Guide to the Human Genome
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Search of human proteins with 16604248

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16604248 septin 1 [Homo sapiens]
         (367 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16604248 septin 1 [Homo sapiens]                                   736   0.0  
gi|4758942 septin 4 isoform 1 [Homo sapiens]                          484   e-137
gi|17986247 septin 4 isoform 3 [Homo sapiens]                         484   e-137
gi|9945439 septin 5 [Homo sapiens]                                    478   e-135
gi|56549640 septin 2 [Homo sapiens]                                   400   e-111
gi|56549638 septin 2 [Homo sapiens]                                   400   e-111
gi|56549636 septin 2 [Homo sapiens]                                   400   e-111
gi|4758158 septin 2 [Homo sapiens]                                    400   e-111
gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]          349   3e-96
gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]          349   3e-96
gi|156602655 septin 3 isoform A [Homo sapiens]                        278   6e-75
gi|156602653 septin 3 isoform B [Homo sapiens]                        278   6e-75
gi|164698504 septin 9 isoform f [Homo sapiens]                        271   5e-73
gi|164698502 septin 9 isoform d [Homo sapiens]                        271   5e-73
gi|164698500 septin 9 isoform e [Homo sapiens]                        271   5e-73
gi|164698498 septin 9 isoform b [Homo sapiens]                        271   5e-73
gi|164698496 septin 9 isoform e [Homo sapiens]                        271   5e-73
gi|164698494 septin 9 isoform a [Homo sapiens]                        271   5e-73
gi|116256489 septin 9 isoform c [Homo sapiens]                        271   5e-73
gi|226492421 septin 12 isoform 2 [Homo sapiens]                       253   2e-67
gi|8922712 septin 11 [Homo sapiens]                                   246   2e-65
gi|30795193 septin 10 isoform 2 [Homo sapiens]                        243   2e-64
gi|21945064 septin 10 isoform 1 [Homo sapiens]                        243   2e-64
gi|21361478 septin 6 isoform B [Homo sapiens]                         243   3e-64
gi|22035581 septin 6 isoform D [Homo sapiens]                         243   3e-64
gi|22035579 septin 6 isoform A [Homo sapiens]                         243   3e-64
gi|22035577 septin 6 isoform A [Homo sapiens]                         243   3e-64
gi|149363638 septin 8 isoform c [Homo sapiens]                        242   4e-64
gi|149363689 septin 8 isoform a [Homo sapiens]                        242   4e-64
gi|149363661 septin 8 isoform b [Homo sapiens]                        242   4e-64

>gi|16604248 septin 1 [Homo sapiens]
          Length = 367

 Score =  736 bits (1899), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS
Sbjct: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
           ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD
Sbjct: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120

Query: 121 ESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQET 180
           ESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQET
Sbjct: 121 ESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQET 180

Query: 181 QALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNR 240
           QALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNR
Sbjct: 181 QALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNR 240

Query: 241 PVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARP 300
           PVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARP
Sbjct: 241 PVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARP 300

Query: 301 GARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQ 360
           GARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQ
Sbjct: 301 GARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQ 360

Query: 361 GEQSDAL 367
           GEQSDAL
Sbjct: 361 GEQSDAL 367


>gi|4758942 septin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score =  484 bits (1246), Expect = e-137
 Identities = 234/359 (65%), Positives = 294/359 (81%), Gaps = 5/359 (1%)

Query: 2   DKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASA 61
           DKEYVGFA LPNQ+HRKSVKKGFDFTLMVAGESGLGKSTL+NSLFLT+LY DR++  A  
Sbjct: 121 DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEE 180

Query: 62  RLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDE 121
           R+ QT+ I +  V+IEE GV+++LT+VDTPGFGD+V+ ++CW PV ++I++QFEQY RDE
Sbjct: 181 RIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDE 240

Query: 122 SGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQ 181
           SGLNRKNIQD+RVHCCLYFISPFG GLRPLDV F++A+H++VNI+P++ KAD L P E  
Sbjct: 241 SGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD 300

Query: 182 ALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRP 241
             K+KIR++++   I IYQFP+CDSDEDEDFK QD  +KESIPFAV+GS  VV   G R 
Sbjct: 301 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRR- 359

Query: 242 VRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPG 301
           VRGR Y WG VEVENP HCDF+ LR MLV+TH+QDLK+VT +  YE YRA+C+QS+ R  
Sbjct: 360 VRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLV 419

Query: 302 ARDRASRSKLSRQSATEIPLPMLPLA---DTEKLIREKDEELRRMQEMLEKMQAQMQQS 357
            ++R +R+KL+R+S T+ P+P +P     +TEKLIREKDEELRRMQEML K+Q QM+++
Sbjct: 420 VKER-NRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKEN 477


>gi|17986247 septin 4 isoform 3 [Homo sapiens]
          Length = 459

 Score =  484 bits (1246), Expect = e-137
 Identities = 234/359 (65%), Positives = 294/359 (81%), Gaps = 5/359 (1%)

Query: 2   DKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASA 61
           DKEYVGFA LPNQ+HRKSVKKGFDFTLMVAGESGLGKSTL+NSLFLT+LY DR++  A  
Sbjct: 102 DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEE 161

