Guide to the Human Genome
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Search of human proteins with 154146189

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
         (2186 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]              4385   0.0  
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]      2187   0.0  
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]     2167   0.0  
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]              2071   0.0  
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]     1239   0.0  
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]     1219   0.0  
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]                 565   e-160
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]                545   e-154
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]                545   e-154
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]                  92   4e-18
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]                 86   5e-16
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]                  82   6e-15
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]                  80   2e-14
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]                   77   1e-13
gi|55741447 pleckstrin homology domain containing, family H (wit...    54   2e-06
gi|83716021 GRB2-associated binding protein family, member 4 [Ho...    50   2e-05
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa...    49   7e-05
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...    47   3e-04
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...    47   3e-04
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho...    46   4e-04
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    46   4e-04
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    46   4e-04
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    46   4e-04
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    44   0.002
gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo sap...    44   0.002
gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sap...    44   0.002
gi|217416392 pleckstrin homology domain containing, family H (wi...    43   0.003
gi|154354979 myosin X [Homo sapiens]                                   42   0.007
gi|24432056 hypothetical protein LOC144717 [Homo sapiens]              40   0.025
gi|126091130 Gab3 protein isoform 1 [Homo sapiens]                     40   0.033

>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
          Length = 2186

 Score = 4385 bits (11373), Expect = 0.0
 Identities = 2186/2186 (100%), Positives = 2186/2186 (100%)

Query: 1    MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEEL 60
            MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEEL
Sbjct: 1    MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEEL 60

Query: 61   EKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQW 120
            EKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQW
Sbjct: 61   EKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQW 120

Query: 121  HVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGT 180
            HVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGT
Sbjct: 121  HVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGT 180

Query: 181  GVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIF 240
            GVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIF
Sbjct: 181  GVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIF 240

Query: 241  LDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGR 300
            LDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGR
Sbjct: 241  LDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGR 300

Query: 301  RSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLF 360
            RSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLF
Sbjct: 301  RSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLF 360

Query: 361  SLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNI 420
            SLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNI
Sbjct: 361  SLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNI 420

Query: 421  EPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI 480
            EPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI
Sbjct: 421  EPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI 480

Query: 481  KGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKIL 540
            KGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKIL
Sbjct: 481  KGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKIL 540

Query: 541  KSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSD 600
            KSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSD
Sbjct: 541  KSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSD 600

Query: 601  YRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYD 660
            YRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYD
Sbjct: 601  YRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYD 660

Query: 661  STKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKP 720
            STKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKP
Sbjct: 661  STKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKP 720

Query: 721  GGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKK 780
            GGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKK
Sbjct: 721  GGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKK 780

Query: 781  EALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGK 840
            EALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGK
Sbjct: 781  EALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGK 840

Query: 841  PLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMS 900
            PLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMS
Sbjct: 841  PLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMS 900

Query: 901  FLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTRACKE 960
            FLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTRACKE
Sbjct: 901  FLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTRACKE 960

Query: 961  RTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFP 1020
            RTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFP
Sbjct: 961  RTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFP 1020

Query: 1021 ESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYI 1080
            ESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYI
Sbjct: 1021 ESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYI 1080

Query: 1081 SMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPE 1140
            SMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPE
Sbjct: 1081 SMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPE 1140

Query: 1141 YSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQ 1200
            YSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQ
Sbjct: 1141 YSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQ 1200

Query: 1201 IASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVDT 1260
            IASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVDT
Sbjct: 1201 IASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVDT 1260

Query: 1261 SFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSLI 1320
            SFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSLI
Sbjct: 1261 SFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSLI 1320

Query: 1321 GSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNFR 1380
            GSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNFR
Sbjct: 1321 GSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNFR 1380

Query: 1381 YLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQT 1440
            YLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQT
Sbjct: 1381 YLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQT 1440

Query: 1441 LPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQT 1500
            LPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQT
Sbjct: 1441 LPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQT 1500

Query: 1501 HQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAFFQGPADL 1560
            HQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAFFQGPADL
Sbjct: 1501 HQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAFFQGPADL 1560

Query: 1561 CGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIAD 1620
            CGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIAD
Sbjct: 1561 CGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIAD 1620

Query: 1621 AGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEM 1680
            AGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEM
Sbjct: 1621 AGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEM 1680

Query: 1681 LVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYW 1740
            LVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYW
Sbjct: 1681 LVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYW 1740

Query: 1741 KVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQ 1800
            KVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQ
Sbjct: 1741 KVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQ 1800

Query: 1801 DTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSY 1860
            DTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSY
Sbjct: 1801 DTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSY 1860

Query: 1861 LKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADK 1920
            LKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADK
Sbjct: 1861 LKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADK 1920

Query: 1921 FGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFE 1980
            FGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFE
Sbjct: 1921 FGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFE 1980

Query: 1981 TPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKV 2040
            TPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKV
Sbjct: 1981 TPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKV 2040

Query: 2041 SELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEI 2100
            SELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEI
Sbjct: 2041 SELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEI 2100

Query: 2101 FRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDDLSKRGV 2160
            FRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDDLSKRGV
Sbjct: 2101 FRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDDLSKRGV 2160

Query: 2161 DQTCTRVISKATPALPTVSISSSAEV 2186
            DQTCTRVISKATPALPTVSISSSAEV
Sbjct: 2161 DQTCTRVISKATPALPTVSISSSAEV 2186


>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
          Length = 2069

 Score = 2187 bits (5668), Expect = 0.0
 Identities = 1147/2177 (52%), Positives = 1532/2177 (70%), Gaps = 146/2177 (6%)

Query: 2    AGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELE 61
            A   TR+FTR+L +PG AAELR S +     +V         KP+L+EPLDYE VI + +
Sbjct: 9    ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLA------KPKLIEPLDYENVIVQKK 62

Query: 62   KTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWH 121
                ND L+++L FP DDF  A +    R + STVP  AE +A++L V E  K Y+S WH
Sbjct: 63   TQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWH 122

Query: 122  VVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTG 181
            +VNYKYE YSG+ RQLP    K +KLP H +E+D E+ DKDED  S  S KGG       
Sbjct: 123  LVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDEDAASLGSQKGG------- 174

Query: 182  VFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFL 241
            + K GWLYKGN NS ++  VT+RSFK+R+F L QL D SY +NFYKDEKISKEPKG IFL
Sbjct: 175  ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFL 232

Query: 242  DSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRR 301
            DSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI  LN+ILQ++ E  +Q +R
Sbjct: 233  DSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKR 292

Query: 302  STELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFS 361
            +        DS ++    +   E + S  ++   + AK   E E  +K+     R+ LF 
Sbjct: 293  NG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSAREAEIKLKSE---SRVKLFY 340

Query: 362  LDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIE 421
            LDPD      QK D    E  +K FEEK  KRI++ C  L+ NLQ CV ENE  P TN+E
Sbjct: 341  LDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVE 395

Query: 422  PFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI- 480
            PFFV+++L+D++ +RKISADFHVDLNH +VRQML   S AL NG+         + P + 
Sbjct: 396  PFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGS--------GQSPSVL 447

Query: 481  KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKI 539
            KG L E  +++PKQ +FSV+ PH +I LVA+IEKVL G+I   AEPY+K+ DS+K AQK+
Sbjct: 448  KGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKV 507

Query: 540  LKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVS 599
            LK+ +Q C +LG+YRMPFAWA R++FKD  GN+D+++RFS ++RQ+S+K+S +D++KL++
Sbjct: 508  LKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLA 567

Query: 600  DYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVY 659
            D+R+ ++++K+  I G+LDI +DNV  + PN V SS+IP K F   ++T  T EVEEFV 
Sbjct: 568  DFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVP 627

Query: 660  DSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGK 719
               K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIEFK+SDEE ++PLKCIYG+
Sbjct: 628  CIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGR 687

Query: 720  PGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKK 779
            PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L +F+HV+CD ++K + KK
Sbjct: 688  PGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKK 747

Query: 780  KEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGG 839
            ++ +ET VGY+WLPL+K  ++ + E +IP++ +LP  YL +Q+   G+H G +IKWVDGG
Sbjct: 748  RDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGG 807

Query: 840  KPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIM 899
            KPL K+ST +VSTV TQD H++ FFQ CQK E   +Q+  +  ++  K+L  +E  H ++
Sbjct: 808  KPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNELVKYLKSLHAMEG-HVMI 865

Query: 900  SFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTR--- 956
            +FLP ILNQLF+VL +  ++E+   VTRV+  +VA+CHEE L+  ++SY+K+ +K     
Sbjct: 866  AFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYV 925

Query: 957  ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPR 1015
            A + +TVHEEL K++T +LK S D  T   +LK+SWFFF +++KSMAQHLI+ +K++L R
Sbjct: 926  ASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLR 985

Query: 1016 PQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKM 1075
             QRFP SY + ++ +V +L  H+  K++D  E ++ ANHS+A F+KRCFTFMDRG+VFK 
Sbjct: 986  NQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQ 1045

Query: 1076 VNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHA 1135
            +NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP     +P      +  Q+L  
Sbjct: 1046 INNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-----MPFGKGRIQRYQDLQL 1100

Query: 1136 SDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREP 1195
                +YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++VLKNL+ KHSFDDRY   
Sbjct: 1101 ----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKHSFDDRYASR 1156

Query: 1196 RKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHA 1255
              QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN +    +D+             +  
Sbjct: 1157 SHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVKDESLALPAVNPLVTPQKG 1215

Query: 1256 NSVDTSFSKDVLNSIAAF------SSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDN 1309
            +++D S  KD+L +I+        S+  I++V +ADSR SL S DS  S  E++SEK+++
Sbjct: 1216 STLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNS 1275

Query: 1310 CEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFF 1369
             +K  +  +L  S +R DKLDQ+E +SLLMCFL+I+K++S + L  YW +A + E+ DFF
Sbjct: 1276 LDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFF 1335

Query: 1370 SILDVCLQNFRYLGKRNIIR--KIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHST 1427
            +I +VCL  F+Y+GKR I R   + A  + + S  N+ T                  HS 
Sbjct: 1336 TISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFN----------------HSY 1379

Query: 1428 SSHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVC 1487
               +    H+S                LL+                      ANIATEVC
Sbjct: 1380 GHSDADVLHQS----------------LLE----------------------ANIATEVC 1401

Query: 1488 LTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVC 1547
            LT LD LSLFT   + QL      N LMK+VFD Y+ F Q +QS TALK+VF +LR  + 
Sbjct: 1402 LTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIY 1461

Query: 1548 KFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSH 1607
            KFPS F++G AD+C + CYE+LKCCN +  S +TEAS LLYF MR NF++  +KS VR+H
Sbjct: 1462 KFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTH 1521

Query: 1608 LQLIKAVSQLIAD-AGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLM 1666
            LQ+I +VSQLIAD  GIGG+RFQ SL+I NN AN D+ +K+++F ++VKDLTKRIRTVLM
Sbjct: 1522 LQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLM 1581

Query: 1667 ATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHI 1726
            ATAQMKEHE DPEMLVDLQYSLA SYASTPELR+TWL+SMA+IH +NGDLSEAAMCY+H+
Sbjct: 1582 ATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHV 1641

Query: 1727 AALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPN 1786
             AL+AEYL RK   + E      LL        S+S     S G +F  G  AF  ITPN
Sbjct: 1642 TALVAEYLTRKEAVQWE----PPLLPH------SHSACLRRSRGGVFRQGCTAFRVITPN 1691

Query: 1787 IKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDF 1846
            I EE +M ED GMQD  +NE++L+E L  C + LWK+ERYELIAD+ K II ++EK+RDF
Sbjct: 1692 IDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDF 1751

Query: 1847 KKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQ--------------GFFEEEE 1892
            ++L+ LY  +HR+Y KV EV++S +RL G Y+RVAF+GQ              GFFE+E+
Sbjct: 1752 ERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDED 1811

Query: 1893 GKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYV 1952
            GKEYIYKEPKLT LSEISQRLLKLY+DKFG++NVK+IQDS KVNPKDLD KYAYIQVT+V
Sbjct: 1812 GKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHV 1871

