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Search of human proteins with 157388991
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157388991 solute carrier family 25, member 36 isoform b
[Homo sapiens]
(310 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 612 e-175
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 607 e-174
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 366 e-101
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 124 1e-28
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 111 9e-25
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 105 4e-23
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 105 7e-23
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 105 7e-23
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 105 7e-23
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 105 7e-23
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 105 7e-23
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 105 7e-23
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 104 9e-23
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 104 9e-23
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 102 3e-22
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 102 3e-22
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 100 2e-21
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 97 2e-20
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 94 1e-19
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 92 4e-19
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 87 1e-17
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 86 3e-17
gi|116235466 solute carrier family 25, member 45 isoform b [Homo... 86 4e-17
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 86 4e-17
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 81 1e-15
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 80 2e-15
gi|5453918 solute carrier family 25 (mitochondrial carrier; pero... 80 2e-15
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 79 4e-15
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 79 5e-15
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 78 9e-15
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 612 bits (1578), Expect = e-175
Identities = 310/310 (100%), Positives = 310/310 (100%)
Query: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV
Sbjct: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
Query: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV 120
SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV
Sbjct: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV 120
Query: 121 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM 180
HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM
Sbjct: 121 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM 180
Query: 181 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA
Sbjct: 181 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
Query: 241 TTIAYPHVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMAT 300
TTIAYPHVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMAT
Sbjct: 241 TTIAYPHVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMAT 300
Query: 301 YELVVYLLNG 310
YELVVYLLNG
Sbjct: 301 YELVVYLLNG 310
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 607 bits (1566), Expect = e-174
Identities = 310/311 (99%), Positives = 310/311 (99%), Gaps = 1/311 (0%)
Query: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV
Sbjct: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
Query: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV 120
SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV
Sbjct: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV 120
Query: 121 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM 180
HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM
Sbjct: 121 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM 180
Query: 181 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA
Sbjct: 181 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
Query: 241 TTIAYPH-VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
TTIAYPH VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA
Sbjct: 241 TTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 300
Query: 300 TYELVVYLLNG 310
TYELVVYLLNG
Sbjct: 301 TYELVVYLLNG 311
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 366 bits (940), Expect = e-101
Identities = 187/312 (59%), Positives = 236/312 (75%), Gaps = 9/312 (2%)
Query: 3 QRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSV---TLYISEVQLNTMAGASVNRV 59
+ +TL+HLFAGGCGGTVGAI TCPLEV+KTRLQSS + T+Y +V L T++GA + R
Sbjct: 8 KENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRP 67
Query: 60 --VSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS 117
V+PG LK ILEKEGP+SLFRGLGPNLVGVAPSRA+YFA YS KE+ N +F P+S
Sbjct: 68 TSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNS 127
Query: 118 TQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFY 177
VH+ SA A F + NPIW++KTR+QL+ + RG ++M +C R VYQT+G++GFY
Sbjct: 128 NIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFY 187
Query: 178 RGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSK 237
RG++ASYAGISET+I F IYES+K+ L E AS+ E K ++ F G+M AAA SK
Sbjct: 188 RGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTE---KNSTSFFGLMAAAALSK 244
Query: 238 TCATTIAYPH-VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAI 296
CA+ IAYPH V+RTRLREEGTKY+SF QT L+ +EEGY + YRGL L+RQIPNTAI
Sbjct: 245 GCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAI 304
Query: 297 MMATYELVVYLL 308
+++TYEL+VYLL
Sbjct: 305 VLSTYELIVYLL 316
Score = 36.2 bits (82), Expect = 0.038
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 235 TSKTCATTIAYPHVVRTRLREEG-----TKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVR 289
+S+ T+ YP V + G + FQ L ++++EG SL+RGL +LV
Sbjct: 41 SSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVG 100
Query: 290 QIPNTAIMMATYELVVYLLNG 310
P+ A+ A Y NG
Sbjct: 101 VAPSRAVYFACYSKAKEQFNG 121
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 124 bits (311), Expect = 1e-28
Identities = 91/306 (29%), Positives = 144/306 (47%), Gaps = 29/306 (9%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
+L AG GG + + PL++VK R S G + R G LHCL
Sbjct: 25 NLIAGVSGGVLSNLALHPLDLVKIRFAVSD--------------GLEL-RPKYNGILHCL 69
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKE-KLNDVFDPDSTQVHMISAAM 127
I + +G R L++G+ PN+ G S +YF Y+ K K + +++SAA
Sbjct: 70 TTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAE 129
Query: 128 AGFTAITATNPIWLIKTRLQL--DARNRGERRM--GAFECVRKVYQTDGLKGFYRGMSAS 183
AG + TNP+W+ KTRL L DA R G F+ + K+Y+ +G++G Y+G
Sbjct: 130 AGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPG 189
Query: 184 YAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTI 243
G S + F+ YE +K K ++ + E+ +++ + AA SK A
Sbjct: 190 LFGTSHGALQFMAYELLKLKYNQH-----INRLPEAQLSTVEYISV---AALSKIFAVAA 241
