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Search of human proteins with 167860126
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 5 [Homo sapiens]
(375 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ... 749 0.0
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 314 9e-86
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 267 1e-71
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 266 3e-71
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 259 2e-69
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 259 3e-69
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 258 6e-69
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 258 6e-69
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 255 5e-68
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o... 245 4e-65
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 245 4e-65
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 240 2e-63
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 240 2e-63
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 240 2e-63
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (... 226 3e-59
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o... 226 3e-59
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 174 2e-43
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 165 7e-41
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 164 9e-41
gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (... 164 1e-40
gi|170295807 neuroserpin precursor [Homo sapiens] 159 3e-39
gi|4826904 neuroserpin precursor [Homo sapiens] 159 3e-39
gi|32454741 serine (or cysteine) proteinase inhibitor, clade H, ... 155 4e-38
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 153 2e-37
gi|73858566 heparin cofactor II precursor [Homo sapiens] 152 6e-37
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 151 8e-37
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 150 2e-36
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens] 147 2e-35
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 147 2e-35
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 147 2e-35
>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 5 [Homo sapiens]
Length = 375
Score = 749 bits (1934), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF
Sbjct: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
Query: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD
Sbjct: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
Query: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET
Sbjct: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
Query: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES
Sbjct: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
Query: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED
Sbjct: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
Query: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDELNADHPFIYIIRH 360
TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDELNADHPFIYIIRH
Sbjct: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDELNADHPFIYIIRH 360
Query: 361 NKTRNIIFFGKFCSP 375
NKTRNIIFFGKFCSP
Sbjct: 361 NKTRNIIFFGKFCSP 375
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 314 bits (804), Expect = 9e-86
Identities = 149/379 (39%), Positives = 237/379 (62%), Gaps = 4/379 (1%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
M+ L AN+ FA+DLF L E P GN+ SP +S+++++ +G +G+TA ++ + HF
Sbjct: 1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
Query: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
V++V FQ++ +D+NK + Y LKL RLY +K+ N EF+ ST++ Y +L +VD
Sbjct: 61 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
Query: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
F+ E+ + IN +K T+G +LA V++ TK+++VNA YF G W KF + T
Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
Query: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
PFR+NK D K V+MM + F G I+ + C+++ELP+Q + LSM ILLP D+EDES
Sbjct: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
Query: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
TGL+KIE+QL E L +WT P + +V +S+P+FK+E+ + L LG++ +F+
Sbjct: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
Query: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGA----RILQHKDELNADHPFIY 356
+D SGMS + + +S ++HK +E+ E+G ++ +L ++ ADHPF++
Sbjct: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
Query: 357 IIRHNKTRNIIFFGKFCSP 375
IRHN + +I+F G+F SP
Sbjct: 361 FIRHNSSGSILFLGRFSSP 379
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 267 bits (682), Expect = 1e-71
Identities = 131/380 (34%), Positives = 225/380 (59%), Gaps = 9/380 (2%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
M+ L A+ FA+ L K LC+ P NV SP+ +S++L++ +GAKG+TA ++ Q L
Sbjct: 1 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60
Query: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
+D+ FQ++ ++VNK + Y L+ RL+ +K+ + F S + Y EL+ +
Sbjct: 61 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS 120
Query: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
F EE++ IN + T+G E +L +S++ +T++++VNA YF GKW + F E+ T
Sbjct: 121 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT 180
Query: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
+E PF++N+ + +PVQMM EATF + ++ + +++ELP+ K LS+ +LLP D+
Sbjct: 181 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLP----DDG 236
Query: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
L +EK L E L+ WT P M + +V++ +PKFK+++ D ++ L +LG+ F +
