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Search of human proteins with 157688564
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo
sapiens]
(1117 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens] 2294 0.0
gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens] 1820 0.0
gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens] 1803 0.0
gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens] 1803 0.0
gi|4758156 diacylglycerol kinase, iota [Homo sapiens] 1164 0.0
gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens] 293 6e-79
gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens] 291 2e-78
gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens] 285 2e-76
gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 1e-74
gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 1e-74
gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 1e-74
gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 1e-74
gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens] 270 7e-72
gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens] 253 7e-67
gi|40806175 diacylglycerol kinase, theta [Homo sapiens] 238 3e-62
gi|4503313 diacylglycerol kinase epsilon [Homo sapiens] 216 1e-55
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] 152 2e-36
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 152 2e-36
gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo ... 150 6e-36
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ... 150 6e-36
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 134 6e-31
gi|223634006 hypothetical protein LOC441869 [Homo sapiens] 57 7e-08
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 54 1e-06
gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled... 53 1e-06
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled... 53 1e-06
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 51 7e-06
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 51 7e-06
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 50 9e-06
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 50 9e-06
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 50 9e-06
>gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]
Length = 1117
Score = 2294 bits (5945), Expect = 0.0
Identities = 1117/1117 (100%), Positives = 1117/1117 (100%)
Query: 1 METFFRRHFRGKVPGPGEGQQRPSSVGLPTGKARRRSPAGQASSSLAQRRRSSAQLQGCL 60
METFFRRHFRGKVPGPGEGQQRPSSVGLPTGKARRRSPAGQASSSLAQRRRSSAQLQGCL
Sbjct: 1 METFFRRHFRGKVPGPGEGQQRPSSVGLPTGKARRRSPAGQASSSLAQRRRSSAQLQGCL 60
Query: 61 LSCGVRAQGSSRRRSSTVPPSCNPRFIVDKVLTPQPTTVGAQLLGAPLLLTGLVGMNEEE 120
LSCGVRAQGSSRRRSSTVPPSCNPRFIVDKVLTPQPTTVGAQLLGAPLLLTGLVGMNEEE
Sbjct: 61 LSCGVRAQGSSRRRSSTVPPSCNPRFIVDKVLTPQPTTVGAQLLGAPLLLTGLVGMNEEE 120
Query: 121 GVQEDVVAEASSAIQPGTKTPGPPPPRGAQPLLPLPRYLRRASSHLLPADAVYDHALWGL 180
GVQEDVVAEASSAIQPGTKTPGPPPPRGAQPLLPLPRYLRRASSHLLPADAVYDHALWGL
Sbjct: 121 GVQEDVVAEASSAIQPGTKTPGPPPPRGAQPLLPLPRYLRRASSHLLPADAVYDHALWGL 180
Query: 181 HGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALRRKAAGPQAWSA 240
HGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALRRKAAGPQAWSA
Sbjct: 181 HGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALRRKAAGPQAWSA 240
Query: 241 LLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCY 300
LLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCY
Sbjct: 241 LLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCY 300
Query: 301 VGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVR 360
VGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVR
Sbjct: 301 VGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVR 360
Query: 361 HHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCS 420
HHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCS
Sbjct: 361 HHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCS 420
Query: 421 LGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSP 480
LGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSP
Sbjct: 421 LGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSP 480
Query: 481 LMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILAC 540
LMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILAC
Sbjct: 481 LMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILAC 540
Query: 541 GGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEG 600
GGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEG
Sbjct: 541 GGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEG 600
Query: 601 NVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANP 660
NVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANP
Sbjct: 601 NVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANP 660
Query: 661 EKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIP 720
EKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIP
Sbjct: 661 EKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIP 720
Query: 721 RYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTT 780
RYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTT
Sbjct: 721 RYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTT 780
Query: 781 SKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRV 840
SKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRV
Sbjct: 781 SKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRV 840
Query: 841 SMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKL 900
SMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKL
Sbjct: 841 SMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKL 900
Query: 901 SPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLP 960
SPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLP
Sbjct: 901 SPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLP 960
Query: 961 TSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAV 1020
TSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAV
Sbjct: 961 TSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAV 1020
Query: 1021 STGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG 1080
STGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG
Sbjct: 1021 STGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG 1080
Query: 1081 DTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 1117
DTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
Sbjct: 1081 DTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 1117
>gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens]
Length = 945
Score = 1820 bits (4713), Expect = 0.0
Identities = 890/933 (95%), Positives = 895/933 (95%), Gaps = 14/933 (1%)
Query: 185 RRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALRRKAAGPQAWSALLAK 244
RR +R Q P + GT AG + R R L R+QV+ R K
Sbjct: 27 RRRCRRGEEAQVAQPWPEGSRGTAAGPPVEERFRQLHLRKQVSYR--------------K 72
Query: 245 AITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQ 304
AITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQ
Sbjct: 73 AITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQ 132
Query: 305 YCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWV 364
YCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWV
Sbjct: 133 YCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWV 192
Query: 365 HRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVH 424
HRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVH
Sbjct: 193 HRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVH 252
Query: 425 AAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKP 484
AAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKP
Sbjct: 253 AAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKP 312
Query: 485 LLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDG 544
LLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDG
Sbjct: 313 LLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDG 372
Query: 545 TVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQ 604
TVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQ
Sbjct: 373 TVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQ 432
Query: 605 LDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFN 664
LDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFN
Sbjct: 433 LDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFN 492
Query: 665 SRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCA 724
SRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCA
Sbjct: 493 SRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCA 552
