Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 157694526
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157694526 Fc receptor-like 5 [Homo sapiens]
(977 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157694526 Fc receptor-like 5 [Homo sapiens] 1974 0.0
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens] 452 e-127
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens] 319 7e-87
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 293 4e-79
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens] 242 1e-63
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens] 240 4e-63
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens] 207 4e-53
gi|50878302 Fc receptor-like B [Homo sapiens] 166 1e-40
gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64... 157 5e-38
gi|157057547 Fc receptor-like 6 [Homo sapiens] 133 7e-31
gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens] 124 6e-28
gi|110349719 titin isoform N2-A [Homo sapiens] 113 1e-24
gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isofo... 112 2e-24
gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isofo... 112 2e-24
gi|118572606 hemicentin 1 [Homo sapiens] 112 2e-24
gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Hom... 111 3e-24
gi|132814489 low affinity immunoglobulin gamma Fc region recepto... 110 6e-24
gi|110347451 platelet/endothelial cell adhesion molecule [Homo s... 109 1e-23
gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isofo... 108 3e-23
gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isofo... 108 3e-23
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 107 4e-23
gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor (CD... 107 7e-23
gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor (CD... 107 7e-23
gi|189083836 Fc fragment of IgG, low affinity IIIa, receptor (CD... 107 7e-23
gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD1... 107 7e-23
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 107 7e-23
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 107 7e-23
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 107 7e-23
gi|189083842 Fc fragment of IgG, low affinity IIIa, receptor (CD... 106 1e-22
gi|4503675 Fc fragment of IgE, high affinity I, receptor for; al... 103 8e-22
>gi|157694526 Fc receptor-like 5 [Homo sapiens]
Length = 977
Score = 1974 bits (5115), Expect = 0.0
Identities = 977/977 (100%), Positives = 977/977 (100%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR
Sbjct: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
Query: 61 YLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVV 120
YLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVV
Sbjct: 61 YLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVV 120
Query: 121 LRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNT 180
LRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNT
Sbjct: 121 LRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNT 180
Query: 181 VKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWS 240
VKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWS
Sbjct: 181 VKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWS 240
Query: 241 LSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFE 300
LSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFE
Sbjct: 241 LSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFE 300
Query: 301 GTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNG 360
GTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNG
Sbjct: 301 GTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNG 360
Query: 361 LGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAA 420
LGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAA
Sbjct: 361 LGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAA 420
Query: 421 LERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSA 480
LERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSA
Sbjct: 421 LERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSA 480
Query: 481 EALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYY 540
EALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYY
Sbjct: 481 EALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYY 540
Query: 541 CTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWF 600
CTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWF
Sbjct: 541 CTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWF 600
Query: 601 YHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPI 660
YHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPI
Sbjct: 601 YHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPI 660
Query: 661 LTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTE 720
LTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTE
Sbjct: 661 LTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTE 720
Query: 721 HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSP 780
HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSP
Sbjct: 721 HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSP 780
Query: 781 LILYRFFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGL 840
LILYRFFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGL
Sbjct: 781 LILYRFFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGL 840
Query: 841 TANRSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYH 900
TANRSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYH
Sbjct: 841 TANRSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYH 900
Query: 901 NVPAWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVA 960
NVPAWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVA
Sbjct: 901 NVPAWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVA 960
Query: 961 STPVSGSLFLASSAPHR 977
STPVSGSLFLASSAPHR
Sbjct: 961 STPVSGSLFLASSAPHR 977
>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
Length = 734
Score = 452 bits (1163), Expect = e-127
Identities = 257/567 (45%), Positives = 332/567 (58%), Gaps = 11/567 (1%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ-KTKWYH 59
MLLW++LL+L P Q P+ ++ L PPW+T F+GE+V L C Q T WYH
Sbjct: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
Query: 60 RYLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSV 119
+++L+ D I ++ E G Y+C+ +GS LS VH++FS LILQA VFEGD+V
Sbjct: 61 ---DEKLLKIKHDKI-QITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNV 116
Query: 120 VLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCC---PV 176
+LRC+ K + +Y D + + ++ +DN Y CT Y++ V
Sbjct: 117 ILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEV 176
Query: 177 SSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLG 236
+S + IQVQE F PVLRASS PI G+P+TLTCETQLS +R DV L+F FRD QTLG
Sbjct: 177 TSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLG 236
Query: 237 LGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQ-IPASHPVLTLSPEK 295
LGWS SP QI AMW++DSG YWC+ T+ +S+ S RS I+VQ +P S+ L + P
Sbjct: 237 LGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTG 296
Query: 296 ALNFEGTKVTLHCETQEDSLRTLYRFYHEG--VPLRHKSVRCERGASISFSLTTENSGNY 353
EG + L C + S + ++ EG L K+ R ++ ++G Y
Sbjct: 297 GQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRY 356
Query: 354 YCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQ 413
YC ADN S + ++V +PVSHPVL +P G + LHCE+ RGS PILY+
Sbjct: 357 YCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYR 416
Query: 414 FHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHP 473
F+HE L SA S GG + + SLTAEHSGNY C ADNG G Q S VSL VTVPVS P
Sbjct: 417 FYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRP 476
Query: 474 VLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTE 533
VLTL + A G + LHCE RGS ILY FYHED L + S S G SF+ SLT
Sbjct: 477 VLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTT 536
Query: 534 GHSGNYYCTADNGFGPQRSEVVSLFVT 560
HSGNY C ADNG G Q S+VV+L VT
Sbjct: 537 EHSGNYSCEADNGLGAQHSKVVTLNVT 563
Score = 420 bits (1079), Expect = e-117
Identities = 294/711 (41%), Positives = 383/711 (53%), Gaps = 70/711 (9%)
Query: 284 ASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRF-YHEGVPLRHKSVRCERGASIS 342
A VL L+P + F+G KV L C + SL + YH+ L+ K + +
Sbjct: 20 APKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYHDEKLLKIKHDKIQ------ 73
Query: 343 FSLTTENSGNYYCTADNGLGAKPSKAVSLSVT-----VPVSHPVLNLSSPEDLIFEGAKV 397
GNY C G+ S AV + + + HPV FEG V
Sbjct: 74 ----ITEPGNYQCKTR---GSSLSDAVHVEFSPDWLILQALHPV----------FEGDNV 116
Query: 398 TLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFG-- 455
L C+ + ++ +G L NS I+ + + + Y+CTA F
Sbjct: 117 ILRCQGKDNKNTHQKVYYKDGKQLP----NSYNLEKITVNSVSRDNSKYHCTAYRKFYIL 172
Query: 456 --PQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQ----RGSPQILYQFYH 509
SK +++ V HPVL SS+ + EG+ +TL CE Q R Q+ + +
Sbjct: 173 DIEVTSKPLNIQVQELFLHPVLRASSSTPI--EGSPMTLTCETQLSPQRPDVQLQFSLFR 230
Query: 510 EDMPL---WSSSTPSVGRVSFSFSLTEGHSGNYYC---TADNGFGPQRSEVVSLFVTVPV 563
+ L WS S R+ TE SG+Y+C T + + VPV
Sbjct: 231 DSQTLGLGWSRSP----RLQIPAMWTED-SGSYWCEVETVTHSIKKRSLRSQIRVQRVPV 285
Query: 564 SRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDV--TLGSSSAPSGGEASFN 621
S L +R Q + G+ + L C +GS + + ++ E +LG + S
Sbjct: 286 SNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHV 345
Query: 622 LSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCE 681
L++ +G Y C A+N S I ++V +PVS P+LTFRAPRA VVGDLLELHCE
Sbjct: 346 LTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCE 405
Query: 682 ALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMV 741
+LRGS PILY FYHEDVTLG SAPSGGGASFNLSLT EHSG YSC+ADNGL AQ S V
Sbjct: 406 SLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGV 465
Query: 742 TLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPS- 800
+L+V VPVSRPVLTLRAPG A VGDLLELHCE+LRGS ILY F+HED TLGN S+ S
Sbjct: 466 SLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSG 525
Query: 801 GGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIA 860
GGAS NLSLT EHSGNYSCEADNGLGAQ S+ VTL +TG + NR+G A G+ G +LSI
Sbjct: 526 GGASFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSIL 585
Query: 861 GLAAGALLL-YCWLSRKAGRKPAS-----------DPARS-PSDSDSQEPTYHNVPAWEE 907
LAA A LL Y RK G A+ +P+ S PS D QEPT+ A E
Sbjct: 586 VLAAAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPME 645
Query: 908 LQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVK 958
L+P+Y+N NP N +YS++ IQ K+++ H ++ ++YSE+K
Sbjct: 646 LEPMYSNVNPGDSNPIYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELK 696
Score = 371 bits (953), Expect = e-102
Identities = 237/537 (44%), Positives = 308/537 (57%), Gaps = 36/537 (6%)
Query: 254 DSGFYWCKA--ATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQ 311
+ G Y CK +++ +V + W+ +Q A HPV FEG V L C+ +
Sbjct: 76 EPGNYQCKTRGSSLSDAVHVEFSPDWLILQ--ALHPV----------FEGDNVILRCQGK 123
Query: 312 EDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSL 371
++ +Y +G L + S E+ I+ + + ++ Y+CTA + S
Sbjct: 124 DNKNTHQKVYYKDGKQLPN-SYNLEK---ITVNSVSRDNSKYHCTAYRKFYILDIEVTSK 179
Query: 372 SVTVPVS----HPVLNLSSPEDLIFEGAKVTLHCEAQ----RGSLPILYQFHHEGAALER 423
+ + V HPVL SS + EG+ +TL CE Q R + + + + L
Sbjct: 180 PLNIQVQELFLHPVLRASSSTPI--EGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGL 237
Query: 424 RSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTV---PVSHPVLTLSSA 480
+ S + I ++ E SG+Y+C + + +++ + V PVS+ L +
Sbjct: 238 GWSRSPR-LQIP-AMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPT 295
Query: 481 EALTFEGATVTLHCEVQRGSPQILYQFYHEDM--PLWSSSTPSVGRVSFSFSLTEGHSGN 538
EG + L C V +GS + + ++ E L + S+ ++ E +G
Sbjct: 296 GGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGR 355
Query: 539 YYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILY 598
YYC ADN P S + + V +PVS P+LT R PRA VVGDLLELHCE+ RGSPPILY
Sbjct: 356 YYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILY 415
Query: 599 WFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSR 658
FYHEDVTLG+SSAPSGG ASFNLSLTAEHSGNYSC+A+NGL AQHS +SL V VPVSR
Sbjct: 416 RFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSR 475
Query: 659 PILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLT 718
P+LT RAP AQAVVGDLLELHCE+LRGS PILYWFYHED TLG ISA SGGGASFNLSLT
Sbjct: 476 PVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLT 535
Query: 719 TEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEA 775
TEHSG YSCEADNGL AQ S++VTL V SR L A G V +L L A
Sbjct: 536 TEHSGNYSCEADNGLGAQHSKVVTLNV-TGTSRNRTGLTAAGITGLVLSILVLAAAA 591
>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
Length = 515
Score = 319 bits (818), Expect = 7e-87
Identities = 177/379 (46%), Positives = 226/379 (59%), Gaps = 6/379 (1%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW LL APV GQ A +P+I + PPWTT F+GERVTLTC GF+FY+ +KT WYHR
Sbjct: 1 MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHR 60
Query: 61 YLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVV 120
+ E L TP N LEV+ESG YRCQA+GSP S+PV L FSS SLILQAP SVFEGD++V
Sbjct: 61 HYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLV 120
Query: 121 LRCRAKAEVTLNNTIYK-NDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSN 179
LRC + + L Y N N+L+ NK D IP A +NG YRC GY + SN
Sbjct: 121 LRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSN 180
Query: 180 TVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGW 239
I++QE F P L+A+ QP GN V L+CETQL ERSD PL F FFRD + + W
Sbjct: 181 FKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDW 240
Query: 240 SLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQ-IPASHPVLTLSPEKALN 298
S P Q+ +W ++SG YWC A T+ ++ SP I VQ IP S +L P
Sbjct: 241 STYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQA 300
Query: 299 FEGTKVTLHCETQEDSLRTLYRFYHEGV--PLRHKSVRCERGASISFSLTTENSGNYYCT 356
EG + L C E + T + ++ E + L K+ R R ++ ++G YYCT
Sbjct: 301 VEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCT 360
Query: 357 ADNGLGAKPSKAVSLSVTV 375
ADN G P +++ L+VTV
Sbjct: 361 ADNSYG--PVQSMVLNVTV 377
Score = 129 bits (324), Expect = 1e-29
Identities = 142/508 (27%), Positives = 220/508 (43%), Gaps = 55/508 (10%)
Query: 473 PVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFS--FS 530
PV+++ F+G VTL C +QFY + W +++ + +
Sbjct: 23 PVISVHPPWTTFFKGERVTLTCNG--------FQFYATEKTTWYHRHYWGEKLTLTPGNT 74
Query: 531 LTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAP 590
L SG Y C A G RS V L S L L+ P + GD L L C
Sbjct: 75 LEVRESGLYRCQAR---GSPRSNPVRLLF----SSDSLILQAPYS-VFEGDTLVLRCHRR 126
Query: 591 RGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSL---TAEHSGNYSCEA---NNGLVAQH 644
R + L S+ S++L + ++ ++GNY C N + +
Sbjct: 127 RKEKLTAVKYTWNGNILSISNK------SWDLLIPQASSNNNGNYRCIGYGDENDVFRSN 180
Query: 645 SDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEAL----RGSSPILYWFYHE-DVT 699
I + + P P L +A +Q G+ + L CE R +P+ + F+ + +V
Sbjct: 181 FKIIKIQELFP--HPEL--KATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVI 236
Query: 700 LGKISAPSGGGASFNLSLTT---EHSGIYSCEADN--GLEAQRSEMVTLKVA-VPVSRPV 753
L S L L T E+SG Y C A+ G + S + + V +PVS +
Sbjct: 237 LSDWSTYP------ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVL 290
Query: 754 LTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDV--TLGNRSSPSGGASLNL-SLT 810
L + G A G++L L C G+ + + ED+ +LG ++ S A L L ++
Sbjct: 291 LETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIR 350
Query: 811 AEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIAGLAAGALLLY 870
H+G Y C ADN G +S + + + NR G A G GGLLS A L A ALL +
Sbjct: 351 QSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLS-ALLLAVALLFH 409
Query: 871 CWLSRKAGRKPASDPARSPSDSDSQEPTYHNVPAWEELQPVYTNANPRGENVVYSEVRII 930
CW RK+G D R P E ++ PA ELQ +Y + +P+ ++VYSE++
Sbjct: 410 CWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTT 469
Query: 931 QEKKKHAVASDPRHLRNKGSPIIYSEVK 958
Q ++ + L +K ++YSEVK
Sbjct: 470 QLGEEEEANTSRTLLEDKDVSVVYSEVK 497
Score = 87.0 bits (214), Expect = 8e-17
Identities = 95/375 (25%), Positives = 156/375 (41%), Gaps = 53/375 (14%)
Query: 204 GNPVTLTCETQLSLERSDVPLRFRFFRDDQTL-------GLGWSLSPNFQITAMWSKDSG 256
G VTLTC F+F+ ++T G +L+P + ++SG
Sbjct: 37 GERVTLTCNG------------FQFYATEKTTWYHRHYWGEKLTLTPGNTLEV---RESG 81
Query: 257 FYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLR 316
Y C+A SPRS + +S ++ +P FEG + L C +
Sbjct: 82 LYRCQAR--------GSPRSNPVRLLFSSDSLILQAPYSV--FEGDTLVLRCHRRRKEKL 131
Query: 317 TLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTA---DNGLGAKPSKAVSLSV 373
T ++ G L S+ + + ++ N+GNY C +N + K + +
Sbjct: 132 TAVKYTWNGNIL---SISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQE 188
Query: 374 TVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQ----RGSLPILYQFHHEGAALERRSANSA 429
P HP L + + EG V L CE Q R P+ + F +G + S S
Sbjct: 189 LFP--HPELKATDSQPT--EGNSVNLSCETQLPPERSDTPLHFNFFRDGEVI--LSDWST 242
Query: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTV---PVSHPVLTLSSAEALTFE 486
++ E+SG+Y+C A+ G + SL + V PVS +L + E
Sbjct: 243 YPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVE 302
Query: 487 GATVTLHCEVQRGSPQILYQFYHEDM--PLWSSSTPSVGRVSFSFSLTEGHSGNYYCTAD 544
G + L C V G+ + ++ EDM L + S+ ++ + H+G YYCTAD
Sbjct: 303 GEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTAD 362
Query: 545 NGFGPQRSEVVSLFV 559
N +GP +S V+++ V
Sbjct: 363 NSYGPVQSMVLNVTV 377
Score = 83.2 bits (204), Expect = 1e-15
Identities = 95/389 (24%), Positives = 159/389 (40%), Gaps = 57/389 (14%)
Query: 380 PVLNLSSPEDLIFEGAKVTLHC---EAQRGSLPILYQFHHEGAALERRSANSAGGVAISF 436
PV+++ P F+G +VTL C + Y H+ G L N
Sbjct: 23 PVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGN--------- 73
Query: 437 SLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEAL-------TFEGAT 489
+L SG Y C A P S+PV L S+++L FEG T
Sbjct: 74 TLEVRESGLYRCQARGS---------------PRSNPVRLLFSSDSLILQAPYSVFEGDT 118
Query: 490 VTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHS---GNYYCTADNG 546
+ L C +R ++ W+ + S+ S+ + + S GNY C G
Sbjct: 119 LVLRCHRRRKEKLTAVKY------TWNGNILSISNKSWDLLIPQASSNNNGNYRCI---G 169
Query: 547 FGPQRSEVVSLFVTVPVSR--PILTLRVPRAQAVVGDLLELHCEA---PRGSPPILYWFY 601
+G + S F + + P L+ +Q G+ + L CE P S L++ +
Sbjct: 170 YGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNF 229
Query: 602 HEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSC--EANNGLVAQHSDTISLSV-IVPVSR 658
D + S + E ++ E+SG+Y C E G + +HS ++ + V +PVS
Sbjct: 230 FRDGEVILSDWSTYPELQLP-TVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSG 288
Query: 659 PILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDV--TLGKISAPSGGGASFNLS 716
+L + QAV G++L L C G+ + ++ ED+ +LG+ + S +
Sbjct: 289 VLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPA 348
Query: 717 LTTEHSGIYSCEADNGLEAQRSEMVTLKV 745
+ H+G Y C ADN +S ++ + V
Sbjct: 349 IRQSHAGGYYCTADNSYGPVQSMVLNVTV 377
Score = 68.6 bits (166), Expect = 3e-11
Identities = 78/324 (24%), Positives = 135/324 (41%), Gaps = 38/324 (11%)
Query: 158 LKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSL 217
++++G YRC SN V++ ++ + + G+ + L C +
Sbjct: 77 VRESGLYRCQARGSP----RSNPVRLLFSSD---SLILQAPYSVFEGDTLVLRCHRR--- 126
Query: 218 ERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRS- 276
R + ++ + L + + S + I S ++G Y C + Y +D RS
Sbjct: 127 -RKEKLTAVKYTWNGNILSIS-NKSWDLLIPQASSNNNGNYRC----IGYGDENDVFRSN 180
Query: 277 --WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRT----LYRFYHEGVPLRH 330
I++Q HP L + + EG V L CETQ R+ + F+ +G
Sbjct: 181 FKIIKIQELFPHPELKATDSQPT--EGNSVNLSCETQLPPERSDTPLHFNFFRDG----- 233
Query: 331 KSVRCERGASISFSLTT---ENSGNYYCTADNGLGAKPSKAVSLSVTV---PVSHPVLNL 384
+ + + L T ENSG+Y+C A+ G + SL + V PVS +L
Sbjct: 234 EVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLET 293
Query: 385 SSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGA--ALERRSANSAGGVAISFSLTAEH 442
EG + L C G+ + +H E +L R++ S ++ H
Sbjct: 294 QPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSH 353
Query: 443 SGNYYCTADNGFGPQRSKAVSLSV 466
+G YYCTADN +GP +S ++++V
Sbjct: 354 AGGYYCTADNSYGPVQSMVLNVTV 377
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 293 bits (751), Expect = 4e-79
Identities = 172/371 (46%), Positives = 221/371 (59%), Gaps = 5/371 (1%)
Query: 104 SLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNV-LAFLNKRTDFHIPHACLKDNG 162
SL L AP SVFEGDS+VL+C+ + + Y DN L+ K +DF I A L D+G
Sbjct: 19 SLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDSG 78
Query: 163 AYRC-TGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSD 221
Y C T + +SN VKI+VQE F RPVL ASSFQPI G PV+L CET+LS +R D
Sbjct: 79 NYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLD 138
Query: 222 VPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQ 281
V L+F FFR++Q LG GWS SP QI+A+WS+D+G YWCKA T+ + + S +S I VQ
Sbjct: 139 VQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQ 198
Query: 282 -IPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHE--GVPLRHKSVRCERG 338
IP S+ L + EG K+ L C + + +Y E G + K+ R
Sbjct: 199 RIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSA 258
Query: 339 ASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVT 398
++ ++G YYC ADNG SK V++ V +PVS PVL L SP G +
Sbjct: 259 ELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLE 318
Query: 399 LHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQR 458
LHCEA RGS PILYQF+HE L SA S GG + + SLTAEHSGNY C A+NG G Q
Sbjct: 319 LHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQC 378
Query: 459 SKAVSLSVTVP 469
S+AV +S++ P
Sbjct: 379 SEAVPVSISGP 389
Score = 275 bits (703), Expect = 2e-73
Identities = 197/499 (39%), Positives = 265/499 (53%), Gaps = 36/499 (7%)
Query: 480 AEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSF---SLTEGHS 536
A + FEG ++ L C+ ++ +I YH+D + SV + F S S
Sbjct: 24 APSSVFEGDSIVLKCQGEQNW-KIQKMAYHKD-----NKELSVFKKFSDFLIQSAVLSDS 77
Query: 537 GNYYCTADNGF--GPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSP 594
GNY+C+ + S +V + V RP+LT Q + G + L CE R SP
Sbjct: 78 GNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLT--ASSFQPIEGGPVSLKCET-RLSP 134
Query: 595 PIL-----YWFYHEDVTLGSSSAPSGGEASFNLSLTA---EHSGNYSCEANNGLVAQHSD 646
L + F+ E+ LGS G +S L ++A E +G+Y C+A
Sbjct: 135 QRLDVQLQFCFFRENQVLGS-----GWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQ 189
Query: 647 TISLSVIV---PVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHE--DVTLG 701
++ + V P+S L RAP Q G L L C G+ + + +Y E ++G
Sbjct: 190 SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMG 249
Query: 702 KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGT 761
K + S ++ +G Y C ADNG +S++V + V +PVSRPVLTLR+PG
Sbjct: 250 KKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGA 309
Query: 762 HAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPSGG-ASLNLSLTAEHSGNYSCE 820
AAVGDLLELHCEALRGSP ILY+F+HEDVTLGN S+PSGG AS NLSLTAEHSGNYSCE
Sbjct: 310 QAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCE 369
Query: 821 ADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRK 880
A+NGLGAQ SE V + I+G R GV GL + G ALLLY + +G
Sbjct: 370 ANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLLYALFHKISGES 429
Query: 881 PASDPARSPSDSDSQEPTYHN-VPAWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVA 939
A++ R S + QE TY + P EELQPVY N +VVYS+V +Q+ + + A
Sbjct: 430 SATNEPRGASRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSMQQPE--SSA 487
Query: 940 SDPRHLRNKGSPIIYSEVK 958
+ L NK S +IYS VK
Sbjct: 488 NIRTLLENKDSQVIYSSVK 506
Score = 226 bits (576), Expect = 8e-59
Identities = 147/368 (39%), Positives = 207/368 (56%), Gaps = 18/368 (4%)
Query: 299 FEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTAD 358
FEG + L C+ +++ ++ + L SV + + S +SGNY+C+
Sbjct: 29 FEGDSIVLKCQGEQNWKIQKMAYHKDNKEL---SVFKKFSDFLIQSAVLSDSGNYFCSTK 85
Query: 359 NGLGA--KPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEA----QRGSLPILY 412
L K S V + V PVL SS + + EG V+L CE QR + + +
Sbjct: 86 GQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI--EGGPVSLKCETRLSPQRLDVQLQF 143
Query: 413 QFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTV---P 469
F E L +S+ + IS ++ +E +G+Y+C A+ R +++ + V P
Sbjct: 144 CFFRENQVLGS-GWSSSPELQIS-AVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIP 201
Query: 470 VSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHE--DMPLWSSSTPSVGRVSF 527
+S+ L + + EG + L C V G+ + + +Y E + + S+
Sbjct: 202 ISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELE 261
Query: 528 SFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHC 587
++ E +G YYC ADNG P +S+VV++ V +PVSRP+LTLR P AQA VGDLLELHC
Sbjct: 262 IPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHC 321
Query: 588 EAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDT 647
EA RGSPPILY FYHEDVTLG+SSAPSGG ASFNLSLTAEHSGNYSCEANNGL AQ S+
Sbjct: 322 EALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEA 381
Query: 648 ISLSVIVP 655
+ +S+ P
Sbjct: 382 VPVSISGP 389
Score = 218 bits (556), Expect = 2e-56
Identities = 162/437 (37%), Positives = 220/437 (50%), Gaps = 31/437 (7%)
Query: 382 LNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAE 441
L L +P +FEG + L C+ ++ +H + L S + S
Sbjct: 20 LTLVAPSS-VFEGDSIVLKCQGEQNWKIQKMAYHKDNKEL---SVFKKFSDFLIQSAVLS 75
Query: 442 HSGNYYCTADNGF--GPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEV--- 496
SGNY+C+ + S V + V PVLT SS + + EG V+L CE
Sbjct: 76 DSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPI--EGGPVSLKCETRLS 133
Query: 497 -QRGSPQILYQFYHEDMPLWS--SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSE 553
QR Q+ + F+ E+ L S SS+P + ++S +S +G+Y+C A+ R +
Sbjct: 134 PQRLDVQLQFCFFRENQVLGSGWSSSPEL-QISAVWS---EDTGSYWCKAETVTHRIRKQ 189
Query: 554 VVSLFVTV---PVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSS 610
+ + V P+S L +R P Q G L L C G+ + + +Y E T S
Sbjct: 190 SLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYRE-ATGTSM 248
Query: 611 SAPSGGEASFNLSLTA---EHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPR 667
+ S L + A +G Y C A+NG V S +++ V +PVSRP+LT R+P
Sbjct: 249 GKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPG 308
Query: 668 AQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSC 727
AQA VGDLLELHCEALRGS PILY FYHEDVTLG SAPSGGGASFNLSLT EHSG YSC
Sbjct: 309 AQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSC 368
Query: 728 EADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFF 787
EA+NGL AQ SE V + ++ P + A G L G L+LY F
Sbjct: 369 EANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVL------GFTGVALLLYALF 422
Query: 788 HEDVTLGNRSSPSGGAS 804
H+ + ++ GAS
Sbjct: 423 HKISGESSATNEPRGAS 439
Score = 126 bits (316), Expect = 1e-28
Identities = 115/401 (28%), Positives = 184/401 (45%), Gaps = 37/401 (9%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW +L++ V+ Q + L P ++VF+G+ + L C+G + + QK ++
Sbjct: 1 MLLWSLLVIFDAVTEQ-----ADSLTLVAP-SSVFEGDSIVLKCQGEQNWKIQKMAYHKD 54
Query: 61 YLGKEILRETPDNILE---VQESGEYRCQAQG-----SPLSSPVHL---DFSSASLILQA 109
+ ++ D +++ + +SG Y C +G S+ V + + ++ +
Sbjct: 55 NKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
Query: 110 PLSVFEGDSVVLRCRA-----KAEVTLNNTIYKNDNVL-AFLNKRTDFHIPHACLKDNGA 163
EG V L+C + +V L ++ + VL + + + I +D G+
Sbjct: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGS 174
Query: 164 YRCTGYKES-CCPVSSNTVKIQVQE-PFTRPVL--RASSFQPISGNPVTLTCETQLSLER 219
Y C + S +I VQ P + L RA Q G + L C S+
Sbjct: 175 YWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC----SVAG 230
Query: 220 SDVPLRFRFFRDDQTLGLG----WSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPR 275
+ F ++R+ +G SLS +I A+ D+G Y+C+A + S
Sbjct: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
Query: 276 SWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRC 335
I V+IP S PVLTL A G + LHCE S LY+FYHE V L + S
Sbjct: 291 --IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPS 348
Query: 336 ERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVP 376
GAS + SLT E+SGNY C A+NGLGA+ S+AV +S++ P
Sbjct: 349 GGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGP 389
>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
Length = 428
Score = 242 bits (617), Expect = 1e-63
Identities = 169/418 (40%), Positives = 222/418 (53%), Gaps = 19/418 (4%)
Query: 557 LFVTVPVSRPI-LTLRVPRAQAVVGDLLELHCEAP---RGSPPILYWFYHEDVTLGSSSA 612
L + P+ P L L + G + L C+ P + F+ + LG
Sbjct: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP--- 63
Query: 613 PSGGEASFNLSLTA---EHSGNYSCEAN---NGLVAQHSDTISLSVIVPVSRPILTFRAP 666
G +S L + A E +G+Y CEA + ++ I++ VPV+ L + P
Sbjct: 64 --GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHR-VPVADVSLETQPP 120
Query: 667 RAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGG-GASFNL-SLTTEHSGI 724
Q + GD L L C G+ I + +Y V L S A + + S+ +
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 725 YSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILY 784
Y C A+NG S +V++ V +PVSRP+L LRAP AAV D+LELHCEALRGSP ILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 785 RFFHEDVTLGNRSSPSGG-ASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTAN 843
F+HED+TLG+RS+PSGG AS NLSLT EHSGNYSCEA+NGLGAQRSE VTL T T
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
Query: 844 RSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVP 903
RS +GV GLLS G A ALL L RK GR+ A DP RS QE TY N P
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
Query: 904 AWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVAS 961
+LQP+Y N N + VYS Q +++ + H+ +K S IYS ++ A+
Sbjct: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAETLGTHMEDKVSLDIYSRLRKAN 418
Score = 211 bits (538), Expect = 2e-54
Identities = 122/280 (43%), Positives = 161/280 (57%), Gaps = 7/280 (2%)
Query: 194 LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSK 253
L AS P G+PVTLTC+ L+ SD +F FFRD + LG GWS SP QI AMW +
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPF-LQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 254 DSGFYWCKAATMPYSVISDSPRSWIQV-QIPASHPVLTLSPEKALNFEGTKVTLHCETQE 312
D+G YWC+A TM V+ S RS I V ++P + L P EG ++ L C
Sbjct: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 313 DSLRTLYRFYHEGVPLRHKSVRCERGASISF---SLTTENSGNYYCTADNGLGAKPSKAV 369
+ + +Y V L +S + +R + + S+ ++ YYC A+NG G PS V
Sbjct: 139 GTGDITFLWYKGAVGLNLQS-KTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
Query: 370 SLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSA 429
S++V +PVS P+L L +P + LHCEA RGS PILY F+HE L RSA S
Sbjct: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
Query: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVP 469
GG + + SLT EHSGNY C A+NG G QRS+AV+L+ TVP
Sbjct: 258 GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 203 bits (516), Expect = 7e-52
Identities = 124/270 (45%), Positives = 161/270 (59%), Gaps = 9/270 (3%)
Query: 393 EGAKVTLHCEA---QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCT 449
EG+ VTL C+ Q + F + AL +S+ + I+ ++ E +G+Y+C
Sbjct: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-GWSSSPKLQIA-AMWKEDTGSYWCE 87
Query: 450 ADNGFGPQ-RSKAVSLSV-TVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQF 507
A RS+ ++V VPV+ L EG + L C V G+ I + +
Sbjct: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
Query: 508 YHE--DMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSR 565
Y + L S + S+ S+ E + YYC A+NG+GP S +VS+ V +PVSR
Sbjct: 148 YKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
Query: 566 PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLT 625
PIL LR PRAQA V D+LELHCEA RGSPPILYWFYHED+TLGS SAPSGG ASFNLSLT
Sbjct: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
Query: 626 AEHSGNYSCEANNGLVAQHSDTISLSVIVP 655
EHSGNYSCEANNGL AQ S+ ++L+ VP
Sbjct: 268 EEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 198 bits (503), Expect = 2e-50
Identities = 130/296 (43%), Positives = 168/296 (56%), Gaps = 16/296 (5%)
Query: 464 LSVTVPVSHPV-LTLSSAEALTFEGATVTLHCEV---QRGSPQILYQFYHEDMPL---WS 516
L + P+ P L L ++ + EG+ VTL C++ Q Q + F+ + L WS
Sbjct: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
Query: 517 SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ-RSEVVSLFV-TVPVSRPILTLRVPR 574
SS ++ + ++ + +G+Y+C A RS + V VPV+ L + P
Sbjct: 67 SSP----KLQIA-AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
Query: 575 AQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGG-EASFNL-SLTAEHSGNY 632
Q + GD L L C G+ I + +Y V L S A + + S+ + Y
Sbjct: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Query: 633 SCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW 692
C A NG S +S++V +PVSRPIL RAPRAQA V D+LELHCEALRGS PILYW
Sbjct: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
Query: 693 FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVP 748
FYHED+TLG SAPSGGGASFNLSLT EHSG YSCEA+NGL AQRSE VTL VP
Sbjct: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 95.9 bits (237), Expect = 2e-19
Identities = 90/326 (27%), Positives = 140/326 (42%), Gaps = 35/326 (10%)
Query: 90 SPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA----KAEVTLNNTIYKNDNVLA-F 144
+PL P L ++ +P EG V L C+ ++ +++ L
Sbjct: 11 APLCEPAEL------FLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG 64
Query: 145 LNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPV---LRASSFQP 201
+ I +D G+Y C + + S +I V V + Q
Sbjct: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
Query: 202 ISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGW----SLSPNFQITAMWSKDSGF 257
+ G+ + L C S+ + F +++ L L SL+ ++I ++ D+
Sbjct: 125 MEGDRLVLIC----SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 258 YWCKAAT----MPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQED 313
Y+C A P ++S I V+IP S P+L L +A + LHCE
Sbjct: 181 YYCVAENGYGPSPSGLVS------ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRG 234
Query: 314 SLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSV 373
S LY FYHE + L +S GAS + SLT E+SGNY C A+NGLGA+ S+AV+L+
Sbjct: 235 SPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
Query: 374 TVPVSHPVLNLSSPEDLIFEGAKVTL 399
TVP +L+S + EG TL
Sbjct: 295 TVPTGARSNHLTSG---VIEGLLSTL 317
>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
Length = 429
Score = 240 bits (613), Expect = 4e-63
Identities = 170/420 (40%), Positives = 226/420 (53%), Gaps = 22/420 (5%)
Query: 557 LFVTVPVSRPI-LTLRVPRAQAVVGDLLELHCEAP---RGSPPILYWFYHEDVTLGSSSA 612
L + P+ P L L + G + L C+ P + F+ + LG
Sbjct: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP--- 63
Query: 613 PSGGEASFNLSLTA---EHSGNYSCEAN---NGLVAQHSDTISLSVIVPVSRPILTFRAP 666
G +S L + A E +G+Y CEA + ++ I++ VPV+ L + P
Sbjct: 64 --GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHR-VPVADVSLETQPP 120
Query: 667 RAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGG-GASFNL-SLTTEHSGI 724
Q + GD L L C G+ I + +Y V L S A + + S+ +
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 725 YSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILY 784
Y C A+NG S +V++ V +PVSRP+L LRAP AAV D+LELHCEALRGSP ILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 785 RFFHEDVTLGNRSSPSGG-ASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTAN 843
F+HED+TLG+RS+PSGG AS NLSLT EHSGNYSCEA+NGLGAQRSE VTL T T
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
Query: 844 RSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVP 903
RS +GV GLLS G A ALL L RK GR+ A DP RS QE TY N P
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
Query: 904 AWEELQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDP--RHLRNKGSPIIYSEVKVAS 961
+LQP+Y N N + VYS + + ++ +VA++ H+ +K S IYS ++ A+
Sbjct: 361 TPGQLQPIYENVNVVSGDEVYS-LAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKAN 419
Score = 211 bits (538), Expect = 2e-54
Identities = 122/280 (43%), Positives = 161/280 (57%), Gaps = 7/280 (2%)
Query: 194 LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSK 253
L AS P G+PVTLTC+ L+ SD +F FFRD + LG GWS SP QI AMW +
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPF-LQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 254 DSGFYWCKAATMPYSVISDSPRSWIQV-QIPASHPVLTLSPEKALNFEGTKVTLHCETQE 312
D+G YWC+A TM V+ S RS I V ++P + L P EG ++ L C
Sbjct: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 313 DSLRTLYRFYHEGVPLRHKSVRCERGASISF---SLTTENSGNYYCTADNGLGAKPSKAV 369
+ + +Y V L +S + +R + + S+ ++ YYC A+NG G PS V
Sbjct: 139 GTGDITFLWYKGAVGLNLQS-KTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
Query: 370 SLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSA 429
S++V +PVS P+L L +P + LHCEA RGS PILY F+HE L RSA S
Sbjct: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
Query: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVP 469
GG + + SLT EHSGNY C A+NG G QRS+AV+L+ TVP
Sbjct: 258 GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 203 bits (516), Expect = 7e-52
Identities = 124/270 (45%), Positives = 161/270 (59%), Gaps = 9/270 (3%)
Query: 393 EGAKVTLHCEA---QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCT 449
EG+ VTL C+ Q + F + AL +S+ + I+ ++ E +G+Y+C
Sbjct: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-GWSSSPKLQIA-AMWKEDTGSYWCE 87
Query: 450 ADNGFGPQ-RSKAVSLSV-TVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQF 507
A RS+ ++V VPV+ L EG + L C V G+ I + +
Sbjct: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
Query: 508 YHE--DMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSR 565
Y + L S + S+ S+ E + YYC A+NG+GP S +VS+ V +PVSR
Sbjct: 148 YKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
Query: 566 PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLT 625
PIL LR PRAQA V D+LELHCEA RGSPPILYWFYHED+TLGS SAPSGG ASFNLSLT
Sbjct: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
Query: 626 AEHSGNYSCEANNGLVAQHSDTISLSVIVP 655
EHSGNYSCEANNGL AQ S+ ++L+ VP
Sbjct: 268 EEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 198 bits (503), Expect = 2e-50
Identities = 130/296 (43%), Positives = 168/296 (56%), Gaps = 16/296 (5%)
Query: 464 LSVTVPVSHPV-LTLSSAEALTFEGATVTLHCEV---QRGSPQILYQFYHEDMPL---WS 516
L + P+ P L L ++ + EG+ VTL C++ Q Q + F+ + L WS
Sbjct: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
Query: 517 SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ-RSEVVSLFV-TVPVSRPILTLRVPR 574
SS ++ + ++ + +G+Y+C A RS + V VPV+ L + P
Sbjct: 67 SSP----KLQIA-AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
Query: 575 AQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGG-EASFNL-SLTAEHSGNY 632
Q + GD L L C G+ I + +Y V L S A + + S+ + Y
Sbjct: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Query: 633 SCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW 692
C A NG S +S++V +PVSRPIL RAPRAQA V D+LELHCEALRGS PILYW
Sbjct: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
Query: 693 FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVP 748
FYHED+TLG SAPSGGGASFNLSLT EHSG YSCEA+NGL AQRSE VTL VP
Sbjct: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 95.9 bits (237), Expect = 2e-19
Identities = 90/326 (27%), Positives = 140/326 (42%), Gaps = 35/326 (10%)
Query: 90 SPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA----KAEVTLNNTIYKNDNVLA-F 144
+PL P L ++ +P EG V L C+ ++ +++ L
Sbjct: 11 APLCEPAEL------FLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG 64
Query: 145 LNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPV---LRASSFQP 201
+ I +D G+Y C + + S +I V V + Q
Sbjct: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
Query: 202 ISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGW----SLSPNFQITAMWSKDSGF 257
+ G+ + L C S+ + F +++ L L SL+ ++I ++ D+
Sbjct: 125 MEGDRLVLIC----SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 258 YWCKAAT----MPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQED 313
Y+C A P ++S I V+IP S P+L L +A + LHCE
Sbjct: 181 YYCVAENGYGPSPSGLVS------ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRG 234
Query: 314 SLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSV 373
S LY FYHE + L +S GAS + SLT E+SGNY C A+NGLGA+ S+AV+L+
Sbjct: 235 SPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
Query: 374 TVPVSHPVLNLSSPEDLIFEGAKVTL 399
TVP +L+S + EG TL
Sbjct: 295 TVPTGARSNHLTSG---VIEGLLSTL 317
>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
Length = 366
Score = 207 bits (527), Expect = 4e-53
Identities = 120/278 (43%), Positives = 159/278 (57%), Gaps = 7/278 (2%)
Query: 194 LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSK 253
L AS P G+PVTLTC+ L+ SD +F FFRD + LG GWS SP QI AMW +
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPF-LQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 254 DSGFYWCKAATMPYSVISDSPRSWIQV-QIPASHPVLTLSPEKALNFEGTKVTLHCETQE 312
D+G YWC+A TM V+ S RS I V ++P + L P EG ++ L C
Sbjct: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 313 DSLRTLYRFYHEGVPLRHKSVRCERGASISF---SLTTENSGNYYCTADNGLGAKPSKAV 369
+ + +Y V L +S + +R + + S+ ++ YYC A+NG G PS V