Sbjct: 237 VELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQG 296
Query: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARI-----LQHKDELNADHPFI 355
+D S MS + + LS +HK +E+ E+G ++ + ++ ADHPF+
Sbjct: 297 KADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFL 356
Query: 356 YIIRHNKTRNIIFFGKFCSP 375
+ IRHN+ +I+F G+F SP
Sbjct: 357 FFIRHNRANSILFCGRFSSP 376
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 266 bits (679), Expect = 3e-71
Identities = 135/396 (34%), Positives = 238/396 (60%), Gaps = 27/396 (6%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
M++L AN+ F DLF+Q K N+ +SPI ++++L + +GAK +TA +I +VLHF
Sbjct: 1 MNSLSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59
Query: 61 ENVKDVPFG----------------FQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEF 104
+ V + G FQ + ++ NK + Y LK+ +L+ +K+ E+
Sbjct: 60 DQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEY 119
Query: 105 ISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNA 164
+ + K+ Y +E+VDF + EE++ +IN+ ++ T+ +N++ + ++ T +++VNA
Sbjct: 120 LDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNA 179
Query: 165 AYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNK 224
YF G+W KKF++ +TKE F NK K +QMM +F +++ + K++E+P++ K
Sbjct: 180 IYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGK 239
Query: 225 HLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDP 284
LSM +LLP +++ GL+K+E++L +E L +WT+ M +V L +P+FKVE+ D
Sbjct: 240 DLSMIVLLPNEID----GLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDL 295
Query: 285 KACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVP-----GA 339
K L +G+ IF+ D +D SGM+ ++G+ LS V+HK +E+TE+G ++ G+
Sbjct: 296 KDTLRTMGMVDIFNGD-ADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGS 354
Query: 340 RILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
+E + +HPF++ IR NKT +I+F+G+F SP
Sbjct: 355 SPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 259 bits (663), Expect = 2e-69
Identities = 143/382 (37%), Positives = 231/382 (60%), Gaps = 13/382 (3%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
MD L AN FA++L K L K+ NV FSP+ +S +L++ +GAKG+TA ++ Q+L F
Sbjct: 1 MDVLAEANGTFALNLLKTL-GKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
Query: 61 ENVK---DVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELE 117
D+ GFQ++ ++VNK + Y L++ RL+ +KS + + F S ++ Y E+E
Sbjct: 60 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
Query: 118 TVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSE 177
+DF +E+++ IN + + T+G +L+ SV+ T++++VNA YF G W ++F +
Sbjct: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
Query: 178 SETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVE 237
T+E F+V+K + KPVQMM ++TF I I +I+ LP+ K L+M I+LP
Sbjct: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLP---- 235
Query: 238 DESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIF 297
DE+T L +EK+L E +WT M +V++S+P+FK+E+ D ++ L NLG+ F
Sbjct: 236 DETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAF 295
Query: 298 SEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGA----RILQHKDELNADHP 353
+DFSGMS+T ++LS V+HK +E+ E+G ++ A R + ADHP
Sbjct: 296 ELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHP 354
Query: 354 FIYIIRHNKTRNIIFFGKFCSP 375
F++ I+H+KT I+F G+F SP
Sbjct: 355 FLFFIQHSKTNGILFCGRFSSP 376
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 259 bits (662), Expect = 3e-69
Identities = 142/401 (35%), Positives = 232/401 (57%), Gaps = 30/401 (7%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
MD+L + + FA++L K+L E N+ FS +STSL++ +GAKG TA ++ QVL F
Sbjct: 1 MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60
Query: 61 E----------------------NVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSL 98
N +++ FQT+ S++ K + Y LK +Y +K+
Sbjct: 61 NRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTY 120
Query: 99 NLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTK 158
+++ K + E + V+F + ++ + IN+ ++ T+G +N+L D+SV+ T+
Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180
Query: 159 ILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIE 218
+++VNA YF G W +F T E PFR+N+T +KPVQMM M+ + +I+ ++
Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240
Query: 219 LPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKV 278
L ++++ LS+ ILLP+D+ GLE++EK + E L++WT+ M +V+L +PKFK+
Sbjct: 241 LYYKSRDLSLLILLPEDI----NGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKL 296
Query: 279 EKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPG 338
E D K+ L ++G+ FS+ +DFSGMS + + LSNV HK +EI E G ++ G
Sbjct: 297 EDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSG 356
Query: 339 A----RILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
+ RI E NA+HPF++ IRHNKT I+F+G+ CSP
Sbjct: 357 SEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 258 bits (659), Expect = 6e-69
Identities = 143/379 (37%), Positives = 222/379 (58%), Gaps = 9/379 (2%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
MD L AN FA+ LFK L E++ NV FSP+ +S++L++ +GAKG TA ++ Q L
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
D+ GFQ++ S+VN+ + Y L+ RL+ +K+ + +F ++ Y ELE +
Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
F + EE + IN+ + + T+G +L +V+ TK+++VNA YF GKW ++F T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
+ F+ N+ + K VQMM EA F MG D ++ +++ELP+ + LSM ILLP D++
Sbjct: 181 RGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLP----DDN 235
Query: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
