Guide to the Human Genome
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Search of human proteins with 157389001

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157389001 tumor necrosis factor, alpha-induced protein
8-like 2 [Homo sapiens]
         (184 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157389001 tumor necrosis factor, alpha-induced protein 8-like...   362   e-100
gi|59709436 tumor necrosis factor, alpha-induced protein 8-like ...   209   8e-55
gi|117676370 tumor necrosis factor, alpha-induced protein 8 isof...   208   2e-54
gi|117676365 tumor necrosis factor, alpha-induced protein 8 isof...   208   2e-54
gi|22748781 tumor necrosis factor, alpha-induced protein 8-like ...   206   1e-53
gi|239508712 PREDICTED: similar to rCG47812 [Homo sapiens]             30   1.2  
gi|212286181 parvin, gamma [Homo sapiens]                              28   4.5  
gi|212286179 parvin, gamma [Homo sapiens]                              28   4.5  
gi|11545879 parvin, gamma [Homo sapiens]                               28   4.5  
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]               27   7.6  

>gi|157389001 tumor necrosis factor, alpha-induced protein 8-like 2
           [Homo sapiens]
          Length = 184

 Score =  362 bits (928), Expect = e-100
 Identities = 184/184 (100%), Positives = 184/184 (100%)

Query: 1   MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVI 60
           MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVI
Sbjct: 1   MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVI 60

Query: 61  KDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLL 120
           KDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLL
Sbjct: 61  KDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLL 120

Query: 121 TECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLD 180
           TECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLD
Sbjct: 121 TECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLD 180

Query: 181 EGKL 184
           EGKL
Sbjct: 181 EGKL 184


>gi|59709436 tumor necrosis factor, alpha-induced protein 8-like 3
           [Homo sapiens]
          Length = 292

 Score =  209 bits (533), Expect = 8e-55
 Identities = 100/180 (55%), Positives = 142/180 (78%), Gaps = 2/180 (1%)

Query: 4   FSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDL 63
           FSSKSLALQA+KK+LSK+A ++VA++ ID+TSSE+ DELY+V+KE+TH++ +A +++KDL
Sbjct: 110 FSSKSLALQAQKKILSKIASKTVANMLIDDTSSEIFDELYKVTKEHTHNKKEAHKIMKDL 169

Query: 64  IKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTEC 123
           IKVAIK+ +L+RN  F   EL +  +FR+KL Q AMT +SF EV++TF+  VL+ LL EC
Sbjct: 170 IKVAIKIGILYRNNQFSQEELVIVEKFRKKLNQTAMTIVSFYEVEYTFDRNVLSNLLHEC 229

Query: 124 RDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYG--PDFTQHLGKICDGLRKLLDE 181
           +D++ ELV+ HLTP++HGRI HVF+HF+D   L+ LY    D   +L +IC+G+ KLLDE
Sbjct: 230 KDLVHELVQRHLTPRTHGRINHVFNHFADVEFLSTLYSLDGDCRPNLKRICEGINKLLDE 289


>gi|117676370 tumor necrosis factor, alpha-induced protein 8 isoform
           b [Homo sapiens]
          Length = 188

 Score =  208 bits (530), Expect = 2e-54
 Identities = 99/180 (55%), Positives = 140/180 (77%), Gaps = 2/180 (1%)

Query: 4   FSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDL 63
           F+SK+LA+QA+KK+L KM  +S+A   ID+TSSEVLDELYRV++EYT ++ +A+++IK+L
Sbjct: 6   FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNL 65

Query: 64  IKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTEC 123
           IK  IK+A+L+RN  F   ELAL  +F++K+ Q AMT +SF +VD+TF+  VL+ LL EC
Sbjct: 66  IKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNEC 125

Query: 124 RDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGP--DFTQHLGKICDGLRKLLDE 181
           R++L ++++ HLT KSHGR+ +VFDHFSD   L ALY P  +F  HL K+CDG+ K+LDE
Sbjct: 126 REMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDE 185


>gi|117676365 tumor necrosis factor, alpha-induced protein 8 isoform
           a [Homo sapiens]
          Length = 198

 Score =  208 bits (530), Expect = 2e-54
 Identities = 99/180 (55%), Positives = 140/180 (77%), Gaps = 2/180 (1%)

Query: 4   FSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDL 63
           F+SK+LA+QA+KK+L KM  +S+A   ID+TSSEVLDELYRV++EYT ++ +A+++IK+L
Sbjct: 16  FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNL 75

Query: 64  IKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTEC 123
           IK  IK+A+L+RN  F   ELAL  +F++K+ Q AMT +SF +VD+TF+  VL+ LL EC
Sbjct: 76  IKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNEC 135

Query: 124 RDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGP--DFTQHLGKICDGLRKLLDE 181
           R++L ++++ HLT KSHGR+ +VFDHFSD   L ALY P  +F  HL K+CDG+ K+LDE
Sbjct: 136 REMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDE 195


