Search of human proteins with 153791347

Search of human proteins with 153791347

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153791347 doublecortin domain containing 1 [Homo sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153791347 doublecortin domain containing 1 [Homo sapiens]          702   0.0  
gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo s...    44   2e-04
gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo s...    44   2e-04
gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo s...    44   2e-04
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    34   0.17 
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]                  33   0.51 
gi|30181244 doublecortin isoform c [Homo sapiens]                      32   1.1  
gi|30181242 doublecortin isoform b [Homo sapiens]                      32   1.1  
gi|30181240 doublecortin isoform c [Homo sapiens]                      32   1.1  
gi|30181246 doublecortin isoform a [Homo sapiens]                      32   1.1  
gi|117414154 sodium channel associated protein 2 isoform b [Homo...    31   1.5  
gi|117414162 sodium channel associated protein 2 isoform a [Homo...    31   1.5  
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]       31   1.9  
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]       31   1.9  
gi|154800469 lung cancer-related protein 8 isoform c [Homo sapiens]    31   1.9  
gi|154800467 lung cancer-related protein 8 isoform b [Homo sapiens]    31   1.9  
gi|21361664 lung cancer-related protein 8 isoform a [Homo sapiens]     31   1.9  
gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Hom...    30   3.3  
gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Hom...    30   3.3  
gi|4758128 doublecortin-like kinase 1 [Homo sapiens]                   30   3.3  
gi|59806363 hypothetical protein LOC9729 [Homo sapiens]                30   4.3  
gi|23510360 Ras association domain family 4 [Homo sapiens]             29   5.6  
gi|149944526 additional sex combs like 3 [Homo sapiens]                29   7.3  
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ...    28   9.5  

>gi|153791347 doublecortin domain containing 1 [Homo sapiens]
          Length = 354

 Score =  702 bits (1812), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MAKTGAEDHREALSQSSLSLLTEAMEVLQQSSPEGTLDGNTVNPIYKYILNDLPREFMSS 60
           MAKTGAEDHREALSQSSLSLLTEAMEVLQQSSPEGTLDGNTVNPIYKYILNDLPREFMSS
Sbjct: 1   MAKTGAEDHREALSQSSLSLLTEAMEVLQQSSPEGTLDGNTVNPIYKYILNDLPREFMSS 60

Query: 61  QAKAVIKTTDDYLQSQFGPNRLVHSAAVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSN 120
           QAKAVIKTTDDYLQSQFGPNRLVHSAAVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSN
Sbjct: 61  QAKAVIKTTDDYLQSQFGPNRLVHSAAVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSN 120

Query: 121 SKNNSCSISASKRNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKVTAYK 180
           SKNNSCSISASKRNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKVTAYK
Sbjct: 121 SKNNSCSISASKRNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKVTAYK 180

Query: 181 NGSRTVFARVTVPTITLLLEECTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTG 240
           NGSRTVFARVTVPTITLLLEECTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTG
Sbjct: 181 NGSRTVFARVTVPTITLLLEECTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTG 240

Query: 241 EPFLNPFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRMKKLTERTSVRILFF 300
           EPFLNPFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRMKKLTERTSVRILFF
Sbjct: 241 EPFLNPFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRMKKLTERTSVRILFF 300

Query: 301 KNGMGQDGHEITVGKETMKKVLDTCTIRMNLNLPARYFYDLYGRKIEDISKGKH 354
           KNGMGQDGHEITVGKETMKKVLDTCTIRMNLNLPARYFYDLYGRKIEDISKGKH
Sbjct: 301 KNGMGQDGHEITVGKETMKKVLDTCTIRMNLNLPARYFYDLYGRKIEDISKGKH 354


>gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo
           sapiens]
          Length = 1020

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 22/45 (48%), Positives = 29/45 (64%)

Query: 202 CTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNP 246
           CTE LNL  AARR++   GKE    +D+  +  VYVS GE ++NP
Sbjct: 118 CTEILNLPSAARRLYNEKGKEIFALKDLQRDELVYVSCGELWINP 162