Query: 244 AYPH-VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
YP+ VVR RL+++ Y ++ ++EG G Y+G+ +L+R P I YE
Sbjct: 242 TYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYE 301
Query: 303 LVVYLL 308
V + L
Sbjct: 302 NVSHFL 307
Score = 35.8 bits (81), Expect = 0.050
Identities = 25/111 (22%), Positives = 40/111 (36%), Gaps = 20/111 (18%)
Query: 2 SQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVS 61
+Q T+ ++ T P +VV+ RLQ +
Sbjct: 220 AQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQ--------------------HMFY 259
Query: 62 PGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDV 112
G + + KEG ++G+ PNL+ V P+ I F Y N L D+
Sbjct: 260 SGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLDL 310
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 111 bits (277), Expect = 9e-25
Identities = 85/305 (27%), Positives = 137/305 (44%), Gaps = 30/305 (9%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
H+ AG G + + P++ VKTR+QS S + Q ++ GA L
Sbjct: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPD---PKAQYTSIYGA-------------L 91
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVF--DPDSTQVHMISAA 126
K I+ EG RG+ ++G P+ A+YFA Y N K LNDVF +S + I+ +
Sbjct: 92 KKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGS 151
Query: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYA- 185
MA NP ++K RLQ+ + A C+R V++T+GL FYR +
Sbjct: 152 MATLLHDAVMNPAEVVKQRLQM----YNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTM 207
Query: 186 GISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATS--KTCATTI 243
I IHF+ YE +++++ ++T + +S + G + AAAT+ C T +
Sbjct: 208 NIPFQSIHFITYEFLQEQVNPHRT-----YNPQSHIISGGLAGALAAAATTPLDVCKTLL 262
Query: 244 AYPHVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYEL 303
V L + + Q G ++G+ ++ Q+P+TAI + YE
Sbjct: 263 NTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEF 322
Query: 304 VVYLL 308
Y L
Sbjct: 323 FKYFL 327
Score = 62.8 bits (151), Expect = 4e-10
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 13/195 (6%)
Query: 117 STQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGF 176
S HM + AMAG + P+ +KTR+Q + + + + ++K+ +T+G
Sbjct: 44 SVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRP 103
Query: 177 YRGMSASYAGISET-VIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT 235
RG++ G ++F YE++K+ L ++ + + + +A +
Sbjct: 104 LRGVNVMIMGAGPAHAMYFACYENMKRTL-----------NDVFHHQGNSHLANGIAGSM 152
Query: 236 SKTCATTIAYP-HVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNT 294
+ + P VV+ RL+ +++RS + + + EG G+ YR TT L IP
Sbjct: 153 ATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQ 212
Query: 295 AIMMATYELVVYLLN 309
+I TYE + +N
Sbjct: 213 SIHFITYEFLQEQVN 227
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 105 bits (263), Expect = 4e-23
Identities = 89/301 (29%), Positives = 143/301 (47%), Gaps = 40/301 (13%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEV-QLNTMAGASVNRVVSPGPLHCL 68
L AG G V T PL+ +K +Q ++ S+ +LN + G L
Sbjct: 189 LVAGAVAGAVSRTGTAPLDRLKVFMQ-----VHASKTNRLNILGG--------------L 229
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMA 128
+ ++ + G RSL+RG G N++ +AP AI F AY K + + Q ++ ++A
Sbjct: 230 RSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLA 289
Query: 129 GFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGIS 188
G TA T P+ ++KTRL L R G+ + G +C R++ + +G + FYRG + GI
Sbjct: 290 GATAQTIIYPMEVLKTRLTL--RRTGQYK-GLLDCARRILEREGPRAFYRGYLPNVLGII 346
Query: 189 ETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIAYP 246
I +YE++K L+ + S A + ++LA T S TC +YP
Sbjct: 347 PYAGIDLAVYETLKNWWLQ----------QYSHDSADPGILVLLACGTISSTCGQIASYP 396
Query: 247 -HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 301
+VRTR++ EG S L ++ +EG LYRG+ + ++ IP +I Y
Sbjct: 397 LALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVY 456
Query: 302 E 302
E
Sbjct: 457 E 457
Score = 52.4 bits (124), Expect = 5e-07
Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 16/103 (15%)
Query: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLH 66
LV L G T G I + PL +V+TR+Q A AS+ L
Sbjct: 377 LVLLACGTISSTCGQIASYPLALVRTRMQ----------------AQASIEGGPQLSMLG 420
Query: 67 CLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL 109
L+ IL +EG R L+RG+ PN + V P+ +I + Y N K+ L
Sbjct: 421 LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 105 bits (261), Expect = 7e-23
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 230
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 288
Query: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 289 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 345
Query: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 346 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 395
Query: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
Query: 300 TYE 302
YE
Sbjct: 456 VYE 458
Score = 46.2 bits (108), Expect = 4e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 379 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 422
Query: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 105 bits (261), Expect = 7e-23
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 264
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 265 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 322
Query: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 323 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 379
Query: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 380 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 429
Query: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 430 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
Query: 300 TYE 302
YE
Sbjct: 490 VYE 492
Score = 46.2 bits (108), Expect = 4e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 413 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 456
Query: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 457 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 105 bits (261), Expect = 7e-23
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 209 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 250
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 251 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 308
Query: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 309 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 365
Query: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 366 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 415
Query: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 416 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 475
Query: 300 TYE 302
YE
Sbjct: 476 VYE 478
Score = 46.2 bits (108), Expect = 4e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 399 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 442
Query: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 443 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 105 bits (261), Expect = 7e-23
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 230
