Guide to the Human Genome
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Search of human proteins with 151301127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
         (4024 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]          8087   0.0  
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]           4036   0.0  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]          3158   0.0  
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]    2631   0.0  
gi|75677365 dynein heavy chain domain 3 [Homo sapiens]               2454   0.0  
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]    2092   0.0  
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]         2056   0.0  
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s...  1980   0.0  
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s...  1946   0.0  
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s...  1945   0.0  
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap...  1941   0.0  
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]           1918   0.0  
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]          1909   0.0  
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]    1900   0.0  
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]        1308   0.0  
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]     1268   0.0  
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...   937   0.0  
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap...   478   e-134
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]     225   6e-58
gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens]      137   3e-31
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       46   7e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       46   7e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        46   7e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     44   0.002
gi|110347443 TATA element modulatory factor 1 [Homo sapiens]           44   0.003
gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]             42   0.016
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           41   0.027
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           41   0.027
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           41   0.027
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    39   0.080

>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
          Length = 4024

 Score = 8087 bits (20983), Expect = 0.0
 Identities = 4024/4024 (100%), Positives = 4024/4024 (100%)

Query: 1    MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPS 60
            MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPS
Sbjct: 1    MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPS 60

Query: 61   FHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKE 120
            FHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKE
Sbjct: 61   FHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKE 120

Query: 121  RENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPM 180
            RENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPM
Sbjct: 121  RENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPM 180

Query: 181  EDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTD 240
            EDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTD
Sbjct: 181  EDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTD 240

Query: 241  ELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEF 300
            ELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEF
Sbjct: 241  ELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEF 300

Query: 301  HNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESF 360
            HNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESF
Sbjct: 301  HNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESF 360

Query: 361  FNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELS 420
            FNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELS
Sbjct: 361  FNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELS 420

Query: 421  DYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVI 480
            DYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVI
Sbjct: 421  DYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVI 480

Query: 481  MKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTS 540
            MKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTS
Sbjct: 481  MKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTS 540

Query: 541  IKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALST 600
            IKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALST
Sbjct: 541  IKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALST 600

Query: 601  PPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWY 660
            PPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWY
Sbjct: 601  PPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWY 660

Query: 661  GRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLK 720
            GRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLK
Sbjct: 661  GRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLK 720

Query: 721  KAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNY 780
            KAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNY
Sbjct: 721  KAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNY 780

Query: 781  RAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPL 840
            RAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPL
Sbjct: 781  RAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPL 840

Query: 841  IQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYS 900
            IQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYS
Sbjct: 841  IQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYS 900

Query: 901  LEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYE 960
            LEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYE
Sbjct: 901  LEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYE 960

Query: 961  KQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDI 1020
            KQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDI
Sbjct: 961  KQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDI 1020

Query: 1021 MRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELL 1080
            MRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELL
Sbjct: 1021 MRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELL 1080

Query: 1081 EILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQV 1140
            EILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQV
Sbjct: 1081 EILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQV 1140

Query: 1141 EKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIP 1200
            EKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIP
Sbjct: 1141 EKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIP 1200

Query: 1201 MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260
            MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD
Sbjct: 1201 MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260

Query: 1261 DSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL 1320
            DSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL
Sbjct: 1261 DSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL 1320

Query: 1321 HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFD 1380
            HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFD
Sbjct: 1321 HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFD 1380

Query: 1381 EFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSEL 1440
            EFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSEL
Sbjct: 1381 EFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSEL 1440

Query: 1441 PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY 1500
            PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY
Sbjct: 1441 PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY 1500

Query: 1501 GMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVK 1560
            GMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVK
Sbjct: 1501 GMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVK 1560

Query: 1561 LPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYR 1620
            LPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYR
Sbjct: 1561 LPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYR 1620

Query: 1621 VLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFAS 1680
            VLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFAS
Sbjct: 1621 VLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFAS 1680

Query: 1681 SVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVAS 1740
            SVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVAS
Sbjct: 1681 SVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVAS 1740

Query: 1741 PATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKH 1800
            PATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKH
Sbjct: 1741 PATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKH 1800

Query: 1801 TKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGAS 1860
            TKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGAS
Sbjct: 1801 TKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGAS 1860

Query: 1861 CTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVT 1920
            CTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVT
Sbjct: 1861 CTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVT 1920

Query: 1921 EGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGT 1980
            EGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGT
Sbjct: 1921 EGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGT 1980

Query: 1981 GKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMV 2040
            GKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMV
Sbjct: 1981 GKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMV 2040

Query: 2041 VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRN 2100
            VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRN
Sbjct: 2041 VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRN 2100

Query: 2101 PVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLY 2160
            PVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLY
Sbjct: 2101 PVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLY 2160

Query: 2161 KEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRL 2220
            KEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRL
Sbjct: 2161 KEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRL 2220

Query: 2221 LDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRED 2280
            LDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRED
Sbjct: 2221 LDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRED 2280

Query: 2281 TNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLV 2340
            TNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLV
Sbjct: 2281 TNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLV 2340

Query: 2341 GVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTD 2400
            GVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTD
Sbjct: 2341 GVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTD 2400

Query: 2401 TQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNM 2460
            TQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNM
Sbjct: 2401 TQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNM 2460

Query: 2461 FIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEI 2520
            FIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEI
Sbjct: 2461 FIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEI 2520

Query: 2521 EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE 2580
            EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE
Sbjct: 2521 EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE 2580

Query: 2581 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT 2640
            VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT
Sbjct: 2581 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT 2640

Query: 2641 EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSP 2700
            EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSP
Sbjct: 2641 EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSP 2700

Query: 2701 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI 2760
            PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI
Sbjct: 2701 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI 2760

Query: 2761 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA 2820
            PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA
Sbjct: 2761 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA 2820

Query: 2821 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI 2880
            EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI
Sbjct: 2821 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI 2880

Query: 2881 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR 2940
            GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR
Sbjct: 2881 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR 2940

Query: 2941 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW 3000
            DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW
Sbjct: 2941 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW 3000

Query: 3001 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG 3060
            IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG
Sbjct: 3001 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG 3060

Query: 3061 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120
            STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA
Sbjct: 3061 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120

Query: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180
            QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN
Sbjct: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180

Query: 3181 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL 3240
            EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL
Sbjct: 3181 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL 3240

Query: 3241 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA 3300
            SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA
Sbjct: 3241 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA 3300

Query: 3301 EWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDS 3360
            EWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDS
Sbjct: 3301 EWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDS 3360

Query: 3361 LEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKA 3420
            LEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKA
Sbjct: 3361 LEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKA 3420

Query: 3421 FGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVK 3480
            FGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVK
Sbjct: 3421 FGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVK 3480

Query: 3481 EGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMT 3540
            EGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMT
Sbjct: 3481 EGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMT 3540

Query: 3541 NEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGW 3600
            NEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGW
Sbjct: 3541 NEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGW 3600

Query: 3601 NIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILN 3660
            NIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILN
Sbjct: 3601 NIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILN 3660

Query: 3661 KFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQ 3720
            KFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQ
Sbjct: 3661 KFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQ 3720

Query: 3721 SETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQS 3780
            SETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQS
Sbjct: 3721 SETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQS 3780

Query: 3781 MNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKS 3840
            MNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKS
Sbjct: 3781 MNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKS 3840

Query: 3841 YPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPI 3900
            YPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPI
Sbjct: 3841 YPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPI 3900

Query: 3901 DLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLK 3960
            DLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLK
Sbjct: 3901 DLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLK 3960

Query: 3961 PCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLC 4020
            PCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLC
Sbjct: 3961 PCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLC 4020

Query: 4021 QLNS 4024
            QLNS
Sbjct: 4021 QLNS 4024


>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
          Length = 4116

 Score = 4036 bits (10466), Expect = 0.0
 Identities = 2071/3957 (52%), Positives = 2724/3957 (68%), Gaps = 110/3957 (2%)

Query: 129  VNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPMEDSWLEHV 188
            ++V++QQ+ +++S         KP+    E D+ RYYYY+ +GI  D +AP E   +  +
Sbjct: 209  LDVMLQQEMEMESKEK------KPS----ESDLERYYYYLTNGIRKDMIAPEEGEVMVRI 258

Query: 189  LDLVPQHLKV---FTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKT--DELP 243
              L+   L         +V L  E   DY  S+ KSIVD++L DP E+   K+   + +P
Sbjct: 259  SKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKSIVDYILMDPMER---KRLFIESIP 315

Query: 244  AHRAEMEI-LPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEFHN 302
                +  I  P PW   + +A  +  +HL+ +NP ML + +LW   F+ LR V   E   
Sbjct: 316  RLFPQRVIRAPVPWHSVYRSAKKWNEEHLHTVNPMMLRLKELWFAEFRDLRFVRTAEILA 375

Query: 303  CQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKK----KQLPTGDSSAKLE 358
             +  L+   F ++I +H   A +TLL  W P    ++    +           DSS  +E
Sbjct: 376  GKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLFTSRKEHWIHFAPKSNYDSSRNIE 435

Query: 359  SFFNCAAALMTLQLQDLTLVSMQDFTDL---------IAQPPDSVRAFEHPGFIMRLILD 409
             +F   A+ M+LQL++L + S++D   L           +P   ++ F     +++L + 
Sbjct: 436  EYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGNDFKEPYQEMKFFIPQLIMIKLEVS 495

Query: 410  NDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVE-------------TKLYSKWESKSK 456
               I F P      ++  + +  +IK  + +P+++              +   K     +
Sbjct: 496  EPIIVFNPSFDGCWELIRDSFLEIIKNSNGIPKLKYIPLKFSFTAAAADRQCVKAAEPGE 555

Query: 457  P------TTLKPI----ILNEIVDAHKEKIKE-------VIMKESVAPTEHLRLYDKYDF 499
            P      T +  +    +L   V+A ++ + +       V  K  V P ++L +Y KY  
Sbjct: 556  PSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQVGPCKYLNVYKKYVD 615

