Search of human proteins with 156105687

Search of human proteins with 156105687

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156105687 mitochondrial intermediate peptidase [Homo
sapiens]
         (713 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156105687 mitochondrial intermediate peptidase [Homo sapiens]     1441   0.0  
gi|4507491 thimet oligopeptidase 1 [Homo sapiens]                     198   1e-50
gi|14149738 neurolysin [Homo sapiens]                                 184   3e-46
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...    35   0.32 
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ...    32   2.0  
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa...    31   3.5  
gi|239755232 PREDICTED: hypothetical protein [Homo sapiens]            30   7.8  
gi|239749768 PREDICTED: hypothetical protein [Homo sapiens]            30   7.8  
gi|239744027 PREDICTED: hypothetical protein XP_002343007 [Homo ...    30   7.8  
gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform...    30   7.8  

>gi|156105687 mitochondrial intermediate peptidase [Homo sapiens]
          Length = 713

 Score = 1441 bits (3729), Expect = 0.0
 Identities = 713/713 (100%), Positives = 713/713 (100%)

Query: 1   MLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG 60
           MLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
Sbjct: 1   MLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG 60

Query: 61  ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVAD 120
           ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVAD
Sbjct: 61  ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVAD 120

Query: 121 LADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPETR 180
           LADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPETR
Sbjct: 121 LADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPETR 180

Query: 181 RVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR 240
           RVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
Sbjct: 181 RVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR 240

Query: 241 NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYST 300
           NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYST
Sbjct: 241 NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYST 300

Query: 301 FSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMKMKLNPQNSEVMPWDPPY 360
           FSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMKMKLNPQNSEVMPWDPPY
Sbjct: 301 FSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMKMKLNPQNSEVMPWDPPY 360

Query: 361 YSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL 420
           YSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL
Sbjct: 361 YSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL 420

Query: 421 AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRS 480
           AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRS
Sbjct: 421 AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRS 480

Query: 481 SPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFANDYRVV 540
           SPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFANDYRVV
Sbjct: 481 SPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFANDYRVV 540

Query: 541 NQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL 600
           NQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL
Sbjct: 541 NQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL 600

Query: 601 KETQEKFYGLPYVPNTAWQLRFSHLVGYGARYYSYLMSRAVASMVWKECFLQDPFNRAAG 660
           KETQEKFYGLPYVPNTAWQLRFSHLVGYGARYYSYLMSRAVASMVWKECFLQDPFNRAAG
Sbjct: 601 KETQEKFYGLPYVPNTAWQLRFSHLVGYGARYYSYLMSRAVASMVWKECFLQDPFNRAAG 660

Query: 661 ERYRREMLAHGGGREPMLMVEGMLQKCPSVDDFVSALVSDLDLDFETFLMDSE 713
           ERYRREMLAHGGGREPMLMVEGMLQKCPSVDDFVSALVSDLDLDFETFLMDSE
Sbjct: 661 ERYRREMLAHGGGREPMLMVEGMLQKCPSVDDFVSALVSDLDLDFETFLMDSE 713


>gi|4507491 thimet oligopeptidase 1 [Homo sapiens]
          Length = 689

 Score =  198 bits (504), Expect = 1e-50
 Identities = 161/605 (26%), Positives = 271/605 (44%), Gaps = 42/605 (6%)

Query: 120 DLADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPET 179
           ++ DF +   P    R A+ EA + +     +++   D+YQ +   L +K   DSL PE 
Sbjct: 80  NILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIV-WLQEKVQKDSLRPEA 138

Query: 180 RRVAELFMFDFEISGIHLDKEKRKR-----------AVDLNVKILDLSSTFLMGT----- 223
            R  E  +     +G+HL +E ++             +D N K L+  +TFL  T     
Sbjct: 139 ARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFN-KNLNEDTTFLPFTLQELG 197

Query: 224 ----NFPNKIEKHLLPEHIRRNFTSAGDHI--IIDGLHAESPDDLVREAAYKIFLYPNAG 277
               +F N +EK    E  +   T    H   ++   H       V EA        N  
Sbjct: 198 GLPEDFLNSLEKM---EDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCA 254

Query: 278 QLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFE 337
            LK   EL++ R   ++L+G+ T +   L+  +AK  +TV  FL++L+ KL     ++  
Sbjct: 255 ILK---ELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERA 311

Query: 338 MIRGMKM-----KLNPQNSEVMPWDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNI 392
           +I  +K      +  P +  +  WD  YY   +   RY ++ +L   +F +     GL  
Sbjct: 312 VILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLG 371

Query: 393 LLNRLLGISLYAEQPAKGEVWSEDVRKLAVVHESEG-LLGYIYCDFFQRADKPHQDCHFT 451
           +   LLG++ + E+ A    W EDVR       + G ++G  Y D + R  K      F 
Sbjct: 372 IYQELLGLAFHHEEGASA--WHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFG 429