Query: 1953 TPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYV 2012
             PFF+EKE+++RKT+FE  HNI RF+FE PFT +GK+ GGV EQCKRRTILT  H FPYV
Sbjct: 1872 IPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYV 1931

Query: 2013 KKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAG 2072
            KKRI V+ Q  T+LNPIEVAIDEMSKKV+EL QLC+  EVDMI+LQLKLQGSVSV+VNAG
Sbjct: 1932 KKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAG 1991

Query: 2073 PMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRS 2132
            P+AYARAFL++TN K+YPDN+VKLLKE+FRQF +ACGQAL VNERLIKEDQLEYQEE+++
Sbjct: 1992 PLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKA 2051

Query: 2133 HYKDMLSELSTVMNEQI 2149
            +Y++M  ELS +M+EQ+
Sbjct: 2052 NYREMAKELSEIMHEQL 2068


>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
          Length = 2068

 Score = 2167 bits (5614), Expect = 0.0
 Identities = 1131/2135 (52%), Positives = 1511/2135 (70%), Gaps = 140/2135 (6%)

Query: 44   KPRLLEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHK 103
            KP+L+EPLDYE VI + +    ND L+++L FP DDF  A +    R + STVP  AE +
Sbjct: 44   KPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEE 103

Query: 104  AENLLVKEACKFYSSQWHVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDE 163
            A++L V E  K Y+S WH+VNYKYE YSG+ RQLP    K +KLP H +E+D E+ DKDE
Sbjct: 104  AQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDE 162

Query: 164  DTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIM 223
            D  S  S KGG       + K GWLYKGN NS ++  VT+RSFK+R+F L QL D SY +
Sbjct: 163  DAASLGSQKGG-------ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNL 213

Query: 224  NFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIH 283
            NFYKDEKISKEPKG IFLDSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI 
Sbjct: 214  NFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWIT 273

Query: 284  TLNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTE 343
             LN+ILQ++ E  +Q +R+        DS ++    +   E + S  ++   + AK   E
Sbjct: 274  ILNKILQLNFEAAMQEKRNG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSARE 324

Query: 344  TEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNS 403
             E  +K+     R+ LF LDPD      QK D    E  +K FEEK  KRI++ C  L+ 
Sbjct: 325  AEIKLKSE---SRVKLFYLDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSF 376

Query: 404  NLQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALE 463
            NLQ CV ENE  P TN+EPFFV+++L+D++ +RKISADFHVDLNH +VRQML   S AL 
Sbjct: 377  NLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALM 436

Query: 464  NGNIDTITPRQSEEPHI-KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIAS 521
            NG+         + P + KG L E  +++PKQ +FSV+ PH +I LVA+IEKVL G+I  
Sbjct: 437  NGS--------GQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITH 488

Query: 522  GAEPYIKNPDSNKYAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPL 581
             AEPY+K+ DS+K AQK+LK+ +Q C +LG+YRMPFAWA R++FKD  GN+D+++RFS +
Sbjct: 489  CAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAI 548

Query: 582  FRQESSKISTEDLVKLVSDYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKP 641
            +RQ+S+K+S +D++KL++D+R+ ++++K+  I G+LDI +DNV  + PN V SS+IP K 
Sbjct: 549  YRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQ 608

Query: 642  FNMMAQTEPTVEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIE 701
            F   ++T  T EVEEFV    K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIE
Sbjct: 609  FETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIE 668

Query: 702  FKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHIL 761
            FK+SDEE ++PLKCIYG+PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L
Sbjct: 669  FKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLL 728

Query: 762  FSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQ 821
             +F+HV+CD ++K + KK++ +ET VGY+WLPL+K  ++ + E +IP++ +LP  YL +Q
Sbjct: 729  LTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQ 788

Query: 822  DSASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSN 881
            +   G+H G +IKWVDGGKPL K+ST +VSTV TQD H++ FFQ CQK E   +Q+  + 
Sbjct: 789  ELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNE 847

Query: 882  FIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQL 941
             ++  K+L  +E  H +++FLP ILNQLF+VL +  ++E+   VTRV+  +VA+CHEE L
Sbjct: 848  LVKYLKSLHAMEG-HVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGL 906

Query: 942  DHSVQSYIKFVFKTR---ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAII 997
            +  ++SY+K+ +K     A + +TVHEEL K++T +LK S D  T   +LK+SWFFF ++
Sbjct: 907  ESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVL 966

Query: 998  LKSMAQHLIDTNKIQLPRPQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVA 1057
            +KSMAQHLI+ +K++L R QRFP SY + ++ +V +L  H+  K++D  E ++ ANHS+A
Sbjct: 967  IKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLA 1026

Query: 1058 RFLKRCFTFMDRGYVFKMVNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRS 1117
             F+KRCFTFMDRG+VFK +NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP   
Sbjct: 1027 VFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP--- 1083

Query: 1118 ANIPDPLTPSESTQELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALA 1177
              +P      +  Q+L      +YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++
Sbjct: 1084 --MPFGKGRIQRYQDLQL----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1137

Query: 1178 VLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSR 1237
            VLKNL+ KHSFDDRY     QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN +    +
Sbjct: 1138 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVK 1196

Query: 1238 DDLSTNGGFQSQTAIKHANSVDTSFSKDVLNSIAAF------SSIAISTVNHADSRASLA 1291
            D+             +  +++D S  KD+L +I+        S+  I++V +ADSR SL 
Sbjct: 1197 DESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLI 1256

Query: 1292 SLDSNPSTNEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYE 1351
            S DS  S  E++SEK+++ +K  +  +L  S +R DKLDQ+E +SLLMCFL+I+K++S +
Sbjct: 1257 STDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDD 1316

Query: 1352 TLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGKRNIIR--KIAAAFKFVQSTQNNGTLKG 1409
             L  YW +A + E+ DFF+I +VCL  F+Y+GKR I R   + A  + + S  N+ T   
Sbjct: 1317 ALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFN- 1375

Query: 1410 SNPSCQTSGLLSQWMHSTSSHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNTMTSNSNE 1469
                           HS    +    H+S                LL+            
Sbjct: 1376 ---------------HSYGHSDADVLHQS----------------LLE------------ 1392

Query: 1470 IDIVHHVDTEANIATEVCLTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVN 1529
                      ANIATEVCLT LD LSLFT   + QL      N LMK+VFD Y+ F Q +
Sbjct: 1393 ----------ANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKH 1442

Query: 1530 QSATALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYF 1589
            QS TALK+VF +LR  + KFPS F++G AD+C + CYE+LKCCN +  S +TEAS LLYF
Sbjct: 1443 QSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYF 1502

Query: 1590 FMRKNFEFNKQKSIVRSHLQLIKAVSQLIAD-AGIGGSRFQHSLAITNNFANGDKQMKNS 1648
             MR NF++  +KS VR+HLQ+I +VSQLIAD  GIGG+RFQ SL+I NN AN D+ +K++
Sbjct: 1503 LMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHT 1562

Query: 1649 NFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAK 1708
            +F ++VKDLTKRIRTVLMATAQMKEHE DPEMLVDLQYSLA SYASTPELR+TWL+SMA+
Sbjct: 1563 SFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMAR 1622

Query: 1709 IHARNGDLSEAAMCYIHIAALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPS 1768
            IH +NGDLSEAAMCY+H+ AL+AEYL RK   + E      LL        S+S     S
Sbjct: 1623 IHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWE----PPLLPH------SHSACLRRS 1672

Query: 1769 GGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYEL 1828
             G +F  G  AF  ITPNI EE +M ED GMQD  +NE++L+E L  C + LWK+ERYEL
Sbjct: 1673 RGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYEL 1732

Query: 1829 IADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQ--- 1885
            IAD+ K II ++EK+RDF++L+ LY  +HR+Y KV EV++S +RL G Y+RVAF+GQ   
Sbjct: 1733 IADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQ 1792

Query: 1886 -----------GFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNK 1934
                       GFFE+E+GKEYIYKEPKLT LSEISQRLLKLY+DKFG++NVK+IQDS K
Sbjct: 1793 YQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGK 1852

Query: 1935 VNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVA 1994
            VNPKDLD KYAYIQVT+V PFF+EKE+++RKT+FE  HNI RF+FE PFT +GK+ GGV 
Sbjct: 1853 VNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVE 1912

Query: 1995 EQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDM 2054
            EQCKRRTILT  H FPYVKKRI V+ Q  T+LNPIEVAIDEMSKKV+EL QLC+  EVDM
Sbjct: 1913 EQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDM 1972

Query: 2055 IRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDV 2114
            I+LQLKLQGSVSV+VNAGP+AYARAFL++TN K+YPDN+VKLLKE+FRQF +ACGQAL V
Sbjct: 1973 IKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAV 2032

Query: 2115 NERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQI 2149
            NERLIKEDQLEYQEE++++Y++M  ELS +M+EQ+
Sbjct: 2033 NERLIKEDQLEYQEEMKANYREMAKELSEIMHEQL 2067


>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
          Length = 2073

 Score = 2071 bits (5365), Expect = 0.0
 Identities = 1087/2171 (50%), Positives = 1470/2171 (67%), Gaps = 140/2171 (6%)

Query: 7    RRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELEKTYRN 66
            R+FT+ L +PG AAELR S + A   +V        EK +++EPLDYE VI + +    +
Sbjct: 5    RKFTKRLSKPGTAAELRQSVSEAVRGSVVL------EKAKVVEPLDYENVIAQRKTQIYS 58

Query: 67   DPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWHVVNYK 126
            DPL+DLL FP +D S + +    RT+ STVPEDAE +A++L VKE  K YS+ WHVVNYK
Sbjct: 59   DPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYK 118

Query: 127  YEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSG 186
            YE +SGD R LP    +PEK+P+H FEID ED +KDED++S  S KGG       V K G
Sbjct: 119  YEDFSGDFRMLPCKSLRPEKIPNHVFEID-EDCEKDEDSSSLCSQKGG-------VIKQG 170

Query: 187  WLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTG 246
            WL+K N NST+  TVT++ FK+RYF LTQLPD SYI+N YKDEK SKE KGCI+LD+C  
Sbjct: 171  WLHKANVNSTI--TVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACID 228

Query: 247  VVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRRSTELT 306
            VVQ  ++R++AFELKM D     LAAETE +M+EW+ TL +I+QI+ +  +Q ++ T  T
Sbjct: 229  VVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVET 288

Query: 307  DLGLDSLDNSVTCECTPEETDSS-ENNLHADFAKYLTETEDTVKTTRNMERLNLFSLDPD 365
                 + D+  + +   E   +S E ++H +  KY  ETE   K +R   R NLFS D +
Sbjct: 289  -----AQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSE 343

Query: 366  IDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIEPFFV 425
            +  L       +EP+  IKPFEEK  KR ++ C  L  N+ G + +N   P TN+EPFF+
Sbjct: 344  VQRLDFSG---IEPD--IKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFI 398

Query: 426  SVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHIKGLPE 485
            ++AL+D++++ KISADFHVDLN  +VR+ML G+S  L +   D      S E +I G+ E
Sbjct: 399  NLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLAS---DGSPKGSSPESYIHGIAE 455

Query: 486  EWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKILKSNRQ 545
              L++ +Q +FSV+NPH EI LVA+IEKVL GNI   AEPYIKN D  K AQK+ ++ +Q
Sbjct: 456  SQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQ 515

Query: 546  FCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSDYRRAD 605
             CS+LG+YRMPFAWA R +FKD QG++D D RFSPL++Q+SSK+S+ED++KL+S+Y++ +
Sbjct: 516  VCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPE 575

Query: 606  RISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYDSTKYC 665
            + +K+Q IPG L+I V+ VP++  NC+TSS++P+KPF    Q   TVEVEEFV + TKYC
Sbjct: 576  K-TKLQIIPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNI-TVEVEEFVPEMTKYC 633

Query: 666  RPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLF 725
             P+ +YKN +Y+YP  LKYDSQK F KARNI VC+EF++SDE  A  LKCIYGKP G +F
Sbjct: 634  YPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVF 693