Query: 500  LITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRA 559
            L+   AE+++  FL ENH  +  + +I   +K   EI   +I T+ L MF +    L   
Sbjct: 616  LLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNI-TVPLAMFCLDATALNHD 674

Query: 560  LVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEV 619
            L +RA  +   L+      +++ NT +C+++  IA+K    P NT EL+ +  +++K   
Sbjct: 675  LCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA 734

Query: 620  TDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIE 679
              + +L ++L D+   L FL++Y     AD+           ++ +IF+  R ++  K +
Sbjct: 735  VTVFKLRRQLRDASERLEFLMDY-----ADLPY---------QIEDIFDNSRNLLLHKRD 780

Query: 680  QYQEGLKLRCERFVEELESYAKQSEEF--YSFGDLQDVQRYLKKAQILNGKLDLAADKIE 737
            Q +  L  RC  F   LE Y ++ E F        ++++  ++K   L+  L+ A  + E
Sbjct: 781  QAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFE 840

Query: 738  QFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVE 797
              N EEE      S YP  + +     PY +L+ TA EFS     W  GP   +N +Q+ 
Sbjct: 841  LINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIA 900

Query: 798  ADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAM 857
             +IGN WR  YKL KT  D P    + + V+ K++ FKQ+IP++ + CNPG++ RHW+ +
Sbjct: 901  EEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQI 960

Query: 858  SAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEF 917
            S IVGY ++P++ + +S+ L+     ++++ E I  AASKEYSLEK +++M  +W  V F
Sbjct: 961  SEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTF 1020

Query: 918  VIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEIL 977
                YR+T T IL ++D+IQMLLDDH+IKTQTM GSPFIKP E + R+WE KL+ +Q+ L
Sbjct: 1021 SFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNL 1080

Query: 978  DEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTID 1037
            D WLK QATWLYLEPIFSS DI++QMPEEGR+F  VD  W+ +M   ++D  +L      
Sbjct: 1081 DAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQP 1140

Query: 1038 RMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLK 1097
            RM E+L+++N LLE I KGLN+YLEKKRLFFPRFFFLSNDELLEILSETKDP RVQPHLK
Sbjct: 1141 RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLK 1200

Query: 1098 KCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK 1157
            KCFEGIAK+EFT+ L+I  M SSE E V  I+ I  A A+G VEKWL ++E++M+ S+ +
Sbjct: 1201 KCFEGIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMRE 1260

Query: 1158 VTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQI 1217
            V G    AY K  R +WV  WPGQ V+CVS IFWT+EV  A  +    L  +LK  N QI
Sbjct: 1261 VIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQA--LAENTLLDFLKKSNDQI 1318

Query: 1218 DDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQEN 1277
              IV LVRGKLS   R+TLGAL V+DVHARDV++ L +  +SD +DF+W+SQLRYYW   
Sbjct: 1319 AQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAK 1378

Query: 1278 HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTET 1337
             ++ ++I     YGYEYLGNSPRLVITPLTDRCYRTL GAL L+LGGAPEGPAGTGKTET
Sbjct: 1379 DVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTET 1438

Query: 1338 TKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQI 1397
            TKDLAKA+AKQCVVFNCSDGLDY A+GKFFKGL   GAWACFDEFNRI++EVLSVVAQQI
Sbjct: 1439 TKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQI 1498

Query: 1398 LTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPD 1457
            L+IQ+ I       +FEGTEL L+PTCAVFITMNPGYAGR+ELPDNLKALFRTVAMMVPD
Sbjct: 1499 LSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPD 1558

Query: 1458 YAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL 1517
            YA+I EI LYS GF+ +R L+ KIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL
Sbjct: 1559 YALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL 1618

Query: 1518 KYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNC 1577
            KYP ENE +LLLR+++DVNL KFL+ D+PLF+GI SDLFPGV LPKPDY   L  + DN 
Sbjct: 1619 KYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNI 1678

Query: 1578 ASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEE 1637
              M LQ   +F  KI+Q+YEMM+VRHG+MIVG+P GGKTSAY+VLA AL D+     MEE
Sbjct: 1679 KKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEE 1738

Query: 1638 NKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDA 1697
              V+  ++NPK++TMGQLYG FD VSHEW DGVLA +FR  ASS++ DRKW+IFDGPVDA
Sbjct: 1739 FAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDA 1798

Query: 1698 VWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHML 1757
            +WIENMNTVLDDNKKLCLMSGEIIQM+ +M+LIFEP DLE ASPATVSRCGMIYMEPH L
Sbjct: 1799 IWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQL 1858

Query: 1758 GWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLM 1817
            GW+PL  S+++ LP+S++   KE +  +F  +V   +EF R H K +  TS  +L  S+M
Sbjct: 1859 GWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMM 1918

Query: 1818 NLIDCFMDDF----ADEVKLKE-RNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKI 1872
             L    +D+      +E++L E  + ++ +  L+G+FLFSL+W+V  +   D R KF+  
Sbjct: 1919 RLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVF 1978

Query: 1873 LRELMESPISDRTR-NTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIK 1931
             R L+     +  R  + KL               FPE+G+IYD+ F+ +  G WE W +
Sbjct: 1979 FRNLIMGMDDNHPRPKSVKLTKNN----------IFPERGSIYDFYFIKQASGHWETWTQ 2028

Query: 1932 KL-KEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFL 1990
             + KE   +P     +E+I+PT++T R S  ++    H+ P +FVGPTGTGKS    NFL
Sbjct: 2029 YITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFL 2088

Query: 1991 LNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPA 2050
            L+ L K  Y P  INFSA+T+A QTQ+I+MSKLD+RRKG+FGPP+GK+ VVFVDD+NMPA
Sbjct: 2089 LH-LPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA 2147

Query: 2051 REVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHF 2110
            +EVYGAQPPIELLRQW+DH  W+D KD + + +VD+ ++ AMGPPGGGRN +T R+ RH 
Sbjct: 2148 KEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHL 2207

Query: 2111 NIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPT 2170
            NII+IN F D  +  IFS I+ WH      F   FL     +V  T T+Y++A++N LPT
Sbjct: 2208 NIISINAFEDDILTKIFSSIVDWHFG--KGFDVMFLRYGKMLVQATKTIYRDAVENFLPT 2265

Query: 2171 PAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLI 2230
            P+KSHY+FNLRDFSRVIQGV L      +  E   RLW+HEV RV+YDRL+D  DR    
Sbjct: 2266 PSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFF 2325

Query: 2231 NYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVD 2290
            N ++E   N   +   ++   +     G +  D++RSL F D+  P+ +   Y EI D+ 
Sbjct: 2326 NMVKETTSNCFKQTIEKVL--IHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLK 2383

Query: 2291 NLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSV 2350
             L +++E +LEE+NNISK PM+LV+FRFAIEHISRI R+LKQ + H LLVG+GGSGRQS 
Sbjct: 2384 QLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSA 2443

Query: 2351 TRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLE 2410
             +L+  M  Y ++Q+EI+K Y   +W EDLK I+ +        VFLF D QIK+ESF+E
Sbjct: 2444 AKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVE 2503

Query: 2411 DVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLH 2470
            D++ LLN G++PN+F  DEK +I +KM+     R + ++ + +P++++N FI+   +++ 
Sbjct: 2504 DINMLLNTGDVPNIFPADEKADIVEKMQ--TAARTQGEKVEVTPLSMYNFFIERVINKIS 2561

Query: 2471 VVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGC 2530
              LAMSPIGDAFRNRLR FP+L+NCCTIDWFQSWP DAL+ VA++FLE++E+ + IR   
Sbjct: 2562 FSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEV 2621

Query: 2531 IDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEV 2590
            + MCK F  S   LS  ++ +L+R+NYVTPTSYLELI TFK LL  KR EV  M+ RY  
Sbjct: 2622 VSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLT 2681

Query: 2591 GLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETI 2650
            GL+KLD A+SQVA MQ EL AL PQL + S+E  +MM+ IE E+ E    + +V+ADE  
Sbjct: 2682 GLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKE 2741

Query: 2651 ANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEA 2710
            AN  A  ++ IK+EC+ DLA A+P LE+ALAALDTL   DI++VKSM++PP  VKLVME+
Sbjct: 2742 ANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMES 2801

Query: 2711 ICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRK 2770
            ICI+KG+K ++ PDP+GSGK IED+WG +K++LGD++FL+SL  YDKDNIPP  M  IR+
Sbjct: 2802 ICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRE 2861

Query: 2771 NYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDG 2830
             +I +P+F P  I+N S+A EGLCKWV AM+ YD+VAK+VAPK+ +L  AEG+L   M  
Sbjct: 2862 RFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQK 2921

Query: 2831 LRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRW 2890
            L +K+A LK V D+L  L D  E    KK DLE  +++CS+KL RAE+LI GLGGEK RW
Sbjct: 2922 LNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRW 2981

Query: 2891 SHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSDDCSL 2950
            +  A +LG  Y NLTGD+L+SSG VAYLGAFT  YR     +W   CK + IP   D SL
Sbjct: 2982 TEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSL 3041

Query: 2951 MGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSL 3010
              TLG+ + IR W IAGLP DSFSIDNGII+ N+RRW LMIDP  QANKWIKNMEKAN L
Sbjct: 3042 SHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKL 3101

Query: 3011 YVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDST 3070
             VIK S+ +Y+R LEN +Q GTPVL+EN+GEELD  +EP+LLK TFKQ G   +RLG++ 
Sbjct: 3102 AVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENI 3161

Query: 3071 IEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEK 3130
            IEY+ DF+ YITT+LRNPHYLPE +VKV LLNFMITP G+QDQLLGIV A+E+P+LEE+K
Sbjct: 3162 IEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKK 3221