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 13/115 (11%)

Query: 128 ISASKRNRP-VSAPVGQLRVAEFS-----------SLKFQSARNWQKLSQRHKLQPRVIK 175
           IS +K  +P +  P   + VAE             SL+ ++       S       + +K
Sbjct: 588 ISGTKTQKPFLQGPFKVISVAEAEKTLSYYQARLLSLRMKTCTQAASHSGMAATHQKAVK 647

Query: 176 VTAYKNGSRTVFARVTVP-TITLLLEECTEKLNLNMAARRVFLADGKEALEPEDI 229
           + AYKNG      ++ V  T  +LL ECTE+L L  AA +V+  DG       D+
Sbjct: 648 IIAYKNGDGYRNGKLIVAGTFPMLLTECTEQLGLARAASKVYTKDGTPIFTLRDL 702



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 170 QPRVIKVTAYKNGSRTVFARVTV-PTITLLLEECTEKLNLNMAARRVFLADGKEALEPED 228
           QP   +V  Y NG R          TI+ LL++C+ +L +   AR ++   G+     +D
Sbjct: 900 QPNTKRVWIYLNGGRPEDGTYAWGKTISELLQDCSSRLKMTHPARALYTPSGEPIQSWDD 959

Query: 229 IPHEADVYVSTGEPFLNPFKKIK 251
           I  +  + VS G  F  P K++K
Sbjct: 960 IERDMVICVSMGHGFKTP-KELK 981


>gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo
           sapiens]
          Length = 1020

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 22/45 (48%), Positives = 29/45 (64%)

Query: 202 CTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNP 246
           CTE LNL  AARR++   GKE    +D+  +  VYVS GE ++NP
Sbjct: 118 CTEILNLPSAARRLYNEKGKEIFALKDLQRDELVYVSCGELWINP 162



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 13/115 (11%)

Query: 128 ISASKRNRP-VSAPVGQLRVAEFS-----------SLKFQSARNWQKLSQRHKLQPRVIK 175
           IS +K  +P +  P   + VAE             SL+ ++       S       + +K
Sbjct: 588 ISGTKTQKPFLQGPFKVISVAEAEKTLSYYQARLLSLRMKTCTQAASHSGMAATHQKAVK 647

Query: 176 VTAYKNGSRTVFARVTVP-TITLLLEECTEKLNLNMAARRVFLADGKEALEPEDI 229
           + AYKNG      ++ V  T  +LL ECTE+L L  AA +V+  DG       D+
Sbjct: 648 IIAYKNGDGYRNGKLIVAGTFPMLLTECTEQLGLARAASKVYTKDGTPIFTLRDL 702



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 170 QPRVIKVTAYKNGSRTVFARVTV-PTITLLLEECTEKLNLNMAARRVFLADGKEALEPED 228
           QP   +V  Y NG R          TI+ LL++C+ +L +   AR ++   G+     +D
Sbjct: 900 QPNTKRVWIYLNGGRPEDGTYAWGKTISELLQDCSSRLKMTHPARALYTPSGEPIQSWDD 959

Query: 229 IPHEADVYVSTGEPFLNPFKKIK 251
           I  +  + VS G  F  P K++K
Sbjct: 960 IERDMVICVSMGHGFKTP-KELK 981


>gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo
           sapiens]
          Length = 1020

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 22/45 (48%), Positives = 29/45 (64%)

Query: 202 CTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNP 246
           CTE LNL  AARR++   GKE    +D+  +  VYVS GE ++NP
Sbjct: 118 CTEILNLPSAARRLYNEKGKEIFALKDLQRDELVYVSCGELWINP 162



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 13/115 (11%)

Query: 128 ISASKRNRP-VSAPVGQLRVAEFS-----------SLKFQSARNWQKLSQRHKLQPRVIK 175
           IS +K  +P +  P   + VAE             SL+ ++       S       + +K
Sbjct: 588 ISGTKTQKPFLQGPFKVISVAEAEKTLSYYQARLLSLRMKTCTQAASHSGMAATHQKAVK 647