Sbjct: 139 GTGDITFLWYKGAVGLNLQS-KTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
Query: 370 SLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSA 429
S++V +PVS P+L L +P + LHCEA RGS PILY F+HE L RSA S
Sbjct: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
Query: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVT 467
GG + + SLT EHSGNY C A+NG G QRS+AV+L+ T
Sbjct: 258 GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT 295
Score = 199 bits (507), Expect = 8e-51
Identities = 122/266 (45%), Positives = 159/266 (59%), Gaps = 9/266 (3%)
Query: 393 EGAKVTLHCEA---QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCT 449
EG+ VTL C+ Q + F + AL +S+ + I+ ++ E +G+Y+C
Sbjct: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-GWSSSPKLQIA-AMWKEDTGSYWCE 87
Query: 450 ADNGFGPQ-RSKAVSLSV-TVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQF 507
A RS+ ++V VPV+ L EG + L C V G+ I + +
Sbjct: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
Query: 508 YHE--DMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSR 565
Y + L S + S+ S+ E + YYC A+NG+GP S +VS+ V +PVSR
Sbjct: 148 YKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
Query: 566 PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLT 625
PIL LR PRAQA V D+LELHCEA RGSPPILYWFYHED+TLGS SAPSGG ASFNLSLT
Sbjct: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
Query: 626 AEHSGNYSCEANNGLVAQHSDTISLS 651
EHSGNYSCEANNGL AQ S+ ++L+
Sbjct: 268 EEHSGNYSCEANNGLGAQRSEAVTLN 293
Score = 194 bits (493), Expect = 3e-49
Identities = 128/291 (43%), Positives = 166/291 (57%), Gaps = 16/291 (5%)
Query: 464 LSVTVPVSHPV-LTLSSAEALTFEGATVTLHCEV---QRGSPQILYQFYHEDMPL---WS 516
L + P+ P L L ++ + EG+ VTL C++ Q Q + F+ + L WS
Sbjct: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
Query: 517 SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ-RSEVVSLFV-TVPVSRPILTLRVPR 574
SS ++ + ++ + +G+Y+C A RS + V VPV+ L + P
Sbjct: 67 SSP----KLQIA-AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
Query: 575 AQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGG-EASFNL-SLTAEHSGNY 632
Q + GD L L C G+ I + +Y V L S A + + S+ + Y
Sbjct: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Query: 633 SCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW 692
C A NG S +S++V +PVSRPIL RAPRAQA V D+LELHCEALRGS PILYW
Sbjct: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
Query: 693 FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTL 743
FYHED+TLG SAPSGGGASFNLSLT EHSG YSCEA+NGL AQRSE VTL
Sbjct: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
Score = 191 bits (486), Expect = 2e-48
Identities = 143/379 (37%), Positives = 187/379 (49%), Gaps = 59/379 (15%)
Query: 557 LFVTVPVSRPI-LTLRVPRAQAVVGDLLELHCEAP---RGSPPILYWFYHEDVTLGSSSA 612
L + P+ P L L + G + L C+ P + F+ + LG
Sbjct: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP--- 63
Query: 613 PSGGEASFNLSLTA---EHSGNYSCEAN---NGLVAQHSDTISLSVIVPVSRPILTFRAP 666
G +S L + A E +G+Y CEA + ++ I++ VPV+ L + P
Sbjct: 64 --GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHR-VPVADVSLETQPP 120
Query: 667 RAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGG-GASFNL-SLTTEHSGI 724
Q + GD L L C G+ I + +Y V L S A + + S+ +
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 725 YSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILY 784
Y C A+NG S +V++ V +PVSRP+L LRAP AAV D+LELHCEALRGSP ILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 785 RFFHEDVTLGNRSSPS-GGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTAN 843
F+HED+TLG+RS+PS GGAS NLSLT EHSGNYSCEA+NGLGAQRSE VTL T
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT----- 295
Query: 844 RSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVP 903
GR+ A DP RS QE TY N P
Sbjct: 296 ----------------------------------GRRSARDPLRSLPSPLPQEFTYLNSP 321
Query: 904 AWEELQPVYTNANPRGENV 922
+LQP+Y N PR ++V
Sbjct: 322 TPGQLQPIYEN-EPREQSV 339
Score = 148 bits (373), Expect = 3e-35
Identities = 105/306 (34%), Positives = 149/306 (48%), Gaps = 32/306 (10%)
Query: 274 PRSWIQVQIPASHPV-LTLSPEKALNFEGTKVTLHCET---QEDSLRTLYRFYHEGVPLR 329
PR + + P P L L + EG+ VTL C+ Q + + F+ + L
Sbjct: 3 PRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALG 62
Query: 330 ---HKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTV---PVSHPVLN 383
S + + A + E++G+Y+C A + +K ++ + V PV+ L
Sbjct: 63 PGWSSSPKLQIAA-----MWKEDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLE 116
Query: 384 LSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEH- 442
P + EG ++ L C G+ I + ++ L +S SLTAE+
Sbjct: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQR-------SLTAEYE 169
Query: 443 --------SGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHC 494
+ YYC A+NG+GP S VS++V +PVS P+L L + A + LHC
Sbjct: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
Query: 495 EVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEV 554
E RGSP ILY FYHED+ L S S PS G SF+ SLTE HSGNY C A+NG G QRSE
Sbjct: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
Query: 555 VSLFVT 560
V+L T
Sbjct: 290 VTLNFT 295
>gi|50878302 Fc receptor-like B [Homo sapiens]
Length = 426
Score = 166 bits (419), Expect = 1e-40
Identities = 108/301 (35%), Positives = 158/301 (52%), Gaps = 21/301 (6%)
Query: 7 LLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFR----FYSPQKTKWYHRYL 62
LL+L P SGQ A +PI+ L PPWTT+F+GERVTL C G+ P T W YL
Sbjct: 7 LLLLVPSSGQAATLEKPILSLHPPWTTIFKGERVTLKCDGYHPLLLELQPISTLW---YL 63
Query: 63 GKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLS-VFEGDSVVL 121
G +L + +EVQ G YRCQ +G+P+S P+HL S+ LILQ P + VFEG+ +VL
Sbjct: 64 G-HLLLPSHKKSIEVQTPGVYRCQTRGAPVSDPIHLSVSNDWLILQVPYAPVFEGEPLVL 122
Query: 122 RCRAKAEVTLNNTIYKND-NVLAFLNKRTDFHIPHACLKDNGAYRCTGYKE---SCCPVS 177
RCR + + Y +D + + + ++ + A D+G Y+C+G P+
Sbjct: 123 RCRGWYDKVVYKLHYYHDGQAVRYFHSSANYTVLQARASDSGRYQCSGTMRIPVESAPMF 182
Query: 178 SNTVKIQVQEPFTRPVLRASSFQPISG---NPVTLTCETQLSLERSDVPLRFRFFRDDQT 234
S V + VQE F PVLR + G V L C+T+L ++ D PL+F F++ +
Sbjct: 183 SAKVAVTVQELFRAPVLRVMGPREARGAALGGVVLRCDTRLHPQKRDTPLQFAFYKYSRA 242
Query: 235 LGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPAS--HPVLTLS 292
+ + + + ++ YWC+AAT SV SP W+Q+ P S P T +
Sbjct: 243 V-RRFDWGAEYTVPEPEVEELESYWCEAATATRSVRKRSP--WLQLPGPGSPLDPASTTA 299
Query: 293 P 293
P
Sbjct: 300 P 300
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/237 (24%), Positives = 90/237 (37%), Gaps = 37/237 (15%)
Query: 287 PVLTLSPEKALNFEGTKVTLHCE------TQEDSLRTLYRFYHEGVPLRHKSVRCERGAS 340
P+L+L P F+G +VTL C+ + + TL+ H +P KS+
Sbjct: 23 PILSLHPPWTTIFKGERVTLKCDGYHPLLLELQPISTLWYLGHLLLPSHKKSIE------ 76
Query: 341 ISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLH 400
+ G Y C GA S + LSV S+ L L P +FEG + L
Sbjct: 77 ------VQTPGVYRCQTR---GAPVSDPIHLSV----SNDWLILQVPYAPVFEGEPLVLR 123
Query: 401 CEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSK 460
C + ++H+G A+ R +S+ + A SG Y C+ + +
Sbjct: 124 CRGWYDKVVYKLHYYHDGQAV--RYFHSSANYTV-LQARASDSGRYQCSGTMRIPVESAP 180
Query: 461 AVSLSVTVPVSH----PVL-TLSSAEALTFEGATVTLHCEV----QRGSPQILYQFY 508
S V V V PVL + EA V L C+ Q+ + + FY
Sbjct: 181 MFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVVLRCDTRLHPQKRDTPLQFAFY 237
Score = 43.1 bits (100), Expect = 0.001
Identities = 77/320 (24%), Positives = 115/320 (35%), Gaps = 56/320 (17%)
Query: 563 VSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILY--------WFYHEDVTLGSSSAPS 614
+ +PIL+L P G+ + L C+ G P+L W+ LG PS
Sbjct: 20 LEKPILSLHPPWTTIFKGERVTLKCD---GYHPLLLELQPISTLWY------LGHLLLPS 70
Query: 615 GGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGD 674
+ S+ + G Y C+ V SD I LSV S L + P A G+
Sbjct: 71 HKK-----SIEVQTPGVYRCQTRGAPV---SDPIHLSV----SNDWLILQVPYAPVFEGE 118
Query: 675 LLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFN-LSLTTEHSGIYSCEADNGL 733
L L C +YH+ G+ A++ L SG Y C +
Sbjct: 119 PLVLRCRGWYDKVVYKLHYYHD----GQAVRYFHSSANYTVLQARASDSGRYQCSGTMRI 174
Query: 734 EAQRSEMVTLKVAVPVSR----PVLTLRAP--GTHAAVGDLLELHCEA-----LRGSPLI 782
+ + M + KVAV V PVL + P AA+G ++ L C+ R +PL
Sbjct: 175 PVESAPMFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVV-LRCDTRLHPQKRDTPL- 232
Query: 783 LYRFFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITG--- 839
+F + R G E +Y CEA + R + L + G
Sbjct: 233 --QFAFYKYSRAVRRFDWGAEYTVPEPEVEELESYWCEAATATRSVRKRSPWLQLPGPGS 290
Query: 840 ----LTANRSGPFATGVAGG 855
+ P+A +A G
Sbjct: 291 PLDPASTTAPAPWAAALAPG 310
Score = 40.8 bits (94), Expect = 0.006
Identities = 55/235 (23%), Positives = 88/235 (37%), Gaps = 41/235 (17%)
Query: 204 GNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAA 263
G VTL C+ L P+ ++ LG L P+ + ++ + G Y C+
Sbjct: 37 GERVTLKCDGYHPLLLELQPISTLWY-------LGHLLLPSHK-KSIEVQTPGVYRCQTR 88
Query: 264 TMPYS--VISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRF 321
P S + W+ +Q+P + PV FEG + L C D + +
Sbjct: 89 GAPVSDPIHLSVSNDWLILQVPYA-PV----------FEGEPLVLRCRGWYDKVVYKLHY 137
Query: 322 YHEGVPLR--HKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSH 379
YH+G +R H S +SG Y C+ + + + S V V V
Sbjct: 138 YHDGQAVRYFHSSAN-----YTVLQARASDSGRYQCSGTMRIPVESAPMFSAKVAVTVQE 192
Query: 380 ----PVLNLSSPEDLIFEGAK---VTLHCEA----QRGSLPILYQFHHEGAALER 423
PVL + P + GA V L C+ Q+ P+ + F+ A+ R
Sbjct: 193 LFRAPVLRVMGPREA--RGAALGGVVLRCDTRLHPQKRDTPLQFAFYKYSRAVRR 245
Score = 37.7 bits (86), Expect = 0.053
Identities = 58/241 (24%), Positives = 91/241 (37%), Gaps = 45/241 (18%)
Query: 380 PVLNLSSPEDLIFEGAKVTLHCEAQRGSL----PI--LYQFHHEGAALERRSANSAGGVA 433
P+L+L P IF+G +VTL C+ L PI L+ H ++
Sbjct: 23 PILSLHPPWTTIFKGERVTLKCDGYHPLLLELQPISTLWYLGHLLLPSHKK--------- 73
Query: 434 ISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLH 493
S+ + G Y C R VS + + VS+ L L A FEG + L
Sbjct: 74 ---SIEVQTPGVYRCQT-------RGAPVSDPIHLSVSNDWLILQVPYAPVFEGEPLVLR 123
Query: 494 CEVQRGSPQILYQFYHEDMPL---WSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ 550
C +YH+ + SS+ +V + S SG Y C+ +
Sbjct: 124 CRGWYDKVVYKLHYYHDGQAVRYFHSSANYTVLQARAS------DSGRYQCSGTMRIPVE 177
Query: 551 RSEVVSLFVTVPVSR----PILTLRVPRAQ--AVVGDLLELHCEA----PRGSPPILYWF 600
+ + S V V V P+L + PR A +G ++ L C+ + P+ + F
Sbjct: 178 SAPMFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVV-LRCDTRLHPQKRDTPLQFAF 236
Query: 601 Y 601
Y
Sbjct: 237 Y 237
>gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64)
[Homo sapiens]
Length = 374
Score = 157 bits (397), Expect = 5e-38
Identities = 105/286 (36%), Positives = 147/286 (51%), Gaps = 14/286 (4%)
Query: 3 LWVI--LLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
+W + LL+ PV GQ T + +I LQPPW +VFQ E VTL C+ T+W+
Sbjct: 1 MWFLTTLLLWVPVDGQ-VDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLN 59
Query: 61 YLGKEILRETPD---NILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVF-EG 116
G TP V +SGEYRCQ S S P+ L+ L+LQ VF EG
Sbjct: 60 --GTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEG 117
Query: 117 DSVVLRCRA-KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCP 175
+ + LRC A K ++ N Y+N F + ++ I + NG Y C+G +
Sbjct: 118 EPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKH--R 175
Query: 176 VSSNTVKIQVQEPFTRPVLRASSFQP-ISGNPVTLTCETQLSLERSDVPLRFRFFRDDQT 234
+S + + V+E F PVL AS P + GN VTL+CET+L L+R + L F F+ +T
Sbjct: 176 YTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKT 235
Query: 235 LGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQV 280
L G + S +QI +DSG YWC+AAT +V+ SP +QV
Sbjct: 236 L-RGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQV 280
Score = 64.7 bits (156), Expect = 4e-10
Identities = 69/274 (25%), Positives = 109/274 (39%), Gaps = 28/274 (10%)
Query: 277 WIQV--QIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVR 334
W+ V Q+ + V+TL P F+ VTLHCE + +++ G + +
Sbjct: 10 WVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNGT-----ATQ 64
Query: 335 CERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEG 394
+ S + +SG Y C GL + S + + + L L + EG
Sbjct: 65 TSTPSYRITSASVNDSGEYRC--QRGLSGR-----SDPIQLEIHRGWLLLQVSSRVFTEG 117
Query: 395 AKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGF 454
+ L C A + L ++ G A + NS + H+G Y+C +G
Sbjct: 118 EPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTI---LKTNISHNGTYHC---SGM 171
Query: 455 GPQRSKAVSLSVTVPVSHPVLTL-SSAEALTFEGATVTLHCE----VQRGSPQILYQFYH 509
G R + +SVTV P L +S + EG VTL CE +QR Q+ + FY
Sbjct: 172 GKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYM 231
Query: 510 EDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTA 543
L +T S ++ + SG Y+C A
Sbjct: 232 GSKTLRGRNTSSEYQI---LTARREDSGLYWCEA 262
Score = 46.2 bits (108), Expect = 1e-04
Identities = 85/326 (26%), Positives = 124/326 (38%), Gaps = 57/326 (17%)
Query: 468 VPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSF 527
V + V+TL F+ TVTLHCEV Q++ +STPS S
Sbjct: 17 VDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNGTAT-QTSTPSYRITSA 75
Query: 528 SFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHC 587
S + SG Y C G RS+ + L + R L L+V G+ L L C
Sbjct: 76 SVN----DSGEYRC--QRGLS-GRSDPIQL----EIHRGWLLLQVSSRVFTEGEPLALRC 124
Query: 588 EAPRGS--PPILYW-------FYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANN 638
A + +LY+ F+H + L L H+G Y C +
Sbjct: 125 HAWKDKLVYNVLYYRNGKAFKFFHWNSNLTI------------LKTNISHNGTYHC---S 169
Query: 639 GLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVV-GDLLELHCEA----LRGSSPILYWF 693
G+ + +SV V P A ++ G+L+ L CE R + + F
Sbjct: 170 GMGKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSF 229
Query: 694 YHEDVTLGKISAPSGGGASFNLSLTT---EHSGIYSCEA--DNGLEAQRS-----EMVTL 743
Y TL G S + T E SG+Y CEA ++G +RS +++ L
Sbjct: 230 YMGSKTL------RGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGL 283
Query: 744 KVAVPVSRPVLTLRAPGTHAAVGDLL 769
++ PV VL A G V +L
Sbjct: 284 QLPTPVWFHVLFYLAVGIMFLVNTVL 309
>gi|157057547 Fc receptor-like 6 [Homo sapiens]
Length = 434
Score = 133 bits (335), Expect = 7e-31
Identities = 129/408 (31%), Positives = 187/408 (45%), Gaps = 45/408 (11%)
Query: 580 GDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNG 639
GD L L C+ + +P FY + L S + + T + G YSC
Sbjct: 32 GDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKE---NQTLSMGAATVQSRGQYSCSGQVM 88
Query: 640 LVAQHSDTISLSVIVPVSR----PILTFRAPRAQAVVGDLLELHCEA----LRGSSPILY 691
+ Q S + +V V P+L+ P + G L+ L C+ LR + +L+
Sbjct: 89 YIPQTFTQTSETAMVQVQELFPPPVLS-AIPSPEPREGSLVTLRCQTKLHPLRSALRLLF 147
Query: 692 WFYHEDVTLGKISAPSGGGASFNLSLTTE-HSGIYSCEA--DNGLEAQRSEMVTLKVAVP 748
F+ + TL G + E SG+Y CE + G ++S + ++V P
Sbjct: 148 SFHKDGHTL----QDRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLEVRVQAP 203
Query: 749 VSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPSGG-ASLNL 807
VSRPVLTL AVGD+++L CEA RGSP ILY F+ ++ +GN S+P GG SL
Sbjct: 204 VSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAPCGGTTSLLF 263
Query: 808 SLTAEH-SGNYSCEADNGLGAQRSETVTLYITG---LTANRSGPFATGVAGGLLSIAGLA 863
+ +E +GNYSCEA+N + +RSE L + G L S + LL + +A
Sbjct: 264 PVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVPWLPASLLGLMVIA 323
Query: 864 AGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVPAWEELQPVYTNANPRGENVV 923
A ALL+Y RKAG P+ P +P Q P Y NV + + E VV
Sbjct: 324 A-ALLVYVRSWRKAGPLPSQIPPTAP--GGEQCPLYANV----------HHQKGKDEGVV 370
Query: 924 YSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVK------VASTPVS 965
YS V + K+ S + K S II +EV+ V+ST V+
Sbjct: 371 YSVVH--RTSKRSEARSAEFTVGRKDSSIICAEVRCLQPSEVSSTEVN 416
Score = 131 bits (330), Expect = 3e-30
Identities = 98/276 (35%), Positives = 134/276 (48%), Gaps = 8/276 (2%)
Query: 105 LILQA-PLSVFEGDSVVLRCRAKAEVTLNNT-IYKNDNVLAFLNKRTDFHIPHACLKDNG 162
L LQA P VFEGD++ LRC+ L+ Y++ L F + + A ++ G
Sbjct: 20 LYLQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMGAATVQSRG 79
Query: 163 AYRCTG---YKESCCPVSSNTVKIQVQEPFTRPVLRA-SSFQPISGNPVTLTCETQLSLE 218
Y C+G Y +S T +QVQE F PVL A S +P G+ VTL C+T+L
Sbjct: 80 QYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTKLHPL 139
Query: 219 RSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWI 278
RS + L F F +D TL P I DSG YWC+ A V SP+ +
Sbjct: 140 RSALRLLFSFHKDGHTLQ-DRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLEV 198
Query: 279 QVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERG 338
+VQ P S PVLTL A G V L CE Q S LY FY + + + S C
Sbjct: 199 RVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAPCGGT 258
Query: 339 ASISFSLTTE-NSGNYYCTADNGLGAKPSKAVSLSV 373
S+ F + +E ++GNY C A+N + + S+ LS+
Sbjct: 259 TSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSL 294
Score = 120 bits (301), Expect = 6e-27
Identities = 88/274 (32%), Positives = 135/274 (49%), Gaps = 20/274 (7%)
Query: 391 IFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTA 450
+FEG +TL C+ + + +F+ +G L N + + T + G Y C+
Sbjct: 29 VFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMGAA---TVQSRGQYSCSG 85
Query: 451 DNGFGPQRSKAVSLSVTVPVSH----PVLT-LSSAEALTFEGATVTLHCEVQ----RGSP 501
+ PQ S + V V PVL+ + S E EG+ VTL C+ + R +
Sbjct: 86 QVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPR--EGSLVTLRCQTKLHPLRSAL 143
Query: 502 QILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTA--DNGFGPQRSEVVSLFV 559
++L+ F+ + L + EG SG Y+C + G ++S + + V
Sbjct: 144 RLLFSFHKDGHTLQDRGPHPELCIP---GAKEGDSGLYWCEVAPEGGQVQKQSPQLEVRV 200
Query: 560 TVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEAS 619
PVSRP+LTL A VGD+++L CEA RGSPPILY FY ++ +G+ SAP GG S
Sbjct: 201 QAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAPCGGTTS 260
Query: 620 FNLSLTAEH-SGNYSCEANNGLVAQHSDTISLSV 652
+ +E +GNYSCEA N + + S+ LS+
Sbjct: 261 LLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSL 294
Score = 97.1 bits (240), Expect = 7e-20
Identities = 86/280 (30%), Positives = 125/280 (44%), Gaps = 34/280 (12%)
Query: 204 GNPVTLTCETQLSLERSDVPLR-----FRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFY 258
G+ +TL C+ + S V F +++QTL +G A + G Y
Sbjct: 32 GDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMG----------AATVQSRGQY 81
Query: 259 WCKAATM--PYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQ----E 312
C M P + S + +QVQ PVL+ P EG+ VTL C+T+
Sbjct: 82 SCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPR-EGSLVTLRCQTKLHPLR 140
Query: 313 DSLRTLYRFYHEGVPLRHKSVR---CERGASISFSLTTENSGNYYCTA--DNGLGAKPSK 367
+LR L+ F+ +G L+ + C GA +SG Y+C + G K S
Sbjct: 141 SALRLLFSFHKDGHTLQDRGPHPELCIPGAKEG------DSGLYWCEVAPEGGQVQKQSP 194
Query: 368 AVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSAN 427
+ + V PVS PVL L G V L CEAQRGS PILY F+ + + SA
Sbjct: 195 QLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAP 254
Query: 428 SAGGVAISFSLTAEH-SGNYYCTADNGFGPQRSKAVSLSV 466
G ++ F + +E +GNY C A+N +RS+ LS+
Sbjct: 255 CGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSL 294
Score = 70.1 bits (170), Expect = 1e-11
Identities = 78/293 (26%), Positives = 126/293 (43%), Gaps = 46/293 (15%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW +L+ P G+ ++LQ VF+G+ +TL C+G++ + K+Y
Sbjct: 1 MLLWTAVLLFVPCVGKTVW-----LYLQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRD 55
Query: 61 YLGKEILRETPDNILE-----VQESGEYRCQAQGSPLSSPVHLDFSSASLILQA----PL 111
GK + + L VQ G+Y C G + P +S + ++Q P
Sbjct: 56 --GKFLHFSKENQTLSMGAATVQSRGQYSC--SGQVMYIPQTFTQTSETAMVQVQELFPP 111
Query: 112 SVF---------EGDSVVLRCRAK-----AEVTLNNTIYKNDNVLAFLNKRTDFHIPHAC 157
V EG V LRC+ K + + L + +K+ + L + IP A
Sbjct: 112 PVLSAIPSPEPREGSLVTLRCQTKLHPLRSALRLLFSFHKDGHTLQDRGPHPELCIPGAK 171
Query: 158 LKDNGAYRCTGYKE-SCCPVSSNTVKIQVQEPFTRPV--LRASSFQPISGNPVTLTCETQ 214
D+G Y C E S ++++VQ P +RPV L P G+ V L CE Q
Sbjct: 172 EGDSGLYWCEVAPEGGQVQKQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQ 231
Query: 215 LSLERSDVPLRFRFFRDDQTLG-----LGWSLSPNFQITAMWSKDSGFYWCKA 262
R P+ + F+ D++ +G G + S F + + +D+G Y C+A
Sbjct: 232 ----RGSPPILYSFYLDEKIVGNHSAPCGGTTSLLFPVKS--EQDAGNYSCEA 278
>gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens]
Length = 376
Score = 124 bits (310), Expect = 6e-28
Identities = 88/236 (37%), Positives = 127/236 (53%), Gaps = 13/236 (5%)
Query: 70 TPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLS-VFEGDSVVLRCRAKAE 128
T D++ + +E+G Q + S P HL S LILQ P VFEGD +VLRC+A +
Sbjct: 65 TEDDLTDAREAG---FQVKAYTFSEPFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQD 121
Query: 129 VTLNN-TIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESC---CPVSSNTVKIQ 184
L T Y++ + L +F I D+G Y C+G +S P +++ V I
Sbjct: 122 WPLTQVTFYRDGSALGPPGPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAIT 181
Query: 185 VQEPFTRPVLRA-SSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSP 243
VQE F P+LRA S +P +G+P+TL+C+T+L L+RS L F F++D + + LS
Sbjct: 182 VQELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIV-QSRGLSS 240
Query: 244 NFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQ---IPASHPVLTLSPEKA 296
FQI SG YWC+AAT V SP+ I+VQ A+ P L +P+K+
Sbjct: 241 EFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKS 296
Score = 57.8 bits (138), Expect = 5e-08
Identities = 63/232 (27%), Positives = 103/232 (44%), Gaps = 24/232 (10%)
Query: 377 VSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISF 436
VS+ L L P +FEG + L C+A + F+ +G+AL N + +
Sbjct: 92 VSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALGPPGPNREFSITV-- 149
Query: 437 SLTAEHSGNYYCTA---DNGFG-PQRSKAVSLSVTVPVSHPVL-TLSSAEALTFEGATVT 491
+ SG+Y+C+ G G P+ + V+++V P+L + SAE G+ +T
Sbjct: 150 -VQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQA--GSPMT 206
Query: 492 LHCE----VQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYC---TAD 544
L C+ +QR + ++L+ FY + + S S ++ + +E HSG+Y+C T D
Sbjct: 207 LSCQTKLPLQRSAARLLFSFYKDGRIVQSRGLSSEFQIP---TASEDHSGSYWCEAATED 263
Query: 545 NGFGPQRSEVVSLFVTVPVSRPILTLR-VPRAQAVVGDLLELHCEAPRGSPP 595
N Q ++ S TL P+ A G E EAP PP
Sbjct: 264 NQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKSAAPGTAPE---EAPGPLPP 312
Score = 56.6 bits (135), Expect = 1e-07
Identities = 59/218 (27%), Positives = 98/218 (44%), Gaps = 23/218 (10%)
Query: 563 VSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNL 622
VS L L+ P GDLL L C+A + P FY + GS+ P G F++
Sbjct: 92 VSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRD----GSALGPPGPNREFSI 147
Query: 623 SLTAE-HSGNYSC----EANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLE 677
++ + SG+Y C ++ + + + ++++V PIL P A+ G +
Sbjct: 148 TVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILR-AVPSAEPQAGSPMT 206
Query: 678 LHCEA----LRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTE-HSGIYSCEA--- 729
L C+ R ++ +L+ FY + G+I G + F + +E HSG Y CEA
Sbjct: 207 LSCQTKLPLQRSAARLLFSFYKD----GRIVQSRGLSSEFQIPTASEDHSGSYWCEAATE 262
Query: 730 DNGLEAQRSEM-VTLKVAVPVSRPVLTLRAPGTHAAVG 766
DN + Q ++ + ++ A + P AP AA G
Sbjct: 263 DNQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKSAAPG 300
Score = 54.7 bits (130), Expect = 4e-07
Identities = 63/232 (27%), Positives = 99/232 (42%), Gaps = 41/232 (17%)
Query: 277 WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCE 336
W+ +Q PA PV FEG + L C+ +D T FY +G S
Sbjct: 96 WLILQGPAK-PV----------FEGDLLVLRCQAWQDWPLTQVTFYRDG------SALGP 138
Query: 337 RGASISFSLTT---ENSGNYYCTA---DNGLGAKPSKAVSLSVTVPVSHPVLNLSS-PED 389
G + FS+T +SG+Y+C+ G G P A +++TV P L + P
Sbjct: 139 PGPNREFSITVVQKADSGHYHCSGIFQSPGPGI-PETASVVAITVQELFPAPILRAVPSA 197
Query: 390 LIFEGAKVTLHCEA----QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGN 445
G+ +TL C+ QR + +L+ F+ +G ++ R +S + + + +HSG+
Sbjct: 198 EPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQSRGLSSEFQIP---TASEDHSGS 254
Query: 446 YYC---TADNGFGPQ------RSKAVSLSVTVPVSHPVLTLSSAEALTFEGA 488
Y+C T DN Q R + S S P +P S+A E A
Sbjct: 255 YWCEAATEDNQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKSAAPGTAPEEA 306
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/206 (25%), Positives = 82/206 (39%), Gaps = 24/206 (11%)
Query: 656 VSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNL 715
VS L + P GDLL L C+A + FY + LG P G F++
Sbjct: 92 VSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALG----PPGPNREFSI 147
Query: 716 SLTTE-HSGIYSCEADNGLEAQRSEMVTLKVAVPVSR--PVLTLRA-PGTHAAVGDLLEL 771
++ + SG Y C VA+ V P LRA P G + L
Sbjct: 148 TVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQAGSPMTL 207
Query: 772 HCEAL----RGSPLILYRFFHEDVTLGNRSSPSGGASLNLSL---TAEHSGNYSCEA--- 821
C+ R + +L+ F+ + R S G S + + +HSG+Y CEA
Sbjct: 208 SCQTKLPLQRSAARLLFSFYKD-----GRIVQSRGLSSEFQIPTASEDHSGSYWCEAATE 262
Query: 822 DNGLGAQRSETVTLYITGLTANRSGP 847
DN + Q S + + + G +++ + P
Sbjct: 263 DNQVWKQ-SPQLEIRVQGASSSAAPP 287
Score = 36.2 bits (82), Expect = 0.15
Identities = 36/166 (21%), Positives = 67/166 (40%), Gaps = 19/166 (11%)
Query: 25 IFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYH--RYLGKE-ILRETPDNILEVQESG 81
+ LQ P VF+G+ + L C+ ++ + + +Y LG RE +++ +SG
Sbjct: 97 LILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALGPPGPNREFSITVVQKADSG 156
Query: 82 EYRC----QAQGSPLSSPVHLDFSSASLILQAPL-------SVFEGDSVVLRCRAK---- 126
Y C Q+ G + + + + AP+ G + L C+ K
Sbjct: 157 HYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQ 216
Query: 127 -AEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKE 171
+ L + YK+ ++ ++F IP A +G+Y C E
Sbjct: 217 RSAARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHSGSYWCEAATE 262
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 113 bits (282), Expect = 1e-24
Identities = 192/811 (23%), Positives = 304/811 (37%), Gaps = 100/811 (12%)
Query: 76 EVQESGEYRCQAQ--GSPLSSPVHLDFSSASLILQ--APLSVFEGDSVVLRCRAKAEVTL 131
E +G+Y CQ + G + L ++I++ P++V G++ L C+ L
Sbjct: 5674 EPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPEL 5733
Query: 132 NNTIYKNDNVL--------AFLNKRTDFHIPHACLKDNGAYRC---TGYKESCCPVSSNT 180
+ YK+ +L +F NK + I +D G Y +S C +
Sbjct: 5734 SVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDV 5793
Query: 181 VKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWS 240
V FTR R + + G L C+ S P+ +F + + G
Sbjct: 5794 SDRAVPPSFTR---RLKNTGGVLGASCILECKVAGSS-----PISVAWFHEKTKIVSGAK 5845
Query: 241 LSPNF-------QITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSP 293
F Q+ ++ S D G Y C AA + S D R+ + VQ P P P
Sbjct: 5846 YQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGS---DECRAVLTVQEP---PSFVKEP 5899
Query: 294 EKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRC-----ERGASIS-FSLTT 347
E G VT + + F G K RC + A + F++
Sbjct: 5900 EPLEVLPGKNVTFTSVIRGTPPFKVNWF--RGARELVKGDRCNIYFEDTVAELELFNIDI 5957
Query: 348 ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGS 407
SG Y C N G S + + V P L D E K + G+
Sbjct: 5958 SQSGEYTCVVSNNAGQ-----ASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGT 6012
Query: 408 LPILYQFHHEGAAL---ERRSANSAGGVAISFSL--TAEHSGNYYCTADNGFGPQRSKAV 462
LPI + +G + E+ + + I L T +G Y C +N G R
Sbjct: 6013 LPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAG--RDVCG 6070
Query: 463 SLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSS---- 518
+L T+ + V L EA G +V+L C+V G+P+I +Y D L +
Sbjct: 6071 ALVSTLEPPYFVTELEPLEAAV--GDSVSLQCQVA-GTPEITVSWYKGDTKLRPTPEYRT 6127
Query: 519 --TPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQ 576
T +V + F+ + SG Y C A+N G S+ V + P ++ +
Sbjct: 6128 YFTNNVATLVFN-KVNINDSGEYTCKAENSIGTASSKTVFRIQERQLP-PSFARQLKDIE 6185
Query: 577 AVVGDLLELHCEAPRGSPPILYWFYHEDVTLGS-----SSAPSGGEASFNLSLTAEHSGN 631
VG + L C GS PI +Y + V L +S L HSG
Sbjct: 6186 QTVGLPVTLTCRL-NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQ 6244
Query: 632 YSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILY 691
YSC A+N L S + L+ P P + + G+ + C + G+ P+
Sbjct: 6245 YSCSASNPL-GTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECH-VTGAQPMRI 6302
Query: 692 WFYHEDVTLGKISAPSGGGASFNLSLTTEH----------SGIYSCEADNGLEAQRSEMV 741
+ ++ + GG + T H SG Y+C+A N + +M
Sbjct: 6303 TWSKDNKEIRP-----GGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG---KDMC 6354
Query: 742 TLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLG-----NR 796
+ +++V + A G+ ++L C+ + GSP I +F D L N
Sbjct: 6355 SAQLSVKEPPKFVKKLEASKVAKQGESIQLECK-ISGSPEIKVSWFRNDSELHESWKYNM 6413
Query: 797 SSPSGGASLNLS-LTAEHSGNYSCEADNGLG 826
S + A L ++ +AE SG+Y CEA NG+G
Sbjct: 6414 SFINSVALLTINEASAEDSGDYICEAHNGVG 6444
Score = 112 bits (280), Expect = 2e-24
Identities = 201/827 (24%), Positives = 308/827 (37%), Gaps = 117/827 (14%)
Query: 75 LEVQESGEYRCQAQGSPLSSPVHLDFSSASLIL---------QAPLSVFEGDSVVLRCRA 125
L +Q+ G Y C+A S+ D A LI+ P+ V L C+
Sbjct: 3613 LTIQDRGVYSCKA-----SNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQV 3667
Query: 126 KAEVTLNNTIYKN--------DNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVS 177
+ + T K+ D + F +K IP A LKD+G Y CT E+
Sbjct: 3668 DEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSC 3727
Query: 178 SNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGL 237
S TV ++ F + V S+ + G L C+ L+ S V ++ +F++++ L
Sbjct: 3728 SATVTVREPPSFVKKV--DPSYLMLPGESARLHCK----LKGSPV-IQVTWFKNNKELSE 3780
Query: 238 GWSLSPNF-------QITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLT 290
++ F IT + +DSG Y C+A V SDS + I ++ P S + T
Sbjct: 3781 SNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVN---DVGSDSCSTEIVIKEPPSF-IKT 3836
Query: 291 LSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASI----SFSLT 346
L P + GT L CE + F + K R S+ FS
Sbjct: 3837 LEPADIV--RGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFN 3894
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRG 406
+ + G Y C N +G A L + P + +DLI G + A RG
Sbjct: 3895 SADVGEYECVVANEVGKCGCMATHL-----LKEPPTFVKKVDDLIALGGQTVTLQAAVRG 3949
Query: 407 SLPILYQFHHEGAALE-----RRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKA 461
S PI + + + S ++ V I + G Y C A+N G Q S
Sbjct: 3950 SEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVG 4009
Query: 462 VSLSVTVPVSHPVLTLSSAEAL-TFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTP 520
+ V P + AE + G TL V G+P++ ++Y + PL +S
Sbjct: 4010 ELI-----VKEPAKIIERAELIQVTAGDPATLEYTV-AGTPELKPKWYKDGRPLVASKK- 4062
Query: 521 SVGRVSF-------SFSLTEGH-SGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRV 572
R+SF F E H SG Y N G E + ++ P T +
Sbjct: 4063 --YRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIA-PFFTKPL 4119
Query: 573 PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSS---APSGGEASFN-LSLTAEH 628
+VV L C+ P + WF S A G AS + +
Sbjct: 4120 RNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMND 4179
Query: 629 SGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSP 688
+GN++C A N + ++ S S + V P P ++ V+ +GS+P
Sbjct: 4180 AGNFTCRATNSVGSKDS-----SGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTP 4234
Query: 689 I-LYWFYHEDVTLGKISAPSGGG---------ASFNLSLT-TEHSGIYSCEADN---GLE 734
+ + WF G SGG +S L L T SG Y+C+ N G+E
Sbjct: 4235 LTIRWF------KGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVE 4288
Query: 735 AQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLG 794
L V P + + P GD +L C+ + G+P I +F D +
Sbjct: 4289 CS----ANLFVKEPAT--FVEKLEPSQLLKKGDATQLACK-VTGTPPIKITWFANDREIK 4341
Query: 795 NRSS-----PSGGASLNLS-LTAEHSGNYSCEADNGLGAQRSETVTL 835
S A L L+ + E SG Y CEA N G+ ++ +
Sbjct: 4342 ESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 4388
Score = 90.1 bits (222), Expect = 9e-18
Identities = 205/905 (22%), Positives = 347/905 (38%), Gaps = 117/905 (12%)
Query: 16 QFARTPRPIIFLQPPWTTVFQGE-------RVTLTCKGFRFYSPQKTKWYHRYLGKEILR 68
QF + P P++ L+ +T F+ + RV+ G + QK H + L
Sbjct: 4862 QFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQK----HGISFIDGLA 4917
Query: 69 ETPDNILEVQESGEYRCQAQ--GSPLSSPVHLDFSSASLILQ--APLSVFEGDSVVLRCR 124
+ V+ SG Y C+A+ S + L ++ P+ V + V L C
Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECE 4977
Query: 125 AKAEVTLNNTIYKNDNVLAFLNKRT--------DFHIPHACLKDNGAYRCTGYKESCCPV 176
T KN+ + K T + HI D G Y+C E
Sbjct: 4978 VTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCS 5037
Query: 177 SSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLG 236
S V ++ F + + ++ V + T S P+ + +DDQ L
Sbjct: 5038 CSTRVALKEPPSFIKKIENTTT--------VLKSSATFQSTVAGSPPISITWLKDDQILD 5089
Query: 237 LGWSLSPNF-------QITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVL 289
++ +F QI ++ + SG Y C+A + +++ VQ PA
Sbjct: 5090 EDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKN---ESGVERCYAFLLVQEPAQ---- 5142
Query: 290 TLSPEKALNFEGTK---VTLHC---ETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISF 343
EKA + + T+ +TL C T E ++ L + + VP R+ S+ E + SF
Sbjct: 5143 --IVEKAKSVDVTEKDPMTLECVVAGTPELKVKWL-KDGKQIVPSRYFSMSFENNVA-SF 5198
Query: 344 ---SLTTENSGNYYCTADNGLGAKPSKAV--SLSVTVPVSHPVLNLSSPEDLIFEGAKVT 398
S+ ++SG Y +N G+ A L +P S L+ + ++ G+ +
Sbjct: 5199 RIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSF-TKKLTKMDKVL--GSSIH 5255
Query: 399 LHCEAQRGSLPILYQFHHEG----AALERRSANSAGGVAISF-SLTAEHSGNYYCTADNG 453
+ C+ GSLPI Q+ +G + + R V++ +L E + NY C N
Sbjct: 5256 MECKVS-GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNV 5314
Query: 454 FGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMP 513
G + L+V P P + +TV + +G+P +++ +D+
Sbjct: 5315 AGDDACSGI-LTVKEP---PSFLVKPGRQQAIPDSTVEFKA-ILKGTPPFKIKWFKDDVE 5369
Query: 514 LWSSSTPSV---GRVSF--SFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPIL 568
L S + G SF +S+ +G Y C N G S L VT P P
Sbjct: 5370 LVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSD-SCTTMLLVTEP---PKF 5425
Query: 569 TLRVPRAQAV-VGDLLELHCEAPRGSPPI-LYWFYHEDVTLGSSS-----APSGGEASFN 621
++ ++ V GD L C+ GSP I + WF +E S S N
Sbjct: 5426 VKKLEASKIVKAGDSSRLECKI-AGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMN 5484
Query: 622 LSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCE 681
+L+ E SG++ CEA N S + S VIV P+ + P + + + L CE
Sbjct: 5485 -NLSTEDSGDFICEAQN---PAGSTSCSTKVIVK-EPPVFSSFPPIVETLKNAEVSLECE 5539
Query: 682 ALRGSSPILYWFYHEDVTLG-----KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQ 736
L G+ P +Y + L KI++ + + L++ T G Y C+A N + +
Sbjct: 5540 -LSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSD 5598
Query: 737 RSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNR 796
+ T+K+ P P + G+ EL ++ G+ I ++ E +
Sbjct: 5599 TC-VCTVKLKEP---PRFVSKLNSLTVVAGEPAELQA-SIEGAQPIFVQWLKEKEEVIRE 5653
Query: 797 SS------PSGGASLNLS-LTAEHSGNYSCEADNGLGAQRSETVTLYI--TGLTANRSGP 847
S A+L + ++G Y C+ N G R TL + + ++GP
Sbjct: 5654 SENIRITFVENVATLQFAKAEPANAGKYICQIKND-GGMRENMATLMVLEPAVIVEKAGP 5712
Query: 848 FATGV 852
V
Sbjct: 5713 MTVTV 5717
Score = 87.8 bits (216), Expect = 4e-17
Identities = 207/911 (22%), Positives = 334/911 (36%), Gaps = 150/911 (16%)
Query: 13 VSGQFARTPRPIIF---LQPPWTTVFQGERVTLTCKGFRFYSPQKT-KWYHRYLGKEILR 68
V G T P F L+P V G+ V+L C+ +P+ T WY G LR
Sbjct: 6068 VCGALVSTLEPPYFVTELEPLEAAV--GDSVSLQCQVAG--TPEITVSWYK---GDTKLR 6120
Query: 69 ETPD--------------NILEVQESGEYRCQAQ---GSPLSSPV------HLDFSSASL 105
TP+ N + + +SGEY C+A+ G+ S V L S A
Sbjct: 6121 PTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQ 6180
Query: 106 ILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVL--------AFLNKRTDFHIPHAC 157
+ +V G V L CR + Y++ +L +F++ I
Sbjct: 6181 LKDIEQTV--GLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTD 6238
Query: 158 LKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPV--LRASSFQPISGNPVTLTCETQL 215
L +G Y C+ + +S++ ++ +EP P ++ S I+G C
Sbjct: 6239 LSHSGQYSCSA--SNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHV-- 6294
Query: 216 SLERSDVPLRFRFFRDDQTLGLGWSL-------SPNFQITAMWSKDSGFYWCKAATMPYS 268
P+R + +D++ + G + +P+ +I + DSG Y C+A
Sbjct: 6295 ---TGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQAT----- 6346
Query: 269 VISDSPRSWIQVQIPASHP---VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEG 325
+D + Q+ P V L K +G + L C+ + F ++
Sbjct: 6347 --NDVGKDMCSAQLSVKEPPKFVKKLEASKVAK-QGESIQLECKISGSPEIKVSWFRNDS 6403
Query: 326 VPLRHKSVRCERGASISFSLTT------ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSH 379
H+S + S +L T E+SG+Y C A NG+G S + +L+V P
Sbjct: 6404 E--LHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG-DASCSTALTVKAP--- 6457
Query: 380 PVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAIS---- 435
PV +G+ V L CE G+ P + +R+ ++ I+
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEIS-GTPPFEVVW-----VKDRKQVRNSKKFKITSKHF 6511
Query: 436 ------FSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGAT 489
+L A G Y+C A N G S S SV P ++ T G
Sbjct: 6512 DTSLHILNLEASDVGEYHCKATNEVG---SDTCSCSVKFK-EPPRFVKKLSDTSTLIGDA 6567
Query: 490 VTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG-----HSGNYYCTAD 544
V L V+ P + + S + + +L G +SG Y C
Sbjct: 6568 VELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIK 6627
Query: 545 NGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAV-VGDLLELHCEAPRGSPPILYWFYHE 603
N G + V + V P + P V G+ L C G+P + ++ +
Sbjct: 6628 NDAGMRECSAV-----LTVLEPARIIEKPEPMTVTTGNPFALEC-VVTGTPELSAKWFKD 6681
Query: 604 DVTLGSSSAPS----GGEASFNLSLT-AEHSGNYSCEANNGLVAQHSDTISLSVIVPVSR 658
L + S AS + G YS E N V + + T+S+ V +
Sbjct: 6682 GRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNS-VGKSNCTVSVHVSDRIVP 6740
Query: 659 PILTFRAPRAQAVVGDLLELHCEALRGSSPI-LYWFY--HEDVTLGKI-SAPSGGGASFN 714
P + A++G + L C + GS+PI + WF +E V+ K S+ S + N
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECR-VSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 6799
Query: 715 LS-LTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHC 773
LS L +GIY+C A N + V + V P + P + + +
Sbjct: 6800 LSLLEPSDTGIYTCVAANVAGSDECSAV-----LTVQEPPSFEQTPDSVEVLPGMSLTFT 6854
Query: 774 EALRGSPLILYRFFHEDVTLGNRSSPSGGASLNLSL------------TAEHSGNYSCEA 821
+RG+P ++F G+R G S N+SL SG+YSC
Sbjct: 6855 SVIRGTPPFKVKWFK-----GSRELVP-GESCNISLEDFVTELELFEVQPLESGDYSCLV 6908
Query: 822 DNGLGAQRSET 832
N G+ T
Sbjct: 6909 TNDAGSASCTT 6919
Score = 87.0 bits (214), Expect = 8e-17
Identities = 144/568 (25%), Positives = 221/568 (38%), Gaps = 57/568 (10%)
Query: 301 GTKVTLHCETQEDSLRTLYRFYHEGVPLR----HKSVRCERGASISFSLTTEN-SGNYYC 355
G V+L C+ T+ +Y LR +++ A++ F+ N SG Y C
Sbjct: 6093 GDSVSLQCQVAGTPEITV-SWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 6151
Query: 356 TADNGLGAKPSKAVSL--SVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQ 413
A+N +G SK V +P S L E + G VTL C GS PI
Sbjct: 6152 KAENSIGTASSKTVFRIQERQLPPSF-ARQLKDIEQTV--GLPVTLTCRLN-GSAPIQVC 6207
Query: 414 FHHEGAAL---ERRSANSAGGVAISFSLTAE--HSGNYYCTADNGFGPQRSKAVSLSVTV 468
++ +G L E + VA L + HSG Y C+A N G S A L+
Sbjct: 6208 WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA-RLTARE 6266
Query: 469 PVSHPVLTLSSAEALTFEGATVTLHCEVQRGSP-QILYQFYHEDM-PLWSSSTPSVGRVS 526
P P + G + C V P +I + ++++ P + + VG
Sbjct: 6267 PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 6326
Query: 527 FS--FSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVV--GDL 582
+ +G SG Y C A N G + V P ++ A V G+
Sbjct: 6327 HLRILKVGKGDSGQYTCQATNDVGKDMCSA-----QLSVKEPPKFVKKLEASKVAKQGES 6381
Query: 583 LELHCEAPRGSPPI-LYWF-----YHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEA 636
++L C+ GSP I + WF HE S S + N +AE SG+Y CEA
Sbjct: 6382 IQLECKIS-GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTIN-EASAEDSGDYICEA 6439
Query: 637 NNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPI-LYWFYH 695
+NG V S + +L+V P P+ T + A+ G + L CE + G+ P + W
Sbjct: 6440 HNG-VGDASCSTALTVKAP---PVFTQKPSPVGALKGSDVILQCE-ISGTPPFEVVWVKD 6494
Query: 696 EDVTLG----KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSR 751
KI++ + L+L G Y C+A N + + ++K P
Sbjct: 6495 RKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSC-SVKFKEP--- 6550
Query: 752 PVLTLRAPGTHAAVGDLLELHC--EALRGSPLILYRFFHEDVTLGNRSSPS---GGASLN 806
P + T +GD +EL E + ++ + E + + S A+L
Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ 6610
Query: 807 L-SLTAEHSGNYSCEADNGLGAQRSETV 833
L S A +SG Y C+ N G + V
Sbjct: 6611 LGSPEASNSGKYICQIKNDAGMRECSAV 6638
Score = 85.5 bits (210), Expect = 2e-16
Identities = 204/888 (22%), Positives = 317/888 (35%), Gaps = 145/888 (16%)
Query: 34 VFQGERVTLTCKGFRFYSPQKTKWY----HRYLGKEILRETPDNI-------LEVQESGE 82
V QG+ TL K F KW+ LG + D + E ++SGE
Sbjct: 4590 VTQGDPATLQVK-FSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGE 4648
Query: 83 YRCQAQGSPLSSPVHLDFSSASLILQAP-------LSVFEGDSVVLRCRAKAEVTLNNTI 135
Y + Q S + LI+ + +G + L C ++
Sbjct: 4649 YTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQW 4708
Query: 136 YKNDNVLAFLNK-RTDFHIPHACLK-------DNGAYRCTGYKESCCPVSSNTVKIQVQE 187
+K+D ++ K + FH A L+ D+G Y C+ ++ S + ++
Sbjct: 4709 FKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK--- 4765
Query: 188 PFTRPVLRASSFQPISGNPVTLTCETQL-SLERSDVPLRFRFFRDDQTLGLG-----WS- 240
P Q NP T QL +L P+ ++F+D++ L G W
Sbjct: 4766 ---EPPYFVEKPQSQDVNPNT---RVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKD 4819