Query: 726  TSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALET 785
            T+ AY  V HH+QNP+F DE+KIELP  LH+KHH+LF+FYHV+C+IN K   KK++ +ET
Sbjct: 694  TTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVET 753

Query: 786  SVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGKPLFKV 845
             VG+AW+PL+K  +I + E  +P++ +LPP YL+  D+ S +    DIKWVDG KPL K+
Sbjct: 754  PVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKI 813

Query: 846  STFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMSFLPII 905
             + + ST+ TQD HV+ FF  CQ  +    + P    I+  K  L+  +I  ++ FLP+I
Sbjct: 814  KSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVP-GELIKYLK-CLHAMEIQVMIQFLPVI 871

Query: 906  LNQLFKVLV-QNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVF---KTRACKER 961
            L QLF+VL     ED++    T VL  IV+KCHEE LD  ++S+IK+ F   K  A + +
Sbjct: 872  LMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQ 931

Query: 962  TVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFP 1020
             +HE LA  +  +LK S D  ++  +LK+SWFFF II KSMA +L++ NKI+LPR QRFP
Sbjct: 932  LIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFP 991

Query: 1021 ESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYI 1080
            E+Y + L +L++ +  HV  +Y +  +E+R  N+S+A FLKRC T MDRG++F ++N+YI
Sbjct: 992  ETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYI 1051

Query: 1081 SMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPE 1140
            S FS  D K L +YKF+FLQ +C HEH+IPL LP+  A            Q +  S++ E
Sbjct: 1052 SGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFA--------KPKLQRVQDSNL-E 1102

Query: 1141 YSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQ 1200
            YS+++E+C+ HFL+G+LLRE   ALQ++ ++R+ A++V+KNL+ KH+FD RY+   +QA+
Sbjct: 1103 YSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAK 1162

Query: 1201 IASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVDT 1260
            IA LY+P  G+LL+N+ R+  +D         N  SRD+     GF S      AN    
Sbjct: 1163 IAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPC--GFTSP-----ANRGSL 1215

Query: 1261 SFSKDVLNSIAAFSSIAIS-TVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSL 1319
            S  KD      A+ S      +   DSR SL    +    ++       N  +  R  S 
Sbjct: 1216 STDKD-----TAYGSFQNGHGIKREDSRGSLIPEGATGFPDQ------GNTGENTRQSST 1264

Query: 1320 IGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNF 1379
              S  ++++LDQ E RSLLMC+L+I+K IS +TL+ YW +    E+ +   +L+VCL +F
Sbjct: 1265 RSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHF 1324

Query: 1380 RYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQ 1439
            RY+GKRNI R                             +   W+   S H G    +SQ
Sbjct: 1325 RYMGKRNIAR-----------------------------VHDAWL---SKHFG-IDRKSQ 1351

Query: 1440 TLPIIRGKNALSNPKL--LQMLDNTMT----SNSNEIDIVHHVDTEANIATEVCLTILDL 1493
            T+P +R ++ +   +L  L  L+++ T    S + E DI H    E N ATEV LT+LD 
Sbjct: 1352 TMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDT 1411

Query: 1494 LSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAF 1553
            +S FTQ  + QL   D  N LMK+VFD ++ F +  QS  +LKHVFASLR F+ KFPSAF
Sbjct: 1412 ISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAF 1471

Query: 1554 FQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKA 1613
            F+G  ++C +FCYEVLKCC  +  ST+ EASALLY  MR NFE+ K+K+ +R+HLQ+I A
Sbjct: 1472 FKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIA 1531

Query: 1614 VSQLIADAGI-GGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMK 1672
            VSQLIAD  + GGSRFQ SL I NNFAN D+ MK + FPAEVKDLTKRIRTVLMATAQMK
Sbjct: 1532 VSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMK 1591

Query: 1673 EHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAE 1732
            EHEKDPEML+DLQYSLA SYASTPELR+TWL+SMAKIH +NGD SEAAMCY+H+AAL+AE
Sbjct: 1592 EHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAE 1651

Query: 1733 YLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGA 1792
            +L RK                                  +F  G  AF  ITPNI EEGA
Sbjct: 1652 FLHRK---------------------------------KLFPNGCSAFKKITPNIDEEGA 1678

Query: 1793 MKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDL 1852
            MKED+GM D  Y+E +L+E L  CV+ LWK+ERYE+I++++K I+ ++EK+R+F+KL+ +
Sbjct: 1679 MKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQV 1738

Query: 1853 YYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQR 1912
            Y  +H +Y K+ EV++++KRL G ++RVAFYGQ FFEEE+GKEYIYKEPKLTGLSEIS R
Sbjct: 1739 YRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLR 1798

Query: 1913 LLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHH 1972
            L+KLY +KFG +NVKIIQDS+KVN K+LDPKYA+IQVTYV P+F++KE+ +RKT+FE +H
Sbjct: 1799 LVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNH 1858

Query: 1973 NINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVA 2032
            NI+RFVFE P+TLSGKK G + EQCKRRTILTTS+ FPYVKKRI +  +    L PI+VA
Sbjct: 1859 NISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVA 1918

Query: 2033 IDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDN 2092
             DE+  K +EL +LC+  +VDMI+LQLKLQG VSV+VNAGP+AYARAFL ++ A KYP  
Sbjct: 1919 TDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPK 1978

Query: 2093 QVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGR 2152
            +V  LK++FR+F  AC  AL++NERLIKEDQ+EY E L+S+++DM+ ELS +++EQI   
Sbjct: 1979 KVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQE 2038

Query: 2153 DDLSKRGVDQT 2163
            D +    +  T
Sbjct: 2039 DTMHSPWMSNT 2049


>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
          Length = 1254

 Score = 1239 bits (3207), Expect = 0.0
 Identities = 638/1284 (49%), Positives = 893/1284 (69%), Gaps = 59/1284 (4%)

Query: 2    AGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELE 61
            A   TR+FTR+L +PG AAELR S +     +V         KP+L+EPLDYE VI + +
Sbjct: 9    ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLA------KPKLIEPLDYENVIVQKK 62

Query: 62   KTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWH 121
                ND L+++L FP DDF  A +    R + STVP  AE +A++L V E  K Y+S WH
Sbjct: 63   TQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWH 122

Query: 122  VVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTG 181
            +VNYKYE YSG+ RQLP    K +KLP H +E+D E+ DKDED  S  S KGG       
Sbjct: 123  LVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDEDAASLGSQKGG------- 174

Query: 182  VFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFL 241
            + K GWLYKGN NS ++  VT+RSFK+R+F L QL D SY +NFYKDEKISKEPKG IFL
Sbjct: 175  ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFL 232

Query: 242  DSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRR 301
            DSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI  LN+ILQ++ E  +Q +R
Sbjct: 233  DSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKR 292

Query: 302  STELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFS 361
            +        DS ++    +   E + S  ++   + AK   E E  +K+     R+ LF 
Sbjct: 293  NG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSAREAEIKLKSE---SRVKLFY 340

Query: 362  LDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIE 421
            LDPD      QK D    E  +K FEEK  KRI++ C  L+ NLQ CV ENE  P TN+E
Sbjct: 341  LDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVE 395

Query: 422  PFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI- 480
            PFFV+++L+D++ +RKISADFHVDLNH +VRQML   S AL NG+         + P + 
Sbjct: 396  PFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGS--------GQSPSVL 447

Query: 481  KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKI 539
            KG L E  +++PKQ +FSV+ PH +I LVA+IEKVL G+I   AEPY+K+ DS+K AQK+
Sbjct: 448  KGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKV 507

Query: 540  LKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVS 599
            LK+ +Q C +LG+YRMPFAWA R++FKD  GN+D+++RFS ++RQ+S+K+S +D++KL++
Sbjct: 508  LKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLA 567

Query: 600  DYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVY 659
            D+R+ ++++K+  I G+LDI +DNV  + PN V SS+IP K F   ++T  T EVEEFV 
Sbjct: 568  DFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVP 627

Query: 660  DSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGK 719
               K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIEFK+SDEE ++PLKCIYG+
Sbjct: 628  CIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGR 687

Query: 720  PGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKK 779
            PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L +F+HV+CD ++K + KK
Sbjct: 688  PGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKK 747

Query: 780  KEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGG 839
            ++ +ET VGY+WLPL+K  ++ + E +IP++ +LP  YL +Q+   G+H G +IKWVDGG
Sbjct: 748  RDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGG 807

Query: 840  KPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIM 899
            KPL K+ST +VSTV TQD H++ FFQ CQK E   +Q+  +  ++  K+L  +E  H ++
Sbjct: 808  KPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNELVKYLKSLHAMEG-HVMI 865

Query: 900  SFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTR--- 956
            +FLP ILNQLF+VL +  ++E+   VTRV+  +VA+CHEE L+  ++SY+K+ +K     
Sbjct: 866  AFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYV 925

Query: 957  ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPR 1015
            A + +TVHEEL K++T +LK S D  T   +LK+SWFFF +++KSMAQHLI+ +K++L R
Sbjct: 926  ASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLR 985

Query: 1016 PQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKM 1075
             QRFP SY + ++ +V +L  H+  K++D  E ++ ANHS+A F+KRCFTFMDRG+VFK 
Sbjct: 986  NQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQ 1045

Query: 1076 VNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHA 1135
            +NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP     +P      +  Q+L  
Sbjct: 1046 INNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-----MPFGKGRIQRYQDLQL 1100

Query: 1136 SDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREP 1195
                +YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++VLKNL+ KHSFDDRY   
Sbjct: 1101 ----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKHSFDDRYASR 1156

Query: 1196 RKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHA 1255
              QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN +    +D+             +  
Sbjct: 1157 SHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVKDESLALPAVNPLVTPQKG 1215

Query: 1256 NSVDTSFSKDVLNSIAAFSSIAIS 1279
            +++D S  KD+L +I+   +   S
Sbjct: 1216 STLDNSLHKDLLGAISGIGNAPCS 1239


>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
          Length = 1253

 Score = 1219 bits (3153), Expect = 0.0
 Identities = 622/1242 (50%), Positives = 872/1242 (70%), Gaps = 53/1242 (4%)

Query: 44   KPRLLEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHK 103
            KP+L+EPLDYE VI + +    ND L+++L FP DDF  A +    R + STVP  AE +
Sbjct: 44   KPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEE 103

Query: 104  AENLLVKEACKFYSSQWHVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDE 163
            A++L V E  K Y+S WH+VNYKYE YSG+ RQLP    K +KLP H +E+D E+ DKDE
Sbjct: 104  AQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDE 162

Query: 164  DTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIM 223
            D  S  S KGG       + K GWLYKGN NS ++  VT+RSFK+R+F L QL D SY +
Sbjct: 163  DAASLGSQKGG-------ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNL 213

Query: 224  NFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIH 283
            NFYKDEKISKEPKG IFLDSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI 
Sbjct: 214  NFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWIT 273

Query: 284  TLNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTE 343
             LN+ILQ++ E  +Q +R+        DS ++    +   E + S  ++   + AK   E
Sbjct: 274  ILNKILQLNFEAAMQEKRNG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSARE 324

Query: 344  TEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNS 403
             E  +K+     R+ LF LDPD      QK D    E  +K FEEK  KRI++ C  L+ 
Sbjct: 325  AEIKLKSE---SRVKLFYLDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSF 376

Query: 404  NLQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALE 463
            NLQ CV ENE  P TN+EPFFV+++L+D++ +RKISADFHVDLNH +VRQML   S AL 
Sbjct: 377  NLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALM 436

Query: 464  NGNIDTITPRQSEEPHI-KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIAS 521
            NG+         + P + KG L E  +++PKQ +FSV+ PH +I LVA+IEKVL G+I  
Sbjct: 437  NGS--------GQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITH 488

Query: 522  GAEPYIKNPDSNKYAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPL 581
             AEPY+K+ DS+K AQK+LK+ +Q C +LG+YRMPFAWA R++FKD  GN+D+++RFS +
Sbjct: 489  CAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAI 548