Query: 3131 QALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAE 3190
              LI++ A+NK+ LKEIEDKILEVLS S+GNILEDETAIK+LSSSK L+ EIS+KQ+VA 
Sbjct: 3222 NQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVAS 3281

Query: 3191 ETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEI 3250
             TE +ID TRMGY+P+A+HS+ +FF ++DLANIEPMYQYSLTWFINL++ S+ +S KSE 
Sbjct: 3282 MTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEE 3341

Query: 3251 LAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGI 3310
            L  R++ + DHFT S+Y NVCRSLFEKDKLLFS  LTI ++  ++ I +  W FLLTGGI
Sbjct: 3342 LNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGI 3401

Query: 3311 GLDNPYANLC-TWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFP 3369
             LDNPY N    WL +K+W EI R   LP    +     +    WK +YDS  PH E  P
Sbjct: 3402 ALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLP 3461

Query: 3370 EEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAP 3429
              W+  +   ++M+I+RCLRPDK++P ++EFI   +G+ +IE P FDL  ++ DS+CCAP
Sbjct: 3462 GSWK-FSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAP 3520

Query: 3430 LIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQN 3489
            LIFVLSP ADPMA LLKFADD G GG++  ++SLGQGQGPIA KM+  A+K+GTWVVLQN
Sbjct: 3521 LIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQN 3580

Query: 3490 CHLATSWMPTLEKVCEE-LSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLR 3548
            CHLA SWMPTLEK+CEE + PEST+  FR+WLTSYPS  FPVS+LQNG+KMTNE PKGLR
Sbjct: 3581 CHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLR 3640

Query: 3549 ANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNE 3608
            AN++RSYL DPISDP FF SC K   ++K+L+GLCFFHA+VQERR FGPLGWNIPYEFNE
Sbjct: 3641 ANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNE 3700

Query: 3609 TDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELV 3668
            +DLRIS+ Q+ MFLN Y+E+P++AL Y+TGECNYGGRVTDD DRR L S+L+ F+  E +
Sbjct: 3701 SDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKE-I 3759

Query: 3669 ENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFD 3728
            E   Y       Y++PP G ++SYI+Y + LP+T  PE+FG++ NADITKD  ET  LF+
Sbjct: 3760 EEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFE 3819

Query: 3729 NILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQE 3788
             +LLT  R +G   KS  EVV E+A DIL KLP +FD+E  M+ YP  Y +SMNTVL QE
Sbjct: 3820 GVLLTLPRQSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQE 3879

Query: 3789 MGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLG 3848
            + RFN+L K +R S +N+ +AIKG  +MS++LEEV +S+L  K+P MW  KSYPSLKPLG
Sbjct: 3880 LIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLG 3939

Query: 3849 SYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYE 3908
             YV D LARL F Q+W + GPP VFW+SGF+FTQ+FLTG  QNYARKYTIPID +GF++E
Sbjct: 3940 GYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFE 3999

Query: 3909 VM-EDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADI 3967
            V  ++   ++ PEDG +I GLFL+GA W+RK  ++ ES PKILYD +P++WLKP + A  
Sbjct: 4000 VTPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMF 4059

Query: 3968 PKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLNS 4024
              +  YV P+YKTS RRG LSTTGHSTN+V+++ LP+D P++HWI RGVA LCQL++
Sbjct: 4060 LHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN 4116


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 3158 bits (8187), Expect = 0.0
 Identities = 1680/3685 (45%), Positives = 2353/3685 (63%), Gaps = 111/3685 (3%)

Query: 385  DLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVE 444
            DLI  P    R  ++P FIM L+LD+  + +   L  +    LN++D  I A   VP++E
Sbjct: 645  DLINSP---YRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLE 701

Query: 445  TKLYSKWESKSKPTTLKPIILNE-IVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITR 503
             KL  +    S    L+ + L+E +V+  +  I   + K  +    + + Y KY  L   
Sbjct: 702  -KLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN 760

Query: 504  KAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKR 563
                 +  +  +    +++ + +  + +  E +  +   +I +G F ++ + + ++L K+
Sbjct: 761  DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK 820

Query: 564  ADIICGKLLAKMFRD-HQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDM 622
               +   +L  + ++ H+EV++ +C+EF  I+ K    P +  EL E++ +++ +    +
Sbjct: 821  RKALATSVLDILAKNLHKEVDS-ICEEFRSISRKIYEKPNSIEELAELREWMKGIPER-L 878

Query: 623  IELEQRLVDSKNCLAFLIEYV-NFSPADMRLNNSVFQWYGR-MGEIFEEHRKIIKEKIEQ 680
            + LE+R+V   +    + E++ N S  D         W  + +G+I    ++ ++++ E+
Sbjct: 879  VGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDE-EK 937

Query: 681  YQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFN 740
            +++   +    F E+LE        F    ++        + + +  +L         +N
Sbjct: 938  FRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYN 997

Query: 741  AEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADI 800
              E  F    + Y +  ++     PYL L+ TA ++     +W   P   ++ +Q+E ++
Sbjct: 998  NRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNV 1057

Query: 801  GNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAI 860
               ++ ++K  K F D P    +   +R+++E+FK +IPLIQ + NPG+R RHWE +S  
Sbjct: 1058 VEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQ 1117

Query: 861  VGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIH 920
            +   ++P  + T +  L+MNL+ +I+    ++E A KEY++E+A++KM  EW  + F + 
Sbjct: 1118 ININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVL 1177

Query: 921  SYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEW 980
             Y+ T T+IL S DE   LLDDHI+ TQ M  SP+ KP+E+++  WE KL L QE+L+EW
Sbjct: 1178 PYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEW 1237

Query: 981  LKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML 1040
            L  Q +WLYLEPIFSS DI  Q+P E +R+  +++ W+ IM++  +++ V+ V +  RML
Sbjct: 1238 LNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRML 1297

Query: 1041 ERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCF 1100
            + L+  N++L+L+ KGL+EYLE KR  FPRF+FLS+DELLEILS+TKDPT VQPHL+KCF
Sbjct: 1298 DSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCF 1357

Query: 1101 EGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTG 1160
            E IA++ F E L+ITHM S+EGE V+L   I  +     VE WL E+ER M  S+H +  
Sbjct: 1358 ENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSS---NVEDWLREVERSMKASVHDIIE 1414

Query: 1161 DATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDI 1220
             A  AY    R  WV +WPGQ  +   Q +WT EV  A+  G    + + + C +Q+ D+
Sbjct: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLC-QQLSDL 1473

Query: 1221 VTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLE 1280
            V LVRGKLS   R  L AL+V++VHA+DV+S L+++N+   +DF+W+SQLRYYW  N L 
Sbjct: 1474 VALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLY 1533

Query: 1281 TKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKD 1340
             + +NA   YGYEYLGNS RLVITPLTDRCY TL GALHL  GGAP GPAGTGKTETTKD
Sbjct: 1534 IRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKD 1593

Query: 1341 LAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTI 1400
            L KA+A Q VVFNCSD LD++A+GKFFKGL S GAWACFDEFNRID+EVLSVVAQQI TI
Sbjct: 1594 LGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTI 1653

Query: 1401 QRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAM 1460
            Q+      +  MFEG E+ L P+CAVFITMNPGYAGR+ELPDNLKALFR VAMMVPDYAM
Sbjct: 1654 QKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAM 1713

Query: 1461 IAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYP 1520
            I EI LYS GF  A  L+ KI  T++L SEQLSSQ HYD+GMRAVK+V++AAGNLK + P
Sbjct: 1714 ITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENP 1773

Query: 1521 NENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASM 1580
            + NEE++ LR+I DVN+PKFL  DL LF GI SDLFP +K    DY  L  AI++ C + 
Sbjct: 1774 SMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNS 1833

Query: 1581 NLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDI-----CEKGLM 1635
            NL+    F  K +Q+YE  +VRHG M+VG    GK++ YRVLA A+  +        G+ 
Sbjct: 1834 NLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMY 1893

Query: 1636 EENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPV 1695
            E   V   VLNPKS+TMGQLYG+FD ++HEW+DG+ +   RA A +   ++KW +FDGPV
Sbjct: 1894 EA--VNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPV 1951

Query: 1696 DAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPH 1755
            DA+WIENMNTVLDDNKKLCL SGEII+++  M ++FE  DL VASPATVSRCGM+Y+EP 
Sbjct: 1952 DAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPS 2011

Query: 1756 MLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRS 1815
            +LG  P +  W+  LP  +   ++ F   LF   +  S+ F+R   KE+  +++ NL  S
Sbjct: 2012 ILGLMPFIECWLRKLPPLLKPYEEHF-KALFVSFLEESISFVRSSVKEVIASTNCNLTMS 2070

Query: 1816 LMNLIDCFMDDFADEVKLKERNDRETYSLLEGI---FLFSLIWSVGASCTDDDRLKFNKI 1872
            L+ L+DCF   F     LK+    +   ++E I   F+FSLIWSVGA+     R  F+  
Sbjct: 2071 LLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHW 2130

Query: 1873 LRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIG-------- 1924
            LR  ME+                     + LT+ FPE+G ++DY+    GI         
Sbjct: 2131 LRLKMEN---------------------EQLTLLFPEEGLVFDYRLEDAGISGTNDSEDE 2169

Query: 1925 ----KWEPWIKKLKEAPPIPK--DVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978
                K   W+K +  + P     D  +  IIVPT+DT++ S L+++L T++KP + +GPT
Sbjct: 2170 EEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPT 2229

Query: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038
            GTGK++ I++ LL  L  + Y    + FSA+T+A QTQ+ + SKLDKRRKGVFGPPLG+ 
Sbjct: 2230 GTGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRN 2288

Query: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIK-LVDIQIMCAMGPPGG 2097
             + F+DD+NMPA E YGAQPPIELLRQW+DH  WYD K     K LVDI  +CAMGPPGG
Sbjct: 2289 FIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGG 2348