Query: 725 GTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAI 784
GTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAI
Sbjct: 553 GTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAI 612
Query: 785 PVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHD 844
PVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHD
Sbjct: 613 PVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHD 672
Query: 845 YEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKW 904
YEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKW
Sbjct: 673 YEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKW 732
Query: 905 CFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPC 964
CFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPC
Sbjct: 733 CFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPC 792
Query: 965 SPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGS 1024
SPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGS
Sbjct: 793 SPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGS 852
Query: 1025 KDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPR 1084
KDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPR
Sbjct: 853 KDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPR 912
Query: 1085 QRAEKAQDTELAAYLENRQHYQMIQREDQETAV 1117
QRAEKAQDTELAAYLENRQHYQMIQREDQETAV
Sbjct: 913 QRAEKAQDTELAAYLENRQHYQMIQREDQETAV 945
>gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]
Length = 929
Score = 1803 bits (4669), Expect = 0.0
Identities = 874/875 (99%), Positives = 874/875 (99%), Gaps = 1/875 (0%)
Query: 244 KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE 303
KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE
Sbjct: 55 KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE 114
Query: 304 QYCVARML-KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH 362
QYCVARML KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH
Sbjct: 115 QYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH 174
Query: 363 WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG 422
WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG
Sbjct: 175 WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG 234
Query: 423 VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM 482
VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM
Sbjct: 235 VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM 294
Query: 483 KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG 542
KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG
Sbjct: 295 KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG 354
Query: 543 DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV 602
DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV
Sbjct: 355 DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV 414
Query: 603 VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK 662
VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK
Sbjct: 415 VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK 474
Query: 663 FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY 722
FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY
Sbjct: 475 FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY 534
Query: 723 CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK 782
CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK
Sbjct: 535 CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK 594
Query: 783 AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM 842
AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM
Sbjct: 595 AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM 654
Query: 843 HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP 902
HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP
Sbjct: 655 HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP 714
Query: 903 KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS 962
KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS
Sbjct: 715 KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS 774
Query: 963 PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST 1022
PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST
Sbjct: 775 PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST 834
Query: 1023 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT 1082
GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT
Sbjct: 835 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT 894
Query: 1083 PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 1117
PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
Sbjct: 895 PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 929
>gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens]
Length = 895
Score = 1803 bits (4669), Expect = 0.0
Identities = 874/875 (99%), Positives = 874/875 (99%), Gaps = 1/875 (0%)
Query: 244 KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE 303
KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE
Sbjct: 21 KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE 80
Query: 304 QYCVARML-KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH 362
QYCVARML KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH
Sbjct: 81 QYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH 140
Query: 363 WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG 422
WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG
Sbjct: 141 WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG 200
Query: 423 VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM 482
VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM
Sbjct: 201 VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM 260
Query: 483 KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG 542
KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG
Sbjct: 261 KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG 320
Query: 543 DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV 602
DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV
Sbjct: 321 DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV 380
Query: 603 VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK 662
VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK
Sbjct: 381 VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK 440
Query: 663 FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY 722
FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY
Sbjct: 441 FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY 500
Query: 723 CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK 782
CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK
Sbjct: 501 CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK 560
Query: 783 AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM 842
AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM
Sbjct: 561 AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM 620
Query: 843 HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP 902
HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP
Sbjct: 621 HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP 680
Query: 903 KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS 962
KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS
Sbjct: 681 KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS 740
Query: 963 PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST 1022
PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST
Sbjct: 741 PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST 800
Query: 1023 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT 1082
GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT
Sbjct: 801 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT 860
Query: 1083 PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 1117
PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
Sbjct: 861 PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 895
>gi|4758156 diacylglycerol kinase, iota [Homo sapiens]
Length = 1065
Score = 1164 bits (3010), Expect = 0.0
Identities = 586/974 (60%), Positives = 720/974 (73%), Gaps = 95/974 (9%)
Query: 213 LPTRVRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQI 272
L ++R L+ R+QV+ R KAI+++GLQHLAP P + ++
Sbjct: 118 LEEKLRNLTFRKQVSYR--------------KAISRAGLQHLAPAHPLSLPVANGPAKEP 163
Query: 273 RSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIE 332
R+T+DWSE+A GEH+W ETNVSGD CY+GE+ C R KS RRKCA CKIVVHT CIE
