Guide to the Human Genome
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Search of human proteins with 153945707

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153945707 endothelin converting enzyme 2 isoform C [Homo
sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153945707 endothelin converting enzyme 2 isoform C [Homo sapi...   527   e-150
gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi...   332   1e-91
gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]                   122   4e-28
gi|55956895 CGI-01 protein isoform 3 [Homo sapiens]                   109   3e-24
gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]                    67   2e-11
gi|112734863 methyltransferase like 12 [Homo sapiens]                  62   5e-10
gi|58219056 methyltransferase like 10 [Homo sapiens]                   47   2e-05
gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]     32   0.41 
gi|15553097 hypothetical protein MGC9084 [Homo sapiens]                31   1.2  
gi|4505697 pendrin [Homo sapiens]                                      30   2.0  
gi|31340735 zinc finger protein 445 [Homo sapiens]                     30   2.7  
gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform...    29   3.5  
gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform ...    29   3.5  
gi|37588873 ring finger protein 128 isoform 1 [Homo sapiens]           29   4.6  
gi|89145417 methyltransferase like 7A [Homo sapiens]                   28   5.9  
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]          28   7.8  
gi|153251913 hypothetical protein LOC57604 isoform 1 [Homo sapiens]    28   7.8  

>gi|153945707 endothelin converting enzyme 2 isoform C [Homo
           sapiens]
          Length = 255

 Score =  527 bits (1358), Expect = e-150
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60
           MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED
Sbjct: 1   MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60

Query: 61  RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120
           RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP
Sbjct: 61  RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120

Query: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPH 180
           SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPH
Sbjct: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPH 180

Query: 181 FRTRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKLSVAQLALGAQILSPPRPPTSPCF 240
           FRTRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKLSVAQLALGAQILSPPRPPTSPCF
Sbjct: 181 FRTRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKLSVAQLALGAQILSPPRPPTSPCF 240

Query: 241 LQDSDHEDFLSAIQL 255
           LQDSDHEDFLSAIQL
Sbjct: 241 LQDSDHEDFLSAIQL 255


>gi|153945761 endothelin converting enzyme 2 isoform A [Homo
           sapiens]
          Length = 883

 Score =  332 bits (852), Expect = 1e-91
 Identities = 161/161 (100%), Positives = 161/161 (100%)

Query: 1   MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60
           MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED
Sbjct: 1   MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60

Query: 61  RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120
           RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP
Sbjct: 61  RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120

Query: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEV 161
           SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEV
Sbjct: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEV 161


>gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]
          Length = 699

 Score =  122 bits (305), Expect = 4e-28
 Identities = 65/188 (34%), Positives = 116/188 (61%), Gaps = 13/188 (6%)

Query: 13  LPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSAL 72
           LP+ +  +  V+YW++ +Q     A ++W+G +     +L   ++P +++LV+GCGNS L
Sbjct: 4   LPKSSREFGSVDYWEKFFQQRGKKA-FEWYGTYLELCGVLHKYIKPREKVLVIGCGNSEL 62

Query: 73  SYELFLGGFPNVTSVDYSSVVVAAMQARHA-HVPQLRWETMDVRKLDFPSASFDVVLEKG 131
           S +L+  G+ ++ ++D S VV+  M+  +A   PQ+ +  MD+ +++FP ASF VVL+KG
Sbjct: 63  SEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKG 122

Query: 132 TLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRTR---HYAQ 188
           TLDA+L  E +      + +  VD++L+EV RVL  GGR++ ++ A  H   +   H+++
Sbjct: 123 TLDAVLTDEEE------KTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSR 176

Query: 189 AYYGWSLR 196
              GW +R
Sbjct: 177 E--GWMVR 182


>gi|55956895 CGI-01 protein isoform 3 [Homo sapiens]
          Length = 543

 Score =  109 bits (272), Expect = 3e-24
 Identities = 56/154 (36%), Positives = 98/154 (63%), Gaps = 8/154 (5%)

Query: 13  LPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSAL 72
           LP+ +  +  V+YW++ +Q     A ++W+G +     +L   ++P +++LV+GCGNS L
Sbjct: 4   LPKSSREFGSVDYWEKFFQQRGKKA-FEWYGTYLELCGVLHKYIKPREKVLVIGCGNSEL 62