Query: 2098 GRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHL-----EICYKF----PDEFLDL 2148
            GRN VTPR MRHFN ++  E  + S   IFS IL   L     E  Y+            
Sbjct: 2349 GRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHF 2408

Query: 2149 TTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLW 2208
            T  +V  T+ +Y      LLPTPAKSHY FNLRD S+V QG+ ++ P   E    + RLW
Sbjct: 2409 TEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLW 2468

Query: 2209 VHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSL 2268
             HE  RV+ DRL++  DRSW      ++L+  M E +   F ++             + +
Sbjct: 2469 YHENCRVFRDRLVNEEDRSWF----DQLLKRCM-EQWEVTFNKVC----------PFQPI 2513

Query: 2269 MFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISR 2328
            ++ DF  P  +  +Y  I     +  ++E ++E+YN I+   + LVLF  A+ HI RISR
Sbjct: 2514 LYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISR 2573

Query: 2329 ILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCA 2388
             L+Q   +ALL+GVGGSGR S+TRLA+HMA+Y  FQ+E+SK Y  +EW +D+K +L K  
Sbjct: 2574 TLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAG 2633

Query: 2389 EGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTK 2448
               +   FLF+DTQIK ESFLED++N+LN+G+IPNL+  DE+ +I   MR   +++    
Sbjct: 2634 LQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQG--- 2690

Query: 2449 QTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDA 2508
                +   L   +    RS +H+VL MSPIG+ FR RLR+FP+LVNCCTIDWF  WP +A
Sbjct: 2691 -LQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEA 2749

Query: 2509 LQAVASRFLEEI---EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLE 2565
            L++VA+ FL EI   E S+E   G I +C   H S       +  EL R+NYVTP SYLE
Sbjct: 2750 LKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLE 2809

Query: 2566 LISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDE 2625
            L+  F +L+ +K+ E+   K R + GL+KL   S  VA MQ +LE++HP L+ A+K+   
Sbjct: 2810 LLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTML 2869

Query: 2626 MMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDT 2685
             M  I+ ++    +T   V+ +E  ANE+A  ++AI D+   DL  ALP L++ALA+L  
Sbjct: 2870 TMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRN 2929

Query: 2686 LTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGD 2745
            L   D+T V++M+ PP GVKLV+EA+CI+KGIK  K+P     G K++D+W P K LL D
Sbjct: 2930 LNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEK-PGTKVDDYWEPGKGLLQD 2988

Query: 2746 M-RFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804
               FL+SL ++DKDNI    +  I+  YI N +F P  I   S A   +C+WV AM  Y 
Sbjct: 2989 PGHFLESLFKFDKDNIGDVVIKAIQP-YIDNEEFQPATIAKVSKACTSICQWVRAMHKYH 3047

Query: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864
             VAK V PK+  L  A+ +L +    L + +  L+EV+D +A +Q        KK +LE 
Sbjct: 3048 FVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELEL 3107

Query: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924
            + + C ++L RA +LI GL  EK RW  T   L  +  N++GD+L+++G VAYLG FT  
Sbjct: 3108 KCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQ 3167

Query: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984
            YR      W    +  ++P + + +L+GTLG  V IR+W IAGLP+D+ S++NG+I   +
Sbjct: 3168 YRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFS 3227

Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044
            +RW   IDPQSQANKWIKNMEK N L V KLS+ D++R++EN I+FG P LLENVGEELD
Sbjct: 3228 QRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELD 3287

Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104
            P LEP+LLKQT+KQ G+T ++LGD+ I Y  DFR YITTKL NPHY PE S K+TL+NF 
Sbjct: 3288 PALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFT 3347

Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164
            ++P G++DQLLG VVA+ERPDLEE K  LI+  A+ +++LK+IED+IL  LSSSEGN ++
Sbjct: 3348 LSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVD 3407

Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224
            D   IK+L +SK  A EI  K  +AE+TEK ID TRM Y P+AI + ILFF ++DLAN++
Sbjct: 3408 DMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVD 3467

Query: 3225 PMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSF 3284
            PMYQYSL WF+N+F+  I NSE+++ L KR+  +  + TYSLY NVCRSLFEK KL+F+F
Sbjct: 3468 PMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAF 3527

Query: 3285 CLTINLLLHERAINKAEWRFLLTGG---IGLDNPYANLCTWLPQKSWDEICRLDDLPAFK 3341
             L + ++++E  IN++EWR+LL+GG   I  +NP  +   WL  ++W +I  L +LP F 
Sbjct: 3528 LLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPD---WLSDRAWRDILALSNLPTFS 3584

Query: 3342 TIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFI 3401
            +   +F++    ++ ++DSLEPH E  P  W+   ++FQ++L++RCLR DKV   +Q+F+
Sbjct: 3585 SFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFV 3644

Query: 3402 INRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSL 3461
               L   FIEP   +L+  F DSN   PLIFVLSPG DP A L KFA++  +   KLS++
Sbjct: 3645 ATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAI 3703

Query: 3462 SLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLT 3521
            SLGQGQGP A  M+  +++ G WV  QNCHLA SWMP LE++ E ++P+  H DFR+WLT
Sbjct: 3704 SLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLT 3763

Query: 3522 SYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYG 3581
            S PS  FPVS+LQNG KMT E P+G+RAN+++SY        +F  SC K  EFK LL  
Sbjct: 3764 SLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSY---SSLGEDFLNSCHKVMEFKSLLLS 3820

Query: 3582 LCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECN 3641
            LC FH    ERRKFGPLG+NIPYEF + DLRI + QL MFL++Y+++PY+ L+Y  GE N
Sbjct: 3821 LCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEIN 3880

Query: 3642 YGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYF-VPPSGDHKSYIEYTKTLP 3700
            YGGRVTDDWDRR + +IL  F+NP+++ + ++ + +SGIY  +PP+ D   Y+ Y K+LP
Sbjct: 3881 YGGRVTDDWDRRCIMNILEDFYNPDVL-SPEHSYSASGIYHQIPPTYDLHGYLSYIKSLP 3939

Query: 3701 LTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKL 3760
            L   PEIFG++ NA+IT  Q+ET  L   I+  Q +S+ AG++  +E+V +V  +IL K+
Sbjct: 3940 LNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKV 3999

Query: 3761 PNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDL 3820
            P   +++  M +YP  Y +SMNTVLVQE+ R+N+LL+ I  +  ++ KA+KGL VMS+ L
Sbjct: 4000 PEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQL 4059

Query: 3821 EEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFF 3880
            E + +S+ N  +PE+W  K+YPSLKPL S+V D L RL FLQ W + G P VFW+SGFFF
Sbjct: 4060 ELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFF 4119

Query: 3881 TQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRK 3938
             QAFLTG  QN+ARK+ I ID + FD++VM +   E    P+ G +IHGLFL+GA W+ +
Sbjct: 4120 PQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPE 4179

Query: 3939 IKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVI 3998
              +LAES PK LY  + V+WL P        +  Y+ P+YKT  R G LSTTGHSTN+VI
Sbjct: 4180 AFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVI 4239

Query: 3999 AMTLPSDQPKEHWIGRGVALLCQLN 4023
            A+ +P+ QP+ HWI RGVAL+C L+
Sbjct: 4240 AVEIPTHQPQRHWIKRGVALICALD 4264


>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
          Length = 4158

 Score = 2631 bits (6819), Expect = 0.0
 Identities = 1491/3738 (39%), Positives = 2180/3738 (58%), Gaps = 205/3738 (5%)

Query: 400  PGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLY----------S 449
            P F+  L+L   ++ FEP L D++D  L   +     V  VP +    Y          +
Sbjct: 511  PMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINN 570

Query: 450  KWESKSKPTTLK-PIILNEIVDAHK--EKIKEVIMKESVAPTEHLRLYDKYDFLITRKAE 506
            K E K+  T      +  +  + H    +IKE I     +   +   ++K+         
Sbjct: 571  KLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQIFFKENES 630

Query: 507  RDVDNFLAENHSYEKIIDEICKYQKLIEE-IQYTSIKTIRLGMFEMHCEELIRALVKRAD 565
             D+     +        +++ KY K  ++ +     + + L + +     L+R  +  + 
Sbjct: 631  LDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTR---LLREKLIPSP 687

Query: 566  IICGKLLAKMF-RDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIE 624
            + C ++L  M  R  ++    +  E +    K    P  T E +    ++ +++     E
Sbjct: 688  LRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQ-----E 742

Query: 625  LEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEG 684
              + L D  N +  +  Y       +      F  +  M       R  I + +   +  
Sbjct: 743  RIESLEDEGNIVTQM--YKLMEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKSVGDRESS 800

Query: 685  LKLRCERFVEELESYAKQSEEFYSFGD---LQDVQRYLKKAQ-ILNGKLDLAAD---KIE 737
            +K  C     +LE    +  E         + D+     K + ILN    + AD   +  
Sbjct: 801  IKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAF 860

Query: 738  QFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVE 797
            Q+ + ++ F    S +   +++   L     L+++  E+    + W +  +  ++P+ + 
Sbjct: 861  QYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLN 920

Query: 798  ADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAM 857
              +  Y + + +LEK    +    ++  +++ KVE  K+ +P+I  + NP L+ RHW A+
Sbjct: 921  GQVSKYAKFVTQLEKGLPPN----SVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAI 976

Query: 858  SAIVGYPLQPSD-DSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVE 916
               V   L  ++   T+     +++  +    + IS  AS E +LE  ++K+   W   E
Sbjct: 977  EQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTE 1036

Query: 917  FVIHSYRET-GTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQE 975
            FVI  +R++   FIL   D+IQ+LLDD  I   T+  S ++ P + ++ EW+ +L L  +
Sbjct: 1037 FVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQ 1096

Query: 976  ILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVT 1035
             L+EWL  Q  WLYLE IF++PDI  Q+P E + F  VDK+W++IMR V +  + L   T
Sbjct: 1097 TLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAAT 1156