Query: 582  FRQESSKISTEDLVKLVSDYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKP 641
            +RQ+S+K+S +D++KL++D+R+ ++++K+  I G+LDI +DNV  + PN V SS+IP K 
Sbjct: 549  YRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQ 608

Query: 642  FNMMAQTEPTVEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIE 701
            F   ++T  T EVEEFV    K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIE
Sbjct: 609  FETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIE 668

Query: 702  FKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHIL 761
            FK+SDEE ++PLKCIYG+PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L
Sbjct: 669  FKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLL 728

Query: 762  FSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQ 821
             +F+HV+CD ++K + KK++ +ET VGY+WLPL+K  ++ + E +IP++ +LP  YL +Q
Sbjct: 729  LTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQ 788

Query: 822  DSASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSN 881
            +   G+H G +IKWVDGGKPL K+ST +VSTV TQD H++ FFQ CQK E   +Q+  + 
Sbjct: 789  ELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNE 847

Query: 882  FIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQL 941
             ++  K+L  +E  H +++FLP ILNQLF+VL +  ++E+   VTRV+  +VA+CHEE L
Sbjct: 848  LVKYLKSLHAMEG-HVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGL 906

Query: 942  DHSVQSYIKFVFKTR---ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAII 997
            +  ++SY+K+ +K     A + +TVHEEL K++T +LK S D  T   +LK+SWFFF ++
Sbjct: 907  ESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVL 966

Query: 998  LKSMAQHLIDTNKIQLPRPQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVA 1057
            +KSMAQHLI+ +K++L R QRFP SY + ++ +V +L  H+  K++D  E ++ ANHS+A
Sbjct: 967  IKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLA 1026

Query: 1058 RFLKRCFTFMDRGYVFKMVNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRS 1117
             F+KRCFTFMDRG+VFK +NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP   
Sbjct: 1027 VFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP--- 1083

Query: 1118 ANIPDPLTPSESTQELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALA 1177
              +P      +  Q+L      +YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++
Sbjct: 1084 --MPFGKGRIQRYQDLQL----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1137

Query: 1178 VLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSR 1237
            VLKNL+ KHSFDDRY     QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN +    +
Sbjct: 1138 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVK 1196

Query: 1238 DDLSTNGGFQSQTAIKHANSVDTSFSKDVLNSIAAFSSIAIS 1279
            D+             +  +++D S  KD+L +I+   +   S
Sbjct: 1197 DESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCS 1238


>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
          Length = 2109

 Score =  565 bits (1455), Expect = e-160
 Identities = 386/1274 (30%), Positives = 614/1274 (48%), Gaps = 138/1274 (10%)

Query: 942  DHSVQSYIKFVFKTRACKERTVHEELA---KNVTGLLKSN--------------DSTTVK 984
            D  V+S I      R+C   + H E +   + +TG L +                 +  +
Sbjct: 912  DDEVRSIIGSKAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRE 971

Query: 985  HVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFPESYQNELDNLVMVLSDHVIWKYKD 1044
              L+ +WFFF +++KSM  HL   +K++ PR  RFPE + +++  LV  ++  ++ +++ 
Sbjct: 972  SALQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPERFMDDIAALVSTIASDIVSRFQK 1031

Query: 1045 ALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYISMFSSG-----DLKTLCQYKFDFL 1099
              E   R N S+A FL    + MDRG+VF ++ +     SS      +   L   + DFL
Sbjct: 1032 DTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSSKLYSLPNPSVLVSLRLDFL 1091

Query: 1100 QEVCQHEHFIPLCLPIRSANIPDPLTPSEST------------QELHASDMPEYSVTNEF 1147
            + +C HEH++ L LP      P   +PS S+            Q+   ++M E SV   F
Sbjct: 1092 RIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVP--F 1149

Query: 1148 CRKHFLIGILLREVGFALQEDQD----VRHLALAVLKNLMAKHSFDDRYREPRKQAQIAS 1203
             ++H+L G++L E+   L  D +    +    + ++ NL++ H  D RY +P+ +A++A 
Sbjct: 1150 RQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAM 1209

Query: 1204 LYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVDTSFS 1263
            LY+PL G++++ +P+     LY FT  T NQ  R        ++S++             
Sbjct: 1210 LYLPLIGIIMETVPQ-----LYDFT-ETHNQRGRPICIATDDYESESG------------ 1251

Query: 1264 KDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSLIGST 1323
                       S+   TV  A +  S+  L                    P    L  ++
Sbjct: 1252 -----------SMISQTVAMAIAGTSVPQLTR------------------PGSFLLTSTS 1282

Query: 1324 LRFDKLDQAET-RSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNFRYL 1382
             R      AE+ RSLL+C L ++K      L  ++      +++    +L +C+  F Y 
Sbjct: 1283 GRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYK 1342

Query: 1383 GKRNIIRKIAAAFKFVQSTQNN--GTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQT 1440
            GK+   R  +  FK  +  +      + GS  + Q     S+    T +     +     
Sbjct: 1343 GKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLGTYTIASPPERSPSG 1402

Query: 1441 LPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQT 1500
                  +N      +     NT   + +  +I H    + N+ATE  L ILD L +  QT
Sbjct: 1403 SAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQT 1462

Query: 1501 HQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAFFQGPADL 1560
                +   + + S++  V    +     NQSA  L+H FA+ R  V KFP   F+   + 
Sbjct: 1463 ----VSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQ 1518

Query: 1561 CGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIAD 1620
            C   C  +L+ C+    + ++ ASA LY  MR+NFE     +  R  +Q+  ++S L+  
Sbjct: 1519 CADLCLRLLRHCSSSIGTIRSHASASLYLLMRQNFEIGN--NFARVKMQVTMSLSSLVGT 1576

Query: 1621 AGIGGSRF-QHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPE 1679
            +      F + SL     +A  D +++ + FP +V+DL   +  +L  T +MKEH++DPE
Sbjct: 1577 SQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPE 1636

Query: 1680 MLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGY 1739
            ML+DL Y +A  Y ++P+LR TWL++MA  H+   + +EAA C +H AAL+AEYL     
Sbjct: 1637 MLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYL----- 1691

Query: 1740 WKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGAMKEDSGM 1799
                     S+L +  +                  +G   F +I+ N+ EE A+ +D   
Sbjct: 1692 ---------SMLEDRKY----------------LPVGCVTFQNISSNVLEESAVSDDVVS 1726

Query: 1800 QDTP-------YNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDL 1852
             D         + E+ LV  L         +  YE + +V K +I + E  RD KKLS +
Sbjct: 1727 PDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTI 1786

Query: 1853 YYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQR 1912
            +  +  ++ K+       +R+FG Y+RV FYG  F + +E +E++YKEP +T L+EIS R
Sbjct: 1787 HGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDE-QEFVYKEPAITKLAEISHR 1845

Query: 1913 LLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHH 1972
            L   Y ++FG D V++I+DSN V+   LDP  AYIQ+TYV P+F+  E++DR T F+ ++
Sbjct: 1846 LEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNY 1905

Query: 1973 NINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVA 2032
            N+ RF++ TPFTL G+ HG + EQ KR+TILTTSH FPY+K R+ V  +    L PIEVA
Sbjct: 1906 NLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVA 1965

Query: 2033 IDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDN 2092
            I++M KK  EL      +  D   LQ+ LQGSV   VN GP+  A+ FL E  +      
Sbjct: 1966 IEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFR 2025

Query: 2093 QVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGR 2152
                L+  F+ F   C  AL  N+ LI  DQ EYQ EL  +Y  +   L  ++N +I   
Sbjct: 2026 HHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKI--- 2082

Query: 2153 DDLSKRGVDQTCTR 2166
              L K  +  TC R
Sbjct: 2083 PQLYKAVLPVTCHR 2096



 Score =  260 bits (664), Expect = 1e-68
 Identities = 190/692 (27%), Positives = 333/692 (48%), Gaps = 139/692 (20%)

Query: 343 ETEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALN 402
           + +D  K+ R+ E   LF+L P  D     +++ +E  SV    +E   +R+++ C +L 
Sbjct: 222 QNDDQRKSNRHKE---LFALHPSPD-----EEEPIERLSVPDIPKEHFGQRLLVKCLSLK 273

Query: 403 SNLQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVAL 462
             ++             IEP F S+ALYD+++ +KIS +F+ DLN   ++ +L       
Sbjct: 274 FEIE-------------IEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLL------- 313

Query: 463 ENGNIDTITPRQSEEPHIKGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLM-GNIAS 521
                          PH+   P       + A+FS++ P  ++ LV K+EKVL  G+I  
Sbjct: 314 --------------RPHVP--PAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGE 357

Query: 522 GAEPYI--KNPDSNKYAQKI--LKSNR-QFCSKLGKYRMPFAWAVRSVFK--DNQGNVDR 574
            AEPY+  K  D+ K  +K+  LKS   QFC +LGKYRMPFAW    +     + G+++R
Sbjct: 358 CAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLER 417

Query: 575 DSR-----------------------------------------FSP-------LFRQES 586
           DS                                          F P        F+QE 
Sbjct: 418 DSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTNFFKQEG 477

Query: 587 SKISTEDLVKLVSDYRRADRI-SKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMM 645
            ++S EDL K ++D RR   +  +++ I   L I +   P     C+T   + VK +   
Sbjct: 478 DRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPELLQVKLYPD- 536

Query: 646 AQTEPTVEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNS 705
           ++  PT E+ EF   +     P   Y+N +YIYP+ L + +++    ARNITV ++F   
Sbjct: 537 SRVRPTREILEF--PARDVYVPNTTYRNLLYIYPQSLNFANRQ--GSARNITVKVQFMYG 592

Query: 706 DEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFY 765
           ++ S   +  I+GK     F+  AYTAV++H+++PDF +E+K++LP  L + HH+LF+FY
Sbjct: 593 EDPS-NAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFY 651

Query: 766 HVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSAS 825
           HV+C        K+   LET VGY W+P++++ ++ + ++ +P++   PP   S      
Sbjct: 652 HVSC------QQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEV 705

Query: 826 GKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDM----------S 875
              G   +KWVD  K +F V    VS+++TQDP+++ FF      ++ +           
Sbjct: 706 PLPG---MKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHLFPVRIGDMRIM 762

Query: 876 QSPTSNFIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLV-------------QNEEDEIT 922
           ++   N ++S  + LN  ++  ++ FL ++L++L  +++             Q   + + 
Sbjct: 763 ENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQASFEAMA 822

Query: 923 TTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFK 954
           + + R+  ++     +   +  + SYI +VF+
Sbjct: 823 SIINRLHKNLEGNHDQHGRNSLLASYIHYVFR 854



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 5/110 (4%)

Query: 48  LEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENL 107
           ++P+D E  +        + PL+DL+ FP DD        D RTL S VPE++E      
Sbjct: 55  VDPVDLEDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPH-- 112

Query: 108 LVKEACKFYSSQWHVVNYKYEQYSGDI--RQLPRAEYKPEKLPSHSFEID 155
            V++  + Y+  W +V  KY +         L + + + + LP   FE D
Sbjct: 113 -VRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESD 161


>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
          Length = 2099

 Score =  545 bits (1405), Expect = e-154
 Identities = 374/1227 (30%), Positives = 614/1227 (50%), Gaps = 147/1227 (11%)

Query: 956  RACKERTVHEELAKNV---TGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQ 1012
            R   ++  HEELA  +   TG+++         V K++WFFF +++KSMAQH+ + +K  
Sbjct: 953  RPASKKHFHEELALQMVVSTGMVRET-------VFKYAWFFFELLVKSMAQHVHNMDKRD 1005

Query: 1013 LPRPQRFPESYQNELDNLVMVLSDHV---IWKYKDALEETRRANHSVARFLKRCFTFMDR 1069
              R  RF + + +++  +V V++  +   + K +   E+  + N S+A FL    + MDR
Sbjct: 1006 SFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDR 1065

Query: 1070 GYVFKMVNNYISMFSS--GDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPS 1127
            G+VF ++ +Y S  S+   +L TL   + +FL+ +C HEH++ L L   +A+   P +P 
Sbjct: 1066 GFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTA-PTSPC 1124