Sbjct: 164 RATLDWSENAVNGEHLWLETNVSGDLCYLGEENCQVRFAKSALRRKCAVCKIVVHTACIE 223
Query: 333 QLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIV 392
QLEKINFRCKP+FRE GSR+ RE FVRHHWVHRRRQ+GKC+ CGKGFQQKF+FHSKEIV
Sbjct: 224 QLEKINFRCKPTFREGGSRSPRE-NFVRHHWVHRRRQEGKCKQCGKGFQQKFSFHSKEIV 282
Query: 393 AISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKAS-KKKK 451
AISCSWCKQA+H+KV+CFML IEEPCSLG HAAV++PPTWI++ ++PQN+LKAS +KKK
Sbjct: 283 AISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPPTWIIKVKKPQNSLKASNRKKK 342
Query: 452 RASFKRKSSKKGPE-EGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLN 510
R SFKRK+SK+G E E + RPF+I+P SPLMKPLLVFVNPKSGGNQG K++Q F+WYLN
Sbjct: 343 RTSFKRKASKRGMEQENKGRPFVIKPISSPLMKPLLVFVNPKSGGNQGTKVLQMFMWYLN 402
Query: 511 PRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLG 570
PRQVFDLSQ GPK+ALE+YRKV NLRILACGGDGTVGWILS LD+L+L P PPV +LPLG
Sbjct: 403 PRQVFDLSQEGPKDALELYRKVPNLRILACGGDGTVGWILSILDELQLSPQPPVGVLPLG 462
Query: 571 TGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDR 630
TGNDLARTLNWGGGYTDEPVSKIL VE+G VVQLDRW+LH E NP+ PE+ ++G +
Sbjct: 463 TGNDLARTLNWGGGYTDEPVSKILCQVEDGTVVQLDRWNLHVERNPDLPPEELEDGVC-K 521
Query: 631 LPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLA 690
LPL+VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAG AFSDFL SS+DL+
Sbjct: 522 LPLNVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLS 581
Query: 691 KHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEV 750
KH++VVCDG DLTPKIQ+LK QC+VFLNIPRYCAGTMPWG+PG+HHDFEPQRHDDGY+EV
Sbjct: 582 KHVKVVCDGTDLTPKIQELKFQCIVFLNIPRYCAGTMPWGNPGDHHDFEPQRHDDGYIEV 641
Query: 751 IGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATM 810
IGFTM SLAALQVGGHGERL QCREV+L T K+IP+QVDGEPC+LA + IRI+LRNQA M
Sbjct: 642 IGFTMASLAALQVGGHGERLHQCREVMLLTYKSIPMQVDGEPCRLAPAMIRISLRNQANM 701
Query: 811 VQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEAS----------- 859
VQK+KRR++ PL +D Q VP++LRI+V+++S+ DYE HYDKE+L+EAS
Sbjct: 702 VQKSKRRTSMPLLNDPQSVPDRLRIRVNKISLQDYEGFHYDKEKLREASISDWLRTIAGE 761
Query: 860 -------VPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSP---------------TC 897
+PLG +VV GD DLE CR +I+RLQ++ + S +
Sbjct: 762 LVQSFGAIPLGILVVRGDCDLETCRMYIDRLQEDLQSVSSGSQRVHYQDHETSFPRALSA 821
Query: 898 QKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGAS------ARPD 951
Q+LSP+WCFLD DR+QEHL++V EI+QDEI+ILDP+++ + PD
Sbjct: 822 QRLSPRWCFLD----------DRSQEHLHFVMEISQDEIFILDPDMVVSQPAGTPPGMPD 871
Query: 952 LPTPTSPLPTSPCSPTPR------SLQGDAAP---------------------PQGEELI 984
L + + +P R S G AP + ++
Sbjct: 872 LVVEQASGISDWWNPALRKRMLSDSGLGMIAPYYEDSDLKDLSHSRVLQSPVSSEDHAIL 931
Query: 985 EAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILD-AV 1043
+A D KL E ++ GG L+ + +LLH+A TG+ ++V+Y+LDH P E+LD A
Sbjct: 932 QAVIAGDLMKLIESYKNGGSLLIQGPDHCSLLHYAAKTGNGEIVKYILDHGPSELLDMAD 991
Query: 1044 EENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQ 1103
E GET LH+AA R +C +V+AGASL KTD +G TP++RA++A D +LAAYLE+RQ
Sbjct: 992 SETGETALHKAACQRNRAVCQLLVDAGASLRKTDSKGKTPQERAQQAGDPDLAAYLESRQ 1051
Query: 1104 HYQMIQREDQETAV 1117
+Y++I ED ETAV
Sbjct: 1052 NYKVIGHEDLETAV 1065
>gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens]
Length = 804
Score = 293 bits (750), Expect = 6e-79
Identities = 191/575 (33%), Positives = 276/575 (48%), Gaps = 84/575 (14%)
Query: 285 GEHIWFETNVSGDFCYVGEQYC--VARMLKSVSRRK--CAACKIVVHTPCIEQLEKINFR 340
G+H+W + + YC ML V ++ C+ CK VH C+ R
Sbjct: 243 GQHVWRLKHFNKP------AYCNLCLNMLIGVGKQGLCCSFCKYTVHERCVA-------R 289
Query: 341 CKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCK 400
PS ++ ++ R + H+WV KC C K + + + + C WC+
Sbjct: 290 APPSCIKTYVKSKRNTDVMHHYWVEGNCPT-KCDKCHKTVKCY-----QGLTGLHCVWCQ 343
Query: 401 QAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI---LRARRPQNTLKASKKKKRASFKR 457
H+K + ++ C G ++PPT I + P + + ++++ K
Sbjct: 344 ITLHNKCA----SHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKE 399
Query: 458 KSSKKGPEEGRWRPFIIRP------------TPSPLMKPLLVFVNPKSGGNQGAKIIQSF 505
KS + P + + + R TP P PLLVFVNPKSGG QG +I + F
Sbjct: 400 KSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKF 459
Query: 506 LWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVA 565
+ LNPRQV+ LS GP L +R V + R+LACGGDGTVGW+L +++ + PPVA
Sbjct: 460 QYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEKANVGKHPPVA 519
Query: 566 ILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDE 625
ILPLGTGNDLAR L WGGGY E + KIL +E + LDRW PN D+DE
Sbjct: 520 ILPLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIPN------DKDE 573
Query: 626 GATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGS 685
D +P + NNYFS+G DA + FH RE +PEKFNSR +NK +Y S+ +
Sbjct: 574 KG-DPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSAT 632
Query: 686 SKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD-------- 737
K L + + + CDG+ + + ++ + + LNIP G+ WG +
Sbjct: 633 CKKLHESVEIECDGVQI--DLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKG 690
Query: 738 --------------FEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREV 776
F Q D LEV+G A+++G G RL QC V
Sbjct: 691 SDKRTTVTDAKELKFASQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCSCV 746
Query: 777 VLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMV 811
V+ TSK++P+Q+DGEP I+I +NQA M+
Sbjct: 747 VIRTSKSLPMQIDGEPWMQTPCTIKITHKNQAPML 781
>gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens]
Length = 791
Score = 291 bits (746), Expect = 2e-78
Identities = 196/573 (34%), Positives = 277/573 (48%), Gaps = 83/573 (14%)
Query: 276 VDWSESATYGEHIW----FETNVSGDFCYVGEQYCVARMLKSVSRRK--CAACKIVVHTP 329
+D S S G H W F+ +FC++ ML V ++ C CK VH
Sbjct: 261 MDDSGSKGDGRHAWTMKHFKKPTYCNFCHI--------MLMGVRKQGLCCTYCKYTVHER 312
Query: 330 CIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSK 389
C+ R P ++ S+ R ++H WV KC C K + +
Sbjct: 313 CVS-------RNIPGCVKTYSKAKRSGEVMQHAWVEGN-SSVKCDRCHKSIKCY-----Q 359
Query: 390 EIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKK 449
+ A C WC+ +H K ++ C G ++ PT I R + K+
Sbjct: 360 SVTARHCVWCRMTFHRKC------ELSTLCDGGELRDHILLPTSICPITRDRPGEKSD-- 411
Query: 450 KKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYL 509
S KG +++ I PTP PLLV VNPKSGG QG +I++ F + L
Sbjct: 412 -------GCVSAKGELVMQYK---IIPTPG--THPLLVLVNPKSGGRQGERILRKFHYLL 459
Query: 510 NPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPL 569
NP+QVF+L GGP L +R + R+LACGGDGTVGWIL +D+ PPVA+LPL
Sbjct: 460 NPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPL 519
Query: 570 GTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATD 629
GTGNDLAR L WGGGY ++KIL +E+ +V LDRW L P E+ + G D
Sbjct: 520 GTGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPR-----EEVENG--D 572
Query: 630 RLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDL 689
++P + NNYFS+G DA + FH RE +PEKFNSR +NK++Y S+ + K L
Sbjct: 573 QVPYSIMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKL 632
Query: 690 AKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHH------------- 736
HI + CDG+ + + ++ + + LNIP GT WG ++
Sbjct: 633 HDHIELECDGVGV--DLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDP 690
Query: 737 ---DFEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPV 786
F Q D LEV+G A+++G G RL QC V + T+K +P+
Sbjct: 691 KELKFCVQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPM 746
Query: 787 QVDGEPCKLAASRIRIALRNQATMVQKAKRRSA 819
QVDGEP I+I +NQA M+ ++S+
Sbjct: 747 QVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSS 779
>gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens]
Length = 773
Score = 285 bits (729), Expect = 2e-76
Identities = 185/556 (33%), Positives = 267/556 (48%), Gaps = 84/556 (15%)
Query: 285 GEHIWFETNVSGDFCYVGEQYC--VARMLKSVSRRK--CAACKIVVHTPCIEQLEKINFR 340
G+H+W + + YC ML V ++ C+ CK VH C+ R
Sbjct: 243 GQHVWRLKHFNKP------AYCNLCLNMLIGVGKQGLCCSFCKYTVHERCVA-------R 289
Query: 341 CKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCK 400
PS ++ ++ R + H+WV KC C K + + + + C WC+
Sbjct: 290 APPSCIKTYVKSKRNTDVMHHYWVEGNCPT-KCDKCHKTVKCY-----QGLTGLHCVWCQ 343
Query: 401 QAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI---LRARRPQNTLKASKKKKRASFKR 457
H+K + ++ C G ++PPT I + P + + ++++ K
Sbjct: 344 ITLHNKCA----SHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKE 399
Query: 458 KSSKKGPEEGRWRPFIIRP------------TPSPLMKPLLVFVNPKSGGNQGAKIIQSF 505
KS + P + + + R TP P PLLVFVNPKSGG QG +I + F