Query: 62  RLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDE 121
           R+ QT+ I +  V+IEE GV+++LT+VDTPGFGD+V+ ++CW PV ++I++QFEQY RDE
Sbjct: 162 RIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDE 221

Query: 122 SGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQ 181
           SGLNRKNIQD+RVHCCLYFISPFG GLRPLDV F++A+H++VNI+P++ KAD L P E  
Sbjct: 222 SGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD 281

Query: 182 ALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRP 241
             K+KIR++++   I IYQFP+CDSDEDEDFK QD  +KESIPFAV+GS  VV   G R 
Sbjct: 282 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRR- 340

Query: 242 VRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPG 301
           VRGR Y WG VEVENP HCDF+ LR MLV+TH+QDLK+VT +  YE YRA+C+QS+ R  
Sbjct: 341 VRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLV 400

Query: 302 ARDRASRSKLSRQSATEIPLPMLPLA---DTEKLIREKDEELRRMQEMLEKMQAQMQQS 357
            ++R +R+KL+R+S T+ P+P +P     +TEKLIREKDEELRRMQEML K+Q QM+++
Sbjct: 401 VKER-NRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKEN 458


>gi|9945439 septin 5 [Homo sapiens]
          Length = 369

 Score =  478 bits (1229), Expect = e-135
 Identities = 231/359 (64%), Positives = 291/359 (81%), Gaps = 15/359 (4%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +DK+YVGFA LPNQ+HRKSVKKGFDFTLMVAGESGLGKSTL++SLFLT+LY+DR++  A 
Sbjct: 20  IDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAE 79

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R++QT+ I +  V+IEE GVK+KLT+VDTPGFGD+V+ ++CW P+  ++++QFEQY RD
Sbjct: 80  ERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRD 139

Query: 121 ESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQET 180
           ESGLNRKNIQD+RVHCCLYFISPFG GLRP+DV F++A+HEKVNI+P+I KAD L+P E 
Sbjct: 140 ESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEI 199

Query: 181 QALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNR 240
           + LK++IR+++ +  IH+YQFPECDSDEDEDFK+QD E+KES PFAV+GS  VV   G R
Sbjct: 200 RKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQR 259

Query: 241 PVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARP 300
            VRGR Y WG VEVEN  HCDF+ LR ML++TH+ DLK+VT D+ YE YRA C+Q +   
Sbjct: 260 -VRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT-- 316

Query: 301 GARDRASRSKLSRQSATEIPLPMLPL----ADTEKLIREKDEELRRMQEMLEKMQAQMQ 355
                   SKL++ S  E P+P+LPL    A+TEKLIR KDEELRRMQEML++M+ QMQ
Sbjct: 317 --------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQ 367


>gi|56549640 septin 2 [Homo sapiens]
          Length = 361

 Score =  400 bits (1028), Expect = e-111
 Identities = 202/361 (55%), Positives = 264/361 (73%), Gaps = 24/361 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           YVGFA LPNQ+HRKSVKKGF+FTLMV GESGLGKSTLINSLFLT+LY +R +P A+ ++ 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ IE   VEIEE GVK++LT+VDTPG+GD+++C DC+  ++ +I+EQFE+YL DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 125 NRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
           NR++I D+RVHCC YFISPFG GL+PLDVAF++A+H KVNI+PVI KAD L  +E + LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
           ++I D+++E  I IY  P+ +SDEDEDFK Q   +K SIPF+VVGS +++   G + VRG
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKK-VRG 255

Query: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARD 304
           R Y WG VEVENP H DFL LR ML+ TH+QDL+EVT DL YE +R+  L+   R    +
Sbjct: 256 RLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE 314

Query: 305 RASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQS 364
             ++                     ++++ EK+ ELRRMQEM+ +MQAQMQ  Q QG   
Sbjct: 315 DMNK---------------------DQILLEKEAELRRMQEMIARMQAQMQM-QMQGGDG 352

Query: 365 D 365
           D
Sbjct: 353 D 353


>gi|56549638 septin 2 [Homo sapiens]
          Length = 361

 Score =  400 bits (1028), Expect = e-111
 Identities = 202/361 (55%), Positives = 264/361 (73%), Gaps = 24/361 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           YVGFA LPNQ+HRKSVKKGF+FTLMV GESGLGKSTLINSLFLT+LY +R +P A+ ++ 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ IE   VEIEE GVK++LT+VDTPG+GD+++C DC+  ++ +I+EQFE+YL DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 125 NRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
           NR++I D+RVHCC YFISPFG GL+PLDVAF++A+H KVNI+PVI KAD L  +E + LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
           ++I D+++E  I IY  P+ +SDEDEDFK Q   +K SIPF+VVGS +++   G + VRG
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKK-VRG 255

Query: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARD 304
           R Y WG VEVENP H DFL LR ML+ TH+QDL+EVT DL YE +R+  L+   R    +
Sbjct: 256 RLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE 314

Query: 305 RASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQS 364
             ++                     ++++ EK+ ELRRMQEM+ +MQAQMQ  Q QG   
Sbjct: 315 DMNK---------------------DQILLEKEAELRRMQEMIARMQAQMQM-QMQGGDG 352