Query: 73  SYELFLGGFPNVTSVDYSSVVVAAMQARHA-HVPQLRWETMDVRKLDFPSASFDVVLEKG 131
           S +L+  G+ ++ ++D S VV+  M+  +A   PQ+ +  MD+ +++FP ASF VVL+KG
Sbjct: 63  SEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKG 122

Query: 132 TLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVL 165
           TLDA+L  E +      + +  VD++L+EV RVL
Sbjct: 123 TLDAVLTDEEE------KTLQQVDRMLAEVGRVL 150


>gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]
          Length = 613

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 37/95 (38%), Positives = 60/95 (63%), Gaps = 11/95 (11%)

Query: 105 PQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRV 164
           PQ+ +  MD+ +++FP ASF VVL+KGTLDA+L  E +      + +  VD++L+EV RV
Sbjct: 10  PQMSFLKMDMTQMEFPDASFQVVLDKGTLDAVLTDEEE------KTLQQVDRMLAEVGRV 63

Query: 165 LVPGGRFISMTSAAPHFRTR---HYAQAYYGWSLR 196
           L  GGR++ ++ A  H   +   H+++   GW +R
Sbjct: 64  LQVGGRYLCISLAQAHILKKAVGHFSRE--GWMVR 96


>gi|112734863 methyltransferase like 12 [Homo sapiens]
          Length = 240

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 63/211 (29%), Positives = 90/211 (42%), Gaps = 35/211 (16%)

Query: 26  WDQRY-QGAADSAP-YDWFGDFSSFRALLEPELRPED-----RILVLGCGNSALSYELFL 78
           WD+ + Q    + P +DWF  +   + LL P L+        R+L +GCG S+L   L+ 
Sbjct: 36  WDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYT 95

Query: 79  GG-FP-NVTSVDYSSVVVAAMQARHAHVP------------QLRWETMDVRKLDF--PSA 122
               P +V  VD+S V VA M +     P             L +   D + L     S 
Sbjct: 96  KSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSG 155

Query: 123 SFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFR 182
           SF ++L+KGT DA+  G          G+    Q+LSE  RVL P G  I  +   P  R
Sbjct: 156 SFQLLLDKGTWDAVARG----------GLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVR 205

Query: 183 TRHYAQAYYGWSLRHATYG--SGFHFHLYLM 211
                Q  YGW++     G   G  +  YL+
Sbjct: 206 LPCLEQGSYGWTVTVQELGPFRGITYFAYLI 236


>gi|58219056 methyltransferase like 10 [Homo sapiens]
          Length = 291

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 40/161 (24%), Positives = 69/161 (42%), Gaps = 20/161 (12%)

Query: 24  EYWD-------QRYQGAADSAPYDWFGDFSSFRAL--LEPELRPEDR-ILVLGCGNSALS 73
           E+WD       Q ++   D+    WFG+ S  R +  ++    P D  +L +G GN    
Sbjct: 36  EHWDAVYERELQTFREYGDTGEI-WFGEESMNRLIRWMQKHKIPLDASVLDIGTGNGVFL 94

Query: 74  YELFLGGFPNVTSVDY--SSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKG 131
            EL   GF N+T +DY  S++ ++        +  ++ +  D   L    + F + ++KG
Sbjct: 95  VELAKFGFSNITGIDYSPSAIQLSGSIIEKEGLSNIKLKVEDFLNLSTQLSGFHICIDKG 154

Query: 132 TLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFI 172
           T DA+              +    Q +  +SRVL   G F+
Sbjct: 155 TFDAISLN-------PDNAIEKRKQYVKSLSRVLKVKGFFL 188


>gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]
          Length = 327

 Score = 32.3 bits (72), Expect = 0.41
 Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 15/68 (22%)

Query: 107 LRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLV 166
           L W   D  +L F    FD+         +  G R+        V  +DQ L E  RVL 
Sbjct: 193 LAWVLGDAEELPFDDDKFDIY-------TIAFGIRN--------VTHIDQALQEAHRVLK 237

Query: 167 PGGRFISM 174
           PGGRF+ +
Sbjct: 238 PGGRFLCL 245


>gi|15553097 hypothetical protein MGC9084 [Homo sapiens]
          Length = 372

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 13/34 (38%), Positives = 20/34 (58%)

Query: 61  RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVV 94
           ++L LGCG+  L    F GG   +   DY+S+V+
Sbjct: 190 KVLDLGCGSGLLGITAFKGGSKEIHFQDYNSMVI 223


>gi|4505697 pendrin [Homo sapiens]
          Length = 780

 Score = 30.0 bits (66), Expect = 2.0
 Identities = 11/20 (55%), Positives = 14/20 (70%)

