Guide to the Human Genome
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Search of human proteins with 15451933

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
         (383 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]                  797   0.0  
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]                  789   0.0  
gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]                  789   0.0  
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]                 520   e-147
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]                   515   e-146
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]                  515   e-146
gi|56786144 dual specificity phosphatase 23 [Homo sapiens]             59   6e-09
gi|30089952 protein tyrosine phosphatase domain containing 1 pro...    57   3e-08
gi|30089950 protein tyrosine phosphatase domain containing 1 pro...    57   3e-08
gi|14589856 protein tyrosine phosphatase type IVA, member 3 isof...    55   1e-07
gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo...    53   4e-07
gi|18104971 protein tyrosine phosphatase type IVA, member 2 isof...    51   2e-06
gi|169162376 PREDICTED: similar to protein tyrosine phosphatase ...    45   1e-04
gi|14589854 protein tyrosine phosphatase type IVA, member 3 isof...    45   1e-04
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             43   5e-04
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi...    43   5e-04
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi...    43   5e-04
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    43   5e-04
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    42   7e-04
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...    42   0.001
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...    42   0.001
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...    42   0.001
gi|73765544 phosphatase and tensin homolog [Homo sapiens]              42   0.001
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             41   0.002
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              40   0.005
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               39   0.008
gi|108802609 protein tyrosine phosphatase, non-receptor type 20 ...    39   0.008
gi|108802611 protein tyrosine phosphatase, non-receptor type 20 ...    39   0.008
gi|109138573 protein tyrosine phosphatase, non-receptor type 20A...    39   0.008
gi|109138565 protein tyrosine phosphatase, non-receptor type 20A...    39   0.008

>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
          Length = 383

 Score =  797 bits (2058), Expect = 0.0
 Identities = 383/383 (100%), Positives = 383/383 (100%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
Sbjct: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
Sbjct: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
Sbjct: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
Sbjct: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
Sbjct: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360
           HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
Sbjct: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360

Query: 361 DMSIGGNLSKTQNMERFGEVSFP 383
           DMSIGGNLSKTQNMERFGEVSFP
Sbjct: 361 DMSIGGNLSKTQNMERFGEVSFP 383


>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
          Length = 594

 Score =  789 bits (2037), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
Sbjct: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
Sbjct: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
Sbjct: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
Sbjct: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
Sbjct: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360
           HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
Sbjct: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360

Query: 361 DMSIGGNLSKTQNMERFGE 379
           DMSIGGNLSKTQNMERFGE
Sbjct: 361 DMSIGGNLSKTQNMERFGE 379


>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
          Length = 623

 Score =  789 bits (2037), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
Sbjct: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
Sbjct: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
Sbjct: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
Sbjct: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
Sbjct: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360
           HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
Sbjct: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360

Query: 361 DMSIGGNLSKTQNMERFGE 379
           DMSIGGNLSKTQNMERFGE
Sbjct: 361 DMSIGGNLSKTQNMERFGE 379


>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
          Length = 461

 Score =  520 bits (1338), Expect = e-147
 Identities = 236/368 (64%), Positives = 296/368 (80%), Gaps = 3/368 (0%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           M+ E        E +KDRL FA L +RPKS  N HYFSID EL YENFYADFGPLNLAMV
Sbjct: 1   MSREGAGAALVAEVIKDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCK+NKKLKS ++ RKKIVH+T  DQRK+ANAAFL+G Y VIYL +TPEEAYR L+ 
Sbjct: 61  YRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIF 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           G    Y+PFRDA++G+C + +T+LDC   ++K +Q+GF +F +F++DEYEHYE+ ENGD 
Sbjct: 121 GETS-YIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDL 179

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWI+P +F+AF GPH ++++E+GY  H+PE Y  YFK HNVT ++RLNK++Y+AKRFTDA
Sbjct: 180 NWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDA 239

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GF+H+DLFF DGSTP+D IV+ FL+ICEN EGAIAVHCKAGLGRTGTLIACY+MKHYR T
Sbjct: 240 GFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMT 299

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSE--GSINKILSG 358
            AE IAW+RICRPGS+IGPQQ FL  KQ +LW++GD FR KLK + + +   + +K+LSG
Sbjct: 300 AAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSG 359

Query: 359 LDDMSIGG 366
           +DD+SI G
Sbjct: 360 VDDISING 367


>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
          Length = 459

 Score =  515 bits (1326), Expect = e-146
 Identities = 232/352 (65%), Positives = 290/352 (82%), Gaps = 3/352 (0%)

Query: 17  DRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSL 76
           DRL FA L +RPKS  N HYFSID EL YENFYADFGPLNLAMVYRYCCK+NKKLKS ++
Sbjct: 54  DRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITM 113