Query: 365 D 365
           D
Sbjct: 353 D 353


>gi|56549636 septin 2 [Homo sapiens]
          Length = 361

 Score =  400 bits (1028), Expect = e-111
 Identities = 202/361 (55%), Positives = 264/361 (73%), Gaps = 24/361 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           YVGFA LPNQ+HRKSVKKGF+FTLMV GESGLGKSTLINSLFLT+LY +R +P A+ ++ 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ IE   VEIEE GVK++LT+VDTPG+GD+++C DC+  ++ +I+EQFE+YL DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 125 NRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
           NR++I D+RVHCC YFISPFG GL+PLDVAF++A+H KVNI+PVI KAD L  +E + LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
           ++I D+++E  I IY  P+ +SDEDEDFK Q   +K SIPF+VVGS +++   G + VRG
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKK-VRG 255

Query: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARD 304
           R Y WG VEVENP H DFL LR ML+ TH+QDL+EVT DL YE +R+  L+   R    +
Sbjct: 256 RLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE 314

Query: 305 RASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQS 364
             ++                     ++++ EK+ ELRRMQEM+ +MQAQMQ  Q QG   
Sbjct: 315 DMNK---------------------DQILLEKEAELRRMQEMIARMQAQMQM-QMQGGDG 352

Query: 365 D 365
           D
Sbjct: 353 D 353


>gi|4758158 septin 2 [Homo sapiens]
          Length = 361

 Score =  400 bits (1028), Expect = e-111
 Identities = 202/361 (55%), Positives = 264/361 (73%), Gaps = 24/361 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           YVGFA LPNQ+HRKSVKKGF+FTLMV GESGLGKSTLINSLFLT+LY +R +P A+ ++ 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ IE   VEIEE GVK++LT+VDTPG+GD+++C DC+  ++ +I+EQFE+YL DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 125 NRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
           NR++I D+RVHCC YFISPFG GL+PLDVAF++A+H KVNI+PVI KAD L  +E + LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
           ++I D+++E  I IY  P+ +SDEDEDFK Q   +K SIPF+VVGS +++   G + VRG
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKK-VRG 255

Query: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARD 304
           R Y WG VEVENP H DFL LR ML+ TH+QDL+EVT DL YE +R+  L+   R    +
Sbjct: 256 RLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE 314

Query: 305 RASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQS 364
             ++                     ++++ EK+ ELRRMQEM+ +MQAQMQ  Q QG   
Sbjct: 315 DMNK---------------------DQILLEKEAELRRMQEMIARMQAQMQM-QMQGGDG 352

Query: 365 D 365
           D
Sbjct: 353 D 353


>gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]
          Length = 437

 Score =  349 bits (895), Expect = 3e-96
 Identities = 176/363 (48%), Positives = 257/363 (70%), Gaps = 16/363 (4%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           YVGFA LPNQ++RKSVK+GF+FTLMV GESGLGKSTLINSLFLT+LY   + P  S R+ 
Sbjct: 30  YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 88

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ +E+  V I+EGGV++ LT+VDTPGFGD+VD S+CW PV+ +I+ +FE YL  ES +
Sbjct: 89  KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 148

Query: 125 NRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
           NR+ + D+RV CCLYFI+P G GL+PLD+ F++ +HEKVNIIP+I KAD L P+E Q  K
Sbjct: 149 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 208

Query: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
           ++I  +++E +I IY+FPE D +E+    +   ++K+ +P AVVGS  ++   G R VRG
Sbjct: 209 KQIMKEIQEHKIKIYEFPETDDEEENKLVK---KIKDRLPLAVVGSNTIIEVNGKR-VRG 264

Query: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARD 304
           R+Y WG  EVEN  HCDF  LR ML++TH+QDLK+VT+++ YE YR+R L ++   G  +
Sbjct: 265 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 324

Query: 305 RASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQ-EMLEKMQAQMQQSQAQGEQ 363
             ++ +L++           PLA  E+  RE   ++++M+ EM +  + ++++   + + 
Sbjct: 325 NKNKGQLTKS----------PLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKD 374

Query: 364 SDA 366
           S+A
Sbjct: 375 SEA 377


>gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]
          Length = 436

 Score =  349 bits (895), Expect = 3e-96
 Identities = 176/363 (48%), Positives = 257/363 (70%), Gaps = 16/363 (4%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           YVGFA LPNQ++RKSVK+GF+FTLMV GESGLGKSTLINSLFLT+LY   + P  S R+ 
Sbjct: 29  YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 87

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ +E+  V I+EGGV++ LT+VDTPGFGD+VD S+CW PV+ +I+ +FE YL  ES +
Sbjct: 88  KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147

Query: 125 NRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
           NR+ + D+RV CCLYFI+P G GL+PLD+ F++ +HEKVNIIP+I KAD L P+E Q  K
Sbjct: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207

Query: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
           ++I  +++E +I IY+FPE D +E+    +   ++K+ +P AVVGS  ++   G R VRG
Sbjct: 208 KQIMKEIQEHKIKIYEFPETDDEEENKLVK---KIKDRLPLAVVGSNTIIEVNGKR-VRG 263

Query: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARD 304
           R+Y WG  EVEN  HCDF  LR ML++TH+QDLK+VT+++ YE YR+R L ++   G  +
Sbjct: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323