T L +EK L E WTN + +KV++ +P+ K+E+ D + L LG+ F E
Sbjct: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295
Query: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIE----VPGARILQHKDELNADHPFIY 356
+DFSGMS K V LS V HK +E+ E+G ++ V +R + + ADHPF++
Sbjct: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355
Query: 357 IIRHNKTRNIIFFGKFCSP 375
IRH+KT I+F G+F SP
Sbjct: 356 FIRHHKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 258 bits (659), Expect = 6e-69
Identities = 143/379 (37%), Positives = 222/379 (58%), Gaps = 9/379 (2%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
MD L AN FA+ LFK L E++ NV FSP+ +S++L++ +GAKG TA ++ Q L
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
D+ GFQ++ S+VN+ + Y L+ RL+ +K+ + +F ++ Y ELE +
Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
F + EE + IN+ + + T+G +L +V+ TK+++VNA YF GKW ++F T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
+ F+ N+ + K VQMM EA F MG D ++ +++ELP+ + LSM ILLP D++
Sbjct: 181 RGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLP----DDN 235
Query: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
T L +EK L E WTN + +KV++ +P+ K+E+ D + L LG+ F E
Sbjct: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295
Query: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIE----VPGARILQHKDELNADHPFIY 356
+DFSGMS K V LS V HK +E+ E+G ++ V +R + + ADHPF++
Sbjct: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355
Query: 357 IIRHNKTRNIIFFGKFCSP 375
IRH+KT I+F G+F SP
Sbjct: 356 FIRHHKTNCILFCGRFSSP 374
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 255 bits (651), Expect = 5e-68
Identities = 132/396 (33%), Positives = 233/396 (58%), Gaps = 27/396 (6%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
M++L AN+ F DLF+Q K N+ +SPI ++++L + +GAK +TA +I +VLHF
Sbjct: 1 MNSLSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59
Query: 61 ENVKD----------------VPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEF 104
+ V + V FQ + ++ NK + Y LK+ +L+ +K+ E+
Sbjct: 60 DQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEY 119
Query: 105 ISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNA 164
+ + K+ Y +E+ DF + EE++ +IN+ ++ T+ +N+ D ++ + T +++VNA
Sbjct: 120 LDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNA 179
Query: 165 AYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNK 224
YF G+W KF + TKE F NK K VQMM +F ++ + K++E+P++ K
Sbjct: 180 IYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGK 239
Query: 225 HLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDP 284
LSM +LLP +++ GL+K+E++L +E L +WT+ M V L +P+FK+E+ D
Sbjct: 240 DLSMIVLLPNEID----GLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDL 295
Query: 285 KACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQ- 343
K L +G+ +IF+ D +D SGM+ + G+++S V+HK +E+TE+G ++ +++
Sbjct: 296 KDTLRTMGMVNIFNGD-ADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVEL 354
Query: 344 ----HKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
+E +HPF++ IR NKT +I+F+G+F SP
Sbjct: 355 SSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 13 [Homo sapiens]
Length = 391
Score = 245 bits (626), Expect = 4e-65
Identities = 128/396 (32%), Positives = 227/396 (57%), Gaps = 26/396 (6%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLH- 59
MD+L ++ DLFK+L +K GN+ FSP+ + T++ + +G +G TA+++ +V H
Sbjct: 1 MDSLGAVSTRLGFDLFKEL-KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
Query: 60 ----------------FENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTE 103
EN + V FQ ++++KL++ Y L + RL+ +K+ +
Sbjct: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
Query: 104 FISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVN 163
++ ++ Y LE VDF + +E++ +IN+ ++ T+ +++ D S++ TK+++VN
Sbjct: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
Query: 164 AAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQN 223
YF G+W ++F + TKE F +NK+ +K VQMM +F ++ + KI+ +P++N
Sbjct: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
Query: 224 KHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMID 283
LSMF+LLP D++ GLEKI +++ E L +WT+P M KV L +P+F+VE D
Sbjct: 240 NDLSMFVLLPNDID----GLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYD 295
Query: 284 PKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPG----A 339
+A L +G+ FSE +D+SGMS G+ +H + +TE+G ++ G
Sbjct: 296 LEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTV 355
Query: 340 RILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
+ ++ +HPF++ IRHN++ +I+FFG+F SP
Sbjct: 356 TSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 12 [Homo sapiens]
Length = 405
Score = 245 bits (626), Expect = 4e-65
Identities = 125/405 (30%), Positives = 226/405 (55%), Gaps = 30/405 (7%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
MD+L AN+ F DLF+++ + + N+ FSP+ LS +L + ++GA+ D+A++I +VLHF
Sbjct: 1 MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60
Query: 61 ENVKD--------------------------VPFGFQTVTSDVNKLSSFYSLKLIKRLYV 94
V F + S ++++ + Y+L + RLY
Sbjct: 61 NEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 120
Query: 95 DKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVN 154
++ + E++ + Y +E+VDF+ E+++ +IN ++ + G + + + +++N
Sbjct: 121 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAIN 180
Query: 155 DQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINC 214
+T +++VNA YF KW F T + PF +N + K V+MM + + +G I+ +
Sbjct: 181 AETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 240
Query: 215 KIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIP 274
