Search of human proteins with 169171552

Search of human proteins with 169171552

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169171552 PREDICTED: similar to homeodomain interacting
protein kinase 3 [Homo sapiens]
         (264 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169171552 PREDICTED: similar to homeodomain interacting prote...   509   e-144
gi|164420691 homeodomain interacting protein kinase 2 isoform 2 ...   502   e-142
gi|164420685 homeodomain interacting protein kinase 2 isoform 1 ...   502   e-142
gi|169171014 PREDICTED: similar to homeodomain interacting prote...   502   e-142
gi|38201640 homeodomain-interacting protein kinase 1 isoform 1 [...   293   1e-79
gi|38201638 homeodomain-interacting protein kinase 1 isoform 2 [...   293   1e-79
gi|114796630 homeodomain interacting protein kinase 3 isoform 2 ...   228   5e-60
gi|114796624 homeodomain interacting protein kinase 3 isoform 1 ...   228   5e-60
gi|28827774 dual-specificity tyrosine-(Y)-phosphorylation regula...    62   5e-10
gi|31542768 homeodomain interacting protein kinase 4 [Homo sapiens]    56   4e-08
gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat...    55   8e-08
gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat...    55   8e-08
gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat...    55   8e-08
gi|153281169 dual-specificity tyrosine-(Y)-phosphorylation regul...    55   8e-08
gi|4503427 dual-specificity tyrosine-(Y)-phosphorylation regulat...    55   8e-08
gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regula...    53   2e-07
gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regula...    53   2e-07
gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regula...    53   2e-07
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula...    53   2e-07
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula...    53   2e-07
gi|47717134 CDC-like kinase 2 [Homo sapiens]                           50   3e-06
gi|51702242 dual-specificity tyrosine-(Y)-phosphorylation regula...    47   2e-05
gi|51702240 dual-specificity tyrosine-(Y)-phosphorylation regula...    47   2e-05
gi|194097436 CDC-like kinase 3 isoform a [Homo sapiens]                45   5e-05
gi|153791372 CDC-like kinase 3 isoform b [Homo sapiens]                45   5e-05
gi|10190706 CDC-like kinase 4 [Homo sapiens]                           44   1e-04
gi|241666392 CDC-like kinase 1 isoform 2 [Homo sapiens]                43   2e-04
gi|67551261 CDC-like kinase 1 isoform 1 [Homo sapiens]                 43   2e-04
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]                    42   7e-04
gi|4758128 doublecortin-like kinase 1 [Homo sapiens]                   41   0.001

>gi|169171552 PREDICTED: similar to homeodomain interacting protein
           kinase 3 [Homo sapiens]
          Length = 264

 Score =  509 bits (1310), Expect = e-144
 Identities = 264/264 (100%), Positives = 264/264 (100%)

Query: 1   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 60
           MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV
Sbjct: 1   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 60

Query: 61  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 120
           STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ
Sbjct: 61  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 120

Query: 121 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 180
           KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV
Sbjct: 121 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 180

Query: 181 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 240
           QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL
Sbjct: 181 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 240

Query: 241 ARLSTESADDYNXXXXXXXQFSSR 264
           ARLSTESADDYN       QFSSR
Sbjct: 241 ARLSTESADDYNXXXXXXXQFSSR 264


>gi|164420691 homeodomain interacting protein kinase 2 isoform 2
           [Homo sapiens]
          Length = 1171

 Score =  502 bits (1293), Expect = e-142
 Identities = 252/252 (100%), Positives = 252/252 (100%)

Query: 1   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 60
           MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV
Sbjct: 8   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 67

Query: 61  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 120
           STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ
Sbjct: 68  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 127

Query: 121 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 180
           KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV
Sbjct: 128 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 187

Query: 181 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 240
           QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL
Sbjct: 188 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 247

Query: 241 ARLSTESADDYN 252
           ARLSTESADDYN
Sbjct: 248 ARLSTESADDYN 259


>gi|164420685 homeodomain interacting protein kinase 2 isoform 1
           [Homo sapiens]
          Length = 1198

 Score =  502 bits (1293), Expect = e-142
 Identities = 252/252 (100%), Positives = 252/252 (100%)

Query: 1   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 60
           MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV
Sbjct: 8   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 67

Query: 61  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 120
           STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ
Sbjct: 68  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 127

Query: 121 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 180
           KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV
Sbjct: 128 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 187

Query: 181 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 240
           QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL
Sbjct: 188 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 247