Query: 305 RASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQ-EMLEKMQAQMQQSQAQGEQ 363
             ++ +L++           PLA  E+  RE   ++++M+ EM +  + ++++   + + 
Sbjct: 324 NKNKGQLTKS----------PLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKD 373

Query: 364 SDA 366
           S+A
Sbjct: 374 SEA 376


>gi|156602655 septin 3 isoform A [Homo sapiens]
          Length = 358

 Score =  278 bits (711), Expect = 6e-75
 Identities = 141/292 (48%), Positives = 200/292 (68%), Gaps = 5/292 (1%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           Y+G   +  Q+ +K++K GFDF +MV G+SGLGKSTL+N+LF + +           ++ 
Sbjct: 41  YIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIP 100

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ I+  G  IEEGGVK+KLT++DTPGFGD ++  +CW P+ K+I EQ+E++L++E  +
Sbjct: 101 KTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNI 160

Query: 125 NR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQAL 183
            R K I D+RVHCCLYFISP G  LRPLD+ F++ + + VNIIPVI KAD +  +E    
Sbjct: 161 ARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEF 220

Query: 184 KQKIRDQLKEEEIHIYQFPECDSDED-EDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
           KQ++R +L+   I  Y  P+ + DED ED    D   +ES+PFAVVGS +  +  G R V
Sbjct: 221 KQRVRKELEVNGIEFY--PQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKR-V 277

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
            GR+  WG +EVEN +HC+F  LR  +++THLQDLKEVTH++ YE YRA+ L
Sbjct: 278 LGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRL 329


>gi|156602653 septin 3 isoform B [Homo sapiens]
          Length = 350

 Score =  278 bits (711), Expect = 6e-75
 Identities = 141/292 (48%), Positives = 200/292 (68%), Gaps = 5/292 (1%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           Y+G   +  Q+ +K++K GFDF +MV G+SGLGKSTL+N+LF + +           ++ 
Sbjct: 41  YIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIP 100

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
           +T+ I+  G  IEEGGVK+KLT++DTPGFGD ++  +CW P+ K+I EQ+E++L++E  +
Sbjct: 101 KTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNI 160

Query: 125 NR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQAL 183
            R K I D+RVHCCLYFISP G  LRPLD+ F++ + + VNIIPVI KAD +  +E    
Sbjct: 161 ARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEF 220

Query: 184 KQKIRDQLKEEEIHIYQFPECDSDED-EDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
           KQ++R +L+   I  Y  P+ + DED ED    D   +ES+PFAVVGS +  +  G R V
Sbjct: 221 KQRVRKELEVNGIEFY--PQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKR-V 277

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
            GR+  WG +EVEN +HC+F  LR  +++THLQDLKEVTH++ YE YRA+ L
Sbjct: 278 LGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRL 329


>gi|164698504 septin 9 isoform f [Homo sapiens]
          Length = 335

 Score =  271 bits (694), Expect = 5e-73
 Identities = 133/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTLIN+LF + +      P + 
Sbjct: 23  VDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE 82

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R+ +T+ I+    +IEE GV++KLT++DTPGFGD ++  +CW P++KFI +Q+E+YL++
Sbjct: 83  ERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQE 142

Query: 121 ESGLNR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQE 179
           E  +NR K I D+RVHCCLYFI   G  LRPLD+ F++ + + VNI+PVI KAD L  +E
Sbjct: 143 EVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEE 202

Query: 180 TQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGN 239
               KQ+I   L    I +Y  P+ + DED + +  + + +E IPFAVVGS    +  G 
Sbjct: 203 RVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGK 260

Query: 240 RPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
           R + GR+  WGT+EVEN  HC+F  LR +L++TH+Q++K++T  + +E YR + L
Sbjct: 261 R-ILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 314


>gi|164698502 septin 9 isoform d [Homo sapiens]
          Length = 474

 Score =  271 bits (694), Expect = 5e-73
 Identities = 133/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTLIN+LF + +      P + 
Sbjct: 162 VDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE 221

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R+ +T+ I+    +IEE GV++KLT++DTPGFGD ++  +CW P++KFI +Q+E+YL++
Sbjct: 222 ERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQE 281

Query: 121 ESGLNR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQE 179
           E  +NR K I D+RVHCCLYFI   G  LRPLD+ F++ + + VNI+PVI KAD L  +E
Sbjct: 282 EVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEE 341

Query: 180 TQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGN 239
               KQ+I   L    I +Y  P+ + DED + +  + + +E IPFAVVGS    +  G 
Sbjct: 342 RVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGK 399

Query: 240 RPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
           R + GR+  WGT+EVEN  HC+F  LR +L++TH+Q++K++T  + +E YR + L
Sbjct: 400 R-ILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 453


>gi|164698500 septin 9 isoform e [Homo sapiens]
          Length = 422

 Score =  271 bits (694), Expect = 5e-73
 Identities = 133/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTLIN+LF + +      P + 
Sbjct: 110 VDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE 169

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R+ +T+ I+    +IEE GV++KLT++DTPGFGD ++  +CW P++KFI +Q+E+YL++
Sbjct: 170 ERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQE 229