Query: 452 IRGGRLKEDGDYQLPVVVLMLNLPRSSRSSPTLLTPGMMENLFHEMGHAMHSMLGRTRYQ 511
           ++ G L++DG  Q+ +  ++ N  + +  +P+LL    +E  FHE GH MH +  +  + 
Sbjct: 430 LQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFA 489

Query: 512 HVTGTRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAA 571
             +GT    DF E PS ++E +  +   + + +RHY+TG  +P+ ++ +L ES++     
Sbjct: 490 MFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGL 549

Query: 572 DMQLQVFYATLDQIYHGKHPLRNSTTDILKETQEKFYGLPYVPNTAWQLRFSHLV-GYGA 630
               Q+  A +DQ  H +    +   +  +  QE   G+P  P T     F HL  GY A
Sbjct: 550 FNLRQIVLAKVDQALHTQTD-ADPAEEYARLCQE-ILGVPATPGTNMPATFGHLAGGYDA 607

Query: 631 RYYSYLMSRAVASMVWKECFLQD-PFNRAAGERYRREMLAHGGGREPMLMVEGMLQKCPS 689
           +YY YL S   +  ++   F Q+   N   G  YR  +L  GG  +   M+   L + P 
Sbjct: 608 QYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPK 667

Query: 690 VDDFV 694
            D F+
Sbjct: 668 QDAFL 672


>gi|14149738 neurolysin [Homo sapiens]
          Length = 704

 Score =  184 bits (466), Expect = 3e-46
 Identities = 167/619 (26%), Positives = 268/619 (43%), Gaps = 72/619 (11%)

Query: 121 LADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPETR 180
           + DF +    +   R A+ EA + +     +++   D+++ +  L     L   + PE R
Sbjct: 105 MLDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIVHLQETCDL-GKIKPEAR 163

Query: 181 RVAELFMFDFEISGIHLD-------KEKRKRAVDLNV---KILDLSSTFLMGTNFPNKIE 230
           R  E  +   + +G+HL        K  +KR  +L +   K L+   TFL+     +K E
Sbjct: 164 RYLEKSIKMGKRNGLHLPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVF----SKAE 219

Query: 231 KHLLPEHIRRNFTSAGDHIIIDGLHAESPDDLVREAAYKIFL-YPN-------------- 275
              LP+              ID L  E  DD      YKI L YP+              
Sbjct: 220 LGALPDD------------FIDSL--EKTDD----DKYKITLKYPHYFPVMKKCCIPETR 261

Query: 276 -----AGQLKC-------LEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEK 323
                A   +C       L++LL  R  +AKL+GYST +   L+   AK+   V  FL+ 
Sbjct: 262 RRMEMAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDD 321

Query: 324 LSDKLSERTLKDFEMIRGMKMKLNPQ-----NSEVMPWDPPYYSGVIRAERYNIEPSLYC 378
           LS KL      + E I  +K K         + ++  WD  YY       +Y+I+     
Sbjct: 322 LSQKLKPLGEAEREFILNLKKKECKDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLK 381

Query: 379 PFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKLAVVHESEG-LLGYIYCDF 437
            +F +    EGL      LLG+S   EQ     VW++ V    V  ++ G +LG  Y D 
Sbjct: 382 EYFPIEVVTEGLLNTYQELLGLSF--EQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDL 439

Query: 438 FQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRSSPTLLTPGMMENLFHEM 497
           + R  K +    F ++ G L  DG   + V  L++N  +     P+LL    +   FHE 
Sbjct: 440 YPREGKYNHAACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEF 499

Query: 498 GHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNM 557
           GH MH +  +T +   +GT   TDF EVPS ++E +  D   + + ++HY+ G P+  ++
Sbjct: 500 GHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDL 559

Query: 558 VSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDILKETQEKFYGLPYVPNTA 617
           + +L  S+ V        Q+  + +DQ  H    L ++ ++  K   E   G+   P T 
Sbjct: 560 LEKLVASRLVNTGLLTLRQIVLSKVDQSLHTNTSL-DAASEYAKYCSE-ILGVAATPGTN 617

Query: 618 WQLRFSHLV-GYGARYYSYLMSRAVASMVWKECFLQDP-FNRAAGERYRREMLAHGGGRE 675
               F HL  GY  +YY YL S   +  ++  CF ++   N   G +YR  +L  GG  +
Sbjct: 618 MPATFGHLAGGYDGQYYGYLWSEVFSMDMFYSCFKKEGIMNPEVGMKYRNLILKPGGSLD 677

Query: 676 PMLMVEGMLQKCPSVDDFV 694
            M M+   L++ P+   F+
Sbjct: 678 GMDMLHNFLKREPNQKAFL 696


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 29/136 (21%)

Query: 183 AELFMFDFEISGI-------HLDKEKRKRAVDLNVKILDLSSTFLMGTN--FPNKIEKHL 233
           AE+F  DF    I       H+ K+ + + VD+ ++ LDL +  ++  +  F  K EK  
Sbjct: 176 AEVFSTDFSNPSIAQARINSHVKKKTQGKVVDI-IQGLDLLTAMVLVNHIFFKAKWEKPF 234