Query: 241 -LSPNFQITAMWSKDSGFYWCK------AATMPYSVISDSPRSWIQVQIPASHPVLTLSP 293
S + ++ A + DSG Y C+ AT ++ P +I+ PVL L
Sbjct: 4820 DTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIK----KPSPVLVLR- 4874
Query: 294 EKALNFEGTKVTLHCE-TQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTT----- 347
G T C+ T +R + Y +G + + + G S L T
Sbjct: 4875 ------NGQSTTFECQITGTPKIRVSW--YLDGNEI---TAIQKHGISFIDGLATFQISG 4923
Query: 348 ---ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL-IFEGAKVTLHCEA 403
ENSG Y C A N G S S+ + V P + + + + + + V L CE
Sbjct: 4924 ARVENSGTYVCEARNDAGT-----ASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEV 4978
Query: 404 QRGSLPILYQFHHEGAALERRSANSAGGVAISFSL-----TAEHSGNYYCTADNGFGPQR 458
G+ P + + + F+L +G Y C N G
Sbjct: 4979 T-GTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGG--- 5034
Query: 459 SKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILY------QFYHEDM 512
+ S S V + P + E T + GSP I Q ED
Sbjct: 5035 --SCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDD 5092
Query: 513 PLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRV 572
++ S SV + S+ GHSG Y C A N G +R L V P + +
Sbjct: 5093 NVYISFVDSVATLQIR-SVDNGHSGRYTCQAKNESGVERC-YAFLLVQEPAQ---IVEKA 5147
Query: 573 PRAQAVVGDLLELHCEAPRGSPPI-LYWFYHEDVTLGS---SSAPSGGEASFNL-SLTAE 627
D + L C G+P + + W + S S + ASF + S+ +
Sbjct: 5148 KSVDVTEKDPMTLEC-VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQ 5206
Query: 628 HSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSS 687
SG Y+ + N + D L V+ P T + + V+G + + C+ + GS
Sbjct: 5207 DSGQYTFKVENDFGSSSCDAY-LRVLDQNIPPSFTKKLTKMDKVLGSSIHMECK-VSGSL 5264
Query: 688 PI-LYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVA 746
PI WF K A + L H S E +N LE + + T KV+
Sbjct: 5265 PISAQWF--------KDGKEISTSAKYRLVC---HERSVSLEVNN-LELEDTANYTCKVS 5312
Query: 747 -----------VPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGN 795
+ V P L PG A+ D L+G+P ++F +DV L
Sbjct: 5313 NVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVEL-- 5370
Query: 796 RSSP------SGGAS-LNL-SLTAEHSGNYSCEADNGLGAQRSETVTL 835
S P G S LNL S+ A +G Y+C N +G+ T+ L
Sbjct: 5371 VSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL 5418
Score = 84.3 bits (207), Expect = 5e-16
Identities = 184/814 (22%), Positives = 297/814 (36%), Gaps = 94/814 (11%)
Query: 76 EVQESGEYRCQAQ---GSPLSSPVHLDFSSASLILQA-PLSVFEGDSVVLRCRAKAEVTL 131
E SG+Y CQ + G S V A +I + P++V G+ L C L
Sbjct: 6615 EASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPEL 6674
Query: 132 NNTIYKNDNVLA--------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKI 183
+ +K+ L+ F+NK IP A + D G Y ++ S+ TV +
Sbjct: 6675 SAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFE--VKNSVGKSNCTVSV 6732
Query: 184 QVQEPFTRP--VLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSL 241
V + P + + I G V L C S P+ +F+D + G
Sbjct: 6733 HVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS-----APISVGWFQDGNEIVSGPKC 6787
Query: 242 SPNFQ-------ITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPE 294
+F ++ + D+G Y C AA + S D + + VQ P S S E
Sbjct: 6788 QSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGS---DECSAVLTVQEPPSFEQTPDSVE 6844
Query: 295 KALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASIS--FSLTTENSGN 352
T ++ T ++ ++ E VP ++ E + F + SG+
Sbjct: 6845 VLPGMSLTFTSVIRGTPPFKVKW-FKGSRELVPGESCNISLEDFVTELELFEVQPLESGD 6903
Query: 353 YYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFE-GAKVTLHCEAQRGSLPIL 411
Y C N G+ S + + V P + D E G+ + L G+ PI
Sbjct: 6904 YSCLVTNDAGS-----ASCTTHLFVKEPATFVKRLADFSVETGSPIVLEA-TYTGTPPIS 6957
Query: 412 YQFHHEGAALERRSANSAGGVAISFSL-----TAEHSGNYYCTADNGFGPQRSKAVSLSV 466
+ + + + S S L T E Y C +N G +A+ +SV
Sbjct: 6958 VSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEAL-VSV 7016
Query: 467 TVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVS 526
P + + L EA+ E AT L C+V G+P+I +Y E L S+ + +
Sbjct: 7017 LEP-PYFIEPLEHVEAVIGEPAT--LQCKVD-GTPEIRISWYKEHTKLRSAPAYKMQFKN 7072
Query: 527 FSFSLTEG---HS--GNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGD 581
SL HS G Y C ADN G S V L + P ++ +G
Sbjct: 7073 NVASLVINKVDHSDVGEYSCKADNSVGAVASSAV-LVIKARKLPPFFARKLKDVHETLGF 7131
Query: 582 LLELHCEAPRGSPPILYWF-----YHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEA 636
+ C P + W+ +D L +S + L H G Y+C A
Sbjct: 7132 PVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI-LQTDQSHIGQYNCSA 7190
Query: 637 NNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHE 696
+N L S + L + P + +G+ C + G++PI
Sbjct: 7191 SNPL-GTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCH-VTGTAPI------- 7241
Query: 697 DVTLGKISAPSGGGASFNLSLTTE------------HSGIYSCEADNGLEAQRSEMVTLK 744
+T K + G ++ ++L +G Y+C A N + + S L
Sbjct: 7242 KITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASN-IAGKDSCSAQLG 7300
Query: 745 VAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS-----P 799
V P R + L P + C+ + GSP I ++ ++ + S
Sbjct: 7301 VQEP-PRFIKKLE-PSRIVKQDEFTRYECK-IGGSPEIKVLWYKDETEIQESSKFRMSFV 7357
Query: 800 SGGASLNL-SLTAEHSGNYSCEADNGLGAQRSET 832
A L + +L+ E SG+Y+CEA N G+ S T
Sbjct: 7358 DSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391
Score = 83.2 bits (204), Expect = 1e-15
Identities = 176/822 (21%), Positives = 302/822 (36%), Gaps = 121/822 (14%)
Query: 79 ESGEYRCQAQGSPLSSPVHLDFSSASLILQAP---LSVFEGDSVVLR-------CRAKAE 128
++G+Y C A S+ D SA L +Q P + E +V + C+
Sbjct: 7278 DAGQYTCYA-----SNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGS 7332
Query: 129 VTLNNTIYKNDNVL--------AFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNT 180
+ YK++ + +F++ + + ++D+G Y C + + SS +
Sbjct: 7333 PEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTS 7392
Query: 181 VKIQVQEPFTRPVLRAS--SFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLG 238
+K V+EP P+ R + + G V L CE Q P +++D + L G
Sbjct: 7393 LK--VKEP---PIFRKKPHPIETLKGADVHLECELQ-----GTPPFHVSWYKDKRELRSG 7442
Query: 239 WS---LSPNF----QITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTL 291
+S NF I + + D G Y CKA V SD+ I ++ P P
Sbjct: 7443 KKYKIMSENFLTSIHILNVDAADIGEYQCKATN---DVGSDTCVGSIALKAP---PRFVK 7496
Query: 292 SPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKS----VRCERGASISFS-LT 346
G +V L + ++ F +G +R E A++ FS +
Sbjct: 7497 KLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVE 7556
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL-IFEGAKVTLHCEAQR 405
N+G Y C N G + A T+ V P + PE + + G TL C
Sbjct: 7557 PANAGKYTCQIKNDAGMQECFA-----TLSVLEPATIVEKPESIKVTTGDTCTLECTV-A 7610
Query: 406 GSLPILYQFHHEGAALERRSA------NSAGGVAISFSLTAEHSGNYYCTADNGFGPQRS 459
G+ + ++ +G L + N G+ I ++ SG Y N G + S
Sbjct: 7611 GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKI-INVAPSDSGVYSFEVQNPVG-KDS 7668
Query: 460 KAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSST 519
SL V+ P T E G++V + C+V GSP I ++HE + S
Sbjct: 7669 CTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFHEGNEISSGRK 7727
Query: 520 PSVGRVSFSFSLT-----EGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPR 574
+ +LT E SG+Y C A N G + V P ++ P
Sbjct: 7728 YQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECS-----APLTVREPPSFVQKPD 7782
Query: 575 AQAVVGDLLELHCEAPRGSPPI-LYWFYHEDVTLGSSSAPSGGEASFNL----------S 623
V+ +G+PP + WF GSS G + +L
Sbjct: 7783 PMDVLTGTNVTFTSIVKGTPPFSVSWF------KGSSELVPGDRCNVSLEDSVAELELFD 7836
Query: 624 LTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVS--RPILTFRAPRAQAVVGDLLELHCE 681
+ SG Y+C +N + S T L + P + + + + + ++ +
Sbjct: 7837 VDTSQSGEYTCIVSNE-AGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILE------G 7889
Query: 682 ALRGSSPILYWFYHEDVTLG-----KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQ 736
G+ PI + + + I+ S T E +G Y+C +N A
Sbjct: 7890 TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIEN---AS 7946
Query: 737 RSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNR 796
+ + ++ + + P + +VGD L C+ L G+P I ++ D L
Sbjct: 7947 GKDSCSAQILI-LEPPYFVKQLEPVKVSVGDSASLQCQ-LAGTPEIGVSWYKGDTKLRPT 8004
Query: 797 SSPSGGASLNLS------LTAEHSGNYSCEADNGLGAQRSET 832
++ N++ + SG Y C+A+N +G + T
Sbjct: 8005 TTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAST 8046
Score = 82.0 bits (201), Expect = 2e-15
Identities = 190/825 (23%), Positives = 307/825 (37%), Gaps = 117/825 (14%)
Query: 73 NILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRAKAEVTLN 132
N L ++SG++ C+AQ +P S +I++ P VF ++ AEV+L
Sbjct: 5484 NNLSTEDSGDFICEAQ-----NPAGSTSCSTKVIVKEP-PVFSSFPPIVETLKNAEVSLE 5537
Query: 133 NTI----------YKNDNVL--------AFLNKRTDFHIPHACLKDNGAYRCTGYKESCC 174
+ YK+ L A N T HI + D G Y C E
Sbjct: 5538 CELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS 5597
Query: 175 PVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQT 234
TVK++ EP R V + +S ++G P E Q S+E + P+ ++ ++ +
Sbjct: 5598 DTCVCTVKLK--EP-PRFVSKLNSLTVVAGEPA----ELQASIEGAQ-PIFVQWLKEKEE 5649
Query: 235 LGLGWSLSPNFQITAMWS-----------KDSGFYWCKAATMPYSVISDSPRSWIQVQIP 283
+ S N +IT + + ++G Y C+ + +D +
Sbjct: 5650 V---IRESENIRITFVENVATLQFAKAEPANAGKYICQ-------IKNDGGMRENMATLM 5699
Query: 284 ASHPVLTLSPEKALNFE-GTKVTLHCE---TQEDSLRTLYRFYHEGVPL----RHKSVRC 335
P + + + G TL C+ T E S+ +Y +G L +HK
Sbjct: 5700 VLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVE----WYKDGKLLTSSQKHKFSFY 5755
Query: 336 ERGASISF-SLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEG 394
+ +S+ S+ +++G Y N +G AV + V+ P G
Sbjct: 5756 NKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAV-VDVSDRAVPPSFTRRLKNTGGVLG 5814
Query: 395 AKVTLHCEAQRGSLPILYQFHHE------GAALERRSANSAGGVAISFSLTAEHSGNYYC 448
A L C+ GS PI + HE GA + +++ + ++ SL + GNY C
Sbjct: 5815 ASCILECKVA-GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLN-SLDSSDMGNYTC 5872
Query: 449 TADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFY 508
A N G +AV L+V P S V E L + T T V RG+P ++
Sbjct: 5873 VAANVAGSDECRAV-LTVQEPPSF-VKEPEPLEVLPGKNVTFT---SVIRGTPPFKVNWF 5927
Query: 509 HEDMPLWSSST------PSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVP 562
L +V + F++ SG Y C N G Q S LFV P
Sbjct: 5928 RGARELVKGDRCNIYFEDTVAELEL-FNIDISQSGEYTCVVSNNAG-QASCTTRLFVKEP 5985
Query: 563 VSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFN- 621
+ R+ G + L G+ PI + + + +S +
Sbjct: 5986 AA---FLKRLSDHSVEPGKSIILE-STYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTC 6041
Query: 622 ----LSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLE 677
L+ T +G YSCE N + + +++ + P +A VGD +
Sbjct: 6042 ILEILNSTKRDAGQYSCEIEN----EAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVS 6097
Query: 678 LHCEALRGSSPILYWFYHEDVTLGKIS------APSGGGASFNLSLTTEHSGIYSCEADN 731
L C+ + G+ I +Y D L + FN + SG Y+C+A+N
Sbjct: 6098 LQCQ-VAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFN-KVNINDSGEYTCKAEN 6155
Query: 732 GLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDV 791
+ S+ V ++ P + VG + L C L GS I ++ + V
Sbjct: 6156 SIGTASSKTV-FRIQERQLPPSFARQLKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDGV 6213
Query: 792 TLGN-----RSSPSGGASLNLSLT-AEHSGNYSCEADNGLGAQRS 830
L + S A+L + T HSG YSC A N LG S
Sbjct: 6214 LLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASS 6258
Score = 80.5 bits (197), Expect = 7e-15
Identities = 164/814 (20%), Positives = 294/814 (36%), Gaps = 102/814 (12%)
Query: 80 SGEYRCQAQGSPLSSPVHLDFSSASLILQAP---------LSVFEGDSVVLRCRAKAEVT 130
SG Y CQA+ ++ A L++Q P + V E D + L C
Sbjct: 5115 SGRYTCQAKNES-----GVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPE 5169
Query: 131 LNNTIYKNDNVL--------AFLNKRTDFHIPHACLKDNGAYRC---TGYKESCCPVSSN 179
L K+ + +F N F I +D+G Y + S C
Sbjct: 5170 LKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLR 5229
Query: 180 TVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGW 239
+ + FT+ + + + G+ + + C+ SL P+ ++F+D + +
Sbjct: 5230 VLDQNIPPSFTK---KLTKMDKVLGSSIHMECKVSGSL-----PISAQWFKDGKEISTSA 5281
Query: 240 SL-------SPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLS 292
S + ++ + +D+ Y CK + + D+ + V+ P P +
Sbjct: 5282 KYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGD---DACSGILTVKEP---PSFLVK 5335
Query: 293 PEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASIS------FSLT 346
P + + V + + +++ + V L +C G S +S+
Sbjct: 5336 PGRQQAIPDSTVEFKAILKGTPPFKI-KWFKDDVELV-SGPKCFIGLEGSTSFLNLYSVD 5393
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRG 406
+G Y C N +G+ + L P L S ++ G L C+ G
Sbjct: 5394 ASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASK---IVKAGDSSRLECKIA-G 5449
Query: 407 SLPIL---YQFHHEGAALERRSANSAGGVAI--SFSLTAEHSGNYYCTADNGFGPQRSKA 461
S I ++ HE A ++ VA+ +L+ E SG++ C A N G +
Sbjct: 5450 SPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG-----S 5504
Query: 462 VSLSVTVPVSHPVLTLSSAEAL-TFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTP 520
S S V V P + S + T + A V+L CE+ G+P +Y + L SS
Sbjct: 5505 TSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELS-GTPPFEVVWYKDKRQLRSSKKY 5563
Query: 521 SVGRVSFSFSL-----TEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRA 575
+ +F S+ G Y+C A N G V ++ + P P ++
Sbjct: 5564 KIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTC-VCTVKLKEP---PRFVSKLNSL 5619
Query: 576 QAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSS------APSGGEASFNLSLTAEHS 629
V G+ EL P + W ++ + S + F + A ++
Sbjct: 5620 TVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPA-NA 5678
Query: 630 GNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPI 689
G Y C+ N + +L V+ P ++ +A VG+ L C+
Sbjct: 5679 GKYICQIKND-GGMRENMATLMVLEPA---VIVEKAGPMTVTVGETCTLECKVAGTPELS 5734
Query: 690 LYWFYHEDVTLG----KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKV 745
+ W+ + K S + + LS+ + +G Y+ + N + + S + V
Sbjct: 5735 VEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV-GKSSCTAVVDV 5793
Query: 746 AVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPSGGASL 805
+ P T R T +G L C+ SP+ + +FHE + + + S
Sbjct: 5794 SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISV-AWFHEKTKIVSGAKYQTTFSD 5852
Query: 806 NL------SLTAEHSGNYSCEADNGLGAQRSETV 833
N+ SL + GNY+C A N G+ V
Sbjct: 5853 NVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 5886
Score = 80.5 bits (197), Expect = 7e-15
Identities = 192/836 (22%), Positives = 312/836 (37%), Gaps = 111/836 (13%)
Query: 75 LEVQESGEYRCQAQGS--PLSSPVHLDFSSASLILQA--PLSVFEGDSVVLRCRAKAEVT 130
L V++SG+Y C+A + SS L + + P+ +G V L C +
Sbjct: 7368 LSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPP 7427
Query: 131 LNNTIYKNDNVLAFLNK--------RTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTV- 181
+ + YK+ L K T HI + D G Y+C + V S+T
Sbjct: 7428 FHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATND----VGSDTCV 7483
Query: 182 -KIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDD-----QTL 235
I ++ P R V + S + G V L Q ++E ++ P+ +F+D ++
Sbjct: 7484 GSIALKAP-PRFVKKLSDISTVVGKEVQL----QTTIEGAE-PISVVWFKDKGEIVRESD 7537
Query: 236 GLGWSLSPN---FQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHP-VLTL 291
+ S S N Q + + ++G Y C+ + +D+ + P +
Sbjct: 7538 NIWISYSENIATLQFSRVEPANAGKYTCQ-------IKNDAGMQECFATLSVLEPATIVE 7590
Query: 292 SPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISF-------- 343
PE G TL C T + +++ +G K + + ISF
Sbjct: 7591 KPESIKVTTGDTCTLEC-TVAGTPELSTKWFKDG-----KELTSDNKYKISFFNKVSGLK 7644
Query: 344 --SLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHC 401
++ +SG Y N +G K S SL V+ P E G+ V + C
Sbjct: 7645 IINVAPSDSGVYSFEVQNPVG-KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMEC 7703
Query: 402 EAQRGSLPILYQFHHEG----AALERRSANSAGGVAISFSLTAE-HSGNYYCTADNGFGP 456
+ GS PI + HEG + + ++ + A++ ++ E SG+Y C A N G
Sbjct: 7704 KVY-GSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGS 7762
Query: 457 QRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWS 516
A L+V P S V + LT T T + +G+P ++ L
Sbjct: 7763 DECSA-PLTVREPPSF-VQKPDPMDVLTGTNVTFT---SIVKGTPPFSVSWFKGSSELVP 7817
Query: 517 ------SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTL 570
S SV + F + SG Y C N G + S L++ P
Sbjct: 7818 GDRCNVSLEDSVAELEL-FDVDTSQSGEYTCIVSNEAG-KASCTTHLYIKAPAK---FVK 7872
Query: 571 RVPRAQAVVGDLLELHCEAPRGSPPILYWFYHE--DVTLGSSSAPSGGEASFNL---SLT 625
R+ G L L G+PPI + +VT + E S L S T
Sbjct: 7873 RLNDYSIEKGKPLILE-GTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSST 7931
Query: 626 AEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRG 685
E +G Y+C N A D+ S +++ + P + + VGD L C+ L G
Sbjct: 7932 VEDAGQYNCYIEN---ASGKDSCSAQILI-LEPPYFVKQLEPVKVSVGDSASLQCQ-LAG 7986
Query: 686 SSPILYWFYHED-----VTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEM 740
+ I +Y D T K+ + + SG Y C+A+N + + S
Sbjct: 7987 TPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSV-GEVSAS 8045
Query: 741 VTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPS 800
L V P + + VG + C A+ GS I ++ + L + SP+
Sbjct: 8046 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPL--KDSPN 8102
Query: 801 -------GGASLNLSLTAEH-SGNYSCEADNGLGAQRSETVTLYITGLTANRSGPF 848
A+LN+ T +G YSC A N +G+ S + LT ++ PF
Sbjct: 8103 VQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLI----LTEGKNPPF 8154
Score = 77.4 bits (189), Expect = 6e-14
Identities = 183/852 (21%), Positives = 303/852 (35%), Gaps = 126/852 (14%)
Query: 54 KTKWYHRYLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQ---AP 110
K ++++ G +I+ P +SG Y + Q +PV D +ASL + P
Sbjct: 7633 KISFFNKVSGLKIINVAPS------DSGVYSFEVQ-----NPVGKDSCTASLQVSDRTVP 7681
Query: 111 LSV---------FEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACL--- 158
S G SVV+ C+ ++ + + N ++ K + C
Sbjct: 7682 PSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTV 7741
Query: 159 -----KDNGAYRC-----TGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVT 208
D+G Y C G E P++ VQ+P VL +G VT
Sbjct: 7742 NMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVL--------TGTNVT 7793
Query: 209 LTCETQLSLERSDVPLRFRFFRDDQTLGLG----WSLSPNFQITAMWSKD---SGFYWCK 261
T S+ + P +F+ L G SL + ++ D SG Y C
Sbjct: 7794 FT-----SIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCI 7848
Query: 262 AATMPYSVISDSPRSWIQVQIPASHPV----LTLSPEKALNFEGTKVTLHCETQEDSLRT 317
+ S + + ++ PA ++ K L EGT T S+
Sbjct: 7849 VSNEAGKA---SCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGT----FTGTPPISVTW 7901
Query: 318 LYRFYHEGVPLRHKSVRCERGASISF-SLTTENSGNYYCTADNGLGAKPSKAVSLSVTVP 376
+ R E+ A + S T E++G Y C +N G S S +
Sbjct: 7902 KKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKD-----SCSAQIL 7956
Query: 377 VSHPVLNLSSPEDL-IFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSA-------NS 428
+ P + E + + G +L C Q P + ++G R + N+
Sbjct: 7957 ILEPPYFVKQLEPVKVSVGDSASLQC--QLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNN 8014
Query: 429 AGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGA 488
+ + + SG Y C A+N G + S + L+V P + + G
Sbjct: 8015 VATLVFN-QVDINDSGEYICKAENSVG-EVSASTFLTVQEQKLPPSFSRQLRDVQETVGL 8072
Query: 489 TVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFS-----FSLTEGHSGNYYCTA 543
V C + GS I +Y + PL S + + F +G Y CTA
Sbjct: 8073 PVVFDCAIS-GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTA 8131
Query: 544 DNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHE 603
N G S L +T + P +R+ AVVG+ + C P + W
Sbjct: 8132 TNPIGSASSSA-RLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSW---- 8186
Query: 604 DVTLGSSSAPSGGEASFNLSLTAEH----------SGNYSCEANNGLVAQHSDTISLSVI 653
S SGG+ + + H SG Y+C A N V + S T L++
Sbjct: 8187 --AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNE-VGKDSCTAQLNIK 8243
Query: 654 VPVSRPILTFR-APRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGAS 712
+ P T R + + G+ +L + GS PI +Y ++ + S +
Sbjct: 8244 ERLIPPSFTKRLSETVEETEGNSFKLEGR-VAGSQPITVAWYKNNIEIQPTSNCEITFKN 8302
Query: 713 FNLSLTTEHSG-----IYSCEADNGLEAQRSEMVTLKVAV--PVSRPVLTLRAPGTHAAV 765
L L +G +Y+C+ N S + T + + P PV +
Sbjct: 8303 NTLVLQVRKAGMNDAGLYTCKVSNDAG---SALCTSSIVIKEPKKPPVFDQHLTPVTVSE 8359
Query: 766 GDLLELHCEALRGSPL-ILYRFFHEDVTLGNRSS---PSGGASLNLSLTAE-HSGNYSCE 820
G+ ++L C P+ I + ++ +R S SG A L L A+ SG+Y C+
Sbjct: 8360 GEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCK 8419
Query: 821 ADNGLGAQRSET 832
A N G+ +++
Sbjct: 8420 ASNVAGSDTTKS 8431
Score = 76.6 bits (187), Expect = 1e-13
Identities = 195/841 (23%), Positives = 311/841 (36%), Gaps = 131/841 (15%)
Query: 79 ESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVF----------EGDSVVLRCRAKAE 128
+SG+Y CQA ++ V D SA L ++ P +G+S+ L C+
Sbjct: 6337 DSGQYTCQA-----TNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGS 6391
Query: 129 VTLNNTIYKNDNVL--------AFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNT 180
+ + ++ND+ L +F+N I A +D+G Y C + S
Sbjct: 6392 PEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTA 6451
Query: 181 VKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWS 240
+ ++ FT+ + S + G+ V L CE P + +D + +
Sbjct: 6452 LTVKAPPVFTQ---KPSPVGALKGSDVILQCEIS-----GTPPFEVVWVKDRKQV----R 6499
Query: 241 LSPNFQITA-----------MWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVL 289
S F+IT+ + + D G Y CKA V SD+ ++ + P V
Sbjct: 6500 NSKKFKITSKHFDTSLHILNLEASDVGEYHCKATN---EVGSDTCSCSVKFKEPPRF-VK 6555
Query: 290 TLSPEKALNFEGTKVTLHCET-QEDSLRTLYRFYHEGVPLRHKSVRCERGASISF----- 343
LS L + ++ E Q S+ L R + +R ISF
Sbjct: 6556 KLSDTSTLIGDAVELRAIVEGFQPISVVWLKD--------RGEVIRESENTRISFIDNIA 6607
Query: 344 -----SLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL-IFEGAKV 397
S NSG Y C N G + AV + V P + PE + + G
Sbjct: 6608 TLQLGSPEASNSGKYICQIKNDAGMRECSAV-----LTVLEPARIIEKPEPMTVTTGNPF 6662
Query: 398 TLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLT---AEHS--GNYYCTADN 452
L C G+ + ++ +G L S + + SL AE S G Y N
Sbjct: 6663 ALECVVT-GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKN 6721
Query: 453 GFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDM 512
G VS+ V+ + P + GA+V L C V GS I ++ +
Sbjct: 6722 SVGKSNC-TVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVS-GSAPISVGWFQDGN 6779
Query: 513 PLWSS----STPSVGRVSFSFSLTE-GHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPI 567
+ S S+ S + + SL E +G Y C A N G V + V P
Sbjct: 6780 EIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV-----LTVQEPP 6834
Query: 568 LTLRVPRAQAVVGDLLELHCEAPRGSPPI-LYWFY-HEDVTLGSSSAPSGGEASFNLSLT 625
+ P + V+ + RG+PP + WF ++ G S S + L L
Sbjct: 6835 SFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELF 6894
Query: 626 AEH---SGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA 682
SG+YSC LV + + S + + V P TF A V + EA
Sbjct: 6895 EVQPLESGDYSC-----LVTNDAGSASCTTHLFVKEPA-TFVKRLADFSVETGSPIVLEA 6948
Query: 683 L-RGSSPILYWFYHEDVTLGK-----ISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQ 736
G+ PI + ++ + + I+ L T E YSC +N +
Sbjct: 6949 TYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIEN----E 7004
Query: 737 RSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNR 796
+ + + + P A +G+ L C+ + G+P I ++ E L R
Sbjct: 7005 AGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCK-VDGTPEIRISWYKEHTKL--R 7061
Query: 797 SSPS-------GGASLNLSLTAEHS--GNYSCEADNGLGAQRSETVTLYITGLTANRSGP 847
S+P+ ASL ++ +HS G YSC+ADN +GA S V + + A + P
Sbjct: 7062 SAPAYKMQFKNNVASLVIN-KVDHSDVGEYSCKADNSVGAVASSAVLV----IKARKLPP 7116
Query: 848 F 848
F
Sbjct: 7117 F 7117
Score = 72.8 bits (177), Expect = 1e-12
Identities = 186/827 (22%), Positives = 307/827 (37%), Gaps = 121/827 (14%)
Query: 75 LEVQESGEYRCQAQ---GSPLSSPVHLDFSSASLI--LQAPLSVFEGDSVVLRCRAKAEV 129
++ ++G+Y C GS + + L + L+A V GDS L C+
Sbjct: 5392 VDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSP 5451
Query: 130 TLNNTIYKNDNVL--------AFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTV 181
+ ++N++ L F++ + + +D+G + C ++ +S +
Sbjct: 5452 EIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEA--QNPAGSTSCST 5509
Query: 182 KIQVQEPFTRPVLRASSFQPI----SGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGL 237
K+ V+EP PV SSF PI V+L CE P +++D + L
Sbjct: 5510 KVIVKEP---PVF--SSFPPIVETLKNAEVSLECELS-----GTPPFEVVWYKDKRQLRS 5559
Query: 238 GWSL---SPNFQ----ITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLT 290
S NF I + + D G Y CKA V SD+ ++++ P V
Sbjct: 5560 SKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN---EVGSDTCVCTVKLKEPPRF-VSK 5615
Query: 291 LSPEKALNFEGTKVTLHCETQEDS----LRTLYRFYHEGVPLRHKSVRCERGASISFSLT 346
L+ + E ++ E + L+ E +R V E A++ F+
Sbjct: 5616 LNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFV--ENVATLQFAKA 5673
Query: 347 TE-NSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL-IFEGAKVTLHCEAQ 404
N+G Y C N G + + A T+ V P + + + + G TL C+
Sbjct: 5674 EPANAGKYICQIKNDGGMRENMA-----TLMVLEPAVIVEKAGPMTVTVGETCTLECKVA 5728
Query: 405 RGSLPILYQFHHEGAALERRSA------NSAGGVAISFSLTAEHSGNYYCTADNGFGPQR 458
G+ + +++ +G L N + I S+ + +G Y N G
Sbjct: 5729 -GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRI-LSVERQDAGTYTFQVQNNVGKSS 5786
Query: 459 SKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSS 518
AV + V+ P T GA+ L C+V SP I ++HE + S +
Sbjct: 5787 CTAV-VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSP-ISVAWFHEKTKIVSGA 5844
Query: 519 ------TPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRV 572
+ +V + + SL GNY C A N G V + V P ++
Sbjct: 5845 KYQTTFSDNVCTLQLN-SLDSSDMGNYTCVAANVAGSDECRAV-----LTVQEPPSFVKE 5898
Query: 573 PRAQAVVGDLLELHCEAPRGSPPI-LYWFYHEDVTLGSSSAPSGGEAS------------ 619
P V+ RG+PP + WF G+ G +
Sbjct: 5899 PEPLEVLPGKNVTFTSVIRGTPPFKVNWFR------GARELVKGDRCNIYFEDTVAELEL 5952
Query: 620 FNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELH 679
FN+ ++ SG Y+C +N Q S T L V P + R G + L
Sbjct: 5953 FNIDIS--QSGEYTCVVSNN-AGQASCTTRLFVKEPAA---FLKRLSDHSVEPGKSIILE 6006
Query: 680 CEALRGSSPILYWFYHEDVTLG-----KISAPSGGGASFNLSLTTEHSGIYSCEADNGLE 734
G+ PI + + + I L+ T +G YSCE +N E
Sbjct: 6007 -STYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIEN--E 6063
Query: 735 AQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLG 794
A R V + + P AAVGD + L C+ + G+P I ++ D L
Sbjct: 6064 AGRD--VCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQ-VAGTPEITVSWYKGDTKL- 6119
Query: 795 NRSSP-------SGGASLNLS-LTAEHSGNYSCEADNGLGAQRSETV 833
R +P + A+L + + SG Y+C+A+N +G S+TV
Sbjct: 6120 -RPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTV 6165
Score = 72.4 bits (176), Expect = 2e-12
Identities = 193/911 (21%), Positives = 331/911 (36%), Gaps = 169/911 (18%)
Query: 14 SGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR----------YLG 63
SG P +P V G V L F+ +P +W+ Y+
Sbjct: 4197 SGALIVQEPPSFVTKPGSKDVLPGSAVCLKST-FQGSTPLTIRWFKGNKELVSGGSCYIT 4255
Query: 64 KEILRETPD-NILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFE------- 115
KE L + + +++ +SG Y C+ S ++ V SA+L ++ P + E
Sbjct: 4256 KEALESSLELYLVKTSDSGTYTCKV--SNVAGGVEC---SANLFVKEPATFVEKLEPSQL 4310
Query: 116 ---GDSVVLRCRAKAEVTLNNTIYKNDNVL--------AFLNKRTDFHIPHACLKDNGAY 164
GD+ L C+ + T + ND + +F+ + ++D+G Y
Sbjct: 4311 LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEY 4370
Query: 165 RCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDV-P 223
C E+ S+ V ++ FT+ F+PI V + L E + P
Sbjct: 4371 MCEAQNEAGSDHCSSIVIVKESPYFTK------EFKPIE---VLKEYDVMLLAEVAGTPP 4421
Query: 224 LRFRFFRDDQTLGLGWSLSP-------NFQITAMWSKDSGFYWCKAATMPYSVISDS--- 273
+F+D+ L G + QI + D+G Y C+ S I +
Sbjct: 4422 FEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVT 4481
Query: 274 ---PRSWIQVQIPASHPV--------LTLSPEKALNFEGTKVTLHCETQEDSLRTLYR-- 320
P S+I+ +I ++ + TL + K + T++D++R +
Sbjct: 4482 LREPPSFIK-KIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEI-TEDDNIRMTFENN 4539
Query: 321 ---FYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPV 377
Y G+ ++H G Y C A N G + A+ LSV P
Sbjct: 4540 VASLYLSGIEVKH-------------------DGKYVCQAKNDAGIQRCSAL-LSVKEPA 4579
Query: 378 SHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALE-----RRSANSAGGV 432
+ + + + +G TL + G+ I ++ +G L + S +
Sbjct: 4580 T---ITEEAVSIDVTQGDPATLQVKFS-GTKEITAKWFKDGQELTLGSKYKISVTDTVSI 4635
Query: 433 AISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTL 492
S + SG Y N G KA ++V + P T + + +G+ + L
Sbjct: 4636 LKIISTEKKDSGEYTFEVQNDVGRSSCKA-RINVLDLIIPPSFTKKLKKMDSIKGSFIDL 4694
Query: 493 HCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSF---------SLTEG-HSGNYYCT 542
C + GS I Q++ +D + +S + FSF S EG SG Y C+
Sbjct: 4695 EC-IVAGSHPISIQWFKDDQEISASE-----KYKFSFHDNTAFLEISQLEGTDSGTYTCS 4748
Query: 543 ADNGFGPQRS------EVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPI 596
A N G + + FV P S+ + + +A+VG G+ P+
Sbjct: 4749 ATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVG-----------GTAPM 4797
Query: 597 LYWFYHEDVTLGSSSAPSGGEASFNLSL-----TAEHSGNYSCEANNGLVAQHSDTISLS 651
++ ++ L S +A S + + SL A SG Y C+ +N + T +
Sbjct: 4798 TIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDV-----GTATSK 4852
Query: 652 VIVPVSRPILTFRAPRAQAVV--GDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGG 709
+ V P + P V+ G C+ + G+ I +Y + +I+A
Sbjct: 4853 ATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQ-ITGTPKIRVSWYLDG---NEITAIQKH 4908
Query: 710 GASFNLSLTT--------EHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGT 761
G SF L T E+SG Y CEA N S + LKV P P
Sbjct: 4909 GISFIDGLATFQISGARVENSGTYVCEARND-AGTASCSIELKVKEP---PTFIRELKPV 4964
Query: 762 HAAVGDLLELHCEALRGSPL-ILYRFFHEDVTLGNRSSPSGGASL-NLSLT---AEHSGN 816
+EL CE P + + + ++ + + + S+ NL +T +G
Sbjct: 4965 EVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGE 5024
Query: 817 YSCEADNGLGA 827
Y C N G+
Sbjct: 5025 YQCIVSNEGGS 5035
Score = 66.2 bits (160), Expect = 1e-10
Identities = 170/820 (20%), Positives = 309/820 (37%), Gaps = 121/820 (14%)
Query: 75 LEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLS---------VFEGDSVVLRCRA 125
+++ ++G + C+A S S SS +LI+Q P S V G +V L+
Sbjct: 4175 VDMNDAGNFTCRATNSVGSKD-----SSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTF 4229
Query: 126 KAEVTLNNTIYKNDNVLA-----FLNKR---TDFHIPHACLKDNGAYRCTGYKESCCPVS 177
+ L +K + L ++ K + + D+G Y C +
Sbjct: 4230 QGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCK--VSNVAGGV 4287
Query: 178 SNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGL 237
+ + V+EP T S G+ L C+ P++ +F +D+ +
Sbjct: 4288 ECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVT-----GTPPIKITWFANDREIKE 4342
Query: 238 GWSLSPNF-------QITAMWSKDSGFYWCKAATMPYS-------VISDSP---RSWIQV 280
+F ++T + +DSG Y C+A S ++ +SP + + +
Sbjct: 4343 SSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPI 4402
Query: 281 QIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGAS 340
++ + V+ L+ GT +++++ R Y + S++
Sbjct: 4403 EVLKEYDVMLLA-----EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI----- 4452
Query: 341 ISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLH 400
++G Y C N +G+ A +++ P S + + S L G
Sbjct: 4453 --LKFVAADAGEYQCRVTNEVGSSICSA-RVTLREPPSF-IKKIESTSSL--RGGTAAFQ 4506
Query: 401 CEAQRGSLPILYQFHHEGAALERRS------ANSAGGVAISFSLTAEHSGNYYCTADNGF 454
+GSLPI + + + N+ + +S + +H G Y C A N
Sbjct: 4507 ATL-KGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLS-GIEVKHDGKYVCQAKNDA 4564
Query: 455 GPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPL 514
G QR A+ LSV P + +T + +G TL + G+ +I +++ + L
Sbjct: 4565 GIQRCSAL-LSVKEPAT---ITEEAVSIDVTQGDPATLQVKFS-GTKEITAKWFKDGQEL 4619
Query: 515 -----WSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ--RSEVVSLFVTVPVSRPI 567
+ S + S + SG Y N G ++ + L + +P P
Sbjct: 4620 TLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIP---PS 4676
Query: 568 LTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSS----APSGGEASFNLS 623
T ++ + ++ G ++L C GS PI ++ +D + +S + A +S
Sbjct: 4677 FTKKLKKMDSIKGSFIDLEC-IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEIS 4735
Query: 624 -LTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA 682
L SG Y+C A N A H+ S + V P P++Q V +
Sbjct: 4736 QLEGTDSGTYTCSATN--KAGHN---QCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKAL 4790
Query: 683 LRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSL-----TTEHSGIYSCEADNGLEAQR 737
+ G++P+ ++ ++ L +A S + SL SG Y C+ N +
Sbjct: 4791 VGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTAT 4850
Query: 738 SEMVTLKVAVPVS-----RPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHE--D 790
S+ TL V P PVL LR G C+ + G+P I ++ + +
Sbjct: 4851 SK-ATLFVKEPPQFIKKPSPVLVLRN-------GQSTTFECQ-ITGTPKIRVSWYLDGNE 4901
Query: 791 VTLGNRSSPS---GGASLNLS-LTAEHSGNYSCEADNGLG 826
+T + S G A+ +S E+SG Y CEA N G
Sbjct: 4902 ITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 4941
Score = 49.3 bits (116), Expect = 2e-05
Identities = 127/620 (20%), Positives = 211/620 (34%), Gaps = 130/620 (20%)
Query: 300 EGTKVTLHCETQEDSLRTLYRFYHEGVPL------RHKSVRCERGASISFSLTTENSGNY 353
E + + E ED + +Y +G+ + RHK V R + S T ++
Sbjct: 3160 EKQRAVVEFEVNEDDVDA--HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGE 3217
Query: 354 YCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL----------IFEGA---KVTLH 400
Y + + +V+L V P VL P + + G K++ +
Sbjct: 3218 YTF----VAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3273
Query: 401 CEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSK 460
E Q S +F H+G + E + Y C A N +G +
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEY----------TLLLIEAFPEDAAVYTCEAKNDYGVATTS 3323
Query: 461 AVSLSVTVP----------VSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHE 510
A SLSV VP V P + + +T EG C V + +Y +
Sbjct: 3324 A-SLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVS--GTDLKVSWYSK 3380
Query: 511 DMPLWSSSTPSVGRVSFSFSLTEGHS-----GNYYCTADNGFGPQRSEVVSLFVTVPVS- 564
D + S + + ++ L + G Y A N G Q S +L + P S
Sbjct: 3381 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG-QVSSTANLSLEAPESI 3439
Query: 565 ---------------RPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWF------YHE 603
P++ ++ + +G L + CE WF Y
Sbjct: 3440 LHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYES 3499
Query: 604 D-VTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILT 662
D ++ SS S E L G Y+C+A+N S T +L+V P
Sbjct: 3500 DKCSIRSSKYISSLEI---LRTQVVDCGEYTCKASNEY-GSVSCTATLTV-TEAYPPTFL 3554
Query: 663 FRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNL------- 715
R VG + C +P++ + +D G +PS +
Sbjct: 3555 SRPKSLTTFVGKAAKFICTVT--GTPVIETIWQKD---GAALSPSPNWRISDAENKHILE 3609
Query: 716 --SLTTEHSGIYSCEADN--GLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLEL 771
+LT + G+YSC+A N G + ++E++ + +P +A+ + L
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELII------IDKPHFIKELEPVQSAINKKVHL 3663
Query: 772 HCEALRGSPLIL--------------YRFFHEDVTLGNRSSPSGGASLNLSLT-AEHSGN 816
C+ + + Y+ ED A+L + L + SG
Sbjct: 3664 ECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKI----------ATLEIPLAKLKDSGT 3713
Query: 817 YSCEADNGLGAQR-SETVTL 835
Y C A N G+ S TVT+
Sbjct: 3714 YVCTASNEAGSSSCSATVTV 3733
Score = 44.7 bits (104), Expect = 4e-04
Identities = 96/455 (21%), Positives = 162/455 (35%), Gaps = 62/455 (13%)
Query: 73 NILEVQESGEYRCQAQGS--PLSSPVHLDFSSASLILQAPLSVFE-----GDSVVLRCRA 125
N +++ +SGEY C+A+ S +S+ L L + + G VV C
Sbjct: 8021 NQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAI 8080
Query: 126 KAEVTLNNTIYKNDNVL--------AFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPV- 176
++ + YK+ L +FL+ +I G Y CT P+
Sbjct: 8081 SGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATN----PIG 8136
Query: 177 -SSNTVKIQVQEPFTRPV--LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQ 233
+S++ ++ + E P +R + + G C P++ + +D +
Sbjct: 8137 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHV-----TGTQPIKVSWAKDSR 8191
Query: 234 TLGLGWSL-------SPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASH 286
+ G S + + + DSG Y C A V DS + + ++
Sbjct: 8192 EIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVN---EVGKDSCTAQLNIKERLIP 8248
Query: 287 PVLTLS-PEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSL 345
P T E EG L T+ +Y + ++ S CE I+F
Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITV-AWYKNNIEIQPTS-NCE----ITFKN 8302
Query: 346 TT----------ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGA 395
T ++G Y C N G+ + S+ + P PV + + EG
Sbjct: 8303 NTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTS-SIVIKEPKKPPVFDQHLTPVTVSEGE 8361
Query: 396 KVTLHCEAQRGSLPILYQFHHEGAAL---ERRSANSAGGVAI--SFSLTAEHSGNYYCTA 450
V L C Q GS PI Q+ G + +R S + A G A+ + SG+Y C A
Sbjct: 8362 YVQLSCHVQ-GSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKA 8420
Query: 451 DNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTF 485
N G +K+ P P ++ + F
Sbjct: 8421 SNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLF 8455
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/167 (23%), Positives = 70/167 (41%), Gaps = 15/167 (8%)
Query: 672 VGDLLELHCEALRGSSPILYWF-YHEDVTLGKISAPSGGGASFNLSLTTEHS---GIYSC 727
+G+ +L C+ + P + W+ + +++ + S G + L++ TE G+Y+C
Sbjct: 30546 LGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 30605
Query: 728 EADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFF 787
A N + + L A P P L+ + AVG L LH + G P+ +F
Sbjct: 30606 IATNEVGEVETSSKLLLQATPQFHPGYPLKEK-YYGAVGSTLRLHVMYI-GRPVPAMTWF 30663
Query: 788 H--------EDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLG 826
H E++T+ N + N+ H+G Y + N G
Sbjct: 30664 HGQKLLQNSENITIENTEHYTHLVMKNVQ-RKTHAGKYKVQLSNVFG 30709
Score = 39.7 bits (91), Expect = 0.014
Identities = 49/193 (25%), Positives = 74/193 (38%), Gaps = 18/193 (9%)
Query: 473 PVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSF--- 529
P T + EG+T T + G P ++ + + +S+ P V ++SFS
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHIS-GFPVPEVSWFRDGQVISTSTLPGV-QISFSDGRA 63
Query: 530 -----SLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLE 584
++T+ +SG Y A NG G Q + L V + P R+ G +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSG-QATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122
Query: 585 LHCEAPRGSPPILYWFYHEDVTLGSS---SAPSGGEASFNLSLTA--EHSGNYSCEANNG 639
L G P + FY + + SS G+ L A E SG YS A N
Sbjct: 123 LQVRV-TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 640 LVAQHSDTISLSV 652
V + + T L V
Sbjct: 182 -VGRATSTAELLV 193
Score = 36.2 bits (82), Expect = 0.15
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 11/109 (10%)
Query: 462 VSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSS---- 517
V V +PV+ P L EG +VTL C + G P +Y ED + SS
Sbjct: 932 VPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQ 990
Query: 518 --STPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVS 564
+ R+ + E SG + C+A N G + S ++ V VS
Sbjct: 991 ITFQSGIARLMIREAFAE-DSGRFTCSAVNEAG---TVSTSCYLAVQVS 1035
Score = 33.5 bits (75), Expect = 1.00
Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 11/103 (10%)
Query: 559 VTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSS-----SAP 613
V +PV+ P L + + G+ + L C P + W Y ED + SS +
Sbjct: 936 VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTW-YREDYQIESSIDFQITFQ 994
Query: 614 SGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPV 656
SG AE SG ++C A N + T+S S + V
Sbjct: 995 SGIARLMIREAFAEDSGRFTCSAVN-----EAGTVSTSCYLAV 1032
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/116 (29%), Positives = 50/116 (43%), Gaps = 9/116 (7%)
Query: 439 TAEHSGNYYCTADNGFGPQRSKAVSLSVTV-PVSHPVLTLSSAEALTFEGATVTLHCEVQ 497
T + SG Y T N P KAV ++V V PV L ++ +T V+
Sbjct: 18669 TRDDSGKYSLTLVN---PAGEKAVFVNVRVLDTPGPVSDLKVSD-VTKTSCHVSWAPPEN 18724
Query: 498 RGSPQILYQFYHE---DMPLWSSSTPSVGRVSFSF-SLTEGHSGNYYCTADNGFGP 549
G Q+ + + D WS+ TP V + SF +L G+ + TA N +GP
Sbjct: 18725 DGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP 18780
Score = 32.3 bits (72), Expect = 2.2
Identities = 35/161 (21%), Positives = 63/161 (39%), Gaps = 19/161 (11%)
Query: 94 SPVHLDFSSASLILQAP-LSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVL--------AF 144
+PV + + +L+ ++V EG+SV L C + T Y+ D + F
Sbjct: 934 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 993
Query: 145 LNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISG 204
+ I A +D+G + C+ E+ +S + +QV E F + +
Sbjct: 994 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE------ 1047
Query: 205 NPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNF 245
T E + +E DV + ++Q G G +P F
Sbjct: 1048 ---KFTTEEKRFVESRDVVMTDTSLTEEQA-GPGEPAAPYF 1084
Score = 31.6 bits (70), Expect = 3.8
Identities = 37/139 (26%), Positives = 51/139 (36%), Gaps = 17/139 (12%)
Query: 338 GASISFS----------LTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSP 387
G ISFS +T NSG Y A NG G S A L V + P
Sbjct: 53 GVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTA-ELLVKAETAPPNFVQRLQ 111
Query: 388 EDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLT-----AEH 442
+ +G++V L P++ +F+ +GA ++ +SL E
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVV-KFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170