+I+E+ + LSMF+LLP +D GLE++E+++ E + W++ M+ V LS P
Sbjct: 241 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFP 300
Query: 275 KFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSI 334
+F +E D + L+++G+ IF E +D +G+S + + LS +IHK +E+ E+G +
Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360
Query: 335 EVPGA----RILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
GA R L+ E NA+HPF++ IRHNKT+ I+F+G+ CSP
Sbjct: 361 AATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 240 bits (612), Expect = 2e-63
Identities = 130/416 (31%), Positives = 230/416 (55%), Gaps = 42/416 (10%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
M+ L +AN+ FA++LFK L + P N+ SP +S+++++ +G++G T +++ +VL F
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 61 ENV-------------------------------------KDVPFGFQTVTSDVNKLSSF 83
V + F++++S +N +
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 84 YSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGH 143
Y L+ + +L+ +KS + E+I ++ Y+ E + VDF + EE + +IN+ +K T G
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 144 FENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEAT 203
N+L + SV+ T++++VNA YF GKW F + PFRVN PVQMM +
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 204 FCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPST 263
+G I+ + +I+ELP+ +SMF+LLP ++ D STGLE +E ++ + L++WT+
Sbjct: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
Query: 264 MANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVC 323
MA +V++ IP+FK+E+ + ++ L ++G++ F++ ++FSGMSE + LS V H+
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
Query: 324 LEITEDGGDSIEVPG----ARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
+++ E+G ++ G R + ADHPF+++I H T I+FFG+F SP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 240 bits (612), Expect = 2e-63
Identities = 130/416 (31%), Positives = 230/416 (55%), Gaps = 42/416 (10%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
M+ L +AN+ FA++LFK L + P N+ SP +S+++++ +G++G T +++ +VL F
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 61 ENV-------------------------------------KDVPFGFQTVTSDVNKLSSF 83
V + F++++S +N +
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 84 YSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGH 143
Y L+ + +L+ +KS + E+I ++ Y+ E + VDF + EE + +IN+ +K T G
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 144 FENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEAT 203
N+L + SV+ T++++VNA YF GKW F + PFRVN PVQMM +
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 204 FCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPST 263
+G I+ + +I+ELP+ +SMF+LLP ++ D STGLE +E ++ + L++WT+
Sbjct: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
Query: 264 MANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVC 323
MA +V++ IP+FK+E+ + ++ L ++G++ F++ ++FSGMSE + LS V H+
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
Query: 324 LEITEDGGDSIEVPG----ARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
+++ E+G ++ G R + ADHPF+++I H T I+FFG+F SP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 240 bits (612), Expect = 2e-63
Identities = 134/399 (33%), Positives = 224/399 (56%), Gaps = 31/399 (7%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
M +L AN F +D+FK+L N+ FS + L +LS+ +GA+G+T ++ +VLHF
Sbjct: 1 MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
Query: 61 ENVKD-----------------VPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTE 103
+ D + F S +N+ S +L + RLY K++ +
Sbjct: 61 SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
Query: 104 FISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVN 163
++S +++ Y L+TVDF+ EET+ IN +++ T+G N+ ++++ + +++VN
Sbjct: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
Query: 164 AAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQN 223
A YF G+W KF ET + PF++++ V+MM TF + + +++ELP+ N
Sbjct: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
Query: 224 KHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMID 283
LSM ILLP + L++IEKQLNS + +WT+ S M +V++ +P+FK+E +
Sbjct: 241 NKLSMIILLPVGI----ANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYE 296
Query: 284 PKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDG-------GDSIEV 336
+ L++LG+ +F++ +D SGMS TKG+ LS IHK L+++E+G GDSI V
Sbjct: 297 LNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAV 356
Query: 337 PGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
+ L + + A+HPF++ IRH T I+F GK SP
Sbjct: 357 ---KSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 226 bits (575), Expect = 3e-59
Identities = 128/389 (32%), Positives = 219/389 (56%), Gaps = 23/389 (5%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLH- 59
M +L AN+ F +LF+++ + + GNV FS + L +L+L ++GA+ D+ ++I ++LH
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 60 -----FENVKDVPFGFQT----VTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKR 110
+ N + G Q+ V SD+N Y L ++ L+ +K ++I ++
Sbjct: 61 NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120
Query: 111 PYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGK 170
Y ++E VDF + LE+T+ IN +++ T G +N++ + ++ +++VNA YF GK
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180
Query: 171 WMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFI 230
W F++SET C F+ K K V MM+ E F + I+ + KI+EL + N ++M++
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYV 239
Query: 231 LLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLEN 290
LLP++ L +IE +L ++L +WTNP M + V++ P+FK+EK + K L
