Guide to the Human Genome
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Search of human proteins with 157502165

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157502165 family with sequence similarity 58 member B [Homo
sapiens]
         (252 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157502165 family with sequence similarity 58 member B [Homo s...   512   e-145
gi|196049382 family with sequence similarity 58, member A isofor...   415   e-116
gi|196049384 family with sequence similarity 58, member A isofor...   370   e-103
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         92   6e-19
gi|38176158 cyclin K isoform 2 [Homo sapiens]                          92   6e-19
gi|88758580 cyclin L2 isoform A [Homo sapiens]                         84   2e-16
gi|9945320 cyclin L1 [Homo sapiens]                                    81   8e-16
gi|17978469 cyclin T2 isoform b [Homo sapiens]                         78   8e-15
gi|4502629 cyclin T2 isoform a [Homo sapiens]                          78   8e-15
gi|17978466 cyclin T1 [Homo sapiens]                                   69   5e-12
gi|221554516 cyclin L2 isoform C [Homo sapiens]                        64   1e-10
gi|221554518 cyclin L2 isoform D [Homo sapiens]                        64   2e-10
gi|88758578 cyclin L2 isoform B [Homo sapiens]                         64   2e-10
gi|61676091 cyclin C isoform a [Homo sapiens]                          57   2e-08
gi|4502623 cyclin H [Homo sapiens]                                     45   6e-05
gi|61676093 cyclin C isoform b [Homo sapiens]                          38   0.010
gi|38373682 pleckstrin homology domain containing family G membe...    31   0.90 
gi|111154084 pleckstrin homology domain containing family G memb...    31   0.90 
gi|111154088 pleckstrin homology domain containing family G memb...    31   0.90 
gi|111154080 pleckstrin homology domain containing family G memb...    31   0.90 
gi|111154078 pleckstrin homology domain containing family G memb...    31   0.90 
gi|41352697 centromere protein I [Homo sapiens]                        30   2.6  
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    28   5.8  
gi|94680985 cyclin J-like [Homo sapiens]                               28   7.6  

>gi|157502165 family with sequence similarity 58 member B [Homo
           sapiens]
          Length = 252

 Score =  512 bits (1319), Expect = e-145
 Identities = 252/252 (100%), Positives = 252/252 (100%)

Query: 1   MEGMEDAGEEAGEDAGEDAREGAAAPAARVHFRVARFIMEAGVKLGMQSIPIATACTIYP 60
           MEGMEDAGEEAGEDAGEDAREGAAAPAARVHFRVARFIMEAGVKLGMQSIPIATACTIYP
Sbjct: 1   MEGMEDAGEEAGEDAGEDAREGAAAPAARVHFRVARFIMEAGVKLGMQSIPIATACTIYP 60

Query: 61  KFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWE 120
           KFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWE
Sbjct: 61  KFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWE 120

Query: 121 LRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRD 180
           LRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRD
Sbjct: 121 LRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRD 180

Query: 181 SYHGGLCLRFQAQHIAVVVLYLALQVYGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSD 240
           SYHGGLCLRFQAQHIAVVVLYLALQVYGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSD
Sbjct: 181 SYHGGLCLRFQAQHIAVVVLYLALQVYGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSD 240

Query: 241 LIQIYTIDTEIP 252
           LIQIYTIDTEIP
Sbjct: 241 LIQIYTIDTEIP 252


>gi|196049382 family with sequence similarity 58, member A isoform 1
           [Homo sapiens]
          Length = 248

 Score =  415 bits (1067), Expect = e-116
 Identities = 209/247 (84%), Positives = 217/247 (87%)

Query: 6   DAGEEAGEDAGEDAREGAAAPAARVHFRVARFIMEAGVKLGMQSIPIATACTIYPKFFCE 65
           +A E  G        EG  AP ARVHFRVARFIMEAGVKLGM+SIPIATACTIY KFFCE
Sbjct: 2   EAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCE 61

