Guide to the Human Genome
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Search of human proteins with 153085461

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153085461 HIG1 domain family, member 1A isoform a [Homo
sapiens]
         (107 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]   213   2e-56
gi|153085470 HIG1 domain family, member 1A isoform b [Homo sapiens]   189   5e-49
gi|153085463 HIG1 domain family, member 1A isoform b [Homo sapiens]   189   5e-49
gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A...   179   6e-46
gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A...   179   6e-46
gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo ...   179   6e-46
gi|157817101 HIG1 domain family, member 1C [Homo sapiens]             108   9e-25
gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo...    89   8e-19
gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Hom...    55   9e-09
gi|169202111 PREDICTED: similar to HIG1 domain family, member 2A...    27   2.7  
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo...    26   6.1  
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo...    26   6.1  

>gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]
          Length = 107

 Score =  213 bits (543), Expect = 2e-56
 Identities = 107/107 (100%), Positives = 107/107 (100%)

Query: 1   MEQKLVEEILQAITMSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLY 60
           MEQKLVEEILQAITMSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLY
Sbjct: 1   MEQKLVEEILQAITMSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLY 60

Query: 61  KLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107
           KLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP
Sbjct: 61  KLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107


>gi|153085470 HIG1 domain family, member 1A isoform b [Homo sapiens]
          Length = 93

 Score =  189 bits (479), Expect = 5e-49
 Identities = 93/93 (100%), Positives = 93/93 (100%)

Query: 15  MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL 74
           MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL
Sbjct: 1   MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL 60

Query: 75  IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107
           IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP
Sbjct: 61  IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 93


>gi|153085463 HIG1 domain family, member 1A isoform b [Homo sapiens]
          Length = 93

 Score =  189 bits (479), Expect = 5e-49
 Identities = 93/93 (100%), Positives = 93/93 (100%)

Query: 15  MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL 74
           MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL
Sbjct: 1   MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHL 60

Query: 75  IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107
           IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP
Sbjct: 61  IHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 93


>gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score =  179 bits (453), Expect = 6e-46
 Identities = 86/102 (84%), Positives = 94/102 (92%)

Query: 6   VEEILQAITMSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSR 65
           + EILQA+ +STDT VSL SY+E QGSKLIRKAKE P VPVGIAGFAA+V YGLYKLKSR
Sbjct: 23  IREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSR 82

Query: 66  GNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107
           GNT+MS+HLIHMRVAAQGFVVGAMT+GMGYSMYREFWAKPKP
Sbjct: 83  GNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWAKPKP 124


>gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score =  179 bits (453), Expect = 6e-46
 Identities = 86/102 (84%), Positives = 94/102 (92%)

Query: 6   VEEILQAITMSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSR 65
           + EILQA+ +STDT VSL SY+E QGSKLIRKAKE P VPVGIAGFAA+V YGLYKLKSR
Sbjct: 23  IREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSR 82

Query: 66  GNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107
           GNT+MS+HLIHMRVAAQGFVVGAMT+GMGYSMYREFWAKPKP
Sbjct: 83  GNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWAKPKP 124


>gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo
           sapiens]
          Length = 124

 Score =  179 bits (453), Expect = 6e-46
 Identities = 86/102 (84%), Positives = 94/102 (92%)

Query: 6   VEEILQAITMSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSR 65
           + EILQA+ +STDT VSL SY+E QGSKLIRKAKE P VPVGIAGFAA+V YGLYKLKSR
Sbjct: 23  IREILQAVIISTDTDVSLSSYDEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSR 82

Query: 66  GNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP 107
           GNT+MS+HLIHMRVAAQGFVVGAMT+GMGYSMYREFWAKPKP
Sbjct: 83  GNTQMSLHLIHMRVAAQGFVVGAMTIGMGYSMYREFWAKPKP 124


>gi|157817101 HIG1 domain family, member 1C [Homo sapiens]
          Length = 97

 Score =  108 bits (270), Expect = 9e-25
 Identities = 52/79 (65%), Positives = 69/79 (87%), Gaps = 2/79 (2%)

Query: 25  SYEEDQG--SKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQ 82
           S +ED+G  S+LIRK++++PFVP+GIAGF  +V+ GLYKLK R + KMSIHLIHMRVAAQ
Sbjct: 8   SADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIHLIHMRVAAQ 67

Query: 83  GFVVGAMTVGMGYSMYREF 101
           GFVVGA+T+G+ YSMY+++
Sbjct: 68  GFVVGAVTLGVLYSMYKDY 86


>gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo
           sapiens]
          Length = 99

 Score = 89.0 bits (219), Expect = 8e-19
 Identities = 40/78 (51%), Positives = 56/78 (71%)

Query: 24  PSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQG 83
           P  E+    KL+RK +E+P VP+G+ G   + AY +Y+L+SRG+TKMSIHLIH RVAAQ 
Sbjct: 11  PDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQA 70

Query: 84  FVVGAMTVGMGYSMYREF 101
             VGA+ +G  Y+MY ++
Sbjct: 71  CAVGAIMLGAVYTMYSDY 88


>gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Homo
          sapiens]
          Length = 106

 Score = 55.5 bits (132), Expect = 9e-09
 Identities = 27/61 (44%), Positives = 39/61 (63%), Gaps = 1/61 (1%)

Query: 33 KLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVG 92
          K +RK +E P VP+G    AA + YGLY    RGN++ S  ++  R+AAQGF V A+ +G
Sbjct: 38 KFVRKTRENPVVPIGCLATAAALTYGLYSF-HRGNSQRSQLMMRTRIAAQGFTVAAILLG 96

Query: 93 M 93
          +
Sbjct: 97 L 97


>gi|169202111 PREDICTED: similar to HIG1 domain family, member 2A
           [Homo sapiens]
          Length = 103

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/61 (24%), Positives = 30/61 (49%)

Query: 37  KAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYS 96
           K  + P VP+G    A  + Y L+    +G+++    +    +  QGF V A+ + + +S
Sbjct: 41  KTCKNPTVPIGCLSKAITLTYSLFYCFYQGHSQCFQLMTRTCITTQGFTVTAILLHLLWS 100

Query: 97  M 97
           +
Sbjct: 101 L 101


>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
           sapiens]
          Length = 342

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 44  VPVGIA---GFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYRE 100
           VP G+A   GF AI        +S  N  + I + +     +G  V     G G+S +R 
Sbjct: 206 VPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNF---PEGLAVSLPLRGAGFSTWRA 262

Query: 101 FW 102
           FW
Sbjct: 263 FW 264


>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
           sapiens]
          Length = 335

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 44  VPVGIA---GFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYRE 100
           VP G+A   GF AI        +S  N  + I + +     +G  V     G G+S +R 
Sbjct: 199 VPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNF---PEGLAVSLPLRGAGFSTWRA 255

Query: 101 FW 102
           FW
Sbjct: 256 FW 257


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,758,453
Number of Sequences: 37866
Number of extensions: 132619
Number of successful extensions: 218
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 207
Number of HSP's gapped (non-prelim): 12
length of query: 107
length of database: 18,247,518
effective HSP length: 77
effective length of query: 30
effective length of database: 15,331,836
effective search space: 459955080
effective search space used: 459955080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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