>gi|22748781 tumor necrosis factor, alpha-induced protein 8-like 1
           [Homo sapiens]
          Length = 186

 Score =  206 bits (523), Expect = 1e-53
 Identities = 106/186 (56%), Positives = 139/186 (74%), Gaps = 2/186 (1%)

Query: 1   MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVI 60
           M++FS+KSLALQA+KKLLSKMA ++V  + +D+TSSEVLDELYR ++E+T SR +AQ+++
Sbjct: 1   MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML 60

Query: 61  KDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLL 120
           K+L+KVA+K+ +L R    G  ELAL  RFR + R  AMTA+SF +VDFTF+  VLA  L
Sbjct: 61  KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGL 120

Query: 121 TECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGP--DFTQHLGKICDGLRKL 178
            ECRD+L + V  HLT KSHGRI HVF H +D   L ALYGP   +  HL +IC+GL ++
Sbjct: 121 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM 180

Query: 179 LDEGKL 184
           LDEG L
Sbjct: 181 LDEGSL 186


>gi|239508712 PREDICTED: similar to rCG47812 [Homo sapiens]
          Length = 812

 Score = 30.0 bits (66), Expect = 1.2
 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query: 128 LELVEHHLTPK-SHGRIRHVFDHFSDPGLLTALYGPD 163
           LELVEH L      GR+R V  H   PGL   ++GP+
Sbjct: 579 LELVEHELAQACQQGRLRVVPSHDVAPGLGIQVFGPE 615


>gi|212286181 parvin, gamma [Homo sapiens]
          Length = 331

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 33/136 (24%), Positives = 52/136 (38%), Gaps = 35/136 (25%)

Query: 32  DETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFR 91
           DE   +V DEL++++ E  ++           +K AI   V  +    G S   L T+F 
Sbjct: 191 DEPPKDVFDELFKLAPEKVNA-----------VKEAIVNFVNQKLDRLGLSVQNLDTQFA 239

Query: 92  QKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRH----VF 147
                G +  L  G+++  F                L L E +LTP S   + H      
Sbjct: 240 D----GVILLLLIGQLEGFF----------------LHLKEFYLTPNSPAEMLHNVTLAL 279

Query: 148 DHFSDPGLLTALYGPD 163
           +   D GLL+    P+
Sbjct: 280 ELLKDEGLLSCPVSPE 295


>gi|212286179 parvin, gamma [Homo sapiens]
          Length = 331

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 33/136 (24%), Positives = 52/136 (38%), Gaps = 35/136 (25%)

Query: 32  DETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFR 91
           DE   +V DEL++++ E  ++           +K AI   V  +    G S   L T+F 
Sbjct: 191 DEPPKDVFDELFKLAPEKVNA-----------VKEAIVNFVNQKLDRLGLSVQNLDTQFA 239

Query: 92  QKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRH----VF 147
                G +  L  G+++  F                L L E +LTP S   + H      
Sbjct: 240 D----GVILLLLIGQLEGFF----------------LHLKEFYLTPNSPAEMLHNVTLAL 279

Query: 148 DHFSDPGLLTALYGPD 163
           +   D GLL+    P+
Sbjct: 280 ELLKDEGLLSCPVSPE 295


>gi|11545879 parvin, gamma [Homo sapiens]
          Length = 331

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 33/136 (24%), Positives = 52/136 (38%), Gaps = 35/136 (25%)

Query: 32  DETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFR 91
           DE   +V DEL++++ E  ++           +K AI   V  +    G S   L T+F 
Sbjct: 191 DEPPKDVFDELFKLAPEKVNA-----------VKEAIVNFVNQKLDRLGLSVQNLDTQFA 239

Query: 92  QKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRH----VF 147
                G +  L  G+++  F                L L E +LTP S   + H      
Sbjct: 240 D----GVILLLLIGQLEGFF----------------LHLKEFYLTPNSPAEMLHNVTLAL 279

Query: 148 DHFSDPGLLTALYGPD 163
           +   D GLL+    P+
Sbjct: 280 ELLKDEGLLSCPVSPE 295


>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
          Length = 1012

 Score = 27.3 bits (59), Expect = 7.6
 Identities = 16/75 (21%), Positives = 38/75 (50%)

Query: 1   MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVI 60
           +ES  ++SLA+  +  +L++       +  + E   E+L +   + ++   SR +  R++
Sbjct: 410 LESVKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLL 469

Query: 61  KDLIKVAIKVAVLHR 75
             L + A ++AV  +
Sbjct: 470 NRLAQPAPELAVFQK 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,410,392
Number of Sequences: 37866
Number of extensions: 245573
Number of successful extensions: 579
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 569
Number of HSP's gapped (non-prelim): 10
length of query: 184
length of database: 18,247,518
effective HSP length: 96
effective length of query: 88
effective length of database: 14,612,382
effective search space: 1285889616
effective search space used: 1285889616
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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