Query: 443 SGNYYCTADNGFGPQRSKA 461
SG Y A N G S A
Sbjct: 171 SGTYSVNATNSVGRATSTA 189
Score = 31.6 bits (70), Expect = 3.8
Identities = 27/119 (22%), Positives = 49/119 (41%), Gaps = 12/119 (10%)
Query: 99 DFSSASLILQAPLS--VFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRT------- 149
+ S A + P S + EG +V+ C E + +KN+ ++ + +
Sbjct: 33129 ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV 33188
Query: 150 -DFHIPHACLKDNGAY--RCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGN 205
I +A + D+G Y + ++ C +S V V+EP VLR S + G+
Sbjct: 33189 YSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGS 33247
Score = 30.4 bits (67), Expect = 8.5
Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 8/104 (7%)
Query: 635 EANNGLVAQHSDT--ISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW 692
E +G A+ ++T + V +PV+ P L + G+ + L C SP + W
Sbjct: 917 EVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTW 976
Query: 693 FYHEDVTLG-----KISAPSGGGASFNLSLTTEHSGIYSCEADN 731
Y ED + +I+ SG E SG ++C A N
Sbjct: 977 -YREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVN 1019
Score = 30.4 bits (67), Expect = 8.5
Identities = 64/295 (21%), Positives = 99/295 (33%), Gaps = 31/295 (10%)
Query: 283 PASHPVLTLSPE---------KALNFEGTKVTLHCETQE-DSLRTLYRF---YHEGVPLR 329
PAS PV+ P + L+ VTL E E D + + + Y +
Sbjct: 30417 PASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSA 30476
Query: 330 HKSVRCERGASISFSL-----TTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSH-PVLN 383
K ER F++ TE + + GL A+S+ + P +
Sbjct: 30477 WKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIR 30536
Query: 384 LSSPEDLIFEGAKVTLHCEAQRGSLPIL--YQFHHEGAALERRSANSAGGVAISFSLTAE 441
+ G L C+ LP + Y+F E + +S G +T E
Sbjct: 30537 KEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 30596
Query: 442 HS--GNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRG 499
G Y C A N G + + L P HP L + G+T+ LH + G
Sbjct: 30597 QEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKE-KYYGAVGSTLRLHV-MYIG 30654
Query: 500 SPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLT------EGHSGNYYCTADNGFG 548
P ++H L +S ++ L + H+G Y N FG
Sbjct: 30655 RPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG 30709
>gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isoform
3 [Homo sapiens]
Length = 291
Score = 112 bits (280), Expect = 2e-24
Identities = 73/198 (36%), Positives = 99/198 (50%), Gaps = 8/198 (4%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW +L LAPV+G A P+ ++ L+P W V Q + VTLTC+G +W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 87
Query: 61 YLGKEILRETPDNI---LEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAP-LSVFEG 116
G I T + +SGEY CQ + LS PVHL S L+LQ P L EG
Sbjct: 88 --GNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEG 145
Query: 117 DSVVLRCRA-KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCP 175
+++VLRC + K + + T ++N F +F IP A +G Y CTG
Sbjct: 146 ETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG-NIGYTL 204
Query: 176 VSSNTVKIQVQEPFTRPV 193
SS V I VQ P + P+
Sbjct: 205 YSSKPVTITVQAPSSSPM 222
Score = 49.7 bits (117), Expect = 1e-05
Identities = 46/194 (23%), Positives = 74/194 (38%), Gaps = 17/194 (8%)
Query: 283 PASHP--VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGAS 340
PA+ P VL L P+ + VTL C +++H G + S
Sbjct: 44 PAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNG-----NLIPTHTQPS 98
Query: 341 ISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLH 400
F +SG Y C + P LS + + P L EG + L
Sbjct: 99 YRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ-------EGETIVLR 151
Query: 401 CEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSK 460
C + + + F G + ++ + S +I HSG+Y+CT + G+ SK
Sbjct: 152 CHSWKDKPLVKVTFFQNGKS--KKFSRSDPNFSIP-QANHSHSGDYHCTGNIGYTLYSSK 208
Query: 461 AVSLSVTVPVSHPV 474
V+++V P S P+
Sbjct: 209 PVTITVQAPSSSPM 222
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/217 (23%), Positives = 83/217 (38%), Gaps = 23/217 (10%)
Query: 674 DLLELHCEALRG-SSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNG 732
D + L C S + WF++ ++ P+ S+ SG Y+C+
Sbjct: 65 DSVTLTCRGTHSPESDSIQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTG-- 116
Query: 733 LEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
+ S+ V L V L L+ P G+ + L C + + PL+ FF
Sbjct: 117 -QTSLSDPVHLTVL----SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN--- 168
Query: 793 LGNRSSPSGGASLNLSLTA---EHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFA 849
+S + N S+ HSG+Y C + G S+ VT+ + +++ G
Sbjct: 169 --GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMG-II 225
Query: 850 TGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPA 886
V G+ A +AA L+YC R + D A
Sbjct: 226 VAVVTGIAVAAIVAAVVALIYCRKKRISANPTNPDEA 262
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/190 (23%), Positives = 70/190 (36%), Gaps = 21/190 (11%)
Query: 381 VLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTA 440
VL L + + VTL C Q+ H G + + S F
Sbjct: 51 VLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANN 105
Query: 441 EHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGS 500
SG Y C ++S V + V L L + EG T+ L C +
Sbjct: 106 NDSGEYTCQTGQ-------TSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDK 158
Query: 501 PQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG---HSGNYYCTADNGFGPQRSEVVSL 557
P + F+ + + R +FS+ + HSG+Y+CT + G+ S+ V++
Sbjct: 159 PLVKVTFFQ------NGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTI 212
Query: 558 FVTVPVSRPI 567
V P S P+
Sbjct: 213 TVQAPSSSPM 222
Score = 44.3 bits (103), Expect = 6e-04
Identities = 39/174 (22%), Positives = 71/174 (40%), Gaps = 18/174 (10%)
Query: 597 LYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPV 656
+ WF++ ++ P+ + S+ SG Y+C+ + SD + L+V+
Sbjct: 82 IQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTGQTSL---SDPVHLTVL--- 129
Query: 657 SRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLS 716
L + P + G+ + L C + + + F+ GK S +F++
Sbjct: 130 -SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN----GKSKKFSRSDPNFSIP 184
Query: 717 LTTE-HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLL 769
HSG Y C + G S+ VT+ V P S P+ + A T AV ++
Sbjct: 185 QANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIV 238
>gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isoform
1 [Homo sapiens]
Length = 310
Score = 112 bits (280), Expect = 2e-24
Identities = 73/198 (36%), Positives = 99/198 (50%), Gaps = 8/198 (4%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW +L LAPV+G A P+ ++ L+P W V Q + VTLTC+G +W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 87
Query: 61 YLGKEILRETPDNI---LEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAP-LSVFEG 116
G I T + +SGEY CQ + LS PVHL S L+LQ P L EG
Sbjct: 88 --GNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEG 145
Query: 117 DSVVLRCRA-KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCP 175
+++VLRC + K + + T ++N F +F IP A +G Y CTG
Sbjct: 146 ETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG-NIGYTL 204
Query: 176 VSSNTVKIQVQEPFTRPV 193
SS V I VQ P + P+
Sbjct: 205 YSSKPVTITVQAPSSSPM 222
Score = 49.7 bits (117), Expect = 1e-05
Identities = 46/194 (23%), Positives = 74/194 (38%), Gaps = 17/194 (8%)
Query: 283 PASHP--VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGAS 340
PA+ P VL L P+ + VTL C +++H G + S
Sbjct: 44 PAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNG-----NLIPTHTQPS 98
Query: 341 ISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLH 400
F +SG Y C + P LS + + P L EG + L
Sbjct: 99 YRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ-------EGETIVLR 151
Query: 401 CEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSK 460
C + + + F G + ++ + S +I HSG+Y+CT + G+ SK
Sbjct: 152 CHSWKDKPLVKVTFFQNGKS--KKFSRSDPNFSIP-QANHSHSGDYHCTGNIGYTLYSSK 208
Query: 461 AVSLSVTVPVSHPV 474
V+++V P S P+
Sbjct: 209 PVTITVQAPSSSPM 222
Score = 48.1 bits (113), Expect = 4e-05
Identities = 47/202 (23%), Positives = 79/202 (39%), Gaps = 23/202 (11%)
Query: 674 DLLELHCEALRG-SSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNG 732
D + L C S + WF++ ++ P+ S+ SG Y+C+
Sbjct: 65 DSVTLTCRGTHSPESDSIQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTG-- 116
Query: 733 LEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
+ S+ V L V L L+ P G+ + L C + + PL+ FF
Sbjct: 117 -QTSLSDPVHLTVL----SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN--- 168
Query: 793 LGNRSSPSGGASLNLSLTA---EHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFA 849
+S + N S+ HSG+Y C + G S+ VT+ + +++ G
Sbjct: 169 --GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMG-II 225
Query: 850 TGVAGGLLSIAGLAAGALLLYC 871
V G+ A +AA L+YC
Sbjct: 226 VAVVTGIAVAAIVAAVVALIYC 247
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/190 (23%), Positives = 70/190 (36%), Gaps = 21/190 (11%)
Query: 381 VLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTA 440
VL L + + VTL C Q+ H G + + S F
Sbjct: 51 VLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANN 105
Query: 441 EHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGS 500
SG Y C ++S V + V L L + EG T+ L C +
Sbjct: 106 NDSGEYTCQTGQ-------TSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDK 158
Query: 501 PQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG---HSGNYYCTADNGFGPQRSEVVSL 557
P + F+ + + R +FS+ + HSG+Y+CT + G+ S+ V++
Sbjct: 159 PLVKVTFFQ------NGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTI 212
Query: 558 FVTVPVSRPI 567
V P S P+
Sbjct: 213 TVQAPSSSPM 222
Score = 44.7 bits (104), Expect = 4e-04
Identities = 43/191 (22%), Positives = 77/191 (40%), Gaps = 23/191 (12%)
Query: 597 LYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPV 656
+ WF++ ++ P+ + S+ SG Y+C+ + SD + L+V+
Sbjct: 82 IQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTGQTSL---SDPVHLTVL--- 129
Query: 657 SRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLS 716
L + P + G+ + L C + + + F+ GK S +F++
Sbjct: 130 -SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN----GKSKKFSRSDPNFSIP 184
Query: 717 LTTE-HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLE----- 770
HSG Y C + G S+ VT+ V P S P+ + A T AV ++
Sbjct: 185 QANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIVAAVVAL 244
Query: 771 LHCEALRGSPL 781
++C R S L
Sbjct: 245 IYCRKKRISAL 255
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 112 bits (279), Expect = 2e-24
Identities = 205/866 (23%), Positives = 337/866 (38%), Gaps = 99/866 (11%)
Query: 21 PRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYH-----RYLGKEILRETPDNIL 75
P P+I + P TV GER LTC T W R +R + L
Sbjct: 519 PPPVIQV-PNNVTVTPGERAVLTCLIISAVDYNLT-WQRNDRDVRLAEPARIRTLANLSL 576
Query: 76 EVQ-----ESGEYRCQ--AQGSPLSSPVHLDFSSASLILQAPL--SVFEGDSVVLRCRA- 125
E++ ++GEY C ++G ++ V L + P S G V + C A
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 126 -----KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNT 180
K T+N+ + + T F I +A KD G Y C + ++T
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNST 695
Query: 181 VKIQVQEPFTRPVLRASSFQPISGNPVTLTCET------QLSLERSDVPLR-FRFFRDDQ 233
++ ++ P + ++ S G+ + C+T Q+ + D+ LR F D
Sbjct: 696 LRY-IEAP--KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDP 752
Query: 234 TLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSP 293
LGL +I D+G Y C A I+++ R+ ++ + P + +
Sbjct: 753 LLGL-------LKIQETQDLDAGDYTCVA-------INEAGRATGKITLDVGSPPVFIQE 798
Query: 294 EKALNFE-GTKVTLHCETQEDSLRTLYRFYHEGVPL--RHKSV----RCERGASISFSLT 346
++ E G+ VTL C Q T+ + +P+ R SV + GA +L
Sbjct: 799 PADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW 858
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRG 406
+ G Y C A+N G K +++VT V+ P++ +S + EG ++TL C G
Sbjct: 859 ASDKGTYICEAENQFG-KIQSETTVTVTGLVA-PLIGISPSVANVIEGQQLTLPCTLLAG 916
Query: 407 S-LPILYQFHHEGAALERR--SANSAGGVAISFSLTAEHSGNYYCTADNGFGP-QRSKAV 462
+ +P + L+ + S G + I + + G Y C A N G ++ +V
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIE-RVQLQDGGEYTCVASNVAGTNNKTTSV 975
Query: 463 SLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSV 522
+ V + H LS T EG VTL C+ + ++ SS+ S
Sbjct: 976 VVHVLPTIQHGQQILS-----TIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA 1030
Query: 523 GRVSFSFSLTEG--HSGNYYCTADNGFGPQRSEV-VSLFVTVPV---SRPILTLRVPRAQ 576
G + ++ G SG Y CTA N G + +V ++++V V R + +
Sbjct: 1031 GADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEIS 1090
Query: 577 AVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAP-----SGGEASFNLSLTAEHSGN 631
+ G+ + L CE PPI+ W ++ L S +P G + T++ SG
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITW--AKETQLISPFSPRHTFLPSGSMKITETRTSD-SGM 1147
Query: 632 YSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILY 691
Y C A N + + + L+V VP P + + VG +++ C A P++
Sbjct: 1148 YLCVATN-IAGNVTQAVKLNVHVP---PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVIT 1203
Query: 692 WFYHEDVTL--GKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPV 749
W L G+ + G T +GIY+C A N +E +TL V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETE-ITLHVQEPP 1262
Query: 750 SRPVLTLRAPGT----HAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS-----PS 800
+ V L P +E C A +G+P ++ H L R
Sbjct: 1263 T--VEDLEPPYNTTFQERVANQRIEFPCPA-KGTPKPTIKWLHNGRELTGREPGISILED 1319
Query: 801 GGASLNLSLTAEHSGNYSCEADNGLG 826
G + S+T +G Y C A N G
Sbjct: 1320 GTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 102 bits (253), Expect = 2e-21
Identities = 188/815 (23%), Positives = 316/815 (38%), Gaps = 101/815 (12%)
Query: 77 VQESGEYRCQAQGSPLS--SPVHLDFSSASLILQAP--LSVFEGDSVVLRCRAKAEVTLN 132
+ + G Y C A S + + D S ++Q P ++V G+ VL C + V N
Sbjct: 491 LSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550
Query: 133 NTIYKNDNVLAFLNK-------RTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQV 185
T +ND + + D G Y C E +S V + V
Sbjct: 551 LTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAAS--VFLTV 608
Query: 186 QEPFTRPVL-RASSFQPISGNPVTLTCET------QLSLERSDVPL----RFRFFRDDQT 234
QEP V+ + SF G+ V++ C +++ +D+ + R+R D
Sbjct: 609 QEPPKVTVMPKNQSFT--GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL 666
Query: 235 LGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPE 294
I KD+G Y C A+ + +S +I+ P L +
Sbjct: 667 F-----------IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEA------PKLMVVQS 709
Query: 295 KALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKS---VRCERGASISFSLTTENSG 351
+ L G + C+T + +++ + LR + + G ++G
Sbjct: 710 ELLVALGDITVMECKTSGIPPPQV-KWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAG 768
Query: 352 NYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFE-GAKVTLHCEAQRGSLPI 410
+Y C A N G K +T+ V P + + P D+ E G+ VTL C Q P
Sbjct: 769 DYTCVAINEAGRATGK-----ITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPT 823
Query: 411 LYQFHHEGAALERRSANSAG------GVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSL 464
+ + + R + + G +L A G Y C A+N FG +S+ ++
Sbjct: 824 IKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSE-TTV 882
Query: 465 SVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSS---STPS 521
+VT V+ P++ +S + A EG +TL C + G+P ++ L + + S
Sbjct: 883 TVTGLVA-PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS 941
Query: 522 VGRVSFS-FSLTEGHSGNYYCTADNGFGPQR---SEVVSLFVTVPVSRPILTLRVPRAQA 577
G + L +G G Y C A N G S VV + T+ + IL+
Sbjct: 942 DGSLHIERVQLQDG--GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS-------T 992
Query: 578 VVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGE--ASFNLSLTAEHSGNYSCE 635
+ G + L C+A P + W ++ SS+ S G + + +S E SG Y C
Sbjct: 993 IEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCT 1052
Query: 636 ANNGLVAQHSDTISLSVIVPV-----SRPILTFRAPRAQAVVGDLLELHCEALRGSSPIL 690
A N + L+V V R + + + G+ + L CE PI+
Sbjct: 1053 ATN-TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPII 1111
Query: 691 YWFYHEDVTLGKISAPSGGGASFNLSLT---TEHSGIYSCEADNGLEAQRSEMVTLKVAV 747
W E + S S ++ +T T SG+Y C A N + ++ V L V V
Sbjct: 1112 TW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN-IAGNVTQAVKLNVHV 1169
Query: 748 PVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTL-----GNRSSPSGG 802
P P + VG +++ C A +G+PL + + T+ + S+P G
Sbjct: 1170 P---PKIQRGPKHLKVQVGQRVDIPCNA-QGTPLPVITWSKGGSTMLVDGEHHVSNPDGT 1225
Query: 803 ASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYI 837
S++ T +G Y+C A N G +E +TL++
Sbjct: 1226 LSID-QATPSDAGIYTCVATNIAGTDETE-ITLHV 1258
Score = 99.0 bits (245), Expect = 2e-20
Identities = 209/867 (24%), Positives = 325/867 (37%), Gaps = 116/867 (13%)
Query: 28 QPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPD------------NIL 75
+P TV + +VTL CK P T W E L+ TP N
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVIT-WLRN---GERLQATPRVRILSGGRYLQINNA 3682
Query: 76 EVQESGEYRCQAQGSP----------LSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA 125
++ ++ Y C A ++ P ++ SL+ + S VL C A
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLV------ILLNKSTVLECIA 3736
Query: 126 KAEVTLNNTIYKNDNVLAFLNKRTDF------HIPHACLKDNGAYRCTGYKESCCPVSSN 179
+ T T K+ VLA + R HI A + D G Y C +
Sbjct: 3737 EGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMA--TNAAGTDRR 3794
Query: 180 TVKIQVQEPFTRPVLRASSFQPISGN-PVTLTCETQLSLERSDVPLRFRFFR-------- 230
+ +QV P S P N V + +T L+ E + +P +R
Sbjct: 3795 RIDLQVHVP--------PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNV 3846
Query: 231 DDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLT 290
D S + I + D+ Y C T+ D + VQ+P P +
Sbjct: 3847 DQNQNSYRLLSSGSLVIISPSVDDTATYEC---TVTNGAGDDKRTVDLTVQVP---PSIA 3900
Query: 291 LSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL--RHKSVRCERGASISFSLTTE 348
P L + + C +++ + G+ L R R +I T
Sbjct: 3901 DEPTDFLVTKHAPAVITCTASGVPFPSIH-WTKNGIRLLPRGDGYRILSSGAIEILATQL 3959
Query: 349 N-SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGS 407
N +G Y C A N G+ + V+L V P PV+ E + + L CEA
Sbjct: 3960 NHAGRYTCVARNAAGSA-HRHVTLHVHEP---PVIQPQPSELHVILNNPILLPCEATGTP 4015
Query: 408 LPILYQFHHEGAALERRSANSA----GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVS 463
P + + EG + N A GG+ IS ++ E +G Y C A N G K +
Sbjct: 4016 SPFI-TWQKEGINVNTSGRNHAVLPSGGLQISRAVR-EDAGTYMCVAQNPAGTALGK-IK 4072
Query: 464 LSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSV- 522
L+V VP PV++ E + +TL CE G P ++ + + S V
Sbjct: 4073 LNVQVP---PVISPHLKEYVIAVDKPITLSCEAD-GLPPPDITWHKDGRAIVESIRQRVL 4128
Query: 523 --GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVG 580
G + +F + G +G+Y C A N G S L V VP +R V
Sbjct: 4129 SSGSLQIAF-VQPGDAGHYTCMAANVAGSS-STSTKLTVHVPPR-----IRSTEGHYTVN 4181
Query: 581 DLLE--LHCEAPRGSPPILYWFYHEDVT---LGSSSAPSGGEASFNLSLTAEHSGNYSCE 635
+ + L C A P + W + LG +A GE ++ E SG Y+C
Sbjct: 4182 ENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE-NVVLEDSGFYTCV 4240
Query: 636 ANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYH 695
ANN + + T+SL+V V P T G+ L L C+A P L W ++
Sbjct: 4241 ANNA-AGEDTHTVSLTVHV---LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 696 EDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSR---P 752
++ + +G ++ E SG Y C A+N + ++ PV + P
Sbjct: 4297 NNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP 4356
Query: 753 VLTLRAPGTHAAVGDLLELHCEALRG--SPLILYRFFHEDVTLGNRSSPSGGASLNLSLT 810
+ G +A L+CE ++G +P I + D+ + +R G SL + T
Sbjct: 4357 SNWIEPLGGNAI------LNCE-VKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGT 4409
Query: 811 A-EHSGNYSCEADNGLG-AQRSETVTL 835
E +G+Y+C A N G +RS ++TL
Sbjct: 4410 VNEDAGDYTCVATNEAGVVERSMSLTL 4436
Score = 84.7 bits (208), Expect = 4e-16
Identities = 190/869 (21%), Positives = 329/869 (37%), Gaps = 104/869 (11%)
Query: 23 PIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR---YLGKEILRETPDNIL---- 75
P+I + P V +G+++TL C + +W L + D L
Sbjct: 890 PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIER 949
Query: 76 -EVQESGEYRCQAQGSPLSSPVHLDFSSASLIL---------QAPLSVFEGDSVVLRCRA 125
++Q+ GEY C A S+ + + S+++ Q LS EG V L C+A
Sbjct: 950 VQLQDGGEYTCVA-----SNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKA 1004
Query: 126 KAEVTLNNTIYKNDNVLAFLNKR------TDFHIPHACLKDNGAYRCTGYKESCCPVSSN 179
+ K +++ + + ++ +++G Y CT +
Sbjct: 1005 SGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV 1064
Query: 180 TVKIQVQEPFTRPVLRASSFQPI-----SGNPVTLTCETQLSLERSDVPLRFRFFRDDQT 234
+ + V+ S +P+ +G VTL CE +S P + ++ Q
Sbjct: 1065 QLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEV-----KSLPPPIITWAKETQL 1119
Query: 235 LG-----LGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVL 289
+ + S + +IT + DSG Y C A + +V + + V +P P +
Sbjct: 1120 ISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV---TQAVKLNVHVP---PKI 1173
Query: 290 TLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEG-----VPLRHKSVRCERGASISFS 344
P+ G +V + C Q L + + +G V H + SI
Sbjct: 1174 QRGPKHLKVQVGQRVDIPCNAQGTPLPVI--TWSKGGSTMLVDGEHHVSNPDGTLSID-Q 1230
Query: 345 LTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFE----GAKVTLH 400
T ++G Y C A N G ++ ++L V P + V +L P + F+ ++
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETE-ITLHVQEPPT--VEDLEPPYNTTFQERVANQRIEFP 1287
Query: 401 CEAQRGSLPILYQFHHEGAALERR----SANSAGGVAISFSLTAEHSGNYYCTADNGFGP 456
C A+ P + ++ H G L R S G + + S+T +G Y C A N G
Sbjct: 1288 CPAKGTPKPTI-KWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGT 1346
Query: 457 QRSKAVSLSVTVPVSHPVLTLSSAEALT----FEGATVTLHCEVQRGSPQILYQFYHEDM 512
K +L V VP PV + E +T L CEV+ G+P + +Y +++
Sbjct: 1347 TERK-YNLKVHVP---PV--IKDKEQVTNVSVLLNQLTNLFCEVE-GTPSPIIMWYKDNV 1399
Query: 513 PLWSSSTPSV---GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILT 569
+ SST G++ F T +G Y C A N G + + ++ V VP + I+
Sbjct: 1400 QVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQ-KYFNIDVLVPPT--IIG 1456
Query: 570 LRVPRAQAVVGDL-LELHCEAPRGSP-PILYWFYH-EDVTLGSSSAP--SGGEASFNLSL 624
P +VV + + L C+ +G+P P ++WF + + LG + G+ +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQV-KGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNA 1515
Query: 625 TAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALR 684
G Y C +N Q D I L++ +P S ++ L++L CE
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKD-IKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRG 1573
Query: 685 GSSPILYWFYHEDVTLGKISA--PSGGGASFNLSLTTEHSGIYSCEADN-GLEAQRSEMV 741
P + W+ + A G S Y+C N A++S V
Sbjct: 1574 LPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHV 1633
Query: 742 TLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTL---GNRSS 798
+ V + + T + L L C+A G+P + + + V + N
Sbjct: 1634 DVYVPPMIEGNLAT--PLNKQVVIAHSLTLECKA-AGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 799 PSGGASLNLSLTAE-HSGNYSCEADNGLG 826
+GG L + E G Y C A + G
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Score = 83.2 bits (204), Expect = 1e-15
Identities = 182/818 (22%), Positives = 301/818 (36%), Gaps = 95/818 (11%)
Query: 78 QESGEYRCQAQGSP------------LSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA 125
+ESGEY C A + + V D S +SV G+ V L C
Sbjct: 1044 EESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEV 1103
Query: 126 KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLK-------DNGAYRCTGYKESCCPVSS 178
K+ T K +++ + R F +P +K D+G Y C + +
Sbjct: 1104 KSLPPPIITWAKETQLISPFSPRHTF-LPSGSMKITETRTSDSGMYLCVA--TNIAGNVT 1160
Query: 179 NTVKIQVQEPFTRPVLRASSFQPIS-GNPVTLTCETQLSLERSDVPLRFRFFRDDQTL-- 235
VK+ V P + R + G V + C Q + +P+ + + T+
Sbjct: 1161 QAVKLNVHVP--PKIQRGPKHLKVQVGQRVDIPCNAQ----GTPLPV-ITWSKGGSTMLV 1213
Query: 236 -GLGWSLSPN--FQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLS 292
G +P+ I D+G Y C A + + D + VQ P + V L
Sbjct: 1214 DGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGT---DETEITLHVQEPPT--VEDLE 1268
Query: 293 PEKALNFE----GTKVTLHCETQEDSLRTLYRFYHEGVPLRHK----SVRCERGASISFS 344
P F+ ++ C + T+ ++ H G L + S+ + + S
Sbjct: 1269 PPYNTTFQERVANQRIEFPCPAKGTPKPTI-KWLHNGRELTGREPGISILEDGTLLVIAS 1327
Query: 345 LTTENSGNYYCTADNGLGAKPSKAVSLSVTVPV----SHPVLNLSSPEDLIFEGAKVTLH 400
+T ++G Y C A N G K +L V VP V N+S + L
Sbjct: 1328 VTPYDNGEYICVAVNEAGTTERK-YNLKVHVPPVIKDKEQVTNVS-----VLLNQLTNLF 1381
Query: 401 CEAQRGSLPILYQFHHEGAALERRSANSA--GGVAISFSLTAEHSGNYYCTADNGFGPQR 458
CE + PI+ + E + + G + F T E +G Y C A N G +
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441
Query: 459 SKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSS 518
K ++ V VP + + T E V L C+V +G+P ++ + PL+
Sbjct: 1442 -KYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVALECQV-KGTPFPDIHWFKDGKPLFLGD 1498
Query: 519 TPSV-----GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEV-VSLFVTVPVSRPILTLRV 572
P+V G+V + G Y CT N G Q ++ +++++ + +T +
Sbjct: 1499 -PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDI 1557
Query: 573 PRAQAVVGDLLELHCEAPRGSP-PILYWFYHEDVTLGSSSAP--SGGEASFNLSLTAEHS 629
++ L++L CE RG P P + W+ + SS A G+ S
Sbjct: 1558 ---SVLINSLIKLECET-RGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDS 1613
Query: 630 GNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPI 689
Y+C N + + + V VP Q V+ L L C+A SPI
Sbjct: 1614 ATYTCHVAN-VAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPI 1672
Query: 690 LYWFYHEDVTL---GKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVA 746
L W + V + I +GG +S G Y C A + ++ + V
Sbjct: 1673 LTWL-KDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVA-TSVAGEKEIKYEVDVL 1730
Query: 747 VPVSRPVLTLRAPGTH--AAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS----PS 800
VP P + ++ V +LLEL C + GSP + + + R +
Sbjct: 1731 VP---PAIEGGDETSYFIVMVNNLLELDCH-VTGSPPPTIMWLKDGQLIDERDGFKILLN 1786
Query: 801 GGASLNLSLTAEHSGNYSCEADNGLGAQRSE-TVTLYI 837
G + ++G Y C A N G + E VT+++
Sbjct: 1787 GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV 1824
Score = 79.0 bits (193), Expect = 2e-14
Identities = 168/822 (20%), Positives = 306/822 (37%), Gaps = 94/822 (11%)
Query: 65 EILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAP----------LSVF 114
++ R TP+ ++G Y C+A +S + + +L P +SV
Sbjct: 1417 KLFRATPE------DAGRYSCKAINIAGTSQKYFNID----VLVPPTIIGTNFPNEVSVV 1466
Query: 115 EGDSVVLRCRAKAEVTLN-------NTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCT 167
V L C+ K + ++ D + L++ H+ +A D G Y+CT
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCT 1526
Query: 168 GYKESCCPVSSNTVKIQVQEPFTRPVLRASS----FQPISGNPVTLTCETQLSLERSDVP 223
+ + +K+ + P P ++ + + + + L CET+ +P
Sbjct: 1527 --VSNAAGKQAKDIKLTIYIP---PSIKGGNVTTDISVLINSLIKLECETR------GLP 1575
Query: 224 L-RFRFFRDDQTL-----GLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSW 277
+ +++D Q + L I DS Y C A +V + +S+
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVA----NVAGTAEKSF 1631
Query: 278 -IQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLR-HKSVRC 335
+ V +P +P +TL C+ + L + +GVP++ + ++R
Sbjct: 1632 HVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL-TWLKDGVPVKANDNIRI 1690
Query: 336 ERGASISFSLTTE--NSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPED--LI 391
E G ++ + + G Y C A + G K K + V VP P + ++
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIK-YEVDVLVP---PAIEGGDETSYFIV 1746
Query: 392 FEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSA---GGVAISFSLTAEHSGNYYC 448
+ L C GS P + +G ++ R G + ++G Y C
Sbjct: 1747 MVNNLLELDCHVT-GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRC 1805
Query: 449 TADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFY 508
A N G + + VTV V + + +E + + V L C + G P +
Sbjct: 1806 MAANTAGDHKKE---FEVTVHVPPTIKSSGLSERVVVKYKPVALQC-IANGIPNPSITWL 1861
Query: 509 HEDMPLWSSS----TPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVS 564
+D P+ ++ S GRV +G Y C A N G + + + L V P S
Sbjct: 1862 KDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAG-ETQQHIQLHVHEPPS 1920
Query: 565 RPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAP--SGGEASFNL 622
++ +V + ++L C+A P++ W+ + GS+S + G+
Sbjct: 1921 LEDAG-KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIE 1979
Query: 623 SLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA 682
S +G Y C A N A + S+ V V+ P ++ VV + + L CEA
Sbjct: 1980 SAQISDAGIYKCVAINSAGATE---LFYSLQVHVA-PSISGSNNMVAVVVNNPVRLECEA 2035
Query: 683 LRGSSPILYWFYHEDVT---LGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSE 739
+P L W + SGG S +G Y+C A N ++
Sbjct: 2036 RGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA-AGEKQR 2094
Query: 740 MVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHC--EALRGSPLILYRFFHEDVTLGNRS 797
+ L+V VP P + + +EL C +A+ L + H + S
Sbjct: 2095 DIDLRVYVP---PNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLS 2151
Query: 798 SPSGGASLNL-SLTAEHSGNYSCEADNGLG-AQRSETVTLYI 837
+ L + + +G Y+CEA N G +++ V +++
Sbjct: 2152 ISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWV 2193
Score = 78.6 bits (192), Expect = 3e-14
Identities = 144/643 (22%), Positives = 240/643 (37%), Gaps = 56/643 (8%)
Query: 222 VPLRFRFFRDDQTLG----LGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSW 277
+P F R+ TLG L S S N I + D GFY C A + S + +++
Sbjct: 457 LPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVS---SAGTGRAQTF 513
Query: 278 IQVQIPASHPVLTLSPEKALNFEGTKVTLHC--ETQEDSLRTLYRFYHEGVPLRHKSVRC 335
V P P + P G + L C + D T R + +R
Sbjct: 514 FDVSEP---PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRT 570
Query: 336 ERGASISF-SLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEG 394
S+ S+ ++G Y+C + G + +V L+V P P + + G
Sbjct: 571 LANLSLELKSVKFNDAGEYHCMVSSE-GGSSAASVFLTVQEP---PKVTVMPKNQSFTGG 626
Query: 395 AKVTLHCEAQRGSLP-ILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNG 453
++V++ C A P I + + R ++ G + + +G Y C A N
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 454 FGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMP 513
G + S + P L + +E L G + C+ G P +++ D+
Sbjct: 687 AGTDKQN----STLRYIEAPKLMVVQSELLVALGDITVMECKTS-GIPPPQVKWFKGDLE 741
Query: 514 LWSSS----TPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILT 569
L S+ P +G + + +G+Y C A N G + +T+ V P +
Sbjct: 742 LRPSTFLIIDPLLGLLKIQ-ETQDLDAGDYTCVAINEAGRATGK-----ITLDVGSPPVF 795
Query: 570 LRVPRAQAV-VGDLLELHCEAPRGSPPILYW-------FYHEDVTLGSSSAPSGGEASFN 621
++ P ++ +G + L C P + W + ++ S S G A F
Sbjct: 796 IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG-ALFI 854
Query: 622 LSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCE 681
L+L A G Y CEA N S+T + + P++ A + G L L C
Sbjct: 855 LNLWASDKGTYICEAENQFGKIQSET--TVTVTGLVAPLIGISPSVANVIEGQQLTLPCT 912
Query: 682 ALRGSS-PILYWFYHEDVTLGK--ISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRS 738
L G+ P W + + L I+ S G + + G Y+C A N +
Sbjct: 913 LLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIE-RVQLQDGGEYTCVASN---VAGT 968
Query: 739 EMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEAL-RGSPLILYRFFHEDVTLGNRS 797
T V V V P + G + L C+A P +++ E ++ +
Sbjct: 969 NNKTTSVVVHV-LPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 798 SPSG--GASLNLSLTAEHSGNYSCEADNGLG-AQRSETVTLYI 837
+G G+ +S E SG Y C A N G A+R +T+Y+
Sbjct: 1028 FSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV 1070
Score = 76.6 bits (187), Expect = 1e-13
Identities = 179/784 (22%), Positives = 292/784 (37%), Gaps = 92/784 (11%)
Query: 113 VFEGDSVVLRCRAKAEVTLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRC 166
V G S+ L C + T K+ + L L++ + + + D G Y C
Sbjct: 2304 VTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVC 2363
Query: 167 TGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPL-R 225
+ + + + + N V+LTCE S +PL
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEA------SGIPLPS 2417
Query: 226 FRFFRDDQTLGLGWS---LSPNFQITAMWS--KDSGFYWCKAATMPYSVISDSPRSWIQV 280
+F+D + L S LS + M + +D+G Y C + + + V
Sbjct: 2418 ITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRN---AAGEERKIFGLSV 2474
Query: 281 QIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLR----HKSVRCE 336
+P H V + E E VTL CE + + + ++ +G PL+ H +
Sbjct: 2475 LVPP-HIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEI-TWHKDGQPLQEDEAHHIISGG 2532
Query: 337 RGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTV-PVSHPVLNLSSPEDL-IFEG 394
R I+ ++ ++G Y C A + G K S++ SL+V V P V + +PED+ +
Sbjct: 2533 RFLQIT-NVQVPHTGRYTCLASSPAGHK-SRSFSLNVFVSPTIAGVGSDGNPEDVTVILN 2590
Query: 395 AKVTLHCEAQRGSLPILYQFHHEGAALE--RRSANSAGGVAISF-SLTAEHSGNYYCTAD 451
+ +L CEA P + +G LE R GG + + +++G Y C A
Sbjct: 2591 SPTSLVCEAYSYP-PATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVAT 2649
Query: 452 NGFGPQRSKAVSLSVTVPVSHPVLT--------LSSAEALTFEGATVTLHCEVQRGSPQI 503
N G + K + V +P P++ LS E T+TL CE P
Sbjct: 2650 NEAG-EMIKHYEVKVYIP---PIINKGDLWGPGLSPKEVKIKVNNTLTLECEAY-AIPSA 2704
Query: 504 LYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGH---SGNYYCTADNGFGPQRSEVVSLFVT 560
+Y + PL S ++ + + E +G Y C A N G + + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDF-DVNIQ 2763
Query: 561 VPVSRPIL--------TLRVPRAQ-AVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSS 611
VP S L T R A+ ++ + + L+CE PP L W Y + L SS
Sbjct: 2764 VPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTW-YKDGHPLTSSD 2822
Query: 612 AP---SGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRA 668
GG E +G Y+C A N + S + V+VP P
Sbjct: 2823 KVLILPGGRVLQIPRAKVEDAGRYTCVAVNE-AGEDSLQYDVRVLVPPIIKGANSDLPEE 2881
Query: 669 QAVVG------DLLELHCEALRGS-----SPILYWFYHEDVTLGKISAPSGGGASFNLSL 717
V+ + L A R S P+L +H+ ++ G+I N +
Sbjct: 2882 VTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRIL------QILNTQI 2935
Query: 718 TTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALR 777
T G Y C A+N + L V VP S V+ ++ V + + L CE
Sbjct: 2936 T--DIGRYVCVAEN-TAGSAKKYFNLNVHVPPS--VIGPKSENLTVVVNNFISLTCEVSG 2990
Query: 778 GSPLILYRFFHEDVTLGNRSS---PSGGASLNLSLTAEHSGNYSCEADNGLGAQRSE-TV 833
P L +E N ++ P G + G Y+C A N G + + ++
Sbjct: 2991 FPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Query: 834 TLYI 837
T+Y+
Sbjct: 3051 TVYV 3054
Score = 75.1 bits (183), Expect = 3e-13
Identities = 157/707 (22%), Positives = 260/707 (36%), Gaps = 86/707 (12%)
Query: 202 ISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSL-----SPNFQITAMWSKDSG 256
I +P +L CE S P +F+D L ++ QI ++G
Sbjct: 2588 ILNSPTSLVCEAY-----SYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAG 2642
Query: 257 FYWCKAATMPYSVISDSPRSWIQVQIPASHPVLT--------LSPEKALNFEGTKVTLHC 308
Y C A +I ++V IP P++ LSP++ +TL C
Sbjct: 2643 RYSCVATNEAGEMIKHYE---VKVYIP---PIINKGDLWGPGLSPKEVKIKVNNTLTLEC 2696
Query: 309 ETQEDSLRTLYRFYHEGVPLR---HKSVRCERGASISFSLTTENSGNYYCTADNGLGAKP 365
E +L +Y +G PL+ H ++ ++G Y C A N + +
Sbjct: 2697 EAYAIPSASL-SWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASN-IAGED 2754
Query: 366 SKAVSLSVTVPVSHPVL----------NLSSPEDLIFEGAKVTLHCEAQRGSLPIL--YQ 413
+++ VP S L +D+I ++L+CE P L Y+
Sbjct: 2755 ELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNP-ISLYCETNAAPPPTLTWYK 2813
Query: 414 FHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHP 473
H + ++ G V E +G Y C A N G + S + V VP P
Sbjct: 2814 DGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG-EDSLQYDVRVLVP---P 2869
Query: 474 VLTLSSA----EALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTP---SVGRVS 526
++ +++ E + + C + GSP + + PL S GR+
Sbjct: 2870 IIKGANSDLPEEVTVLVNKSALIEC-LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRIL 2928
Query: 527 FSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELH 586
+ G Y C A+N G + + +L V VP S ++ + VV + + L
Sbjct: 2929 QILNTQITDIGRYVCVAENTAGSAK-KYFNLNVHVPPS--VIGPKSENLTVVVNNFISLT 2985
Query: 587 CEAPRGSPPILYWFYHED-VTLGSSS-APSGGEASFNLSLTAEHSGNYSCEANNGLVAQH 644
CE PP L W +E + L +++ GG + G Y+C A N +
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN-QAGES 3044
Query: 645 SDTISLSVIVPVSRPILTFRAPRAQAVV----GDLLELHCEALRGSSPILYWFYHEDVTL 700
SL+V VP P + + +VV G + L CE+ P++ W+ + +
Sbjct: 3045 KKKFSLTVYVP---PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101
Query: 701 GK--ISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRA 758
+ + G +G Y C A N + + + L V VP S +
Sbjct: 3102 ESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN-VAGRDDKNFHLNVYVPPS-----IEG 3155
Query: 759 PGTHAAVGDL---LELHCEALRGSPLILYRFFHEDVTLGNRSS-----PSGGASLNLSLT 810
P V + + L C+A G P + + N S SGG+ L ++ +
Sbjct: 3156 PEREVIVETISNPVTLTCDA-TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARS 3214
Query: 811 A-EHSGNYSCEADNGLG-AQRSETVTLYITGLTANRSGPFATGVAGG 855
SGNY+C A N G AQ+ +++ + A P V G
Sbjct: 3215 QHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLG 3261
Score = 73.9 bits (180), Expect = 7e-13
Identities = 148/589 (25%), Positives = 231/589 (39%), Gaps = 60/589 (10%)
Query: 40 VTLTCKGFRFYSPQKTKWYHRYL----GKEILRETPDNILEVQ--ESGEYRCQAQGSPLS 93
+T T G F S TK R L G IL IL Q +G Y C A+ + S
Sbjct: 3916 ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS 3975
Query: 94 SPVH--LDFSSASLILQAP--LSVFEGDSVVLRCRA----------KAEVTLNNTIYKND 139
+ H L +I P L V + ++L C A + E NT +N
Sbjct: 3976 AHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035
Query: 140 NVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSF 199
VL I A +D G Y C + + + +QV P P L+ +
Sbjct: 4036 AVLP----SGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVP-PVISPHLK--EY 4088
Query: 200 QPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYW 259
P+TL+CE L D+ +++ S + QI + D+G Y
Sbjct: 4089 VIAVDKPITLSCEAD-GLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYT 4147
Query: 260 CKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRT-L 318
C AA + S S + + V +P + + +N E ++ L C D + T
Sbjct: 4148 CMAANVAGS---SSTSTKLTVHVPPR--IRSTEGHYTVN-ENSQAILPCVA--DGIPTPA 4199
Query: 319 YRFYHEGVPLRH---KSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTV 375
+ + V L + K G I ++ E+SG Y C A+N G + + VSL+V V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG-EDTHTVSLTVHV 4258
Query: 376 PVSHPVLNLSSPEDL-IFEGAKVTLHCEAQRGSLPIL-YQFHHEGAALERRSANSAGGVA 433
+ L P D+ + +G ++ L C+A LP L + F++ S N +
Sbjct: 4259 LPTFTEL----PGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELV 4314
Query: 434 ISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLH 493
I ++ E SG Y CTA+N G ++ PV + E L G L+
Sbjct: 4315 IE-RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL---GGNAILN 4370
Query: 494 CEVQRGSPQILYQFYHEDMPLW-SSSTPSVGRVSFS-FSLTEGHSGNYYCTADNGFGP-Q 550
CEV +G P Q+ + + + S +G S + + +G+Y C A N G +
Sbjct: 4371 CEV-KGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 551 RSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYW 599
RS ++L S PI+TL G + L+C+A P + W
Sbjct: 4430 RSMSLTL-----QSPPIITLEPVETVINAGGKIILNCQATGEPQPTITW 4473
Score = 73.6 bits (179), Expect = 9e-13
Identities = 129/555 (23%), Positives = 223/555 (40%), Gaps = 64/555 (11%)
Query: 161 NGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRA--SSFQPISGNPVTLTCETQLSLE 218
N A R T + + V + V EP PV++ S I NP+ L CE
Sbjct: 3960 NHAGRYTCVARNAAGSAHRHVTLHVHEP---PVIQPQPSELHVILNNPILLPCEA----- 4011
Query: 219 RSDVPLRFRFFRDD----QTLGLGWSLSPN--FQITAMWSKDSGFYWCKAATMPYSVISD 272
+ P F ++ + T G ++ P+ QI+ +D+G Y C A + +
Sbjct: 4012 -TGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALG- 4069
Query: 273 SPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKS 332
+ + VQ+P PV++ ++ + +TL CE D L +H+ +S
Sbjct: 4070 --KIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEA--DGLPPPDITWHKDGRAIVES 4122
Query: 333 VRCERGASISFSLT---TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPED 389
+R +S S + ++G+Y C A N G+ S + L+V VP P + +
Sbjct: 4123 IRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVHVP---PRIRSTEGHY 4178
Query: 390 LIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAG-------GVAISFSLTAEH 442
+ E ++ L C A P + + + L AN G G I ++ E
Sbjct: 4179 TVNENSQAILPCVADGIPTPAI-NWKKDNVLL----ANLLGKYTAEPYGELILENVVLED 4233
Query: 443 SGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQR-GSP 501
SG Y C A+N G + + VSL+V V P T + +G + L C+ P
Sbjct: 4234 SGFYTCVANNAAG-EDTHTVSLTVHVL---PTFTELPGDVSLNKGEQLRLSCKATGIPLP 4289
Query: 502 QILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTV 561
++ + F + +P S + +++ SG Y CTA+N G ++ + ++V
Sbjct: 4290 KLTWTFNNNIIPAHFDSVNGHSELVIE-RVSKEDSGTYVCTAENSVGFVKA-IGFVYVKE 4347
Query: 562 PVSRPILTLRVPR--AQAVVGDLLELHCEAPRGSPPILYWFYHE-DVTLGSSSAPSGGEA 618
P P+ P + + G+ + L+CE P + W D+ + G +
Sbjct: 4348 P---PVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 619 SFNLSLTAEHSGNYSCEANNGL-VAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLE 677
E +G+Y+C A N V + S +++L S PI+T G +
Sbjct: 4404 LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ-----SPPIITLEPVETVINAGGKII 4458
Query: 678 LHCEALRGSSPILYW 692
L+C+A P + W
Sbjct: 4459 LNCQATGEPQPTITW 4473