Query: 66  TILDAFDPYLIAMSSIYLAGKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWELRDSI 125
           T LDA+DPYLIAMSSIYLAGKVEEQ L   DII+VSNRYFNPS EPL LDSR WELRDSI
Sbjct: 62  TNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSI 121

Query: 126 VQRELLMLRVLRFQVSFQHPHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGG 185
           VQ ELLMLRVLRFQVSFQHPHKYLL+YLVSL+NWLN HSWQRTPVAVTAWALLRDSYHG 
Sbjct: 122 VQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGA 181

Query: 186 LCLRFQAQHIAVVVLYLALQVYGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIY 245
           LCLRFQAQHIAV VLYLALQVYGVEVPAEVEAEK WWQ F+DDLTKPIID IVSDLIQIY
Sbjct: 182 LCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQIY 241

Query: 246 TIDTEIP 252
           T+DTEIP
Sbjct: 242 TMDTEIP 248


>gi|196049384 family with sequence similarity 58, member A isoform 2
           [Homo sapiens]
          Length = 228

 Score =  370 bits (951), Expect = e-103
 Identities = 192/247 (77%), Positives = 199/247 (80%), Gaps = 20/247 (8%)

Query: 6   DAGEEAGEDAGEDAREGAAAPAARVHFRVARFIMEAGVKLGMQSIPIATACTIYPKFFCE 65
           +A E  G        EG  AP ARVHFRVARFIMEAGVKLGM+SIPIATACTIY KFFCE
Sbjct: 2   EAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCE 61

Query: 66  TILDAFDPYLIAMSSIYLAGKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWELRDSI 125
           T LDA+DPYLIAMSSIYLAGKVEEQ L   DII+VSNRYFNPS EPL LDSR WELRDSI
Sbjct: 62  TNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDSI 121

Query: 126 VQRELLMLRVLRFQVSFQHPHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGG 185
           VQ ELLMLRVLRFQVSFQHPHKYLL+YLVSL+NWLN HSWQRTPVAVTAWALLRDSYHG 
Sbjct: 122 VQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGA 181

Query: 186 LCLRFQAQHIAVVVLYLALQVYGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIY 245
           LCLRFQAQHIAV VLYLALQVYGVEVPAEVEAEK WWQ                    IY
Sbjct: 182 LCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQ--------------------IY 221

Query: 246 TIDTEIP 252
           T+DTEIP
Sbjct: 222 TMDTEIP 228


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 91.7 bits (226), Expect = 6e-19
 Identities = 59/224 (26%), Positives = 106/224 (47%), Gaps = 10/224 (4%)

Query: 25  APAARVHFRVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLA 84
           A  AR     ARFI + G +LG+    +AT    + +F+       F  Y+     ++LA
Sbjct: 44  ATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLA 103

Query: 85  GKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQH 144
           GKVEE P    DII  +    N        D    + ++ ++  E ++L+ ++F +  +H
Sbjct: 104 GKVEETPKKCKDIIKTARSLLNDVQFGQFGD----DPKEEVMVLERILLQTIKFDLQVEH 159

Query: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLAL 204
           P+++LL Y   LK   N    +   +   AW  + DS    L L+++ + IAV V+YLA 
Sbjct: 160 PYQFLLKYAKQLKGDKN----KIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAG 215

Query: 205 QVYGVEVP--AEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIYT 246
           ++   E+         + WW+ F  D+   +++ I   ++ +Y+
Sbjct: 216 RLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYS 259


>gi|38176158 cyclin K isoform 2 [Homo sapiens]
          Length = 354

 Score = 91.7 bits (226), Expect = 6e-19
 Identities = 59/224 (26%), Positives = 106/224 (47%), Gaps = 10/224 (4%)

Query: 25  APAARVHFRVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLA 84
           A  AR     ARFI + G +LG+    +AT    + +F+       F  Y+     ++LA
Sbjct: 44  ATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLA 103