Sbjct: 240 LLPEN------DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRA 293
Query: 291 LGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARI----LQHKD 346
LGLK IF E +D SG++ + +S ++HK +E+TE+G ++ G+ I L
Sbjct: 294 LGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQST 353
Query: 347 ELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
ADHPF+++IR K I+F GK P
Sbjct: 354 LFRADHPFLFVIR--KDDIILFSGKVSCP 380
>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 226 bits (575), Expect = 3e-59
Identities = 128/389 (32%), Positives = 219/389 (56%), Gaps = 23/389 (5%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLH- 59
M +L AN+ F +LF+++ + + GNV FS + L +L+L ++GA+ D+ ++I ++LH
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 60 -----FENVKDVPFGFQT----VTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKR 110
+ N + G Q+ V SD+N Y L ++ L+ +K ++I ++
Sbjct: 61 NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120
Query: 111 PYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGK 170
Y ++E VDF + LE+T+ IN +++ T G +N++ + ++ +++VNA YF GK
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180
Query: 171 WMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFI 230
W F++SET C F+ K K V MM+ E F + I+ + KI+EL + N ++M++
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYV 239
Query: 231 LLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLEN 290
LLP++ L +IE +L ++L +WTNP M + V++ P+FK+EK + K L
Sbjct: 240 LLPEN------DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRA 293
Query: 291 LGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARI----LQHKD 346
LGLK IF E +D SG++ + +S ++HK +E+TE+G ++ G+ I L
Sbjct: 294 LGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQST 353
Query: 347 ELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
ADHPF+++IR K I+F GK P
Sbjct: 354 LFRADHPFLFVIR--KDDIILFSGKVSCP 380
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 174 bits (440), Expect = 2e-43
Identities = 104/376 (27%), Positives = 199/376 (52%), Gaps = 17/376 (4%)
Query: 8 NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVK--D 65
N+ FAVDL++++ N++FSP+ ++ L + Q+GAKG +I Q L + +
Sbjct: 26 NTEFAVDLYQEVSLSHK-DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGE 84
Query: 66 VPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKL 125
F ++ S +++ ++ L LY+ + + +++ K + ++ VDF+D
Sbjct: 85 EFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDA- 143
Query: 126 EETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPF 185
+ I+ ++ TDG +++ + T++++VNA YF G W +KF + +T+ F
Sbjct: 144 KACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINF 203
Query: 186 RVNKTDTKPVQMMN--MEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGL 243
T + MM + + + S+N +++EL ++ S+ I+LP E +
Sbjct: 204 TKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPA----EGMDI 259
Query: 244 EKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSD 303
E++EK + ++ + +W S M +V++S+P+FKVE+ +D K L +L + IFS D
Sbjct: 260 EEVEKLITAQQILKWL--SEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFS-GGCD 316
Query: 304 FSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARI----LQHKDELNADHPFIYIIR 359
SG++++ V +S V KV EI EDG ++ G I + + A+HPF++I++
Sbjct: 317 LSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMK 376
Query: 360 HNKTRNIIFFGKFCSP 375
HN T +I+F G+ +P
Sbjct: 377 HNPTESILFMGRVTNP 392
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 165 bits (417), Expect = 7e-41
Identities = 110/381 (28%), Positives = 198/381 (51%), Gaps = 27/381 (7%)
Query: 8 NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVP 67
N+ FA +L+++ + P N+ FSP+ +S +L + GA T EI + L F N+ D P
Sbjct: 46 NADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGF-NLTDTP 104
Query: 68 F-----GFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFK 122
GFQ + +N L++ L++ K L +F++ K Y E+ + DF
Sbjct: 105 MVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFS 164
Query: 123 DKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKE 182
+ + K +IN+ ++ T G ++ D N T +++VN +F +W F S+T++
Sbjct: 165 N-ISAAKQEINSHVEMQTKGKVVGLIQDLKPN--TIMVLVNYIHFKAQWANPFDPSKTED 221
Query: 183 CP-FRVNKTDTKPVQMMN-MEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
F ++KT T V MM+ ME + + +++ +NC ++++ + L++F+L PK+ +
Sbjct: 222 SSSFLIDKTTTVQVPMMHQMEQYYHLVDME-LNCTVLQMDYSKNALALFVL-PKEGQ--- 276
Query: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
+E +E ++S++L +W + V L +PKF + D A L +G++H +SE+
Sbjct: 277 --MESVEAAMSSKTLKKWNR--LLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSEN 332
Query: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDE------LNADHPF 354
+DFSG++E G+ LSN HK L I E G ++ VP + + + D F
Sbjct: 333 -ADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSF 391
Query: 355 IYIIRHNKTRNIIFFGKFCSP 375
+ +I TR+I+F GK +P
Sbjct: 392 MLLILERSTRSILFLGKVVNP 412
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 164 bits (416), Expect = 9e-41
Identities = 101/386 (26%), Positives = 193/386 (50%), Gaps = 21/386 (5%)
Query: 4 LQLANSAFAVDLFKQLCE-KEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFEN 62
L ANS FA ++ L + K N+ SP+ +ST+ ++ ++GA DT ++ +V F+
Sbjct: 83 LSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDT 142
Query: 63 VKD-----VPFGFQTVTSDV-NKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKEL 116
+ + + F F + + K + L RL+ DKSL + + ++ Y +L
Sbjct: 143 ISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKL 202
Query: 117 ETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFS 176