Query: 241 ARLSTESADDYN 252
           ARLSTESADDYN
Sbjct: 248 ARLSTESADDYN 259


>gi|169171014 PREDICTED: similar to homeodomain interacting protein
           kinase 2 [Homo sapiens]
          Length = 460

 Score =  502 bits (1293), Expect = e-142
 Identities = 252/252 (100%), Positives = 252/252 (100%)

Query: 1   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 60
           MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV
Sbjct: 8   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 67

Query: 61  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 120
           STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ
Sbjct: 68  STSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQ 127

Query: 121 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 180
           KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV
Sbjct: 128 KCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLV 187

Query: 181 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 240
           QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL
Sbjct: 188 QHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSIL 247

Query: 241 ARLSTESADDYN 252
           ARLSTESADDYN
Sbjct: 248 ARLSTESADDYN 259


>gi|38201640 homeodomain-interacting protein kinase 1 isoform 1
           [Homo sapiens]
          Length = 1210

 Score =  293 bits (749), Expect = 1e-79
 Identities = 157/255 (61%), Positives = 192/255 (75%), Gaps = 8/255 (3%)

Query: 1   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 60
           MAS +QVFSP ++ SSAFCS KKLKIEPS  WD++G  S+ K Y+ SK +P +Q      
Sbjct: 1   MASQLQVFSPPSVSSSAFCSAKKLKIEPSG-WDVSGQSSNDKYYTHSKTLPATQGQA--- 56

Query: 61  STSLPVPNPSLP-YEQTIVFPG-STGHIVVTSA-SSTSVTGQVLGGPHNLMRRSTVSLLD 117
           ++S  V N ++P Y+Q ++ P  +  HIVVT+A SS S           L  RS VSLL+
Sbjct: 57  NSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHRSNVSLLE 116

Query: 118 TYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDY 177
            YQKCGLKRKSEE+++  SVQIIEEHPP++  N +    A ATT+T T+K+S S+ EGDY
Sbjct: 117 PYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRT-VVGAAATTTTVTTKSSSSSGEGDY 175

Query: 178 QLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEV 237
           QLVQHE+LCSMTN+YEVLEFLGRGTFGQV KCWKR T EIVAIKILKNHPSYARQGQIEV
Sbjct: 176 QLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEV 235

Query: 238 SILARLSTESADDYN 252
           SIL+RLS+E+AD+YN
Sbjct: 236 SILSRLSSENADEYN 250


>gi|38201638 homeodomain-interacting protein kinase 1 isoform 2
           [Homo sapiens]
          Length = 1075

 Score =  293 bits (749), Expect = 1e-79
 Identities = 157/255 (61%), Positives = 192/255 (75%), Gaps = 8/255 (3%)

Query: 1   MASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTV 60
           MAS +QVFSP ++ SSAFCS KKLKIEPS  WD++G  S+ K Y+ SK +P +Q      
Sbjct: 1   MASQLQVFSPPSVSSSAFCSAKKLKIEPSG-WDVSGQSSNDKYYTHSKTLPATQGQA--- 56

Query: 61  STSLPVPNPSLP-YEQTIVFPG-STGHIVVTSA-SSTSVTGQVLGGPHNLMRRSTVSLLD 117
           ++S  V N ++P Y+Q ++ P  +  HIVVT+A SS S           L  RS VSLL+
Sbjct: 57  NSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHRSNVSLLE 116

Query: 118 TYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDY 177
            YQKCGLKRKSEE+++  SVQIIEEHPP++  N +    A ATT+T T+K+S S+ EGDY
Sbjct: 117 PYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRT-VVGAAATTTTVTTKSSSSSGEGDY 175

Query: 178 QLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEV 237
           QLVQHE+LCSMTN+YEVLEFLGRGTFGQV KCWKR T EIVAIKILKNHPSYARQGQIEV
Sbjct: 176 QLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEV 235

Query: 238 SILARLSTESADDYN 252
           SIL+RLS+E+AD+YN
Sbjct: 236 SILSRLSSENADEYN 250


>gi|114796630 homeodomain interacting protein kinase 3 isoform 2
           [Homo sapiens]
          Length = 1194

 Score =  228 bits (580), Expect = 5e-60
 Identities = 143/266 (53%), Positives = 172/266 (64%), Gaps = 23/266 (8%)

Query: 1   MASHVQVFSPHTLQ--SSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPAT- 57
           MAS V V+ P+  Q  SSAFCSVKKLK+EPSS   +    ++ + Y   +N   S P T 
Sbjct: 1   MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSC--VFQERNYPRTYVNGRNFGNSHPPTK 58