Query: 121 ESGLNR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQE 179
           E  +NR K I D+RVHCCLYFI   G  LRPLD+ F++ + + VNI+PVI KAD L  +E
Sbjct: 230 EVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEE 289

Query: 180 TQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGN 239
               KQ+I   L    I +Y  P+ + DED + +  + + +E IPFAVVGS    +  G 
Sbjct: 290 RVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGK 347

Query: 240 RPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
           R + GR+  WGT+EVEN  HC+F  LR +L++TH+Q++K++T  + +E YR + L
Sbjct: 348 R-ILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 401


>gi|164698498 septin 9 isoform b [Homo sapiens]
          Length = 579

 Score =  271 bits (694), Expect = 5e-73
 Identities = 133/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTLIN+LF + +      P + 
Sbjct: 267 VDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE 326

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R+ +T+ I+    +IEE GV++KLT++DTPGFGD ++  +CW P++KFI +Q+E+YL++
Sbjct: 327 ERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQE 386

Query: 121 ESGLNR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQE 179
           E  +NR K I D+RVHCCLYFI   G  LRPLD+ F++ + + VNI+PVI KAD L  +E
Sbjct: 387 EVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEE 446

Query: 180 TQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGN 239
               KQ+I   L    I +Y  P+ + DED + +  + + +E IPFAVVGS    +  G 
Sbjct: 447 RVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGK 504

Query: 240 RPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
           R + GR+  WGT+EVEN  HC+F  LR +L++TH+Q++K++T  + +E YR + L
Sbjct: 505 R-ILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 558


>gi|164698496 septin 9 isoform e [Homo sapiens]
          Length = 422

 Score =  271 bits (694), Expect = 5e-73
 Identities = 133/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTLIN+LF + +      P + 
Sbjct: 110 VDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE 169

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R+ +T+ I+    +IEE GV++KLT++DTPGFGD ++  +CW P++KFI +Q+E+YL++
Sbjct: 170 ERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQE 229

Query: 121 ESGLNR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQE 179
           E  +NR K I D+RVHCCLYFI   G  LRPLD+ F++ + + VNI+PVI KAD L  +E
Sbjct: 230 EVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEE 289

Query: 180 TQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGN 239
               KQ+I   L    I +Y  P+ + DED + +  + + +E IPFAVVGS    +  G 
Sbjct: 290 RVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGK 347

Query: 240 RPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
           R + GR+  WGT+EVEN  HC+F  LR +L++TH+Q++K++T  + +E YR + L
Sbjct: 348 R-ILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 401


>gi|164698494 septin 9 isoform a [Homo sapiens]
          Length = 586

 Score =  271 bits (694), Expect = 5e-73
 Identities = 133/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTLIN+LF + +      P + 
Sbjct: 274 VDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE 333

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R+ +T+ I+    +IEE GV++KLT++DTPGFGD ++  +CW P++KFI +Q+E+YL++
Sbjct: 334 ERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQE 393

Query: 121 ESGLNR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQE 179
           E  +NR K I D+RVHCCLYFI   G  LRPLD+ F++ + + VNI+PVI KAD L  +E
Sbjct: 394 EVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEE 453

Query: 180 TQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGN 239
               KQ+I   L    I +Y  P+ + DED + +  + + +E IPFAVVGS    +  G 
Sbjct: 454 RVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGK 511

Query: 240 RPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
           R + GR+  WGT+EVEN  HC+F  LR +L++TH+Q++K++T  + +E YR + L
Sbjct: 512 R-ILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 565


>gi|116256489 septin 9 isoform c [Homo sapiens]
          Length = 568

 Score =  271 bits (694), Expect = 5e-73
 Identities = 133/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60
           +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTLIN+LF + +      P + 
Sbjct: 256 VDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE 315

Query: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120
            R+ +T+ I+    +IEE GV++KLT++DTPGFGD ++  +CW P++KFI +Q+E+YL++
Sbjct: 316 ERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQE 375

Query: 121 ESGLNR-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQE 179
           E  +NR K I D+RVHCCLYFI   G  LRPLD+ F++ + + VNI+PVI KAD L  +E
Sbjct: 376 EVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEE 435

Query: 180 TQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGN 239
               KQ+I   L    I +Y  P+ + DED + +  + + +E IPFAVVGS    +  G 
Sbjct: 436 RVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGK 493

Query: 240 RPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCL 294
           R + GR+  WGT+EVEN  HC+F  LR +L++TH+Q++K++T  + +E YR + L
Sbjct: 494 R-ILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 547


>gi|226492421 septin 12 isoform 2 [Homo sapiens]
          Length = 358

 Score =  253 bits (646), Expect = 2e-67
 Identities = 128/286 (44%), Positives = 196/286 (68%), Gaps = 5/286 (1%)

Query: 6   VGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLTQ 65
           VG  A+ +QL  K++K GF+F +MV G+SGLGKST++N+LF + +++    P       Q
Sbjct: 30  VGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNP-PGLGVPTPQ 88

Query: 66  TLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGLN 125
           TL +      IEE GVK+KLT+ DTPGFGD ++  +CW P++ +I EQ+EQYL++E  + 
Sbjct: 89  TLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILIT 148

Query: 126 R-KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
           R ++I D+RVHCC+YF+ P G  LRPLD+ FL+ +   VN++PVI +AD+L  +E +A +
Sbjct: 149 RQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFR 208