Query: 176 VTAYKNGSRTVFARVTVP-TITLLLEECTEKLNLNMAARRVFLADGKEALEPEDI 229
           + AYKNG      ++ V  T  +LL ECTE+L L  AA +V+  DG       D+
Sbjct: 648 IIAYKNGDGYRNGKLIVAGTFPMLLTECTEQLGLARAASKVYTKDGTPIFTLRDL 702



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 170 QPRVIKVTAYKNGSRTVFARVTV-PTITLLLEECTEKLNLNMAARRVFLADGKEALEPED 228
           QP   +V  Y NG R          TI+ LL++C+ +L +   AR ++   G+     +D
Sbjct: 900 QPNTKRVWIYLNGGRPEDGTYAWGKTISELLQDCSSRLKMTHPARALYTPSGEPIQSWDD 959

Query: 229 IPHEADVYVSTGEPFLNPFKKIK 251
           I  +  + VS G  F  P K++K
Sbjct: 960 IERDMVICVSMGHGFKTP-KELK 981


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 4/71 (5%)

Query: 69  TDDY----LQSQFGPNRLVHSAAVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSNSKNN 124
           T+D+    L++   PNR +H+++ S  S     S+  ++S  S    S   S  S+S ++
Sbjct: 128 TEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 187

Query: 125 SCSISASKRNR 135
           S S S SK ++
Sbjct: 188 SSSTSFSKPHK 198


>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
          Length = 1966

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 4/109 (3%)

Query: 32   SPEGTLDGNTVNPIYKYILNDLPREFMSSQAKAVIKTTDDYLQSQFGPNRLVHSAAVSEG 91
            SP+GT      +P+    +N      +SSQA A +       +S      +  S + S  
Sbjct: 1620 SPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQPSPSTSSL 1679

Query: 92   SGLQDCSTHQTASDHSHDEISDLDSYK-SNSKNNSCSISASKRNRPVSA 139
            S     S + T+S  S    S L S K  +S+ NSC    S R RP SA
Sbjct: 1680 SSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSC---LSPRERPCSA 1725


>gi|30181244 doublecortin isoform c [Homo sapiens]
          Length = 360

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 17/108 (15%)

Query: 154 FQSARNWQKLSQRHKLQPRVIKVTAYKNGSR----TVFA------RVTVPTITLLLEECT 203
           F   R  Q LS   K +    KV  Y+NG R     V+A      R     +  L    +
Sbjct: 37  FYRTRTLQALSNEKKAK----KVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLS 92

Query: 204 EKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNPFKKIK 251
           + +NL    R ++  DG   +   D   E + YV + + F   FKK++
Sbjct: 93  DNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNF---FKKVE 137


>gi|30181242 doublecortin isoform b [Homo sapiens]
          Length = 365

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 17/108 (15%)

Query: 154 FQSARNWQKLSQRHKLQPRVIKVTAYKNGSR----TVFA------RVTVPTITLLLEECT 203
           F   R  Q LS   K +    KV  Y+NG R     V+A      R     +  L    +
Sbjct: 37  FYRTRTLQALSNEKKAK----KVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLS 92

Query: 204 EKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNPFKKIK 251
           + +NL    R ++  DG   +   D   E + YV + + F   FKK++
Sbjct: 93  DNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNF---FKKVE 137


>gi|30181240 doublecortin isoform c [Homo sapiens]
          Length = 360

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 17/108 (15%)

Query: 154 FQSARNWQKLSQRHKLQPRVIKVTAYKNGSR----TVFA------RVTVPTITLLLEECT 203
           F   R  Q LS   K +    KV  Y+NG R     V+A      R     +  L    +
Sbjct: 37  FYRTRTLQALSNEKKAK----KVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLS 92