Query: 77  SRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGN 136
            RKKIVH+T  DQRK+ANAAFL+G Y VIYL +TPEEAYR L+ G    Y+PFRDA++G+
Sbjct: 114 LRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETS-YIPFRDAAYGS 172

Query: 137 CTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPHP 196
           C + +T+LDC   ++K +Q+GF +F +F++DEYEHYE+ ENGD NWI+P +F+AF GPH 
Sbjct: 173 CNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHS 232

Query: 197 KSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPS 256
           ++++E+GY  H+PE Y  YFK HNVT ++RLNK++Y+AKRFTDAGF+H+DLFF DGSTP+
Sbjct: 233 RARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPT 292

Query: 257 DNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSI 316
           D IV+ FL+ICEN EGAIAVHCKAGLGRTGTLIACY+MKHYR T AE IAW+RICRPGS+
Sbjct: 293 DAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 352

Query: 317 IGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSE--GSINKILSGLDDMSIGG 366
           IGPQQ FL  KQ +LW++GD FR KLK + + +   + +K+LSG+DD+SI G
Sbjct: 353 IGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISING 404


>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
          Length = 498

 Score =  515 bits (1326), Expect = e-146
 Identities = 232/352 (65%), Positives = 290/352 (82%), Gaps = 3/352 (0%)

Query: 17  DRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSL 76
           DRL FA L +RPKS  N HYFSID EL YENFYADFGPLNLAMVYRYCCK+NKKLKS ++
Sbjct: 54  DRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITM 113

Query: 77  SRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGN 136
            RKKIVH+T  DQRK+ANAAFL+G Y VIYL +TPEEAYR L+ G    Y+PFRDA++G+
Sbjct: 114 LRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETS-YIPFRDAAYGS 172

Query: 137 CTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPHP 196
           C + +T+LDC   ++K +Q+GF +F +F++DEYEHYE+ ENGD NWI+P +F+AF GPH 
Sbjct: 173 CNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHS 232

Query: 197 KSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPS 256
           ++++E+GY  H+PE Y  YFK HNVT ++RLNK++Y+AKRFTDAGF+H+DLFF DGSTP+
Sbjct: 233 RARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPT 292

Query: 257 DNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSI 316
           D IV+ FL+ICEN EGAIAVHCKAGLGRTGTLIACY+MKHYR T AE IAW+RICRPGS+
Sbjct: 293 DAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 352

Query: 317 IGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSE--GSINKILSGLDDMSIGG 366
           IGPQQ FL  KQ +LW++GD FR KLK + + +   + +K+LSG+DD+SI G
Sbjct: 353 IGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISING 404


>gi|56786144 dual specificity phosphatase 23 [Homo sapiens]
          Length = 150

 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 21/147 (14%)

Query: 175 VENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEA 234
           V+  +F+W++PG+               G  L    A++ +     V  +V L ++    
Sbjct: 3   VQPPNFSWVLPGRLA-------------GLALPRLPAHYQFLLDLGVRHLVSLTER---G 46

Query: 235 KRFTDA--GFEHYDLFFIDGSTPSDNIVRRFLNICE--NTEG-AIAVHCKAGLGRTGTLI 289
              +D+  G   + L   D   P+ + + RF+ I +  N  G A+ VHC  G GRTGT++
Sbjct: 47  PPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTML 106

Query: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
           ACY++K       + IA IR  RPGSI
Sbjct: 107 ACYLVKERGLAAGDAIAEIRRLRPGSI 133


>gi|30089952 protein tyrosine phosphatase domain containing 1
           protein isoform 1 [Homo sapiens]
          Length = 806

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 232 YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENT--EGAIAVHCKAGLGRTGTLI 289
           Y  + F +AG   Y+  + D    S   +   + +      EG +A+HC AGLGRTG LI
Sbjct: 194 YLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLI 253

Query: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
           ACY++   R T  + I ++R  RP SI
Sbjct: 254 ACYLVFATRMTADQAIIFVRAKRPNSI 280


>gi|30089950 protein tyrosine phosphatase domain containing 1
           protein isoform 2 [Homo sapiens]
          Length = 754

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 232 YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENT--EGAIAVHCKAGLGRTGTLI 289
           Y  + F +AG   Y+  + D    S   +   + +      EG +A+HC AGLGRTG LI
Sbjct: 142 YLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLI 201

Query: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
           ACY++   R T  + I ++R  RP SI
Sbjct: 202 ACYLVFATRMTADQAIIFVRAKRPNSI 228