+ +DFK+ E+++ IN + + T+G +++ ++N+ T +++VN YF G W KFS
Sbjct: 203 QPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFS 262
Query: 177 ESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDV 236
T++ F ++ MM E F + + +++ELPF+ ++M ++LPK
Sbjct: 263 PENTRKELFYKADGESCSASMMYQEGKFRYRRV-AEGTQVLELPFKGDDITMVLILPK-- 319
Query: 237 EDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHI 296
L K+EK+L E L +W + + + + +P+F++E K L+++GL +
Sbjct: 320 --PEKSLAKVEKELTPEVLQEWLD--ELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDL 375
Query: 297 FSEDTSDFSGM--SETKGVALSNVIHKVCLEITEDGGD-----SIEVPGARILQHKDELN 349
FS + S G+ + +S+ HK LE+ E+G + ++ + G + ++
Sbjct: 376 FSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFK 435
Query: 350 ADHPFIYIIRHNKTRNIIFFGKFCSP 375
A+ PF+ IR IIF G+ +P
Sbjct: 436 ANRPFLVFIREVPLNTIIFMGRVANP 461
>gi|73623033 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform b [Homo sapiens]
Length = 242
Score = 164 bits (415), Expect = 1e-40
Identities = 90/238 (37%), Positives = 142/238 (59%), Gaps = 1/238 (0%)
Query: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
MD L AN FA+ LFK L E++ NV FSP+ +S++L++ +GAKG TA ++ Q L
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
D+ GFQ++ S+VN+ + Y L+ RL+ +K+ + +F ++ Y ELE +
Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
F + EE + IN+ + + T+G +L +V+ TK+++VNA YF GKW ++F T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVED 238
+ F+ N+ + K VQMM EA F MG D ++ +++ELP+ + LSM ILLP D D
Sbjct: 181 RGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTD 237
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 159 bits (403), Expect = 3e-39
Identities = 98/376 (26%), Positives = 196/376 (52%), Gaps = 20/376 (5%)
Query: 12 AVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKD-VPFGF 70
+V+++ +L N+LFSP+ ++ ++ + ++GA+G T EI + ++++K+ F F
Sbjct: 30 SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSF 89
Query: 71 QTVTSD-VNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETK 129
S+ V S Y +K+ L+V +++ EF+ K+ + + VDF +
Sbjct: 90 LKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVA-VA 148
Query: 130 GQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNK 189
IN +++ T+ +++++ + T + ++NA YF G W +F T+ F +
Sbjct: 149 NYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDD 208
Query: 190 TDTKPVQMMNMEATFCMGNI-DSIN-----CKIIELPFQNKHLSMFILLPKDVEDESTGL 243
+ MM + F G D N +++E+P++ +SM ++L + + L
Sbjct: 209 ESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSR----QEVPL 264
Query: 244 EKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSD 303
+E + ++ + +W N ++ KV++ +P+F VE+ ID K L+ LG+ IF +D ++
Sbjct: 265 ATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-AN 321
Query: 304 FSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPG----ARILQHKDELNADHPFIYIIR 359
+G+S+ K + LS IHK LE+ E+G ++ V G +R+ ++ DHPF ++IR
Sbjct: 322 LTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381
Query: 360 HNKTRNIIFFGKFCSP 375
+ +T I+F G+ P
Sbjct: 382 NRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 159 bits (403), Expect = 3e-39
Identities = 98/376 (26%), Positives = 196/376 (52%), Gaps = 20/376 (5%)
Query: 12 AVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKD-VPFGF 70
+V+++ +L N+LFSP+ ++ ++ + ++GA+G T EI + ++++K+ F F
Sbjct: 30 SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSF 89
Query: 71 QTVTSD-VNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETK 129
S+ V S Y +K+ L+V +++ EF+ K+ + + VDF +
Sbjct: 90 LKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVA-VA 148
Query: 130 GQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNK 189
IN +++ T+ +++++ + T + ++NA YF G W +F T+ F +
Sbjct: 149 NYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDD 208
Query: 190 TDTKPVQMMNMEATFCMGNI-DSIN-----CKIIELPFQNKHLSMFILLPKDVEDESTGL 243
+ MM + F G D N +++E+P++ +SM ++L + + L
Sbjct: 209 ESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSR----QEVPL 264
Query: 244 EKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSD 303
+E + ++ + +W N ++ KV++ +P+F VE+ ID K L+ LG+ IF +D ++
Sbjct: 265 ATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-AN 321
Query: 304 FSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPG----ARILQHKDELNADHPFIYIIR 359
+G+S+ K + LS IHK LE+ E+G ++ V G +R+ ++ DHPF ++IR
Sbjct: 322 LTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381
Query: 360 HNKTRNIIFFGKFCSP 375
+ +T I+F G+ P
Sbjct: 382 NRRTGTILFMGRVMHP 397
>gi|32454741 serine (or cysteine) proteinase inhibitor, clade H,
member 1 precursor [Homo sapiens]
Length = 418
Score = 155 bits (393), Expect = 4e-38
Identities = 109/372 (29%), Positives = 182/372 (48%), Gaps = 13/372 (3%)
Query: 8 NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKD-- 65
++ A L++ + + + + N+L SP+ +++SL L +G K TA++ VL E ++D
Sbjct: 47 SAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEE 106
Query: 66 VPFGF-QTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDK 124
V G + + S N + + KL RLY S++ + +F+ S+K+ Y E ++F+DK
Sbjct: 107 VHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDK 166
Query: 125 LEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECP 184
+ IN TDG + D D L+VNA +F W +KF
Sbjct: 167 RSALQS-INEWAAQTTDGKLPEVTKDVERTDGA--LLVNAMFFKPHWDEKFHHKMVDNRG 223
Query: 185 FRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLE 244
F V ++ T V MM+ + + + +I+E+P +K S+ IL+P VE LE
Sbjct: 224 FMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEP----LE 279
Query: 245 KIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDF 304