Query: 85  GKVEEQPLWAHDIISVSNRYFNPSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQH 144
           GKVEE P    DII  +    N        D    + ++ ++  E ++L+ ++F +  +H
Sbjct: 104 GKVEETPKKCKDIIKTARSLLNDVQFGQFGD----DPKEEVMVLERILLQTIKFDLQVEH 159

Query: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLAL 204
           P+++LL Y   LK   N    +   +   AW  + DS    L L+++ + IAV V+YLA 
Sbjct: 160 PYQFLLKYAKQLKGDKN----KIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAG 215

Query: 205 QVYGVEVP--AEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIYT 246
           ++   E+         + WW+ F  D+   +++ I   ++ +Y+
Sbjct: 216 RLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYS 259


>gi|88758580 cyclin L2 isoform A [Homo sapiens]
          Length = 520

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 60/212 (28%), Positives = 101/212 (47%), Gaps = 16/212 (7%)

Query: 38  IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDI 97
           I  AG+ L +  + +AT   ++ +FF            ++M+ ++LA K+EE P    D+
Sbjct: 85  IQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDV 144

Query: 98  ISVSNRYFNPSSE----PLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL 153
           I+V +R      +    PL LD     L++ I++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 145 INVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYL 204

Query: 154 VSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLALQVYGVEVPA 213
             L+   N H  Q      T+W  + DS    + +RFQ + IA   +YLA +   + +P 
Sbjct: 205 QVLECERNQHLVQ------TSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPN 258

Query: 214 EVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIY 245
                  W+  F    T+  I  I   ++Q+Y
Sbjct: 259 RPH----WFLLFG--ATEEEIQEICLKILQLY 284


>gi|9945320 cyclin L1 [Homo sapiens]
          Length = 526

 Score = 81.3 bits (199), Expect = 8e-16
 Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 16/213 (7%)

Query: 38  IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDI 97
           I  AG+ L +  + +AT   ++ +FF           ++AM+ I LA K+EE P    D+
Sbjct: 90  IQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDV 149

Query: 98  ISVSNRYFN----PSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL 153
           I+V +         +  PL LD      ++ +++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 150 INVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYL 209

Query: 154 VSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLALQVYGVEVPA 213
                 L C   +   +  TAW  + DS    + +RFQ + IA   +YLA +   + +P 
Sbjct: 210 ----QVLECE--RNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPT 263

Query: 214 EVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIYT 246
                  W+  F    T+  I  I  + +++YT
Sbjct: 264 RPH----WFLLFG--TTEEEIQEICIETLRLYT 290


>gi|17978469 cyclin T2 isoform b [Homo sapiens]
          Length = 730

 Score = 77.8 bits (190), Expect = 8e-15
 Identities = 57/218 (26%), Positives = 106/218 (48%), Gaps = 19/218 (8%)

Query: 33  RVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL 92
           + A  I E G +L +  + I TA     +F+       F+  +I+ ++++LA KVEEQ  
Sbjct: 39  QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98

Query: 93  WAHDIISVSNRYFNPSSEPLGLDSR---LWELRDSIVQRELLMLRVLRFQVSFQHPHKYL 149
               +I V++   +P  EPL LD++     +    +V  E +ML+ L F+++ +HPH   
Sbjct: 99  KLEHVIKVAHACLHP-LEPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH--- 153

Query: 150 LYYLVSLKNWLNCHSWQRT--PVAVTAWALLRDSYH-GGLCLRFQAQHIAVVVLYLALQV 206
                   + + C    R    +A T++ +  +S H    CL+++   IA V ++LA + 
Sbjct: 154 -------TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKW 206

Query: 207 YGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQI 244
              E+P   +  K WW+     +T  ++D +  + +QI
Sbjct: 207 SNWEIPVSTDG-KHWWEYVDPTVTLELLDELTHEFLQI 243


>gi|4502629 cyclin T2 isoform a [Homo sapiens]
          Length = 663

 Score = 77.8 bits (190), Expect = 8e-15
 Identities = 57/218 (26%), Positives = 106/218 (48%), Gaps = 19/218 (8%)