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 288
Query: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 289 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 345
Query: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 346 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 395
Query: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
Query: 300 TYE 302
YE
Sbjct: 456 VYE 458
Score = 46.2 bits (108), Expect = 4e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 379 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 422
Query: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 105 bits (261), Expect = 7e-23
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 86 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 127
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 128 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 185
Query: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 186 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 242
Query: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 243 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 292
Query: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 293 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 352
Query: 300 TYE 302
YE
Sbjct: 353 VYE 355
Score = 46.2 bits (108), Expect = 4e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 276 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 319
Query: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 320 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 105 bits (261), Expect = 7e-23
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 264
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 265 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 322
Query: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 323 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 379
Query: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 380 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 429
Query: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 430 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
Query: 300 TYE 302
YE
Sbjct: 490 VYE 492
Score = 46.2 bits (108), Expect = 4e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 413 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 456
Query: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 457 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 104 bits (260), Expect = 9e-23
Identities = 82/299 (27%), Positives = 135/299 (45%), Gaps = 36/299 (12%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
L AGG G V T PL+ +K +Q ++N G +
Sbjct: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS----KSDKMNIFGG--------------FR 239
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
++++ G RSL+RG G N++ +AP A+ F AY K+ L + T IS +MAG
Sbjct: 240 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 299
Query: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189
TA T P+ ++KTRL A + + G ++C +K+ + +GL FY+G + GI
Sbjct: 300 ATAQTFIYPMEVMKTRL---AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIP 356
Query: 190 TV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-H 247
I +YE +K L+ ++ + ++ A S TC +YP
Sbjct: 357 YAGIDLAVYELLKSYWLDNFAKDSVN---------PGVMVLLGCGALSSTCGQLASYPLA 407
Query: 248 VVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
+VRTR++ EG+ + ++ +EG LYRG+T + ++ +P I YE
Sbjct: 408 LVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466
Score = 80.1 bits (196), Expect = 2e-15
Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 24/204 (11%)
Query: 6 TLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPL 65
T +G G P+EV+KTRL Y G
Sbjct: 288 TFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQY-------------------SGIY 328
Query: 66 HCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS----TQVH 121
C K IL+ EG + ++G PNL+G+ P I A Y K D F DS V
Sbjct: 329 DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVL 388
Query: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
+ A++ A+ P+ L++TR+Q A G ++ R++ +G+ G YRG++
Sbjct: 389 LGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGIT 448
Query: 182 ASYAGISETV-IHFVIYESIKQKL 204
++ + V I +V+YE++KQ L
Sbjct: 449 PNFMKVLPAVGISYVVYENMKQTL 472
Score = 63.2 bits (152), Expect = 3e-10
Identities = 49/186 (26%), Positives = 88/186 (47%), Gaps = 18/186 (9%)
Query: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
+++ +AG + T+T P+ +K +Q+ +M F R++ + G++ +RG
Sbjct: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSD--KMNIFGGFRQMVKEGGIRSLWRGNG 255
Query: 182 ASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
+ I+ ET + F YE K+ L E + + + F+ +A AT A
Sbjct: 256 TNVIKIAPETAVKFWAYEQYKKLLTE---------EGQKIGTFERFISGSMAGAT----A 302
Query: 241 TTIAYP-HVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMM 298
T YP V++TRL T +Y + +++ EG G+ Y+G +L+ IP I +
Sbjct: 303 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362
Query: 299 ATYELV 304
A YEL+
Sbjct: 363 AVYELL 368
Score = 30.8 bits (68), Expect = 1.6
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 218 ESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKY--RSFFQTLSLLVQEE 274
E K++ + +LA + + T P ++ ++ G+K + F +V+E
Sbjct: 186 EDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEG 245
Query: 275 GYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 308
G SL+RG T++++ P TA+ YE LL
Sbjct: 246 GIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLL 279
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 104 bits (260), Expect = 9e-23
Identities = 82/299 (27%), Positives = 135/299 (45%), Gaps = 36/299 (12%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
L AGG G V T PL+ +K +Q ++N G +
Sbjct: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS----KSDKMNIFGG--------------FR 220
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
++++ G RSL+RG G N++ +AP A+ F AY K+ L + T IS +MAG
Sbjct: 221 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 280
Query: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189
TA T P+ ++KTRL A + + G ++C +K+ + +GL FY+G + GI
Sbjct: 281 ATAQTFIYPMEVMKTRL---AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIP 337
Query: 190 TV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-H 247
I +YE +K L+ ++ + ++ A S TC +YP
Sbjct: 338 YAGIDLAVYELLKSYWLDNFAKDSVN---------PGVMVLLGCGALSSTCGQLASYPLA 388
Query: 248 VVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
+VRTR++ EG+ + ++ +EG LYRG+T + ++ +P I YE
Sbjct: 389 LVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
Score = 80.1 bits (196), Expect = 2e-15
Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 24/204 (11%)
Query: 6 TLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPL 65
T +G G P+EV+KTRL Y G
Sbjct: 269 TFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQY-------------------SGIY 309
Query: 66 HCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS----TQVH 121