Query: 204 EKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNPFKKIK 251
           + +NL    R ++  DG   +   D   E + YV + + F   FKK++
Sbjct: 93  DNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNF---FKKVE 137


>gi|30181246 doublecortin isoform a [Homo sapiens]
          Length = 441

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 17/108 (15%)

Query: 154 FQSARNWQKLSQRHKLQPRVIKVTAYKNGSR----TVFA------RVTVPTITLLLEECT 203
           F   R  Q LS   K +    KV  Y+NG R     V+A      R     +  L    +
Sbjct: 118 FYRTRTLQALSNEKKAK----KVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLS 173

Query: 204 EKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNPFKKIK 251
           + +NL    R ++  DG   +   D   E + YV + + F   FKK++
Sbjct: 174 DNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNF---FKKVE 218


>gi|117414154 sodium channel associated protein 2 isoform b [Homo
           sapiens]
          Length = 939

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 14/164 (8%)

Query: 14  SQSSLSLLTEAMEVLQQSSPEGTLDGNTV-NPIYKYILNDLPREFMSSQAKAVIKTTDDY 72
           S  S ++LT  M V Q S PE     N + N I    L+D   + ++  + ++    D+ 
Sbjct: 170 STPSDAVLTSFMSVCQSSEPEKNNHENDLQNEIKLQKLDDQILQLLNETSNSI----DNV 225

Query: 73  LQSQFGPNRLVHSAAVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSNSKNNSCSISASK 132
           L+    P R     + S+    ++C+           +   + + K ++KN +  +S ++
Sbjct: 226 LEKDPRPKRDTDITSESDYGNRKECNRKVPRRSKIPYDAKTIQTIKHHNKNYNSFVSCNR 285

Query: 133 RNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKV 176
           + +P       L+    SS    S  N   L +  K +  +IKV
Sbjct: 286 KMKP-----PYLKELYVSS----SLANCPMLQESEKPKTEIIKV 320


>gi|117414162 sodium channel associated protein 2 isoform a [Homo
           sapiens]
          Length = 1032

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 14/164 (8%)

Query: 14  SQSSLSLLTEAMEVLQQSSPEGTLDGNTV-NPIYKYILNDLPREFMSSQAKAVIKTTDDY 72
           S  S ++LT  M V Q S PE     N + N I    L+D   + ++  + ++    D+ 
Sbjct: 263 STPSDAVLTSFMSVCQSSEPEKNNHENDLQNEIKLQKLDDQILQLLNETSNSI----DNV 318

Query: 73  LQSQFGPNRLVHSAAVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSNSKNNSCSISASK 132
           L+    P R     + S+    ++C+           +   + + K ++KN +  +S ++
Sbjct: 319 LEKDPRPKRDTDITSESDYGNRKECNRKVPRRSKIPYDAKTIQTIKHHNKNYNSFVSCNR 378

Query: 133 RNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKV 176
           + +P       L+    SS    S  N   L +  K +  +IKV
Sbjct: 379 KMKP-----PYLKELYVSS----SLANCPMLQESEKPKTEIIKV 413


>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
          Length = 765

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 35/134 (26%), Positives = 51/134 (38%), Gaps = 21/134 (15%)

Query: 121 SKNNSCSISASKRNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKVTAYK 180
           S +   S S  K N  + +P      A  +   F   R  Q LS   K +    K   Y+
Sbjct: 29  SSSGGSSSSGPKGNGLIPSP------AHSAHCSFYRTRTLQALSSEKKAK----KARFYR 78

Query: 181 NGSR----TVFA------RVTVPTITLLLEECTEKLNLNMAARRVFLADGKEALEPEDIP 230
           NG R     VFA      R     +  L    ++ +NL    R ++  DG   +   D  
Sbjct: 79  NGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDEL 138

Query: 231 HEADVYV-STGEPF 243
            E + YV ++ EPF
Sbjct: 139 LEGESYVCASNEPF 152


>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
          Length = 766

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 35/134 (26%), Positives = 51/134 (38%), Gaps = 21/134 (15%)