Score = 64.7 bits (156), Expect = 4e-10
Identities = 185/817 (22%), Positives = 296/817 (36%), Gaps = 112/817 (13%)
Query: 76 EVQESGEYRCQAQGSPLSS-----------PVHLDFSSASLILQAPLSVFEGDSVVLRCR 124
+V + GEY C A S P D S SL + ++V EG SV L C
Sbjct: 3026 KVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSV---VNVREGTSVSLECE 3082
Query: 125 AKAEVTLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSS 178
+ A T YKN ++ L HI A + D G Y C + +
Sbjct: 3083 SNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKN 3142
Query: 179 NTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLG 238
+ + V P R + IS NPVTLTC+ P + ++ + +
Sbjct: 3143 FHLNVYVPPSIEGPE-REVIVETIS-NPVTLTCDA-----TGIPPPTIAWLKNHKRIENS 3195
Query: 239 WSL-------SPNFQITAMWSKDSGFYWCKAATMP------YSVISDSPRSWIQVQIPAS 285
SL QI DSG Y C A+ M Y + P S +IP+
Sbjct: 3196 DSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSD 3255
Query: 286 HPVLTLSPEKALNFEGTKVTLHCETQEDSLRT-LYRFYHEGVPLRHKSVRCER----GAS 340
VL G V L C + + T L ++ +G P+ R G++
Sbjct: 3256 VSVLL----------GENVELVCNA--NGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303
Query: 341 IS-FSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTL 399
++ + T ++G Y C A N G + + +L+V V + + + + + +
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAG-EEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 400 HCEAQRGSLPILYQFHHEGAALERRS---ANSAGGVAISFSLTAEHSGNYYCTADNGFGP 456
C A G+ P + G L S +AG V Y C A N G
Sbjct: 3363 ECRA-TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGV 3421
Query: 457 QRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWS 516
+K +L V P + ++ + E +G++ ++ C + G+P + + PL
Sbjct: 3422 D-NKHYNLQVFAPPNMD-NSMGTEEITVLKGSSTSMAC-ITDGTPAPSMAWLRDGQPLGL 3478
Query: 517 SSTPSVGRVSFSFSLTEGH---SGNYYCTADNGFGPQRSEVVSLFVTVPVSRPIL--TLR 571
+ +V L + SG Y C A N G EV F+ + P + +
Sbjct: 3479 DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG----EVSKHFILKVLEPPHINGSEE 3534
Query: 572 VPRAQAVVGDLLELHCEAPRGSPPILYWF--------YHEDVTLGSSSAPSGGEASFNLS 623
+V + LEL C A P + W + TLG GGE +
Sbjct: 3535 HEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG------GGEVLRIST 3588
Query: 624 LTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGD-LLELHCEA 682
E +G Y+C A++ D V V V I PR V+ + + L C++
Sbjct: 3589 AQVEDTGRYTCLASS---PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS 3645
Query: 683 LRGSSPILYWFYHED--VTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEM 740
P++ W + + ++ SGG + + Y+C A N + + +
Sbjct: 3646 DAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN-IAGKTTRE 3704
Query: 741 VTLKVAVPVS-----RPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGN 795
L V VP + + ++ L T +LE E + +P I +R V GN
Sbjct: 3705 FILTVNVPPNIKGGPQSLVILLNKST------VLECIAEGV-PTPRITWR-KDGAVLAGN 3756
Query: 796 RSSPSGGASLNLSLTAEH---SGNYSCEADNGLGAQR 829
+ S + L + + H +G Y C A N G R
Sbjct: 3757 HARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR 3793
Score = 60.1 bits (144), Expect = 1e-08
Identities = 120/508 (23%), Positives = 190/508 (37%), Gaps = 42/508 (8%)
Query: 344 SLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEA 403
S ++G Y C A N GA + S+ V V+ P ++ S+ + V L CEA
Sbjct: 1980 SAQISDAGIYKCVAINSAGATE---LFYSLQVHVA-PSISGSNNMVAVVVNNPVRLECEA 2035
Query: 404 QRGSLPILYQFHHEGAALERRSAN----SAGGVAISFSLTAEHSGNYYCTADNGFGPQRS 459
+ P L + +G+ + S S G + S +G Y C A N G ++
Sbjct: 2036 RGIPAPSL-TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG-EKQ 2093
Query: 460 KAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSST 519
+ + L V VP P + V L C+ P L + + PL
Sbjct: 2094 RDIDLRVYVP---PNIMGEEQNVSVLISQAVELLCQSDAIPPPTL-TWLKDGHPLLKKPG 2149
Query: 520 PSVGRVSFSFSLTEGH---SGNYYCTADNGFGP-QRSEVVSLFVTVPVSRPILTLRVPRA 575
S+ + + +G Y C A N G +++ V+++V + + + +
Sbjct: 2150 LSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGG---SDELTQL 2206
Query: 576 QAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAP----SGGEASFNLSLTAEHSGN 631
+ G+L+ L CE+ PP L W L S SGG +
Sbjct: 2207 TVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAAL 2266
Query: 632 YSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVV---GDLLELHCEALRGSSP 688
YSC A+N + +L V + RP +T ++ G + L CE P
Sbjct: 2267 YSCVASN-VAGTAKKEYNLQVYI---RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 689 ILYWFY--HEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVA 746
+ W H + + G ++ +G Y C A N + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVN-VAGMTDKKYDLSVH 2381
Query: 747 VPVSRPVLTLRAPGTHAAV-GDLLELHCEALRGSPLILYRFFHE--DVTLGNR-SSPSGG 802
P S + R+P + V + + L CEA G PL +F + V+L N SGG
Sbjct: 2382 APPS-IIGNHRSPENISVVEKNSVSLTCEA-SGIPLPSITWFKDGWPVSLSNSVRILSGG 2439
Query: 803 ASLNL-SLTAEHSGNYSCEADNGLGAQR 829
L L T E +G Y+C N G +R
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Score = 58.9 bits (141), Expect = 2e-08
Identities = 80/321 (24%), Positives = 131/321 (40%), Gaps = 31/321 (9%)
Query: 536 SGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPP 595
+G Y+C + G S S+F+TV P +T+ G + + C A P
Sbjct: 586 AGEYHCMVSSEGG---SSAASVFLTVQ-EPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 596 ILYWFYHEDVTLGSSSAPSGGEASFNLSLTA-EHSGNYSCEANNGLVAQHSDTISLSVIV 654
+ W ++ +GS + + + A + +G Y C A+N + S +
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQN----STLR 697
Query: 655 PVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGK----ISAPSGGG 710
+ P L +GD+ + C+ P + WF D+ L I P G
Sbjct: 698 YIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRPSTFLIIDPLLGL 756
Query: 711 ASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPG-THAAVGDLL 769
+ + +G Y+C A N EA R+ T K+ + V P + ++ P +G +
Sbjct: 757 LKIQETQDLD-AGDYTCVAIN--EAGRA---TGKITLDVGSPPVFIQEPADVSMEIGSNV 810
Query: 770 ELHCEALRG--SPLILYR------FFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEA 821
L C ++G P I +R F ++ + S GA L+L A G Y CEA
Sbjct: 811 TLPCY-VQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869
Query: 822 DNGLGAQRSETVTLYITGLTA 842
+N G +SET T+ +TGL A
Sbjct: 870 ENQFGKIQSET-TVTVTGLVA 889
Score = 56.2 bits (134), Expect = 1e-07
Identities = 136/578 (23%), Positives = 200/578 (34%), Gaps = 62/578 (10%)
Query: 290 TLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL---RHKSVRCERGASISFSLT 346
++ E+ +G+ ++ C T ++ + +G PL H +V
Sbjct: 3439 SMGTEEITVLKGSSTSMACITDGTPAPSM-AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLI--FEGAKVTLHCEAQ 404
TE+SG Y C A N G + SK L V P P +N S + I + L C A
Sbjct: 3498 TEDSGKYTCIASNEAG-EVSKHFILKVLEP---PHINGSEEHEEISVIVNNPLELTCIAS 3553
Query: 405 RGSLPILYQFHHEGAALERRSANSAGGVAISFSLTA--EHSGNYYCTADNGFGPQRSKAV 462
P + + + GG + TA E +G Y C A + G K
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDD-DKEY 3612
Query: 463 SLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSV 522
+ V VP + T + VTL C+ P ++ + + +TP V
Sbjct: 3613 LVRVHVP-PNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER---LQATPRV 3668
Query: 523 -----GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQA 577
GR + G + NY C A N G E + L V VP P +
Sbjct: 3669 RILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFI-LTVNVP---PNIKGGPQSLVI 3724
Query: 578 VVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEH---SGNYSC 634
++ L C A P + W V G+ + S E F L + + H +G Y C
Sbjct: 3725 LLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLC 3783
Query: 635 EANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW-- 692
A N I L V VP P + +V L CEA P + W
Sbjct: 3784 MATNAAGTDRR-RIDLQVHVP---PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 693 ---FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPV 749
+ D S G +S + + + Y C NG + V L V VP
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVI-ISPSVDDTATYECTVTNGAGDDK-RTVDLTVQVPP 3897
Query: 750 SRP------VLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSP---- 799
S ++T AP + C A G P + + L R
Sbjct: 3898 SIADEPTDFLVTKHAPAV---------ITCTA-SGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 800 SGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYI 837
S GA L+ H+G Y+C A N G+ VTL++
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRH-VTLHV 3984
Score = 51.6 bits (122), Expect = 4e-06
Identities = 107/473 (22%), Positives = 181/473 (38%), Gaps = 86/473 (18%)
Query: 40 VTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNILE--------VQ--ESGEYRCQAQG 89
+TL+C+ P T W+ G+ I+ +L VQ ++G Y C A
Sbjct: 4096 ITLSCEADGLPPPDIT-WHKD--GRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 90 SPLSSPVHLDFSSASLILQAP---------LSVFEGDSVVLRCRAKAEVT--LNNTIYKN 138
SS +S L + P +V E +L C A T +N +K
Sbjct: 4153 VAGSSS-----TSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---WKK 4204
Query: 139 DNVLA--FLNKRT-----DFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTR 191
DNVL L K T + + + L+D+G Y C + + ++ + V FT
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTE 4264
Query: 192 PVLRASSFQPISGNPVTLTCETQ--------LSLERSDVPLRFRFFRDDQTLGLGWSLSP 243
G + L+C+ + + +P F L
Sbjct: 4265 ---LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSEL-------- 4313
Query: 244 NFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLS-PEKALNFEGT 302
I + +DSG Y C A SV ++ V+ P PV P + G
Sbjct: 4314 --VIERVSKEDSGTYVCTAEN---SVGFVKAIGFVYVKEP---PVFKGDYPSNWIEPLGG 4365
Query: 303 KVTLHCETQEDSLRTLYRFYHEGVPLR--HKSVRCERGASISFSLTTENSGNYYCTADNG 360
L+CE + D T+ ++ +GV + H+ + G+ + E++G+Y C A N
Sbjct: 4366 NAILNCEVKGDPTPTI-QWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNE 4424
Query: 361 LGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAA 420
G +++SL++ P P++ L E +I G K+ L+C+A P + + +G +
Sbjct: 4425 AGVV-ERSMSLTLQSP---PIITLEPVETVINAGGKIILNCQATGEPQPTI-TWSRQGHS 4479
Query: 421 L---ERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPV 470
+ +R + S + I+ E + + C A N G S+ V VPV
Sbjct: 4480 ISWDDRVNVLSNNSLYIA-DAQKEDTSEFECVARNLMG-------SVLVRVPV 4524
>gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Homo
sapiens]
Length = 323
Score = 111 bits (278), Expect = 3e-24
Identities = 73/198 (36%), Positives = 98/198 (49%), Gaps = 8/198 (4%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW +L LAPV+G A P+ ++ L+P W V Q + VTLTC+G W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIPWFHN 87
Query: 61 YLGKEILRETPDNI---LEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAP-LSVFEG 116
G I T + +SGEY CQ + LS PVHL S L+LQ P L EG
Sbjct: 88 --GNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEG 145
Query: 117 DSVVLRCRA-KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCP 175
+++VLRC + K + + T ++N F +F IP A +G Y CTG
Sbjct: 146 ETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG-NIGYTL 204
Query: 176 VSSNTVKIQVQEPFTRPV 193
SS V I VQ P + P+
Sbjct: 205 YSSKPVTITVQAPSSSPM 222
Score = 51.2 bits (121), Expect = 5e-06
Identities = 57/245 (23%), Positives = 94/245 (38%), Gaps = 29/245 (11%)
Query: 674 DLLELHCEALRG-SSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNG 732
D + L C S + WF++ ++ P+ S+ SG Y+C+
Sbjct: 65 DSVTLTCRGTHSPESDSIPWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTG-- 116
Query: 733 LEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
+ S+ V L V L L+ P G+ + L C + + PL+ FF
Sbjct: 117 -QTSLSDPVHLTVL----SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN--- 168
Query: 793 LGNRSSPSGGASLNLSLTA---EHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFA 849
+S + N S+ HSG+Y C + G S+ VT+ + +++ G
Sbjct: 169 --GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMG-II 225
Query: 850 TGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVPAWEELQ 909
V G+ A +AA L+YC +K S + P + EP + A + Q
Sbjct: 226 VAVVTGIAVAAIVAAVVALIYC------RKKRISANSTDPVKAAQFEPPGRQMIAIRKRQ 279
Query: 910 PVYTN 914
P TN
Sbjct: 280 PEETN 284
Score = 49.7 bits (117), Expect = 1e-05
Identities = 60/273 (21%), Positives = 99/273 (36%), Gaps = 30/273 (10%)
Query: 283 PASHP--VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGAS 340
PA+ P VL L P+ + VTL C ++H G + S
Sbjct: 44 PAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIPWFHNG-----NLIPTHTQPS 98
Query: 341 ISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLH 400
F +SG Y C + P LS + + P L EG + L
Sbjct: 99 YRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ-------EGETIVLR 151
Query: 401 CEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSK 460
C + + + F G + ++ + S +I HSG+Y+CT + G+ SK
Sbjct: 152 CHSWKDKPLVKVTFFQNGKS--KKFSRSDPNFSIP-QANHSHSGDYHCTGNIGYTLYSSK 208
Query: 461 AVSLSVTVPVSHPV-----LTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLW 515
V+++V P S P+ + A A ++C +R S + P+
Sbjct: 209 PVTITVQAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRISA-------NSTDPVK 261
Query: 516 SSSTPSVGRVSFSFSLTE-GHSGNYYCTADNGF 547
++ GR + + + N Y TAD G+
Sbjct: 262 AAQFEPPGRQMIAIRKRQPEETNNDYETADGGY 294
Score = 43.9 bits (102), Expect = 7e-04
Identities = 39/172 (22%), Positives = 70/172 (40%), Gaps = 18/172 (10%)
Query: 599 WFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSR 658
WF++ ++ P+ + S+ SG Y+C+ + SD + L+V+
Sbjct: 84 WFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTGQTSL---SDPVHLTVL----S 130
Query: 659 PILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLT 718
L + P + G+ + L C + + + F+ GK S +F++
Sbjct: 131 EWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN----GKSKKFSRSDPNFSIPQA 186
Query: 719 TE-HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLL 769
HSG Y C + G S+ VT+ V P S P+ + A T AV ++
Sbjct: 187 NHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIV 238
Score = 43.1 bits (100), Expect = 0.001
Identities = 43/190 (22%), Positives = 69/190 (36%), Gaps = 21/190 (11%)
Query: 381 VLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTA 440
VL L + + VTL C + H G + + S F
Sbjct: 51 VLKLEPQWINVLQEDSVTLTCRGTHSPESDSIPWFHNGNLIPTHTQPS-----YRFKANN 105
Query: 441 EHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGS 500
SG Y C ++S V + V L L + EG T+ L C +
Sbjct: 106 NDSGEYTCQTGQ-------TSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDK 158
Query: 501 PQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG---HSGNYYCTADNGFGPQRSEVVSL 557
P + F+ + + R +FS+ + HSG+Y+CT + G+ S+ V++
Sbjct: 159 PLVKVTFFQ------NGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTI 212
Query: 558 FVTVPVSRPI 567
V P S P+
Sbjct: 213 TVQAPSSSPM 222
>gi|132814489 low affinity immunoglobulin gamma Fc region receptor
III-B precursor [Homo sapiens]
Length = 233
Score = 110 bits (275), Expect = 6e-24
Identities = 76/209 (36%), Positives = 108/209 (51%), Gaps = 16/209 (7%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ--KTKWY 58
+LL LL+L + P+ ++FL+P W +V + + VTL C+G YSP+ T+W+
Sbjct: 4 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQG--AYSPEDNSTQWF 61
Query: 59 HRYLGKEILRETPDNIL----EVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVF 114
H + ++ + V +SGEYRCQ S LS PV L+ L+LQAP VF
Sbjct: 62 H---NENLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVF 118
Query: 115 -EGDSVVLRCRAKAEVTLNNTIY-KNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKES 172
E D + LRC + L+ Y +N + + +DFHIP A LKD+G+Y C G S
Sbjct: 119 KEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGS 178
Query: 173 CCPVSSNTVKIQVQEPFTRPVLRASSFQP 201
VSS TV I + + V SSF P
Sbjct: 179 -KNVSSETVNITITQGLA--VSTISSFSP 204
Score = 37.7 bits (86), Expect = 0.053
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 18/182 (9%)
Query: 112 SVFEGDSVVLRCRAKAEVTLNNTI-YKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYK 170
SV E DSV L+C+ N+T + N+N+++ ++ + + I A + D+G YRC
Sbjct: 36 SVLEKDSVTLKCQGAYSPEDNSTQWFHNENLIS--SQASSYFIDAATVNDSGEYRC---- 89
Query: 171 ESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFR 230
++ S+ V+++V + +L+A + +P+ L C + + V + +
Sbjct: 90 QTNLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHLRCHSWKNTALHKVTY-LQNGK 146
Query: 231 DDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLT 290
D + + + +F I KDSG Y+C+ +V S++ + + I V T
Sbjct: 147 DRKY----FHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSET----VNITITQGLAVST 198
Query: 291 LS 292
+S
Sbjct: 199 IS 200
>gi|110347451 platelet/endothelial cell adhesion molecule [Homo
sapiens]
Length = 738
Score = 109 bits (273), Expect = 1e-23
Identities = 161/703 (22%), Positives = 278/703 (39%), Gaps = 82/703 (11%)
Query: 299 FEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTAD 358
F T H + Q L FY + V + S + + +SG Y CT
Sbjct: 58 FADVSTTSHVKPQHQML-----FYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVI 112
Query: 359 NGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFH--- 415
K + L V V P + L E + +G V ++C PI +
Sbjct: 113 VNNKEKTTAEYQLLVE-GVPSPRVTLDKKEAI--QGGIVRVNCSVPEEKAPIHFTIEKLE 169
Query: 416 -HEGAALERRSANSAGGVAISFSLTAEHSG---NYYCTAD--NGFGPQRSKAVS---LSV 466
+E +R NS + E ++ C A +G Q S++ ++V
Sbjct: 170 LNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTV 229
Query: 467 TVPVSHPVLTLSSAEALTFEGATVTLHCEVQ-----RGSPQILYQFYHEDMPLWSSSTPS 521
T S P +S + EGA + + C +Q + P+I+ Q +D + + +
Sbjct: 230 TESFSTPKFHISPT-GMIMEGAQLHIKCTIQVTHLAQEFPEIIIQ---KDKAIVAHNRHG 285
Query: 522 VGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGD 581
V ++ E HSGNY C ++ + S +V + +T S+P L G+
Sbjct: 286 NKAVYSVMAMVE-HSGNYTCKVESSRISKVSSIV-VNITELFSKPELESSFTHLDQ--GE 341
Query: 582 LLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLV 641
L L C P G+PP + ED + + F + SG Y C A V
Sbjct: 342 RLNLSCSIP-GAPPANFTIQKEDTIVSQTQ-------DFTKIASKSDSGTYICTAGIDKV 393
Query: 642 AQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLG 701
+ S+T+ + V +S+P +++ A + + + G +E+ CE++ G+ PI Y L
Sbjct: 394 VKKSNTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLE 452
Query: 702 KISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQR--SEMVTLKVAVPVSRPVLTLRAP 759
+ S A F + T + Y C ADN + SE++ +KV PV +++ +
Sbjct: 453 NSTKNSNDPAVFKDNPTEDVE--YQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSS 510
Query: 760 GTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPSGGAS---LNLSLTAEHSGN 816
+ D++ L C GS I Y+F+ E S + E G
Sbjct: 511 KVVESGEDIV-LQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGE 569
Query: 817 YSC----EADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIAGLAAGALLLYCW 872
Y C A++ RS+ +T+ + L + G A + G ++++ +AA C+
Sbjct: 570 YYCTAFNRANHASSVPRSKILTVRVI-LAPWKKGLIAVVIIGVIIALLIIAA-----KCY 623
Query: 873 LSRKAGRK----PASDPARSPSDSDSQEPTYHNVPAWEE-----------LQPVYTNANP 917
RKA K S PA +S++++ + N+ A ++P+ N P
Sbjct: 624 FLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVRNHAMKPINDNKEP 683
Query: 918 RGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVA 960
+V Y+EV++ + A + L K + +YSEV+ A
Sbjct: 684 LNSDVQYTEVQV-------SSAESHKDLGKKDTETVYSEVRKA 719
Score = 96.3 bits (238), Expect = 1e-19
Identities = 132/575 (22%), Positives = 234/575 (40%), Gaps = 61/575 (10%)
Query: 203 SGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSL---SPNFQITAMWSKDSGFYW 259
+G +TL C +S P F D L S + ++ I + DSG Y
Sbjct: 49 NGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYK 108
Query: 260 CKAATMPYSVISDSPRSWIQVQIPAS---HPVLTLSPEKALNFEGTKVTLHCETQEDSLR 316
C ++++ ++ + Q+ P +TL ++A+ +G V ++C E+ +
Sbjct: 109 CTV------IVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAI--QGGIVRVNCSVPEE--K 158
Query: 317 TLYRFYHEGVPLRHKSVRCERGAS--------ISFSLTTENSG-NYYCTADNGLG----- 362
F E + L K V+ +R + + F + ++ ++ C A G
Sbjct: 159 APIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQT 218
Query: 363 AKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSL----PILYQFHHEG 418
++ +K+ ++VT S P ++S P +I EGA++ + C Q L P + +
Sbjct: 219 SESTKSELVTVTESFSTPKFHIS-PTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKA 277
Query: 419 AALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLS 478
R N A S EHSGNY C ++ + SK S+ V + L
Sbjct: 278 IVAHNRHGNKA---VYSVMAMVEHSGNYTCKVESS---RISKVSSIVVNITELFSKPELE 331
Query: 479 SAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGN 538
S+ +G + L C + G+P + ED + S T +++ ++ SG
Sbjct: 332 SSFTHLDQGERLNLSCSIP-GAPPANFTIQKEDTIV--SQTQDFTKIA-----SKSDSGT 383
Query: 539 YYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILY 598
Y CTA ++S V + V +S+P ++ + + + G +E+ CE+ G+ PI Y
Sbjct: 384 YICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISY 442
Query: 599 WFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANN--GLVAQHSDTISLSVIVPV 656
L +S+ S A F + T + Y C A+N S+ + + VI PV
Sbjct: 443 QLLKTSKVLENSTKNSNDPAVFKDNPTEDVE--YQCVADNCHSHAKMLSEVLRVKVIAPV 500
Query: 657 SRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASF--N 714
++ + + G+ + L C GS PI Y FY E S +F
Sbjct: 501 DEVQISILSSKV-VESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTK 559
Query: 715 LSLTTEHSGIYSC----EADNGLEAQRSEMVTLKV 745
+ E G Y C A++ RS+++T++V
Sbjct: 560 QKASKEQEGEYYCTAFNRANHASSVPRSKILTVRV 594
Score = 89.4 bits (220), Expect = 2e-17
Identities = 138/580 (23%), Positives = 230/580 (39%), Gaps = 68/580 (11%)
Query: 112 SVFEGDSVVLRCRAKAEVTLN-----NTIYKNDNVLAF----LNKRTDFHIPHACLKDNG 162
+V G ++ L+C A T + ++ D+VL + + + IP + D+G
Sbjct: 46 TVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSG 105
Query: 163 AYRCT-----------GYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTC 211
Y+CT Y+ V S V + +E ++R + P P+ T
Sbjct: 106 TYKCTVIVNNKEKTTAEYQLLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTI 165
Query: 212 ETQLSLERSDVPL-RFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMP--YS 268
E +L L V L R + RD + L + + ++ + + C+A + +
Sbjct: 166 E-KLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLS--------FRCQARIISGIHM 216
Query: 269 VISDSPRS-WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVP 327
S+S +S + V S P +SP + EG ++ + C Q + L + + E +
Sbjct: 217 QTSESTKSELVTVTESFSTPKFHISP-TGMIMEGAQLHIKCTIQ---VTHLAQEFPEIII 272
Query: 328 LRHKSV----RCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLN 383
+ K++ R A S E+SGNY C ++ +K S V +++T S P L
Sbjct: 273 QKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIV-VNITELFSKPELE 331
Query: 384 LSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHS 443
S + +G ++ L C G+ P + E + + + + S
Sbjct: 332 SSFTH--LDQGERLNLSCSIP-GAPPANFTIQKEDTIVSQTQ-------DFTKIASKSDS 381
Query: 444 GNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQI 503
G Y CTA ++S V + V +S P ++ A+ +G T+ + CE G+ I
Sbjct: 382 GTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISY-DAQFEVIKGQTIEVRCESISGTLPI 440
Query: 504 LYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADN--GFGPQRSEVVSLFVTV 561
YQ L +S+ S F + TE Y C ADN SEV+ + V
Sbjct: 441 SYQLLKTSKVLENSTKNSNDPAVFKDNPTE--DVEYQCVADNCHSHAKMLSEVLRVKVIA 498
Query: 562 PVSR---PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEA 618
PV IL+ +V + G+ + L C GS PI Y FY E S
Sbjct: 499 PVDEVQISILSSKVVES----GEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQ 554
Query: 619 SF--NLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPV 656
+F + E G Y C A N A H+ ++ S I+ V
Sbjct: 555 AFWTKQKASKEQEGEYYCTAFNR--ANHASSVPRSKILTV 592
Score = 38.1 bits (87), Expect = 0.041
Identities = 59/265 (22%), Positives = 106/265 (40%), Gaps = 49/265 (18%)
Query: 27 LQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKE--ILRETPD--NILEVQESGE 82
L+ +T + QGER+ L+C S + + KE I+ +T D I +SG
Sbjct: 330 LESSFTHLDQGERLNLSC------SIPGAPPANFTIQKEDTIVSQTQDFTKIASKSDSGT 383
Query: 83 YRCQA-------QGSPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRA-KAEVTLNNT 134
Y C A + + + V S + A V +G ++ +RC + + ++
Sbjct: 384 YICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQ 443
Query: 135 IYKNDNVLAFLNKRTDFHIPHACLKDNGA----YRCTGYK-ESCCPVSSNTVKIQVQEPF 189
+ K VL K ++ A KDN Y+C S + S ++++V P
Sbjct: 444 LLKTSKVLENSTKNSN---DPAVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPV 500
Query: 190 TRPVLRASSFQPI-SGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQIT 248
+ S + + SG + L C ++ P+ ++F+R+ + P +Q+T
Sbjct: 501 DEVQISILSSKVVESGEDIVLQC----AVNEGSGPITYKFYREKEG-------KPFYQMT 549
Query: 249 -----AMWSK------DSGFYWCKA 262
A W+K G Y+C A
Sbjct: 550 SNATQAFWTKQKASKEQEGEYYCTA 574
>gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isoform
4 [Homo sapiens]
Length = 309
Score = 108 bits (269), Expect = 3e-23
Identities = 73/198 (36%), Positives = 99/198 (50%), Gaps = 9/198 (4%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW +L LAPV+G A P+ ++ L+P W V Q + VTLTC+G +W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPA-PPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 86
Query: 61 YLGKEILRETPDNI---LEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAP-LSVFEG 116
G I T + +SGEY CQ + LS PVHL S L+LQ P L EG
Sbjct: 87 --GNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEG 144
Query: 117 DSVVLRCRA-KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCP 175
+++VLRC + K + + T ++N F +F IP A +G Y CTG
Sbjct: 145 ETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG-NIGYTL 203
Query: 176 VSSNTVKIQVQEPFTRPV 193
SS V I VQ P + P+
Sbjct: 204 YSSKPVTITVQAPSSSPM 221
Score = 48.1 bits (113), Expect = 4e-05
Identities = 43/187 (22%), Positives = 70/187 (37%), Gaps = 15/187 (8%)
Query: 288 VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTT 347
VL L P+ + VTL C +++H G + S F
Sbjct: 50 VLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNG-----NLIPTHTQPSYRFKANN 104
Query: 348 ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGS 407
+SG Y C + P LS + + P L EG + L C + +
Sbjct: 105 NDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ-------EGETIVLRCHSWKDK 157
Query: 408 LPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVT 467
+ F G + ++ + S +I HSG+Y+CT + G+ SK V+++V
Sbjct: 158 PLVKVTFFQNGKS--KKFSRSDPNFSIP-QANHSHSGDYHCTGNIGYTLYSSKPVTITVQ 214
Query: 468 VPVSHPV 474
P S P+
Sbjct: 215 APSSSPM 221
Score = 48.1 bits (113), Expect = 4e-05
Identities = 47/202 (23%), Positives = 79/202 (39%), Gaps = 23/202 (11%)
Query: 674 DLLELHCEALRG-SSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNG 732
D + L C S + WF++ ++ P+ S+ SG Y+C+
Sbjct: 64 DSVTLTCRGTHSPESDSIQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTG-- 115
Query: 733 LEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
+ S+ V L V L L+ P G+ + L C + + PL+ FF
Sbjct: 116 -QTSLSDPVHLTVL----SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN--- 167
Query: 793 LGNRSSPSGGASLNLSLTA---EHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFA 849
+S + N S+ HSG+Y C + G S+ VT+ + +++ G
Sbjct: 168 --GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMG-II 224
Query: 850 TGVAGGLLSIAGLAAGALLLYC 871
V G+ A +AA L+YC
Sbjct: 225 VAVVTGIAVAAIVAAVVALIYC 246
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/190 (23%), Positives = 70/190 (36%), Gaps = 21/190 (11%)
Query: 381 VLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTA 440
VL L + + VTL C Q+ H G + + S F
Sbjct: 50 VLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANN 104
Query: 441 EHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGS 500
SG Y C ++S V + V L L + EG T+ L C +
Sbjct: 105 NDSGEYTCQTGQ-------TSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDK 157
Query: 501 PQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG---HSGNYYCTADNGFGPQRSEVVSL 557
P + F+ + + R +FS+ + HSG+Y+CT + G+ S+ V++
Sbjct: 158 PLVKVTFFQ------NGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTI 211
Query: 558 FVTVPVSRPI 567
V P S P+
Sbjct: 212 TVQAPSSSPM 221
Score = 44.7 bits (104), Expect = 4e-04
Identities = 43/191 (22%), Positives = 77/191 (40%), Gaps = 23/191 (12%)
Query: 597 LYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPV 656
+ WF++ ++ P+ + S+ SG Y+C+ + SD + L+V+
Sbjct: 81 IQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTGQTSL---SDPVHLTVL--- 128
Query: 657 SRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLS 716
L + P + G+ + L C + + + F+ GK S +F++
Sbjct: 129 -SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN----GKSKKFSRSDPNFSIP 183
Query: 717 LTTE-HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLE----- 770
HSG Y C + G S+ VT+ V P S P+ + A T AV ++
Sbjct: 184 QANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIVAAVVAL 243
Query: 771 LHCEALRGSPL 781
++C R S L
Sbjct: 244 IYCRKKRISAL 254
>gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isoform
2 [Homo sapiens]
Length = 290
Score = 108 bits (269), Expect = 3e-23
Identities = 73/198 (36%), Positives = 99/198 (50%), Gaps = 9/198 (4%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHR 60
MLLW +L LAPV+G A P+ ++ L+P W V Q + VTLTC+G +W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPA-PPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHN 86
Query: 61 YLGKEILRETPDNI---LEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAP-LSVFEG 116
G I T + +SGEY CQ + LS PVHL S L+LQ P L EG
Sbjct: 87 --GNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEG 144
Query: 117 DSVVLRCRA-KAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCP 175
+++VLRC + K + + T ++N F +F IP A +G Y CTG
Sbjct: 145 ETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTG-NIGYTL 203
Query: 176 VSSNTVKIQVQEPFTRPV 193
SS V I VQ P + P+
Sbjct: 204 YSSKPVTITVQAPSSSPM 221
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/217 (23%), Positives = 83/217 (38%), Gaps = 23/217 (10%)
Query: 674 DLLELHCEALRG-SSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNG 732
D + L C S + WF++ ++ P+ S+ SG Y+C+
Sbjct: 64 DSVTLTCRGTHSPESDSIQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTG-- 115
Query: 733 LEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
+ S+ V L V L L+ P G+ + L C + + PL+ FF
Sbjct: 116 -QTSLSDPVHLTVL----SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN--- 167
Query: 793 LGNRSSPSGGASLNLSLTA---EHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFA 849
+S + N S+ HSG+Y C + G S+ VT+ + +++ G
Sbjct: 168 --GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMG-II 224
Query: 850 TGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPA 886
V G+ A +AA L+YC R + D A
Sbjct: 225 VAVVTGIAVAAIVAAVVALIYCRKKRISANPTNPDEA 261
Score = 48.1 bits (113), Expect = 4e-05
Identities = 43/187 (22%), Positives = 70/187 (37%), Gaps = 15/187 (8%)
Query: 288 VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTT 347
VL L P+ + VTL C +++H G + S F
Sbjct: 50 VLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNG-----NLIPTHTQPSYRFKANN 104
Query: 348 ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGS 407
+SG Y C + P LS + + P L EG + L C + +
Sbjct: 105 NDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ-------EGETIVLRCHSWKDK 157
Query: 408 LPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVT 467
+ F G + ++ + S +I HSG+Y+CT + G+ SK V+++V
Sbjct: 158 PLVKVTFFQNGKS--KKFSRSDPNFSIP-QANHSHSGDYHCTGNIGYTLYSSKPVTITVQ 214
Query: 468 VPVSHPV 474
P S P+
Sbjct: 215 APSSSPM 221
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/190 (23%), Positives = 70/190 (36%), Gaps = 21/190 (11%)
Query: 381 VLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTA 440
VL L + + VTL C Q+ H G + + S F
Sbjct: 50 VLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANN 104
Query: 441 EHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGS 500
SG Y C ++S V + V L L + EG T+ L C +
Sbjct: 105 NDSGEYTCQTGQ-------TSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDK 157
Query: 501 PQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG---HSGNYYCTADNGFGPQRSEVVSL 557
P + F+ + + R +FS+ + HSG+Y+CT + G+ S+ V++
Sbjct: 158 PLVKVTFFQ------NGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTI 211
Query: 558 FVTVPVSRPI 567
V P S P+
Sbjct: 212 TVQAPSSSPM 221
Score = 44.3 bits (103), Expect = 6e-04
Identities = 39/174 (22%), Positives = 71/174 (40%), Gaps = 18/174 (10%)
Query: 597 LYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPV 656
+ WF++ ++ P+ + S+ SG Y+C+ + SD + L+V+
Sbjct: 81 IQWFHNGNLI------PTHTQPSYRFKANNNDSGEYTCQTGQTSL---SDPVHLTVL--- 128
Query: 657 SRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLS 716
L + P + G+ + L C + + + F+ GK S +F++
Sbjct: 129 -SEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN----GKSKKFSRSDPNFSIP 183
Query: 717 LTTE-HSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLL 769
HSG Y C + G S+ VT+ V P S P+ + A T AV ++
Sbjct: 184 QANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIV 237
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 107 bits (268), Expect = 4e-23
Identities = 178/816 (21%), Positives = 311/816 (38%), Gaps = 78/816 (9%)
Query: 108 QAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFH----IPHACLKDNGA 163
Q SV G V C AK++ ++ + + DF+ I + L D G
Sbjct: 1778 QRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGT 1837
Query: 164 YRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVP 223
Y CTG + T+ +Q + PV+ Q ++ P L E + S S P
Sbjct: 1838 YVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQ-LTVQPGQLA-EFRCSATGSPTP 1895
Query: 224 LRFRFFRDDQTLGLGWSLSPNFQI-------TAMWSKDSGFYWCKAATMPYSVISDSPRS 276
+ T G G L QI A+ D Y C+A + ++ R+
Sbjct: 1896 TL------EWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVA---RA 1946
Query: 277 WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTL-YRFYHEGVPLRHKSVRC 335
+ V P + +SPE+ G V L+C T+ +R +P + +S R
Sbjct: 1947 VLHVH-GGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERT 2005
Query: 336 ERGASISFSLTTENSGNYYCTADNGLGAKPSK--AVSLSVTVPVSHPVLNLSSPEDLIFE 393
+ + ++TT ++G Y C A + G ++ V LS + S P + + S + E
Sbjct: 2006 DIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSAS-DASPPPVKIESSSPSVTE 2064
Query: 394 GAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNG 453
G + L+C GS ++ G +L + + + ++ SG Y C +NG
Sbjct: 2065 GQTLDLNCVVA-GSAHAQVTWYRRGGSLPPHTQVHGSRLRLP-QVSPADSGEYVCRVENG 2122
Query: 454 FGPQRSKAVSLSVT-----------VPVSHPVLTLSSAEALTFEGATVTLHCEVQ-RGSP 501
GP+ + ++++SV VP S + + + + EG T+ L+C V +
Sbjct: 2123 SGPKEA-SITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHA 2181
Query: 502 QILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTV 561
Q+ + +P + S+ R+ +T SG Y C GP + V+
Sbjct: 2182 QVTWHKRGGSLPARHQTHGSLLRLH---QVTPADSGEYVCHVVGTSGPLEASVLVTIEAS 2238
Query: 562 PVSRPILTLRVPRAQAVV--GDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSG---- 615
+ PI +R+ + + V G L+L C + + W+ S P+
Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKR------GGSLPARHQVR 2292
Query: 616 GEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPI-----LTFRAPRAQA 670
G + + +G Y C A+NG+ A + T++ + ++ P + +Q
Sbjct: 2293 GSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQV 2352
Query: 671 VVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEA- 729
G L+L+C S + W H+ + + G + SG Y C
Sbjct: 2353 AEGQTLDLNCVVPGQSHAQVTW--HKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVL 2410
Query: 730 DNGLEAQRSEMVTLKVAVPVSR----PVLTLRAPGTHAAVGDLLELHCEALRGSPLILYR 785
+ + + S +VT++ A V P + + + + A G L+L+C + G
Sbjct: 2411 GSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC-LVAGQAHAQVT 2469
Query: 786 FFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRS 845
+ +L R G L +T SG Y C G Q + + + S
Sbjct: 2470 WHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASV----LVTIQQRLS 2525
Query: 846 GPFATGVAGGL---LSIAGLAAGALL-LYCWLSRKA 877
G + GVA + S A LA G L L C ++ +A
Sbjct: 2526 GSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQA 2561
Score = 101 bits (252), Expect = 3e-21
Identities = 206/922 (22%), Positives = 339/922 (36%), Gaps = 133/922 (14%)
Query: 9 VLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILR 68
VL + P P + ++ +TV +G+ + L+C Q T WY R
Sbjct: 2231 VLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVT-WYKRGGSLPARH 2289
Query: 69 ETPDNILEV-----QESGEYRCQA---------------QGSPLSSPVHLDFSSASLILQ 108
+ + L + ++G+Y C+A QG+ L+ P S I
Sbjct: 2290 QVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPA----GSTQPIRI 2345
Query: 109 APLS--VFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTD--FHIPHACLKDNGAY 164
P S V EG ++ L C + T +K L ++ + A D+G Y
Sbjct: 2346 EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEY 2405
Query: 165 RCTGYKESCCPVSSNTVKIQ----VQEPFTRPVLR--ASSFQPISGNPVTLTC------E 212
C S +S V I+ V P +R +SS Q G + L C
Sbjct: 2406 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH 2465
Query: 213 TQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCK----AATMPYS 268
Q++ + L R L L Q+T DSG Y C+ + T S
Sbjct: 2466 AQVTWHKRGGSLPARHQVHGSRLRL-------LQVTPA---DSGEYVCRVVGSSGTQEAS 2515
Query: 269 VISDSPRSWIQVQIPASH------PVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFY 322
V+ IQ ++ SH PV S +L G + L+C + T+ +
Sbjct: 2516 VLVT-----IQQRLSGSHSQGVAYPVRIESSSASLA-NGHTLDLNCLVASQAPHTITWYK 2569
Query: 323 HEG-VPLRHKSVRCERGASISF-SLTTENSGNYYCTADNGLGAKPSKAV-----SLSVTV 375
G +P RH+ V G+ + +T +SG Y C NG G++ + + S S V
Sbjct: 2570 RGGSLPSRHQIV----GSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHV 2625
Query: 376 PVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAIS 435
P P + + S + EG + L+C R I+ + G+ R + G
Sbjct: 2626 PSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTH--GSHLRL 2683
Query: 436 FSLTAEHSGNYYCTADNGFGPQRSKAV------SLSVTVPVSHPVLTLSSAEALTFEGAT 489
++ SG Y C A+N + V + S + P S + + S+ + EG T
Sbjct: 2684 HQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGET 2743
Query: 490 VTLHCEVQ-RGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFG 548
+ L+C V + Q+ + +P + S R+ ++ SG Y C G
Sbjct: 2744 LDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHH---VSPADSGEYVCRVMGSSG 2800
Query: 549 PQRSEVV---------SLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYW 599
P + V+ ++ V P P + + ++ G L+L C P + + W
Sbjct: 2801 PLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTW 2860
Query: 600 FYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIV----- 654
+ L + G N A+ SG YSC+ V S T+ SV+V
Sbjct: 2861 -HKRGGNLPARHQVHGPLLRLNQVSPAD-SGEYSCQ-----VTGSSGTLEASVLVTIEPS 2913
Query: 655 ---PVSRPILT----FRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPS 707
P+ P L A + G L+L+C + G + +Y +L
Sbjct: 2914 SPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VVPGQAHAQVTWYKRGGSLPARHQTH 2972
Query: 708 GGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSR--------PVLTLRAP 759
G +L ++ SG Y C A +G ++ T V VP S PV+++ P
Sbjct: 2973 GSQLRLHL-VSPADSGEYVCRAASGPGPEQEASFT--VTVPPSEGSSYRLRSPVISIDPP 3029
Query: 760 GTHAAVGDLLELHCEALRGS-PLIL-YRFFHEDVTLGNRSSPSGGASLNLSLTAEHSGNY 817
+ G C G+ P+ L ++ ++++ SP+G + + G Y
Sbjct: 3030 SSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTY 3089
Query: 818 SCEADNGLGAQRSETVTLYITG 839
C A N G +S V L + G
Sbjct: 3090 RCVASNAYGVAQS-VVNLSVHG 3110
Score = 96.3 bits (238), Expect = 1e-19
Identities = 184/799 (23%), Positives = 296/799 (37%), Gaps = 110/799 (13%)
Query: 112 SVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFH-----IPHACLKDNGAYRC 166
SV EG ++ L C T Y+ L T H +P D+G Y C
Sbjct: 2061 SVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP---PHTQVHGSRLRLPQVSPADSGEYVC 2117
Query: 167 -----TGYKESCCPVS----SNTVKIQVQEP-FTRPV-LRASSFQPISGNPVTLTC---- 211
+G KE+ VS +++ P TRP+ + SS G + L C
Sbjct: 2118 RVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPG 2177
Query: 212 --ETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCK----AATM 265
Q++ + L R QT G SL Q+T DSG Y C + +
Sbjct: 2178 QAHAQVTWHKRGGSLPARH----QTHG---SLLRLHQVTPA---DSGEYVCHVVGTSGPL 2227
Query: 266 PYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEG 325
SV+ S IP P + + + EG + L C + + + G
Sbjct: 2228 EASVLVTIEAS----VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGG 2283
Query: 326 -VPLRHKSVRCERGASIS-FSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPV-- 381
+P RH+ RG+ + F + ++G Y C A NG+ A + V+ + +++P
Sbjct: 2284 SLPARHQV----RGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGS 2339
Query: 382 ---LNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSL 438
+ + + EG + L+C G +H G +L R + G + +
Sbjct: 2340 TQPIRIEPSSSQVAEGQTLDLNCVVP-GQSHAQVTWHKRGGSLPVRH-QTHGSLLRLYQA 2397
Query: 439 TAEHSGNYYCTADNGFGP-QRSKAVSL----SVTVPVSHPVLTLSSAEALTFEGATVTLH 493
+ SG Y C P + S V++ SV P + + S+ + EG T+ L+
Sbjct: 2398 SPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLN 2457
Query: 494 CEVQ-RGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRS 552
C V + Q+ + +P S R+ +T SG Y C G Q +
Sbjct: 2458 CLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRL---LQVTPADSGEYVCRVVGSSGTQEA 2514
Query: 553 EVVSLFVTVP----------VSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYH 602
V+ VT+ V+ P+ + A G L+L+C +P + W Y
Sbjct: 2515 SVL---VTIQQRLSGSHSQGVAYPV-RIESSSASLANGHTLDLNCLVASQAPHTITW-YK 2569
Query: 603 EDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTI-----SLSVIVPVS 657
+L S G +T SG Y C +NG ++ + I S S VP
Sbjct: 2570 RGGSLPSRHQIVGSRLRIP-QVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSV 2628