Query: 58  -TTVSTSLPVPNP-----SLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRS 111
            +   T +P   P     SL     +V   + G   V +A +     Q    P     R+
Sbjct: 59  GSAFQTKIPFNRPRGHNFSLQ-TSAVVLKNTAGATKVIAAQAQQAHVQA---PQIGAWRN 114

Query: 112 TVSLLDTYQKCGLKRKSEEIENTSS-VQIIEEH---PPMIQNNASG-ATVATATTSTATS 166
            +  L+  Q+CGLKRKSEE++N SS +QI++E    P M+Q N     TV TATT    S
Sbjct: 115 RLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTG---S 171

Query: 167 KNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNH 226
           K + +  EGDYQLVQHEVLCSM NTYEVL+FLGRGTFGQVVKCWKRGTNEIVAIKILKNH
Sbjct: 172 KQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNH 231

Query: 227 PSYARQGQIEVSILARLSTESADDYN 252
           PSYARQGQIEVSILARLSTE+AD+YN
Sbjct: 232 PSYARQGQIEVSILARLSTENADEYN 257


>gi|114796624 homeodomain interacting protein kinase 3 isoform 1
           [Homo sapiens]
          Length = 1215

 Score =  228 bits (580), Expect = 5e-60
 Identities = 143/266 (53%), Positives = 172/266 (64%), Gaps = 23/266 (8%)

Query: 1   MASHVQVFSPHTLQ--SSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPAT- 57
           MAS V V+ P+  Q  SSAFCSVKKLK+EPSS   +    ++ + Y   +N   S P T 
Sbjct: 1   MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSC--VFQERNYPRTYVNGRNFGNSHPPTK 58

Query: 58  -TTVSTSLPVPNP-----SLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRS 111
            +   T +P   P     SL     +V   + G   V +A +     Q    P     R+
Sbjct: 59  GSAFQTKIPFNRPRGHNFSLQ-TSAVVLKNTAGATKVIAAQAQQAHVQA---PQIGAWRN 114

Query: 112 TVSLLDTYQKCGLKRKSEEIENTSS-VQIIEEH---PPMIQNNASG-ATVATATTSTATS 166
            +  L+  Q+CGLKRKSEE++N SS +QI++E    P M+Q N     TV TATT    S
Sbjct: 115 RLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTG---S 171

Query: 167 KNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNH 226
           K + +  EGDYQLVQHEVLCSM NTYEVL+FLGRGTFGQVVKCWKRGTNEIVAIKILKNH
Sbjct: 172 KQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNH 231

Query: 227 PSYARQGQIEVSILARLSTESADDYN 252
           PSYARQGQIEVSILARLSTE+AD+YN
Sbjct: 232 PSYARQGQIEVSILARLSTENADEYN 257


>gi|28827774 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 4 [Homo sapiens]
          Length = 520

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 35/88 (39%), Positives = 51/88 (57%), Gaps = 4/88 (4%)

Query: 166 SKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKN 225
           SK S  +  G Y  V H+    +   YEVLE +G+G+FGQV KC     NE+VA+KI++N
Sbjct: 81  SKTSFDDEHGFYLKVLHD---HIAYRYEVLETIGKGSFGQVAKCLDHKNNELVALKIIRN 137

Query: 226 HPSYARQGQIEVSILARLSTESADD-YN 252
              + +Q  +E+ IL  L  +  D+ YN
Sbjct: 138 KKRFHQQALMELKILEALRKKDKDNTYN 165


>gi|31542768 homeodomain interacting protein kinase 4 [Homo sapiens]
          Length = 616

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 24/39 (61%), Positives = 32/39 (82%)

Query: 187 SMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKN 225
           S T+ Y+++E LG+GTFG+V K W+R T E+VAIKILKN
Sbjct: 6   SETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKN 44


>gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform a [Homo sapiens]
          Length = 629

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 24/58 (41%), Positives = 38/58 (65%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK +   T E+VAIKI+KN  ++  Q QIE+ +L  ++    +
Sbjct: 111 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTE 168


>gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform c [Homo sapiens]
          Length = 601

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 24/58 (41%), Positives = 38/58 (65%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK +   T E+VAIKI+KN  ++  Q QIE+ +L  ++    +
Sbjct: 111 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTE 168


>gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform b [Homo sapiens]
          Length = 589

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 24/58 (41%), Positives = 38/58 (65%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK +   T E+VAIKI+KN  ++  Q QIE+ +L  ++    +
Sbjct: 111 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTE 168