Query: 1036 IDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPH 1095
               +LE  + +N LL+ I K L  YLE KR+ FPRF+FLSNDELLEIL++T++P  VQPH
Sbjct: 1157 QPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPH 1216

Query: 1096 LKKCFEGIAKVEFT-------------------ETLDITHMKSSEGEVVELIEIISTAKA 1136
            L+KCF+ I+K+EF                     T DI  M S EGE V L + +   KA
Sbjct: 1217 LRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGL---KA 1273

Query: 1137 RGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWV-RDWPGQTVLCVSQIFWTKEV 1195
            RG VE+WL ++E  M  S+ ++   A   Y    R +WV    P Q +L VSQI W +++
Sbjct: 1274 RGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDL 1333

Query: 1196 ----QTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLS 1251
                +T     I+AL+ + K    +++ +  +V+G L   +R  L AL+ +DVHARD+++
Sbjct: 1334 TECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVT 1393

Query: 1252 SLVKKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDR 1309
             LV+  +     F+W  QLRYYW  +  +   +M  +   YGYEYLG  PRLVITPLTDR
Sbjct: 1394 ELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDR 1453

Query: 1310 CYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKG 1369
            CY  L GAL L LGGAP GPAGTGKTETTKDLAKA+A QCVVFNCSDGLDY  +G+FF G
Sbjct: 1454 CYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSG 1513

Query: 1370 LLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFIT 1429
            L   GAW CFDEFNRID+EVLSV+AQQ++TI+    A     MFEG E+KL  TCA FIT
Sbjct: 1514 LAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFIT 1573

Query: 1430 MNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCS 1489
            MNPGYAGR+ELPDNLKALFR  AMMVP+YA+IAE++LYS GF +++ L+ K+   Y+LCS
Sbjct: 1574 MNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCS 1633

Query: 1490 EQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFE 1549
            EQLS Q HYD+GMRAVKSVL  AG+LK + P+ NE+++L+R++ D NLPKFL+ D  LF 
Sbjct: 1634 EQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFS 1693

Query: 1550 GITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVG 1609
            GI SDLFPGV++P+ DY  L + I D     NLQ       K++Q YE M+VRHG M+VG
Sbjct: 1694 GIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVG 1753

Query: 1610 EPFGGKTSAYRVLAGALNDICEKGLMEE--NKVQITVLNPKSVTMGQLYGQFDSVSHEWS 1667
               GGKT+ YR+LA  L ++ + G+       V+  VLNPKS+TMG+LYG+ ++++ EW 
Sbjct: 1754 PTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWK 1813

Query: 1668 DGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQM 1727
            DG++A+S RA  +  + D KW+I DGPVDA+WIENMNTVLDDNK LCL + E I+++PQ+
Sbjct: 1814 DGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQI 1873

Query: 1728 NLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFD 1787
            +++FE  DL VASPATVSRCGM++++P  L W P + +W+  +   ++   +E+I+ LF 
Sbjct: 1874 HMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQ 1933

Query: 1788 RMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEG 1847
            R V   + FI K   +  P  D + V +L  L++  +    D V L     +    L + 
Sbjct: 1934 RYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILG-KDGVNLAMEQTKLNTILCQ- 1991

Query: 1848 IFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPF 1907
             F+F  +WS+G + T++    F+  +R   +     R  N+  L S              
Sbjct: 1992 TFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWS-------------- 2037

Query: 1908 PEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTT 1967
                      F T+ +  WE  I   K      +DV F E++VPT DT+RY  LME L  
Sbjct: 2038 ------IHMDFDTKRLDPWERIIPTFK----YNRDVPFFEMLVPTTDTVRYGYLMEKLLA 2087

Query: 1968 HQKPSIFVGPTGTGKSVYITNFLLNQLNKEI-YKPLLINFSAQTTAAQTQNIVMSKLDKR 2026
             +   +F G TG GKSV I   LLN++ +   Y P+ +NFSAQT++A+TQ I+ SKL+++
Sbjct: 2088 VKHSVLFTGITGVGKSV-IAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERK 2146

Query: 2027 RKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDI 2086
            RK + G P  KR+V+FVDD+NMP  + YG+QPPIELLRQ+ D   +YD       ++ D+
Sbjct: 2147 RKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDV 2206

Query: 2087 QIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFL 2146
             I+ A  PPGGGRNPVTPR++RHF+++ +   S+ S+  IF  IL   L     FP    
Sbjct: 2207 TIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLS---DFPPAVK 2263

Query: 2147 DLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKR 2206
               + IV  ++ +Y +   +LLPTPAKSHY+FNLRD S+ +QG+    P T      I R
Sbjct: 2264 QTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFR 2323

Query: 2207 LWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLR 2266
            L+ HE  RV++DRL++N D+    +Y   IL     + F        F N  ++  D ++
Sbjct: 2324 LFCHECQRVFHDRLINNEDK----HYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIK 2379

Query: 2267 SLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRI 2326
                       + D  Y ++ D++    +++ +L++YN  + K + LV F+ AIEH+SRI
Sbjct: 2380 -------FGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRI 2432

Query: 2327 SRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRK 2386
            +R+++Q R +ALLVGVGG+G+QS+TRLAAH+  Y   Q+E+S+GY+   +HEDL+ + + 
Sbjct: 2433 ARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKM 2492

Query: 2387 CAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDK 2446
                +   VFLFTDTQI  E FLED++N+LN+GE+PNLF  DE +++      L   R +
Sbjct: 2493 AGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQV------LAATRPR 2546

Query: 2447 TKQ---TDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQS 2503
             K+   ++G+   +F  FI   R +LH+VL MSP+G+AFR+R R FP+LVNCCTIDWF  
Sbjct: 2547 AKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQ 2606

Query: 2504 WPEDALQAVASRFLEEIEM-SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTS 2562
            WP +AL +V+  F  +++  +EE+++    MC + H S   +++ ++ EL+R  Y TPTS
Sbjct: 2607 WPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTS 2666

Query: 2563 YLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKE 2622
            YLELI+ +  +L +KR +++  + R + GL KL   +  V  M+++L AL P L   S++
Sbjct: 2667 YLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSED 2726

Query: 2623 VDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAA 2682
            V+ +M  +  +     +    V+ DE  A  +A  ++AI D+   DL  ALP L++A  A
Sbjct: 2727 VEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKA 2786

Query: 2683 LDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRL 2742
            LD+L   DI+ ++    PP  V  VMEAI IL   K D               W  AK+L
Sbjct: 2787 LDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPD---------------WPSAKQL 2831

Query: 2743 LGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDS 2802
            LGD  FL+ L EYDK+NI P  +  ++K YI NPDFVPEK+   S A + +C WV AMD 
Sbjct: 2832 LGDSNFLKRLLEYDKENIKPQILAKLQK-YINNPDFVPEKVEKVSKACKSMCMWVRAMDL 2890

Query: 2803 YDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADL 2862
            Y +V K+V PK+ KL AA+ EL I M  LR+KQA L++V+D++  LQD  +    +K  L
Sbjct: 2891 YSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESL 2950

Query: 2863 ENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFT 2922
               + L   +L RA +L   L  E+ RW  +  +  +   N+TG++ I++  VAY GAFT
Sbjct: 2951 AKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFT 3010

Query: 2923 STYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIM 2982
            + YRQ+  + W   C+  +IP     SL+  LG+   IR WN  GLP D  S +NGI++ 
Sbjct: 3011 AQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVT 3070

Query: 2983 NARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEE 3042
              RRWPLMIDPQ QAN+WI+N E  + L +IKL++ +++R LEN I+ G PVLLE + E 
Sbjct: 3071 QGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKET 3130

Query: 3043 LDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLN 3102
            LDP LEP+LLKQ F  GG   IRLGDS I+Y  +FRFY+TTK+ NPHYLPE  +KVT++N
Sbjct: 3131 LDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIIN 3190

Query: 3103 FMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNI 3162
            F +T  G++DQLL  VV  E+P LEE++  LI++   +K QLK IE+KIL +L +SEGNI
Sbjct: 3191 FTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNI 3250

Query: 3163 LEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLAN 3222
            L++E  I  L  SK  +  I  + E AE TE+ I+  R  YRP+A   S+++F +A L+ 
Sbjct: 3251 LDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSE 3310

Query: 3223 IEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLF 3282
            I+PMYQYSL +F  LF  +IE S K+E L +RL +L +    + YVNV R LFE+ KL++
Sbjct: 3311 IDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIY 3370

Query: 3283 SFCLTINLLLHERAINKAEWRFLLTGGIGL--DNPYANLCTWLPQKSWDEICRLDD-LPA 3339
            SF L + ++  +  ++ AEW F L G  GL  + P      WLP  +W   C L++  P 
Sbjct: 3371 SFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPV 3430

Query: 3340 FKTIRRE------------------------FMRLKDGWKKVYDSLEPHHEVFPEEWEDK 3375
            F  + +                         + ++K   K +    E  H+   + W   
Sbjct: 3431 FHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQ---DPWSAG 3487

Query: 3376 ANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLS 3435
             + F ++++I+C + +KV+  L +F+I  LG+ FIE PP DL   + D +C  PL+F+LS
Sbjct: 3488 LSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILS 3547

Query: 3436 PGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATS 3495
             G+DPM A  +FA + GY   ++ S+SLGQGQGPIA KM++ A+K G WV LQNCHLA S
Sbjct: 3548 TGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVS 3606

Query: 3496 WMPTLEKVCEELS-PESTHPD-FRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIR 3553
            WM  +E++ +  + P+S   D FR++L+S PS  FPV+VLQN VK+TNE PKGLRANI R
Sbjct: 3607 WMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRR 3666

Query: 3554 SYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRI 3613
            ++       P FF      ++++++++G+CFFHA++QER+KFGPLGWNI YEFN++D   
Sbjct: 3667 AFTE---MTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDREC 3723