Query: 1128 ESTQELHASDMPEYS---------VTNEFCRKHFLIGILLREVGFALQEDQD----VRHL 1174
             S    ++S    +          +T+E+ ++HFL G+L  E+  AL  + +    V+  
Sbjct: 1125 PSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRK 1184

Query: 1175 ALAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQ 1234
            A++ + +L++ H  D R  +P  + +IA+LY+PL G++LD +P+     L  FTV  + +
Sbjct: 1185 AVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQ-----LCDFTVADTRR 1239

Query: 1235 GSRDDLSTNGGFQSQTAIKHANSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASLASLD 1294
                   T+G  + Q      N       ++V  +IA          N+ + + S   L 
Sbjct: 1240 -----YRTSGSDEEQEGAGAIN-------QNVALAIAG---------NNFNLKTSGIVLS 1278

Query: 1295 SNPSTNEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLI 1354
            S P                           +++ L+   TR+L++CFL IMK      + 
Sbjct: 1279 SLPYK-------------------------QYNMLNADTTRNLMICFLWIMKNADQSLIR 1313

Query: 1355 AYWQRAPSPEVSDFFSILDVCLQNFRYLGKRN---IIRKIAAAFKFVQSTQNNGTLKGSN 1411
             +    PS +++    +L +C+  F Y GK++   +  ++    + V++      L+G  
Sbjct: 1314 KWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGE- 1372

Query: 1412 PSCQTSGLLSQWMHSTSSHEGHKQHRSQTLPIIRGKNALSNPKLL-QMLDNTMTSNSNEI 1470
                  G   + M   +         ++ L   R K   ++ +   + LD T      E 
Sbjct: 1373 ------GARGEMMRRRAPGNDRFPGLNENL---RWKKEQTHWRQANEKLDKTKAELDQEA 1423

Query: 1471 DIVHHVDTEANIATEVCLTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQ 1530
             I        N+ATE  L ILD+     Q         DC++SL+  V    +     +Q
Sbjct: 1424 LI------SGNLATEAHLIILDMQENIIQASSA----LDCKDSLLGGVLRVLVNSLNCDQ 1473

Query: 1531 SATALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFF 1590
            S T L H FA+LR  + KF    F+   + C   C++VL  C+     T+++A A LY  
Sbjct: 1474 STTYLTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLL 1533

Query: 1591 MRKNFEFNKQKSIVRSHLQLIKAVSQLIADA-GIGGSRFQHSLAITNNFANGDKQMKNSN 1649
            MR  F F    +  R  +Q+  +++ L+  A        + SL     ++  D  M+ + 
Sbjct: 1534 MR--FSFGATSNFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTP 1591

Query: 1650 FPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKI 1709
            FP +V++L   + ++L  T +M+E ++DPEML+DL Y +A SY ++P+LR TWL++MA+ 
Sbjct: 1592 FPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEK 1651

Query: 1710 HARNGDLSEAAMCYIHIAALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSG 1769
            H +    +EAAMC +H AAL+AEYL              S+L + ++             
Sbjct: 1652 HTKKKCYTEAAMCLVHAAALVAEYL--------------SMLEDHSY------------- 1684

Query: 1770 GSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTP-------YNENILVEQLYMCVEFLWK 1822
                 +G  +F +I+ N+ EE  + ED+   D         + E+ LV  L    E    
Sbjct: 1685 ---LPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFST 1741

Query: 1823 SERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAF 1882
               YE + +V K +I + E  R+F+KL+  +  + R++  +  V    KR+FG Y+RV F
Sbjct: 1742 GGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSI--VNKDHKRMFGTYFRVGF 1799

Query: 1883 YGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDP 1942
            +G  F + +E +E++YKEP +T L EIS RL   Y   FGA+ V++I+DS  V+   LDP
Sbjct: 1800 FGSKFGDLDE-QEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDP 1858

Query: 1943 KYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTI 2002
              AYIQ+T+V P+F+E E++DR T FE + N+ RF++ TPFTL G+  G + EQ +R T+
Sbjct: 1859 NKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTV 1918

Query: 2003 LTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQ 2062
            LTT H FPY+K RI VI +    L PIEVAI++M KK  +L      E  D   LQ+ LQ
Sbjct: 1919 LTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQ 1978

Query: 2063 GSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKED 2122
            GSV   VN GP+  A+ FL E  A          L+  F++F   CG+A++ N+RLI  D
Sbjct: 1979 GSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITAD 2038

Query: 2123 QLEYQEELRSHYKDMLSELSTVMNEQI 2149
            Q EYQ+EL+ +Y  +   L  ++  +I
Sbjct: 2039 QREYQQELKKNYNKLKENLRPMIERKI 2065



 Score =  285 bits (730), Expect = 3e-76
 Identities = 214/696 (30%), Positives = 338/696 (48%), Gaps = 137/696 (19%)

Query: 285 LNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTET 344
           LN +  +S +GP+         D  L SL      E   ++  +       DF K   + 
Sbjct: 182 LNVLCDVSGKGPVTA------CDFDLRSLQPDKRLENLLQQVSAE------DFEK---QN 226

Query: 345 EDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSN 404
           E+  +T R  E   LF+L P +D     ++D +E   V +  +E    RI++    L   
Sbjct: 227 EEARRTNRQAE---LFALYPSVD-----EEDAVEIRPVPECPKEHLGNRILVKLLTLKFE 278

Query: 405 LQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALEN 464
           ++             IEP F S+ALYD+++ +KIS +FH DLN    +  L         
Sbjct: 279 IE-------------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFL--------- 316

Query: 465 GNIDTITPRQSEEPHIKGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLM-GNIASGA 523
                    ++  P +    +      + AVFSV+ P S+I LV KIEKVL  G I   A
Sbjct: 317 ---------RAHTPSVAASSQA-----RSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCA 362

Query: 524 EPY--IKNPDSNKYAQKILKSNRQ---FCSKLGKYRMPFAWAVRSVFKD-NQGNVDRD-- 575
           EPY  IK  D  K  +KI K   Q   FC +LGKYRMPFAWA  S+    N   ++R+  
Sbjct: 363 EPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVT 422

Query: 576 ------------------------------------SRF-------SPLFRQESSKISTE 592
                                               S F       S  F+QE  ++S E
Sbjct: 423 DVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDE 482

Query: 593 DLVKLVSDYRRADRISK-MQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPT 651
           DL K ++DY+R+  + + +++IPG L + +   P     C+T   +PVKPF    +T P 
Sbjct: 483 DLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPEN-RTRPH 541

Query: 652 VEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAK 711
            E+ EF   + +   P+ VY+N +Y+YP+ L + ++     ARNIT+ I+F    E+++ 
Sbjct: 542 KEILEF--PTREVYVPHTVYRNLLYVYPQRLNFVNKLA--SARNITIKIQFM-CGEDASN 596

Query: 712 PLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDI 771
            +  I+GK  GP F    YTAV +H+++PDF +EVKI+LP +L   HH+LF+FYH++C  
Sbjct: 597 AMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISC-- 654

Query: 772 NAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIA-TSLPPNYLSFQDSASGKHGG 830
                 K+  ++ET +GY+WLP++ ++++ +  Y +P+A   LPPNY S   +       
Sbjct: 655 ----QQKQGASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNY-SMHSAEKVPLQN 709

Query: 831 SDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKRE-----------KDMSQSPT 879
             IKW +G K +F +    VS+V+TQD H+  FF  C   E           + +S+   
Sbjct: 710 PPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMAL 769

Query: 880 SNFIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQ 915
            + ++     LN  ++  ++ FL ++L++LF++ VQ
Sbjct: 770 EHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQ 805



 Score = 32.7 bits (73), Expect = 4.0
 Identities = 26/109 (23%), Positives = 50/109 (45%), Gaps = 6/109 (5%)

Query: 48  LEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENL 107
           +EP+D+E ++     +      Q+L  F  DD        + RTL  ++PE+      + 
Sbjct: 59  VEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPH- 117

Query: 108 LVKEACKFYSSQWHVVNYKYE---QYSGDIRQLPRAEYKPEKLPSHSFE 153
            V++  + Y  +W +VN K +   +  G  +   R ++  + LP  +FE
Sbjct: 118 -VRDCVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFH-KTLPKQTFE 164


>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
          Length = 2047

 Score =  545 bits (1403), Expect = e-154
 Identities = 370/1223 (30%), Positives = 586/1223 (47%), Gaps = 128/1223 (10%)

Query: 955  TRACKERTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLP 1014
            +R    + +HEELA         + S   + +L+H+WFFF +++KSMA HL+   ++  P
Sbjct: 900  SRILASKLLHEELALQWV----VSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTP 955

Query: 1015 RPQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFK 1074
            R  RFP  + +++  LV  +   VI +    +E     N S+A FL    + +DRG+VF 
Sbjct: 956  RKLRFPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFS 1015

Query: 1075 MVNNYISMF-----SSGDLKTLCQYKFDFLQEVCQHEHFIPL---CLPIRSANIPDPLTP 1126
            +V  +         SS +   L   + +F + +C HEH++ L   C P+     P P   
Sbjct: 1016 LVRAHYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVS 1075

Query: 1127 SESTQE-LHASDMPEYSVTN------EFCRKHFLIGILLREVGFALQEDQDVRHL----A 1175
            S ++Q    +S  P+  VT+       F ++HFL G+LL E+  AL+ + +   L    A
Sbjct: 1076 STTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKA 1135

Query: 1176 LAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQG 1235
            ++ + +L+  H  D RY E   +A++A LY+PL  +  D +PR++               
Sbjct: 1136 ISAVHSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLH--------------- 1180

Query: 1236 SRDDLSTNGGFQSQTAIKHANSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASLASLDS 1295
               D +   G +S+ A    +  DT    D+  +I    S+A++      +  S AS+  
Sbjct: 1181 ---DFAEGPGQRSRLASMLDS--DTEGEGDIAGTINP--SVAMAIAGGPLAPGSRASISQ 1233

Query: 1296 NPSTNEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIA 1355
             P T  ++      C                  L    +R+LL C L ++K      L  
Sbjct: 1234 GPPTASRAG-----CA-----------------LSAESSRTLLACVLWVLKNTEPALLQR 1271

Query: 1356 YWQRAPSPEVSDFFSILDVCLQNFRYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQ 1415
            +      P++     +L +CL  F Y GK+   R  +  FK                S  
Sbjct: 1272 WATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFK---------------KSLD 1316

Query: 1416 TSGLLSQWMHSTSSHEGHKQHRS-QTLPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVH 1474
                L + +  T         RS +  P    +N      +      +   +  + ++ H
Sbjct: 1317 MKARLEEAILGTIGARQEMVRRSRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEH 1376

Query: 1475 HVDTEANIATEVCLTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATA 1534
                E N+ATE  L +LD L +  QT    +   + + S++  V    +      QSA  
Sbjct: 1377 EALVEGNLATEASLVVLDTLEIIVQT----VMLSEARESVLGAVLKVVLYSLGSAQSALF 1432

Query: 1535 LKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKN 1594
            L+H  A+ R  V KFP   F+   +LC   C  +L+ C  R  + +T ASA LY  MR+N
Sbjct: 1433 LQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQN 1492

Query: 1595 FEFNKQKSIVRSHLQLIKAVSQLIADA-GIGGSRFQHSLAITNNFANGDKQMKNSNFPAE 1653
            FE     +  R  +Q+  ++S L+           + SL     +A  D  +++S F  +
Sbjct: 1493 FEIGH--NFARVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQ 1550

Query: 1654 VKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARN 1713
            V+DL   +  +L  T +MKEH++DPEML+DL Y +A  Y  +P+LR TWL++MA  HA  
Sbjct: 1551 VQDLMFNLHMILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAEL 1610

Query: 1714 GDLSEAAMCYIHIAALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMF 1773
            G+ +EAA C +H AAL+AEYL              +LL +  H                 
Sbjct: 1611 GNHAEAAQCMVHAAALVAEYL--------------ALLEDHRH----------------L 1640