Query: 658 RPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSL 717
P + + V G L+L+C R I+ W Y +L G + +
Sbjct: 2629 SPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITW-YKRGGSLPSRHQTHGSHLRLH-QM 2686
Query: 718 TTEHSGIYSCEADNGLEAQRSEMVTL------KVAVPVSRPVLTLRAPGTHAAVGDLLEL 771
+ SG Y C A+N ++A + +V + P S + + + +H A G+ L+L
Sbjct: 2687 SVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDL 2746
Query: 772 HCEALRGSPLILYRFFHEDVTLGNR--SSPSGGASLNLSLTAEH-----SGNYSCEADNG 824
+C ++ H VT R S PS + L H SG Y C
Sbjct: 2747 NC--------VVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGS 2798
Query: 825 LG-AQRSETVTLYITGLTA 842
G + S VT+ +G +A
Sbjct: 2799 SGPLEASVLVTIEASGSSA 2817
Score = 94.4 bits (233), Expect = 5e-19
Identities = 192/822 (23%), Positives = 288/822 (35%), Gaps = 102/822 (12%)
Query: 79 ESGEYRCQAQGS--PLSSPVHLDFS---SASLILQAP------------LSVFEGDSVVL 121
+SGEY C+ GS PL + V + S+++ + AP V EG ++ L
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2846
Query: 122 RCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLK-----DNGAYRCTGYKESCCPV 176
+C + T +K L R H P L D+G Y C S
Sbjct: 2847 KCVVPGQAHAQVTWHKRGGNLP---ARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLE 2903
Query: 177 SSNTVKIQVQEPFTRPV--------LRASSFQPISGNPVTLTC------ETQLSLERSDV 222
+S V I+ P P + ASS G + L C Q++ +
Sbjct: 2904 ASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGG 2963
Query: 223 PLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQI 282
L R QT G ++ + DSG Y C+AA+ P + V +
Sbjct: 2964 SLPARH----QTHG------SQLRLHLVSPADSGEYVCRAASGP----GPEQEASFTVTV 3009
Query: 283 PASH--------PVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVR 334
P S PV+++ P + +G + C + + + L
Sbjct: 3010 PPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHI 3069
Query: 335 CERGASISFSLTT-ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFE 393
G+ I+ T N G Y C A N G S V+LSV P + VL PE ++
Sbjct: 3070 SPNGSIITIVGTRPSNHGTYRCVASNAYGVAQS-VVNLSVHGPPTVSVL----PEGPVWV 3124
Query: 394 --GAKVTLHCEA--QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHS--GNYY 447
G VTL C + + S + A LE+R+ A+ +A+ S G Y
Sbjct: 3125 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 3184
Query: 448 CTADNGFGPQRSKAVSLSVTVPVSH--PVLTLSSAEALTFEGATVTLHCEVQRGSPQILY 505
C A N G + + + T ++ P + AE G T TL C GSP
Sbjct: 3185 CLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSAT-GSPAPTI 3243
Query: 506 QFYHEDMPL-WSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVS 564
+ PL W G + + SG Y C A + G + ++ L V P
Sbjct: 3244 HWSKLRSPLPWQHRLE--GDTLIIPRVAQQDSGQYICNATSPAGHAEATII-LHVESP-- 3298
Query: 565 RPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSL 624
P T A G+ ++L C A G+PP+ + + +L + F +
Sbjct: 3299 -PYATTVPEHASVQAGETVQLQCLA-HGTPPLTFQWSRVGSSLPGRATARNELLHFERA- 3355
Query: 625 TAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAV----------VGD 674
E SG Y C N + + + L P S P + A V +G
Sbjct: 3356 APEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGA 3415
Query: 675 LLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGL- 733
+E HC L WF S G NL + + G Y C+A
Sbjct: 3416 SVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQ--GTYICQAHGPWG 3473
Query: 734 EAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTL 793
+AQ S + ++ V ++ +R VG +E C AL G P + L
Sbjct: 3474 KAQASAQLVIQALPSV---LINIRTSVQTVVVGHAVEFECLAL-GDPKPQVTWSKVGGHL 3529
Query: 794 GNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTL 835
SGG + +G Y C A N G +S + L
Sbjct: 3530 RPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLL 3571
Score = 93.2 bits (230), Expect = 1e-18
Identities = 184/885 (20%), Positives = 321/885 (36%), Gaps = 114/885 (12%)
Query: 23 PIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDN-------IL 75
P++ + PP TV G+ C SP T + G ++ + + +
Sbjct: 1866 PVVSIHPPQLTVQPGQLAEFRCSATG--SPTPTLEWTGGPGGQLPAKAQIHGGILRLPAV 1923
Query: 76 EVQESGEYRCQAQGSP----LSSPVHLDFSSASLILQAP--LSVFEGDSVVLRCRAKAEV 129
E + +Y C+A S + +H+ + +P V G +V L CRA
Sbjct: 1924 EPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVP 1983
Query: 130 TLNNTIYKNDNVL--AFLNKRTDFH---IPHACLKDNGAYRCTGYKESCCPVSSNTVKIQ 184
+ T K L ++RTD IP D G Y C + P + +IQ
Sbjct: 1984 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCV----ATSPAGTAQARIQ 2039
Query: 185 V-----QEPFTRPV-LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLG 238
V + PV + +SS G + L C S R G
Sbjct: 2040 VVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYR-----------RG 2088
Query: 239 WSLSPNFQI-------TAMWSKDSGFYWC--------KAATMPYSVISDSPRSWIQVQIP 283
SL P+ Q+ + DSG Y C K A++ SV+ + +P
Sbjct: 2089 GSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVP 2148
Query: 284 ASHPVLTLSPEKALNFEGTKVTLHCETQ-EDSLRTLYRFYHEGVPLRHKSVRCERGASIS 342
S + + P + EG + L+C + + + +P RH++ G+ +
Sbjct: 2149 GSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQT----HGSLLR 2204
Query: 343 F-SLTTENSGNYYCTADNGLG-AKPSKAVSLSVTV-PVSHPVLNLSSPEDLIFEGAKVTL 399
+T +SG Y C G + S V++ +V P P + + S + EG + L
Sbjct: 2205 LHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDL 2264
Query: 400 HCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRS 459
C G ++ G +L R G F + +G Y C A NG +
Sbjct: 2265 SC-VVAGQAHAQVTWYKRGGSLPARH-QVRGSRLYIFQASPADAGQYVCRASNGMEASIT 2322
Query: 460 KAVSLSVTVPVSHPV-----LTLSSAEALTFEGATVTLHCEVQ-RGSPQILYQFYHEDMP 513
V+ + +++P + + + + EG T+ L+C V + Q+ + +P
Sbjct: 2323 VTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP 2382
Query: 514 LWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFV---TVPVSRPILTL 570
+ + S+ R+ + + SG Y C P + V+ +VP T+
Sbjct: 2383 VRHQTHGSLLRL---YQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTV 2439
Query: 571 RV--PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEH 628
R+ +Q G L+L+C + + W + +L + G L +T
Sbjct: 2440 RIESSSSQVAEGQTLDLNCLVAGQAHAQVTW-HKRGGSLPARHQVHGSRLRL-LQVTPAD 2497
Query: 629 SGNYSCEANNGLVAQHSDTISLSVIVPVSRPI-----------LTFRAPRAQAVVGDLLE 677
SG Y C V S T SV+V + + + + + A G L+
Sbjct: 2498 SGEYVCR-----VVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLD 2552
Query: 678 LHCEALRGSSPILYWFYHEDVTLGKISAPSGG---GASFNL-SLTTEHSGIYSCEADNGL 733
L+C + + W+ S PS G+ + +T SG Y C NG
Sbjct: 2553 LNCLVASQAPHTITWYKRGG------SLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGA 2606
Query: 734 EAQRSEM-VTLKVA----VPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFH 788
++ + + VT++ + VP P + + + G L+L+C R P + ++
Sbjct: 2607 GSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVAR-QPQAIITWYK 2665
Query: 789 EDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETV 833
+L +R G ++ SG Y C A+N + A + V
Sbjct: 2666 RGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIV 2710
Score = 87.4 bits (215), Expect = 6e-17
Identities = 150/669 (22%), Positives = 251/669 (37%), Gaps = 79/669 (11%)
Query: 149 TDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVL------RASSFQPI 202
++ H P D G Y CT + +++ ++ V E ++P+ R+ S +P
Sbjct: 1729 SELHFPSVQPSDAGVYICTC--RNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP- 1785
Query: 203 SGNPVTLTCETQLS----------LERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWS 252
G VT C + L +P R F T+ N Q++
Sbjct: 1786 -GADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIR-------NVQLS---- 1833
Query: 253 KDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQE 312
D+G Y C + M +++ + +Q S PV+++ P + G C
Sbjct: 1834 -DAGTYVCTGSNM-FAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATG 1891
Query: 313 DSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLS 372
TL G L K+ + G ++ + Y C A + G + ++AV L
Sbjct: 1892 SPTPTLEWTGGPGGQLPAKA-QIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAV-LH 1949
Query: 373 VTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGV 432
V P + +S + G V L+C A G + EG +L ++ + +
Sbjct: 1950 VHGG-GGPRVQVSPERTQVHAGRTVRLYCRAA-GVPSATITWRKEGGSLPPQARSERTDI 2007
Query: 433 AISF--SLTAEHSGNYYCTADN--GFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGA 488
A ++T +G Y C A + G R + V LS + PV SS+ ++T EG
Sbjct: 2008 ATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVT-EGQ 2066
Query: 489 TVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFG 548
T+ L+C V GS +Y L + R+ ++ SG Y C +NG G
Sbjct: 2067 TLDLNCVVA-GSAHAQVTWYRRGGSLPPHTQVHGSRLRLP-QVSPADSGEYVCRVENGSG 2124
Query: 549 PQRSEV-VSL---------FVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILY 598
P+ + + VS+ + VP S + + + G L+L+C P + +
Sbjct: 2125 PKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVT 2184
Query: 599 WFYHEDVTLGSSSAPSGGEASFNL----SLTAEHSGNYSCE---ANNGLVAQHSDTISLS 651
W S P+ + +L +T SG Y C + L A TI S
Sbjct: 2185 WHKR------GGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEAS 2238
Query: 652 VIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISA--PSGG 709
VI P P + + + G L+L C + + W+ G + A G
Sbjct: 2239 VI-PGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG----GSLPARHQVRG 2293
Query: 710 GASFNLSLTTEHSGIYSCEADNGLEAQRSEMVT----LKVAVPV-SRPVLTLRAPGTHAA 764
+ + +G Y C A NG+EA + VT +A P S + + + A
Sbjct: 2294 SRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVA 2353
Query: 765 VGDLLELHC 773
G L+L+C
Sbjct: 2354 EGQTLDLNC 2362
Score = 83.2 bits (204), Expect = 1e-15
Identities = 190/868 (21%), Positives = 299/868 (34%), Gaps = 110/868 (12%)
Query: 23 PIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNILEVQE--- 79
P I ++P + V +G+ + L C Q T W+ R + +L + +
Sbjct: 2827 PPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT-WHKRGGNLPARHQVHGPLLRLNQVSP 2885
Query: 80 --SGEYRCQAQGSP-----------------------LSSPVHLDFSSASLILQAPLSVF 114
SGEY CQ GS L+ P++++ SS+ V
Sbjct: 2886 ADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSH--------VT 2937
Query: 115 EGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKR--TDFHIPHACLKDNGAYRCTGYKES 172
EG ++ L C + T YK L ++ + + D+G Y C
Sbjct: 2938 EGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRA---- 2993
Query: 173 CCPVSSNTVKIQVQEPFTRPVLRASSFQ----PISGNPVTLTCET------QLSLERSDV 222
S + + T P SS++ IS +P + T + + +
Sbjct: 2994 ---ASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 3050
Query: 223 PLRFRFFRDDQTLGLGWSLSPNFQI-TAMWSKDS--GFYWCKAATMPYSVISDSPRSWIQ 279
P+ + +Q L +SPN I T + ++ S G Y C A+ Y V +S +
Sbjct: 3051 PISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNA-YGVA----QSVVN 3105
Query: 280 VQIPASHPVLTLSPEKALNFE-GTKVTLHC----ETQEDSLRTLYRFYHEGVPLRHKSVR 334
+ + P +++ PE + + G VTL C E + + T + R +
Sbjct: 3106 LSVHGP-PTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLM 3164
Query: 335 CERGASISFSLTTENSGNYYCTADNGLGA--KPSKAVSLSVTVPVSHPVLNLSSPEDLIF 392
S ++G Y C A N LG K + + + + P + E +
Sbjct: 3165 DSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVE 3224
Query: 393 EGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADN 452
G TL C A P ++ + G I + + SG Y C A +
Sbjct: 3225 AGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE--GDTLIIPRVAQQDSGQYICNATS 3282
Query: 453 GFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDM 512
G + + L V P P T A G TV L C + G+P + +Q+
Sbjct: 3283 PAGHAEATII-LHVESP---PYATTVPEHASVQAGETVQLQC-LAHGTPPLTFQWSRVGS 3337
Query: 513 PLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTL-- 570
L +T + F + E SG Y C N G + L P S P ++
Sbjct: 3338 SLPGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPA 3396
Query: 571 -RVPRAQAV-------VGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNL 622
P Q +G +E HC P L WF S G NL
Sbjct: 3397 GSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNL 3456
Query: 623 SLTAEHSGNYSCEANNGL-VAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCE 681
+ + G Y C+A+ AQ S + + + V ++ R VVG +E C
Sbjct: 3457 DQSCQ--GTYICQAHGPWGKAQASAQLVIQALPSV---LINIRTSVQTVVVGHAVEFECL 3511
Query: 682 ALRGSSPILYWFYHEDVTLGKISAPS---GGGASFNLSLTTEHSGIYSCEADNGLEAQRS 738
AL P + W +G P GG + +G Y C A N +S
Sbjct: 3512 ALGDPKPQVTWS-----KVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQS 3566
Query: 739 EMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS 798
++ L A+P +R P AAV C A G P + D +L S
Sbjct: 3567 HVLLLVQALPQISMPQEVRVPAGSAAV-----FPCIA-SGYPTPDISWSKLDGSLPPDSR 3620
Query: 799 PSGGASLNLSLTAEHSGNYSCEADNGLG 826
+ S+ + +G Y C A N G
Sbjct: 3621 LENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Score = 78.2 bits (191), Expect = 4e-14
Identities = 155/719 (21%), Positives = 258/719 (35%), Gaps = 72/719 (10%)
Query: 162 GAYRCTG--------YKESCCPVSSNTVKIQV--------QEPFTRPVLRASSFQPISGN 205
G YRCT Y E C P +Q Q P V A S P G+
Sbjct: 1634 GGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSIVPQGGS 1693
Query: 206 PVTLTCETQLSLERSDVPLRFRFFRDD-QTLGLGWSL---SPNFQITAMWSKDSGFYWCK 261
+L C+ S P F + R+D + + G ++ D+G Y C
Sbjct: 1694 H-SLRCQVSGS-----PPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICT 1747
Query: 262 AATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFE-GTKVTLHCETQEDS--LRTL 318
+ S + S + + P+ +T+ +++ + G VT C + S +
Sbjct: 1748 CRNLHQS--NTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLV 1805
Query: 319 YRFYHEG-VPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKA-VSLSVTVP 376
+ H G +P R G ++ ++G Y CT N A + + +
Sbjct: 1806 WTRLHNGKLPTRAMDFN---GILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGT 1862
Query: 377 VSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISF 436
+S PV+++ P+ + G C A P L G L + A GG+
Sbjct: 1863 LSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAK-AQIHGGILRLP 1921
Query: 437 SLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEV 496
++ Y C A + G Q ++AV L V P + +S G TV L+C
Sbjct: 1922 AVEPTDQAQYLCRAHSSAGQQVARAV-LHVHGG-GGPRVQVSPERTQVHAGRTVRLYCRA 1979
Query: 497 QRGSPQILYQFYHE--DMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEV 554
G P + E +P + S + ++T +G Y C A + G ++ +
Sbjct: 1980 A-GVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARI 2038
Query: 555 -VSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAP 613
V + S P + + G L+L+C + + W+ G S P
Sbjct: 2039 QVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRR-----GGSLPP 2093
Query: 614 SGGEASFNLSL---TAEHSGNYSCEANNGLVAQHSDTISLSVI-----------VPVSRP 659
L L + SG Y C NG + + +I++SV+ VP S
Sbjct: 2094 HTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEA-SITVSVLHGTHSGPSYTPVPGSTR 2152
Query: 660 ILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTT 719
+ + G L+L+C + G + ++ +L G + +T
Sbjct: 2153 PIRIEPSSSHVAEGQTLDLNC-VVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLH-QVTP 2210
Query: 720 EHSGIYSCEA---DNGLEAQRSEMVTLKVAV-PVSRPVLTLRAPGTHAAVGDLLELHCEA 775
SG Y C LEA S +VT++ +V P P + + + + A G L+L C
Sbjct: 2211 ADSGEYVCHVVGTSGPLEA--SVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSC-V 2267
Query: 776 LRGSPLILYRFFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVT 834
+ G ++ +L R G + +G Y C A NG+ A + TVT
Sbjct: 2268 VAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVT 2326
Score = 70.5 bits (171), Expect = 7e-12
Identities = 158/695 (22%), Positives = 242/695 (34%), Gaps = 120/695 (17%)
Query: 8 LVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEIL 67
+ + P G R P+I + PP +TV QG+ + C +P +W R
Sbjct: 3007 VTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRN------ 3060
Query: 68 RETPDNI-------------LEVQESGEYRCQAQGS--PLSSPVHLDFS---SASLILQA 109
+E DN+ G YRC A + S V+L + S++ +
Sbjct: 3061 QELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEG 3120
Query: 110 PLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRT----DFH----IPHACLKDN 161
P+ V G +V L C + E + + + A L +RT D H I A D
Sbjct: 3121 PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDA 3180
Query: 162 GAYRCTGYKESCCPVSSNTVKIQVQEPFTRP-----VLRASSFQPISGNPVTLTCET--- 213
G Y C ++ + V++ V P + +G+ TL C
Sbjct: 3181 GTYVCLA--QNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 3238
Query: 214 -----QLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYS 268
S RS +P + R D I + +DSG Y C A
Sbjct: 3239 PAPTIHWSKLRSPLPWQHRLEGD------------TLIIPRVAQQDSGQYICNAT----- 3281
Query: 269 VISDSPRSWIQVQI---PASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEG 325
SP + I S P T PE A G V L C T +++ G
Sbjct: 3282 ----SPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLT-FQWSRVG 3336
Query: 326 VPL------RHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSH 379
L R++ + ER A E+SG Y C N +G+ + A L P S
Sbjct: 3337 SSLPGRATARNELLHFERAAP-------EDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSL 3389
Query: 380 PVLNL---SSPEDLIFE-------GAKVTLHCE--AQRGSLPILYQFHHEGAALERRSAN 427
P ++ S+P + GA V HC + RG+ ++ EG L +
Sbjct: 3390 PATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQ---LRWFKEGGQLPPGHSV 3446
Query: 428 SAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEG 487
G + I +L G Y C A +G ++ A + +P ++ + ++ G
Sbjct: 3447 QDGVLRIQ-NLDQSCQGTYICQAHGPWGKAQASAQLVIQALP--SVLINIRTSVQTVVVG 3503
Query: 488 ATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGF 547
V C + G P+ + L S G V + + +G Y CTA N
Sbjct: 3504 HAVEFEC-LALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAH-VELADAGQYRCTATNAA 3561
Query: 548 GPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTL 607
G +S V+ L +P +RVP A V C A P + W +
Sbjct: 3562 GTTQSHVLLLVQALPQISMPQEVRVPAGSAAV-----FPCIASGYPTPDISW------SK 3610
Query: 608 GSSSAPSGGEASFNL----SLTAEHSGNYSCEANN 638
S P N+ S+ + +G Y C A N
Sbjct: 3611 LDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATN 3645
Score = 55.8 bits (133), Expect = 2e-07
Identities = 114/506 (22%), Positives = 184/506 (36%), Gaps = 66/506 (13%)
Query: 436 FSLTAEH--SGNYYCTADN-----------GFGPQRSKAVSLSVTVPVSHP---VLTLSS 479
FS T E +G Y CTA G G + +V +P ++ V+ +
Sbjct: 1624 FSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHP 1683
Query: 480 AEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSF-SLTEGHSGN 538
A ++ +G + +L C+V P Y + P+ S + F S+ +G
Sbjct: 1684 ARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGV 1743
Query: 539 YYCTADNGFGPQRSEVVSLFVTVPVSRPI-LTLRVPRAQAV-VGDLLELHCEAPRGSPPI 596
Y CT N S L VT S+PI +T+ R+Q+V G + C A SP
Sbjct: 1744 YICTCRNLHQSNTSRA-ELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAY 1802
Query: 597 -LYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVA-QHSDTISLSVIV 654
L W + L + + G + ++ +G Y C +N Q + T+ +
Sbjct: 1803 TLVWTRLHNGKLPTRAMDFNGILTIR-NVQLSDAGTYVCTGSNMFAMDQGTATLHVQASG 1861
Query: 655 PVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFN 714
+S P+++ P+ G L E C A +P L W L + GG
Sbjct: 1862 TLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLP 1921
Query: 715 LSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPG----------THAA 764
T+ + Y C A + Q V+R VL + G T
Sbjct: 1922 AVEPTDQAQ-YLCRAHSSAGQQ------------VARAVLHVHGGGGPRVQVSPERTQVH 1968
Query: 765 VGDLLELHCEALR-GSPLILYRFFHEDVTLGNRSSPSGGASLNL-SLTAEHSGNYSCEAD 822
G + L+C A S I +R + RS + A+L + ++T +G Y C A
Sbjct: 1969 AGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVAT 2028
Query: 823 NGLGAQRSETVTLYITGLTAN-------RSGPFATGVAGGLLSIAGLAAGALLLYCWLSR 875
+ G ++ + ++ A+ S P T G L + + AG+ R
Sbjct: 2029 SPAGTAQARIQVVVLSASDASPPPVKIESSSPSVT--EGQTLDLNCVVAGSAHAQVTWYR 2086
Query: 876 KAGRKPASD---------PARSPSDS 892
+ G P P SP+DS
Sbjct: 2087 RGGSLPPHTQVHGSRLRLPQVSPADS 2112
>gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform c precursor [Homo sapiens]
Length = 254
Score = 107 bits (266), Expect = 7e-23
Identities = 89/269 (33%), Positives = 127/269 (47%), Gaps = 31/269 (11%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ--KTKWY 58
+LL LL+L + P+ ++FL+P W V + + VTL C+G YSP+ T+W+
Sbjct: 4 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQG--AYSPEDNSTQWF 61
Query: 59 HRYLGKEILRETPDNIL----EVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVF 114
H + ++ + V +SGEYRCQ S LS PV L+ L+LQAP VF
Sbjct: 62 H---NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVF 118
Query: 115 -EGDSVVLRCRAKAEVTLNNTIY-KNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKES 172
E D + LRC + L+ Y +N + + +DF+IP A LKD+G+Y C G S
Sbjct: 119 KEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGS 178
Query: 173 CCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDD 232
VSS TV I + + V SSF P G V+ C + L D
Sbjct: 179 -KNVSSETVNITITQGLA--VSTISSFFP-PGYQVSF-CLVMVLLFAVDT---------- 223
Query: 233 QTLGLGWSLSPNFQITAMWSKDSGFYWCK 261
GL +S+ N + + KD F W K
Sbjct: 224 ---GLYFSVKTNIRSSTRDWKDHKFKWRK 249
Score = 32.7 bits (73), Expect = 1.7
Identities = 40/181 (22%), Positives = 82/181 (45%), Gaps = 18/181 (9%)
Query: 113 VFEGDSVVLRCRAKAEVTLNNTI-YKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKE 171
V E DSV L+C+ N+T + N+++++ ++ + + I A + D+G YRC +
Sbjct: 37 VLEKDSVTLKCQGAYSPEDNSTQWFHNESLIS--SQASSYFIDAATVDDSGEYRC----Q 90
Query: 172 SCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRD 231
+ S+ V+++V + +L+A + +P+ L C + + V +
Sbjct: 91 TNLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHLRCHSWKNTALHKVT-----YLQ 143
Query: 232 DQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTL 291
+ + + +F I KDSG Y+C+ +V S++ + + I V T+
Sbjct: 144 NGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSET----VNITITQGLAVSTI 199
Query: 292 S 292
S
Sbjct: 200 S 200
>gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform c precursor [Homo sapiens]
Length = 254
Score = 107 bits (266), Expect = 7e-23
Identities = 89/269 (33%), Positives = 127/269 (47%), Gaps = 31/269 (11%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ--KTKWY 58
+LL LL+L + P+ ++FL+P W V + + VTL C+G YSP+ T+W+
Sbjct: 4 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQG--AYSPEDNSTQWF 61
Query: 59 HRYLGKEILRETPDNIL----EVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVF 114
H + ++ + V +SGEYRCQ S LS PV L+ L+LQAP VF
Sbjct: 62 H---NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVF 118
Query: 115 -EGDSVVLRCRAKAEVTLNNTIY-KNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKES 172
E D + LRC + L+ Y +N + + +DF+IP A LKD+G+Y C G S
Sbjct: 119 KEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGS 178
Query: 173 CCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDD 232
VSS TV I + + V SSF P G V+ C + L D
Sbjct: 179 -KNVSSETVNITITQGLA--VSTISSFFP-PGYQVSF-CLVMVLLFAVDT---------- 223
Query: 233 QTLGLGWSLSPNFQITAMWSKDSGFYWCK 261
GL +S+ N + + KD F W K
Sbjct: 224 ---GLYFSVKTNIRSSTRDWKDHKFKWRK 249
Score = 32.7 bits (73), Expect = 1.7
Identities = 40/181 (22%), Positives = 82/181 (45%), Gaps = 18/181 (9%)
Query: 113 VFEGDSVVLRCRAKAEVTLNNTI-YKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKE 171
V E DSV L+C+ N+T + N+++++ ++ + + I A + D+G YRC +
Sbjct: 37 VLEKDSVTLKCQGAYSPEDNSTQWFHNESLIS--SQASSYFIDAATVDDSGEYRC----Q 90
Query: 172 SCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRD 231
+ S+ V+++V + +L+A + +P+ L C + + V +
Sbjct: 91 TNLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHLRCHSWKNTALHKVT-----YLQ 143
Query: 232 DQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTL 291
+ + + +F I KDSG Y+C+ +V S++ + + I V T+
Sbjct: 144 NGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSET----VNITITQGLAVSTI 199
Query: 292 S 292
S
Sbjct: 200 S 200
>gi|189083836 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform b precursor [Homo sapiens]
Length = 289
Score = 107 bits (266), Expect = 7e-23
Identities = 89/272 (32%), Positives = 129/272 (47%), Gaps = 35/272 (12%)
Query: 2 LLWVILL----VLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ--KT 55
++W +LL +L +G P+ ++FL+P W V + + VTL C+G YSP+ T
Sbjct: 36 IMWQLLLPTALLLLVSAGMRTDLPKAVVFLEPQWYRVLEKDSVTLKCQG--AYSPEDNST 93
Query: 56 KWYHRYLGKEILRETPDNIL----EVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPL 111
+W+H + ++ + V +SGEYRCQ S LS PV L+ L+LQAP
Sbjct: 94 QWFH---NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPR 150
Query: 112 SVF-EGDSVVLRCRAKAEVTLNNTIY-KNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGY 169
VF E D + LRC + L+ Y +N + + +DF+IP A LKD+G+Y C G
Sbjct: 151 WVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGL 210
Query: 170 KESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFF 229
S VSS TV I + + V SSF P G V+ C + L D
Sbjct: 211 FGS-KNVSSETVNITITQGLA--VSTISSFFP-PGYQVSF-CLVMVLLFAVDT------- 258
Query: 230 RDDQTLGLGWSLSPNFQITAMWSKDSGFYWCK 261
GL +S+ N + + KD F W K
Sbjct: 259 ------GLYFSVKTNIRSSTRDWKDHKFKWRK 284
Score = 33.5 bits (75), Expect = 1.00
Identities = 44/203 (21%), Positives = 91/203 (44%), Gaps = 19/203 (9%)
Query: 92 LSSPVHLDFSSASLILQAP-LSVFEGDSVVLRCRAKAEVTLNNTI-YKNDNVLAFLNKRT 149
+S+ + D A + L+ V E DSV L+C+ N+T + N+++++ ++ +
Sbjct: 50 VSAGMRTDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLIS--SQAS 107
Query: 150 DFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTL 209
+ I A + D+G YRC ++ S+ V+++V + +L+A + +P+ L
Sbjct: 108 SYFIDAATVDDSGEYRC----QTNLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHL 161
Query: 210 TCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSV 269
C + + V + + + + +F I KDSG Y+C+ +V
Sbjct: 162 RCHSWKNTALHKVT-----YLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNV 216
Query: 270 ISDSPRSWIQVQIPASHPVLTLS 292
S++ + + I V T+S
Sbjct: 217 SSET----VNITITQGLAVSTIS 235
>gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
isoform a precursor [Homo sapiens]
Length = 290
Score = 107 bits (266), Expect = 7e-23
Identities = 89/269 (33%), Positives = 127/269 (47%), Gaps = 31/269 (11%)
Query: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ--KTKWY 58
+LL LL+L + P+ ++FL+P W V + + VTL C+G YSP+ T+W+
Sbjct: 40 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQG--AYSPEDNSTQWF 97
Query: 59 HRYLGKEILRETPDNIL----EVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVF 114
H + ++ + V +SGEYRCQ S LS PV L+ L+LQAP VF
Sbjct: 98 H---NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVF 154
Query: 115 -EGDSVVLRCRAKAEVTLNNTIY-KNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKES 172
E D + LRC + L+ Y +N + + +DF+IP A LKD+G+Y C G S
Sbjct: 155 KEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGS 214
Query: 173 CCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDD 232
VSS TV I + + V SSF P G V+ C + L D
Sbjct: 215 -KNVSSETVNITITQGLA--VSTISSFFP-PGYQVSF-CLVMVLLFAVDT---------- 259
Query: 233 QTLGLGWSLSPNFQITAMWSKDSGFYWCK 261
GL +S+ N + + KD F W K
Sbjct: 260 ---GLYFSVKTNIRSSTRDWKDHKFKWRK 285
Score = 32.7 bits (73), Expect = 1.7
Identities = 40/181 (22%), Positives = 82/181 (45%), Gaps = 18/181 (9%)
Query: 113 VFEGDSVVLRCRAKAEVTLNNTI-YKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKE 171
V E DSV L+C+ N+T + N+++++ ++ + + I A + D+G YRC +
Sbjct: 73 VLEKDSVTLKCQGAYSPEDNSTQWFHNESLIS--SQASSYFIDAATVDDSGEYRC----Q 126
Query: 172 SCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRD 231
+ S+ V+++V + +L+A + +P+ L C + + V +
Sbjct: 127 TNLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHLRCHSWKNTALHKVT-----YLQ 179
Query: 232 DQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTL 291
+ + + +F I KDSG Y+C+ +V S++ + + I V T+
Sbjct: 180 NGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSET----VNITITQGLAVSTI 235
Query: 292 S 292
S
Sbjct: 236 S 236
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 107 bits (266), Expect = 7e-23
Identities = 197/818 (24%), Positives = 319/818 (38%), Gaps = 121/818 (14%)
Query: 74 ILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSV-----------FEGDSVVLR 122
+L V+++G Y C A+ SP S + +QAP ++ +VL
Sbjct: 2357 VLRVRDAGLYTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLE 2411
Query: 123 CRAKAEVTLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPV 176
C +AE T +++ VL F + + D+G Y CT +
Sbjct: 2412 CSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA---- 2467
Query: 177 SSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSL---ERSDVPLRFRFFRDDQ 233
S +V +V E T P +R SG P Q +L + VP +R D+
Sbjct: 2468 GSTSVAFRV-EIHTVPTIR-------SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDR 2519
Query: 234 T----LGLGWSLSP--NFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHP 287
+ + P + +I + ++D+G Y C A+ S SD ++V P P
Sbjct: 2520 VPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN---SAGSDRQGRDLRVLEP---P 2573
Query: 288 VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGA-----SIS 342
+ SP T L CE S + L ++ +G L R ++GA S +
Sbjct: 2574 AIAPSPSNLTLTAHTPALLPCEAS-GSPKPLVVWWKDGQKL---DFRLQQGAYRLLPSNA 2629
Query: 343 FSLTT---ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTL 399
LT ++S + C N +G + + ++V VP P + + + A V L
Sbjct: 2630 LLLTAPGPQDSAQFECVVSNEVG-EAHRLYQVTVHVP---PTIADDQTDFTVTMMAPVVL 2685
Query: 400 HCEAQRGSLPILYQFHHEGAALERRSA----NSAGGVAISFSLTAEHSGNYYCTADNGFG 455
C + P + + GA L R + + +G + I +L H+G Y C+A N G
Sbjct: 2686 TCHSTGIPAPTV-SWSKAGAQLGARGSGYRVSPSGALEIGQALPI-HAGRYTCSARNSAG 2743
Query: 456 PQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLW 515
PV P+ ++ A A V L CE G P+ + E + +
Sbjct: 2744 VAHKHVFLTVQASPVVKPLPSVVRAVA----EEEVLLPCEAS-GIPRPTITWQKEGLNVA 2798
Query: 516 SSSTPSV---GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRV 572
+ + V G++ + + E +GNY C A N G + L V VP P++ +
Sbjct: 2799 TGVSTQVLPGGQLRIAHASPED-AGNYLCIAKNSAGSAMGKT-RLVVQVP---PVIENGL 2853
Query: 573 PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAP-SGGEASFNL--------- 622
P G L C+A RGSP ++T P SG E F +
Sbjct: 2854 PDLSTTEGSHAFLPCKA-RGSP-------EPNITWDKDGQPVSGAEGKFTIQPSGELLVK 2905
Query: 623 SLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA 682
+L + +G Y+C A N V + + L+++V P+ T +GD L L C A
Sbjct: 2906 NLEGQDAGTYTCTAENA-VGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWLRCAA 2961
Query: 683 LRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGL-EAQRSEMV 741
+P + W ++ +S GG +++ E SG Y C A+N + Q V
Sbjct: 2962 RGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFV 3021
Query: 742 TLKVAVPVSRPVLTLRA-PGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPS 800
+K A PVL A VG ++L C +RG P+ + + + L R S
Sbjct: 3022 HVKEA-----PVLQGEAFSYLVEPVGGSIQLDC-VVRGDPVPDIHWIKDGLPL--RGSHL 3073
Query: 801 GGASLNLSLT-----AEHSGNYSCEADNGLGAQRSETV 833
N SLT + +G Y C A+N +G + +
Sbjct: 3074 RHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVI 3111
Score = 106 bits (264), Expect = 1e-22
Identities = 207/857 (24%), Positives = 326/857 (38%), Gaps = 83/857 (9%)
Query: 19 RTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRY----LGKEILRETPDNI 74
+ P I L T V+L C +P+ T WY LG+E+ +
Sbjct: 1743 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVT-WYKDSQALSLGEEVFLLPGTHT 1801
Query: 75 LEV-----QESGEYRCQAQGSP--------LSSPVHLDFSSASLILQAPLSVFEGDSVVL 121
L++ +SG Y C+A + LS V F A Q + V GD VL
Sbjct: 1802 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVL 1861
Query: 122 RCRAKAEVTLNNTIYKNDNVLAFLNKRTD-------FHIPHACLKDNGAYRCTGYKESCC 174
C A T YK+ L L +RT I A + D G Y C +
Sbjct: 1862 SCETDALPEPTVTWYKDGQPLV-LAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE 1920
Query: 175 PVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQT 234
V + T+ +QV F P + + ++G+P+ LTC+ + L+ R +
Sbjct: 1921 AVRTFTLTVQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA 1978
Query: 235 LGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPE 294
+ S Q++ + +G Y C A + +++ + ++ + A +
Sbjct: 1979 VHGVVSRGGRLQLSRLQPAQAGTYTCVAE----NTQAEARKDFVVAVLVAPRIRSSGVAR 2034
Query: 295 KALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL-----RHKSVRCERGASISFSLTTEN 349
+ EG +V L CE + + +G PL H + G+ + L +
Sbjct: 2035 EHHVLEGQEVRLDCEADGQPPPDV-AWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASD 2093
Query: 350 SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLP 409
+G Y C A N G + ++ +++V VP + S + G VT+ C RGS P
Sbjct: 2094 AGAYTCVAHNPAG-EDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPV-RGSPP 2151
Query: 410 ILYQFHHEGAAL---ERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSV 466
I + +G L +R + +G + +G + C A + G + +L V
Sbjct: 2152 IHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG-VADRNFTLQV 2210
Query: 467 TV-PVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRV 525
V PV PV + + + G+ V L CE RG P L + + PL S S +
Sbjct: 2211 QVPPVLEPVEFQN--DVVVVRGSLVELPCEA-RGVPLPLVSWMKDGEPLLSQSLEQGPSL 2267
Query: 526 SFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVV-GDLLE 584
++ G SG Y C A + G R +TV I P ++ G +E
Sbjct: 2268 QLE-AVGAGDSGTYSCVAVSEAGEARRH---FQLTVMEPPHIEDSGQPTELSLTPGAPME 2323
Query: 585 LHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQH 644
L C+A P + W H+D G + + L +G Y+C L
Sbjct: 2324 LLCDAQGTPQPNITW--HKD---GQALTRLENNSRATRVLRVRDAGLYTC-----LAESP 2373
Query: 645 SDTISLSVIVPVSRP--ILTFRAPR-AQAVVGDLLELHCEALRGSSPILYWFYHEDVTLG 701
+ I S V V P I+ R PR + L L C +P + W H D +
Sbjct: 2374 AGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITW--HRDGIVL 2431
Query: 702 KISA----PSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLR 757
+ A P G +L+T SG YSC A N A S V +V + + P +
Sbjct: 2432 QEDAHTQFPERGRFLQLQALSTADSGDYSCTARN---AAGSTSVAFRVEIH-TVPTIRSG 2487
Query: 758 APGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS-----PSGGASLNLSLTAE 812
P + +V L C+A G P L + + V L RS P G + + A+
Sbjct: 2488 PPAVNVSVNQTALLPCQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ-PVLAQ 2545
Query: 813 HSGNYSCEADNGLGAQR 829
+G+Y C A N G+ R
Sbjct: 2546 DAGHYLCLASNSAGSDR 2562
Score = 92.8 bits (229), Expect = 1e-18
Identities = 213/899 (23%), Positives = 324/899 (36%), Gaps = 141/899 (15%)
Query: 34 VFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRE-----TPDNIL------EVQESGE 82
V G+ L C P+ T W+ G+ + R +PD +L + +G
Sbjct: 1266 VLDGQTAHLMCNVTGHPQPKLT-WFKD--GRPLARGDAHHISPDGVLLQVLQANLSSAGH 1322
Query: 83 YRCQAQGSPLSSPVHLDFSSASLILQAP-------------LSVFEGDSVVLRCRAKAEV 129
Y C A + H S +L AP ++V + + L C A A
Sbjct: 1323 YSCIAANAVGEKTKHFQLS----VLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFP 1378
Query: 130 TLNNTIYKN------DNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKI 183
+ N T K+ + L I +A +D G Y C E V + V++
Sbjct: 1379 SPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1438
Query: 184 QVQEPFTRP----VLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQ------ 233
+ ++ + + + +TL CE+ + P R+++D Q
Sbjct: 1439 LIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESW-----AVPPPTIRWYKDGQPVTPSS 1493
Query: 234 ---TLGLGWSLSPNFQITAMWSKDSGFYWCKAATMP------YSVISDSPRSWIQV-QIP 283
LG G L QI DSG Y C A + ++V+ P + +V
Sbjct: 1494 RLQVLGEGRLL----QIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFS 1549
Query: 284 ASHPVLTLSPEKALNF-------EGTKVTLHCETQEDSLRTLYRFYHEGVPLR---HKSV 333
A+ +L+ E E L+C+T L +Y E PL SV
Sbjct: 1550 AAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSV 1608
Query: 334 RCERGASISFSLT-TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIF 392
+ G + L EN+G Y C A N +G L +T PV L E+L+
Sbjct: 1609 -LQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVI-----LGDTEELVE 1662
Query: 393 E-----GAKVTLHCEAQRGSLPILYQFHH--EGAALERRSANSAGGVAISFSLTAEHSGN 445
E + V+L C A +P + + + R G V + + +
Sbjct: 1663 EVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAAS 1722
Query: 446 YYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQ-RGSPQIL 504
Y C A+N G K +L V VP L L A+ ++V+L C+V +P++
Sbjct: 1723 YMCVAENQAG-SAEKLFTLRVQVPPRIAGLDLEQVTAIL--NSSVSLPCDVHAHPNPEVT 1779
Query: 505 Y-------QFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSL 557
+ E L + T +GR S SG Y C A N G + ++V L
Sbjct: 1780 WYKDSQALSLGEEVFLLPGTHTLQLGRARLS------DSGMYTCEALNAAG-RDQKLVQL 1832
Query: 558 FVTVPVSRPILTLRVPRA--QAV---VGDLLELHCEAPRGSPPILYWFYHED--VTLGSS 610
V VP + + PR AV VGD L CE P + W+ V +
Sbjct: 1833 SVLVPPA----FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRT 1888
Query: 611 SAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQA 670
A GG+ G YSC+ +N + + T +L+V VP TF P+ +
Sbjct: 1889 QALRGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTVQVPP-----TFENPKTET 1942
Query: 671 ---VVGDLLELHCEALRGSSPILYWFYHE-DVTLGKISAPSGGGASFNLS-LTTEHSGIY 725
V G L L C+ +P + W V + G LS L +G Y
Sbjct: 1943 VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTY 2002
Query: 726 SCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYR 785
+C A+N R + V + P R R H G + L CEA G P
Sbjct: 2003 TCVAENTQAEARKDFVVAVLVAPRIRSSGVARE--HHVLEGQEVRLDCEA-DGQPPPDVA 2059
Query: 786 FFHEDVTLGNRSSP------SGGASLNLSLTAEHSGNYSCEADNGLGAQ-RSETVTLYI 837
+ + LG P GG+ + L A +G Y+C A N G R TV + +
Sbjct: 2060 WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLV 2118
Score = 90.1 bits (222), Expect = 9e-18
Identities = 203/898 (22%), Positives = 328/898 (36%), Gaps = 136/898 (15%)
Query: 40 VTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNIL------------EVQESGEYRCQA 87
+TL C+ P +W+ G+E + D L + Q+SG Y C A
Sbjct: 1179 LTLLCEAMGI-PPPAIRWFR---GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1234
Query: 88 QGSPLSSPVHLDFSSASLI--------LQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKND 139
+ +FS L+ L+ + V +G + L C T +K+
Sbjct: 1235 SNE--AGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDG 1292
Query: 140 NVLAFLNKRTDFH----------IPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPF 189
LA R D H + A L G Y C V T Q+
Sbjct: 1293 RPLA----RGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA----VGEKTKHFQLSVLL 1344
Query: 190 TRPVLRA---SSFQPIS---GNPVTLTCET------QLSLERSDVPLRFRFFRDDQTLGL 237
+L S+ + ++ NP++L CE ++ + P F R+ Q L
Sbjct: 1345 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAP--FEASRNIQLLPG 1402
Query: 238 GWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSW-IQVQIPAS----HPVLTLS 292
L QI +D+G Y C + + ++ +++ ++V IP S P+ +
Sbjct: 1403 THGL----QILNAQKEDAGQYTCVVT----NELGEAVKNYHVEVLIPPSISKDDPLGEVG 1454
Query: 293 PEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLT---TEN 349
++ + +TL CE+ T+ R+Y +G P+ S G + +
Sbjct: 1455 VKEVKTKVNSTLTLECESWAVPPPTI-RWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSD 1513
Query: 350 SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL----------------IFE 393
SG Y C A N G L P+ V + S+ ++ I E
Sbjct: 1514 SGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVE 1573
Query: 394 GAKVTLHCEAQRGSLPILYQFHHEG--AALERRSANSAGGVAISFSLTAEHSGNYYCTAD 451
L+C+ P L + + +A + S G V + AE++G Y C A
Sbjct: 1574 NNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS 1633
Query: 452 NGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFE-----GATVTLHCEVQRGSPQILYQ 506
N G L +T PV L E L E +TV+L C G+P
Sbjct: 1634 NEVGEDWLHYELLVLTPPV-----ILGDTEELVEEVTVNASSTVSLQCPAL-GNPVPTIS 1687
Query: 507 FYHEDMPLWSSSTPSV---GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPV 563
+ +P S V G+V + + +Y C A+N G ++ +L V VP
Sbjct: 1688 WLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG-SAEKLFTLRVQVPP 1746
Query: 564 SRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHED-VTLGSSSAPSGGEASFNL 622
I L + + A++ + L C+ P + W+ ++LG G + L
Sbjct: 1747 R--IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQL 1804
Query: 623 SLTA-EHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFR-APRA--QAV---VGDL 675
SG Y+CEA N + + LSV+VP + FR APR AV VGD
Sbjct: 1805 GRARLSDSGMYTCEALNA-AGRDQKLVQLSVLVPPA-----FRQAPRGPQDAVLVRVGDK 1858
Query: 676 LELHCEALRGSSPILYWFYH-EDVTLGKISAPSGGGASFNLS-LTTEHSGIYSCEADNGL 733
L CE P + W+ + + L + + GG + G+YSC+ N
Sbjct: 1859 AVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVA 1918
Query: 734 -EAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
EA R+ +T++V P + G L L C+ + G P + + +
Sbjct: 1919 GEAVRTFTLTVQVPPTFENP----KTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRMP 1973
Query: 793 LGNRSSP---SGGASLNLS-LTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSG 846
+ + + S G L LS L +G Y+C A+N R + V + SG
Sbjct: 1974 VESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG 2031
Score = 79.3 bits (194), Expect = 2e-14
Identities = 102/392 (26%), Positives = 160/392 (40%), Gaps = 27/392 (6%)
Query: 348 ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGS 407
E++GNY C A N G+ K L V VP PV+ P+ EG+ L C+A RGS
Sbjct: 2819 EDAGNYLCIAKNSAGSAMGKT-RLVVQVP---PVIENGLPDLSTTEGSHAFLPCKA-RGS 2873
Query: 408 LPILYQFHHEG---AALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSL 464
+ +G + E + G + +L + +G Y CTA+N G R + V L
Sbjct: 2874 PEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR-VHL 2932
Query: 465 SVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGR 524
++ V PV T + G + L C RGSP + D P+ + G
Sbjct: 2933 TILVL---PVFTTLPGDRSLRLGDRLWLRCAA-RGSPTPRIGWTVNDRPVTEGVSEQDGG 2988
Query: 525 VSFS-FSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLL 583
+ +++ SG Y C A+N G R++ VS FV V + + VG +
Sbjct: 2989 STLQRAAVSREDSGTYVCWAENRVG--RTQAVS-FVHVKEAPVLQGEAFSYLVEPVGGSI 3045
Query: 584 ELHCEAPRGSP-PILYWFYHEDVTLGSSSAPSGGEASFNLSLTA-EHSGNYSCEANNGL- 640
+L C RG P P ++W GS S + T + +G Y C A N +