Query: 3614 SVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDY 3673
            ++  L ++  +  ++P++AL Y+TGE  YGGRVTD WD+R LR+IL +FF+PE +E  DY
Sbjct: 3724 ALLNLKLYCKE-GKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLE-EDY 3781

Query: 3674 KFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLT 3733
            K+  SGIYF P +   + + +Y + LPL   PEIFGM+ NA++     ET  L + IL  
Sbjct: 3782 KYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEV 3841

Query: 3734 QSRSA-GAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQ----SMNTVLVQE 3788
            Q RS+ G   KS+DE+V E+ + +  ++P   ++E A         Q    S+ TVL QE
Sbjct: 3842 QPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQE 3901

Query: 3789 MGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLG 3848
            + RFN LLK I  S   + KAI G  VMS ++E+V +S LN ++P +W   +YPSLKPLG
Sbjct: 3902 VDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLG 3961

Query: 3849 SYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYE 3908
            S+V D + R  F+  W + G P  +W+SGFFF Q FLTG  QN+ARKY +PID L F Y 
Sbjct: 3962 SWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYS 4021

Query: 3909 VME-----------------------DKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAES 3945
            V+                        D E    PEDGV +HG+F+D + W+ K   + ++
Sbjct: 4022 VIPTYRDQAAVIEAAKTVQFGQELPMDMELP-SPEDGVLVHGMFMDASRWDDKEMVIEDA 4080

Query: 3946 HPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSD 4005
             P  +   +PV+  +P +    P    Y  PLYKT  R G LSTTGHSTNFV+ + LPS 
Sbjct: 4081 LPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSK 4139

Query: 4006 QPKEHWIGRGVALLCQLN 4023
            + K++WI +G ALLCQL+
Sbjct: 4140 RSKDYWIAKGSALLCQLS 4157


>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
          Length = 4427

 Score = 2454 bits (6360), Expect = 0.0
 Identities = 1401/3693 (37%), Positives = 2107/3693 (57%), Gaps = 192/3693 (5%)

Query: 399  HPGFIMRLILDNDT------IKFEPELSDYIDIFLNVYDVMIKAVSF---VPRVETKLYS 449
            +P F + +IL ND       ++F P L     +  ++ + +   +S    +P + TK   
Sbjct: 860  NPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK--- 916

Query: 450  KWESKSKPTTLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDV 509
                  +    +PI   + V    E IK++  + S   T +  L   Y  L T    R++
Sbjct: 917  ------RKLHREPI---QTVVEQDEDIKKIQTQISSGMTNNASLLQNY--LKTWDMYREI 965

Query: 510  -----DNFLAENHSYEKI-------IDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELI 557
                 D+F+   H Y+++       + +I +Y ++   +Q     T  +    + C  L 
Sbjct: 966  WEINKDSFI---HRYQRLNPPVSSFVADIARYTEVANNVQKEETVT-NIQFVLLDCSHLK 1021

Query: 558  RALVKRADIICGKLLAKMFRDHQ-----EVNTRLCDEFERIAEKALSTPPNTAELMEMKA 612
             +LV+  +    K  A + R+       E++T L +  E+I     S PP T E + +  
Sbjct: 1022 FSLVQHCNEWQNKF-ATLLREMAAGRLLELHTYLKENAEKI-----SRPPQTLEELGVSL 1075

Query: 613  YIQKVEVTDMIELEQRLVDSKNCLAFLIEY-VNFSPADMRLNNSVFQWYGRMGEIFEEHR 671
             +      D+  +E ++       A L +Y V    + + + +S+   +    +   + +
Sbjct: 1076 QLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSK 1135

Query: 672  KIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDL 731
            +++K+  E+++ GL    + F ++  +     E+F   G       Y+     +     +
Sbjct: 1136 QMLKKHKEKFKTGLIHSADDFKKKAHTLL---EDFEFKGHFTSNVGYMSALDQITQVRAM 1192

Query: 732  AADKIEQFNAEEEAFGWLPSVYPQRKKIQD---GLNPYLRLYETAVEFSSNYRAWTEGPY 788
                 E+ N+     G      P  K +Q+    L+   +++E A ++  N+  W  G +
Sbjct: 1193 LMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRF 1252

Query: 789  HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848
              +  + +E      +R L KL K + D  + +  T   RSK+E FK+ +PLI  + NP 
Sbjct: 1253 LILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIET--TRSKIEQFKRTMPLISDLRNPA 1310

Query: 849  LRPRHWEAMSAIVGYPL-QPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEK 907
            LR RHW+ +   +     Q S+  T+   +++ ++ ++++   IS +A+KE ++E A++ 
Sbjct: 1311 LRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQN 1370

Query: 908  MITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWE 967
            +   WD  +  I  Y++ G   L   +E+   L+D+ +   TM+ S F+K +EK +  WE
Sbjct: 1371 IAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWE 1430

Query: 968  GKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027
              L L+ E+++  L VQ  W+YLE IF   DI  Q+P E   F  V+  W+ IM  + +D
Sbjct: 1431 RCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKD 1490

Query: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087
             + L       +L+ L + N +LE I K L+ YLE KR  FPRF+FLSND+LLEIL +++
Sbjct: 1491 NNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSR 1550

Query: 1088 DPTRVQPHLKKCFEGIAKVEFTET------LDITHMKSSEGEVVELIEIISTAKARGQVE 1141
            +P  VQPHLKKCF+ I  +   +        +   M S +GE ++ +  +      G VE
Sbjct: 1551 NPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFL---EGPVE 1607

Query: 1142 KWLVELERVMINSIHKVTGDATFAYTKY--ERINWVRDWPGQTVLCVSQIFWTKEV-QTA 1198
             WL ++E+ M  ++  +  +   A  K+  +R  WV++W GQ V+  SQI WT +V +  
Sbjct: 1608 SWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCL 1667

Query: 1199 IPMGIKALEQYLKTCNRQIDDIVT----LVRGKLSMQNRVTLGALVVLDVHARDVLSSLV 1254
            +    +A ++ LK   +    I+      +RG L+   R+ + ALV +++HARDVL  L 
Sbjct: 1668 LTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLY 1727

Query: 1255 KKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYR 1312
            K  + D + F+WLSQLR+YW+++      +  N   +Y YEYLGNS RLVITPLTDRCY 
Sbjct: 1728 KSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYM 1787

Query: 1313 TLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLS 1372
            TL  ALHLH GG+P+GPAGTGKTET KDL KA+    +V NCS+GLDY ++G+ + GL  
Sbjct: 1788 TLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQ 1847

Query: 1373 CGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNP 1432
             GAW CFDEFNRI++EVLSVVA QIL I   + AG     F+G E+ L  +C +FITMNP
Sbjct: 1848 TGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNP 1907

Query: 1433 GYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQL 1492
            GYAGR+ELP+NLK++FR +AM+VPD  +IAEI+L+  GF   + L+ K+   Y L  +QL
Sbjct: 1908 GYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQL 1967

Query: 1493 SSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGIT 1552
            S Q HYD+G+RA+ S+L  AG  +   P+  +E +LL S+ D+N+ K  S D PLF  I 
Sbjct: 1968 SRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIV 2027

Query: 1553 SDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPF 1612
             DLFP ++LP  DY  L   ++     M LQ T F   K+ Q+YE    RH  MIVG   
Sbjct: 2028 QDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTG 2087

Query: 1613 GGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLA 1672
             GKT+++R+L  +L+ +C  G    N V+   LNPK++++G+LYG++D  ++EW+DG+L+
Sbjct: 2088 SGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILS 2147

Query: 1673 VSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFE 1732
               R   +   PD KW++FDGPVD +WIENMN+V+DDNK L L++GE I M  Q++L+FE
Sbjct: 2148 SVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFE 2207

Query: 1733 PMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLP-ASVSVIQKEFIMGLFDRMVP 1791
              DL +ASPATVSRCGM+Y +   LGW+P + SW+   P A V  +Q+     +F++++ 
Sbjct: 2208 VEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQR-----MFEKLIN 2262

Query: 1792 VSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLF 1851
              + F + + KEL P  + + + SL  L          E  +   +     +++E  F+F
Sbjct: 2263 KMLAFKKDNCKELVPLPEYSGITSLCKLYSALA---TPENGVNPADGENYVTMVEMTFVF 2319

Query: 1852 SLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKG 1911
            S+IWSV AS  ++ R + +  LRE+  S                           FP K 
Sbjct: 2320 SMIWSVCASVDEEGRKRIDSYLREIEGS---------------------------FPNKD 2352

Query: 1912 TIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKP 1971
            T+Y+Y FV   I  W  +  KL ++   P +  F +I+VPT+DT+RY+ L+  L  +Q P
Sbjct: 2353 TVYEY-FVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNP 2411

Query: 1972 SIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVF 2031
             + VGP GTGK+  I   +L  L    +  L++N SAQTT+   Q+I+ S+++KR KGV+
Sbjct: 2412 ILLVGPVGTGKT-SIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVY 2470

Query: 2032 GPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCA 2091
             P  GK M+ F+DD+NMPA++++G+QPP+EL+R W+D+  WYD    ++  + ++ +M A
Sbjct: 2471 VPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAA 2530

Query: 2092 MGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQ 2151
            MGPPGGGR  ++PR    FNII +   +   +  IF  ++   L+    F +E   +   
Sbjct: 2531 MGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQ---DFEEEVKPIGNV 2587

Query: 2152 IVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHE 2211
            +   T+ +Y   ++  LPTP K HYLFNLRD S+V QG+  +  +  +T   I RLW+HE
Sbjct: 2588 VTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHE 2647

Query: 2212 VLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFC 2271
              RV+ DRL+D  D    +  I + L ++    FH L                 R  +F 
Sbjct: 2648 CFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHL-------------CPSKRPPIFG 2694

Query: 2272 DFHDPKREDTNYREIADVDNLRMIVEIHLEEYN-NISKKPMNLVLFRFAIEHISRISRIL 2330
            DF    +E   Y ++ D+  L+ ++E  L EYN + S  PM LVLFR AIEHI+RI R++
Sbjct: 2695 DF---LKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVI 2751