Sbjct: 400 KSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKF 459
Query: 506 LWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVA 565
+ LNPRQV+ LS GP L +R V + R+LACGGDGTVGW+L +++ + PPVA
Sbjct: 460 QYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEKANVGKHPPVA 519
Query: 566 ILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDE 625
ILPLGTGNDLAR L WGGGY E + KIL +E + LDRW PN D+DE
Sbjct: 520 ILPLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIPN------DKDE 573
Query: 626 GATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGS 685
D +P + NNYFS+G DA + FH RE +PEKFNSR +NK +Y S+ +
Sbjct: 574 KG-DPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSAT 632
Query: 686 SKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD-------- 737
K L + + + CDG+ + + ++ + + LNIP G+ WG +
Sbjct: 633 CKKLHESVEIECDGVQI--DLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKG 690
Query: 738 --------------FEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREV 776
F Q D LEV+G A+++G G RL QC V
Sbjct: 691 SDKRTTVTDAKELKFASQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCSCV 746
Query: 777 VLTTSKAIPVQVDGEP 792
V+ TSK++P+Q+DGEP
Sbjct: 747 VIRTSKSLPMQIDGEP 762
>gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (713), Expect = 1e-74
Identities = 178/530 (33%), Positives = 258/530 (48%), Gaps = 67/530 (12%)
Query: 319 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGK 378
C CK VH C + P + +++ ++ H WV + G+C C K
Sbjct: 235 CNLCKYTVHDQCA-------MKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQK 287
Query: 379 GFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRAR 438
+ +HS + + C WC H ++ LQ + C G+ ++PP+ I
Sbjct: 288 KIR---IYHS--LTGLHCVWC----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY--- 335
Query: 439 RPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQG 498
+ L + +K + + S K + +R P P PLLVFVNPKSGG QG
Sbjct: 336 --PSVLASGPDRKNS---KTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQG 390
Query: 499 AKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRL 558
+++ F + LNPRQVF+L + GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L
Sbjct: 391 QRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANL 450
Query: 559 KPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEA 618
PPVA+LPLGTGNDLAR L WGGGY + ++KIL +E VV +DRW + P
Sbjct: 451 PVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP---- 506
Query: 619 GPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAF 678
+ E +D +P + NNYFS+G DA + FH RE PEKFNSR +NK++Y A
Sbjct: 507 ---QQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFAT 563
Query: 679 SDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD- 737
S+ + + K L + + V G L + +L + + LNIP G+ WG H
Sbjct: 564 SESIFSTCKKLEESLTVEICGKPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGD 621
Query: 738 ---------------FEPQ-------RHDDGYLEVIGFTMTSLAALQVG-------GHGE 768
+P D LEV+G A+++G G
Sbjct: 622 IYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGR 677
Query: 769 RLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRS 818
RL +C E+ T+K +P+Q+DGEP I+I +NQ M+ RS
Sbjct: 678 RLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (713), Expect = 1e-74
Identities = 178/530 (33%), Positives = 258/530 (48%), Gaps = 67/530 (12%)
Query: 319 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGK 378
C CK VH C + P + +++ ++ H WV + G+C C K
Sbjct: 235 CNLCKYTVHDQCA-------MKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQK 287
Query: 379 GFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRAR 438
+ +HS + + C WC H ++ LQ + C G+ ++PP+ I
Sbjct: 288 KIR---IYHS--LTGLHCVWC----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY--- 335
Query: 439 RPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQG 498
+ L + +K + + S K + +R P P PLLVFVNPKSGG QG
Sbjct: 336 --PSVLASGPDRKNS---KTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQG 390
Query: 499 AKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRL 558
+++ F + LNPRQVF+L + GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L
Sbjct: 391 QRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANL 450
Query: 559 KPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEA 618
PPVA+LPLGTGNDLAR L WGGGY + ++KIL +E VV +DRW + P
Sbjct: 451 PVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP---- 506
Query: 619 GPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAF 678
+ E +D +P + NNYFS+G DA + FH RE PEKFNSR +NK++Y A
Sbjct: 507 ---QQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFAT 563
Query: 679 SDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD- 737
S+ + + K L + + V G L + +L + + LNIP G+ WG H
Sbjct: 564 SESIFSTCKKLEESLTVEICGKPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGD 621
Query: 738 ---------------FEPQ-------RHDDGYLEVIGFTMTSLAALQVG-------GHGE 768
+P D LEV+G A+++G G
Sbjct: 622 IYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGR 677
Query: 769 RLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRS 818
RL +C E+ T+K +P+Q+DGEP I+I +NQ M+ RS
Sbjct: 678 RLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (713), Expect = 1e-74
Identities = 178/530 (33%), Positives = 258/530 (48%), Gaps = 67/530 (12%)
Query: 319 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGK 378
C CK VH C + P + +++ ++ H WV + G+C C K
Sbjct: 235 CNLCKYTVHDQCA-------MKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQK 287
Query: 379 GFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRAR 438
+ +HS + + C WC H ++ LQ + C G+ ++PP+ I
Sbjct: 288 KIR---IYHS--LTGLHCVWC----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY--- 335
Query: 439 RPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQG 498
+ L + +K + + S K + +R P P PLLVFVNPKSGG QG
Sbjct: 336 --PSVLASGPDRKNS---KTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQG 390
Query: 499 AKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRL 558
+++ F + LNPRQVF+L + GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L
Sbjct: 391 QRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANL 450
Query: 559 KPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEA 618
PPVA+LPLGTGNDLAR L WGGGY + ++KIL +E VV +DRW + P
Sbjct: 451 PVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP---- 506
Query: 619 GPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAF 678
+ E +D +P + NNYFS+G DA + FH RE PEKFNSR +NK++Y A
Sbjct: 507 ---QQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFAT 563
Query: 679 SDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD- 737
S+ + + K L + + V G L + +L + + LNIP G+ WG H
Sbjct: 564 SESIFSTCKKLEESLTVEICGKPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGD 621
Query: 738 ---------------FEPQ-------RHDDGYLEVIGFTMTSLAALQVG-------GHGE 768
+P D LEV+G A+++G G
Sbjct: 622 IYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGR 677
Query: 769 RLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRS 818
RL +C E+ T+K +P+Q+DGEP I+I +NQ M+ RS
Sbjct: 678 RLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (713), Expect = 1e-74
Identities = 178/530 (33%), Positives = 258/530 (48%), Gaps = 67/530 (12%)
Query: 319 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGK 378
C CK VH C + P + +++ ++ H WV + G+C C K
Sbjct: 235 CNLCKYTVHDQCA-------MKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQK 287
Query: 379 GFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRAR 438
+ +HS + + C WC H ++ LQ + C G+ ++PP+ I
Sbjct: 288 KIR---IYHS--LTGLHCVWC----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY--- 335
Query: 439 RPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQG 498
+ L + +K + + S K + +R P P PLLVFVNPKSGG QG
Sbjct: 336 --PSVLASGPDRKNS---KTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQG 390
Query: 499 AKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRL 558
+++ F + LNPRQVF+L + GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L
Sbjct: 391 QRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANL 450
Query: 559 KPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEA 618
PPVA+LPLGTGNDLAR L WGGGY + ++KIL +E VV +DRW + P
Sbjct: 451 PVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP---- 506
Query: 619 GPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAF 678
+ E +D +P + NNYFS+G DA + FH RE PEKFNSR +NK++Y A
Sbjct: 507 ---QQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFAT 563