Sbjct: 3046 QLDCVV-RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG 3104
Query: 641 VAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFY-HEDVT 699
VA+ + ++V S P+ GD + L C+A +P + W + +
Sbjct: 3105 VAK-----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR 3159
Query: 700 LGKISAPSGGGASFNLSLTTEHSGIYSCEADN 731
+ G+ + ++ T +G Y C A N
Sbjct: 3160 ASRRLRTLPDGSLWLENVETGDAGTYDCVAHN 3191
Score = 77.0 bits (188), Expect = 8e-14
Identities = 211/869 (24%), Positives = 301/869 (34%), Gaps = 122/869 (14%)
Query: 37 GERVTLTCKGFRFYSPQKTKWYHRYL----GKEILRETPDNILEVQESGEYRCQAQGSPL 92
G V L C SP + W+H L E ET ++L ++ GE
Sbjct: 420 GRPVALECVARGHPSPTLS-WHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA 478
Query: 93 SSPVHLDFSSASLILQAP-----------LSVFEGDSVVLRCRAKAEVTLNNTIYKNDNV 141
SSP S+ +Q P ++ G + L C+A +N
Sbjct: 479 SSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRP 538
Query: 142 LAFL------NKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLR 195
L ++ T HI H L +G + C E+ + V++ V + VL
Sbjct: 539 AEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEA--GTAGAEVEVSVHGEWAPGVLE 596
Query: 196 ASSFQPISG----NPVTLTCETQLSLERSDVPLR---------FRFFRDDQTLGLGWSLS 242
Q G + C+ + P + + + + +SL
Sbjct: 597 VPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLP 656
Query: 243 PNFQITAMWSKDSGFYWCKAATMPYSVISDSPRS-WIQVQIPASHPVLTLSPEKALNFEG 301
P QI + +D G Y C A ++ +S R ++V +P P + P E
Sbjct: 657 PPLQIEKVDLRDEGIYTCAAT----NLAGESKREVALKVLVP---PNIEPGPVNKAVLEN 709
Query: 302 TKVTLHCETQEDSLRTLYRFYHEGVP-------LRHKSVRCERGASISF--------SLT 346
VTL C GVP H+ V G ++S
Sbjct: 710 ASVTLEC-------------LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQ 756
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNL-SSPEDLIFEGAKVTLHCEAQR 405
++G+Y C A N G+ + L V VP P + L S + V L C A
Sbjct: 757 LSDAGSYRCVASNVAGSTELR-YGLRVNVP---PRITLPPSLPGPVLVNTPVRLTCNATG 812
Query: 406 GSLPILYQFHH----EGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKA 461
P L A G V S A SG Y C A + G R
Sbjct: 813 APSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDV 872
Query: 462 VSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPS 521
V L V +P P + +V L C+ P +L ++ + PL P
Sbjct: 873 V-LQVHMP---PSILGEELNVSVVANESVALECQSHAMPPPVL-SWWKDGRPL--EPRPG 925
Query: 522 VGRVSFSFSLTE------GHSGNYYCTADNGFGPQRSEV-VSLFVTVPVSRPILTLRVPR 574
V +S +L + +G+Y C A N G RSE +L V V P+ LR
Sbjct: 926 V-HLSADKALLQVDRADVWDAGHYTCEALNQAG--RSEKHYNLNVWV---APVFPLRESH 979
Query: 575 AQAV-VGDLLELHCEAPRGSP-PILYWFYHEDVTLGSSSAPSGGEASFNLSLTAE----H 628
V G L CE RG P P + W G + A L +
Sbjct: 980 TLTVREGHPTSLSCEC-RGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ 1038
Query: 629 SGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQ-AVVGD-LLELHCEALRGS 686
G Y+CE +N +V S + L V VP I R P Q +VV D + L C A
Sbjct: 1039 EGTYTCECSN-VVGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATLECNATGKP 1095
Query: 687 SPILYWFYHEDVTLGKISAP-SGGGASFNLS-LTTEHSGIYSCEADNGLEAQRSEMVTLK 744
P + W ++ G S ++ H+G YSC A+N L + L
Sbjct: 1096 PPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELS 1154
Query: 745 VAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFF--HEDVTLGNRS-SPSG 801
V VP AA+ L L CEA+ G P R+F E V+ G + +G
Sbjct: 1155 VLVPPELIGDLDPLTNITAALHSPLTLLCEAM-GIPPPAIRWFRGEEPVSPGEDTYLLAG 1213
Query: 802 GASLNLSLTAEH-SGNYSCEADNGLGAQR 829
G L ++ T E SG YSC A N G R
Sbjct: 1214 GWMLKMTQTQEQDSGLYSCLASNEAGEAR 1242
Score = 75.9 bits (185), Expect = 2e-13
Identities = 185/837 (22%), Positives = 291/837 (34%), Gaps = 141/837 (16%)
Query: 79 ESGEYRCQAQGSPLSSPVHLDFSSASLILQAP---------LSVFEGDSVVLRCRAKAEV 129
+SG Y C A S V D L + P +SV +SV L C++ A
Sbjct: 853 DSGRYSCVAV-----SAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMP 907
Query: 130 TLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKI 183
+ +K+ L + + A + D G Y C ++ + +
Sbjct: 908 PPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV 967
Query: 184 QVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPL-RFRFFRDDQTL-GLGWSL 241
V F P+ + + G+P +L+CE + VP + + +D Q L G G L
Sbjct: 968 WVAPVF--PLRESHTLTVREGHPTSLSCECR------GVPFPKISWRKDGQPLPGEGAGL 1019
Query: 242 SPNFQITAMWS------KDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEK 295
+ + G Y C+ + + V + S ++V +P P +
Sbjct: 1020 QHVSAVGRLLYLGQAQLAQEGTYTCECSNV---VGNSSQDLQLEVHVPPQIAGPREPPTQ 1076
Query: 296 ALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTE------- 348
+ TL C T+ + +G P+ GA + L +
Sbjct: 1077 VSVVQDGVATLECNATGKPPPTV-TWERDGQPV---------GAELGLQLQNQGQSLHVE 1126
Query: 349 -----NSGNYYCTADNGLGAKPSKAVSLSVTVPVS-----HPVLNLSSPEDLIFEGAKVT 398
++G Y C A+N L + + LSV VP P+ N+++ + +T
Sbjct: 1127 RAQAAHTGRYSCVAEN-LAGRAERKFELSVLVPPELIGDLDPLTNITAALH-----SPLT 1180
Query: 399 LHCEAQRGSLPILYQFHHEGAALERRSANS-AGGVAISFSLTAEH-SGNYYCTADNGFGP 456
L CEA P + F E AGG + + T E SG Y C A N G
Sbjct: 1181 LLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 1240
Query: 457 QRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWS 516
R + S+ V VP S L + +G T L C V G PQ ++ + PL
Sbjct: 1241 AR-RNFSVEVLVPPSIENEDLEEVIKV-LDGQTAHLMCNVT-GHPQPKLTWFKDGRPLAR 1297
Query: 517 SSTPSVGRVSFSFSLTEGH---SGNYYCTADNGFGPQRSEV-VSLFVTVPVSRPILTLRV 572
+ + + + +G+Y C A N G + +S+ + +
Sbjct: 1298 GDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1357
Query: 573 PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTA------ 626
V + + L CEA P + W AP EAS N+ L
Sbjct: 1358 EEVTVTVNNPISLICEALAFPSPNITWM--------KDGAPF--EASRNIQLLPGTHGLQ 1407
Query: 627 ------EHSGNYSCEANNGLVAQHSDTISLSVIVPVS----RPILTFRAPRAQAVVGDLL 676
E +G Y+C N L + + V++P S P+ + V L
Sbjct: 1408 ILNAQKEDAGQYTCVVTNEL-GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTL 1466
Query: 677 ELHCEALRGSSPILYWFYH-EDVTLGKISAPSGGGASFNLSLT-TEHSGIYSCEADNGLE 734
L CE+ P + W+ + VT G G + T SG Y C A N
Sbjct: 1467 TLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAG 1526
Query: 735 AQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRG----------SPLILY 784
+ L P+ + V G +A ++L EA G +P LY
Sbjct: 1527 EDDQDFNVLIQVPPMFQKV------GDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1580
Query: 785 -----------RFFHEDVTLGNRSSPS---GGASLNLSLT-AEHSGNYSCEADNGLG 826
++ ED L S GG L + L AE++G YSC+A N +G
Sbjct: 1581 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1637
Score = 73.2 bits (178), Expect = 1e-12
Identities = 137/528 (25%), Positives = 193/528 (36%), Gaps = 69/528 (13%)
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFE---GAKVTLHCEA 403
+ ++G Y C A N +GA KA L V VP P + + + + G V L C A
Sbjct: 374 SSDAGVYTCKASNAVGAA-EKATRLDVYVP---PTIEGAGGRPYVVKAVAGRPVALECVA 429
Query: 404 QRGSLPILYQFHHEG--AALERRSANSAGGVAISFSLTAE-HSGNYYCTADNGFGPQRSK 460
+ P L +HHEG A S G + E SG Y C A + P
Sbjct: 430 RGHPSPTL-SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASS---PAGEA 485
Query: 461 AVSLSVTVPVSHPVLTLSS-AEALTFEGATVTLHCEVQRGSPQILYQFYHEDMP---LWS 516
+ SV V V +L + T G + L C+ GSP Q+ P L
Sbjct: 486 VLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQAS-GSPVPTIQWLQNGRPAEELAG 544
Query: 517 SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQ 576
S G + HSG + C A N G +EV V+V L VP Q
Sbjct: 545 VQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE---VSVHGEWAPGVLEVPIGQ 601
Query: 577 AVVGDLLELHCEAPRGSPPILY--WFYHEDVTLGSS--------SAPSGGEASFNL---- 622
G E H P P ++ W H L P+G +++L
Sbjct: 602 YHWGX--EHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPL 659
Query: 623 ---SLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDL-LEL 678
+ G Y+C A N L + ++L V+VP + P +AV+ + + L
Sbjct: 660 QIEKVDLRDEGIYTCAATN-LAGESKREVALKVLVPPNIE----PGPVNKAVLENASVTL 714
Query: 679 HCEALRGSSPILYWFY-HEDVTLGKISAPSGGGASFNLSLTT-EHSGIYSCEADNGLEAQ 736
C A P + WF H+ V+ S G + +G Y C A N +
Sbjct: 715 ECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN-VAGS 773
Query: 737 RSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRG-SPLILYRFFHEDVTLGN 795
L+V VP R L PG V + L C A SP +++ + GN
Sbjct: 774 TELRYGLRVNVP-PRITLPPSLPGP-VLVNTPVRLTCNATGAPSPTLMW------LKDGN 825
Query: 796 RSSPSGGASLNL----------SLTAEHSGNYSCEADNGLGAQRSETV 833
SP+G L + S A SG YSC A + +G R + V
Sbjct: 826 PVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 873
Score = 69.7 bits (169), Expect = 1e-11
Identities = 113/488 (23%), Positives = 193/488 (39%), Gaps = 39/488 (7%)
Query: 162 GAYRCTGYKESCCPVSSNTVKIQVQ-EPFTRPVLRASSFQPISGNPVTLTCETQLSLERS 220
G Y C+ + V+ V + VQ P +P+ S + ++ V L CE + R
Sbjct: 2732 GRYTCSA--RNSAGVAHKHVFLTVQASPVVKPL--PSVVRAVAEEEVLLPCEAS-GIPRP 2786
Query: 221 DVPLRFRFFRDDQTLGLGWSLSPNFQITAMWS--KDSGFYWCKAATMPYSVISDSPRSWI 278
+ + + G+ + P Q+ + +D+G Y C A S + ++ +
Sbjct: 2787 TITWQKEGL--NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMG---KTRL 2841
Query: 279 QVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL---RHKSVRC 335
VQ+P PV+ EG+ L C+ + S + +G P+ K
Sbjct: 2842 VVQVP---PVIENGLPDLSTTEGSHAFLPCKAR-GSPEPNITWDKDGQPVSGAEGKFTIQ 2897
Query: 336 ERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGA 395
G + +L +++G Y CTA+N +G + + V L++ V PV + + G
Sbjct: 2898 PSGELLVKNLEGQDAGTYTCTAENAVG-RARRRVHLTILVL---PVFTTLPGDRSLRLGD 2953
Query: 396 KVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFG 455
++ L C A+ P + ++ E S G +++ E SG Y C A+N G
Sbjct: 2954 RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 3013
Query: 456 PQRSKAVSLSVTVPVSHPVLTLSSAEALTFE--GATVTLHCEVQRGSPQILYQFYHEDMP 513
R++AVS V V + A + E G ++ L C V RG P + + +P
Sbjct: 3014 --RTQAVSF---VHVKEAPVLQGEAFSYLVEPVGGSIQLDCVV-RGDPVPDIHWIKDGLP 3067
Query: 514 LWSSSTP-SVGRVSFSFSLTE-GHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLR 571
L S + S + TE +G Y C A+N G + V + V S P+ +
Sbjct: 3068 LRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVV----ILVLQSAPVFQVE 3123
Query: 572 VPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNL-SLTAEHSG 630
GD + L C+A P + W S + + S L ++ +G
Sbjct: 3124 PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAG 3183
Query: 631 NYSCEANN 638
Y C A+N
Sbjct: 3184 TYDCVAHN 3191
Score = 57.8 bits (138), Expect = 5e-08
Identities = 151/638 (23%), Positives = 239/638 (37%), Gaps = 97/638 (15%)
Query: 246 QITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVT 305
Q+ S D+G Y CKA+ +V + + + V +P + P G V
Sbjct: 368 QLGRAQSSDAGVYTCKASN---AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVA 424
Query: 306 LHCETQEDSLRTLYRFYHEGVPLRHKS-VRCERGASI--SFSLTTENSGNYYCTADNGLG 362
L C + TL ++HEG+P+ + R E S+ S +SG Y C A + G
Sbjct: 425 LECVARGHPSPTL-SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAG 483
Query: 363 AKPSKAVSLSVTVPVSHPVL---NLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGA 419
+ SV V V +L L ++ G + L C+A +P + Q+ G
Sbjct: 484 ---EAVLQYSVEVQVPPQLLVAEGLGQVTTIV--GQPLELPCQASGSPVPTI-QWLQNG- 536
Query: 420 ALERRSANSAGGVAISFSLTA--------EHSGNYYCTADNGFGPQRSKAVSLSVTVPVS 471
R A GV ++ T +HSG + C A N G ++ V +SV +
Sbjct: 537 ----RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAE-VEVSVHGEWA 591
Query: 472 HPVLTLSSAEAL--TFEGATVTLHCE--VQRG----SPQILYQFYHEDMPLWSSSTPSVG 523
VL + + ++ C+ V RG L + + LW T
Sbjct: 592 PGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPT---- 647
Query: 524 RVSFSFSLTE---------GHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPR 574
+ ++SL G Y C A N G + EV + P P P
Sbjct: 648 GIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEP-----GPV 702
Query: 575 AQAVVGDL-LELHCEAPRGSPPILYWFY-HEDVT--LGSSSAPSGGEASFNLSLTAEHSG 630
+AV+ + + L C A PP + WF H+ V+ +G + + G + ++ +G
Sbjct: 703 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSD-AG 761
Query: 631 NYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPIL 690
+Y C A+N S + + V V I + +V + L C A SP L
Sbjct: 762 SYRCVASN---VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTL 818
Query: 691 YWFYHEDVTLGKISAPSG--------GGASFNL-SLTTEHSGIYSCEADNGLEAQRSEMV 741
W G +P+G GG L S SG YSC A + + R ++V
Sbjct: 819 MWLKD-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 873
Query: 742 TLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPSG 801
L+V +P P + + + L C++ P +L + +D G P
Sbjct: 874 -LQVHMP---PSILGEELNVSVVANESVALECQSHAMPPPVL--SWWKD---GRPLEPRP 924
Query: 802 GASLNLS--------LTAEHSGNYSCEADNGLGAQRSE 831
G L+ +G+Y+CEA N G RSE
Sbjct: 925 GVHLSADKALLQVDRADVWDAGHYTCEALNQAG--RSE 960
Score = 40.8 bits (94), Expect = 0.006
Identities = 72/314 (22%), Positives = 119/314 (37%), Gaps = 40/314 (12%)
Query: 75 LEVQESGEYRCQAQGSP--LSSPVHLDFSSASLILQAP--LSVFEGDSVVLRCRAKAEVT 130
LE Q++G Y C A+ + VHL + P S+ GD + LRC A+ T
Sbjct: 2907 LEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPT 2966
Query: 131 LNNTIYKNDNVLAFLNKRTD----FHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQ 186
ND + D +D+G Y C + E+ + + V+
Sbjct: 2967 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC--WAENRVGRTQAVSFVHVK 3024
Query: 187 EPFTRPVLRASSF----QPISGNPVTLTCETQ------LSLERSDVPLRFRFFRDDQTLG 236
E PVL+ +F +P+ G+ + L C + + + +PLR R G
Sbjct: 3025 EA---PVLQGEAFSYLVEPVGGS-IQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG 3080
Query: 237 LGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKA 296
+ I D+G Y C A + + + S PV + P+
Sbjct: 3081 -------SLTIHRTERDDAGRYQCLAEN------EMGVAKKVVILVLQSAPVFQVEPQDM 3127
Query: 297 LNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLR-HKSVRCERGASISF-SLTTENSGNYY 354
G V L C+ + T+ + G PLR + +R S+ ++ T ++G Y
Sbjct: 3128 TVRSGDDVALRCQATGEPTPTI-EWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 3186
Query: 355 CTADNGLGAKPSKA 368
C A N LG+ ++A
Sbjct: 3187 CVAHNLLGSATARA 3200
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 107 bits (266), Expect = 7e-23
Identities = 197/818 (24%), Positives = 319/818 (38%), Gaps = 121/818 (14%)
Query: 74 ILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSV-----------FEGDSVVLR 122
+L V+++G Y C A+ SP S + +QAP ++ +VL
Sbjct: 3548 VLRVRDAGLYTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLE 3602
Query: 123 CRAKAEVTLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPV 176
C +AE T +++ VL F + + D+G Y CT +
Sbjct: 3603 CSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA---- 3658
Query: 177 SSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSL---ERSDVPLRFRFFRDDQ 233
S +V +V E T P +R SG P Q +L + VP +R D+
Sbjct: 3659 GSTSVAFRV-EIHTVPTIR-------SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDR 3710
Query: 234 T----LGLGWSLSP--NFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHP 287
+ + P + +I + ++D+G Y C A+ S SD ++V P P
Sbjct: 3711 VPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN---SAGSDRQGRDLRVLEP---P 3764
Query: 288 VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGA-----SIS 342
+ SP T L CE S + L ++ +G L R ++GA S +
Sbjct: 3765 AIAPSPSNLTLTAHTPALLPCEAS-GSPKPLVVWWKDGQKL---DFRLQQGAYRLLPSNA 3820
Query: 343 FSLTT---ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTL 399
LT ++S + C N +G + + ++V VP P + + + A V L
Sbjct: 3821 LLLTAPGPQDSAQFECVVSNEVG-EAHRLYQVTVHVP---PTIADDQTDFTVTMMAPVVL 3876
Query: 400 HCEAQRGSLPILYQFHHEGAALERRSA----NSAGGVAISFSLTAEHSGNYYCTADNGFG 455
C + P + + GA L R + + +G + I +L H+G Y C+A N G
Sbjct: 3877 TCHSTGIPAPTV-SWSKAGAQLGARGSGYRVSPSGALEIGQALPI-HAGRYTCSARNSAG 3934
Query: 456 PQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLW 515
PV P+ ++ A A V L CE G P+ + E + +
Sbjct: 3935 VAHKHVFLTVQASPVVKPLPSVVRAVA----EEEVLLPCEAS-GIPRPTITWQKEGLNVA 3989
Query: 516 SSSTPSV---GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRV 572
+ + V G++ + + E +GNY C A N G + L V VP P++ +
Sbjct: 3990 TGVSTQVLPGGQLRIAHASPED-AGNYLCIAKNSAGSAMGKT-RLVVQVP---PVIENGL 4044
Query: 573 PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAP-SGGEASFNL--------- 622
P G L C+A RGSP ++T P SG E F +
Sbjct: 4045 PDLSTTEGSHAFLPCKA-RGSP-------EPNITWDKDGQPVSGAEGKFTIQPSGELLVK 4096
Query: 623 SLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA 682
+L + +G Y+C A N V + + L+++V P+ T +GD L L C A
Sbjct: 4097 NLEGQDAGTYTCTAENA-VGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWLRCAA 4152
Query: 683 LRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGL-EAQRSEMV 741
+P + W ++ +S GG +++ E SG Y C A+N + Q V
Sbjct: 4153 RGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFV 4212
Query: 742 TLKVAVPVSRPVLTLRA-PGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPS 800
+K A PVL A VG ++L C +RG P+ + + + L R S
Sbjct: 4213 HVKEA-----PVLQGEAFSYLVEPVGGSIQLDC-VVRGDPVPDIHWIKDGLPL--RGSHL 4264
Query: 801 GGASLNLSLT-----AEHSGNYSCEADNGLGAQRSETV 833
N SLT + +G Y C A+N +G + +
Sbjct: 4265 RHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVI 4302
Score = 106 bits (264), Expect = 1e-22
Identities = 207/857 (24%), Positives = 326/857 (38%), Gaps = 83/857 (9%)
Query: 19 RTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRY----LGKEILRETPDNI 74
+ P I L T V+L C +P+ T WY LG+E+ +
Sbjct: 2934 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVT-WYKDSQALSLGEEVFLLPGTHT 2992
Query: 75 LEV-----QESGEYRCQAQGSP--------LSSPVHLDFSSASLILQAPLSVFEGDSVVL 121
L++ +SG Y C+A + LS V F A Q + V GD VL
Sbjct: 2993 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVL 3052
Query: 122 RCRAKAEVTLNNTIYKNDNVLAFLNKRTD-------FHIPHACLKDNGAYRCTGYKESCC 174
C A T YK+ L L +RT I A + D G Y C +
Sbjct: 3053 SCETDALPEPTVTWYKDGQPLV-LAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE 3111
Query: 175 PVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQT 234
V + T+ +QV F P + + ++G+P+ LTC+ + L+ R +
Sbjct: 3112 AVRTFTLTVQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA 3169
Query: 235 LGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPE 294
+ S Q++ + +G Y C A + +++ + ++ + A +
Sbjct: 3170 VHGVVSRGGRLQLSRLQPAQAGTYTCVAE----NTQAEARKDFVVAVLVAPRIRSSGVAR 3225
Query: 295 KALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL-----RHKSVRCERGASISFSLTTEN 349
+ EG +V L CE + + +G PL H + G+ + L +
Sbjct: 3226 EHHVLEGQEVRLDCEADGQPPPDV-AWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASD 3284
Query: 350 SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLP 409
+G Y C A N G + ++ +++V VP + S + G VT+ C RGS P
Sbjct: 3285 AGAYTCVAHNPAG-EDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPV-RGSPP 3342
Query: 410 ILYQFHHEGAAL---ERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSV 466
I + +G L +R + +G + +G + C A + G + +L V
Sbjct: 3343 IHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG-VADRNFTLQV 3401
Query: 467 TV-PVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRV 525
V PV PV + + + G+ V L CE RG P L + + PL S S +
Sbjct: 3402 QVPPVLEPVEFQN--DVVVVRGSLVELPCEA-RGVPLPLVSWMKDGEPLLSQSLEQGPSL 3458
Query: 526 SFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVV-GDLLE 584
++ G SG Y C A + G R +TV I P ++ G +E
Sbjct: 3459 QLE-AVGAGDSGTYSCVAVSEAGEARRH---FQLTVMEPPHIEDSGQPTELSLTPGAPME 3514
Query: 585 LHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQH 644
L C+A P + W H+D G + + L +G Y+C L
Sbjct: 3515 LLCDAQGTPQPNITW--HKD---GQALTRLENNSRATRVLRVRDAGLYTC-----LAESP 3564
Query: 645 SDTISLSVIVPVSRP--ILTFRAPR-AQAVVGDLLELHCEALRGSSPILYWFYHEDVTLG 701
+ I S V V P I+ R PR + L L C +P + W H D +
Sbjct: 3565 AGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITW--HRDGIVL 3622
Query: 702 KISA----PSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLR 757
+ A P G +L+T SG YSC A N A S V +V + + P +
Sbjct: 3623 QEDAHTQFPERGRFLQLQALSTADSGDYSCTARN---AAGSTSVAFRVEIH-TVPTIRSG 3678
Query: 758 APGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS-----PSGGASLNLSLTAE 812
P + +V L C+A G P L + + V L RS P G + + A+
Sbjct: 3679 PPAVNVSVNQTALLPCQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ-PVLAQ 3736
Query: 813 HSGNYSCEADNGLGAQR 829
+G+Y C A N G+ R
Sbjct: 3737 DAGHYLCLASNSAGSDR 3753
Score = 94.0 bits (232), Expect = 6e-19
Identities = 228/981 (23%), Positives = 344/981 (35%), Gaps = 179/981 (18%)
Query: 16 QFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYH--RYLGKEILR--ETP 71
Q T P + P TV GE L+C+ +P W R L R +
Sbjct: 510 QIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLG-EAPYNLTWVRDWRVLPASTGRVAQLA 568
Query: 72 DNILEVQ-----ESGEYRC---QAQGSPLSSPVHLDFSSASLILQAPLSVF-EGDSVVLR 122
D LE+ + G Y+C A G +S L + + + F +G V +
Sbjct: 569 DLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVS 628
Query: 123 CRAKAEVTLNNTIYKNDNVLA-----FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVS 177
C A T + + + L ++ + I +D G Y C E
Sbjct: 629 CSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNE--VGTD 686
Query: 178 SNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRD--DQTL 235
TV + +P + + A + G L CE P R ++R + L
Sbjct: 687 QETVTLYYTDPPSVSAVNAVVLVAV-GEEAVLVCEAS-----GVPPPRVIWYRGGLEMIL 740
Query: 236 GLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASH-PVLTLSPE 294
S S +I A +D+G Y C+A +++ + ++Q+ H P LT P
Sbjct: 741 APEGSSSGKLRIPAAQERDAGTYTCRA-------VNELGDASAEIQLAVGHAPQLTELPR 793
Query: 295 KALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLR--------HKSVRCERGASISFSLT 346
G L C T+ +G PL +S + + G S+
Sbjct: 794 DVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVA 853
Query: 347 TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRG 406
E+ Y C A N G ++A + + P + S+P + EG V+L C G
Sbjct: 854 PEDQAPYVCEARNVFGKVQAEA--RLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAG 911
Query: 407 SLPILYQFHHEGAAL---ERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVS 463
+ +G L R S + G + + +L EH+G Y C A N G Q + V
Sbjct: 912 RPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQ-EHAGRYSCVATNTAGSQH-RDVE 969
Query: 464 LSVTVPVS-HPVLTLSSAEALTFEGATVTL--------------------------HCEV 496
L V VP HP T +T EG +L H V
Sbjct: 970 LVVQVPPRIHPTAT----HHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNV 1025
Query: 497 QRGSPQILYQFYHEDMPLWSSSTP------------SVGRVSFSFSLTE----------- 533
+ ++ Q +D + + SV R++ S + E
Sbjct: 1026 SKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLR 1085
Query: 534 ------GHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRA-QAVVGDLLELH 586
G SG+Y CTA N G V P +P PR + +VG+ L+L+
Sbjct: 1086 LAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQP-----GPRVLKVLVGEALDLN 1140
Query: 587 CEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSD 646
C A P L W +D + P G + ++ +G Y CEA+N +
Sbjct: 1141 CVAEGNPEPQLSW--SKDGVVLQGRGPQG--SVHFAAIRTSDAGRYRCEASNS-AGVDAW 1195
Query: 647 TISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAP 706
+ L V+ P + + V G+ L C A P + W G S P
Sbjct: 1196 EVELRVLEPPHWG-ADETSGLLERVAGENASLPCPARGTPKPQVTW------RKGPSSEP 1248
Query: 707 SGG---------GASFNLSLTTEHSGIYSCEADN--GLEAQRSEMVTLKVAVPVSRPVLT 755
G G+ F S++ SG Y C+A N G ++R+++V V VP S
Sbjct: 1249 LHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLV---VYVPPS----- 1300
Query: 756 LRAPGTHAAV----GDLLELHCEA---------------LRGSPL--ILYRFFHEDVTLG 794
+R G A V G L L C+A L G PL Y + +G
Sbjct: 1301 IREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVG 1360
Query: 795 NRSSPSGGASLNLSLTAE-HSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVA 853
G SL+ E SG YSC A+N G + + L +T P + A
Sbjct: 1361 GHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLT--------PPSVLGA 1412
Query: 854 GGLLSIAGLAAGALLLYCWLS 874
G + GLA + L CW S
Sbjct: 1413 GAAQEVLGLAGADVELQCWTS 1433
Score = 92.8 bits (229), Expect = 1e-18
Identities = 213/899 (23%), Positives = 324/899 (36%), Gaps = 141/899 (15%)
Query: 34 VFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRE-----TPDNIL------EVQESGE 82
V G+ L C P+ T W+ G+ + R +PD +L + +G
Sbjct: 2457 VLDGQTAHLMCNVTGHPQPKLT-WFKD--GRPLARGDAHHISPDGVLLQVLQANLSSAGH 2513
Query: 83 YRCQAQGSPLSSPVHLDFSSASLILQAP-------------LSVFEGDSVVLRCRAKAEV 129
Y C A + H S +L AP ++V + + L C A A
Sbjct: 2514 YSCIAANAVGEKTKHFQLS----VLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFP 2569
Query: 130 TLNNTIYKN------DNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKI 183
+ N T K+ + L I +A +D G Y C E V + V++
Sbjct: 2570 SPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 2629
Query: 184 QVQEPFTRP----VLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQ------ 233
+ ++ + + + +TL CE+ + P R+++D Q
Sbjct: 2630 LIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESW-----AVPPPTIRWYKDGQPVTPSS 2684
Query: 234 ---TLGLGWSLSPNFQITAMWSKDSGFYWCKAATMP------YSVISDSPRSWIQV-QIP 283
LG G L QI DSG Y C A + ++V+ P + +V
Sbjct: 2685 RLQVLGEGRLL----QIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFS 2740
Query: 284 ASHPVLTLSPEKALNF-------EGTKVTLHCETQEDSLRTLYRFYHEGVPLR---HKSV 333
A+ +L+ E E L+C+T L +Y E PL SV
Sbjct: 2741 AAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSV 2799
Query: 334 RCERGASISFSLT-TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIF 392
+ G + L EN+G Y C A N +G L +T PV L E+L+
Sbjct: 2800 -LQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVI-----LGDTEELVE 2853
Query: 393 E-----GAKVTLHCEAQRGSLPILYQFHH--EGAALERRSANSAGGVAISFSLTAEHSGN 445
E + V+L C A +P + + + R G V + + +
Sbjct: 2854 EVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAAS 2913
Query: 446 YYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQ-RGSPQIL 504
Y C A+N G K +L V VP L L A+ ++V+L C+V +P++
Sbjct: 2914 YMCVAENQAG-SAEKLFTLRVQVPPRIAGLDLEQVTAIL--NSSVSLPCDVHAHPNPEVT 2970
Query: 505 Y-------QFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSL 557
+ E L + T +GR S SG Y C A N G + ++V L
Sbjct: 2971 WYKDSQALSLGEEVFLLPGTHTLQLGRARLS------DSGMYTCEALNAAG-RDQKLVQL 3023
Query: 558 FVTVPVSRPILTLRVPRA--QAV---VGDLLELHCEAPRGSPPILYWFYHED--VTLGSS 610
V VP + + PR AV VGD L CE P + W+ V +
Sbjct: 3024 SVLVPPA----FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRT 3079
Query: 611 SAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQA 670
A GG+ G YSC+ +N + + T +L+V VP TF P+ +
Sbjct: 3080 QALRGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTVQVPP-----TFENPKTET 3133
Query: 671 ---VVGDLLELHCEALRGSSPILYWFYHE-DVTLGKISAPSGGGASFNLS-LTTEHSGIY 725
V G L L C+ +P + W V + G LS L +G Y
Sbjct: 3134 VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTY 3193
Query: 726 SCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYR 785
+C A+N R + V + P R R H G + L CEA G P
Sbjct: 3194 TCVAENTQAEARKDFVVAVLVAPRIRSSGVARE--HHVLEGQEVRLDCEA-DGQPPPDVA 3250
Query: 786 FFHEDVTLGNRSSP------SGGASLNLSLTAEHSGNYSCEADNGLGAQ-RSETVTLYI 837
+ + LG P GG+ + L A +G Y+C A N G R TV + +
Sbjct: 3251 WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLV 3309
Score = 90.1 bits (222), Expect = 9e-18
Identities = 203/898 (22%), Positives = 328/898 (36%), Gaps = 136/898 (15%)
Query: 40 VTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNIL------------EVQESGEYRCQA 87
+TL C+ P +W+ G+E + D L + Q+SG Y C A
Sbjct: 2370 LTLLCEAMGI-PPPAIRWFR---GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 2425
Query: 88 QGSPLSSPVHLDFSSASLI--------LQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKND 139
+ +FS L+ L+ + V +G + L C T +K+
Sbjct: 2426 SNE--AGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDG 2483
Query: 140 NVLAFLNKRTDFH----------IPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPF 189
LA R D H + A L G Y C V T Q+
Sbjct: 2484 RPLA----RGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA----VGEKTKHFQLSVLL 2535
Query: 190 TRPVLRA---SSFQPIS---GNPVTLTCET------QLSLERSDVPLRFRFFRDDQTLGL 237
+L S+ + ++ NP++L CE ++ + P F R+ Q L
Sbjct: 2536 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAP--FEASRNIQLLPG 2593
Query: 238 GWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSW-IQVQIPAS----HPVLTLS 292
L QI +D+G Y C + + ++ +++ ++V IP S P+ +
Sbjct: 2594 THGL----QILNAQKEDAGQYTCVVT----NELGEAVKNYHVEVLIPPSISKDDPLGEVG 2645
Query: 293 PEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLT---TEN 349
++ + +TL CE+ T+ R+Y +G P+ S G + +
Sbjct: 2646 VKEVKTKVNSTLTLECESWAVPPPTI-RWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSD 2704
Query: 350 SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL----------------IFE 393
SG Y C A N G L P+ V + S+ ++ I E
Sbjct: 2705 SGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVE 2764
Query: 394 GAKVTLHCEAQRGSLPILYQFHHEG--AALERRSANSAGGVAISFSLTAEHSGNYYCTAD 451
L+C+ P L + + +A + S G V + AE++G Y C A
Sbjct: 2765 NNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS 2824
Query: 452 NGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFE-----GATVTLHCEVQRGSPQILYQ 506
N G L +T PV L E L E +TV+L C G+P
Sbjct: 2825 NEVGEDWLHYELLVLTPPV-----ILGDTEELVEEVTVNASSTVSLQCPAL-GNPVPTIS 2878
Query: 507 FYHEDMPLWSSSTPSV---GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPV 563
+ +P S V G+V + + +Y C A+N G ++ +L V VP
Sbjct: 2879 WLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG-SAEKLFTLRVQVPP 2937
Query: 564 SRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHED-VTLGSSSAPSGGEASFNL 622
I L + + A++ + L C+ P + W+ ++LG G + L
Sbjct: 2938 R--IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQL 2995
Query: 623 SLTA-EHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFR-APRA--QAV---VGDL 675
SG Y+CEA N + + LSV+VP + FR APR AV VGD
Sbjct: 2996 GRARLSDSGMYTCEALNA-AGRDQKLVQLSVLVPPA-----FRQAPRGPQDAVLVRVGDK 3049
Query: 676 LELHCEALRGSSPILYWFYH-EDVTLGKISAPSGGGASFNLS-LTTEHSGIYSCEADNGL 733
L CE P + W+ + + L + + GG + G+YSC+ N
Sbjct: 3050 AVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVA 3109
Query: 734 -EAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
EA R+ +T++V P + G L L C+ + G P + + +
Sbjct: 3110 GEAVRTFTLTVQVPPTFENP----KTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRMP 3164
Query: 793 LGNRSSP---SGGASLNLS-LTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSG 846
+ + + S G L LS L +G Y+C A+N R + V + SG
Sbjct: 3165 VESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG 3222
Score = 84.0 bits (206), Expect = 6e-16
Identities = 127/498 (25%), Positives = 185/498 (37%), Gaps = 39/498 (7%)
Query: 351 GNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPI 410
G Y CTA + G +KA + VT P P + +P + G L C G P
Sbjct: 492 GTYECTAVSRAGTGRAKA-QIVVTDP---PPQLVPAPNVTVSPGETAVLSCRVL-GEAPY 546
Query: 411 LYQFHHEGAALERRSANSAGGVAISFSLTA---EHSGNYYCTADNGFGPQRSKAVSLSVT 467
+ + L + A +S ++ G Y C A N G R+ SV
Sbjct: 547 NLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-----SVW 601
Query: 468 VPVSH-PVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVS 526
+ V P +++ ++ +G V + C G P + E L S V
Sbjct: 602 LLVREAPQVSIHTSSQHFSQGVEVKVSCSAS-GYPTPHISWSRESQALQEDSRIHVDAQG 660
Query: 527 FSF--SLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLE 584
+ +GNY C A N G + E V+L+ T P S + V A VG+
Sbjct: 661 TLIIQGVAPEDAGNYSCQATNEVGTDQ-ETVTLYYTDPPSVSAVNAVVLVA---VGEEAV 716
Query: 585 LHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQH 644
L CEA PP + W+ + + S G+ + + +G Y+C A N L
Sbjct: 717 LVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERD-AGTYTCRAVNEL-GDA 774
Query: 645 SDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLG-KI 703
S I L+V P LT +G L C A P + W + LG ++
Sbjct: 775 SAEIQLAV---GHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRL 831
Query: 704 SAPSGG-------GASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTL 756
A G G F S+ E Y CEA N ++E + + P +
Sbjct: 832 GAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAE--ARLIVTGHAPPQIAS 889
Query: 757 RAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTL--GNRSSPSGGASLNLSLTA-EH 813
AP G + L C L G PL + + L G+R S SL+L EH
Sbjct: 890 SAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEH 949
Query: 814 SGNYSCEADNGLGAQRSE 831
+G YSC A N G+Q +
Sbjct: 950 AGRYSCVATNTAGSQHRD 967
Score = 80.5 bits (197), Expect = 7e-15
Identities = 220/899 (24%), Positives = 319/899 (35%), Gaps = 157/899 (17%)
Query: 37 GERVTLTCKGFRFYSPQKTKW--------YHRYLGKEILRETPDNILEVQ--ESGEYRCQ 86
GE +L C PQ T W H G +L E + V +SG+Y CQ
Sbjct: 1221 GENASLPCPARGTPKPQVT-WRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQ 1279
Query: 87 AQGSPLSSPVHLDFSSASLILQAPLSVFE-----------GDSVVLRCRAKAEVTLNNTI 135
A ++ V A L++ P S+ E G S+ L C A + +
Sbjct: 1280 A-----TNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANG-FPVPEIV 1333
Query: 136 YKNDNVLA----------------------FLNKRTDFHIPHACLKDNGAYRCTGYKESC 173
+ D L L++ H P D+G Y C E+
Sbjct: 1334 WLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRA--ENQ 1391
Query: 174 CPVSSNTVKIQVQEPFTRPVLRASSFQPI---SGNPVTLTCETQLSLERSDVPL-RFRFF 229
+ + V P + VL A + Q + +G V L C T S VP + +
Sbjct: 1392 AGTAQRDFHLLVLTPPS--VLGAGAAQEVLGLAGADVELQCWT------SGVPTPQVEWT 1443
Query: 230 RDDQTLGLGWSLSPNFQ---------ITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQV 280
+D Q + G P+ Q IT D G Y C A +S R + Q+
Sbjct: 1444 KDRQPVLPG---GPHLQVQEDGQVLRITGSHVGDEGRYQCVA----FSPAGQQARDF-QL 1495
Query: 281 QIPASHPVLTLSPE--KALNFEGTKVTLHCETQEDSLRTLYRFYHEG--VPLRHKSVRCE 336
++ A P + S E + E V L CE + + ++ +G +P K V
Sbjct: 1496 RVHAP-PTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNI-TWFKDGALLPTSTKVVYTR 1553
Query: 337 RGASISFSLT-TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFE-- 393
G + + ++G Y C A N +GA KA L V VP P + + + +
Sbjct: 1554 GGRQLQLGRAQSSDAGVYTCKASNAVGAA-EKATRLDVYVP---PTIEGAGGRPYVVKAV 1609
Query: 394 -GAKVTLHCEAQRGSLPILYQFHHEG--AALERRSANSAGGVAISFSLTAE-HSGNYYCT 449
G V L C A+ P L +HHEG A S G + E SG Y C
Sbjct: 1610 AGRPVALECVARGHPSPTL-SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV 1668
Query: 450 ADNGFGPQRSKAVSLSVTVPVSHPVLTLSS-AEALTFEGATVTLHCEVQRGSPQILYQFY 508
A + P + SV V V +L + T G + L C+ GSP Q+
Sbjct: 1669 ASS---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQAS-GSPVPTIQWL 1724
Query: 509 HEDMP---LWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSR 565
P L S G + HSG + C A N G +EV V+V
Sbjct: 1725 QNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE---VSVHGEW 1781
Query: 566 PILTLRVPRAQAVVGDLLELHCEAPRGSPPILY--WFYHEDVTLGSS--------SAPSG 615
L VP Q G E H P P ++ W H L P+G
Sbjct: 1782 APGVLEVPIGQYHWGX--EHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTG 1839
Query: 616 GEASFNL-------SLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRA 668
+++L + G Y+C A N L + ++L V+VP + P
Sbjct: 1840 IPVAYSLPPPLQIEKVDLRDEGIYTCAATN-LAGESKREVALKVLVPPNIE----PGPVN 1894
Query: 669 QAVVGDL-LELHCEALRGSSPILYWFY-HEDVTLGKISAPSGGGASFNLSLTT-EHSGIY 725
+AV+ + + L C A P + WF H+ V+ S G + +G Y
Sbjct: 1895 KAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSY 1954
Query: 726 SCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRG-SPLILY 784
C A N + L+V VP R L PG V + L C A SP +++
Sbjct: 1955 RCVASN-VAGSTELRYGLRVNVP-PRITLPPSLPGP-VLVNTPVRLTCNATGAPSPTLMW 2011
Query: 785 RFFHEDVTLGNRSSPSGGASLNL----------SLTAEHSGNYSCEADNGLGAQRSETV 833
+ GN SP+G L + S A SG YSC A + +G R + V
Sbjct: 2012 ------LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 2064
Score = 80.1 bits (196), Expect = 9e-15
Identities = 150/652 (23%), Positives = 241/652 (36%), Gaps = 62/652 (9%)
Query: 206 PVTLTCETQLSLERSDVPLRFRFFRDDQTLG----LGWSLSPNFQITAMWSKDSGFYWCK 261
P+ ++C +L P R + R + LG S + +++I + G Y C
Sbjct: 443 PLLVSCSVHSAL-----PFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECT 497
Query: 262 AATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRF 321
A + + + R+ Q+ + P L +P ++ G L C ++ L +
Sbjct: 498 AVSR-----AGTGRAKAQIVVTDPPPQLVPAPNVTVS-PGETAVLSCRVLGEAPYNL-TW 550
Query: 322 YHEGVPLRHKSVRCERGASISFSLT---TENSGNYYCTADNGLGAKPSKAVSLSVTVPVS 378
+ L + R + A +S ++ + G Y C A N G + SV + V
Sbjct: 551 VRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-----SVWLLVR 605
Query: 379 H-PVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSAN--SAGGVAIS 435
P +++ + +G +V + C A P + + E AL+ S A G I
Sbjct: 606 EAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHI-SWSRESQALQEDSRIHVDAQGTLII 664
Query: 436 FSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCE 495
+ E +GNY C A N G + + V+L T P P ++ +A L G L CE
Sbjct: 665 QGVAPEDAGNYSCQATNEVGTDQ-ETVTLYYTDP---PSVSAVNAVVLVAVGEEAVLVCE 720
Query: 496 VQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVV 555
P + + + + S G++ + E +G Y C A N G +E+
Sbjct: 721 ASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIP-AAQERDAGTYTCRAVNELGDASAEI- 778
Query: 556 SLFVTVPVSRPILTLRVPRAQAV-VGDLLELHCEAPRGSPPILYWFYHEDVTLG------ 608
+ V +PR V +G L C A PP + W + LG
Sbjct: 779 ----QLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAG 834
Query: 609 ---SSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRA 665
S P G F S+ E Y CEA N ++ + ++ + P + A
Sbjct: 835 RGSRSRQPDSGVLFFE-SVAPEDQAPYVCEARNVFGKVQAE--ARLIVTGHAPPQIASSA 891
Query: 666 PRAQAVVGDLLELHCEALRGSS-PILYWFYH-EDVTLGKISAPSGGGASFNLSLTTEHSG 723
P + + G + L C L G P +W + G + G+ EH+G
Sbjct: 892 PTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAG 951
Query: 724 IYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLIL 783
YSC A N +Q + V L V VP P + A G L C A G P
Sbjct: 952 RYSCVATNTAGSQHRD-VELVVQVP---PRIHPTATHHITNEGVPASLPCVA-SGVPAPT 1006
Query: 784 YRFFHEDVTLGNR----SSPSGGASLNLSLTAEHSGNYSCEADNGLGAQRSE 831
+ E L +R + G L +A+ +G Y C A N +G E
Sbjct: 1007 ITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQE 1058
Score = 79.3 bits (194), Expect = 2e-14
Identities = 102/392 (26%), Positives = 160/392 (40%), Gaps = 27/392 (6%)
Query: 348 ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGS 407
E++GNY C A N G+ K L V VP PV+ P+ EG+ L C+A RGS
Sbjct: 4010 EDAGNYLCIAKNSAGSAMGKT-RLVVQVP---PVIENGLPDLSTTEGSHAFLPCKA-RGS 4064
Query: 408 LPILYQFHHEG---AALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSL 464
+ +G + E + G + +L + +G Y CTA+N G R + V L
Sbjct: 4065 PEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR-VHL 4123
Query: 465 SVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGR 524
++ V PV T + G + L C RGSP + D P+ + G
Sbjct: 4124 TILVL---PVFTTLPGDRSLRLGDRLWLRCAA-RGSPTPRIGWTVNDRPVTEGVSEQDGG 4179
Query: 525 VSFS-FSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLL 583
+ +++ SG Y C A+N G R++ VS FV V + + VG +
Sbjct: 4180 STLQRAAVSREDSGTYVCWAENRVG--RTQAVS-FVHVKEAPVLQGEAFSYLVEPVGGSI 4236
Query: 584 ELHCEAPRGSP-PILYWFYHEDVTLGSSSAPSGGEASFNLSLTA-EHSGNYSCEANNGL- 640
+L C RG P P ++W GS S + T + +G Y C A N +
Sbjct: 4237 QLDCVV-RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG 4295
Query: 641 VAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFY-HEDVT 699
VA+ + ++V S P+ GD + L C+A +P + W + +
Sbjct: 4296 VAK-----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR 4350
Query: 700 LGKISAPSGGGASFNLSLTTEHSGIYSCEADN 731
+ G+ + ++ T +G Y C A N
Sbjct: 4351 ASRRLRTLPDGSLWLENVETGDAGTYDCVAHN 4382
Score = 76.6 bits (187), Expect = 1e-13
Identities = 134/520 (25%), Positives = 188/520 (36%), Gaps = 84/520 (16%)
Query: 349 NSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSL 408
+ G Y C A N L + + V+L V VP P + + E A VTL C A
Sbjct: 1859 DEGIYTCAATN-LAGESKREVALKVLVP---PNIEPGPVNKAVLENASVTLECLASGVPP 1914
Query: 409 PILYQF--HHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSV 466
P + F H ++ + + G V +G+Y C A N G + L V
Sbjct: 1915 PDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELR-YGLRV 1973
Query: 467 TVPVSHPVLTLS-SAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSV--- 522
VP P +TL S V L C G+P + + P+ + TP +
Sbjct: 1974 NVP---PRITLPPSLPGPVLVNTPVRLTCNAT-GAPSPTLMWLKDGNPVSPAGTPGLQVF 2029
Query: 523 --GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVG 580
GRV S SG Y C A + G R +VV L V +P P + V
Sbjct: 2030 PGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV-LQVHMP---PSILGEELNVSVVAN 2085
Query: 581 DLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHS----------- 629
+ + L C++ PP+L W+ G P G + L+A+ +
Sbjct: 2086 ESVALECQSHAMPPPVLSWWKD-----GRPLEPRPG-----VHLSADKALLQVDRADVWD 2135
Query: 630 -GNYSCEANNGLVAQHSDT-ISLSVIVPVSRPILTFRAPRAQAV-VGDLLELHCEALRGS 686
G+Y+CEA N A HS+ +L+V V P+ R V G L CE
Sbjct: 2136 AGHYTCEALNQ--AGHSEKHYNLNVWVA---PVFPLRESHTLTVREGHPTSLSCECRGVP 2190
Query: 687 SPILYW------FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEM 740
P + W E L +SA G + G Y+CE N + S+
Sbjct: 2191 FPKISWRKDGQPLPGEGAGLQHVSAV--GRLLYLGQAQLAQEGTYTCECSN-VVGNSSQD 2247
Query: 741 VTLKVAVPVSRPVLTLRAPGTHAAV--GDLLELHCEALRGSPLILYRFFHEDVTLGNRSS 798
+ L+V VP + R P T +V + L C A P R
Sbjct: 2248 LQLEVHVPPQ--IAGPREPPTQVSVVQDGVATLECNATGKPP---------PTVTWERDG 2296
Query: 799 PSGGASLNLSLT------------AEHSGNYSCEADNGLG 826
GA L L L A H+G YSC A+N G
Sbjct: 2297 QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAG 2336
Score = 75.9 bits (185), Expect = 2e-13
Identities = 185/837 (22%), Positives = 291/837 (34%), Gaps = 141/837 (16%)
Query: 79 ESGEYRCQAQGSPLSSPVHLDFSSASLILQAP---------LSVFEGDSVVLRCRAKAEV 129
+SG Y C A S V D L + P +SV +SV L C++ A
Sbjct: 2044 DSGRYSCVAV-----SAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMP 2098
Query: 130 TLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKI 183
+ +K+ L + + A + D G Y C ++ + +