Query: 1  MASPGAGRAPPELPERNCGY 20
          MA+PG    PP+LPE +C Y
Sbjct: 1  MAAPGGRSEPPQLPEYSCSY 20


>gi|31340735 zinc finger protein 445 [Homo sapiens]
          Length = 1031

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 20/64 (31%), Positives = 26/64 (40%), Gaps = 2/64 (3%)

Query: 158 LSEVSRVLVPGGRFISMTSAAPHFR--TRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGG 215
           L  V+ + V G +         HFR  + HY    YG  LRH   G   H  ++   KG 
Sbjct: 398 LKHVTYLRVSGRKESLKHGCGKHFRMSSHHYDYKKYGKGLRHMIGGFSLHQRIHSGLKGN 457

Query: 216 KLSV 219
           K  V
Sbjct: 458 KKDV 461


>gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform 1
           [Homo sapiens]
          Length = 640

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 5/82 (6%)

Query: 56  LRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVR 115
           L PE+  L+    +S L Y +     P+VT  DYS ++ A +       P +RW      
Sbjct: 286 LDPENLALLEKIQSSLLVYSME-DSSPHVTPEDYSEIIAAILIGD----PTVRWGDKSYN 340

Query: 116 KLDFPSASFDVVLEKGTLDALL 137
            + F +  F    +    DA++
Sbjct: 341 LISFSNGVFGCNCDHAPFDAMI 362


>gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform 2
           [Homo sapiens]
          Length = 612

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 5/82 (6%)

Query: 56  LRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVR 115
           L PE+  L+    +S L Y +     P+VT  DYS ++ A +       P +RW      
Sbjct: 258 LDPENLALLEKIQSSLLVYSME-DSSPHVTPEDYSEIIAAILIGD----PTVRWGDKSYN 312

Query: 116 KLDFPSASFDVVLEKGTLDALL 137
            + F +  F    +    DA++
Sbjct: 313 LISFSNGVFGCNCDHAPFDAMI 334


>gi|37588873 ring finger protein 128 isoform 1 [Homo sapiens]
          Length = 428

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 15/40 (37%), Positives = 21/40 (52%)

Query: 141 RDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPH 180
           R  W +S EGV+  D  L  V+ VLVP     ++ +  PH
Sbjct: 60  RTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPH 99


>gi|89145417 methyltransferase like 7A [Homo sapiens]
          Length = 244

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 15/36 (41%), Positives = 19/36 (52%)

Query: 151 VHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRTRHY 186
           V   +++L EV RVL PGG F  M   A    T +Y
Sbjct: 150 VKNQERILREVCRVLRPGGAFYFMEHVAAECSTWNY 185


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 28.1 bits (61), Expect = 7.8
 Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 6/112 (5%)

Query: 82   PNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGER 141
            PN+  +DY   +        A VPQ+  ET  V   D    + D V  +  L   LA E 
Sbjct: 2530 PNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLA-EH 2588

Query: 142  DPWTV----SSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRT-RHYAQ 188
             P  +     S    T+   L  +  + V G  F S T+     +T  HY +
Sbjct: 2589 KPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE 2640


>gi|153251913 hypothetical protein LOC57604 isoform 1 [Homo sapiens]
          Length = 454

 Score = 28.1 bits (61), Expect = 7.8
 Identities = 37/156 (23%), Positives = 57/156 (36%), Gaps = 29/156 (18%)

Query: 36  SAPYDWFGDFSS-----FRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYS 90
           +APY  F D  S      R  L+ E +P   I  +GCG       L +    +    DY 
Sbjct: 20  TAPY--FSDLQSKAWPRVRQFLQ-EQKPGSLIADIGCGTGKY---LKVNSQVHTVGCDYC 73

Query: 91  SVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEG 150
             +V   + R            D   L F    FD ++  G +      +R         
Sbjct: 74  GPLVEIARNRGCEAM-----VCDNLNLPFRDEGFDAIISIGVIHHFSTKQRRI------- 121

Query: 151 VHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRTRHY 186
                + + E++RVLVPGG+ +    A    + RH+
Sbjct: 122 -----RAIKEMARVLVPGGQLMIYVWAMEQ-KNRHF 151


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,979,253
Number of Sequences: 37866
Number of extensions: 483035
Number of successful extensions: 1255
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1236
Number of HSP's gapped (non-prelim): 17
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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