Query: 679 SDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD- 737
S+ + + K L + + V G L + +L + + LNIP G+ WG H
Sbjct: 564 SESIFSTCKKLEESLTVEICGKPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGD 621
Query: 738 ---------------FEPQ-------RHDDGYLEVIGFTMTSLAALQVG-------GHGE 768
+P D LEV+G A+++G G
Sbjct: 622 IYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGR 677
Query: 769 RLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRS 818
RL +C E+ T+K +P+Q+DGEP I+I +NQ M+ RS
Sbjct: 678 RLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens]
Length = 752
Score = 270 bits (689), Expect = 7e-72
Identities = 149/365 (40%), Positives = 204/365 (55%), Gaps = 36/365 (9%)
Query: 478 PSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRI 537
P+P PLLV VNPKSGG QG +I++ F + LNP+QVF+L GGP L +R + R+
Sbjct: 389 PTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRV 448
Query: 538 LACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHV 597
LACGGDGTVGWIL +D+ PPVA+LPLGTGNDLAR L WGGGY ++KIL +
Sbjct: 449 LACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDI 508
Query: 598 EEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESRE 657
E+ +V LDRW L P E+ + G D++P + NNYFS+G DA + FH RE
Sbjct: 509 EQSPLVMLDRWHLEVIPR-----EEVENG--DQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
Query: 658 ANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFL 717
+PEKFNSR +NK++Y S+ + K L HI + CDG+ + + ++ + + L
Sbjct: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGV--DLSNIFLEGIAIL 619
Query: 718 NIPRYCAGTMPWGHPGEHH----------------DFEPQRHDDGYLEVIGFTMTSLAAL 761
NIP GT WG ++ F Q D LEV+G A+
Sbjct: 620 NIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLE----GAM 675
Query: 762 QVG-------GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKA 814
++G G RL QC V + T+K +P+QVDGEP I+I +NQA M+
Sbjct: 676 EMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGP 735
Query: 815 KRRSA 819
++S+
Sbjct: 736 PQKSS 740
>gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens]
Length = 766
Score = 253 bits (646), Expect = 7e-67
Identities = 185/573 (32%), Positives = 260/573 (45%), Gaps = 108/573 (18%)
Query: 276 VDWSESATYGEHIW----FETNVSGDFCYVGEQYCVARMLKSVSRRK--CAACKIVVHTP 329
+D S S G H W F+ +FC++ ML V ++ C CK VH
Sbjct: 261 MDDSGSKGDGRHAWTMKHFKKPTYCNFCHI--------MLMGVRKQGLCCTYCKYTVHER 312
Query: 330 CIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSK 389
C+ R P ++ S+ R ++H WV KC C K + +
Sbjct: 313 CVS-------RNIPGCVKTYSKAKRSGEVMQHAWVEGN-SSVKCDRCHKSIKCY-----Q 359
Query: 390 EIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKK 449
+ A C WC+ +H K ++ C G ++ PT I R + K+
Sbjct: 360 SVTARHCVWCRMTFHRKC------ELSTLCDGGELRDHILLPTSICPITRDRPGEKSD-- 411
Query: 450 KKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYL 509
S KG +++ I PTP PLLV VNPKSGG QG
Sbjct: 412 -------GCVSAKGELVMQYK---IIPTPG--THPLLVLVNPKSGGRQG----------- 448
Query: 510 NPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPL 569
E L +R + R+LACGGDGTVGWIL +D+ PPVA+LPL
Sbjct: 449 --------------ERLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPL 494
Query: 570 GTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATD 629
GTGNDLAR L WGGGY ++KIL +E+ +V LDRW L P E+ + G D
Sbjct: 495 GTGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPR-----EEVENG--D 547
Query: 630 RLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDL 689
++P + NNYFS+G DA + FH RE +PEKFNSR +NK++Y S+ + K L
Sbjct: 548 QVPYSIMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKL 607
Query: 690 AKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHH------------- 736
HI + CDG+ + + ++ + + LNIP GT WG ++
Sbjct: 608 HDHIELECDGVGV--DLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDP 665
Query: 737 ---DFEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPV 786
F Q D LEV+G A+++G G RL QC V + T+K +P+
Sbjct: 666 KELKFCVQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPM 721
Query: 787 QVDGEPCKLAASRIRIALRNQATMVQKAKRRSA 819
QVDGEP I+I +NQA M+ ++S+
Sbjct: 722 QVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSS 754
>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
Length = 942
Score = 238 bits (606), Expect = 3e-62
Identities = 147/373 (39%), Positives = 205/373 (54%), Gaps = 21/373 (5%)
Query: 471 PFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYR 530
P ++ P PLLVFVNPKSGG +G ++ SF LNP QVFDL+ GGP L ++
Sbjct: 575 PDLLHAKLPPDSCPLLVFVNPKSGGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFS 634
Query: 531 KVHNLRILACGGDGTVGWILSTLDQLRLK---PPPPVAILPLGTGNDLARTLNWGGGYTD 587
+V R+L CGGDGTVGW+L L++ R + P P VAILPLGTGNDL R L WG GY+
Sbjct: 635 QVPCFRVLVCGGDGTVGWVLGALEETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSG 694
Query: 588 EPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAH 647
E +L V+E + V +DRW + + + EAG + D + + +NY +G DA
Sbjct: 695 EDPFSVLLSVDEADAVLMDRWTILLDAH-EAGSAENDTADAEPPKIVQMSNYCGIGIDAE 753
Query: 648 VTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDL-TPKI 706
++L+FH++RE P KF SR NK Y + S+ L K IR+ + ++ P I
Sbjct: 754 LSLDFHQAREEEPGKFTSRLHNKGVYVRVGLQK--ISHSRSLHKQIRLQVERQEVELPSI 811
Query: 707 QDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFT-MTSLAALQVG- 764
+ L +F+NIP + +G WG + FE R DDG LEV+G T + + +Q G
Sbjct: 812 EGL-----IFINIPSWGSGADLWGSDSDTR-FEKPRMDDGLLEVVGVTGVVHMGQVQGGL 865
Query: 765 GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRI-ALRNQATMVQKAKRR-----S 818
G R+ Q +T KA PVQVDGEP A + I A + M++KAK++ +
Sbjct: 866 RSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGHMIISAAGPKVHMLRKAKQKPRRAGT 925
Query: 819 AAPLHSDQQPVPE 831
+D P PE
Sbjct: 926 TRDARADAAPAPE 938
>gi|4503313 diacylglycerol kinase epsilon [Homo sapiens]
Length = 567
Score = 216 bits (550), Expect = 1e-55
Identities = 163/541 (30%), Positives = 261/541 (48%), Gaps = 71/541 (13%)
Query: 286 EHIWFETNVSGD--FCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKP 343
+H W +T++ +C V C +L+ C C + V C+ + +K F+CK
Sbjct: 59 KHGWRDTDLFSQPTYCCV----CAQHILQGAF---CDCCGLRVDEGCLRKADK-RFQCKE 110
Query: 344 SFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAY 403
++ ++ + + HHW+ R C +C QQ ++ C WC++
Sbjct: 111 IMLKNDTKVLDA---MPHHWI--RGNVPLCSYCMVCKQQCGC--QPKLCDYRCIWCQKTV 163
Query: 404 HSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKG 463
H + C E C G ++IPP+++ ++ +K K+ ++ +SK G
Sbjct: 164 HDE--CMKNSLKNEKCDFGEFKNLIIPPSYL-------TSINQMRKDKKTDYEVLASKLG 214
Query: 464 PEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPK 523
+ W P L++ N +SG N G ++ F LNP QVFD+++ P
Sbjct: 215 KQ---WTP-------------LIILANSRSGTNMGEGLLGEFRILLNPVQVFDVTKTPPI 258
Query: 524 EALEMYRKV--HNLRILACGGDGTVGWILSTLDQLRLKPP----PPVAILPLGTGNDLAR 577
+AL++ + ++ R+L CGGDGTVGW+L +D +++K P VA+LPLGTGNDL+
Sbjct: 259 KALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIKGQEKYIPQVAVLPLGTGNDLSN 318
Query: 578 TLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATD-RLPLD- 634
TL WG GY E PV+++L +V E + ++LDRW + ++G + R P +
Sbjct: 319 TLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVT----------NKGYYNLRKPKEF 368
Query: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
NNYFS+G DA + L FH RE P F+SR NK Y D L+ KDL K +
Sbjct: 369 TMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKVE 428
Query: 695 VVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIG- 752
+ DG + P ++ ++ LNI + G W G+ + RHDDG LEV+G
Sbjct: 429 LELDGERVALPSLEG-----IIVLNIGYWGGGCRLWEGMGD-ETYPLARHDDGLLEVVGV 482
Query: 753 FTMTSLAALQVG-GHGERLTQCREV-VLTTSKAIPVQVDGEPCKLAASRIRIALRNQATM 810
+ A +QV + R+ Q V ++ +P+QVDGEP + I + A M
Sbjct: 483 YGSFHCAQIQVKLANPFRIGQAHTVRLILKCSMMPMQVDGEPWAQGPCTVTITHKTHAMM 542
Query: 811 V 811
+
Sbjct: 543 L 543
>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
Length = 1164
Score = 152 bits (383), Expect = 2e-36
Identities = 108/333 (32%), Positives = 146/333 (43%), Gaps = 54/333 (16%)
Query: 285 GEHIWFE-TNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKP 343
G H W+ ++ FC V + +S C CK H C + CK
Sbjct: 174 GMHNWYACSHARPTFCNVCRESLSGVTSHGLS---CEVCKFKAHKRCAVRATN---NCKW 227
Query: 344 SFRESGSRNVREP---TFVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISCSWC 399
+ S +++ E + H W+ KC C K + C WC
Sbjct: 228 TTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWK-----CLWC 282
Query: 400 KQAYHSKVSCFMLQQIEEP-CSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRK 458
K H+ +C + + P C LG +IPP +