Query: 33  RVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL 92
           + A  I E G +L +  + I TA     +F+       F+  +I+ ++++LA KVEEQ  
Sbjct: 39  QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98

Query: 93  WAHDIISVSNRYFNPSSEPLGLDSR---LWELRDSIVQRELLMLRVLRFQVSFQHPHKYL 149
               +I V++   +P  EPL LD++     +    +V  E +ML+ L F+++ +HPH   
Sbjct: 99  KLEHVIKVAHACLHP-LEPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH--- 153

Query: 150 LYYLVSLKNWLNCHSWQRT--PVAVTAWALLRDSYH-GGLCLRFQAQHIAVVVLYLALQV 206
                   + + C    R    +A T++ +  +S H    CL+++   IA V ++LA + 
Sbjct: 154 -------TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKW 206

Query: 207 YGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQI 244
              E+P   +  K WW+     +T  ++D +  + +QI
Sbjct: 207 SNWEIPVSTDG-KHWWEYVDPTVTLELLDELTHEFLQI 243


>gi|17978466 cyclin T1 [Homo sapiens]
          Length = 726

 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 50/217 (23%), Positives = 103/217 (47%), Gaps = 17/217 (7%)

Query: 33  RVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL 92
           + A  + + G +L +  + I TA     +F+       F    +A ++++LA KVEEQP 
Sbjct: 40  QAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPK 99

Query: 93  WAHDIISVSNRYFNP--SSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLL 150
               +I V++   +P  S      ++ L +++D ++  E ++L+ L F+++  HPH ++ 
Sbjct: 100 KLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVI-LESIILQTLGFELTIDHPHTHV- 157

Query: 151 YYLVSLKNWLNCHSWQRT--PVAVTAWALLRDSYH-GGLCLRFQAQHIAVVVLYLALQVY 207
                    + C    R    +A T++ +  +S H     L++    +A V ++LA +  
Sbjct: 158 ---------VKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWS 208

Query: 208 GVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQI 244
             E+P   +  K WW+     +T  ++D +  + +QI
Sbjct: 209 NWEIPVSTDG-KHWWEYVDATVTLELLDELTHEFLQI 244


>gi|221554516 cyclin L2 isoform C [Homo sapiens]
          Length = 236

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 45/149 (30%), Positives = 74/149 (49%), Gaps = 4/149 (2%)

Query: 38  IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDI 97
           I  AG+ L +  + +AT   ++ +FF            ++M+ ++LA K+EE P    D+
Sbjct: 85  IQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDV 144

Query: 98  ISVSNRYFNPSSE----PLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL 153
           I+V +R      +    PL LD     L++ I++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 145 INVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYL 204

Query: 154 VSLKNWLNCHSWQRTPVAVTAWALLRDSY 182
             L+   N H  Q + VA     L  DS+
Sbjct: 205 QVLECERNQHLVQTSWVASEDPLLKWDSW 233


>gi|221554518 cyclin L2 isoform D [Homo sapiens]
          Length = 227

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 4/138 (2%)

Query: 38  IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDI 97
           I  AG+ L +  + +AT   ++ +FF            ++M+ ++LA K+EE P    D+
Sbjct: 85  IQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDV 144

Query: 98  ISVSNRYFNPSSE----PLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL 153
           I+V +R      +    PL LD     L++ I++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 145 INVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYL 204

Query: 154 VSLKNWLNCHSWQRTPVA 171
             L+   N H  Q + VA
Sbjct: 205 QVLECERNQHLVQTSWVA 222


>gi|88758578 cyclin L2 isoform B [Homo sapiens]
          Length = 226

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 4/138 (2%)

Query: 38  IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDI 97
           I  AG+ L +  + +AT   ++ +FF            ++M+ ++LA K+EE P    D+
Sbjct: 85  IQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDV 144