Query: 121 SKNNSCSISASKRNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKVTAYK 180
           S +   S S  K N  + +P      A  +   F   R  Q LS   K +    K   Y+
Sbjct: 29  SSSGGSSSSGPKGNGLIPSP------AHSAHCSFYRTRTLQALSSEKKAK----KARFYR 78

Query: 181 NGSR----TVFA------RVTVPTITLLLEECTEKLNLNMAARRVFLADGKEALEPEDIP 230
           NG R     VFA      R     +  L    ++ +NL    R ++  DG   +   D  
Sbjct: 79  NGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDEL 138

Query: 231 HEADVYV-STGEPF 243
            E + YV ++ EPF
Sbjct: 139 LEGESYVCASNEPF 152


>gi|154800469 lung cancer-related protein 8 isoform c [Homo sapiens]
          Length = 583

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 5/44 (11%)

Query: 246 PFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRMKKL 289
           PFK++K HL   K +     G  +PTD K  ++KP    R KK+
Sbjct: 17  PFKRLKSHLPYCKMI-----GPTIPTDQKVYQSKPATLPRAKKM 55


>gi|154800467 lung cancer-related protein 8 isoform b [Homo sapiens]
          Length = 573

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 5/44 (11%)

Query: 246 PFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRMKKL 289
           PFK++K HL   K +     G  +PTD K  ++KP    R KK+
Sbjct: 17  PFKRLKSHLPYCKMI-----GPTIPTDQKVYQSKPATLPRAKKM 55


>gi|21361664 lung cancer-related protein 8 isoform a [Homo sapiens]
          Length = 609

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 5/44 (11%)

Query: 246 PFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRMKKL 289
           PFK++K HL   K +     G  +PTD K  ++KP    R KK+
Sbjct: 17  PFKRLKSHLPYCKMI-----GPTIPTDQKVYQSKPATLPRAKKM 55


>gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Homo
           sapiens]
          Length = 1800

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 35/164 (21%), Positives = 61/164 (37%), Gaps = 23/164 (14%)

Query: 37  LDGNTVNPIYKYILND-----LPREFMSSQAKAVIKTTDDYLQSQFGPNRLVHSAAVSEG 91
           +DG+    I  Y++ D       +E    + +A++    + L   F   R     A    
Sbjct: 777 VDGDAPEDIADYMVEDNFVLESEKEKFVEELRAIVGQAQEILHVHFATER-----ATGVD 831

Query: 92  SGLQDCSTHQTASDHSHDEISDLDSYKSNSKNNSCSISASKRNRPVSAPVGQLRVAEFSS 151
           S   D ++ QT S                 + NS S   S  + P S+PVG+ R     +
Sbjct: 832 SITVDSNSSQTGSSEQ-------------VQINSTSTQTSNESAPQSSPVGRWRFCINQT 878

Query: 152 LKFQSARNWQKLSQRHKLQPRVIKVTAYKNGSRTVFARVTVPTI 195
           ++ +  ++   L       P    + + KN S    +R T+ TI
Sbjct: 879 IRNRETQSPPSLQHSMSAVPGRHPLPSPKNTSNKEISRDTLLTI 922


>gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Homo
           sapiens]
          Length = 1743

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 35/164 (21%), Positives = 61/164 (37%), Gaps = 23/164 (14%)

Query: 37  LDGNTVNPIYKYILND-----LPREFMSSQAKAVIKTTDDYLQSQFGPNRLVHSAAVSEG 91
           +DG+    I  Y++ D       +E    + +A++    + L   F   R     A    
Sbjct: 777 VDGDAPEDIADYMVEDNFVLESEKEKFVEELRAIVGQAQEILHVHFATER-----ATGVD 831

Query: 92  SGLQDCSTHQTASDHSHDEISDLDSYKSNSKNNSCSISASKRNRPVSAPVGQLRVAEFSS 151
           S   D ++ QT S                 + NS S   S  + P S+PVG+ R     +
Sbjct: 832 SITVDSNSSQTGSSEQ-------------VQINSTSTQTSNESAPQSSPVGRWRFCINQT 878