Sbjct: 283 KTMVHT--AC---KDLYHPICPLGQCKVSIIPPIAL----------------------NS 315
Query: 459 SSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLS 518
+ G R T S + PLLVFVN KSG NQG K ++ F LNP QVFDL
Sbjct: 316 TDSDG---------FCRATFSFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLM 366
Query: 519 QGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLART 578
GGP L +++K N RIL CGGDG+VGW+LS +D+L L + +LPLGTGNDLAR
Sbjct: 367 NGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQLGVLPLGTGNDLARV 426
Query: 579 LNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDL 610
L WGG Y D+ + +IL +E + LDRW +
Sbjct: 427 LGWGGSYDDDTQLPQILEKLERASTKMLDRWSI 459
Score = 105 bits (262), Expect = 2e-22
Identities = 65/184 (35%), Positives = 94/184 (51%), Gaps = 10/184 (5%)
Query: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
V NNYF +G DA ++LEF+ RE +PEK SR +N M+Y + L S K+L + ++
Sbjct: 770 VMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQ 829
Query: 695 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 753
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 830 LECDGQYIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAI 884
Query: 754 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 809
+M + + R+ QCR V +T + +PVQVDGE I+I +N+A
Sbjct: 885 FDSMQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQ 944
Query: 810 MVQK 813
M+ +
Sbjct: 945 MLTR 948
>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
Length = 1220
Score = 152 bits (383), Expect = 2e-36
Identities = 108/333 (32%), Positives = 146/333 (43%), Gaps = 54/333 (16%)
Query: 285 GEHIWFE-TNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKP 343
G H W+ ++ FC V + +S C CK H C + CK
Sbjct: 174 GMHNWYACSHARPTFCNVCRESLSGVTSHGLS---CEVCKFKAHKRCAVRATN---NCKW 227
Query: 344 SFRESGSRNVREP---TFVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISCSWC 399
+ S +++ E + H W+ KC C K + C WC
Sbjct: 228 TTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWK-----CLWC 282
Query: 400 KQAYHSKVSCFMLQQIEEP-CSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRK 458
K H+ +C + + P C LG +IPP +
Sbjct: 283 KTMVHT--AC---KDLYHPICPLGQCKVSIIPPIAL----------------------NS 315
Query: 459 SSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLS 518
+ G R T S + PLLVFVN KSG NQG K ++ F LNP QVFDL
Sbjct: 316 TDSDG---------FCRATFSFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLM 366
Query: 519 QGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLART 578
GGP L +++K N RIL CGGDG+VGW+LS +D+L L + +LPLGTGNDLAR
Sbjct: 367 NGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQLGVLPLGTGNDLARV 426
Query: 579 LNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDL 610
L WGG Y D+ + +IL +E + LDRW +
Sbjct: 427 LGWGGSYDDDTQLPQILEKLERASTKMLDRWSI 459
Score = 105 bits (262), Expect = 2e-22
Identities = 65/184 (35%), Positives = 94/184 (51%), Gaps = 10/184 (5%)
Query: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
V NNYF +G DA ++LEF+ RE +PEK SR +N M+Y + L S K+L + ++
Sbjct: 770 VMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQ 829
Query: 695 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 753
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 830 LECDGQYIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAI 884
Query: 754 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 809
+M + + R+ QCR V +T + +PVQVDGE I+I +N+A
Sbjct: 885 FDSMQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQ 944
Query: 810 MVQK 813
M+ +
Sbjct: 945 MLTR 948
>gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo
sapiens]
Length = 1170
Score = 150 bits (379), Expect = 6e-36
Identities = 100/299 (33%), Positives = 133/299 (44%), Gaps = 47/299 (15%)
Query: 319 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCR 374
C CK H C + CK + S +++ E + H W+ KC
Sbjct: 150 CEVCKFKAHKRCAVRATN---NCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCT 206
Query: 375 HCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI 434
C K C WCK H+ +L + C LG+ VIPPT +
Sbjct: 207 VCDKTCGSVLRLQDWR-----CLWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL 257
Query: 435 LRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSG 494
N++ + +G W+ P PLLVFVN KSG
Sbjct: 258 -------NSIDS-------------------DGFWKA----SCPPSCTSPLLVFVNSKSG 287
Query: 495 GNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLD 554
NQG K ++ F LNP QVFDL GGP L +++K RIL CGGDG+VGW+LS +D
Sbjct: 288 DNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEID 347
Query: 555 QLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 612
L L + +LPLGTGNDLAR L WG D+ + +IL +E + LDRW + A
Sbjct: 348 SLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 406
Score = 99.4 bits (246), Expect = 2e-20
Identities = 78/279 (27%), Positives = 124/279 (44%), Gaps = 25/279 (8%)
Query: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 719 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 778
Query: 695 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 753
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 779 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 833
Query: 754 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 808
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 834 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 893
Query: 809 TMVQKAKRRSAAPLHSDQQ----PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGT 864
T+ + S D+Q P P S+H + Q+ + G
Sbjct: 894 TLTRDRAFESTLKSWEDKQKCELPRPPS-------CSLHPEMLSEEEATQMDQFGQAAGV 946
Query: 865 VVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 903
++ S E+ ++H + Q+ A S + ++ K
Sbjct: 947 LI---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 982
>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
sapiens]
Length = 1214
Score = 150 bits (379), Expect = 6e-36
Identities = 100/299 (33%), Positives = 133/299 (44%), Gaps = 47/299 (15%)
Query: 319 CAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCR 374
C CK H C + CK + S +++ E + H W+ KC
Sbjct: 194 CEVCKFKAHKRCAVRATN---NCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCT 250
Query: 375 HCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI 434
C K C WCK H+ +L + C LG+ VIPPT +
Sbjct: 251 VCDKTCGSVLRLQDWR-----CLWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL 301
Query: 435 LRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSG 494
N++ + +G W+ P PLLVFVN KSG
Sbjct: 302 -------NSIDS-------------------DGFWKA----SCPPSCTSPLLVFVNSKSG 331
Query: 495 GNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLD 554
NQG K ++ F LNP QVFDL GGP L +++K RIL CGGDG+VGW+LS +D
Sbjct: 332 DNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEID 391
Query: 555 QLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 612
L L + +LPLGTGNDLAR L WG D+ + +IL +E + LDRW + A
Sbjct: 392 SLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 450
Score = 99.4 bits (246), Expect = 2e-20
Identities = 78/279 (27%), Positives = 124/279 (44%), Gaps = 25/279 (8%)
Query: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
Query: 695 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 753
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 823 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 877
Query: 754 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 808
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 878 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 937
Query: 809 TMVQKAKRRSAAPLHSDQQ----PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGT 864
T+ + S D+Q P P S+H + Q+ + G
Sbjct: 938 TLTRDRAFESTLKSWEDKQKCELPRPPS-------CSLHPEMLSEEEATQMDQFGQAAGV 990
Query: 865 VVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 903
++ S E+ ++H + Q+ A S + ++ K
Sbjct: 991 LI---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 1026
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 134 bits (336), Expect = 6e-31
Identities = 78/226 (34%), Positives = 107/226 (47%), Gaps = 28/226 (12%)
Query: 396 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF 455
C WC H ++ + C H + VIPPT + + + +S
Sbjct: 430 CLWCNSTVHDDCR----RRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSD------- 478
Query: 456 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF 515
F S PLL+F+N KSG +QG ++ F YLNP QVF
Sbjct: 479 ----------------FWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVF 522
Query: 516 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL 575