Query: 1774 SMGWPAFLSITPNIKEEGAMKEDSGMQDTP-------YNENILVEQLYMCVEFLWKSERY 1826
             +G  +F +I+ N+ EE A+ +D    D         + E  LV  L     +      Y
Sbjct: 1641 PVGCVSFQNISSNVLEESAISDDILSPDEEGFCSGKHFTELGLVGLLEQAAGYFTMGGLY 1700

Query: 1827 ELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQG 1886
            E + +V K +I + E  RD+KKL+ ++  +  ++ K+    +  +R+FG Y+RV FYG  
Sbjct: 1701 EAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGAH 1760

Query: 1887 FFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAY 1946
            F + +E +E++YKEP +T L+EIS RL + Y ++FG D V+II+DSN V+   LD + AY
Sbjct: 1761 FGDLDE-QEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDSQKAY 1819

Query: 1947 IQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTILTTS 2006
            IQ+TYV P+F+  E++DR T F+ ++ +  F+F TPFT  G+ HG + EQ KR+T+L+T 
Sbjct: 1820 IQITYVEPYFDTYELKDRVTYFDRNYGLRTFLFCTPFTPDGRAHGELPEQHKRKTLLSTD 1879

Query: 2007 HLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVS 2066
            H FPY+K RI+V  +  T L P+EVAI++M KK  EL      +  D   LQ+ LQGSV 
Sbjct: 1880 HAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVG 1939

Query: 2067 VKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEY 2126
              VN GP+  A+ FL E             L+  F+ F   C  AL  N+ LI  DQ EY
Sbjct: 1940 PTVNQGPLEVAQVFLAEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEY 1999

Query: 2127 QEELRSHYKDMLSELSTVMNEQI 2149
              EL  +Y  +   L  ++ +++
Sbjct: 2000 HRELERNYCRLREALQPLLTQRL 2022



 Score =  236 bits (603), Expect = 1e-61
 Identities = 186/670 (27%), Positives = 315/670 (47%), Gaps = 116/670 (17%)

Query: 311 DSLDNSVTCECTPEETDSSE----NNLHAD-FAKYLTETEDTVKTTRNMERLNLFSLDPD 365
           DS   S + E TP  + +S      NL AD     L E        R  E L      P 
Sbjct: 171 DSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPA 230

Query: 366 IDTL--KLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIEPF 423
           + TL     + + +E  S  +P  E   +RI++ C +L   ++             IEP 
Sbjct: 231 LLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIE-------------IEPI 277

Query: 424 FVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHIKGL 483
           F  +ALYD+R+ +KIS +F+ DLN  +++ +L                      P I  L
Sbjct: 278 FGILALYDVREKKKISENFYFDLNSDSMKGLLRA----------------HGTHPAISTL 321

Query: 484 PEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLM-GNIASGAEPY--IKNPDSNKYAQKIL 540
                   + A+FSV+ P  +I LV K+EKVL  G+I+   EPY  +K  D+ K  +K+ 
Sbjct: 322 A-------RSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLE 374

Query: 541 K---SNRQFCSKLGKYRMPFAWAVRSVFK--DNQGNVDRDSR------------------ 577
           K   +  QFC++LG+YRMPFAW    +     + G +DRDS                   
Sbjct: 375 KLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQ 434

Query: 578 --------------FSP-------LFRQESSKISTEDLVKLVSDYRR-ADRISKMQTIPG 615
                         F P        F+QE+ ++S EDL K ++D RR +  + +++ +  
Sbjct: 435 DRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTA 494

Query: 616 SLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYDSTKYCRPYRVYKNQI 675
            L I +   P     C++   + +KP+    +  PT E+ EF   + +   P+  Y+N +
Sbjct: 495 QLKIDISPAPENPHFCLSPELLHIKPYPD-PRGRPTKEILEF--PAREVYAPHTSYRNLL 551

Query: 676 YIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLH 735
           Y+YP  L + S++     RN+ V +++   ++ S + L  I+GK     FT  A+T V++
Sbjct: 552 YVYPHSLNFSSRQ--GSVRNLAVRVQYMTGEDPS-QALPVIFGKSSCSEFTREAFTPVVY 608

Query: 736 HSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAWLPLM 795
           H+++P+F +E K+ LP  + E HH+LF+FYHV+C        +   ALET VG+ W+PL+
Sbjct: 609 HNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSC------QPRPGTALETPVGFTWIPLL 662

Query: 796 KHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNT 855
           +H ++ +  + +P++   PP   S         G   ++WVDG K +F V    VS+V+ 
Sbjct: 663 QHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPG---MRWVDGHKGVFSVELTAVSSVHP 719

Query: 856 QDPHVNAFFQECQKREKD----------MSQSPTSNFIRSCKNLLNVEKIHAIMSFLPII 905
           QDP+++ FF      E+           +S+      +R+    L +     +++F   +
Sbjct: 720 QDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHV 779

Query: 906 LNQLFKVLVQ 915
           L++L +++++
Sbjct: 780 LDKLVRLVIR 789



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 45/185 (24%), Positives = 75/185 (40%), Gaps = 8/185 (4%)

Query: 1   MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQ---EKPRLLEPLDYETVI 57
           MA    R F   + R   A   +  +   +    SSR+           ++EPLD+E V+
Sbjct: 1   MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVL 60

Query: 58  EELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYS 117
                     PL+DL+ FP+DD        + RT    +P+D +  A+   V+ A + Y 
Sbjct: 61  LSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQ---VRAAVEMYI 117

Query: 118 SQWHVVNYKYEQYSGDIRQLPRAEYKPEK--LPSHSFEIDHEDADKDEDTTSHSSSKGGG 175
             W +V+ +Y+  S     +     +  +  LP   FE D    ++     S+ S +G G
Sbjct: 118 EDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDSRRGSG 177

Query: 176 GAGGT 180
               T
Sbjct: 178 SPEDT 182


>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
          Length = 2030

 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 85/376 (22%), Positives = 153/376 (40%), Gaps = 30/376 (7%)

Query: 1817 VEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGR 1876
            + +  K + +E    + + +   +E   D++ LS     I +      + +  ++RL   
Sbjct: 1298 IHYFNKGKSWEFGIPLCRELACQYESLYDYQSLSW----IRKMEASYYDNIMEQQRLEPE 1353

Query: 1877 YYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVN 1936
            ++RV FYG+ F      KEY+ +      L    QR+L  +           +Q  N  +
Sbjct: 1354 FFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVA------MQHPNHPD 1407

Query: 1937 PKDLDPKYAYIQVTYVTPF------FEEKEIEDRKTDFEMHHNINRFVFETPFTLSGK-K 1989
               L     Y+Q+  VTP        +   + DR   F   +N+ +F ++ PF    K K
Sbjct: 1408 DAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDK 1467

Query: 1990 HGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTM 2049
                      RT LT +H  P + +  +V  +   E++P+E AI  +  K  EL  L + 
Sbjct: 1468 ENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRSLISQ 1527

Query: 2050 EEVDMIR-----LQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKL--LKEIFR 2102
             +   +      L + L G +   VN G   Y  AF ++    K+P +  K+  LKE+ +
Sbjct: 1528 YQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYINKHPGDAEKITQLKELMQ 1587

Query: 2103 QFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDDLSK--RGV 2160
            +     G  L V+E+ +  +     ++L   ++ M + L      +  G D LS    G 
Sbjct: 1588 EQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASL----YHEFPGLDKLSPACSGT 1643

Query: 2161 DQTCTRVISKATPALP 2176
                  V++  +P  P
Sbjct: 1644 STPRGNVLASHSPMSP 1659



 Score = 36.2 bits (82), Expect = 0.36
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 12/105 (11%)

Query: 694 RNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQ 753
           +NI V +    +D E  K   CI    G P   S+ ++ VL+HS +P + + +K+ +P  
Sbjct: 442 KNIEVTMYVLYADGEILKD--CISLGSGEPN-RSSYHSFVLYHSNSPRWGEIIKLPIPID 498

Query: 754 LHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHD 798
                H+ F F H  C    K   K         G+A+  LM+ D
Sbjct: 499 RFRGSHLRFEFRH--CSTKDKGEKK-------LFGFAFSTLMRDD 534


>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
          Length = 1870

 Score = 85.5 bits (210), Expect = 5e-16
 Identities = 87/393 (22%), Positives = 173/393 (44%), Gaps = 18/393 (4%)

Query: 1804 YNENILVEQLYM-CVEFLWKSERYELIADVNKPIIAVFE-KQRDFKKLSDLYYDIHRSYL 1861
            Y +  L E+LY   + +  K + +E    ++K +   +E K  D++ L +L       Y 
Sbjct: 1291 YTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFYE 1350

Query: 1862 KVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKF 1921
             + + +  +      Y+ V +YGQGF      K +IY+  +     + S RLL  + +  
Sbjct: 1351 NIIKAMRPQPE----YFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQFPNAE 1406

Query: 1922 GADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFET 1981
               +     +  K +PK     +    V  + P +++K + ++  ++   + + +F +  
Sbjct: 1407 KMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRANEVQQFRYSR 1466

Query: 1982 PFTLSGKKHGG-VAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEM---S 2037
            PF    K      A     RT  TT++ FP + K  +V   S+ E++P+E AI+ M   +
Sbjct: 1467 PFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETMELTN 1526

Query: 2038 KKVSE-LNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQ--V 2094
            +++S  + Q      + +  L + L G V   V  G   Y +AF  E   +++P++Q  V
Sbjct: 1527 ERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTEKYLQEHPEDQEKV 1586

Query: 2095 KLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDD 2154
            +LLK +         + + ++   + E      E L S ++++  ++       IT   +
Sbjct: 1587 ELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKVEKHYG-VITLPPN 1645

Query: 2155 LSKRGVDQTCTRVI----SKATPALPTVSISSS 2183
            L++R   +T + V+    S     L   S++SS
Sbjct: 1646 LTERKQSRTGSIVLPYIMSSTLRRLSITSVTSS 1678



 Score = 41.2 bits (95), Expect = 0.011
 Identities = 56/267 (20%), Positives = 114/267 (42%), Gaps = 40/267 (14%)

Query: 672 KNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYT 731
           +N IY+   H ++D  K     +N+ V +     DEE     K I+  PG      + Y 
Sbjct: 443 RNDIYVTLIHGEFDKGKK-KTPKNVEVTMSVH--DEEGKLLEKAIH--PGAGYEGISEYK 497

Query: 732 AVLHHS-QNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYA 790
           +V+++  + P + + VK+ +  +   + HI F+F H       +++ + ++  E + G A
Sbjct: 498 SVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVA 550

Query: 791 WLPLM----------KHDQIASQEYN-----IPIATSLPPNYLSFQDS--ASGKHGGSDI 833
           ++ LM          +HD +  +  N          +LP   +  ++    + K+  +  
Sbjct: 551 FVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFT 610

Query: 834 KWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVE 893
              D  K  F+++T + ST  TQ+  +               +S + N   + K L+ V+
Sbjct: 611 PSKDSTKDSFQIATLICSTKLTQNVDLLGLLN---------WRSNSQNIKHNLKKLMEVD 661

Query: 894 KIHAIMSFLPIILNQLFKVLVQNEEDE 920
               I+ FL   L+ LF ++++  + E
Sbjct: 662 G-GEIVKFLQDTLDALFNIMMEMSDSE 687


>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
          Length = 1830

 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 74/347 (21%), Positives = 145/347 (41%), Gaps = 13/347 (3%)

Query: 1800 QDTPYNENILVEQLY-MCVEFLWKSERYELIADVNKPIIAVFEKQR-DFKKLSDLYYDIH 1857
            Q  P     L E LY   + +  K + +E    + K +   +E +  D++ LS       
Sbjct: 1267 QQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQA 1326

Query: 1858 RSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLY 1917
            + Y  + +++  +      Y+ V +YGQGF      K +IY+  +     +   +L+  +
Sbjct: 1327 KFYESIMKILRPKPD----YFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQF 1382

Query: 1918 ADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRF 1977
             +    +      D  K  P      +    V    P F+ K + D+  +F   + + RF
Sbjct: 1383 PNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRF 1442

Query: 1978 VFETPFTLSG-KKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEM 2036
             +  P            A     RT   T++  P + +  +V+  S T ++P+E AI+ M
Sbjct: 1443 HYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETM 1502