>gi|14589856 protein tyrosine phosphatase type IVA, member 3 isoform
           1 [Homo sapiens]
          Length = 173

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTE 271
           KK+  T VVR+ +  Y+       G    D  F DG+ P   +V  +L++     CE   
Sbjct: 38  KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             +AVHC AGLGR   L+A  +++     + + I +IR  R G+I   Q  +LE+
Sbjct: 98  SCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYLEK 151


>gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo
           sapiens]
          Length = 173

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 37/115 (32%), Positives = 58/115 (50%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNIC-----ENTE 271
           KK+ VT +VR+ +  Y+       G    D  F DG+ PS+ IV  +L++      E   
Sbjct: 38  KKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPG 97

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             IAVHC AGLGR   L+A  +++     + + + +IR  R G+    Q  +LE+
Sbjct: 98  CCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLYLEK 151


>gi|18104971 protein tyrosine phosphatase type IVA, member 2 isoform
           1 [Homo sapiens]
          Length = 167

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNIC-----ENTE 271
           KK+ VT +VR+    Y+       G    D  F DG+ P + IV  +LN+      E   
Sbjct: 35  KKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPG 94

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             +AVHC AGLGR   L+A  +++     + + + +IR  R G+    Q  +LE+
Sbjct: 95  CCVAVHCVAGLGRAPVLVALALIE-CGMKYEDAVQFIRQKRRGAFNSKQLLYLEK 148


>gi|169162376 PREDICTED: similar to protein tyrosine phosphatase 4a1
           isoform 1 [Homo sapiens]
          Length = 170

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLN-----ICENTE 271
           KK+  T +VR+ +  Y+       G    +  F DG+ PS+ IV  +L+      CE   
Sbjct: 35  KKYGATTIVRVCEATYDTTLVEKEGIHVLNWPFGDGAPPSNQIVADWLHFVKIKFCEEPG 94

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             IAV+C  GLG+   L+A   ++     H + + +I   R G+    Q  +LE+
Sbjct: 95  CYIAVNCIVGLGKAPVLVALASVEG-GMKHEDAVQFIGQKRSGAFKSKQLLYLEK 148


>gi|14589854 protein tyrosine phosphatase type IVA, member 3 isoform
           2 [Homo sapiens]
          Length = 148

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 5/73 (6%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTE 271
           KK+  T VVR+ +  Y+       G    D  F DG+ P   +V  +L++     CE   
Sbjct: 38  KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97

Query: 272 GAIAVHCKAGLGR 284
             +AVHC AGLGR
Sbjct: 98  SCVAVHCVAGLGR 110


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 268 ENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
           E  +G   +HC AG+ R+  L   Y+MK++  +  +   W + CRP  II P   F E+
Sbjct: 94  EMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRP--IIRPNSGFWEQ 150


>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 274 IAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFL 324
           + +HC+AG+ R+ T++  Y+MKH R T  +   +++  RP  II P  +F+
Sbjct: 62  LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 110


>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 274 IAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFL 324
           + +HC+AG+ R+ T++  Y+MKH R T  +   +++  RP  II P  +F+
Sbjct: 62  LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 110


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 274 IAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFL 324
           + +HC+AG+ R+ T++  Y+MKH R T  +   +++  RP  II P  +F+
Sbjct: 404 LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 452


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 2/83 (2%)

Query: 263 FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           F++ C    G   VHC AG+ R+ T++  YVM        +++  I+  RP  I  P   
Sbjct: 73  FIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRP--IANPNPG 130

Query: 323 FLEEKQASLWVQGDIFRSKLKNR 345
           F ++ +   W      R +L+ R
Sbjct: 131 FRQQLEEFGWASSQKLRRQLEER 153


>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 28/172 (16%)

Query: 165 DVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAV 224
           D +E+ +  R E  +   I+PG FL       KSK+             P  +KH +T +
Sbjct: 17  DAEEWTYPMRREMQE---ILPGLFLGPYSSAMKSKL-------------PVLQKHGITHI 60

Query: 225 VRLNKKIYEAKRFTDAGFEHYDLFFI--DGSTPSDNIVRRFLNICENTEGA------IAV 276
           + + + I     F    F+    + +      P +NI+R F    E  +G+      + V
Sbjct: 61  ICIRQNI--EANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLV 118

Query: 277 HCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQ 328
           H  AG+ R+   +  Y+M+ +   + +  A+++  R    I P   F+ + Q
Sbjct: 119 HGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERR--FCINPNAGFVHQLQ 168


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 28/172 (16%)

Query: 165 DVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAV 224
           D +E+ +  R E  +   I+PG FL       KSK+             P  +KH +T +
Sbjct: 17  DAEEWTYPMRREMQE---ILPGLFLGPYSSAMKSKL-------------PVLQKHGITHI 60