DL +GGP+ L M++ RIL CGGDG+V W+LS +D L +A++PLGTGNDL
Sbjct: 523 DLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDL 582
Query: 576 ARTLNWGGGYT-DEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGP 620
AR L WG + + IL+ VE+ +V LDRW + P P
Sbjct: 583 ARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTP 628
Score = 110 bits (275), Expect = 7e-24
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 16/223 (7%)
Query: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
V NNYF +G DA ++L+F+ R+ +P ++NSR +NKM+Y + L S + L + +
Sbjct: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
Query: 695 VVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 753
+ CDG ++ P +Q +V LNI Y G WG ++E DDG LEV+
Sbjct: 917 LECDGETISLPNLQG-----IVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAI 971
Query: 754 TMTSLAALQ--VGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 809
+ A+ + H R+ QC EV++T + IPVQVDGE I+I +N A
Sbjct: 972 FGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQ 1031
Query: 810 MVQKAK-----RRSAAPLHSDQQPVPE-QLRIQVSRVSMHDYE 846
M+ + + + H++ Q P+ QL Q S+ S+ D E
Sbjct: 1032 MLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEE 1074
>gi|223634006 hypothetical protein LOC441869 [Homo sapiens]
Length = 399
Score = 57.4 bits (137), Expect = 7e-08
Identities = 41/117 (35%), Positives = 54/117 (46%), Gaps = 2/117 (1%)
Query: 983 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDA 1042
L++A R + +L R G + RD RT LH AV G +VR LL P + A
Sbjct: 45 LLQAVWRGPAGLVTQLLRQGASVEERDHAGRTPLHLAVLRGHAPLVRLLLQRGAP--VGA 102
Query: 1043 VEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
V+ G T LH+AA G + +++ GAS G TP A T LAA L
Sbjct: 103 VDRAGRTALHEAAWHGHSRVAELLLQRGASAAARSGTGLTPLHWAAALGHTLLAARL 159
Score = 43.5 bits (101), Expect = 0.001
Identities = 38/121 (31%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
Query: 983 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDH-APPEILD 1041
L+ AA L+ L G + RD T L A + G + LL H A P I D
Sbjct: 207 LLVAAAAGRGAALRFLLARGARVDARDGAGATALGLAAALGRSQDIEVLLGHGADPGIRD 266
Query: 1042 AVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLEN 1101
+G + LH+AAA G +V GA + D G TP A + E+A L +
Sbjct: 267 ---RHGRSALHRAAARGHLLAVQLLVTQGAEVDARDTLGLTPLHHASREGHVEVAGCLLD 323
Query: 1102 R 1102
R
Sbjct: 324 R 324
Score = 32.3 bits (72), Expect = 2.6
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 1002 GGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRT 1061
G D RD R+ LH A + G V+ L+ +DA + G T LH A+ G
Sbjct: 259 GADPGIRDRHGRSALHRAAARGHLLAVQLLVTQGAE--VDARDTLGLTPLHHASREGHVE 316
Query: 1062 ICHYIVEAGASLMKTDQQGDTP 1083
+ +++ GA + T TP
Sbjct: 317 VAGCLLDRGAQVDATGWLRKTP 338
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 53.5 bits (127), Expect = 1e-06
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
Query: 981 EELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDH-APPEI 1039
+ L ++A ND +Q+L G D D++ RT LH A G+ +V+ LLDH A P
Sbjct: 112 KRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQ 171
Query: 1040 LDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 1088
D + G T LH AA + ++ GA + D+ G TP A+
Sbjct: 172 RDGL---GNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAK 217
>gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 2 [Homo sapiens]
Length = 1390
Score = 53.1 bits (126), Expect = 1e-06
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 2/114 (1%)
Query: 986 AAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEE 1045
AA++ + ++ L G D+ D+Q RT L A G V +LL L ++++
Sbjct: 1111 AARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAA--LSSLDK 1168
Query: 1046 NGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
G + L A G R + Y+VE GA++ +TD+ G TP A D E YL
Sbjct: 1169 EGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYL 1222
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 983 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDA 1042
L+ AA ++ L G L D++ + L A G + VV+YL++ +D
Sbjct: 1141 LMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAA--IDQ 1198
Query: 1043 VEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
++NG T L AA G Y+VE GA + D G P RA ++T + L
Sbjct: 1199 TDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVAL 1255
Score = 32.0 bits (71), Expect = 3.4
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 43/129 (33%)
Query: 998 LHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLL----------------DHAPPEILD 1041
L + G + H D++ + L H+ G D+++YLL HA + L
Sbjct: 979 LTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALT 1038
Query: 1042 A---------------------VEENG------ETCLHQAAALGQRTICHYIVEAGASLM 1074
A VE NG ET L AA G+ +C ++ GA++
Sbjct: 1039 AAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVS 1098
Query: 1075 KTDQQGDTP 1083
+T+++G P
Sbjct: 1099 RTNRRGVPP 1107
Score = 30.4 bits (67), Expect = 9.8
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 1023 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG 1080
G ++VV LL+ LD ENG T L AAA G + + + G + D++G
Sbjct: 938 GHEEVVTLLLEFGA--CLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKG 993
>gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 1 [Homo sapiens]
Length = 1861
Score = 53.1 bits (126), Expect = 1e-06
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 2/114 (1%)
Query: 986 AAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEE 1045
AA++ + ++ L G D+ D+Q RT L A G V +LL L ++++
Sbjct: 1119 AARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAA--LSSLDK 1176
Query: 1046 NGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
G + L A G R + Y+VE GA++ +TD+ G TP A D E YL
Sbjct: 1177 EGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYL 1230
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 983 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDA 1042
L+ AA ++ L G L D++ + L A G + VV+YL++ +D
Sbjct: 1149 LMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAA--IDQ 1206
Query: 1043 VEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
++NG T L AA G Y+VE GA + D G P RA ++T + L
Sbjct: 1207 TDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVAL 1263
Score = 32.0 bits (71), Expect = 3.4
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 43/129 (33%)
Query: 998 LHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLL----------------DHAPPEILD 1041
L + G + H D++ + L H+ G D+++YLL HA + L
Sbjct: 987 LTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALT 1046
Query: 1042 A---------------------VEENG------ETCLHQAAALGQRTICHYIVEAGASLM 1074
A VE NG ET L AA G+ +C ++ GA++
Sbjct: 1047 AAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVS 1106
Query: 1075 KTDQQGDTP 1083
+T+++G P
Sbjct: 1107 RTNRRGVPP 1115
Score = 30.4 bits (67), Expect = 9.8
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 1023 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG 1080
G ++VV LL+ LD ENG T L AAA G + + + G + D++G
Sbjct: 946 GHEEVVTLLLEFGA--CLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKG 1001
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 50.8 bits (120), Expect = 7e-06
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Query: 980 GEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEI 1039
G + A D ++ +L G D+ + + T LH A + D+V++L+++
Sbjct: 41 GAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGAN-- 98
Query: 1040 LDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
++ + G LH AA+ G I +++ GA + + +GDTP AE+ EL
Sbjct: 99 INQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNE 158
Query: 1100 ENRQ 1103
NRQ
Sbjct: 159 VNRQ 162
Score = 33.5 bits (75), Expect = 1.2
Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 12/140 (8%)
Query: 979 QGEELIEAAKRNDFCKLQELHR---AG--GDLMHRDEQSRTLLHHAVSTGSKDVVRYLLD 1033
QG ++ A K + L++ + +G D+ H + T LH A + G +V++ L+
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQ 220
Query: 1034 HAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDT 1093
++ + +G T LH AA G+ C +V+ + ++ G T A D
Sbjct: 221 AGYD--VNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQT----AFDVADE 274
Query: 1094 ELAAYLENRQHYQMIQREDQ 1113
++ YLE Q Q + ++
Sbjct: 275 DILGYLEELQKKQNLLHSEK 294
Score = 32.0 bits (71), Expect = 3.4
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 23/111 (20%)
Query: 981 EELIEAAKRNDFCKLQELHRAGGDL-MHRDEQSRTLLHHA---VSTGSKDVVRYLLDHAP 1036
EE +E +N E++R G D+ R E+ R +L A +++G + VR+