C K IL+ EG + ++G PNL+G+ P I A Y K D F DS V
Sbjct: 310 DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVL 369
Query: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
+ A++ A+ P+ L++TR+Q A G ++ R++ +G+ G YRG++
Sbjct: 370 LGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGIT 429
Query: 182 ASYAGISETV-IHFVIYESIKQKL 204
++ + V I +V+YE++KQ L
Sbjct: 430 PNFMKVLPAVGISYVVYENMKQTL 453
Score = 63.2 bits (152), Expect = 3e-10
Identities = 49/186 (26%), Positives = 88/186 (47%), Gaps = 18/186 (9%)
Query: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
+++ +AG + T+T P+ +K +Q+ +M F R++ + G++ +RG
Sbjct: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSD--KMNIFGGFRQMVKEGGIRSLWRGNG 236
Query: 182 ASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
+ I+ ET + F YE K+ L E + + + F+ +A AT A
Sbjct: 237 TNVIKIAPETAVKFWAYEQYKKLLTE---------EGQKIGTFERFISGSMAGAT----A 283
Query: 241 TTIAYP-HVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMM 298
T YP V++TRL T +Y + +++ EG G+ Y+G +L+ IP I +
Sbjct: 284 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343
Query: 299 ATYELV 304
A YEL+
Sbjct: 344 AVYELL 349
Score = 30.8 bits (68), Expect = 1.6
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 218 ESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKY--RSFFQTLSLLVQEE 274
E K++ + +LA + + T P ++ ++ G+K + F +V+E
Sbjct: 167 EDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEG 226
Query: 275 GYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 308
G SL+RG T++++ P TA+ YE LL
Sbjct: 227 GIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLL 260
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 102 bits (255), Expect = 3e-22
Identities = 81/298 (27%), Positives = 132/298 (44%), Gaps = 35/298 (11%)
Query: 13 GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72
G G VGA P+++VKTR+Q+ T G+ V ++ C K +L
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRST------------GSFVGELMYKNSFDCFKKVL 382
Query: 73 EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132
EG L+RGL P L+GVAP +AI ++K +++ AG +
Sbjct: 383 RYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ 442
Query: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191
+ TNP+ ++K RLQ+ R+ A VR + G G Y+G A + I +
Sbjct: 443 VIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSA 498
Query: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVR 250
I+F Y +K ++ N++ V S ++LA A + A ++ P V++
Sbjct: 499 IYFPCYAHVK---------ASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIK 545
Query: 251 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 304
TRL R T Y +++EEG +L++G + R P + + TYEL+
Sbjct: 546 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
Score = 69.7 bits (169), Expect = 3e-12
Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 20/173 (11%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
+ AGGC G I T PLE+VK RLQ +AG ++ GP
Sbjct: 432 ILAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 471
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
++ G +++G + P AIYF Y++ K + S +++ A+AG
Sbjct: 472 SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAG 531
Query: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSA 182
A + P +IKTRLQ+ AR G +C RK+ + +G K ++G A
Sbjct: 532 MPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGA 584
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 102 bits (255), Expect = 3e-22
Identities = 81/298 (27%), Positives = 132/298 (44%), Gaps = 35/298 (11%)
Query: 13 GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72
G G VGA P+++VKTR+Q+ T G+ V ++ C K +L
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRST------------GSFVGELMYKNSFDCFKKVL 383
Query: 73 EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132
EG L+RGL P L+GVAP +AI ++K +++ AG +
Sbjct: 384 RYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQ 443
Query: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191
+ TNP+ ++K RLQ+ R+ A VR + G G Y+G A + I +
Sbjct: 444 VIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSA 499
Query: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVR 250
I+F Y +K ++ N++ V S ++LA A + A ++ P V++
Sbjct: 500 IYFPCYAHVK---------ASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIK 546
Query: 251 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 304
TRL R T Y +++EEG +L++G + R P + + TYEL+
Sbjct: 547 TRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604
Score = 69.7 bits (169), Expect = 3e-12
Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 20/173 (11%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
+ AGGC G I T PLE+VK RLQ +AG ++ GP
Sbjct: 433 ILAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 472
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
++ G +++G + P AIYF Y++ K + S +++ A+AG
Sbjct: 473 SVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAG 532
Query: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSA 182
A + P +IKTRLQ+ AR G +C RK+ + +G K ++G A
Sbjct: 533 MPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGA 585
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 100 bits (248), Expect = 2e-21
Identities = 86/309 (27%), Positives = 134/309 (43%), Gaps = 44/309 (14%)
Query: 11 FAGGC-GGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
F GC GG G ++ P + VK RLQ SV + G LHC K
Sbjct: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSV-----------------EKPQYRGTLHCFK 47
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
I+++E L++GLG L+G+ A+ F N L DS ++ A AG
Sbjct: 48 SIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGH----DSPLNQFLAGAAAG 103
Query: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189
P+ L KTRLQL G+ +C+ ++Y +GL+G RGM ++ + E
Sbjct: 104 AIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTL--LRE 161
Query: 190 TV---IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP 246
T ++F+ Y+++ + L D V + ++LA TS + YP
Sbjct: 162 TPSFGVYFLTYDALTRAL------GCEPGDRLLVPK------LLLAGGTSGIVSWLSTYP 209
Query: 247 -HVVRTRLREEG----TKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 301
VV++RL+ +G +YR + + EG+ RGL + L+R P A AT
Sbjct: 210 VDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATV 269
Query: 302 ELVVYLLNG 310
+V+ G
Sbjct: 270 TVVLTYARG 278
Score = 72.8 bits (177), Expect = 4e-13
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLH 66
L AG G + ++ CP+E+ KTRLQ + A R G L
Sbjct: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQ---------------LQDAGPARTYK-GSLD 136
Query: 67 CLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLN-DVFDPDSTQVHMISA 125
CL I EG R + RG+ L+ PS +YF Y L + D +++
Sbjct: 137 CLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAG 196
Query: 126 AMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSAS 183
+G + +T P+ ++K+RLQ D R G +CV + Y+ +G + F RG++++
Sbjct: 197 GTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLAST 254
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 96.7 bits (239), Expect = 2e-20