Query: 98  ISVSNRYFNPSSE----PLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL 153
           I+V +R      +    PL LD     L++ I++ E  +L+ L F V  +HPHK ++ YL
Sbjct: 145 INVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYL 204

Query: 154 VSLKNWLNCHSWQRTPVA 171
             L+   N H  Q + VA
Sbjct: 205 QVLECERNQHLVQTSWVA 222


>gi|61676091 cyclin C isoform a [Homo sapiens]
          Length = 283

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 33/216 (15%)

Query: 38  IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL----- 92
           I   G  L ++   IATA   + +F+    L + DP L+A + ++LA KVEE  +     
Sbjct: 48  IQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTR 107

Query: 93  ---WAHDIISVSNRYFNPSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYL 149
               A  ++     Y  P   P  +        + I++ E  +L ++   +   HP++ L
Sbjct: 108 LIAAATSVLKTRFSYAFPKEFPYRM--------NHILECEFYLLELMDCCLIVYHPYRPL 159

Query: 150 LYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLALQVYGV 209
           L Y+  +         Q   +   AW ++ D+Y   LCL +    IA+  L++A  V   
Sbjct: 160 LQYVQDM--------GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVV--- 208

Query: 210 EVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIY 245
               + +  + W+   S D+ K  I  I+  ++++Y
Sbjct: 209 ----QQKDARQWFAELSVDMEK--ILEIIRVILKLY 238


>gi|4502623 cyclin H [Homo sapiens]
          Length = 323

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 31/116 (26%), Positives = 57/116 (49%), Gaps = 14/116 (12%)

Query: 44  KLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDIISVSNR 103
           K  M    + TAC  + +F+    +  + P +I ++  +LA KV+E         +VS+ 
Sbjct: 72  KPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDE--------FNVSSP 123

Query: 104 YF--NPSSEPLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYLVSLK 157
            F  N    PLG +  L    + I++ ELL+++ L F +   +P++    +L+ LK
Sbjct: 124 QFVGNLRESPLGQEKAL----EQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLK 175


>gi|61676093 cyclin C isoform b [Homo sapiens]
          Length = 198

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 33/178 (18%)

Query: 76  IAMSSIYLAGKVEEQPLWAH--------DIISVSNRYFNPSSEPLGLDSRLWELRDSIVQ 127
           +A + ++LA KVEE  + ++         ++     Y  P   P  ++         I++
Sbjct: 1   MAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNH--------ILE 52

Query: 128 RELLMLRVLRFQVSFQHPHKYLLYYLVSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLC 187
            E  +L ++   +   HP++ LL Y+  +         Q   +   AW ++ D+Y   LC
Sbjct: 53  CEFYLLELMDCCLIVYHPYRPLLQYVQDMG--------QEDMLLPLAWRIVNDTYRTDLC 104

Query: 188 LRFQAQHIAVVVLYLALQVYGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIY 245
           L +    IA+  L++A  V       + +  + W+   S D+ K  I  I+  ++++Y
Sbjct: 105 LLYPPFMIALACLHVACVV-------QQKDARQWFAELSVDMEK--ILEIIRVILKLY 153


>gi|38373682 pleckstrin homology domain containing family G member 5
           isoform a [Homo sapiens]
          Length = 1006

 Score = 31.2 bits (69), Expect = 0.90
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAW--ALLRDSYHGGLCLRFQAQHIAVVVLYL 202
           PH+ L  Y + LK+ L      R   AV A   ++ R  +H   C+R + +   +  +  
Sbjct: 484 PHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVS 543

Query: 203 ALQVYGVEVPAEVEAEKLWWQAFSDDLTKPI 233
            +  Y V   +  E +KL  +    DLT PI
Sbjct: 544 RIDAYEVVESSSDEVDKLLKEFLHLDLTAPI 574


>gi|111154084 pleckstrin homology domain containing family G member
           5 isoform b [Homo sapiens]
          Length = 1083

