Guide to the Human Genome
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Search of human proteins with 165932391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|165932391 family with sequence similarity 69, member A [Homo
sapiens]
         (428 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|165932391 family with sequence similarity 69, member A [Homo ...   883   0.0  
gi|224922839 hypothetical protein LOC138311 [Homo sapiens]            434   e-122
gi|195546915 hypothetical protein LOC125704 [Homo sapiens]             80   5e-15
gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo s...    32   1.4  
gi|93102379 low density lipoprotein-related protein 1B precursor...    31   2.5  
gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]         30   4.2  
gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo s...    30   5.5  
gi|126012573 low density lipoprotein-related protein 2 [Homo sap...    29   7.2  
gi|134268640 tectorin alpha precursor [Homo sapiens]                   29   9.4  

>gi|165932391 family with sequence similarity 69, member A [Homo
           sapiens]
          Length = 428

 Score =  883 bits (2281), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 1   MARSLCPGAWLRKPYYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCK 60
           MARSLCPGAWLRKPYYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCK
Sbjct: 1   MARSLCPGAWLRKPYYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCK 60

Query: 61  KIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQAL 120
           KIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQAL
Sbjct: 61  KIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQAL 120

Query: 121 HLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADG 180
           HLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADG
Sbjct: 121 HLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADG 180

Query: 181 DKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGIS 240
           DKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGIS
Sbjct: 181 DKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGIS 240

Query: 241 LPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNL 300
           LPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNL
Sbjct: 241 LPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNL 300

Query: 301 GYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQ 360
           GYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQ
Sbjct: 301 GYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQ 360

Query: 361 PNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWK 420
           PNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWK
Sbjct: 361 PNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWK 420

Query: 421 KISYTNDS 428
           KISYTNDS
Sbjct: 421 KISYTNDS 428


>gi|224922839 hypothetical protein LOC138311 [Homo sapiens]
          Length = 431

 Score =  434 bits (1117), Expect = e-122
 Identities = 199/412 (48%), Positives = 281/412 (68%)

Query: 17  LQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPA 76
           LQ R   +R++ +F +WL VF GSW++YV YS+Y+E CRG  C+ +ICD+Y+ G+I G  
Sbjct: 20  LQGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGHVCQVVICDQYRKGIISGSV 79

Query: 77  CNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVL 136
           C  LC    + +  CLS  P  Q+Y G+W +    +KC +E+ L     ++  PR+E+VL
Sbjct: 80  CQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVL 139

Query: 137 FDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWA 196
           FDKPTRGT++++F+EM  S  KA LGD  +L  LV  +L +AD +KD +VSL EAKS WA
Sbjct: 140 FDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNKDNRVSLAEAKSVWA 199

Query: 197 LLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRS 256
           LLQ NEFLL++ LQ+KEH  +L+G+CGDLY+ E V + + +  +LP ++   +P   + +
Sbjct: 200 LLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLLPPALQGA 259

Query: 257 MDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKI 316
           + Q   P+WP +AKIAIGLLEFVE++FHG YG F MC+T+  N+GY   YD KM D++++
Sbjct: 260 LQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQV 319

Query: 317 VPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLR 376
            PE  ++  ++ R CE   DC YG DCR  CD+   +C  ++IQPNLAK C LL+ YLL 
Sbjct: 320 APEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGDLIQPNLAKVCALLRGYLLP 379

Query: 377 GAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS 428
           GAP+++REEL  QL +C  L   A+Q+E  HSL+L++LKTLLWKKIS T  S
Sbjct: 380 GAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWKKISNTKYS 431


>gi|195546915 hypothetical protein LOC125704 [Homo sapiens]
          Length = 419

 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 84/346 (24%), Positives = 138/346 (39%), Gaps = 31/346 (8%)

Query: 30  FFSWLV--VFVGSWIIYVQYSTYTELCRGKDCKKII---CDKYKTGVIDGPACNSLCVTE 84
           F +W    V   + ++       +E C  +  ++I+   C  Y+ G + G  C  LCV  
Sbjct: 28  FAAWTAGWVLAAALLLRAHPGVLSERCTDEKSRRILAALCQDYQGGTLAGDLCEDLCVAG 87

Query: 85  TLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGT 144
            L F +CL      ++    W   P V+K + E        + LE        D P    
Sbjct: 88  ELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEEAFSSFPPLSLLEEEAGEGGQDMPEAEL 147

Query: 145 TVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEFL 204
            +     MV    K+ LG      EL N  L      + G    G+  S WALLQ  E++
Sbjct: 148 LL-----MVAGEVKSALG-----LELSNSSLGPWWPGRRGPRWRGQLASLWALLQQEEYV 197