Identities = 77/298 (25%), Positives = 129/298 (43%), Gaps = 35/298 (11%)
Query: 13 GGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVIL 72
G G VGA P+++VKTR+Q+ + G+ V ++ C K +L
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGS------------GSVVGELMYKNSFDCFKKVL 380
Query: 73 EKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTA 132
EG L+RGL P L+GVAP +AI ++K +++ AG +
Sbjct: 381 RYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQ 440
Query: 133 ITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY-AGISETV 191
+ TNP+ ++K RLQ+ R+ A +R + G+ G Y+G A + I +
Sbjct: 441 VIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSA 496
Query: 192 IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVR 250
I+F +Y K L + EN + ++ A A + A ++ P V++
Sbjct: 497 IYFPVYAHCKLLLAD-------ENGHVG------GLNLLAAGAMAGVPAASLVTPADVIK 543
Query: 251 TRL----REEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 304
TRL R T Y +++EEG + ++G + R P + + TYEL+
Sbjct: 544 TRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELL 601
Score = 75.5 bits (184), Expect = 6e-14
Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 21/194 (10%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
+ AGGC G I T PLE+VK RLQ +AG ++ GP
Sbjct: 430 VLAGGCAGGSQVIFTNPLEIVKIRLQ---------------VAGE-----ITTGPRVSAL 469
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
+L G L++G + P AIYF Y++CK L D + + AMAG
Sbjct: 470 NVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAG 529
Query: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSAS-YAGIS 188
A + P +IKTRLQ+ AR G +C RK+ + +G F++G +A +
Sbjct: 530 VPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSP 589
Query: 189 ETVIHFVIYESIKQ 202
+ + V YE +++
Sbjct: 590 QFGVTLVTYELLQR 603
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 94.4 bits (233), Expect = 1e-19
Identities = 79/298 (26%), Positives = 134/298 (44%), Gaps = 36/298 (12%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
L +G G V T PL+ K +Q +Y S+ + G L+
Sbjct: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQ-----VYSSKTNFTNLLGG-------------LQ 137
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
++++ G RSL+RG G N++ +AP AI F+ + CK + Q +++ ++A
Sbjct: 138 SMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAV 197
Query: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG-IS 188
+ T NP+ ++KTRL L R G+ + G +C R++ Q +G + YRG + G I
Sbjct: 198 AISQTLINPMEVLKTRLTL--RRTGQYK-GLLDCARQILQREGTRALYRGYLPNMLGIIP 254
Query: 189 ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-H 247
+YE + + K+ M + V +S S TC +YP
Sbjct: 255 YACTDLAVYEML--QCFWVKSGRDMGDPSGLVSLSS--------VTLSTTCGQMASYPLT 304
Query: 248 VVRTRLREEGTKYRS---FFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
+VRTR++ + T S L ++ ++G+ LYRG+T L++ +P I YE
Sbjct: 305 LVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYE 362
Score = 49.3 bits (116), Expect = 4e-06
Identities = 44/187 (23%), Positives = 82/187 (43%), Gaps = 20/187 (10%)
Query: 122 MISAAMAGFTAITATNPIWLIKTRLQL-DARNRGERRMGAFECVRKVYQTDGLKGFYRGM 180
++S AMAG + T T P+ K +Q+ ++ +G + + Q G + +RG
Sbjct: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQ---SMVQEGGFRSLWRGN 152
Query: 181 SASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTC 239
+ I+ E I F ++E K ++ + F +LA + +
Sbjct: 153 GINVLKIAPEYAIKFSVFEQCKNYFC-------------GIQGSPPFQERLLAGSLAVAI 199
Query: 240 ATTIAYP-HVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIM 297
+ T+ P V++TRL T +Y+ ++Q EG +LYRG +++ IP
Sbjct: 200 SQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTD 259
Query: 298 MATYELV 304
+A YE++
Sbjct: 260 LAVYEML 266
Score = 37.7 bits (86), Expect = 0.013
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 17/109 (15%)
Query: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
M LV L + T G + + PL +V+TR+Q+ E TM G
Sbjct: 277 MGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV----EGSNPTMRGV------ 326
Query: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL 109
L+ IL ++G L+RG+ P L+ V P+ I + Y K+ L
Sbjct: 327 -------LQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 92.4 bits (228), Expect = 4e-19
Identities = 89/309 (28%), Positives = 133/309 (43%), Gaps = 39/309 (12%)
Query: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
H+ AG G + + P++ VKTR+QS L A V L L
Sbjct: 75 HMVAGAVAGILEHCVMYPIDCVKTRMQS-----------LQPDPAARYRNV-----LEAL 118
Query: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMA 128
I+ EG RGL G P+ A+YFA Y K+ L+DV P H+ + A A
Sbjct: 119 WRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNS-HIANGA-A 176
Query: 129 GFTAI----TATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASY 184
G A A NP ++K R+Q+ N R+ +CVR V+Q +G FYR +
Sbjct: 177 GCVATLLHDAAMNPAEVVKQRMQM--YNSPYHRV--TDCVRAVWQNEGAGAFYRSYTTQL 232
Query: 185 A-GISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATS--KTCAT 241
+ IHF+ YE ++ E+ N V + G + AAAT+ C T
Sbjct: 233 TMNVPFQAIHFMTYEFLQ----EHFNPQRRYNPSSHVLSGA-CAGAVAAAATTPLDVCKT 287
Query: 242 TIAYPH--VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
+ + + + T S F+T + Q G + +RG+ ++ QIP+TAI +
Sbjct: 288 LLNTQESLALNSHITGHITGMASAFRT---VYQVGGVTAYFRGVQARVIYQIPSTAIAWS 344
Query: 300 TYELVVYLL 308
YE YL+
Sbjct: 345 VYEFFKYLI 353
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 87.4 bits (215), Expect = 1e-17
Identities = 79/309 (25%), Positives = 129/309 (41%), Gaps = 41/309 (13%)
Query: 12 AGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVI 71
AGG G PL+ VK LQ+ + + G L+ +
Sbjct: 42 AGGIAGCCAKTTVAPLDRVKVLLQAHN------------------HHYKHLGVFSALRAV 83
Query: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFT 131
+KEG L++G G ++ + P AI F A+ + K + +++ +MAG T
Sbjct: 84 PQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMT 143
Query: 132 AITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTD-GLKGFYRGM------SASY 184
A+ T P+ +++ RL + G + +Y + G GFYRG+ A Y
Sbjct: 144 AVICTYPLDMVRVRLAFQVKGE-HSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPY 202
Query: 185 AGISETVIHFVIYESIKQKLLEYKTA--STMENDEESVKEASDFVGMMLAAATSKTCATT 242
AG+S F + ++K L + +D +V V +L + A T
Sbjct: 203 AGVS-----FFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVN-LLCGGVAGAIAQT 256
Query: 243 IAYPHVVRTRLREEGTKYRSFFQTLSLL-VQEEGYG------SLYRGLTTHLVRQIPNTA 295
I+YP V R + GT F + L++ + YG LYRGL+ + +R IP+ A
Sbjct: 257 ISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQA 316
Query: 296 IMMATYELV 304
+ TYEL+
Sbjct: 317 VAFTTYELM 325
Score = 35.0 bits (79), Expect = 0.085
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 16/103 (15%)
Query: 6 TLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPL 65
T V+L GG G + ++ P +V + R+Q +V + TM
Sbjct: 240 THVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCL--TMRDT----------- 286
Query: 66 HCLKVILEKEGPR-SLFRGLGPNLVGVAPSRAIYFAAYSNCKE 107
+K + G R L+RGL N + PS+A+ F Y K+
Sbjct: 287 --MKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 86.3 bits (212), Expect = 3e-17