++EK L E L W M V +S+PK VE D + L LGL ++ +D
Sbjct: 280 RLEKLLTKEQLKIWM--GKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADL 337
Query: 305 SGMSETKGVALSNVIHKVCLEITEDGGD-SIEVPGARILQHKDELNADHPFIYIIRHNKT 363
S MS K + L++V H E+ DG ++ G L+ ADHPFI+++R ++
Sbjct: 338 SRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQS 397
Query: 364 RNIIFFGKFCSP 375
+++F G+ P
Sbjct: 398 GSLLFIGRLVRP 409
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 153 bits (387), Expect = 2e-37
Identities = 108/383 (28%), Positives = 190/383 (49%), Gaps = 22/383 (5%)
Query: 4 LQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFE-- 61
L AN FA L+KQL K P NV+FSP+ +ST+L+ +GA T EI + L F
Sbjct: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
Query: 62 --NVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETV 119
+ ++ FQ + +N+ S L + ++V + L+L F KR Y E
Sbjct: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168
Query: 120 DFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESE 179
DF+D K IN+ +K+ T G +++ D ++ QT +++VN +F KW F +
Sbjct: 169 DFQDS-AAAKKLINDYVKNGTRGKITDLIKD--LDSQTMMVLVNYIFFKAKWEMPFDPQD 225
Query: 180 TKECPFRVNKTDTKPVQMMNM-EATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVED 238
T + F ++K V MM++ T + ++C ++EL + ++FIL +D
Sbjct: 226 THQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQD--- 282
Query: 239 ESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFS 298
+E++E L E+L +W + S +L +PKF + + + L LG++ F+
Sbjct: 283 ---KMEEVEAMLLPETLKRWRD-SLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFT 338
Query: 299 EDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARI------LQHKDELNADH 352
+D SG++ + +A+S V+HK L++ E+G ++ +I ++ + + +
Sbjct: 339 -SKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNR 397
Query: 353 PFIYIIRHNKTRNIIFFGKFCSP 375
PF+ II T+NI F K +P
Sbjct: 398 PFLMIIVPTDTQNIFFMSKVTNP 420
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 152 bits (383), Expect = 6e-37
Identities = 94/384 (24%), Positives = 198/384 (51%), Gaps = 25/384 (6%)
Query: 4 LQLANSAFAVDLFKQLCEK-EPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFEN 62
L + N+ FA +L++ L ++ N+ +P+ +ST++ + +G KG+T ++ +LHF++
Sbjct: 126 LNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKD 185
Query: 63 ---------VKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYA 113
+ + F+ +T + + + Y+L+ + LY+ K + +F + + Y
Sbjct: 186 FVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYF 245
Query: 114 KELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMK 173
E + DF D +K NN I LT G ++ L +++ T+++++N YF G W+
Sbjct: 246 AEAQIADFSDPAFISK--TNNHIMKLTKGLIKDAL--ENIDPATQMMILNCIYFKGSWVN 301
Query: 174 KFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLP 233
KF T FR+N+ + V MM + F N ++C I++L + +SM I++P
Sbjct: 302 KFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GISMLIVVP 360
Query: 234 KDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGL 293
+ +G++ +E QL + +W +M N ++ +PKFK+EK + L+ +G+
Sbjct: 361 ----HKMSGMKTLEAQLTPRVVERW--QKSMTNRTREVLLPKFKLEKNYNLVESLKLMGI 414
Query: 294 KHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDG--GDSIEVPGARILQHKDELNAD 351
+ +F ++ + +G+S+ + +A+ H+ + + E+G ++ G L + D
Sbjct: 415 RMLFDKN-GNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVD 472
Query: 352 HPFIYIIRHNKTRNIIFFGKFCSP 375
PF+++I ++T ++F G+ +P
Sbjct: 473 RPFLFLIYEHRTSCLLFMGRVANP 496
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 151 bits (382), Expect = 8e-37
Identities = 102/380 (26%), Positives = 199/380 (52%), Gaps = 25/380 (6%)
Query: 8 NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVP 67
N+ FA L+++L + P N+ FSP+ +STSL++ +GA T +I Q L F N+ P
Sbjct: 66 NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGF-NLTHTP 124
Query: 68 -----FGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFK 122
GFQ + + S +LK+ L+V K L L F+ + KR Y E+ + DF
Sbjct: 125 ESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFS 184
Query: 123 DKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET-K 181
+ + +IN+ +K T G +I+ ++ T +++VN +F KW K F T K
Sbjct: 185 NP-SIAQARINSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRK 241
Query: 182 ECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDEST 241
PF V + T V MM+ + F G +NC ++++ ++ ++ F+L K
Sbjct: 242 NFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKG------ 295
Query: 242 GLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDT 301
+ ++E+ L++ +L +W++ ++ +++ IP+F + + + L +G++++F ++
Sbjct: 296 KMRQLEQALSARTLRKWSH--SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN- 352
Query: 302 SDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGAR-ILQHKD-----ELNADHPFI 355
+DFSG+++ + +S HK L+++E+G ++ + I++ KD ++ + F+
Sbjct: 353 ADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFL 412
Query: 356 YIIRHNKTRNIIFFGKFCSP 375
+I + T I+F GK +P
Sbjct: 413 MMITNKATDGILFLGKVENP 432
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 150 bits (379), Expect = 2e-36
Identities = 104/381 (27%), Positives = 190/381 (49%), Gaps = 18/381 (4%)
Query: 1 MDALQLA--NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVL 58
M A +LA N L K+L P N+ SP+ +ST+ S+ +GA+ T +EI Q
Sbjct: 43 MAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGF 102
Query: 59 HFENV--KDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKEL 116
+F + KD+ GF + ++ + + L + L++D+ L +F+ K Y+ E
Sbjct: 103 NFRKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAET 162
Query: 117 ETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFS 176