Query: 205 LMVILQD-KEHTPKLMGFCGDLYVMESVEYTSLYGISL-PWVIELFIPSGFRRSMDQLFT 262
              +LQD   H   ++G CG  Y +E +   S +  +L P       P G +        
Sbjct: 198 YFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDRAPGAPGGGQAK------ 251

Query: 263 PSWPRKAKIAIGLLEFVEDVFHGPYGNFL-MCDTSAKNLGYNDKYDLKMVDMRKIVPETN 321
                 + IA+  L+ V   F   + + L +CD   +N      + +  +D+     E  
Sbjct: 252 ----AISDIALSFLDMVNH-FDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDMAFFEPK 306

Query: 322 LKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKAC 367
           ++E++ +++C  D DC +  DC + CD    KC ++ +  NL   C
Sbjct: 307 MREIL-EQNCTGDEDCNF-FDCFSRCDLRVNKCGAQRVNNNLQVIC 350


>gi|34452711 Ca2+-dependent secretion activator isoform 3 [Homo
           sapiens]
          Length = 1274

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 13/107 (12%)

Query: 144 TTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEF 203
           T ++K  E    +  ++L +   + E V  ++T A   +D              ++L E 
Sbjct: 819 TVIRKCLEQAALVNYSRLSEYAKIEENVGRLITPAKKLED-------------TIRLAEL 865

Query: 204 LLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIP 250
           ++ V+ Q++EH  +   +  DL V  +  + SL+ + +   +E+  P
Sbjct: 866 VIEVLQQNEEHHAEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPP 912


>gi|93102379 low density lipoprotein-related protein 1B precursor
            [Homo sapiens]
          Length = 4599

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 11/29 (37%), Positives = 17/29 (58%), Gaps = 3/29 (10%)

Query: 331  CESDLDCVYGTD---CRTSCDQSTMKCTS 356
            C+ D DC  G+D   C TSC +   +C++
Sbjct: 3534 CDGDFDCADGSDERNCETSCSKDQFRCSN 3562



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 3/30 (10%)

Query: 330  HCESDLDCVYGTD---CRTSCDQSTMKCTS 356
            HC+SD DC  G+D   C  SC  +  +C+S
Sbjct: 986  HCDSDDDCGDGSDEVGCVHSCFDNQFRCSS 1015


>gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]
          Length = 493

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 12/134 (8%)

Query: 257 MDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKI 316
           M QL   SW  + +I + L   +  + H P G+  + D   +     D  +LK+ D+   
Sbjct: 241 MIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVDG-ELKVTDLD-- 297

Query: 317 VPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMK--CTSEVIQPNLAKACQLLKDYL 374
                    +++  C    DC+     R      + +  C     + NL  A +    YL
Sbjct: 298 ------DARVEETPCAGSTDCILEFPARNFTLPCSAQGWCEGMNEKRNLYNAYRFFFTYL 351

Query: 375 L-RGAPSEIREELE 387
           L   AP  +R  L+
Sbjct: 352 LPHSAPPSLRPLLD 365


>gi|34452713 Ca2+-dependent secretion activator isoform 2 [Homo
           sapiens]
          Length = 1314

 Score = 29.6 bits (65), Expect = 5.5
 Identities = 15/60 (25%), Positives = 31/60 (51%)

Query: 191 AKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIP 250
           AK     ++L E ++ V+ Q++EH  +   +  DL V  +  + SL+ + +   +E+  P
Sbjct: 893 AKKLEDTIRLAELVIEVLQQNEEHHAEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPP 952


>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
          Length = 4655

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 3/29 (10%)

Query: 331  CESDLDCVYGTD---CRTSCDQSTMKCTS 356
            C+ D DCV G+D   C  +C  S  KC S
Sbjct: 1168 CDGDKDCVDGSDEVGCVLNCTASQFKCAS 1196



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 14/29 (48%), Positives = 17/29 (58%), Gaps = 2/29 (6%)

Query: 331 CESDLDCVYGTDCRTSCDQSTMKCTSEVI 359
           C+ D DC  G+D R  C QST  C+S  I
Sbjct: 87  CDQDQDCDDGSDERQDCSQST--CSSHQI 113


>gi|134268640 tectorin alpha precursor [Homo sapiens]
          Length = 2155

 Score = 28.9 bits (63), Expect = 9.4
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 64   CDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIW 105
            C++  T  +DGP C+  CVT TL          N+ M L +W
Sbjct: 2094 CEQICTSRVDGPLCS--CVTGTLQEDGKSCRASNSSMELQVW 2133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,626,325
Number of Sequences: 37866
Number of extensions: 726843
Number of successful extensions: 1564
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1548
Number of HSP's gapped (non-prelim): 18
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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