Query: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
           ++I+  L+   I +Y  P+   DED + K  ++++++ IPFAVVG+ +     G R V G
Sbjct: 209 RRIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNG-RCVLG 265

Query: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYR 290
           R+  WG +EVEN  HC+F  LR +L+++HLQDLK++TH++ YE YR
Sbjct: 266 RKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYR 311


>gi|8922712 septin 11 [Homo sapiens]
          Length = 429

 Score =  246 bits (628), Expect = 2e-65
 Identities = 141/360 (39%), Positives = 216/360 (60%), Gaps = 22/360 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           +VGF +LP+QL  KS  +GF F ++  GE+G+GKSTL+++LF T    D           
Sbjct: 21  HVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPG--- 77

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
             + ++ R  E++E  V++KLT+VDT GFGD ++  D + P+V++I+ QFE YL++E  +
Sbjct: 78  --VRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKI 135

Query: 125 NRK--NIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQA 182
            R   N  D+R+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KAD +   E   
Sbjct: 136 KRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHK 195

Query: 183 LKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
            K KI  +L    + IYQFP     ++E     +A M   +PFAVVGS E V+  GN+  
Sbjct: 196 FKSKIMSELVSNGVQIYQFP----TDEETVAEINATMSVHLPFAVVGSTEEVKI-GNKMA 250

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGA 302
           + R+Y WG V+VEN +HCDF+ LR ML++ +++DL+E TH   YE YR RC   L   G 
Sbjct: 251 KARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYR-RC--KLEEMGF 307

Query: 303 RDRASRSK-LSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEM-LEKMQAQMQQSQAQ 360
           +D    SK  S Q   E       L + +K    K+EE+R+M  M +++ +A++++++ +
Sbjct: 308 KDTDPDSKPFSLQETYEAKRNEF-LGELQK----KEEEMRQMFVMRVKEKEAELKEAEKE 362


>gi|30795193 septin 10 isoform 2 [Homo sapiens]
          Length = 431

 Score =  243 bits (621), Expect = 2e-64
 Identities = 137/354 (38%), Positives = 212/354 (59%), Gaps = 32/354 (9%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           +VGF +LP+QL  +S+++GF F ++  GE+G+GKSTLI++LF TN +ED +    S+   
Sbjct: 23  HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 77

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
             + ++ +  E++E  V++KLT+V+T GFGD ++  + + P+V +I+ QFE YL++E  +
Sbjct: 78  PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 137

Query: 125 NRK--NIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQA 182
            R      DSR+H CLYFISP G  L+ LD+  ++ +  KVNIIPVI KAD +   E Q 
Sbjct: 138 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 197

Query: 183 LKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
            K K+  +L    + IYQFP     +D+   + +A M   +PFAVVGS + V+  GN+ V
Sbjct: 198 FKIKLMSELVSNGVQIYQFP----TDDDTIAKVNAAMNGQLPFAVVGSMDEVK-VGNKMV 252

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGA 302
           + R+Y WG V+VEN +HCDF+ LR ML+ T+++DL+E TH   YE YR            
Sbjct: 253 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYR------------ 300

Query: 303 RDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDE---ELRRMQEMLEKMQAQ 353
                R KL     T++     P++  E    ++ E   E +R +E +++M  Q
Sbjct: 301 -----RCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQ 349


>gi|21945064 septin 10 isoform 1 [Homo sapiens]
          Length = 454

 Score =  243 bits (621), Expect = 2e-64
 Identities = 137/354 (38%), Positives = 212/354 (59%), Gaps = 32/354 (9%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           +VGF +LP+QL  +S+++GF F ++  GE+G+GKSTLI++LF TN +ED +    S+   
Sbjct: 46  HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 100

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
             + ++ +  E++E  V++KLT+V+T GFGD ++  + + P+V +I+ QFE YL++E  +
Sbjct: 101 PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 160

Query: 125 NRK--NIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQA 182
            R      DSR+H CLYFISP G  L+ LD+  ++ +  KVNIIPVI KAD +   E Q 
Sbjct: 161 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 220

Query: 183 LKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
            K K+  +L    + IYQFP     +D+   + +A M   +PFAVVGS + V+  GN+ V
Sbjct: 221 FKIKLMSELVSNGVQIYQFP----TDDDTIAKVNAAMNGQLPFAVVGSMDEVK-VGNKMV 275

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGA 302
           + R+Y WG V+VEN +HCDF+ LR ML+ T+++DL+E TH   YE YR            
Sbjct: 276 KARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYR------------ 323

Query: 303 RDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDE---ELRRMQEMLEKMQAQ 353
                R KL     T++     P++  E    ++ E   E +R +E +++M  Q
Sbjct: 324 -----RCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGERQRKEEEMKQMFVQ 372


>gi|21361478 septin 6 isoform B [Homo sapiens]
          Length = 434

 Score =  243 bits (619), Expect = 3e-64
 Identities = 141/360 (39%), Positives = 216/360 (60%), Gaps = 22/360 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           +VGF +LP+QL  KSV +GF F ++  GE+GLGKSTL+++LF T         E +    
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEG-----EPATHTQ 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
             + ++    +++E  V++KLT+V T GFGD ++  D + P+V+FI+ QFE YL++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 125 NR--KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQA 182
            R      DSR+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KADA+   E   
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 183 LKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
            K KI  +L    + IYQFP     +DE     +  M   +PFAV+GS E ++  GN+ +
Sbjct: 197 FKIKITSELVSNGVQIYQFP----TDDESVAEINGTMNAHLPFAVIGSTEELKI-GNKMM 251

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGA 302
           R R+Y WGTV+VEN  HCDF+ LR ML++ +++DL+E TH   YE YR RC   L   G 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYR-RC--KLEEMGF 308

Query: 303 RDRASRSK-LSRQSATEIPLPMLPLADTEKLIREKDEELRRM-QEMLEKMQAQMQQSQAQ 360
           +D    SK  S Q   E       L + +K    K+EE+R+M  + +++ +A++++++ +
Sbjct: 309 KDTDPDSKPFSLQETYEAKRNEF-LGELQK----KEEEMRQMFVQRVKEKEAELKEAEKE 363


>gi|22035581 septin 6 isoform D [Homo sapiens]
          Length = 429

 Score =  243 bits (619), Expect = 3e-64
 Identities = 141/360 (39%), Positives = 216/360 (60%), Gaps = 22/360 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           +VGF +LP+QL  KSV +GF F ++  GE+GLGKSTL+++LF T         E +    
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEG-----EPATHTQ 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
             + ++    +++E  V++KLT+V T GFGD ++  D + P+V+FI+ QFE YL++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 125 NR--KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQA 182
            R      DSR+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KADA+   E   
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 183 LKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
            K KI  +L    + IYQFP     +DE     +  M   +PFAV+GS E ++  GN+ +
Sbjct: 197 FKIKITSELVSNGVQIYQFP----TDDESVAEINGTMNAHLPFAVIGSTEELKI-GNKMM 251

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGA 302
           R R+Y WGTV+VEN  HCDF+ LR ML++ +++DL+E TH   YE YR RC   L   G 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYR-RC--KLEEMGF 308

Query: 303 RDRASRSK-LSRQSATEIPLPMLPLADTEKLIREKDEELRRM-QEMLEKMQAQMQQSQAQ 360
           +D    SK  S Q   E       L + +K    K+EE+R+M  + +++ +A++++++ +
Sbjct: 309 KDTDPDSKPFSLQETYEAKRNEF-LGELQK----KEEEMRQMFVQRVKEKEAELKEAEKE 363


>gi|22035579 septin 6 isoform A [Homo sapiens]
          Length = 427

 Score =  243 bits (619), Expect = 3e-64
 Identities = 141/360 (39%), Positives = 216/360 (60%), Gaps = 22/360 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           +VGF +LP+QL  KSV +GF F ++  GE+GLGKSTL+++LF T         E +    
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEG-----EPATHTQ 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
             + ++    +++E  V++KLT+V T GFGD ++  D + P+V+FI+ QFE YL++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 125 NR--KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQA 182
            R      DSR+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KADA+   E   
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 183 LKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
            K KI  +L    + IYQFP     +DE     +  M   +PFAV+GS E ++  GN+ +
Sbjct: 197 FKIKITSELVSNGVQIYQFP----TDDESVAEINGTMNAHLPFAVIGSTEELKI-GNKMM 251

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGA 302
           R R+Y WGTV+VEN  HCDF+ LR ML++ +++DL+E TH   YE YR RC   L   G 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYR-RC--KLEEMGF 308

Query: 303 RDRASRSK-LSRQSATEIPLPMLPLADTEKLIREKDEELRRM-QEMLEKMQAQMQQSQAQ 360
           +D    SK  S Q   E       L + +K    K+EE+R+M  + +++ +A++++++ +
Sbjct: 309 KDTDPDSKPFSLQETYEAKRNEF-LGELQK----KEEEMRQMFVQRVKEKEAELKEAEKE 363


>gi|22035577 septin 6 isoform A [Homo sapiens]
          Length = 427

 Score =  243 bits (619), Expect = 3e-64
 Identities = 141/360 (39%), Positives = 216/360 (60%), Gaps = 22/360 (6%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
           +VGF +LP+QL  KSV +GF F ++  GE+GLGKSTL+++LF T         E +    
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEG-----EPATHTQ 76

Query: 65  QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
             + ++    +++E  V++KLT+V T GFGD ++  D + P+V+FI+ QFE YL++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 125 NR--KNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQA 182
            R      DSR+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KADA+   E   
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 183 LKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPV 242
            K KI  +L    + IYQFP     +DE     +  M   +PFAV+GS E ++  GN+ +
Sbjct: 197 FKIKITSELVSNGVQIYQFP----TDDESVAEINGTMNAHLPFAVIGSTEELKI-GNKMM 251

Query: 243 RGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGA 302
           R R+Y WGTV+VEN  HCDF+ LR ML++ +++DL+E TH   YE YR RC   L   G 
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYR-RC--KLEEMGF 308

Query: 303 RDRASRSK-LSRQSATEIPLPMLPLADTEKLIREKDEELRRM-QEMLEKMQAQMQQSQAQ 360
           +D    SK  S Q   E       L + +K    K+EE+R+M  + +++ +A++++++ +
Sbjct: 309 KDTDPDSKPFSLQETYEAKRNEF-LGELQK----KEEEMRQMFVQRVKEKEAELKEAEKE 363