Identities = 77/308 (25%), Positives = 127/308 (41%), Gaps = 28/308 (9%)
Query: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLH 66
L +L AGG GG + PL+ VK RLQ+ +L + G
Sbjct: 11 LKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYS-------------GTFD 57
Query: 67 CLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAA 126
C + L +EG L+RG+ ++GV P A+ F + K KL D + AA
Sbjct: 58 CFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGK-KLQQKHPEDVLSYPQLFAA 116
Query: 127 --MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRG-MSAS 183
++G P IK LQ+ A + + G +C +K+YQ G++G Y+G +
Sbjct: 117 GMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTL 176
Query: 184 YAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTI 243
+ + ++F+ YE +K + + E + A G+ A
Sbjct: 177 MRDVPASGMYFMTYEWLK-NIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIP------ 229
Query: 244 AYPHVVRTRLR--EEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 301
P V+++R + G F L L+++EG SLY+G ++R P A +
Sbjct: 230 --PDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGF 287
Query: 302 ELVVYLLN 309
E+ + LN
Sbjct: 288 EVAMKFLN 295
>gi|116235466 solute carrier family 25, member 45 isoform b [Homo
sapiens]
Length = 246
Score = 85.9 bits (211), Expect = 4e-17
Identities = 58/200 (29%), Positives = 97/200 (48%), Gaps = 15/200 (7%)
Query: 2 SQRDTLVHLFAGGC-GGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
+Q + +H+F GC GG + A P +++K RLQ+ + + G+ R
Sbjct: 52 AQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQN--------QTEPRAQPGSPPPRY- 102
Query: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSN-CKEKLNDVFDPDSTQ 119
GP+HC I +EGPR LFRG + P+ IYF Y C++ + +P S
Sbjct: 103 -QGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSAT 161
Query: 120 VHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRG 179
V +++ AG + A P+ +IK+R+Q+D R G +C+ + +GL F+RG
Sbjct: 162 V-LVAGGFAGIASWVAATPLDMIKSRMQMDGLRR-RVYQGMLDCMVSSIRQEGLGVFFRG 219
Query: 180 MSASYA-GISETVIHFVIYE 198
++ + A + F+ YE
Sbjct: 220 VTINSARAFPVNAVTFLSYE 239
Score = 66.2 bits (160), Expect = 3e-11
Identities = 60/251 (23%), Positives = 103/251 (41%), Gaps = 28/251 (11%)
Query: 71 ILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVF------DPDSTQVHMIS 124
I E F+G+ + +A ++ F YSN L P S ++
Sbjct: 4 IYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLA 63
Query: 125 AAMAGFTAITATNPIWLIKTRLQLDARNRGE------RRMGAFECVRKVYQTDGLKGFYR 178
GF P LIK RLQ R + R G C +++ +G +G +R
Sbjct: 64 GCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFR 123
Query: 179 GMSASYAGISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSK 237
G A + TV I+F+ YE + ++ T +V A F G+ S
Sbjct: 124 GAWALTLRDTPTVGIYFITYEGLCRQY----TPEGQNPSSATVLVAGGFAGI-----ASW 174
Query: 238 TCATTIAYPHVVRTRLREEGTKYRSFFQTLSLLV---QEEGYGSLYRGLTTHLVRQIPNT 294
AT + ++++R++ +G + R + L +V ++EG G +RG+T + R P
Sbjct: 175 VAATPL---DMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVN 231
Query: 295 AIMMATYELVV 305
A+ +YE ++
Sbjct: 232 AVTFLSYEYLL 242
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 17/148 (11%)
Query: 166 KVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASD 225
K+Y+ + L GF++GMS A I+ V++ V++ LL T + +E +
Sbjct: 3 KIYRHESLLGFFKGMSFPIASIA--VVNSVLFGVYSNTLL----VLTATSHQERRAQPPS 56
Query: 226 FVGMMLAAATSKTC-ATTIAYPHVVRTRLREE----------GTKYRSFFQTLSLLVQEE 274
++ + LA T A +A +++ RL+ + +Y+ + + +EE
Sbjct: 57 YMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREE 116
Query: 275 GYGSLYRGLTTHLVRQIPNTAIMMATYE 302
G L+RG +R P I TYE
Sbjct: 117 GPRGLFRGAWALTLRDTPTVGIYFITYE 144
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 85.9 bits (211), Expect = 4e-17
Identities = 58/200 (29%), Positives = 97/200 (48%), Gaps = 15/200 (7%)
Query: 2 SQRDTLVHLFAGGC-GGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
+Q + +H+F GC GG + A P +++K RLQ+ + + G+ R
Sbjct: 94 AQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQN--------QTEPRAQPGSPPPRY- 144
Query: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSN-CKEKLNDVFDPDSTQ 119
GP+HC I +EGPR LFRG + P+ IYF Y C++ + +P S
Sbjct: 145 -QGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSAT 203
Query: 120 VHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRG 179
V +++ AG + A P+ +IK+R+Q+D R G +C+ + +GL F+RG
Sbjct: 204 V-LVAGGFAGIASWVAATPLDMIKSRMQMDGLRR-RVYQGMLDCMVSSIRQEGLGVFFRG 261
Query: 180 MSASYA-GISETVIHFVIYE 198
++ + A + F+ YE
Sbjct: 262 VTINSARAFPVNAVTFLSYE 281
Score = 77.8 bits (190), Expect = 1e-14
Identities = 75/310 (24%), Positives = 124/310 (40%), Gaps = 49/310 (15%)
Query: 12 AGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVI 71
AG G +G +L P + VK RLQ+ T Y G + C+ I
Sbjct: 8 AGWISGALGLVLGHPFDTVKVRLQTQ--TTY-------------------RGIVDCMVKI 46
Query: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVF------DPDSTQVHMISA 125
E F+G+ + +A ++ F YSN L P S ++
Sbjct: 47 YRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAG 106
Query: 126 AMAGFTAITATNPIWLIKTRLQLDARNRGE------RRMGAFECVRKVYQTDGLKGFYRG 179
GF P LIK RLQ R + R G C +++ +G +G +RG
Sbjct: 107 CTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRG 166
Query: 180 MSASYAGISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKT 238
A + TV I+F+ YE + ++ T +V A F G+ S
Sbjct: 167 AWALTLRDTPTVGIYFITYEGLCRQY----TPEGQNPSSATVLVAGGFAGI-----ASWV 217
Query: 239 CATTIAYPHVVRTRLREEGTKYRSFFQTLSLLV---QEEGYGSLYRGLTTHLVRQIPNTA 295
AT + ++++R++ +G + R + L +V ++EG G +RG+T + R P A
Sbjct: 218 AATPL---DMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNA 274
Query: 296 IMMATYELVV 305
+ +YE ++
Sbjct: 275 VTFLSYEYLL 284
Score = 52.4 bits (124), Expect = 5e-07
Identities = 45/191 (23%), Positives = 83/191 (43%), Gaps = 22/191 (11%)
Query: 123 ISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSA 182
++ ++G + +P +K RLQ RG +C+ K+Y+ + L GF++GMS
Sbjct: 7 VAGWISGALGLVLGHPFDTVKVRLQTQTTYRG-----IVDCMVKIYRHESLLGFFKGMSF 61
Query: 183 SYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTC-AT 241
A I+ V++ V++ LL T + +E + ++ + LA T A
Sbjct: 62 PIASIA--VVNSVLFGVYSNTLL----VLTATSHQERRAQPPSYMHIFLAGCTGGFLQAY 115
Query: 242 TIAYPHVVRTRLREE----------GTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQI 291
+A +++ RL+ + +Y+ + + +EEG L+RG +R
Sbjct: 116 CLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDT 175
Query: 292 PNTAIMMATYE 302
P I TYE
Sbjct: 176 PTVGIYFITYE 186
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 80.9 bits (198), Expect = 1e-15
Identities = 86/339 (25%), Positives = 139/339 (41%), Gaps = 59/339 (17%)
Query: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASV---------N 57
L + A G G V ++ PL+VVK RLQS ++ + + + S N
Sbjct: 12 LQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKWKCLLYCN 71
Query: 58 RVVSP---------------------GPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRA 96
V+ P G + I+ EG R+L+ GL LV P+ A
Sbjct: 72 GVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATA 131
Query: 97 IYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGER 156