>gi|153281169 dual-specificity tyrosine-(Y)-phosphorylation
           regulated kinase 2 isoform 2 [Homo sapiens]
          Length = 601

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 30/89 (33%), Positives = 49/89 (55%), Gaps = 4/89 (4%)

Query: 163 TATSKNSG-SNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIK 221
           T    N G  + +G Y  V H+    +   YEVL+ +G+G+FGQVVK +    ++ VA+K
Sbjct: 195 TGGPNNGGYDDDQGSYVQVPHD---HVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALK 251

Query: 222 ILKNHPSYARQGQIEVSILARLSTESADD 250
           +++N   + RQ   E+ IL  L  +  D+
Sbjct: 252 MVRNEKRFHRQAAEEIRILEHLRKQDKDN 280


>gi|4503427 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 2 isoform 1 [Homo sapiens]
          Length = 528

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 30/89 (33%), Positives = 49/89 (55%), Gaps = 4/89 (4%)

Query: 163 TATSKNSG-SNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIK 221
           T    N G  + +G Y  V H+    +   YEVL+ +G+G+FGQVVK +    ++ VA+K
Sbjct: 122 TGGPNNGGYDDDQGSYVQVPHD---HVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALK 178

Query: 222 ILKNHPSYARQGQIEVSILARLSTESADD 250
           +++N   + RQ   E+ IL  L  +  D+
Sbjct: 179 MVRNEKRFHRQAAEEIRILEHLRKQDKDN 207


>gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 5 [Homo sapiens]
          Length = 529

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 25/58 (43%), Positives = 37/58 (63%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK + R   E VAIKI+KN  ++  Q QIEV +L  ++    +
Sbjct: 159 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTE 216


>gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 4 [Homo sapiens]
          Length = 540

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 25/58 (43%), Positives = 37/58 (63%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK + R   E VAIKI+KN  ++  Q QIEV +L  ++    +
Sbjct: 159 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTE 216


>gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 3 [Homo sapiens]
          Length = 584

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 25/58 (43%), Positives = 37/58 (63%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK + R   E VAIKI+KN  ++  Q QIEV +L  ++    +
Sbjct: 159 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTE 216



 Score = 28.5 bits (62), Expect = 6.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 125 KRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQH 182
           K+ ++E  NTS+   +   P M Q+ +SG T +T+++S  +S  S S         QH
Sbjct: 480 KKTADEGTNTSNS--VSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQH 535


>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 2 [Homo sapiens]
          Length = 754

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 25/58 (43%), Positives = 37/58 (63%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK + R   E VAIKI+KN  ++  Q QIEV +L  ++    +
Sbjct: 150 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTE 207



 Score = 28.5 bits (62), Expect = 6.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 125 KRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQH 182
           K+ ++E  NTS+   +   P M Q+ +SG T +T+++S  +S  S S         QH
Sbjct: 471 KKTADEGTNTSNS--VSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQH 526


>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 1 [Homo sapiens]
          Length = 763

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 25/58 (43%), Positives = 37/58 (63%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESAD 249
           YE+   +G+G+FGQVVK + R   E VAIKI+KN  ++  Q QIEV +L  ++    +
Sbjct: 159 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTE 216



 Score = 28.5 bits (62), Expect = 6.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 125 KRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQH 182
           K+ ++E  NTS+   +   P M Q+ +SG T +T+++S  +S  S S         QH
Sbjct: 480 KKTADEGTNTSNS--VSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQH 535


>gi|47717134 CDC-like kinase 2 [Homo sapiens]
          Length = 498

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 31/97 (31%), Positives = 58/97 (59%), Gaps = 6/97 (6%)

Query: 158 TATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKC--WKRGTN 215
           +++ S+  +K+   ++EG   L+ H V   +   YE++  LG GTFG+VV+C   +RG  
Sbjct: 131 SSSHSSRRAKSVEDDAEG--HLIYH-VGDWLQERYEIVSTLGEGTFGRVVQCVDHRRG-G 186

Query: 216 EIVAIKILKNHPSYARQGQIEVSILARLSTESADDYN 252
             VA+KI+KN   Y    ++E+++L +++ +  D+ N
Sbjct: 187 ARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKN 223


>gi|51702242 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 3 isoform b [Homo sapiens]
          Length = 568

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 1/79 (1%)

Query: 168 NSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHP 227
           N+G   + D   + H     +   YEVL+ +G+G+FGQV + +     + VA+K+++N  
Sbjct: 166 NNGGYDDADGAYI-HVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEK 224