Query: 2331 KQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEG 2390
             QPR + LLVG+GGSGRQS+ RLA+ + DY+ FQ+E++K Y   E+ +D+K + R+    
Sbjct: 2752 GQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVE 2811

Query: 2391 EMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQT 2450
                 F+F DTQI +ESFLED++N+L++GE+PNL+  DE +EI  +   +D+ R   +Q 
Sbjct: 2812 LKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEI--QSHIIDQAR--VEQV 2867

Query: 2451 DGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQ 2510
              S  +LF   I+  ++ LH+VL +SP+GD FRN +R++PALVNC TI+WF  WP++AL 
Sbjct: 2868 PESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALL 2927

Query: 2511 AVASRFLEEIEM--SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELIS 2568
             VA + L  +++   E I      +  + H S    S+   +EL+R+NYVTPT YLEL+S
Sbjct: 2928 EVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLS 2987

Query: 2569 TFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMI 2628
             +K LL +KR E++    +   GL K+D    +V  M +ELE    ++    K+ +E ++
Sbjct: 2988 GYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLV 3047

Query: 2629 MIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTA 2688
            +I ++  E  + +K V A+      + +  +A+ D    DL  ALP LE A+ AL++L  
Sbjct: 3048 IIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNK 3107

Query: 2689 QDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRF 2748
            +DI  +KS   PPA V++VM+A+ IL+G       +PT         W  AKR LG+  F
Sbjct: 3108 KDIGEIKSYGRPPAQVEIVMQAVMILRG------NEPT---------WAEAKRQLGEQNF 3152

Query: 2749 LQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAK 2808
            ++SL  +DKDNI    +  I   Y   PDF P+ I   S AA+ LC WV AM+ Y ++ +
Sbjct: 3153 IKSLINFDKDNISDKVLKKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYR 3211

Query: 2809 IVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ-------KKAD 2861
            +V PK+I++ AA  +       LR+KQAAL E Q+KL  + + LE+ K+       +K +
Sbjct: 3212 VVEPKRIRMNAALAQ-------LREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEE 3264

Query: 2862 LENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAF 2921
            L  + +    KLERA  L+ GL GEK RW  T   L +    L GD L+++  ++Y+G F
Sbjct: 3265 LRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPF 3324

Query: 2922 TSTYRQNQTKE-WTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGII 2980
             + YR     + W        +PCS   ++   L     +R WNI GLPSD+FS +NGII
Sbjct: 3325 LTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGII 3384

Query: 2981 IMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVG 3040
            +    RW LMIDPQ+QA KWIKNME    L +I L   DY+R LE+ I FG PVLL+NV 
Sbjct: 3385 VTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQ 3444

Query: 3041 EELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTL 3100
            E LDP L P+L K   + GG   +R+GD  +EY  +FRFYITTKL NPHY PETS K T+
Sbjct: 3445 EYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTI 3504

Query: 3101 LNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEG 3160
            +NF +  +G++ QLLGIVV +ERP+LEE+K +L++  A  KR+LKE+ED+IL +L+ + G
Sbjct: 3505 VNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATG 3564

Query: 3161 NILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADL 3220
            ++L+D   +  L +SK  A E++++ E +E TE   D  R  YRP A  +SILFF L D+
Sbjct: 3565 SLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDM 3624

Query: 3221 ANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKL 3280
              I+PMYQ+SL  +I+LFILSI+ S +S  L  R+  L D+ TY++Y   CR+LFE+ KL
Sbjct: 3625 GCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKL 3684

Query: 3281 LFSFCLTINLLLHERAINKAEWRFLLTGGIGLD--NPYANLC-TWLPQKSWDEICRLDDL 3337
            LFSF +   +L     +N  E+ F L GG+ LD      N C +WL    WD I  LD L
Sbjct: 3685 LFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKL 3744

Query: 3338 PAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPML 3397
              F  +   F +    W   Y +  P   + P EWE+  NE QRMLI+R LR D+V   +
Sbjct: 3745 TNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCV 3804

Query: 3398 QEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSK 3457
              FII  LG  FIEPP  ++     DS   +PL+F+LSPG DP +ALL+ A+  G    +
Sbjct: 3805 TSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM-AQR 3863

Query: 3458 LSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFR 3517
              +LSLGQGQ PIA ++L + V +G WV L NCHL+ SWMP L+K+ E+L  E  HP FR
Sbjct: 3864 FHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFR 3923

Query: 3518 MWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKK 3577
            +WL+S P P+FP+S+LQ  +KMT E PKGL+AN+ R Y +  +S+P+ F  C KP ++KK
Sbjct: 3924 LWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQL--MSEPQ-FSRCSKPAKYKK 3980

Query: 3578 LLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMT 3637
            LL+ LCFFH+++ ER+KF  LGWNI Y FN++D  +S   L ++L++YEE P++AL+Y+ 
Sbjct: 3981 LLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLI 4040

Query: 3638 GECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTK 3697
               NYGG VTDDWDRR L + +N +F  + +    ++  +   YF+P  G   SY EY  
Sbjct: 4041 AGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYIS 4100

Query: 3698 TLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDEVVNEVASD 3755
             LP    PE FG + NAD+    +E Q LFD +L  Q +     AG ++ +E V E+A+D
Sbjct: 4101 LLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAAD 4160

Query: 3756 ILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAV 3815
            +  K+P   D E   +         +N VL+QE+ R+N L++TI  S  +++K I+GL V
Sbjct: 4161 VKQKIPEMIDYEGTQKLLALD-PSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIV 4219

Query: 3816 MSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFW 3874
            MST LEE+ + I +  +P +W GK+YPS KPL ++  D   R++  + W     PP +FW
Sbjct: 4220 MSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFW 4278

Query: 3875 LSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEV--MEDKEYKHPPEDGVFIHGLFLDG 3932
            LSGF F   FLT   Q+ AR+  + +D L +++ V  ++D    +PP+DGV++ GL+L+G
Sbjct: 4279 LSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEG 4338

Query: 3933 ASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGH 3992
            A W+RK   L E+ P  L   +P +  +P +      +  Y  P Y    R G    +  
Sbjct: 4339 AGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSD 4394

Query: 3993 STNFVIAMTLPSD-QPKEHWIGRGVALLCQLNS 4024
              +FVI + L S     +HWI RG ALL  L+S
Sbjct: 4395 RASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS 4427


>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
          Length = 3092

 Score = 2092 bits (5421), Expect = 0.0
 Identities = 1096/2238 (48%), Positives = 1484/2238 (66%), Gaps = 57/2238 (2%)

Query: 165  YYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDS---IVTLSDEMREDYLLSVRKS 221
            Y Y+   +++  + P++  WL+H+L L+P+ LK   +    + +L +E+  D+  S+++ 
Sbjct: 96   YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155

Query: 222  IVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAV 281
            +V  VL  P  K  + +   LP     ++    PW  S++ A + I  +L+ ++PTM  +
Sbjct: 156  LVQSVLVKPPVKSLEDEGGPLPESPVGLDY-SNPWHSSYVQARNQIFSNLHIIHPTMKML 214

Query: 282  LDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQ 341
            LDL +T F    L+D       +  ++  S +  +     +A+E ++  W+P+V N++  
Sbjct: 215  LDLGYTTFADTVLLDFTGIR-AKGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF-- 271

Query: 342  GNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPG 401
               KK+   G    KL++F++C + LM+ QL+DL   +++ F  L   P D  R    P 
Sbjct: 272  --TKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-DPKDQQRL---PI 325

Query: 402  FIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLK 461
            F + L  D+D ++F P   D  D  L++ + + +A+  V  + + L       +  T L 
Sbjct: 326  FKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELP 385

Query: 462  PIILNEIVDAHKEKIKEVIMKESVAPTEHLRLY-DKYDFLITRKAERDVDNFLAENHSYE 520
              +L+  VD     +K  + +      +H   Y +KY++L+   A  +++ F  E+H+++
Sbjct: 386  EHVLHWAVDT----LKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFD 441

Query: 521  KIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQ 580
            +  + I K+  L  EI     + I   M  + CE+L   L  +A      LL  +   ++
Sbjct: 442  EYTEFIEKFLSLASEIMLLP-QWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYR 500

Query: 581  EVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLI 640
            + N  +C EFE I E AL  P  T E+M++ +Y++K     + EL  R+ +SK  +++ +
Sbjct: 501  KENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFL 560

Query: 641  EYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYA 700
            +   F   D+ LN +V  W  ++  IF+E+ ++I+    + +  L  + E+ + E+E  +
Sbjct: 561  DVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKES 620

Query: 701  KQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQ 760
            ++ EEF  F +L+ +Q+Y+   + L  ++  + + ++  N EEE F W  + YP+  K++
Sbjct: 621  RRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLK 680

Query: 761  DGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYK--------LEK 812
              + PY + +   +++  + + W +G +  +N + +EAD+  + R ++K        L+K
Sbjct: 681  VNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKK 740

Query: 813  TFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDST 872
               +   A         K+E+  +    I  +C   +R RHW+ +S IVGY L P   +T
Sbjct: 741  ELQEKRKAARKRSLEEEKIEEEPKDNATI-TMCR--MRARHWKQISEIVGYDLTPDSGTT 797

Query: 873  VSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILAS 932
            +   L +NL PY+++FE IS  ASKE+SLEKAM  MI  W+ + F I  YR+TG  IL+S
Sbjct: 798  LRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSS 857

Query: 933  VDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEP 992
            VDEIQ +LDD IIKTQTMRGSPFIKP+E +++ WE +L+ +QE +DEWLKVQA WLYLEP
Sbjct: 858  VDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEP 917

Query: 993  IFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLEL 1052
            IF S DIM QMPEEGR+F  VD+ WRDIM+   +D  VL   ++  +LE+L+  NELLE 
Sbjct: 918  IFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEK 977