IYF AY K L M++ A+A +T +P+ L++T+LQ A++ R
Sbjct: 132 IYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQ--AQHVSYR 189
Query: 157 RMGAFECVRKVYQTDGLKGFYRGMS-ASYAGISETVIHFVIYESIKQKLLEYKTASTMEN 215
+GA CVR G + + G + + + +++ YE +K L ++
Sbjct: 190 ELGA--CVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFR-----PK 242
Query: 216 DEESVKEASDFVGM-MLAAATSKTCATTIAYP-HVVRTR----------LREEGTKYRSF 263
D+ S VGM +A S T A + P VV+T+ +R S
Sbjct: 243 DQTS-------VGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDST 295
Query: 264 FQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
+ L + E G L+ G +++ P+ AIM++TYE
Sbjct: 296 WLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 156 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME 214
R G + K+ + +G + + G+ A+ + T I+F Y+ +K L S
Sbjct: 95 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTS--- 151
Query: 215 NDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKYRSFFQTLSLLVQE 273
D M+A A ++ T+ P ++RT+L+ + YR + V +
Sbjct: 152 ----------DLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQ 201
Query: 274 EGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 310
G+ SL+ G +R +P +A+ YELV LNG
Sbjct: 202 GGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNG 238
Score = 31.2 bits (69), Expect = 1.2
Identities = 16/56 (28%), Positives = 27/56 (48%)
Query: 255 EEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 310
++ T++ +V+ EG +L+ GL LV +P TAI Y+ + L G
Sbjct: 91 QDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCG 146
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 80.5 bits (197), Expect = 2e-15
Identities = 89/347 (25%), Positives = 138/347 (39%), Gaps = 67/347 (19%)
Query: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSS-----------------SVTLYISEVQLN 49
L + A G G V ++ PL+VVK RLQS S T S +Q
Sbjct: 12 LQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQST 71
Query: 50 TMAGASVNRVVSP---------------------GPLHCLKVILEKEGPRSLFRGLGPNL 88
N V+ P G + I+ EG R+L+ GL L
Sbjct: 72 GKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL 131
Query: 89 VGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQL 148
V P+ AIYF AY K L M++ A+A +T +P+ L++T+LQ
Sbjct: 132 VMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQ- 190
Query: 149 DARNRGERRMGAFECVRKVYQTDGLKGFYRGMS-ASYAGISETVIHFVIYESIKQKLLEY 207
A++ R +GA CVR G + + G + + + +++ YE +K L +
Sbjct: 191 -AQHVSYRELGA--CVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGF 247
Query: 208 KTASTMENDEESVKEASDFVGM-MLAAATSKTCATTIAYP-HVVRTR----------LRE 255
+ D+ S VGM +A S T A + P VV+T+ +R
Sbjct: 248 R-----PKDQTS-------VGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRV 295
Query: 256 EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
S + L + E G L+ G +++ P+ AIM++TYE
Sbjct: 296 NPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 156 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME 214
R G + K+ + +G + + G+ A+ + T I+F Y+ +K L S
Sbjct: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTS--- 159
Query: 215 NDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKYRSFFQTLSLLVQE 273
D M+A A ++ T+ P ++RT+L+ + YR + V +
Sbjct: 160 ----------DLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQ 209
Query: 274 EGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 310
G+ SL+ G +R +P +A+ YELV LNG
Sbjct: 210 GGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNG 246
Score = 31.2 bits (69), Expect = 1.2
Identities = 16/56 (28%), Positives = 27/56 (48%)
Query: 255 EEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 310
++ T++ +V+ EG +L+ GL LV +P TAI Y+ + L G
Sbjct: 99 QDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCG 154
>gi|5453918 solute carrier family 25 (mitochondrial carrier;
peroxisomal membrane protein, 34kDa), member 17 [Homo
sapiens]
Length = 307
Score = 80.1 bits (196), Expect = 2e-15
Identities = 76/315 (24%), Positives = 133/315 (42%), Gaps = 50/315 (15%)
Query: 5 DTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGP 64
++LVH AG G + PL+ + RLQ ++ + +V
Sbjct: 8 ESLVHAVAGAVGSVTAMTVFFPLDTARLRLQ------------VDEKRKSKTTHMV---- 51
Query: 65 LHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMIS 124
L I+++EG + +RG P + + S +YF +++ K L +T ++
Sbjct: 52 ---LLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKA-LWVKGQHSTTGKDLVV 107
Query: 125 AAMAGFTAITATNPIWLIKTRLQLD-ARNRGE-----RRMGAFECVRKVYQTDGLKGFYR 178
+AG + T P+W++ TRL+L A+ R E G + ++ + +G+ +
Sbjct: 108 GFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWN 167
Query: 179 GMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKT 238
G S + I F+ YE +K++LL ++ +K +S + + + A +K
Sbjct: 168 GTFPSLLLVFNPAIQFMFYEGLKRQLL-----------KKRMKLSS--LDVFIIGAVAKA 214
Query: 239 CATTIAYP--------HVVRTRLREEGTKYRSFFQTLSLL---VQEEGYGSLYRGLTTHL 287
ATT+ YP R RL E S L LL V+ G LY+GL L
Sbjct: 215 IATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKL 274
Query: 288 VRQIPNTAIMMATYE 302
++ + A+M YE
Sbjct: 275 LQTVLTAALMFLVYE 289
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 79.3 bits (194), Expect = 4e-15
Identities = 77/321 (23%), Positives = 136/321 (42%), Gaps = 39/321 (12%)
Query: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISE--VQLNTMA--------GASV 56
L + A G + +++ PL+VVK RLQ+ + L + V N + G +
Sbjct: 16 LQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNK 75
Query: 57 NRVVSPG----PLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDV 112
PG L I+ EG +SL+ GL P LV P+ IYF Y L
Sbjct: 76 LWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSK 135
Query: 113 FDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDG 172
+ T + +++ +A F A+T +P+ LI+T++Q ++ + V K DG
Sbjct: 136 LGENETCIPIVAGIVARFGAVTVISPLELIRTKMQ----SKKFSYVELHRFVSKKVSEDG 191
Query: 173 LKGFYRGMSAS-YAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMML 231
+RG + + + + +++ YE +K+ L E + + E + +
Sbjct: 192 WISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCE----------KSGLYEPTFMINFTS 241
Query: 232 AAATSKTCATTIAYPHVVRTRLREEGTKYRSFFQTLSL----------LVQEEGYGSLYR 281
A + A VV+T+ + + Y S ++ L +V + G+ L+
Sbjct: 242 GALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFS 301
Query: 282 GLTTHLVRQIPNTAIMMATYE 302
GL L++ P AIM++TYE
Sbjct: 302 GLIPRLIKIAPACAIMISTYE 322
Score = 49.3 bits (116), Expect = 4e-06
Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 15/148 (10%)
Query: 159 GAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTMENDE 217
G + K+ + +G+K + G+ + + TVI+F Y+ + L S + +E
Sbjct: 86 GTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL-----RSKLGENE 140
Query: 218 ESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKYRSFFQTLSLLVQEEGY 276
+ ++A ++ A T+ P ++RT+++ + Y + +S V E+G+
Sbjct: 141 TCIP--------IVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGW 192
Query: 277 GSLYRGLTTHLVRQIPNTAIMMATYELV 304
SL+RG ++R +P +A+ YE++
Sbjct: 193 ISLWRGWAPTVLRDVPFSAMYWYNYEIL 220
Score = 45.1 bits (105), Expect = 8e-05
Identities = 40/189 (21%), Positives = 82/189 (43%), Gaps = 30/189 (15%)