Query: 234 LPEHIRRNFT-SAGDHIIID------------GLHAESPDDLVREAAYK-----IFLYPN 275
            PE+ R+NF    G+ + +             G+  E  +  V +  YK      F+ P+
Sbjct: 235 HPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTEL-NCFVLQMDYKGDAVAFFVLPS 293

Query: 276 AGQLKCLEELLSSRDL 291
            G+++ LE+ LS+R L
Sbjct: 294 KGKMRQLEQALSARTL 309


>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           B [Homo sapiens]
          Length = 335

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 31/116 (26%), Positives = 57/116 (49%), Gaps = 22/116 (18%)

Query: 196 HLDKEKRKRAVDLNVKILDLSSTFLMGTN--FPNKIEKHLLPEHIRRNFT-SAGDHIIID 252
           H+ K+ + + VD+ ++ LDL +  ++  +  F  K EK   PE+ R+NF    G+ + + 
Sbjct: 96  HVKKKTQGKVVDI-IQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 154

Query: 253 ------------GLHAESPDDLVREAAYK-----IFLYPNAGQLKCLEELLSSRDL 291
                       G+  E  +  V +  YK      F+ P+ G+++ LE+ LS+R L
Sbjct: 155 VPMMHQKEQFAFGVDTEL-NCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTL 209


>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
           sapiens]
          Length = 1181

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 30/124 (24%), Positives = 49/124 (39%), Gaps = 14/124 (11%)

Query: 101 GPQTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTN----V 156
           G QT       S  + +     + +K  H E     A++   R IG +V  LNTN    +
Sbjct: 653 GAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGL 712

Query: 157 DLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISG-------IHLDKEKRKRAVDLN 209
             Y       A+ KLVD   P        F++  ++ G        H  K+ ++ A D  
Sbjct: 713 LEYARSHGFAAEFKLVDQSGPPHE---PKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAA 769

Query: 210 VKIL 213
           +++L
Sbjct: 770 LRVL 773


>gi|239755232 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 501

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 18  PPRRAGRGSLEAGIRARRVSTSWSPV---GAAFNVKPQGSRLDLFGERR 63
           PPR      LEAG R RR +    PV   G++F  +P    L L  +RR
Sbjct: 319 PPRAPRLRRLEAGRRLRRTAAPLGPVAGAGSSFGGRPHRPSLALGSDRR 367


>gi|239749768 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 591

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 18  PPRRAGRGSLEAGIRARRVSTSWSPV---GAAFNVKPQGSRLDLFGERR 63
           PPR      LEAG R RR +    PV   G++F  +P    L L  +RR
Sbjct: 409 PPRAPRLRRLEAGRRLRRTAAPLGPVAGAGSSFGGRPHRPSLALGSDRR 457


>gi|239744027 PREDICTED: hypothetical protein XP_002343007 [Homo
           sapiens]
          Length = 591

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 18  PPRRAGRGSLEAGIRARRVSTSWSPV---GAAFNVKPQGSRLDLFGERR 63
           PPR      LEAG R RR +    PV   G++F  +P    L L  +RR
Sbjct: 409 PPRAPRLRRLEAGRRLRRTAAPLGPVAGAGSSFGGRPHRPSLALGSDRR 457


>gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform b
           [Homo sapiens]
          Length = 807

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 44/219 (20%), Positives = 90/219 (41%), Gaps = 23/219 (10%)

Query: 178 ETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPN-KIEKHLLPE 236
           E  + AE   ++ +++ +   K       D +V   ++SS   M  N  + K+EK  +  
Sbjct: 219 EKAKKAEQMEYERQVASL---KAANAAENDFSVSQAEMSSRQAMLENASDIKLEKFSISA 275

Query: 237 HIRRNFTSAGDHII------IDGLHAESPDDLVREAAYK-IFLYPNAGQLKCLEELLSSR 289
           H +  F +A  +I+      + G + +    L++  A + + + PN   L C +E+++  
Sbjct: 276 HGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADE 335

Query: 290 DLLAKLVGYSTFSH-------RALQGTIAKNPETVMQFLEKLSDKL-----SERTLKDFE 337
               + V  +           R LQG + +  +T  + LEK+ ++L     +    K   
Sbjct: 336 TPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAEAKARR 395

Query: 338 MIRGMKMKLNPQNSEVMPWDPPYYSGVIRAERYNIEPSL 376
           ++ G+      QN     +   +   V  A    +EP+L
Sbjct: 396 ILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTL 434


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,715,618
Number of Sequences: 37866
Number of extensions: 1269718
Number of successful extensions: 2881
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2866
Number of HSP's gapped (non-prelim): 11
length of query: 713
length of database: 18,247,518
effective HSP length: 109
effective length of query: 604
effective length of database: 14,120,124
effective search space: 8528554896
effective search space used: 8528554896
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.