Query: 228 SYARQGQIEVSILARLSTE 246
            + RQ   E+ IL  L  +
Sbjct: 225 RFHRQAAEEIRILEHLKKQ 243


>gi|51702240 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 3 isoform a [Homo sapiens]
          Length = 588

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 1/79 (1%)

Query: 168 NSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHP 227
           N+G   + D   + H     +   YEVL+ +G+G+FGQV + +     + VA+K+++N  
Sbjct: 186 NNGGYDDADGAYI-HVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEK 244

Query: 228 SYARQGQIEVSILARLSTE 246
            + RQ   E+ IL  L  +
Sbjct: 245 RFHRQAAEEIRILEHLKKQ 263


>gi|194097436 CDC-like kinase 3 isoform a [Homo sapiens]
          Length = 638

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 28/100 (28%), Positives = 56/100 (56%), Gaps = 10/100 (10%)

Query: 157 ATATTSTATSKNSGSNSEGDYQLVQHEVLCS----MTNTYEVLEFLGRGTFGQVVKC--W 210
           + ++ S  +SK S  + E D +     ++C     +   YE++  LG GTFG+VV+C   
Sbjct: 268 SASSRSQQSSKRSSRSVEDDKE---GHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDH 324

Query: 211 KRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADD 250
            RG ++ VA+KI++N   Y    ++E+++L ++  +  ++
Sbjct: 325 ARGKSQ-VALKIIRNVGKYREAARLEINVLKKIKEKDKEN 363


>gi|153791372 CDC-like kinase 3 isoform b [Homo sapiens]
          Length = 490

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 28/100 (28%), Positives = 56/100 (56%), Gaps = 10/100 (10%)

Query: 157 ATATTSTATSKNSGSNSEGDYQLVQHEVLCS----MTNTYEVLEFLGRGTFGQVVKC--W 210
           + ++ S  +SK S  + E D +     ++C     +   YE++  LG GTFG+VV+C   
Sbjct: 120 SASSRSQQSSKRSSRSVEDDKE---GHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDH 176

Query: 211 KRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADD 250
            RG ++ VA+KI++N   Y    ++E+++L ++  +  ++
Sbjct: 177 ARGKSQ-VALKIIRNVGKYREAARLEINVLKKIKEKDKEN 215


>gi|10190706 CDC-like kinase 4 [Homo sapiens]
          Length = 481

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 1/55 (1%)

Query: 192 YEVLEFLGRGTFGQVVKCWKRGTNEI-VAIKILKNHPSYARQGQIEVSILARLST 245
           YE+++ LG G FG+VV+C   G + + VA+KI+KN   Y    + E+ +L  L++
Sbjct: 159 YEIVDTLGEGAFGKVVECIDHGMDGMHVAVKIVKNVGRYREAARSEIQVLEHLNS 213


>gi|241666392 CDC-like kinase 1 isoform 2 [Homo sapiens]
          Length = 526

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 1/55 (1%)

Query: 192 YEVLEFLGRGTFGQVVKCW-KRGTNEIVAIKILKNHPSYARQGQIEVSILARLST 245
           YE+++ LG G FG+VV+C   +     VA+KI+KN   Y    + E+ +L  L+T
Sbjct: 203 YEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNT 257


>gi|67551261 CDC-like kinase 1 isoform 1 [Homo sapiens]
          Length = 484

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 1/55 (1%)

Query: 192 YEVLEFLGRGTFGQVVKCW-KRGTNEIVAIKILKNHPSYARQGQIEVSILARLST 245
           YE+++ LG G FG+VV+C   +     VA+KI+KN   Y    + E+ +L  L+T
Sbjct: 161 YEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNT 215


>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
          Length = 346

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 23/48 (47%), Positives = 28/48 (58%), Gaps = 1/48 (2%)

Query: 187 SMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILK-NHPSYARQG 233
           S    YE L+FLG G F  V K   + TN+IVAIK +K  H S A+ G
Sbjct: 7   SRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDG 54


>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
          Length = 729

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 4/98 (4%)

Query: 148 QNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVV 207
           Q+  S  ++A+    ++  +N G   E   +  Q  +  ++T  Y+V   +G G F  V 
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQ--IPATITERYKVGRTIGDGNFAVVK 405

Query: 208 KCWKRGTNEIVAIKILKNHPSYARQGQI--EVSILARL 243
           +C +R T    A+KI+K      ++  I  EVSIL R+
Sbjct: 406 ECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV 443


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.124    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,361,394
Number of Sequences: 37866
Number of extensions: 403135
Number of successful extensions: 1858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 212
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 1547
Number of HSP's gapped (non-prelim): 374
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.