Sbjct: 2099 PPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 2158
Query: 184 QVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPL-RFRFFRDDQTL-GLGWSL 241
V F P+ + + G+P +L+CE + VP + + +D Q L G G L
Sbjct: 2159 WVAPVF--PLRESHTLTVREGHPTSLSCECR------GVPFPKISWRKDGQPLPGEGAGL 2210
Query: 242 SPNFQITAMWS------KDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEK 295
+ + G Y C+ + + V + S ++V +P P +
Sbjct: 2211 QHVSAVGRLLYLGQAQLAQEGTYTCECSNV---VGNSSQDLQLEVHVPPQIAGPREPPTQ 2267
Query: 296 ALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTE------- 348
+ TL C T+ + +G P+ GA + L +
Sbjct: 2268 VSVVQDGVATLECNATGKPPPTV-TWERDGQPV---------GAELGLQLQNQGQSLHVE 2317
Query: 349 -----NSGNYYCTADNGLGAKPSKAVSLSVTVPVS-----HPVLNLSSPEDLIFEGAKVT 398
++G Y C A+N L + + LSV VP P+ N+++ + +T
Sbjct: 2318 RAQAAHTGRYSCVAEN-LAGRAERKFELSVLVPPELIGDLDPLTNITAALH-----SPLT 2371
Query: 399 LHCEAQRGSLPILYQFHHEGAALERRSANS-AGGVAISFSLTAEH-SGNYYCTADNGFGP 456
L CEA P + F E AGG + + T E SG Y C A N G
Sbjct: 2372 LLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 2431
Query: 457 QRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWS 516
R + S+ V VP S L + +G T L C V G PQ ++ + PL
Sbjct: 2432 AR-RNFSVEVLVPPSIENEDLEEVIKV-LDGQTAHLMCNVT-GHPQPKLTWFKDGRPLAR 2488
Query: 517 SSTPSVGRVSFSFSLTEGH---SGNYYCTADNGFGPQRSEV-VSLFVTVPVSRPILTLRV 572
+ + + + +G+Y C A N G + +S+ + +
Sbjct: 2489 GDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 2548
Query: 573 PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTA------ 626
V + + L CEA P + W AP EAS N+ L
Sbjct: 2549 EEVTVTVNNPISLICEALAFPSPNITWM--------KDGAPF--EASRNIQLLPGTHGLQ 2598
Query: 627 ------EHSGNYSCEANNGLVAQHSDTISLSVIVPVS----RPILTFRAPRAQAVVGDLL 676
E +G Y+C N L + + V++P S P+ + V L
Sbjct: 2599 ILNAQKEDAGQYTCVVTNEL-GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTL 2657
Query: 677 ELHCEALRGSSPILYWFYH-EDVTLGKISAPSGGGASFNLSLT-TEHSGIYSCEADNGLE 734
L CE+ P + W+ + VT G G + T SG Y C A N
Sbjct: 2658 TLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAG 2717
Query: 735 AQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRG----------SPLILY 784
+ L P+ + V G +A ++L EA G +P LY
Sbjct: 2718 EDDQDFNVLIQVPPMFQKV------GDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 2771
Query: 785 -----------RFFHEDVTLGNRSSPS---GGASLNLSLT-AEHSGNYSCEADNGLG 826
++ ED L S GG L + L AE++G YSC+A N +G
Sbjct: 2772 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 2828
Score = 70.9 bits (172), Expect = 6e-12
Identities = 159/613 (25%), Positives = 230/613 (37%), Gaps = 71/613 (11%)
Query: 254 DSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQED 313
DSG Y C A+ S S R + VQ+P P + P G + L+C E
Sbjct: 1093 DSGHYECTASNPAGSA---SHRYVLGVQVP---PQVQPGPRVLKVLVGEALDLNC-VAEG 1145
Query: 314 SLRTLYRFYHEGVPLRHKSVRCERGASISFS-LTTENSGNYYCTADNGLGAKPSKAVSLS 372
+ + +GV L+ + + S+ F+ + T ++G Y C A N G + V L
Sbjct: 1146 NPEPQLSWSKDGVVLQGRGPQ----GSVHFAAIRTSDAGRYRCEASNSAGV-DAWEVELR 1200
Query: 373 VTVPVSHPVLNLSSPEDLI--FEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAG 430
V P P L+ G +L C A RG+ P +G + E +
Sbjct: 1201 VLEP---PHWGADETSGLLERVAGENASLPCPA-RGT-PKPQVTWRKGPSSE--PLHGQP 1253
Query: 431 GVAI-------SFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEAL 483
GVA+ S++ SG+Y C A N G S+ L V VP S A
Sbjct: 1254 GVAVLEEGSLFLASVSPADSGDYECQATNEVG-STSRRAKLVVYVPPSIRE-DGRKANVS 1311
Query: 484 TFEGATVTLHCEVQR-GSPQILY--QFYHEDMPL------WSSSTPSVG-------RVSF 527
G ++TL C+ P+I++ +PL W VG S
Sbjct: 1312 GMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSL 1371
Query: 528 SF-SLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDL---L 583
F + EG SG Y C A+N G + + L +T P L AQ V+G +
Sbjct: 1372 HFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPP-----SVLGAGAAQEVLGLAGADV 1426
Query: 584 ELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEH---SGNYSCEANNGL 640
EL C P + W L E L +T H G Y C A +
Sbjct: 1427 ELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSP- 1485
Query: 641 VAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGD-LLELHCEALRGSSPILYWFYHEDV- 698
Q + L V P + I AV+ D L++L CEA +P + WF +
Sbjct: 1486 AGQQARDFQLRVHAPPT--IWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL 1543
Query: 699 -TLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLR 757
T K+ GG + +G+Y+C+A N + A + L V VP + R
Sbjct: 1544 PTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA-AEKATRLDVYVPPTIEGAGGR 1602
Query: 758 APGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS---PSGGASLNLSLTAE-H 813
A G + L C A RG P + HE + + + + G+ L L E
Sbjct: 1603 PYVVKAVAGRPVALECVA-RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEAS 1661
Query: 814 SGNYSCEADNGLG 826
SG YSC A + G
Sbjct: 1662 SGLYSCVASSPAG 1674
Score = 69.7 bits (169), Expect = 1e-11
Identities = 113/488 (23%), Positives = 193/488 (39%), Gaps = 39/488 (7%)
Query: 162 GAYRCTGYKESCCPVSSNTVKIQVQ-EPFTRPVLRASSFQPISGNPVTLTCETQLSLERS 220
G Y C+ + V+ V + VQ P +P+ S + ++ V L CE + R
Sbjct: 3923 GRYTCSA--RNSAGVAHKHVFLTVQASPVVKPL--PSVVRAVAEEEVLLPCEAS-GIPRP 3977
Query: 221 DVPLRFRFFRDDQTLGLGWSLSPNFQITAMWS--KDSGFYWCKAATMPYSVISDSPRSWI 278
+ + + G+ + P Q+ + +D+G Y C A S + ++ +
Sbjct: 3978 TITWQKEGL--NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMG---KTRL 4032
Query: 279 QVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL---RHKSVRC 335
VQ+P PV+ EG+ L C+ + S + +G P+ K
Sbjct: 4033 VVQVP---PVIENGLPDLSTTEGSHAFLPCKAR-GSPEPNITWDKDGQPVSGAEGKFTIQ 4088
Query: 336 ERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGA 395
G + +L +++G Y CTA+N +G + + V L++ V PV + + G
Sbjct: 4089 PSGELLVKNLEGQDAGTYTCTAENAVG-RARRRVHLTILVL---PVFTTLPGDRSLRLGD 4144
Query: 396 KVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFG 455
++ L C A+ P + ++ E S G +++ E SG Y C A+N G
Sbjct: 4145 RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 4204
Query: 456 PQRSKAVSLSVTVPVSHPVLTLSSAEALTFE--GATVTLHCEVQRGSPQILYQFYHEDMP 513
R++AVS V V + A + E G ++ L C V RG P + + +P
Sbjct: 4205 --RTQAVSF---VHVKEAPVLQGEAFSYLVEPVGGSIQLDCVV-RGDPVPDIHWIKDGLP 4258
Query: 514 LWSSSTP-SVGRVSFSFSLTE-GHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLR 571
L S + S + TE +G Y C A+N G + V + V S P+ +
Sbjct: 4259 LRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVV----ILVLQSAPVFQVE 4314
Query: 572 VPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNL-SLTAEHSG 630
GD + L C+A P + W S + + S L ++ +G
Sbjct: 4315 PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAG 4374
Query: 631 NYSCEANN 638
Y C A+N
Sbjct: 4375 TYDCVAHN 4382
Score = 67.8 bits (164), Expect = 5e-11
Identities = 142/559 (25%), Positives = 211/559 (37%), Gaps = 71/559 (12%)
Query: 349 NSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSL 408
+SG+Y CTA N G+ + V L V VP P + + G + L+C A+
Sbjct: 1093 DSGHYECTASNPAGSASHRYV-LGVQVP---PQVQPGPRVLKVLVGEALDLNCVAEGNPE 1148
Query: 409 PILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTV 468
P L + +G L+ R + A ++ +G Y C A N G + V L V
Sbjct: 1149 PQL-SWSKDGVVLQGRGPQGSVHFA---AIRTSDAGRYRCEASNSAGVD-AWEVELRVLE 1203
Query: 469 PVSHPVLTLSSAEALTFEGATVTLHCEVQRGS--PQILYQFYHEDMPLWSSSTPSVGRVS 526
P H +S G +L C RG+ PQ+ ++ PL P V +
Sbjct: 1204 P-PHWGADETSGLLERVAGENASLPCPA-RGTPKPQVTWRKGPSSEPL--HGQPGVAVLE 1259
Query: 527 ----FSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDL 582
F S++ SG+Y C A N G S L V VP S R + G
Sbjct: 1260 EGSLFLASVSPADSGDYECQATNEVG-STSRRAKLVVYVPPSIR-EDGRKANVSGMAGQS 1317
Query: 583 LELHCEAPRGSPPILYWF--------------YHEDV---TLGSSSAPSGGEASFNLSLT 625
L L C+A P + W Y D+ +G G++ +
Sbjct: 1318 LTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQ 1377
Query: 626 AEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDL---LELHCEA 682
SG YSC A N D L V+ P S A AQ V+G +EL C
Sbjct: 1378 EGDSGLYSCRAENQAGTAQRD-FHLLVLTPPS----VLGAGAAQEVLGLAGADVELQCWT 1432
Query: 683 LRGSSPILYWFYHEDVTLGKISAPSGGGASFN-----LSLTTEH---SGIYSCEADNGLE 734
+P + W L P G L +T H G Y C A +
Sbjct: 1433 SGVPTPQVEWTKDRQPVL-----PGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSP-A 1486
Query: 735 AQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGD-LLELHCEALRGSPLILYRFFHEDVTL 793
Q++ L+V P + + G A + D L++L CEA RG P +F + L
Sbjct: 1487 GQQARDFQLRVHAPPT--IWGSNETGEVAVMEDHLVQLLCEA-RGVPTPNITWFKDGALL 1543
Query: 794 GNRSS---PSGGASLNLS-LTAEHSGNYSCEADNGLG-AQRSETVTLYITGLTANRSG-P 847
+ GG L L + +G Y+C+A N +G A+++ + +Y+ G P
Sbjct: 1544 PTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRP 1603
Query: 848 FAT-GVAGGLLSIAGLAAG 865
+ VAG +++ +A G
Sbjct: 1604 YVVKAVAGRPVALECVARG 1622
Score = 47.0 bits (110), Expect = 9e-05
Identities = 60/235 (25%), Positives = 89/235 (37%), Gaps = 25/235 (10%)
Query: 614 SGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVG 673
SG + L + G Y C A V++ + + IV P AP G
Sbjct: 476 SGNSSWEILRASKAEEGTYECTA----VSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPG 531
Query: 674 DLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGI-------YS 726
+ L C L + L W V ++ S G + L+ E SGI Y
Sbjct: 532 ETAVLSCRVLGEAPYNLTW-----VRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 586
Query: 727 CEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRF 786
C A N R+ + L P +++ H + G +++ C A G P +
Sbjct: 587 CVASNANGVTRASVWLLVREAPQ----VSIHTSSQHFSQGVEVKVSCSA-SGYPTPHISW 641
Query: 787 FHEDVTLGNRSS---PSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYIT 838
E L S + G + + E +GNYSC+A N +G + ETVTLY T
Sbjct: 642 SRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQ-ETVTLYYT 695
Score = 40.8 bits (94), Expect = 0.006
Identities = 72/314 (22%), Positives = 119/314 (37%), Gaps = 40/314 (12%)
Query: 75 LEVQESGEYRCQAQGSP--LSSPVHLDFSSASLILQAP--LSVFEGDSVVLRCRAKAEVT 130
LE Q++G Y C A+ + VHL + P S+ GD + LRC A+ T
Sbjct: 4098 LEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPT 4157
Query: 131 LNNTIYKNDNVLAFLNKRTD----FHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQ 186
ND + D +D+G Y C + E+ + + V+
Sbjct: 4158 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC--WAENRVGRTQAVSFVHVK 4215
Query: 187 EPFTRPVLRASSF----QPISGNPVTLTCETQ------LSLERSDVPLRFRFFRDDQTLG 236
E PVL+ +F +P+ G+ + L C + + + +PLR R G
Sbjct: 4216 EA---PVLQGEAFSYLVEPVGGS-IQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG 4271
Query: 237 LGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKA 296
+ I D+G Y C A + + + S PV + P+
Sbjct: 4272 -------SLTIHRTERDDAGRYQCLAEN------EMGVAKKVVILVLQSAPVFQVEPQDM 4318
Query: 297 LNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLR-HKSVRCERGASISF-SLTTENSGNYY 354
G V L C+ + T+ + G PLR + +R S+ ++ T ++G Y
Sbjct: 4319 TVRSGDDVALRCQATGEPTPTI-EWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 4377
Query: 355 CTADNGLGAKPSKA 368
C A N LG+ ++A
Sbjct: 4378 CVAHNLLGSATARA 4391
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 107 bits (266), Expect = 7e-23
Identities = 197/818 (24%), Positives = 319/818 (38%), Gaps = 121/818 (14%)
Query: 74 ILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSV-----------FEGDSVVLR 122
+L V+++G Y C A+ SP S + +QAP ++ +VL
Sbjct: 2266 VLRVRDAGLYTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLE 2320
Query: 123 CRAKAEVTLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPV 176
C +AE T +++ VL F + + D+G Y CT +
Sbjct: 2321 CSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA---- 2376
Query: 177 SSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSL---ERSDVPLRFRFFRDDQ 233
S +V +V E T P +R SG P Q +L + VP +R D+
Sbjct: 2377 GSTSVAFRV-EIHTVPTIR-------SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDR 2428
Query: 234 T----LGLGWSLSP--NFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHP 287
+ + P + +I + ++D+G Y C A+ S SD ++V P P
Sbjct: 2429 VPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN---SAGSDRQGRDLRVLEP---P 2482
Query: 288 VLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGA-----SIS 342
+ SP T L CE S + L ++ +G L R ++GA S +
Sbjct: 2483 AIAPSPSNLTLTAHTPALLPCEAS-GSPKPLVVWWKDGQKL---DFRLQQGAYRLLPSNA 2538
Query: 343 FSLTT---ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTL 399
LT ++S + C N +G + + ++V VP P + + + A V L
Sbjct: 2539 LLLTAPGPQDSAQFECVVSNEVG-EAHRLYQVTVHVP---PTIADDQTDFTVTMMAPVVL 2594
Query: 400 HCEAQRGSLPILYQFHHEGAALERRSA----NSAGGVAISFSLTAEHSGNYYCTADNGFG 455
C + P + + GA L R + + +G + I +L H+G Y C+A N G
Sbjct: 2595 TCHSTGIPAPTV-SWSKAGAQLGARGSGYRVSPSGALEIGQALPI-HAGRYTCSARNSAG 2652
Query: 456 PQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLW 515
PV P+ ++ A A V L CE G P+ + E + +
Sbjct: 2653 VAHKHVFLTVQASPVVKPLPSVVRAVA----EEEVLLPCEAS-GIPRPTITWQKEGLNVA 2707
Query: 516 SSSTPSV---GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRV 572
+ + V G++ + + E +GNY C A N G + L V VP P++ +
Sbjct: 2708 TGVSTQVLPGGQLRIAHASPED-AGNYLCIAKNSAGSAMGKT-RLVVQVP---PVIENGL 2762
Query: 573 PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAP-SGGEASFNL--------- 622
P G L C+A RGSP ++T P SG E F +
Sbjct: 2763 PDLSTTEGSHAFLPCKA-RGSP-------EPNITWDKDGQPVSGAEGKFTIQPSGELLVK 2814
Query: 623 SLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA 682
+L + +G Y+C A N V + + L+++V P+ T +GD L L C A
Sbjct: 2815 NLEGQDAGTYTCTAENA-VGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWLRCAA 2870
Query: 683 LRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGL-EAQRSEMV 741
+P + W ++ +S GG +++ E SG Y C A+N + Q V
Sbjct: 2871 RGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFV 2930
Query: 742 TLKVAVPVSRPVLTLRA-PGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPS 800
+K A PVL A VG ++L C +RG P+ + + + L R S
Sbjct: 2931 HVKEA-----PVLQGEAFSYLVEPVGGSIQLDC-VVRGDPVPDIHWIKDGLPL--RGSHL 2982
Query: 801 GGASLNLSLT-----AEHSGNYSCEADNGLGAQRSETV 833
N SLT + +G Y C A+N +G + +
Sbjct: 2983 RHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVVI 3020
Score = 106 bits (264), Expect = 1e-22
Identities = 207/857 (24%), Positives = 326/857 (38%), Gaps = 83/857 (9%)
Query: 19 RTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRY----LGKEILRETPDNI 74
+ P I L T V+L C +P+ T WY LG+E+ +
Sbjct: 1652 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVT-WYKDSQALSLGEEVFLLPGTHT 1710
Query: 75 LEV-----QESGEYRCQAQGSP--------LSSPVHLDFSSASLILQAPLSVFEGDSVVL 121
L++ +SG Y C+A + LS V F A Q + V GD VL
Sbjct: 1711 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVL 1770
Query: 122 RCRAKAEVTLNNTIYKNDNVLAFLNKRTD-------FHIPHACLKDNGAYRCTGYKESCC 174
C A T YK+ L L +RT I A + D G Y C +
Sbjct: 1771 SCETDALPEPTVTWYKDGQPLV-LAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE 1829
Query: 175 PVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQT 234
V + T+ +QV F P + + ++G+P+ LTC+ + L+ R +
Sbjct: 1830 AVRTFTLTVQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSA 1887
Query: 235 LGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPE 294
+ S Q++ + +G Y C A + +++ + ++ + A +
Sbjct: 1888 VHGVVSRGGRLQLSRLQPAQAGTYTCVAE----NTQAEARKDFVVAVLVAPRIRSSGVAR 1943
Query: 295 KALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL-----RHKSVRCERGASISFSLTTEN 349
+ EG +V L CE + + +G PL H + G+ + L +
Sbjct: 1944 EHHVLEGQEVRLDCEADGQPPPDV-AWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASD 2002
Query: 350 SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLP 409
+G Y C A N G + ++ +++V VP + S + G VT+ C RGS P
Sbjct: 2003 AGAYTCVAHNPAG-EDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPV-RGSPP 2060
Query: 410 ILYQFHHEGAAL---ERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSV 466
I + +G L +R + +G + +G + C A + G + +L V
Sbjct: 2061 IHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAG-VADRNFTLQV 2119
Query: 467 TV-PVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRV 525
V PV PV + + + G+ V L CE RG P L + + PL S S +
Sbjct: 2120 QVPPVLEPVEFQN--DVVVVRGSLVELPCEA-RGVPLPLVSWMKDGEPLLSQSLEQGPSL 2176
Query: 526 SFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVV-GDLLE 584
++ G SG Y C A + G R +TV I P ++ G +E
Sbjct: 2177 QLE-AVGAGDSGTYSCVAVSEAGEARRH---FQLTVMEPPHIEDSGQPTELSLTPGAPME 2232
Query: 585 LHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQH 644
L C+A P + W H+D G + + L +G Y+C L
Sbjct: 2233 LLCDAQGTPQPNITW--HKD---GQALTRLENNSRATRVLRVRDAGLYTC-----LAESP 2282
Query: 645 SDTISLSVIVPVSRP--ILTFRAPR-AQAVVGDLLELHCEALRGSSPILYWFYHEDVTLG 701
+ I S V V P I+ R PR + L L C +P + W H D +
Sbjct: 2283 AGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITW--HRDGIVL 2340
Query: 702 KISA----PSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLR 757
+ A P G +L+T SG YSC A N A S V +V + + P +
Sbjct: 2341 QEDAHTQFPERGRFLQLQALSTADSGDYSCTARN---AAGSTSVAFRVEIH-TVPTIRSG 2396
Query: 758 APGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS-----PSGGASLNLSLTAE 812
P + +V L C+A G P L + + V L RS P G + + A+
Sbjct: 2397 PPAVNVSVNQTALLPCQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ-PVLAQ 2454
Query: 813 HSGNYSCEADNGLGAQR 829
+G+Y C A N G+ R
Sbjct: 2455 DAGHYLCLASNSAGSDR 2471
Score = 92.8 bits (229), Expect = 1e-18
Identities = 213/899 (23%), Positives = 324/899 (36%), Gaps = 141/899 (15%)
Query: 34 VFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRE-----TPDNIL------EVQESGE 82
V G+ L C P+ T W+ G+ + R +PD +L + +G
Sbjct: 1175 VLDGQTAHLMCNVTGHPQPKLT-WFKD--GRPLARGDAHHISPDGVLLQVLQANLSSAGH 1231
Query: 83 YRCQAQGSPLSSPVHLDFSSASLILQAP-------------LSVFEGDSVVLRCRAKAEV 129
Y C A + H S +L AP ++V + + L C A A
Sbjct: 1232 YSCIAANAVGEKTKHFQLS----VLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFP 1287
Query: 130 TLNNTIYKN------DNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKI 183
+ N T K+ + L I +A +D G Y C E V + V++
Sbjct: 1288 SPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEV 1347
Query: 184 QVQEPFTRP----VLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQ------ 233
+ ++ + + + +TL CE+ + P R+++D Q
Sbjct: 1348 LIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESW-----AVPPPTIRWYKDGQPVTPSS 1402
Query: 234 ---TLGLGWSLSPNFQITAMWSKDSGFYWCKAATMP------YSVISDSPRSWIQV-QIP 283
LG G L QI DSG Y C A + ++V+ P + +V
Sbjct: 1403 RLQVLGEGRLL----QIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFS 1458
Query: 284 ASHPVLTLSPEKALNF-------EGTKVTLHCETQEDSLRTLYRFYHEGVPLR---HKSV 333
A+ +L+ E E L+C+T L +Y E PL SV
Sbjct: 1459 AAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSV 1517
Query: 334 RCERGASISFSLT-TENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIF 392
+ G + L EN+G Y C A N +G L +T PV L E+L+
Sbjct: 1518 -LQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVI-----LGDTEELVE 1571
Query: 393 E-----GAKVTLHCEAQRGSLPILYQFHH--EGAALERRSANSAGGVAISFSLTAEHSGN 445
E + V+L C A +P + + + R G V + + +
Sbjct: 1572 EVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAAS 1631
Query: 446 YYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQ-RGSPQIL 504
Y C A+N G K +L V VP L L A+ ++V+L C+V +P++
Sbjct: 1632 YMCVAENQAG-SAEKLFTLRVQVPPRIAGLDLEQVTAIL--NSSVSLPCDVHAHPNPEVT 1688
Query: 505 Y-------QFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSL 557
+ E L + T +GR S SG Y C A N G + ++V L
Sbjct: 1689 WYKDSQALSLGEEVFLLPGTHTLQLGRARLS------DSGMYTCEALNAAG-RDQKLVQL 1741
Query: 558 FVTVPVSRPILTLRVPRA--QAV---VGDLLELHCEAPRGSPPILYWFYHED--VTLGSS 610
V VP + + PR AV VGD L CE P + W+ V +
Sbjct: 1742 SVLVPPA----FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRT 1797
Query: 611 SAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQA 670
A GG+ G YSC+ +N + + T +L+V VP TF P+ +
Sbjct: 1798 QALRGGQRLEIQEAQVSDKGLYSCKVSN-VAGEAVRTFTLTVQVPP-----TFENPKTET 1851
Query: 671 ---VVGDLLELHCEALRGSSPILYWFYHE-DVTLGKISAPSGGGASFNLS-LTTEHSGIY 725
V G L L C+ +P + W V + G LS L +G Y
Sbjct: 1852 VSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTY 1911
Query: 726 SCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYR 785
+C A+N R + V + P R R H G + L CEA G P
Sbjct: 1912 TCVAENTQAEARKDFVVAVLVAPRIRSSGVARE--HHVLEGQEVRLDCEA-DGQPPPDVA 1968
Query: 786 FFHEDVTLGNRSSP------SGGASLNLSLTAEHSGNYSCEADNGLGAQ-RSETVTLYI 837
+ + LG P GG+ + L A +G Y+C A N G R TV + +
Sbjct: 1969 WLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLV 2027
Score = 91.3 bits (225), Expect = 4e-18
Identities = 203/898 (22%), Positives = 328/898 (36%), Gaps = 136/898 (15%)
Query: 40 VTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNIL------------EVQESGEYRCQA 87
+TL C+ P +W+ G+E + D L + Q+SG Y C A
Sbjct: 1088 LTLLCEAMGI-PPPAIRWFR---GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1143
Query: 88 QGSPLSSPVHLDFSSASLI--------LQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKND 139
+ +FS L+ L+ + V +G + L C T +K+
Sbjct: 1144 SNE--AGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDG 1201
Query: 140 NVLAFLNKRTDFH----------IPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPF 189
LA R D H + A L G Y C V T Q+
Sbjct: 1202 RPLA----RGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA----VGEKTKHFQLSVLL 1253
Query: 190 TRPVLRA---SSFQPIS---GNPVTLTCET------QLSLERSDVPLRFRFFRDDQTLGL 237
+L S+ + ++ NP++L CE ++ + P F R+ Q L
Sbjct: 1254 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAP--FEASRNIQLLPG 1311
Query: 238 GWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSW-IQVQIPAS----HPVLTLS 292
L QI +D+G Y C + + ++ +++ ++V IP S P+ +
Sbjct: 1312 THGL----QILNAQKEDAGQYTCVVT----NELGEAVKNYHVEVLIPPSISKDDPLAEVG 1363
Query: 293 PEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLT---TEN 349
++ + +TL CE+ T+ R+Y +G P+ S G + +
Sbjct: 1364 VKEVKTKVNSTLTLECESWAVPPPTI-RWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSD 1422
Query: 350 SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDL----------------IFE 393
SG Y C A N G L P+ V + S+ ++ I E
Sbjct: 1423 SGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVE 1482
Query: 394 GAKVTLHCEAQRGSLPILYQFHHEG--AALERRSANSAGGVAISFSLTAEHSGNYYCTAD 451
L+C+ P L + + +A + S G V + AE++G Y C A
Sbjct: 1483 NNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS 1542
Query: 452 NGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFE-----GATVTLHCEVQRGSPQILYQ 506
N G L +T PV L E L E +TV+L C G+P
Sbjct: 1543 NEVGEDWLHYELLVLTPPV-----ILGDTEELVEEVTVNASSTVSLQCPAL-GNPVPTIS 1596
Query: 507 FYHEDMPLWSSSTPSV---GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPV 563
+ +P S V G+V + + +Y C A+N G ++ +L V VP
Sbjct: 1597 WLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG-SAEKLFTLRVQVPP 1655
Query: 564 SRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHED-VTLGSSSAPSGGEASFNL 622
I L + + A++ + L C+ P + W+ ++LG G + L
Sbjct: 1656 R--IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQL 1713
Query: 623 SLTA-EHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFR-APRA--QAV---VGDL 675
SG Y+CEA N + + LSV+VP + FR APR AV VGD
Sbjct: 1714 GRARLSDSGMYTCEALNA-AGRDQKLVQLSVLVPPA-----FRQAPRGPQDAVLVRVGDK 1767
Query: 676 LELHCEALRGSSPILYWFYH-EDVTLGKISAPSGGGASFNLS-LTTEHSGIYSCEADNGL 733
L CE P + W+ + + L + + GG + G+YSC+ N
Sbjct: 1768 AVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVA 1827
Query: 734 -EAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVT 792
EA R+ +T++V P + G L L C+ + G P + + +
Sbjct: 1828 GEAVRTFTLTVQVPPTFENP----KTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRMP 1882
Query: 793 LGNRSSP---SGGASLNLS-LTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSG 846
+ + + S G L LS L +G Y+C A+N R + V + SG
Sbjct: 1883 VESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG 1940
Score = 79.3 bits (194), Expect = 2e-14
Identities = 102/392 (26%), Positives = 160/392 (40%), Gaps = 27/392 (6%)
Query: 348 ENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGS 407
E++GNY C A N G+ K L V VP PV+ P+ EG+ L C+A RGS
Sbjct: 2728 EDAGNYLCIAKNSAGSAMGKT-RLVVQVP---PVIENGLPDLSTTEGSHAFLPCKA-RGS 2782
Query: 408 LPILYQFHHEG---AALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSL 464
+ +G + E + G + +L + +G Y CTA+N G R + V L
Sbjct: 2783 PEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR-VHL 2841
Query: 465 SVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGR 524
++ V PV T + G + L C RGSP + D P+ + G
Sbjct: 2842 TILVL---PVFTTLPGDRSLRLGDRLWLRCAA-RGSPTPRIGWTVNDRPVTEGVSEQDGG 2897
Query: 525 VSFS-FSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLL 583
+ +++ SG Y C A+N G R++ VS FV V + + VG +
Sbjct: 2898 STLQRAAVSREDSGTYVCWAENRVG--RTQAVS-FVHVKEAPVLQGEAFSYLVEPVGGSI 2954
Query: 584 ELHCEAPRGSP-PILYWFYHEDVTLGSSSAPSGGEASFNLSLTA-EHSGNYSCEANNGL- 640
+L C RG P P ++W GS S + T + +G Y C A N +
Sbjct: 2955 QLDCVV-RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMG 3013
Query: 641 VAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFY-HEDVT 699
VA+ + ++V S P+ GD + L C+A +P + W + +
Sbjct: 3014 VAK-----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR 3068
Query: 700 LGKISAPSGGGASFNLSLTTEHSGIYSCEADN 731
+ G+ + ++ T +G Y C A N
Sbjct: 3069 ASRRLRTLPDGSLWLENVETGDAGTYDCVAHN 3100
Score = 76.6 bits (187), Expect = 1e-13
Identities = 134/520 (25%), Positives = 188/520 (36%), Gaps = 84/520 (16%)
Query: 349 NSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSL 408
+ G Y C A N L + + V+L V VP P + + E A VTL C A
Sbjct: 577 DEGIYTCAATN-LAGESKREVALKVLVP---PNIEPGPVNKAVLENASVTLECLASGVPP 632
Query: 409 PILYQF--HHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSV 466
P + F H ++ + + G V +G+Y C A N G + L V
Sbjct: 633 PDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELR-YGLRV 691
Query: 467 TVPVSHPVLTLS-SAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSV--- 522
VP P +TL S V L C G+P + + P+ + TP +
Sbjct: 692 NVP---PRITLPPSLPGPVLVNTPVRLTCNAT-GAPSPTLMWLKDGNPVSPAGTPGLQVF 747
Query: 523 --GRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVG 580
GRV S SG Y C A + G R +VV L V +P P + V
Sbjct: 748 PGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV-LQVHMP---PSILGEELNVSVVAN 803
Query: 581 DLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTAEHS----------- 629
+ + L C++ PP+L W+ G P G + L+A+ +
Sbjct: 804 ESVALECQSHAMPPPVLSWWKD-----GRPLEPRPG-----VHLSADKALLQVDRADVWD 853
Query: 630 -GNYSCEANNGLVAQHSDT-ISLSVIVPVSRPILTFRAPRAQAV-VGDLLELHCEALRGS 686
G+Y+CEA N A HS+ +L+V V P+ R V G L CE
Sbjct: 854 AGHYTCEALNQ--AGHSEKHYNLNVWVA---PVFPLRESHTLTVREGHPTRLSCECRGVP 908
Query: 687 SPILYW------FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEM 740
P + W E L +SA G + G Y+CE N + S+
Sbjct: 909 FPKISWRKDGQPLPGEGAGLQHVSAV--GRLLYLGQAQLAQEGTYTCECSN-VVGNSSQD 965
Query: 741 VTLKVAVPVSRPVLTLRAPGTHAAV--GDLLELHCEALRGSPLILYRFFHEDVTLGNRSS 798
+ L+V VP + R P T +V + L C A P R
Sbjct: 966 LQLEVHVPPQ--IAGPREPPTQVSVVQDGVATLECNATGKPP---------PTVTWERDG 1014
Query: 799 PSGGASLNLSLT------------AEHSGNYSCEADNGLG 826
GA L L L A H+G YSC A+N G
Sbjct: 1015 QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAG 1054
Score = 76.3 bits (186), Expect = 1e-13
Identities = 185/837 (22%), Positives = 290/837 (34%), Gaps = 141/837 (16%)
Query: 79 ESGEYRCQAQGSPLSSPVHLDFSSASLILQAP---------LSVFEGDSVVLRCRAKAEV 129
+SG Y C A S V D L + P +SV +SV L C++ A
Sbjct: 762 DSGRYSCVAV-----SAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMP 816
Query: 130 TLNNTIYKNDNVLA------FLNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKI 183
+ +K+ L + + A + D G Y C ++ + +
Sbjct: 817 PPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 876
Query: 184 QVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPL-RFRFFRDDQTL-GLGWSL 241
V F P+ + + G+P L+CE + VP + + +D Q L G G L
Sbjct: 877 WVAPVF--PLRESHTLTVREGHPTRLSCECR------GVPFPKISWRKDGQPLPGEGAGL 928
Query: 242 SPNFQITAMWS------KDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEK 295
+ + G Y C+ + + V + S ++V +P P +
Sbjct: 929 QHVSAVGRLLYLGQAQLAQEGTYTCECSNV---VGNSSQDLQLEVHVPPQIAGPREPPTQ 985
Query: 296 ALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTE------- 348
+ TL C T+ + +G P+ GA + L +
Sbjct: 986 VSVVQDGVATLECNATGKPPPTV-TWERDGQPV---------GAELGLQLQNQGQSLHVE 1035
Query: 349 -----NSGNYYCTADNGLGAKPSKAVSLSVTVPVS-----HPVLNLSSPEDLIFEGAKVT 398
++G Y C A+N L + + LSV VP P+ N+++ + +T
Sbjct: 1036 RAQAAHTGRYSCVAEN-LAGRAERKFELSVLVPPELIGDLDPLTNITAALH-----SPLT 1089
Query: 399 LHCEAQRGSLPILYQFHHEGAALERRSANS-AGGVAISFSLTAEH-SGNYYCTADNGFGP 456
L CEA P + F E AGG + + T E SG Y C A N G
Sbjct: 1090 LLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 1149
Query: 457 QRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWS 516
R + S+ V VP S L + +G T L C V G PQ ++ + PL
Sbjct: 1150 AR-RNFSVEVLVPPSIENEDLEEVIKV-LDGQTAHLMCNVT-GHPQPKLTWFKDGRPLAR 1206
Query: 517 SSTPSVGRVSFSFSLTEGH---SGNYYCTADNGFGPQRSEV-VSLFVTVPVSRPILTLRV 572
+ + + + +G+Y C A N G + +S+ + +
Sbjct: 1207 GDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1266
Query: 573 PRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLTA------ 626
V + + L CEA P + W AP EAS N+ L
Sbjct: 1267 EEVTVTVNNPISLICEALAFPSPNITWM--------KDGAPF--EASRNIQLLPGTHGLQ 1316
Query: 627 ------EHSGNYSCEANNGLVAQHSDTISLSVIVPVS----RPILTFRAPRAQAVVGDLL 676
E +G Y+C N L + + V++P S P+ + V L
Sbjct: 1317 ILNAQKEDAGQYTCVVTNEL-GEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTL 1375
Query: 677 ELHCEALRGSSPILYWFYH-EDVTLGKISAPSGGGASFNLSLT-TEHSGIYSCEADNGLE 734
L CE+ P + W+ + VT G G + T SG Y C A N
Sbjct: 1376 TLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAG 1435
Query: 735 AQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRG----------SPLILY 784
+ L P+ + V G +A ++L EA G +P LY
Sbjct: 1436 EDDQDFNVLIQVPPMFQKV------GDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1489
Query: 785 -----------RFFHEDVTLGNRSSPS---GGASLNLSLT-AEHSGNYSCEADNGLG 826
++ ED L S GG L + L AE++G YSC+A N +G
Sbjct: 1490 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1546
Score = 75.5 bits (184), Expect = 2e-13
Identities = 188/748 (25%), Positives = 273/748 (36%), Gaps = 107/748 (14%)
Query: 145 LNKRTDFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPI-- 202
L++ H P D+G Y C E+ + + V P + VL A + Q +
Sbjct: 83 LDEGQSLHFPRIQEGDSGLYSCRA--ENQAGTAQRDFHLLVLTPPS--VLGAGAAQEVLG 138
Query: 203 -SGNPVTLTCETQLSLERSDVPL-RFRFFRDDQTLGLGWSLSPNFQ---------ITAMW 251
+G V L C T S VP + + +D Q + G P+ Q IT
Sbjct: 139 LAGADVELQCWT------SGVPTPQVEWTKDRQPVLPG---GPHLQVQEDGQVLRITGSH 189
Query: 252 SKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPE--KALNFEGTKVTLHCE 309
D G Y C A +S R + Q+++ A P + S E + E V L CE
Sbjct: 190 VGDEGRYQCVA----FSPAGQQARDF-QLRVHAP-PTIWGSNETGEVAVMEDHLVQLLCE 243
Query: 310 TQEDSLRTLYRFYHEG--VPLRHKSVRCERGASISFSLT-TENSGNYYCTADNGLGAKPS 366
+ + ++ +G +P K V G + + ++G Y C A N +GA
Sbjct: 244 ARGVPTPNI-TWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAA-E 301
Query: 367 KAVSLSVTVPVSHPVLNLSSPEDLIFE---GAKVTLHCEAQRGSLPILYQFHHEG--AAL 421
KA L V VP P + + + + G V L C A+ P L +HHEG A
Sbjct: 302 KATRLDVYVP---PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL-SWHHEGLPVAE 357
Query: 422 ERRSANSAGGVAISFSLTAE-HSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSS- 479
S G + E SG Y C A + P + SV V V +L
Sbjct: 358 SNESRLETDGSVLRLESPGEASSGLYSCVASS---PAGEAVLQYSVEVQVPPQLLVAEGL 414
Query: 480 AEALTFEGATVTLHCEVQRGSPQILYQFYHEDMP---LWSSSTPSVGRVSFSFSLTEGHS 536
+ T G + L C+ GSP Q+ P L S G + HS
Sbjct: 415 GQVTTIVGQPLELPCQAS-GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHS 473
Query: 537 GNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPI 596
G + C A N G +EV V+V L VP Q G E H P P
Sbjct: 474 GLFACQATNEAGTAGAEVE---VSVHGEWAPGVLEVPIGQYHWGX--EHHSSFPAACDPP 528
Query: 597 LY--WFYHEDVTLGSS--------SAPSGGEASFNL-------SLTAEHSGNYSCEANNG 639
++ W H L P+G +++L + G Y+C A N
Sbjct: 529 VHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATN- 587
Query: 640 LVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDL-LELHCEALRGSSPILYWFY-HED 697
L + ++L V+VP + P +AV+ + + L C A P + WF H+
Sbjct: 588 LAGESKREVALKVLVPPNIE----PGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQP 643
Query: 698 VTLGKISAPSGGGASFNLSLTT-EHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTL 756
V+ S G + +G Y C A N + L+V VP R L
Sbjct: 644 VSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN-VAGSTELRYGLRVNVP-PRITLPP 701
Query: 757 RAPGTHAAVGDLLELHCEALRG-SPLILYRFFHEDVTLGNRSSPSGGASLNL-------- 807
PG V + L C A SP +++ + GN SP+G L +
Sbjct: 702 SLPGP-VLVNTPVRLTCNATGAPSPTLMW------LKDGNPVSPAGTPGLQVFPGGRVLT 754
Query: 808 --SLTAEHSGNYSCEADNGLGAQRSETV 833
S A SG YSC A + +G R + V
Sbjct: 755 LASARASDSGRYSCVAVSAVGEDRQDVV 782
Score = 69.7 bits (169), Expect = 1e-11
Identities = 113/488 (23%), Positives = 193/488 (39%), Gaps = 39/488 (7%)
Query: 162 GAYRCTGYKESCCPVSSNTVKIQVQ-EPFTRPVLRASSFQPISGNPVTLTCETQLSLERS 220
G Y C+ + V+ V + VQ P +P+ S + ++ V L CE + R
Sbjct: 2641 GRYTCSA--RNSAGVAHKHVFLTVQASPVVKPL--PSVVRAVAEEEVLLPCEAS-GIPRP 2695
Query: 221 DVPLRFRFFRDDQTLGLGWSLSPNFQITAMWS--KDSGFYWCKAATMPYSVISDSPRSWI 278
+ + + G+ + P Q+ + +D+G Y C A S + ++ +
Sbjct: 2696 TITWQKEGL--NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMG---KTRL 2750
Query: 279 QVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPL---RHKSVRC 335
VQ+P PV+ EG+ L C+ + S + +G P+ K
Sbjct: 2751 VVQVP---PVIENGLPDLSTTEGSHAFLPCKAR-GSPEPNITWDKDGQPVSGAEGKFTIQ 2806
Query: 336 ERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGA 395
G + +L +++G Y CTA+N +G + + V L++ V PV + + G
Sbjct: 2807 PSGELLVKNLEGQDAGTYTCTAENAVG-RARRRVHLTILVL---PVFTTLPGDRSLRLGD 2862
Query: 396 KVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFG 455
++ L C A+ P + ++ E S G +++ E SG Y C A+N G
Sbjct: 2863 RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 2922
Query: 456 PQRSKAVSLSVTVPVSHPVLTLSSAEALTFE--GATVTLHCEVQRGSPQILYQFYHEDMP 513
R++AVS V V + A + E G ++ L C V RG P + + +P
Sbjct: 2923 --RTQAVSF---VHVKEAPVLQGEAFSYLVEPVGGSIQLDCVV-RGDPVPDIHWIKDGLP 2976
Query: 514 LWSSSTP-SVGRVSFSFSLTE-GHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRPILTLR 571
L S + S + TE +G Y C A+N G + V + V S P+ +
Sbjct: 2977 LRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVV----ILVLQSAPVFQVE 3032
Query: 572 VPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNL-SLTAEHSG 630
GD + L C+A P + W S + + S L ++ +G
Sbjct: 3033 PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAG 3092
Query: 631 NYSCEANN 638
Y C A+N
Sbjct: 3093 TYDCVAHN 3100
Score = 41.2 bits (95), Expect = 0.005
Identities = 72/314 (22%), Positives = 119/314 (37%), Gaps = 40/314 (12%)
Query: 75 LEVQESGEYRCQAQGSP--LSSPVHLDFSSASLILQAP--LSVFEGDSVVLRCRAKAEVT 130
LE Q++G Y C A+ + VHL + P S+ GD + LRC A+ T
Sbjct: 2816 LEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPT 2875
Query: 131 LNNTIYKNDNVLAFLNKRTD----FHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQ 186
ND + D +D+G Y C + E+ + + V+
Sbjct: 2876 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVC--WAENRVGRTQAVSFVHVK 2933
Query: 187 EPFTRPVLRASSF----QPISGNPVTLTCETQ------LSLERSDVPLRFRFFRDDQTLG 236
E PVL+ +F +P+ G+ + L C + + + +PLR R G
Sbjct: 2934 EA---PVLQGEAFSYLVEPVGGS-IQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG 2989
Query: 237 LGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKA 296
+ I D+G Y C A + + + S PV + P+
Sbjct: 2990 -------SLTIRRTERDDAGRYQCLAEN------EMGVAKKVVILVLQSAPVFQVEPQDM 3036
Query: 297 LNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLR-HKSVRCERGASISF-SLTTENSGNYY 354
G V L C+ + T+ + G PLR + +R S+ ++ T ++G Y
Sbjct: 3037 TVRSGDDVALRCQATGEPTPTI-EWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 3095
Query: 355 CTADNGLGAKPSKA 368
C A N LG+ ++A
Sbjct: 3096 CVAHNLLGSATARA 3109
Score = 32.0 bits (71), Expect = 2.9
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 9/74 (12%)
Query: 802 GASLNLSLTAE-HSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIA 860
G SL+ E SG YSC A+N G + + L +T P + AG +
Sbjct: 86 GQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLT--------PPSVLGAGAAQEVL 137
Query: 861 GLAAGALLLYCWLS 874
GLA + L CW S
Sbjct: 138 GLAGADVELQCWTS 151
>gi|189083842 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform d precursor [Homo sapiens]
Length = 253
Score = 106 bits (264), Expect = 1e-22
Identities = 89/271 (32%), Positives = 128/271 (47%), Gaps = 35/271 (12%)
Query: 3 LWVILL----VLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ--KTK 56
+W +LL +L +G P+ ++FL+P W V + + VTL C+G YSP+ T+
Sbjct: 1 MWQLLLPTALLLLVSAGMRTDLPKAVVFLEPQWYRVLEKDSVTLKCQG--AYSPEDNSTQ 58
Query: 57 WYHRYLGKEILRETPDNIL----EVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLS 112
W+H + ++ + V +SGEYRCQ S LS PV L+ L+LQAP
Sbjct: 59 WFH---NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRW 115
Query: 113 VF-EGDSVVLRCRAKAEVTLNNTIY-KNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYK 170
VF E D + LRC + L+ Y +N + + +DF+IP A LKD+G+Y C G
Sbjct: 116 VFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLF 175
Query: 171 ESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFR 230
S VSS TV I + + V SSF P G V+ C + L D
Sbjct: 176 GS-KNVSSETVNITITQGLA--VSTISSFFP-PGYQVSF-CLVMVLLFAVDT-------- 222
Query: 231 DDQTLGLGWSLSPNFQITAMWSKDSGFYWCK 261
GL +S+ N + + KD F W K
Sbjct: 223 -----GLYFSVKTNIRSSTRDWKDHKFKWRK 248
Score = 33.5 bits (75), Expect = 1.00
Identities = 44/203 (21%), Positives = 91/203 (44%), Gaps = 19/203 (9%)
Query: 92 LSSPVHLDFSSASLILQAP-LSVFEGDSVVLRCRAKAEVTLNNTI-YKNDNVLAFLNKRT 149
+S+ + D A + L+ V E DSV L+C+ N+T + N+++++ ++ +
Sbjct: 14 VSAGMRTDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLIS--SQAS 71
Query: 150 DFHIPHACLKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTL 209
+ I A + D+G YRC ++ S+ V+++V + +L+A + +P+ L
Sbjct: 72 SYFIDAATVDDSGEYRC----QTNLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHL 125
Query: 210 TCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSV 269
C + + V + + + + +F I KDSG Y+C+ +V
Sbjct: 126 RCHSWKNTALHKVT-----YLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNV 180
Query: 270 ISDSPRSWIQVQIPASHPVLTLS 292
S++ + + I V T+S
Sbjct: 181 SSET----VNITITQGLAVSTIS 199
>gi|4503675 Fc fragment of IgE, high affinity I, receptor for; alpha
polypeptide precursor [Homo sapiens]
Length = 257
Score = 103 bits (257), Expect = 8e-22
Identities = 64/173 (36%), Positives = 90/173 (52%), Gaps = 10/173 (5%)
Query: 2 LLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRY 61
LL V LL AP G A +P + L PPW +F+GE VTLTC G F+ TKW+H
Sbjct: 10 LLCVALLFFAP-DGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFH-- 66
Query: 62 LGKEILRETPDNI----LEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLS-VFEG 116
+ ET ++ + ++SGEY+CQ Q S PV+L+ S L+LQA V EG
Sbjct: 67 -NGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEG 125
Query: 117 DSVVLRCRAKAEVTLNNTI-YKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTG 168
+ LRC + I YK+ L + + + I +A ++D+G Y CTG
Sbjct: 126 QPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTG 178
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/181 (24%), Positives = 83/181 (45%), Gaps = 22/181 (12%)
Query: 113 VFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKES 172
+F+G++V L C +++T + ++ L+ + +I +A +D+G Y+C + +
Sbjct: 41 IFKGENVTLTCNGNNFFEVSSTKWFHNGSLSE-ETNSSLNIVNAKFEDSGEYKCQHQQVN 99
Query: 173 CCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDD 232
S V ++V + +L+AS+ + G P+ L C DV + +++D
Sbjct: 100 ----ESEPVYLEVFSDWL--LLQASAEVVMEGQPLFLRCH---GWRNWDV-YKVIYYKDG 149
Query: 233 QTLGLGWSLSPNFQITAMWSKDSGFYWC--KAATMPYS------VISDSPRS--WIQVQI 282
+ L W + N IT +DSG Y+C K + Y + +PR W+Q I
Sbjct: 150 EALKY-WYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVIKAPREKYWLQFFI 208
Query: 283 P 283
P
Sbjct: 209 P 209
Score = 37.0 bits (84), Expect = 0.090
Identities = 46/165 (27%), Positives = 69/165 (41%), Gaps = 19/165 (11%)
Query: 380 PVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLT 439
P ++L+ P + IF+G VTL C ++ H G +L + +S V F
Sbjct: 30 PKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNG-SLSEETNSSLNIVNAKF--- 85
Query: 440 AEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRG 499
E SG Y C S+ V L V S +L +SAE + EG + L C R
Sbjct: 86 -EDSGEYKCQHQQ---VNESEPVYLEV---FSDWLLLQASAE-VVMEGQPLFLRCHGWRN 137
Query: 500 SP--QILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCT 542
+++Y E + W + +S + + E SG YYCT
Sbjct: 138 WDVYKVIYYKDGEALKYWYEN----HNISITNATVE-DSGTYYCT 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,044,295
Number of Sequences: 37866
Number of extensions: 1946179
Number of successful extensions: 8722
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 277
Number of HSP's that attempted gapping in prelim test: 5143
Number of HSP's gapped (non-prelim): 2116
length of query: 977
length of database: 18,247,518
effective HSP length: 112
effective length of query: 865
effective length of database: 14,006,526
effective search space: 12115644990
effective search space used: 12115644990
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.