 Score = 31.2 bits (69), Expect = 0.90
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAW--ALLRDSYHGGLCLRFQAQHIAVVVLYL 202
           PH+ L  Y + LK+ L      R   AV A   ++ R  +H   C+R + +   +  +  
Sbjct: 561 PHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVS 620

Query: 203 ALQVYGVEVPAEVEAEKLWWQAFSDDLTKPI 233
            +  Y V   +  E +KL  +    DLT PI
Sbjct: 621 RIDAYEVVESSSDEVDKLLKEFLHLDLTAPI 651


>gi|111154088 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 31.2 bits (69), Expect = 0.90
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAW--ALLRDSYHGGLCLRFQAQHIAVVVLYL 202
           PH+ L  Y + LK+ L      R   AV A   ++ R  +H   C+R + +   +  +  
Sbjct: 484 PHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVS 543

Query: 203 ALQVYGVEVPAEVEAEKLWWQAFSDDLTKPI 233
            +  Y V   +  E +KL  +    DLT PI
Sbjct: 544 RIDAYEVVESSSDEVDKLLKEFLHLDLTAPI 574


>gi|111154080 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 31.2 bits (69), Expect = 0.90
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAW--ALLRDSYHGGLCLRFQAQHIAVVVLYL 202
           PH+ L  Y + LK+ L      R   AV A   ++ R  +H   C+R + +   +  +  
Sbjct: 484 PHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVS 543

Query: 203 ALQVYGVEVPAEVEAEKLWWQAFSDDLTKPI 233
            +  Y V   +  E +KL  +    DLT PI
Sbjct: 544 RIDAYEVVESSSDEVDKLLKEFLHLDLTAPI 574


>gi|111154078 pleckstrin homology domain containing family G member
           5 isoform c [Homo sapiens]
          Length = 1062

 Score = 31.2 bits (69), Expect = 0.90
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 145 PHKYLLYYLVSLKNWLNCHSWQRTPVAVTAW--ALLRDSYHGGLCLRFQAQHIAVVVLYL 202
           PH+ L  Y + LK+ L      R   AV A   ++ R  +H   C+R + +   +  +  
Sbjct: 540 PHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVS 599

Query: 203 ALQVYGVEVPAEVEAEKLWWQAFSDDLTKPI 233
            +  Y V   +  E +KL  +    DLT PI
Sbjct: 600 RIDAYEVVESSSDEVDKLLKEFLHLDLTAPI 630


>gi|41352697 centromere protein I [Homo sapiens]
          Length = 756

 Score = 29.6 bits (65), Expect = 2.6
 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 9/83 (10%)

Query: 32  FRVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQP 91
           FRV R +++   K+GMQ  P   A     KFF   ++    P       IY       + 
Sbjct: 217 FRV-RKLLDLQAKMGMQ--PHLQALLSLYKFFAPALISVSLP---VRKKIYFKNS---EN 267

Query: 92  LWAHDIISVSNRYFNPSSEPLGL 114
           LW   +++V  R   PS EPL L
Sbjct: 268 LWKTALLAVKQRNRGPSPEPLKL 290


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 28.5 bits (62), Expect = 5.8
 Identities = 12/21 (57%), Positives = 14/21 (66%)

Query: 2    EGMEDAGEEAGEDAGEDAREG 22
            EG E+ GEE GE+ GE   EG
Sbjct: 989  EGEEEEGEEEGEEEGEGEEEG 1009


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score = 28.1 bits (61), Expect = 7.6
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 122 RDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL---VSLKNWLNCHSWQRT 168
           +  ++  ELL+L    + +    P  +L YYL   VS K+  +CH+W  T
Sbjct: 172 KKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDH-HCHTWPTT 220


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,194,109
Number of Sequences: 37866
Number of extensions: 368510
Number of successful extensions: 1022
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 962
Number of HSP's gapped (non-prelim): 33
length of query: 252
length of database: 18,247,518
effective HSP length: 100
effective length of query: 152
effective length of database: 14,460,918
effective search space: 2198059536
effective search space used: 2198059536
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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