Query: 2037 S----KKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDN 2092
            S    K +  +NQ  + E + +  L + L G V   V  G   Y +AF  E   + +P++
Sbjct: 1503 STANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPED 1562

Query: 2093 QVKL--LKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDM 2137
            Q KL  LK++        G  + ++E+ + ++   + + +   +K++
Sbjct: 1563 QDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNL 1609



 Score = 35.8 bits (81), Expect = 0.47
 Identities = 58/297 (19%), Positives = 116/297 (39%), Gaps = 53/297 (17%)

Query: 672 KNQIYIYPKHLKYDSQKCFNKA--RNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAA 729
           +N IYI      +D    +NK   RN+ V +     D ++     C+ G    P+     
Sbjct: 423 RNDIYITLLQGDFDK---YNKTTQRNVEVIMCVCAEDGKTLPNAICV-GAGDKPM---NE 475

Query: 730 YTAVLHHS-QNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVG 788
           Y +V+++  + P + + VK+ +P +  ++ H+ F F H       +++ + K+  E +  
Sbjct: 476 YRSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFA 528

Query: 789 YAWLPLMKHD---------------------QIASQEYNIPIATSLPPNYLSFQDSASGK 827
            +++ LMK D                     + AS    +P       N  +    +S  
Sbjct: 529 MSYVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSS 588

Query: 828 HGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCK 887
            GG  +      + +F +ST V ST  TQ+  +    +   K +           ++   
Sbjct: 589 VGGLSV----SSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQ----------LLQENL 634

Query: 888 NLLNVEKIHAIMSFLPIILNQLFKVLVQ-NEEDEITTTVTRVLTDIVAKCHEEQLDH 943
             L +     ++ FL   L+ LF ++++ ++ DE    V   L  I+    + +  H
Sbjct: 635 EKLKIVDGEEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQH 691


>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
          Length = 1966

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 76/322 (23%), Positives = 139/322 (43%), Gaps = 25/322 (7%)

Query: 1834 KPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEG 1893
            + I   +E   D++ LS +       Y K+ +    ++RL   ++RV FYG+ F      
Sbjct: 1277 RKIAEQYESYYDYRNLSKMRMMEASLYDKIMD----QQRLEPEFFRVGFYGKKFPFFLRN 1332

Query: 1894 KEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVT 1953
            KE++ +      L    QR+L  +           +Q +N+ +      +  Y+Q+  VT
Sbjct: 1333 KEFVCRGHDYERLEAFQQRMLNEFPHAIA------MQHANQPDETIFQAEAQYLQIYAVT 1386

Query: 1954 PFFEEKEIEDR-------KTDFEMHHNINRFVFETPFTLSGK-KHGGVAEQCKRRTILTT 2005
            P  E +E+  R       K+ ++++H I +F ++ PF    K K          RT L  
Sbjct: 1387 PIPESQEVLQREGVPDNIKSFYKVNH-IWKFRYDRPFHKGTKDKENEFKSLWVERTSLYL 1445

Query: 2006 SHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQL---CTMEEVDMIR-LQLKL 2061
                P + +  +V  +   E++P+E AI+ +  K  +L  L   C   ++  I  L + L
Sbjct: 1446 VQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNINPLTMCL 1505

Query: 2062 QGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKL--LKEIFRQFADACGQALDVNERLI 2119
             G +   VN G   Y  AF  +     +P++  K+  L+E+  + A      L V+E+ +
Sbjct: 1506 NGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKFV 1565

Query: 2120 KEDQLEYQEELRSHYKDMLSEL 2141
             +D     ++L   +  M S L
Sbjct: 1566 PQDMRPLHKKLVDQFFVMKSSL 1587



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 70/319 (21%), Positives = 130/319 (40%), Gaps = 35/319 (10%)

Query: 693  ARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPT 752
            ARN+ V +   +S   S + LK       G    S  ++ VL+H+ +P +S+ +K+ +P 
Sbjct: 421  ARNVEVTMFIVDS---SGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477

Query: 753  QLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATS 812
                  HI F F H  C    K   K         G++++PLM+ D     +    +   
Sbjct: 478  DKFRGAHIRFEFRH--CSTKEKGEKK-------LFGFSFVPLMQEDGRTLPDGTHELIVH 528

Query: 813  LPPNYLSFQDS--------ASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFF 864
                  + QD+        + G   G++ + +   K  F +++F+ ST  TQ+  +    
Sbjct: 529  KCEENTNLQDTTRYLKLPFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLL 588

Query: 865  QECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQNEEDEITTT 924
            +     +K          I  C + L       I+ FL   L+ LF +L +N + +  + 
Sbjct: 589  KWRTHPDK----------ITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDENSQ-KYGSK 637

Query: 925  VTRVLTDIVAKCHEEQLDH---SVQSYIKFVFKTRACKERTVHEELAKNVTGLLKSNDST 981
            V   L  I+    + +  H    + +YI+  F   A   R + + L   V  + ++    
Sbjct: 638  VFDSLVHIINLLQDSKFHHFKPVMDTYIESHF-AGALAYRDLIKVLKWYVDRITEAERQE 696

Query: 982  TVKHVLKHSWFFFAIILKS 1000
             ++ VLK   + F  I++S
Sbjct: 697  HIQEVLKAQEYIFKYIVQS 715


>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
          Length = 1865

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 85/410 (20%), Positives = 168/410 (40%), Gaps = 31/410 (7%)

Query: 1793 MKEDSGMQDTPYNENILVEQLYM-CVEFLWKSERYELIADVNKPIIAVFEKQR-DFKKLS 1850
            + +  G Q T   +  L EQLY   + +  K + +E    + K +   +E +  D+++LS
Sbjct: 1258 LTQRDGYQATTQGQ--LKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLS 1315

Query: 1851 DLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEIS 1910
            +L     + Y  + +V+  +      Y+ V +YGQGF     GK +IY+  +     +  
Sbjct: 1316 ELLKKQAQFYENIVKVIRPKPD----YFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFE 1371

Query: 1911 QRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFE-----EKEIEDRK 1965
             RLL  + +           D  K +P        YIQ   V P  +      + + ++ 
Sbjct: 1372 ARLLTQFPNAEKMKTTSPPGDDIKNSPGQ------YIQCFTVKPKLDLPPKFHRPVSEQI 1425

Query: 1966 TDFEMHHNINRFVFETPFTLSGKKHGG-VAEQCKRRTILTTSHLFPYVKKRIQVISQSST 2024
              F   + + RF +  P     K      A     RTI TT++  P + +  +V S    
Sbjct: 1426 VSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMV 1485

Query: 2025 ELNPIEVAIDEMSKKVSELNQLCTME----EVDMIRLQLKLQGSVSVKVNAGPMAYARAF 2080
            E++P+E AI+ M     ++N +         + +  L + L G V   V  G   Y +AF
Sbjct: 1486 EISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAF 1545

Query: 2081 LEETNAKKYPD--NQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDML 2138
              +   +++P+   +++ LK++         + + ++   + E    + E + + +K + 
Sbjct: 1546 FTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLK 1605

Query: 2139 SELS-----TVMNEQITGRDDLSKRGVDQTCTRVISKATPALPTVSISSS 2183
             ++       +M   +  R     R + ++ T   S    ++ +VS  SS
Sbjct: 1606 EKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSS 1655



 Score = 48.1 bits (113), Expect = 9e-05
 Identities = 76/351 (21%), Positives = 146/351 (41%), Gaps = 45/351 (12%)

Query: 672  KNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYT 731
            +N IY+      +D       A+N+ V +   + D    K L+ +     G    S   +
Sbjct: 425  RNDIYVTLVQGDFDKGSK-TTAKNVEVTVSVYDED---GKRLEHVIFPGAGDEAISEYKS 480

Query: 732  AVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAW 791
             + +  + P + + VK+ +P +   + H+ F+F H       +++   K+  E     A+
Sbjct: 481  VIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRH-------RSSQDSKDKSEKIFALAF 533

Query: 792  LPLMKHD--QIASQEYNIPI-----------AT--SLPPNYLSFQD---SASGKHGGSDI 833
            + LM++D   +   E+++ +           AT  SLP      ++   SA+GK   S +
Sbjct: 534  VKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQS-L 592

Query: 834  KWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVE 893
                  K  F++ST V ST  TQ+  +    +          +S TS   ++ + L+ V+
Sbjct: 593  GSCTISKDSFQISTLVCSTKLTQNVDLLGLLK---------WRSNTSLLQQNLRQLMKVD 643

Query: 894  KIHAIMSFLPIILNQLFKVLVQNEEDE-ITTTVTRVLTDIVAKCHEEQLDH---SVQSYI 949
                ++ FL   L+ LF ++++N E E   T V   L  I+    + +  H    +++YI
Sbjct: 644  G-GEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYI 702

Query: 950  KFVFKTRACKERTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKS 1000
            K  F       + + + L   V G  K   +  +   +K     F  I++S
Sbjct: 703  KKHFSATLAYTK-LTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRS 752


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 42/146 (28%), Positives = 72/146 (49%), Gaps = 16/146 (10%)

Query: 151 SFEIDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRY 210
           S + D+ + +     TS S S  G G GG  + KSG+L K            V+++K+R+
Sbjct: 549 SLDSDYSEPEHKLQRTS-SYSTDGLGLGGESLEKSGYLLKMGSQ--------VKTWKRRW 599

Query: 211 FQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVL 270
           F L Q      IM +     + ++P+G + L+S   +V+    +   F+L     TY+ L
Sbjct: 600 FVLRQ----GQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQ--TFQLISEKKTYY-L 652

Query: 271 AAETESDMDEWIHTLNRILQISPEGP 296
            A++ S ++EWI  L  +L++   GP
Sbjct: 653 TADSPSLLEEWIRVLQSLLKVQATGP 678


>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
           sapiens]
          Length = 574

 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 41/134 (30%), Positives = 70/134 (52%), Gaps = 20/134 (14%)

Query: 169 SSSKGGGGAGGTG----VFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLT--QLPDNSYI 222
           SS  G G AGG+     V  SGWL K    S     + + +++KR+F L   Q   +  +
Sbjct: 23  SSWPGSGPAGGSTRSGHVLYSGWLRK----SPPEKKLRLFAWRKRWFILRRGQTSSDPDV 78

Query: 223 MNFYKDEKISKEPKGCIFLDSCTGVVQNNRL--------RKYAFELKMNDLTYFVLAAET 274
           + +YK++  SK+P   I L+ C  +  +  L        + Y F++K ++ T++ L AET
Sbjct: 79  LEYYKNDG-SKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFY-LVAET 136

Query: 275 ESDMDEWIHTLNRI 288
             DM+EW+ ++ +I
Sbjct: 137 REDMNEWVQSICQI 150


>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
           sapiens]
          Length = 676

 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 48/169 (28%), Positives = 80/169 (47%), Gaps = 30/169 (17%)

Query: 177 AGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLT--QLPDNSYIMNFYKDEKISKE 234
           +GG  V  +GWL K    S     +   ++KKR+F L   ++  +  ++ +YK++  SK+
Sbjct: 2   SGGGDVVCTGWLRK----SPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDH-SKK 56

Query: 235 PKGCIFLDSCTGVVQNNRLRK------YAFELKMNDLTYFVLAAETESDMDEWIHTLNRI 288
           P   I L+ C  V       K      + F++K ++ T++ L AETE DM++W+ ++ +I
Sbjct: 57  PLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFY-LVAETEEDMNKWVQSICQI 115

Query: 289 LQISPEGPLQGRRSTELTDLGLDSLDNSVTC----ECTPEETDSSENNL 333
                 G  Q   ST       DSL N  +       +P E  SS  +L
Sbjct: 116 C-----GFNQAEEST-------DSLRNVSSAGHGPRSSPAELSSSSQHL 152


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
           sapiens]
          Length = 645

 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 26/116 (22%)

Query: 184 KSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDS 243
           K GWL K            V+++++RYF L      +  + +YKDE+ +K P+GC++L  
Sbjct: 49  KMGWLKK--------QRSIVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPG 94