Sbjct: 148 EEAMEELLQN------EVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA----- 196
Query: 1037 PEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRA 1087
++G T LH AAA G + +++AG + D G TP A
Sbjct: 197 --------KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAA 239
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
isoform a [Homo sapiens]
Length = 1030
Score = 50.8 bits (120), Expect = 7e-06
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Query: 980 GEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEI 1039
G + A D ++ +L G D+ + + T LH A + D+V++L+++
Sbjct: 41 GAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGAN-- 98
Query: 1040 LDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
++ + G LH AA+ G I +++ GA + + +GDTP AE+ EL
Sbjct: 99 INQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNE 158
Query: 1100 ENRQ 1103
NRQ
Sbjct: 159 VNRQ 162
Score = 33.5 bits (75), Expect = 1.2
Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 12/140 (8%)
Query: 979 QGEELIEAAKRNDFCKLQELHR---AG--GDLMHRDEQSRTLLHHAVSTGSKDVVRYLLD 1033
QG ++ A K + L++ + +G D+ H + T LH A + G +V++ L+
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQ 220
Query: 1034 HAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDT 1093
++ + +G T LH AA G+ C +V+ + ++ G T A D
Sbjct: 221 AGYD--VNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQT----AFDVADE 274
Query: 1094 ELAAYLENRQHYQMIQREDQ 1113
++ YLE Q Q + ++
Sbjct: 275 DILGYLEELQKKQNLLHSEK 294
Score = 32.0 bits (71), Expect = 3.4
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 23/111 (20%)
Query: 981 EELIEAAKRNDFCKLQELHRAGGDL-MHRDEQSRTLLHHA---VSTGSKDVVRYLLDHAP 1036
EE +E +N E++R G D+ R E+ R +L A +++G + VR+
Sbjct: 148 EEAMEELLQN------EVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA----- 196
Query: 1037 PEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRA 1087
++G T LH AAA G + +++AG + D G TP A
Sbjct: 197 --------KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAA 239
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 50.4 bits (119), Expect = 9e-06
Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 11/155 (7%)
Query: 943 LLGASARPDLP--TPTSPLPTSPC---SPTPRSLQGDAAPPQGEE----LIEAAKRNDFC 993
L+ +AR + P TP P T+P +P+ S Q D + E L AA R D
Sbjct: 117 LMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVK 176
Query: 994 KLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQ 1053
+++EL G ++ +D T LH A + G DV + L+ +++ +T LH
Sbjct: 177 QVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDD--DTPLHD 234
Query: 1054 AAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 1088
+A+ G R I ++ G + + ++ G+ P AE
Sbjct: 235 SASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAE 269
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 50.4 bits (119), Expect = 9e-06
Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 11/155 (7%)
Query: 943 LLGASARPDLP--TPTSPLPTSPC---SPTPRSLQGDAAPPQGEE----LIEAAKRNDFC 993
L+ +AR + P TP P T+P +P+ S Q D + E L AA R D
Sbjct: 140 LMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVK 199
Query: 994 KLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQ 1053
+++EL G ++ +D T LH A + G DV + L+ +++ +T LH
Sbjct: 200 QVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDD--DTPLHD 257
Query: 1054 AAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 1088
+A+ G R I ++ G + + ++ G+ P AE
Sbjct: 258 SASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAE 292
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 50.4 bits (119), Expect = 9e-06
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 11/131 (8%)
Query: 971 LQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSR--TLLHHAVSTGSKDVV 1028
L+GDAA L++AAK+ ++Q+L ++ RD Q R T LH A + +V
Sbjct: 801 LRGDAA------LLDAAKKGCLARVQKLCTPE-NINCRDTQGRNSTPLHLAAGYNNLEVA 853
Query: 1029 RYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 1088
YLL+H ++A ++ G LH AA+ G I +++ + TD+ TP A
Sbjct: 854 EYLLEHGAD--VNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAA 911
Query: 1089 KAQDTELAAYL 1099
+ T+L A L
Sbjct: 912 QKGRTQLCALL 922
Score = 48.1 bits (113), Expect = 5e-05
Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 12/177 (6%)
Query: 919 DRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPP 978
+ Q+ L+ T I ++ D LL AS DL T + + R L+G + P
Sbjct: 633 EAVQQILSESTPIRTSDV---DYRLLEASKAGDLETVKQLCSSQ--NVNCRDLEGRHSTP 687
Query: 979 QGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPE 1038
L AA N ++ L G D+ +D+ LH+A S G +V L+ H
Sbjct: 688 ----LHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS- 742
Query: 1039 ILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTEL 1095
++ + T LH+AAA G+ IC +++ GA K ++ G+TP K DT++
Sbjct: 743 -VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDI 797
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
Query: 969 RSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVV 1028
R QG + P L AA N+ + L G D+ +D+ LH+A S G D+
Sbjct: 831 RDTQGRNSTP----LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIA 886
Query: 1029 RYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTP 1083
L+ + ++A ++ T LH+AA G+ +C ++ GA +Q+G TP
Sbjct: 887 ALLIKYNT--CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTP 939
Score = 40.8 bits (94), Expect = 0.007
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Query: 998 LHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAAL 1057
L R G ++ +++ T LH A DV+ L H ++A++ G+T LH+AA
Sbjct: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK--MNALDTLGQTALHRAALA 601
Query: 1058 GQRTICHYIVEAGASLMKTDQQGDTPRQRAEKA 1090
G C ++ G+ QG T Q +A
Sbjct: 602 GHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEA 634
Score = 40.0 bits (92), Expect = 0.012
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 5/119 (4%)
Query: 983 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSR--TLLHHAVSTGSKDVVRYLLDHAPPEIL 1040
L+EA+K D +++L + ++ RD + R T LH A VV YLL H +
Sbjct: 654 LLEASKAGDLETVKQLC-SSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGAD--V 710
Query: 1041 DAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 1099
A ++ G LH A + G + +V GAS+ D TP A E+ L
Sbjct: 711 HAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLL 769
Score = 38.5 bits (88), Expect = 0.036
Identities = 41/159 (25%), Positives = 63/159 (39%), Gaps = 28/159 (17%)
Query: 954 TPTSPLPTSPCSP------TPRSLQGDAAPPQG-----------------EELIEAAKRN 990
+PTS +SP SP +P + + P G EL+EA +
Sbjct: 134 SPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVSGALRELLEACRNG 193
Query: 991 DFCKLQELHRAGGDLMHRDEQSR--TLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGE 1048
D +++ L A ++ +D R + LH A G KDVV +LL + A ++ G
Sbjct: 194 DVSRVKRLVDAA-NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGAN--VHARDDGGL 250
Query: 1049 TCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRA 1087
LH A + G + ++ GA D TP A
Sbjct: 251 IPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEA 289
Score = 35.0 bits (79), Expect = 0.40
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 986 AAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEE 1045
AA N +Q L + G D+ +D+ LH+A S G +V LL H ++A++
Sbjct: 376 AAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG--ACVNAMDL 433
Query: 1046 NGETCLHQAAALGQRTICHYIVEAGA 1071
T LH+AA+ + +C ++ GA
Sbjct: 434 WQFTPLHEAASKNRVEVCSLLLSHGA 459
Score = 33.9 bits (76), Expect = 0.89
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 995 LQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLL-DHAPPEILDAVEENGETCLHQ 1053
++ L + G ++ RD+ LH+A S G +VV LL A P +A + T LH+
Sbjct: 232 VEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADP---NARDNWNYTPLHE 288
Query: 1054 AAALGQRTICHYIVEAGA 1071
AA G+ +C +++ GA
Sbjct: 289 AAIKGKIDVCIVLLQHGA 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,610,030
Number of Sequences: 37866
Number of extensions: 2784141
Number of successful extensions: 24056
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 372
Number of HSP's successfully gapped in prelim test: 566
Number of HSP's that attempted gapping in prelim test: 17413
Number of HSP's gapped (non-prelim): 6456
length of query: 1117
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1004
effective length of database: 13,968,660
effective search space: 14024534640
effective search space used: 14024534640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.