>gi|149363638 septin 8 isoform c [Homo sapiens]
          Length = 442

 Score =  242 bits (617), Expect = 4e-64
 Identities = 140/367 (38%), Positives = 215/367 (58%), Gaps = 29/367 (7%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLY-EDRQVPEASARL 63
           +VGF +LP+QL  KSV +GF F ++  GE+G+GKSTL+N+LF T    E+    EA  RL
Sbjct: 24  HVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEACVRL 83

Query: 64  TQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESG 123
                   +  +++E  V++KLT+VD  GFGD ++  + + P+V +I+ QFE YL++E  
Sbjct: 84  RP------QTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELK 137

Query: 124 LNRK--NIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQ 181
           + R   +  D+R+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KAD +   E  
Sbjct: 138 IRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELH 197

Query: 182 ALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRP 241
             K KI  +L    + IYQFP     +DE     +A M   +PFAVVGS E V+  GN+ 
Sbjct: 198 KFKIKIMGELVSNGVQIYQFP----TDDEAVAEINAVMNAHLPFAVVGSTEEVK-VGNKL 252

Query: 242 VRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSL---- 297
           VR R+Y WG V+VEN +HCDF+ LR ML++ +++DL+E TH   YE YR   L+ +    
Sbjct: 253 VRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQD 312

Query: 298 ----ARP-------GARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEM 346
               ++P        A+ +   S+L R+      + +  + +TE  ++EK+ EL    E 
Sbjct: 313 SDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEH 372

Query: 347 LEKMQAQ 353
           L+++  +
Sbjct: 373 LKRVHQE 379


>gi|149363689 septin 8 isoform a [Homo sapiens]
          Length = 483

 Score =  242 bits (617), Expect = 4e-64
 Identities = 140/367 (38%), Positives = 215/367 (58%), Gaps = 29/367 (7%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLY-EDRQVPEASARL 63
           +VGF +LP+QL  KSV +GF F ++  GE+G+GKSTL+N+LF T    E+    EA  RL
Sbjct: 24  HVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEACVRL 83

Query: 64  TQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESG 123
                   +  +++E  V++KLT+VD  GFGD ++  + + P+V +I+ QFE YL++E  
Sbjct: 84  RP------QTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELK 137

Query: 124 LNRK--NIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQ 181
           + R   +  D+R+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KAD +   E  
Sbjct: 138 IRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELH 197

Query: 182 ALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRP 241
             K KI  +L    + IYQFP     +DE     +A M   +PFAVVGS E V+  GN+ 
Sbjct: 198 KFKIKIMGELVSNGVQIYQFP----TDDEAVAEINAVMNAHLPFAVVGSTEEVK-VGNKL 252

Query: 242 VRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSL---- 297
           VR R+Y WG V+VEN +HCDF+ LR ML++ +++DL+E TH   YE YR   L+ +    
Sbjct: 253 VRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQD 312

Query: 298 ----ARP-------GARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEM 346
               ++P        A+ +   S+L R+      + +  + +TE  ++EK+ EL    E 
Sbjct: 313 SDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEH 372

Query: 347 LEKMQAQ 353
           L+++  +
Sbjct: 373 LKRVHQE 379


>gi|149363661 septin 8 isoform b [Homo sapiens]
          Length = 429

 Score =  242 bits (617), Expect = 4e-64
 Identities = 140/367 (38%), Positives = 215/367 (58%), Gaps = 29/367 (7%)

Query: 5   YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLY-EDRQVPEASARL 63
           +VGF +LP+QL  KSV +GF F ++  GE+G+GKSTL+N+LF T    E+    EA  RL
Sbjct: 24  HVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEACVRL 83

Query: 64  TQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESG 123
                   +  +++E  V++KLT+VD  GFGD ++  + + P+V +I+ QFE YL++E  
Sbjct: 84  RP------QTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELK 137

Query: 124 LNRK--NIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQ 181
           + R   +  D+R+H CLYFI+P G  L+ LD+  ++ +  KVNIIP+I KAD +   E  
Sbjct: 138 IRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELH 197

Query: 182 ALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRP 241
             K KI  +L    + IYQFP     +DE     +A M   +PFAVVGS E V+  GN+ 
Sbjct: 198 KFKIKIMGELVSNGVQIYQFP----TDDEAVAEINAVMNAHLPFAVVGSTEEVK-VGNKL 252

Query: 242 VRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSL---- 297
           VR R+Y WG V+VEN +HCDF+ LR ML++ +++DL+E TH   YE YR   L+ +    
Sbjct: 253 VRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQD 312

Query: 298 ----ARP-------GARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEM 346
               ++P        A+ +   S+L R+      + +  + +TE  ++EK+ EL    E 
Sbjct: 313 SDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEH 372

Query: 347 LEKMQAQ 353
           L+++  +
Sbjct: 373 LKRVHQE 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,325,981
Number of Sequences: 37866
Number of extensions: 588153
Number of successful extensions: 3758
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 3327
Number of HSP's gapped (non-prelim): 375
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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