Query: 225 VRLNKKIYEAKRFTDAGFEHYDLFFI--DGSTPSDNIVRRFLNICENTEGA------IAV 276
           + + + I     F    F+    + +      P +NI+R F    E  +G+      + V
Sbjct: 61  ICIRQNI--EANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLV 118

Query: 277 HCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQ 328
           H  AG+ R+   +  Y+M+ +   + +  A+++  R    I P   F+ + Q
Sbjct: 119 HGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERR--FCINPNAGFVHQLQ 168


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 28/172 (16%)

Query: 165 DVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAV 224
           D +E+ +  R E  +   I+PG FL       KSK+             P  +KH +T +
Sbjct: 17  DAEEWTYPMRREMQE---ILPGLFLGPYSSAMKSKL-------------PVLQKHGITHI 60

Query: 225 VRLNKKIYEAKRFTDAGFEHYDLFFI--DGSTPSDNIVRRFLNICENTEGA------IAV 276
           + + + I     F    F+    + +      P +NI+R F    E  +G+      + V
Sbjct: 61  ICIRQNI--EANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLV 118

Query: 277 HCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQ 328
           H  AG+ R+   +  Y+M+ +   + +  A+++  R    I P   F+ + Q
Sbjct: 119 HGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERR--FCINPNAGFVHQLQ 168


>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
          Length = 403

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 21/121 (17%)

Query: 200 IENGYPLHAPEAYFPYFKKHNVTAVVRL--NKKIYEAKRFTDAGFEHYDLF--------- 248
           I  G+P    E  +    ++N+  VVR   +K     K +      HYD           
Sbjct: 33  IAMGFPAERLEGVY----RNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQY 88

Query: 249 -FIDGSTPSDNIVRRFLN-----ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHA 302
            F D + P   +++ F       + E+     A+HCKAG GRTG +I  Y++   +F  A
Sbjct: 89  PFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKA 148

Query: 303 E 303
           +
Sbjct: 149 Q 149


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 10/93 (10%)

Query: 263 FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           F+   + + G + VHC AG+ R+ T+   Y+MK    +  E   +++  RP   I P  +
Sbjct: 229 FIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRP--TISPNFN 286

Query: 323 FLEEKQASLWVQGDIFRSKLKNRPSSEGSINKI 355
           FL +           +  K+KN+  + G  +K+
Sbjct: 287 FLGQLLD--------YEKKIKNQTGASGPKSKL 311


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHF 323
           GA  VHC AG+ R+ TL   Y+MK +     E   W++  RP  +I P   F
Sbjct: 105 GATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP--VIRPNVGF 154


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 263 FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           F++  +N  G + VHC+AG+ R+ T+   Y+M+  R    E   +++  R  SII P   
Sbjct: 243 FIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRR--SIISPNFS 300

Query: 323 FL 324
           F+
Sbjct: 301 FM 302


>gi|108802609 protein tyrosine phosphatase, non-receptor type 20
           isoform 4 [Homo sapiens]
          Length = 269

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 5/56 (8%)

Query: 272 GAIAVHCKAGLGRTGT-----LIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           G + VHC AG+GRTG      ++ C ++K+  F   +I+A +R  R G +   +Q+
Sbjct: 196 GPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQY 251


>gi|108802611 protein tyrosine phosphatase, non-receptor type 20
           isoform 5 [Homo sapiens]
          Length = 228

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 5/56 (8%)

Query: 272 GAIAVHCKAGLGRTGT-----LIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           G + VHC AG+GRTG      ++ C ++K+  F   +I+A +R  R G +   +Q+
Sbjct: 155 GPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQY 210


>gi|109138573 protein tyrosine phosphatase, non-receptor type 20A
           isoform 8 [Homo sapiens]
          Length = 339

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 5/56 (8%)

Query: 272 GAIAVHCKAGLGRTGT-----LIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           G + VHC AG+GRTG      ++ C ++K+  F   +I+A +R  R G +   +Q+
Sbjct: 266 GPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQY 321


>gi|109138565 protein tyrosine phosphatase, non-receptor type 20A
           isoform 5 [Homo sapiens]
          Length = 228

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 5/56 (8%)

Query: 272 GAIAVHCKAGLGRTGT-----LIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           G + VHC AG+GRTG      ++ C ++K+  F   +I+A +R  R G +   +Q+
Sbjct: 155 GPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQY 210


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,329,070
Number of Sequences: 37866
Number of extensions: 692206
Number of successful extensions: 1365
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1179
Number of HSP's gapped (non-prelim): 180
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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