Query: 152 LKFQSARNWQKLSQRHKLQPRVIKVTAYKNGSRTVFARVTVPTI 195
           ++ +  ++   L       P    + + KN S    +R T+ TI
Sbjct: 879 IRNRETQSPPSLQHSMSAVPGRHPLPSPKNTSNKEISRDTLLTI 922


>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
          Length = 729

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 17/108 (15%)

Query: 154 FQSARNWQKLSQRHKLQPRVIKVTAYKNGSR----TVFA------RVTVPTITLLLEECT 203
           F   R  Q LS   K +    KV  Y+NG R     V+A      R     +  L    +
Sbjct: 41  FYRTRTLQTLSSEKKAK----KVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLS 96

Query: 204 EKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNPFKKIK 251
           + +NL    R ++  DG + +   D   E + YV      + PFKK++
Sbjct: 97  DNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGS---IEPFKKLE 141


>gi|59806363 hypothetical protein LOC9729 [Homo sapiens]
          Length = 694

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 5/61 (8%)

Query: 107 SHDEISDLDSYKSNSKNNSCSISASKRNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQR 166
           S+D  S +    S  +N SC    + RN  ++A     +  EF+   F++ RN Q + Q 
Sbjct: 408 SNDCSSSVAESSSPLRNFSCGFERTTRNEKLAA-----KTDEFNRTVFRTDRNCQAIQQN 462

Query: 167 H 167
           H
Sbjct: 463 H 463


>gi|23510360 Ras association domain family 4 [Homo sapiens]
          Length = 321

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 10/75 (13%)

Query: 179 YKNGSRTVFARVTVPTITLLLEECTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVS 238
           +++G RT       P I+ +L    EK+       R+FL +    +E   +PHE   Y+ 
Sbjct: 225 HESGERTKLKDCEYPLISRILHGPCEKI------ARIFLMEADLGVE---VPHEVAQYIK 275

Query: 239 TGEPFLNPF-KKIKD 252
              P L+ F +K+K+
Sbjct: 276 FEMPVLDSFVEKLKE 290


>gi|149944526 additional sex combs like 3 [Homo sapiens]
          Length = 2248

 Score = 28.9 bits (63), Expect = 7.3
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 22/112 (19%)

Query: 31   SSPEGTLDGNT----VNPIYKYILNDLPREFMSSQAKAVIKTTDDYLQSQFGPNRLVHSA 86
            S+PE  ++G+T    VNP  +            S   A ++ T   LQ    P++L  +A
Sbjct: 1146 STPETKMEGSTGVIIVNPNCR----------SPSNKSAHLRETTTVLQQSLNPSKLPETA 1195

Query: 87   AVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSNSKNNSCSISASKRNRPVS 138
                     D S H +  +     +S+     ++S+N+S  +  +K + PVS
Sbjct: 1196 T--------DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVS 1239


>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
           [Homo sapiens]
          Length = 1099

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 31/126 (24%), Positives = 56/126 (44%), Gaps = 8/126 (6%)

Query: 170 QPRVIKVTAYK--NGSRTVFARVTVPTITLLLEECTEKLNL-NMAARRVFLADGKEALEP 226
           +PR + V ++K  NGS   F + +   I L++E C   +NL  +  + +F   G + +E 
Sbjct: 492 RPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQ-VEV 550

Query: 227 EDIPHEADVYVSTGEPFLNPFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRM 286
            DI +  +     GE  L   +  +D   +   +     GL  P   K R    + +I++
Sbjct: 551 NDIKNSFE----RGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKL 606

Query: 287 KKLTER 292
           +   ER
Sbjct: 607 ENPAER 612


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,307,258
Number of Sequences: 37866
Number of extensions: 504467
Number of successful extensions: 1411
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1392
Number of HSP's gapped (non-prelim): 31
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.