+F++ LE + QIN+ I T G N++ +++ T +L+ N +F +W +F
Sbjct: 163 ILTNFQN-LEMAQKQINDFISQKTHGKINNLI--ENIDPGTVMLLANYIFFRARWKHEFD 219
Query: 177 ESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDV 236
+ TKE F + K + V MM + +G D ++C I+E+P+Q ++FIL
Sbjct: 220 PNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFIL----- 274
Query: 237 EDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHI 296
DE L+ +EK L ++ S+W + ++ V +S+P+ + D K L +G+ I
Sbjct: 275 PDEGK-LKHLEKGLQVDTFSRW--KTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKI 331
Query: 297 FSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDEL--NADHPF 354
F E+ D + ++ + + + +HK L++ E G + GA+ L + L D P+
Sbjct: 332 F-EEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPY 390
Query: 355 IYIIRHNKTRNIIFFGKFCSP 375
+ +I K +++F GK +P
Sbjct: 391 LLLIYSEKIPSVLFLGKIVNP 411
>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
Length = 402
Score = 147 bits (371), Expect = 2e-35
Identities = 102/375 (27%), Positives = 185/375 (49%), Gaps = 16/375 (4%)
Query: 9 SAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFE-NVKDVP 67
S F V +F+Q+ + NV+FSP +++ L++ Q+ G+T +I + F+ + K +
Sbjct: 36 SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMA 95
Query: 68 FGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEE 127
+ + ++ + + ++V + L L F+ R + ++ VDF + +E
Sbjct: 96 PALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSE-VER 154
Query: 128 TKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRV 187
+ IN+ +K T G N+L +V+ T++++VNA YF G+W F +S T F
Sbjct: 155 ARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHK 214
Query: 188 NKTDTKPVQMMNMEATFCMGNI---DSINCKIIELPFQNKHLSMFILLPKDVEDESTGLE 244
+ T V MM F D I+ELP+ LSMFI P + E + L
Sbjct: 215 SDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALT 274
Query: 245 KIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDF 304
I L+++ +S W M L +PKF +E +D + LENLG+ +F + +DF
Sbjct: 275 NI---LSAQLISHW--KGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADF 329
Query: 305 SGMSETKGVALSNVIHKVCLEITEDG----GDSIEVPGARILQHKDELNADHPFIYIIRH 360
+ +S+ + + ++ + KV +E+ E G + + AR+ +E+ D PF++++RH
Sbjct: 330 TSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMA--PEEIIMDRPFLFVVRH 387
Query: 361 NKTRNIIFFGKFCSP 375
N T ++F G+ P
Sbjct: 388 NPTGTVLFMGQVMEP 402
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 147 bits (370), Expect = 2e-35
Identities = 104/375 (27%), Positives = 188/375 (50%), Gaps = 26/375 (6%)
Query: 11 FAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVP--- 67
FA L++QL + N+ FSP+ ++T+ ++ +G K DT +EI + L+F N+ ++P
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNF-NLTEIPEAQ 115
Query: 68 --FGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKL 125
GFQ + +N+ S L L++ + L L +F+ K+ Y E TV+F D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-T 174
Query: 126 EETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPF 185
EE K QIN+ ++ T G +++ + ++ T +VN +F GKW + F +T+E F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232
Query: 186 RVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEK 245
V++ T V MM F + + ++ ++ + + ++F L DE L+
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL-----PDEGK-LQH 286
Query: 246 IEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFS 305
+E +L + ++++ +A L +PK + D K+ L LG+ +FS + +D S
Sbjct: 287 LENELTHDIITKFLENEDRRSA--SLHLPKLSITGTYDLKSVLGQLGITKVFS-NGADLS 343
Query: 306 GMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQH-----KDELNADHPFIYIIRH 360
G++E + LS +HK L I E G E GA L+ E+ + PF++++
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKG---TEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIE 400
Query: 361 NKTRNIIFFGKFCSP 375
T++ +F GK +P
Sbjct: 401 QNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 147 bits (370), Expect = 2e-35
Identities = 104/375 (27%), Positives = 188/375 (50%), Gaps = 26/375 (6%)
Query: 11 FAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVP--- 67
FA L++QL + N+ FSP+ ++T+ ++ +G K DT +EI + L+F N+ ++P
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNF-NLTEIPEAQ 115
Query: 68 --FGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKL 125
GFQ + +N+ S L L++ + L L +F+ K+ Y E TV+F D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-T 174
Query: 126 EETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPF 185
EE K QIN+ ++ T G +++ + ++ T +VN +F GKW + F +T+E F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232
Query: 186 RVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEK 245
V++ T V MM F + + ++ ++ + + ++F L DE L+
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL-----PDEGK-LQH 286
Query: 246 IEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFS 305
+E +L + ++++ +A L +PK + D K+ L LG+ +FS + +D S
Sbjct: 287 LENELTHDIITKFLENEDRRSA--SLHLPKLSITGTYDLKSVLGQLGITKVFS-NGADLS 343
Query: 306 GMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQH-----KDELNADHPFIYIIRH 360
G++E + LS +HK L I E G E GA L+ E+ + PF++++
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKG---TEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIE 400
Query: 361 NKTRNIIFFGKFCSP 375
T++ +F GK +P
Sbjct: 401 QNTKSPLFMGKVVNP 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,799,270
Number of Sequences: 37866
Number of extensions: 517118
Number of successful extensions: 1704
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1444
Number of HSP's gapped (non-prelim): 84
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.