Query: 244 CT--GVVQN-NRLRKYAFEL--------KMNDLTYFVLAAETESDMDEWIHTLNRI 288
           CT   +  N     K+ FE+        +M   +Y VL A ++++M+EW+  L R+
Sbjct: 95  CTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSY-VLMASSQAEMEEWVKFLRRV 149


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
           sapiens]
          Length = 638

 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 26/116 (22%)

Query: 184 KSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDS 243
           K GWL K            V+++++RYF L      +  + +YKDE+ +K P+GC++L  
Sbjct: 42  KMGWLKK--------QRSIVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPG 87

Query: 244 CT--GVVQN-NRLRKYAFEL--------KMNDLTYFVLAAETESDMDEWIHTLNRI 288
           CT   +  N     K+ FE+        +M   +Y VL A ++++M+EW+  L R+
Sbjct: 88  CTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSY-VLMASSQAEMEEWVKFLRRV 142


>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
            sapiens]
          Length = 638

 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 58/273 (21%), Positives = 116/273 (42%), Gaps = 38/273 (13%)

Query: 1794 KEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLY 1853
            KED   ++  +NEN+  E   +  +F+ + +  E +      I ++ ++++      +L 
Sbjct: 214  KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEK------ELS 267

Query: 1854 YDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRL 1913
              +H+      E +  EK LF               EEE K+ + +  KL    E ++RL
Sbjct: 268  SSLHQKLCSFQEEMVKEKNLF---------------EEELKQTLDELDKLQQKEEQAERL 312

Query: 1914 LKLYAD--KFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEK------EIEDRK 1965
            +K   +  K  A+ +K++++  K+  K+ + + +    T  T   +EK       +ED  
Sbjct: 313  VKQLEEEAKSRAEELKLLEE--KLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVT 370

Query: 1966 TDFEMHHNINRFVFE------TPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVI 2019
              FE +  +     E      +       K G  AE  + + + T S    YV+  + + 
Sbjct: 371  AQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQ 430

Query: 2020 SQSSTELNPIEVAIDEMSKKVSEL-NQLCTMEE 2051
            ++S+ +   I+       +K+++L NQL   EE
Sbjct: 431  TKSALKETEIKEITVSFLQKITDLQNQLKQQEE 463


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
            sapiens]
          Length = 725

 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 58/273 (21%), Positives = 116/273 (42%), Gaps = 38/273 (13%)

Query: 1794 KEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLY 1853
            KED   ++  +NEN+  E   +  +F+ + +  E +      I ++ ++++      +L 
Sbjct: 301  KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEK------ELS 354

Query: 1854 YDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRL 1913
              +H+      E +  EK LF               EEE K+ + +  KL    E ++RL
Sbjct: 355  SSLHQKLCSFQEEMVKEKNLF---------------EEELKQTLDELDKLQQKEEQAERL 399

Query: 1914 LKLYAD--KFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEK------EIEDRK 1965
            +K   +  K  A+ +K++++  K+  K+ + + +    T  T   +EK       +ED  
Sbjct: 400  VKQLEEEAKSRAEELKLLEE--KLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVT 457

Query: 1966 TDFEMHHNINRFVFE------TPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVI 2019
              FE +  +     E      +       K G  AE  + + + T S    YV+  + + 
Sbjct: 458  AQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQ 517

Query: 2020 SQSSTELNPIEVAIDEMSKKVSEL-NQLCTMEE 2051
            ++S+ +   I+       +K+++L NQL   EE
Sbjct: 518  TKSALKETEIKEITVSFLQKITDLQNQLKQQEE 550


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
            sapiens]
          Length = 709

 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 58/273 (21%), Positives = 116/273 (42%), Gaps = 38/273 (13%)

Query: 1794 KEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLY 1853
            KED   ++  +NEN+  E   +  +F+ + +  E +      I ++ ++++      +L 
Sbjct: 285  KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEK------ELS 338

Query: 1854 YDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRL 1913
              +H+      E +  EK LF               EEE K+ + +  KL    E ++RL
Sbjct: 339  SSLHQKLCSFQEEMVKEKNLF---------------EEELKQTLDELDKLQQKEEQAERL 383

Query: 1914 LKLYAD--KFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEK------EIEDRK 1965
            +K   +  K  A+ +K++++  K+  K+ + + +    T  T   +EK       +ED  
Sbjct: 384  VKQLEEEAKSRAEELKLLEE--KLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVT 441

Query: 1966 TDFEMHHNINRFVFE------TPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVI 2019
              FE +  +     E      +       K G  AE  + + + T S    YV+  + + 
Sbjct: 442  AQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQ 501

Query: 2020 SQSSTELNPIEVAIDEMSKKVSEL-NQLCTMEE 2051
            ++S+ +   I+       +K+++L NQL   EE
Sbjct: 502  TKSALKETEIKEITVSFLQKITDLQNQLKQQEE 534


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
            sapiens]
          Length = 724

 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 58/273 (21%), Positives = 116/273 (42%), Gaps = 38/273 (13%)

Query: 1794 KEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLY 1853
            KED   ++  +NEN+  E   +  +F+ + +  E +      I ++ ++++      +L 
Sbjct: 300  KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEK------ELS 353

Query: 1854 YDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRL 1913
              +H+      E +  EK LF               EEE K+ + +  KL    E ++RL
Sbjct: 354  SSLHQKLCSFQEEMVKEKNLF---------------EEELKQTLDELDKLQQKEEQAERL 398

Query: 1914 LKLYAD--KFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEK------EIEDRK 1965
            +K   +  K  A+ +K++++  K+  K+ + + +    T  T   +EK       +ED  
Sbjct: 399  VKQLEEEAKSRAEELKLLEE--KLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVT 456

Query: 1966 TDFEMHHNINRFVFE------TPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVI 2019
              FE +  +     E      +       K G  AE  + + + T S    YV+  + + 
Sbjct: 457  AQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQ 516

Query: 2020 SQSSTELNPIEVAIDEMSKKVSEL-NQLCTMEE 2051
            ++S+ +   I+       +K+++L NQL   EE
Sbjct: 517  TKSALKETEIKEITVSFLQKITDLQNQLKQQEE 549


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 17/147 (11%)

Query: 183  FKSGWLY----KGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISK--EPK 236
            FK GW+      G   S    T +   +KK +F LT   D+S  + +Y+D    +  E  
Sbjct: 1780 FKKGWMSILDEPGEPPSPSLTTTSTSQWKKHWFVLT---DSS--LKYYRDSTAEEADELD 1834

Query: 237  GCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGP 296
            G I L SCT V +    R Y F++   D  Y  L+A T      WI  L + ++     P
Sbjct: 1835 GEIDLRSCTDVTEYAVQRNYGFQIHTKDAVY-TLSAMTSGIRRNWIEALRKTVR-----P 1888

Query: 297  LQGRRSTELTDLGLDSLDNSVTCECTP 323
                  T+L+D   ++  +S + +  P
Sbjct: 1889 TSAPDVTKLSDSNKENALHSYSTQKGP 1915


>gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 17/147 (11%)

Query: 183 FKSGWLY----KGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISK--EPK 236
           FK GW+      G   S    T +   +KK +F LT   D+S  + +Y+D    +  E  
Sbjct: 67  FKKGWMSILDEPGEPPSPSLTTTSTSQWKKHWFVLT---DSS--LKYYRDSTAEEADELD 121

Query: 237 GCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGP 296
           G I L SCT V +    R Y F++   D  Y  L+A T      WI  L + ++     P
Sbjct: 122 GEIDLRSCTDVTEYAVQRNYGFQIHTKDAVY-TLSAMTSGIRRNWIEALRKTVR-----P 175

Query: 297 LQGRRSTELTDLGLDSLDNSVTCECTP 323
                 T+L+D   ++  +S + +  P
Sbjct: 176 TSAPDVTKLSDSNKENALHSYSTQKGP 202


>gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo
           sapiens]
          Length = 652

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 17/147 (11%)

Query: 183 FKSGWLY----KGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISK--EPK 236
           FK GW+      G   S    T +   +KK +F LT   D+S  + +Y+D    +  E  
Sbjct: 67  FKKGWMSILDEPGEPPSPSLTTTSTSQWKKHWFVLT---DSS--LKYYRDSTAEEADELD 121

Query: 237 GCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGP 296
           G I L SCT V +    R Y F++   D  Y  L+A T      WI  L + ++     P
Sbjct: 122 GEIDLRSCTDVTEYAVQRNYGFQIHTKDAVY-TLSAMTSGIRRNWIEALRKTVR-----P 175

Query: 297 LQGRRSTELTDLGLDSLDNSVTCECTP 323
                 T+L+D   ++  +S + +  P
Sbjct: 176 TSAPDVTKLSDSNKENALHSYSTQKGP 202


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 43.1 bits (100), Expect = 0.003
 Identities = 37/164 (22%), Positives = 74/164 (45%), Gaps = 16/164 (9%)

Query: 147 LPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSF 206
           +P  ++  D E +  ++      SS    G     + KSG+L K +          V+S+
Sbjct: 670 IPPDAYSTDTEYSQPEQKLPKTCSSSSDNGKNEP-LEKSGYLLKMSGK--------VKSW 720

Query: 207 KKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLT 266
           K+R+F L        ++ +     + ++P+G I L +   +++ +   K   +L     T
Sbjct: 721 KRRWFVLK----GGELLYYKSPSDVIRKPQGHIELSASCSILRGDN--KQTVQLTTEKHT 774

Query: 267 YFVLAAETESDMDEWIHTLNRILQISPEGPLQGRRSTELTDLGL 310
           Y+ L A++ + ++EWI  L  +L++    PL  +   + T  GL
Sbjct: 775 YY-LTADSPNILEEWIKVLQNVLRVQAANPLSLQPEGKPTMKGL 817


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 42.0 bits (97), Expect = 0.007
 Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 11/105 (10%)

Query: 184  KSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDS 243
            K GWL+K    S+   T++ R++KKR+F L Q    S +M F  D +  ++ KG + + +
Sbjct: 1215 KQGWLHKKGGGSS---TLSRRNWKKRWFVLRQ----SKLMYFENDSE--EKLKGTVEVRT 1265

Query: 244  CTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRI 288
               ++ +N  ++   ++ M D T F L AE+  D  +W   L+++
Sbjct: 1266 AKEII-DNTTKENGIDIIMADRT-FHLIAESPEDASQWFSVLSQV 1308


>gi|24432056 hypothetical protein LOC144717 [Homo sapiens]
          Length = 249

 Score = 40.0 bits (92), Expect = 0.025
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)

Query: 223 MNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKM--NDLTYFVLAAETESDMDE 280
           M FY ++  S+EP G I L+ CT V       ++AF ++        +VLAAE++  M+ 
Sbjct: 45  MLFYFEDAASREPVGVIILEGCT-VELVEAAEEFAFAVRFAGTRARTYVLAAESQDAMEG 103

Query: 281 WIHTLNR 287
           W+  L+R
Sbjct: 104 WVKALSR 110


>gi|126091130 Gab3 protein isoform 1 [Homo sapiens]
          Length = 587

 Score = 39.7 bits (91), Expect = 0.033
 Identities = 28/116 (24%), Positives = 56/116 (48%), Gaps = 15/116 (12%)

Query: 185 SGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQ--LPDNSYIMNFYKDEKISKEPKGCIFLD 242
           +GWL K    S     +   +++KR+F L +  +  N  ++ +Y+++  SK P   I L 
Sbjct: 9   TGWLVK----SPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSSK-PIRVIDLS 63

Query: 243 SCT-------GVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQI 291
            C          V+      + F +K    T++ L A+TE +M  W+H+++++  +
Sbjct: 64  ECAVWKHVGPSFVRKEFQNNFVFIVKTTSRTFY-LVAKTEQEMQVWVHSISQVCNL 118


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,876,915
Number of Sequences: 37866
Number of extensions: 3461383
Number of successful extensions: 10830
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 10435
Number of HSP's gapped (non-prelim): 327
length of query: 2186
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2068
effective length of database: 13,779,330
effective search space: 28495654440
effective search space used: 28495654440
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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