFNNYKTYRKLHPNQPFYI-- 295
Query: 268 RGQLKVQLAWP-GNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGF 326
LK Q+ W +I+Q ++ + + P S+G+L + +C+++ +Y F P
Sbjct: 296 ---LKPQMPWELWDILQEIS----PEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLP--- 345
Query: 327 DPNTREDLPYHY 338
+ D+ Y+Y
Sbjct: 346 -SKRKTDVCYYY 356
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 62.4 bits (150), Expect = 7e-10
Identities = 58/212 (27%), Positives = 96/212 (45%), Gaps = 32/212 (15%)
Query: 144 FRSLLPDVSPIMNKH---YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRD 200
+R L+P V P+ H CAVV ++G + S G+EID D V R N APT +++D
Sbjct: 276 WRRLVPAV-PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKD 334
Query: 201 VGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVT--- 257
VG KT + N IL ++ + SL K + W PA + SA +
Sbjct: 335 VGNKTTIRIINSQILTNPSHHFID--------SSLYKDVILVAWDPAPY---SANLNLWY 383
Query: 258 ----RTLVDFFVEHRGQLKVQ---LAWPGNIMQHVNRYWKN--KHLSPKRLSTGILMYTL 308
L +++HR + Q + P I Q + +N + + P S+G + +
Sbjct: 384 KKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILI 443
Query: 309 ASAICEEIHLYGFWPFGFDPNTREDLPYHYYD 340
++C E+H+Y + P+ R+ HY++
Sbjct: 444 MMSMCREVHVY-----EYIPSVRQTELCHYHE 470
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 62.4 bits (150), Expect = 7e-10
Identities = 58/212 (27%), Positives = 96/212 (45%), Gaps = 32/212 (15%)
Query: 144 FRSLLPDVSPIMNKH---YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRD 200
+R L+P V P+ H CAVV ++G + S G+EID D V R N APT +++D
Sbjct: 276 WRRLVPAV-PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKD 334
Query: 201 VGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVT--- 257
VG KT + N IL ++ + SL K + W PA + SA +
Sbjct: 335 VGNKTTIRIINSQILTNPSHHFID--------SSLYKDVILVAWDPAPY---SANLNLWY 383
Query: 258 ----RTLVDFFVEHRGQLKVQ---LAWPGNIMQHVNRYWKN--KHLSPKRLSTGILMYTL 308
L +++HR + Q + P I Q + +N + + P S+G + +
Sbjct: 384 KKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILI 443
Query: 309 ASAICEEIHLYGFWPFGFDPNTREDLPYHYYD 340
++C E+H+Y + P+ R+ HY++
Sbjct: 444 MMSMCREVHVY-----EYIPSVRQTELCHYHE 470
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 61.6 bits (148), Expect = 1e-09
Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 23/193 (11%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNN 221
C +V +S L G++ G EI++++ R N APT + DVG KT +++
Sbjct: 108 CVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVV-------AHSS 160
Query: 222 LLTIQDRNNFFLSLKKLDGAILW-IPAFFFHTSATVTRTLVDFFVEHRG----QLKVQLA 276
+ + R F++ I W P+ ++ R ++ G ++
Sbjct: 161 VFRVLRRPQEFVNRTPETVFIFWGPPSKMQKPQGSLVRV-----IQRAGLVFPNMEAYAV 215
Query: 277 WPGNIMQHVNRY----WKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGF--DPNT 330
PG + Q + + K++ S LSTG +A +C+ +H+YG P +
Sbjct: 216 SPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPR 275
Query: 331 REDLPYHYYDKKG 343
+ +PYHYY+ KG
Sbjct: 276 LQRMPYHYYEPKG 288
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 61.2 bits (147), Expect = 1e-09
Identities = 55/203 (27%), Positives = 84/203 (41%), Gaps = 43/203 (21%)
Query: 160 NICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTF--------- 210
++CA+V NSG + G + G EID+S ++R N APT+ ++ DVGR T +
Sbjct: 78 DLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLL 137
Query: 211 -NPSILEKYYNNLLTI---------QDRNNF-FLSLKKLDGAILWIPAFFFHTSATVTRT 259
NP K N + + +D N + LKK G ++ A + T+
Sbjct: 138 KNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVG--IYPNAQIYVTTEKRMSY 195
Query: 260 LVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLY 319
F + G+ +VQ S LSTG + LA C IH+Y
Sbjct: 196 CDGVFKKETGKDRVQ--------------------SGSYLSTGWFTFLLAMDACYGIHVY 235
Query: 320 GFWPFGF-DPNTREDLPYHYYDK 341
G + +PYHYY++
Sbjct: 236 GMINDTYCKTEGYRKVPYHYYEQ 258
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 58.9 bits (141), Expect = 7e-09
Identities = 58/212 (27%), Positives = 88/212 (41%), Gaps = 31/212 (14%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNP-SILEKYYN 220
C VVGN G+L G++ID D + R N P + +VGR+T F P S+ +
Sbjct: 118 CVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIH 177
Query: 221 N------LLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTR-----TLVDFFVEHRG 269
N +LT ++ L+ L G + F+ + + ++D F+
Sbjct: 178 NDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTA 237
Query: 270 QLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPN 329
+ + H + + K+ PK +TGI+ TLA IC E+HL GF + F
Sbjct: 238 AYE---------LLHFPKVFP-KNQKPKHPTTGIIAITLAFYICHEVHLAGF-KYNF--- 283
Query: 330 TREDL--PYHYYDKKGTKFTTKWQESHQLPAE 359
DL P HYY K H + AE
Sbjct: 284 --SDLKSPLHYYGNATMSLMNK-NAYHNVTAE 312
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 58.9 bits (141), Expect = 7e-09
Identities = 57/196 (29%), Positives = 78/196 (39%), Gaps = 33/196 (16%)
Query: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILE---KY 218
C VVGN L S G I+K D V R N AP ++ DVG KT + F P K
Sbjct: 116 CVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFDPKV 175
Query: 219 YNNLLTIQDRNNF----------FLSLKKLDGAILW-IPAFFFHTSATVTRTLVDFFVEH 267
NN T+ F LS KK W P + + R L FF+E
Sbjct: 176 ENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEI 235