Query: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
+ + +T + + AG + PLE+++T++QS S V+L+ V+
Sbjct: 136 LGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKK----FSYVELHRFVSKKVS--- 188
Query: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL---NDVFDPDS 117
++G SL+RG P ++ P A+Y+ Y K+ L + +++P +
Sbjct: 189 -------------EDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEP-T 234
Query: 118 TQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERR------MGAFECVRKVYQTD 171
++ S A++G A AT P ++KT+ Q + M + ++ + +
Sbjct: 235 FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKN 294
Query: 172 GLKGFYRGM 180
G G + G+
Sbjct: 295 GFSGLFSGL 303
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 79.0 bits (193), Expect = 5e-15
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 26/220 (11%)
Query: 3 QRDTLVHLFAGGCG-GTVGAILTCPLEVVKTRLQ-----SSSVTLYISEVQLNTMAGA-- 54
Q+ TL+ GCG GT I+T P+E++K +LQ ++ + ++ QL+ GA
Sbjct: 99 QKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQP 158
Query: 55 SVNRVVSPGPL--HCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDV 112
SV +P P + +L G L++GLG L+ P +YF ++N LN +
Sbjct: 159 SVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFAN----LNQL 214
Query: 113 FDPDSTQ-----VHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGE-RRMGAFECVRK 166
P S + V ++ +AG A A NP ++KTRLQ R E G +C RK
Sbjct: 215 GRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARK 274
Query: 167 VYQTDGLKGFYRG------MSASYAGISETVIHFVIYESI 200
+ + +G F +G + A GI++ V I ES+
Sbjct: 275 ILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESL 314
Score = 61.2 bits (147), Expect = 1e-09
Identities = 72/326 (22%), Positives = 122/326 (37%), Gaps = 61/326 (18%)
Query: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
L GG G +G P+++ KTRLQ N G V +S CL
Sbjct: 12 LINGGIAGLIGVTCVFPIDLAKTRLQ-------------NQQNGQRVYTSMS----DCLI 54
Query: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
+ EG ++RG NL V P +AI AA + +L+ + M++ AG
Sbjct: 55 KTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAG 114
Query: 130 FTAITATNPIWLIKTRLQLDARNRGER-------------------------RMGAFECV 164
+ T P+ ++K +LQ R +R R A +
Sbjct: 115 TCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLT 174
Query: 165 RKVYQTDGLKGFYRGMSAS-YAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEA 223
R + ++ G+ G Y+G+ A+ + +V++F ++ ++ Q + +E
Sbjct: 175 RDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQL------------GRPASEEK 222
Query: 224 SDFVGMMLAAATSKTCATTIAYP-HVVRTRLR--EEGTK---YRSFFQTLSLLVQEEGYG 277
S F LA + + A P VV+TRL+ + G Y +++ EG
Sbjct: 223 SPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPS 282
Query: 278 SLYRGLTTHLVRQIPNTAIMMATYEL 303
+ +G + P I Y L
Sbjct: 283 AFLKGAYCRALVIAPLFGIAQVVYFL 308
Score = 38.9 bits (89), Expect = 0.006
Identities = 45/211 (21%), Positives = 82/211 (38%), Gaps = 45/211 (21%)
Query: 117 STQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGF 176
S +I+ +AG +T PI L KTRLQ + +N +C+ K +++G G
Sbjct: 7 SLPAKLINGGIAGLIGVTCVFPIDLAKTRLQ-NQQNGQRVYTSMSDCLIKTVRSEGYFGM 65
Query: 177 YRGMSASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT 235
YRG + + ++ E I + + +L + T+ +KE MLA
Sbjct: 66 YRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTL------LKE-------MLAGCG 112
Query: 236 SKTCATTIAYP-HVVRTRLREEG-----------------------------TKYRSFFQ 265
+ TC + P +++ +L++ G + Q
Sbjct: 113 AGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQ 172
Query: 266 TLSLLVQEEGYGSLYRGLTTHLVRQIPNTAI 296
L++ G LY+GL L+R +P + +
Sbjct: 173 LTRDLLRSRGIAGLYKGLGATLLRDVPFSVV 203
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 6/82 (7%)
Query: 231 LAAATSKTCATTIAYPHVVRTRLREEGTK---YRSFFQTLSLLVQEEGYGSLYRGLTTHL 287
+A TC I + +TRL+ + Y S L V+ EGY +YRG +L
Sbjct: 17 IAGLIGVTCVFPI---DLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNL 73
Query: 288 VRQIPNTAIMMATYELVVYLLN 309
P AI +A + + L+
Sbjct: 74 TLVTPEKAIKLAANDFFRHQLS 95
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 78.2 bits (191), Expect = 9e-15
Identities = 82/310 (26%), Positives = 139/310 (44%), Gaps = 42/310 (13%)
Query: 4 RDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPG 63
R+ + AGG G V L PL+VVKTR Q +Q S +V
Sbjct: 11 REASRQIVAGGSAGLVEICLMHPLDVVKTRFQ----------IQRCATDPNSYKSLVDS- 59
Query: 64 PLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDV-FDPDSTQVHM 122
++I + EG ++G+ P ++ P RA+ F + K+ L V P T
Sbjct: 60 ----FRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALT--FA 113
Query: 123 ISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDG--LKGFYRGM 180
I+ +G T NP ++K LQ + RN + R++ + +G L+G +G+
Sbjct: 114 IAGLGSGLTEAIVVNPFEVVKVGLQAN-RNTFAEQPSTVGYARQIIKKEGWGLQGLNKGL 172
Query: 181 SASYA--GISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKT 238
+A+ G+ +++F Y ++K + K + + E G+ L S T
Sbjct: 173 TATLGRHGVFN-MVYFGFYYNVKNMIPVNK---------DPILEFWRKFGIGLL---SGT 219
Query: 239 CATTIAYPH-VVRTRLREEGT-----KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIP 292
A+ I P V ++R++ KYR+ F+T++ + QEEG +LY+GL ++R P
Sbjct: 220 IASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGP 279
Query: 293 NTAIMMATYE 302
A+M+ YE
Sbjct: 280 GGAVMLLVYE 289
Score = 41.2 bits (95), Expect = 0.001
Identities = 48/184 (26%), Positives = 72/184 (39%), Gaps = 21/184 (11%)
Query: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
+S L AG G AI+ P EVVK LQ++ NT A
Sbjct: 104 VSLSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQANR----------NTFA-------E 146
Query: 61 SPGPLHCLKVILEKE--GPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDST 118
P + + I++KE G + L +GL L +YF Y N K + DP
Sbjct: 147 QPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILE 206
Query: 119 QVHMISAAMAGFTAITATN-PIWLIKTRLQLDARNRGE-RRMGAFECVRKVYQTDGLKGF 176
+ T + N P + K+R+Q GE + F+ + VYQ +G+
Sbjct: 207 FWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILAL 266
Query: 177 YRGM 180
Y+G+
Sbjct: 267 YKGL 270
Score = 31.6 bits (70), Expect = 0.94
Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 9/95 (9%)
Query: 220 VKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLR-----EEGTKYRSFFQTLSLLVQE 273
V+EAS ++A ++ + +P VV+TR + + Y+S + ++ Q
Sbjct: 10 VREASR---QIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQM 66
Query: 274 EGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 308
EG Y+G+ ++ + P A+ T+E LL
Sbjct: 67 EGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLL 101
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,437,834
Number of Sequences: 37866
Number of extensions: 411355
Number of successful extensions: 1454
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 854
Number of HSP's gapped (non-prelim): 218
length of query: 310
length of database: 18,247,518
effective HSP length: 102
effective length of query: 208
effective length of database: 14,385,186
effective search space: 2992118688
effective search space used: 2992118688
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.