Query: 268 RGQ--LKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFG 325
L + + P I Q + +TG+L TLA +C+ +H+ G FG
Sbjct: 236 AADKLLSLPMQQPRKIKQ--------------KPTTGLLAITLALHLCDLVHIAG---FG 278
Query: 326 FDPNTREDLPYHYYDK 341
+ + HYY++
Sbjct: 279 YPDAYNKKQTIHYYEQ 294
>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
Length = 218
Score = 56.2 bits (134), Expect = 5e-08
Identities = 53/180 (29%), Positives = 78/180 (43%), Gaps = 19/180 (10%)
Query: 171 LTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLT----TFNPSILEKYYNNLLTIQ 226
+ GS G EID ++ VFR N APT F+ DVG+++ L T P +L Y + +
Sbjct: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKAR 60
Query: 227 DRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTL----VDFFVEHRGQLKVQLAWPGNIM 282
D + +L + T +TR V F E +A+ I
Sbjct: 61 DTLYMVWGQGRHMDRVL--GGRTYRTLLQLTRMYPGLQVYTFTER------MMAYCDQIF 112
Query: 283 QHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGF-DPNTREDLPYHYYDK 341
Q + KN+ S LSTG LA +CEEI +YG + + +PYHY++K
Sbjct: 113 Q--DETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFEK 170
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 55.5 bits (132), Expect = 8e-08
Identities = 31/75 (41%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 144 FRSLLPDVSPIMNKH---YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRD 200
+R L+P V P+ H CAVV ++G + S G+EID D V R N APT +++D
Sbjct: 276 WRRLVPAV-PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKD 334
Query: 201 VGRKTNLTTFNPSIL 215
VG KT + N IL
Sbjct: 335 VGNKTTIRIINSQIL 349
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)
Query: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194
K + S++ +R L P + + + C +VGN G+L G ID D V R N AP
Sbjct: 175 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 230
Query: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253
+ F++DVG KT L T+ +++ +R++ F+ W+ +
Sbjct: 231 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 285
Query: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295
+ + R L +F++ + L + +M N
Sbjct: 286 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 336
Query: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354
+ G + T+A C+E+ + G FG+D +T + P HYY+ + W +
Sbjct: 337 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 390
Query: 355 QLPAEF 360
Q EF
Sbjct: 391 QREKEF 396
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)
Query: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194
K + S++ +R L P + + + C +VGN G+L G ID D V R N AP
Sbjct: 121 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 176
Query: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253
+ F++DVG KT L T+ +++ +R++ F+ W+ +
Sbjct: 177 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 231
Query: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295
+ + R L +F++ + L + +M N
Sbjct: 232 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 282
Query: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354
+ G + T+A C+E+ + G FG+D +T + P HYY+ + W +
Sbjct: 283 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 336
Query: 355 QLPAEF 360
Q EF
Sbjct: 337 QREKEF 342
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)
Query: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194
K + S++ +R L P + + + C +VGN G+L G ID D V R N AP
Sbjct: 191 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 246
Query: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253
+ F++DVG KT L T+ +++ +R++ F+ W+ +
Sbjct: 247 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 301
Query: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295
+ + R L +F++ + L + +M N
Sbjct: 302 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 352
Query: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354
+ G + T+A C+E+ + G FG+D +T + P HYY+ + W +
Sbjct: 353 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 406
Query: 355 QLPAEF 360
Q EF
Sbjct: 407 QREKEF 412
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/246 (22%), Positives = 97/246 (39%), Gaps = 44/246 (17%)
Query: 135 KYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPT 194
K + S++ +R L P + + + C +VGN G+L G ID D V R N AP
Sbjct: 152 KAILSVTKEYR-LTPALDSLRCRR---CIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPV 207
Query: 195 EAFQRDVGRKTNL-TTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTS 253
+ F++DVG KT L T+ +++ +R++ F+ W+ +
Sbjct: 208 KGFEKDVGSKTTLRITYPEGAMQRPEQ-----YERDSLFVLAGFKWQDFKWLKYIVYKER 262
Query: 254 ATVT------------------RTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLS 295
+ + R L +F++ + L + +M N
Sbjct: 263 VSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGN--------- 313
Query: 296 PKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDK-KGTKFTTKWQESH 354
+ G + T+A C+E+ + G FG+D +T + P HYY+ + W +
Sbjct: 314 --IPTLGSVAVTMALHGCDEVAVAG---FGYDMST-PNAPLHYYETVRMAAIKESWTHNI 367
Query: 355 QLPAEF 360
Q EF
Sbjct: 368 QREKEF 373
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,243,259
Number of Sequences: 37866
Number of extensions: 614138
Number of successful extensions: 1764
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1683
Number of HSP's gapped (non-prelim): 48
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.