Query: 1053 ILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETL 1112
            I+KGLN YLEKKRLFFPRFFFLSNDE+LEILSETKDP RVQPHLKKCFEGIAK+EF   L
Sbjct: 978  IMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNL 1037

Query: 1113 DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERI 1172
            DI  M SSEGE VELI +IST+ ARG VEKWL+++E +M+ S+H V   A  AY +  R 
Sbjct: 1038 DIKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARR 1097

Query: 1173 NWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQN 1232
            +WVR+WPGQ VLC+SQ+FWT E Q  I  G + L++Y K    Q+++IV LVRGKLS Q 
Sbjct: 1098 DWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQT 1157

Query: 1233 RVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETKMINAGLRYGY 1292
            R TLGALV +DVHARDV+  ++K  +S D+DF WL+QLRYYW+  +   ++IN  ++Y Y
Sbjct: 1158 RTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIINCNVKYAY 1217

Query: 1293 EYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVF 1352
            EYLGNSPRLVITPLTDRCYRTL GA +L+LGGAPEGPAGTGKTETTKDLAKA+A QCVVF
Sbjct: 1218 EYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVF 1277

Query: 1353 NCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILM 1412
            NCSDGLDYLA+GKFFKGL S GAWACFDEFNRI+LEVLSVVAQQIL IQR I     + +
Sbjct: 1278 NCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFV 1337

Query: 1413 FEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFV 1472
            FEGTELKL+P C V ITMNPGYAGRSELPDNLK LFRTVAMMVP+YA+IAEI LYS GF+
Sbjct: 1338 FEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFL 1397

Query: 1473 TARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSI 1532
             ARPLSVKIV TYRLCSEQLSSQ HYDYGMRAVK+VL AAGNLKLKYPNENE+ILLLRSI
Sbjct: 1398 NARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSI 1457

Query: 1533 IDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKI 1592
             DVN PKFLSHD+PLF GITSDLFPG+KLP+ DY++ L    + C   NLQ   FF EKI
Sbjct: 1458 KDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKI 1517

Query: 1593 LQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTM 1652
            +Q YEMMIVRHGFM+VGEPF  KT    VLA  L  + E G  EE KV    +NPKS+TM
Sbjct: 1518 IQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITM 1577

Query: 1653 GQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKK 1712
            GQL+GQFD VSHEW+DG++A +FR FA S TPDRKW++FDGP+D +WIE+MNTVLDDNKK
Sbjct: 1578 GQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKK 1637

Query: 1713 LCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPA 1772
            LCLMSGEIIQMSPQM+LIFE MDL  ASPATVSRCGMIY+EP  LGW PL+ SW+N L  
Sbjct: 1638 LCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKG 1697

Query: 1773 SVSVIQKEFIM-GLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEV 1831
             +   + + ++ GLF  ++P S+   R    +L+    T + + L  LI   + ++   V
Sbjct: 1698 PLCEPEYQALLRGLFAWLIPPSLN-QRVELFQLNYLYTTIVSKILKILITFRISNYFKYV 1756

Query: 1832 KLKERNDRETYSL-LEGIFLFSLIWSVGASCTDDDRLKFNKILRELM-----ESPISDRT 1885
             LK +     + L  +  F+FSLIWS+G SC  D R  F+  +R ++     E+P+ D  
Sbjct: 1757 PLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPD-- 1814

Query: 1886 RNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMF 1945
                         S      PF EKG +YDY +  +  G+W  W + +K      K +  
Sbjct: 1815 -------------SVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKI 1861

Query: 1946 NEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLIN 2005
             +IIVPT+DTIRY+ LM+L  T+ KP +FVGPTGTGKSVY+ + L+N L K+ Y P  IN
Sbjct: 1862 QDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYIN 1921

Query: 2006 FSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQ 2065
             SA+T+A Q QNI+M++LDKRRKGVFGPP+GK+ ++F+DD+NMPA E YGAQPPIELLRQ
Sbjct: 1922 LSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQ 1981

Query: 2066 WLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYT 2125
            + D  +WYDLKD S I LVDI+++ AMGPPGGGRNPVTPR +RHFNI +IN FSD++M  
Sbjct: 1982 FFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVR 2041

Query: 2126 IFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSR 2185
            IFS I+ ++L   ++FP E+  +  QIVNGTM +YK++++NLLPTP KSHY FNLRDFSR
Sbjct: 2042 IFSSIVAFYLR-THEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2100

Query: 2186 VIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDF 2245
            VI+G  L   +       + RL+VHEVLRV+YDRL+++ DR WL    + +++++  E F
Sbjct: 2101 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESF 2160

Query: 2246 HELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRE--DTNYREIADVDNLRMIVEIHLEEY 2303
            H +F  L   N  + E +DLR+LMF D+ +P  E  D  Y EI ++ +   +V+  L+EY
Sbjct: 2161 HSIFSHLRKQNAPVTE-EDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEY 2219

Query: 2304 NNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVF 2363
            N   K  MNLV+FR+ +EH+SRI R+LKQ   +ALLVG+GGSGRQS+TRLA  MA   +F
Sbjct: 2220 NQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIF 2279

Query: 2364 QVEISKGYDTTEWHEDLK 2381
            Q EISK Y   EW ED+K
Sbjct: 2280 QPEISKSYGMNEWREDMK 2297



 Score = 1006 bits (2602), Expect = 0.0
 Identities = 472/780 (60%), Positives = 603/780 (77%), Gaps = 3/780 (0%)

Query: 3247 KSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLL 3306
            KS+IL KRL+ L DHFTY+LY N+CRSLFEKDKLLFSF L  NLLL  + I   E  FLL
Sbjct: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371

Query: 3307 TGGIGLDNPYANLC-TWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHH 3365
            TGG+ L +   N   TWL  KSW+EICR  + PAF+ +R+ F      W+++YDS EPH+
Sbjct: 2372 TGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHN 2431

Query: 3366 EVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSN 3425
              FP   +   NE Q+++I+RCLRPDK+ P +  ++ ++LG+ F+EPPPFDL K++ DSN
Sbjct: 2432 AKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSN 2491

Query: 3426 CCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWV 3485
            C  PLIFVLSPGADPMA+LLKFA+D+   G+K  ++SLGQGQGPIA KM++ A++EGTWV
Sbjct: 2492 CTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWV 2551

Query: 3486 VLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPK 3545
             LQNCHLA SWMP LEK+CE+ + E+ +  FR+WLTSYPS  FPV++LQNGVKMTNE P 
Sbjct: 2552 CLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPT 2611

Query: 3546 GLRANIIRSYLMDPISDPEFFGSCKKPE-EFKKLLYGLCFFHALVQERRKFGPLGWNIPY 3604
            GLR N+++SYL DP+SDPEFF  C+  E  ++KLL+G+CFFHALVQER+KFGPLGWNIPY
Sbjct: 2612 GLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPY 2671

Query: 3605 EFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFN 3664
             FNE+DLRIS++QL +F+N+Y+ +P+EA+ Y+TGECNYGGRVTDDWDRR L ++L  F+N
Sbjct: 2672 GFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYN 2731

Query: 3665 PELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQ 3724
              +VEN  YKF  SG YF PP G ++ YIE+ K LP T  PEIFG++ N DI+KD  +T+
Sbjct: 2732 LYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTK 2791

Query: 3725 LLFDNILLTQSRSAGAGAK-SSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNT 3783
             LF+++LLTQ  S   GA  S+D+++ E+  DIL KLP++FDIE A+R+YP  Y +SMNT
Sbjct: 2792 TLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMNT 2851

Query: 3784 VLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPS 3843
            VLVQEM RFN L+ TIR++  +++KAIKG+ VM + LE +  S+L  K+PE+W  +SYPS
Sbjct: 2852 VLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPS 2911

Query: 3844 LKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLL 3903
            LKPLGSY+ DFLARL FLQ WY  G P VFWLSGFFFTQAFLTGA QNYARKYT PIDLL
Sbjct: 2912 LKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLL 2971

Query: 3904 GFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCK 3963
            G+++EV+        PEDGV+IHGL+LDGA W+R+   LAE +PK+L+D +P++W+KP +
Sbjct: 2972 GYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQ 3031

Query: 3964 RADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLN 4023
            ++ I K  +YV PLYKTSER+G LSTTGHSTNFVIAM L +DQP  HWI RGVALLCQL+
Sbjct: 3032 KSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLD 3091


>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
          Length = 4471

 Score = 2056 bits (5328), Expect = 0.0
 Identities = 1239/3557 (34%), Positives = 1961/3557 (55%), Gaps = 175/3557 (4%)

Query: 519  YEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRD 578
            Y KI  E+ ++  + +E        IRL +   H    ++   K   I  GKLL +  ++
Sbjct: 1028 YSKIAYEVMRHPLIKDE------HCIRLQL--RHLANTVQENAKSWVISLGKLLNESAKE 1079

Query: 579  HQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAF 638
                   L +E E +A+     P    +L  + A I ++    ++ +E R  D +     
Sbjct: 1080 ELY---NLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLV-MELRYRDVQERYRT 1135

Query: 639  LIEYVNFSP-ADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELE 697
            +  Y  F P A+  L + +   +  +          + +    + E  +     +  ++E
Sbjct: 1136 MAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIE 1195

Query: 698  SYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQ 755
             +AK+  SE   S GD  D+ + ++   +   +L       ++    E+ F    ++YP+
Sbjct: 1196 EFAKRFYSEGPGSVGD--DLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPE 1253

Query: 756  RKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFH 815
              K+Q  ++    +YE           W++  +  +N   ++  I  + R L KL +   
Sbjct: 1254 LLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVR 1313

Query: 816  DSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSS 875
                 L++T  + +K++ FK  IPL+  + N  LR RHW+ +        + ++  T+ +
Sbjct: 1314 ----GLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLEN 1369

Query: 876  FLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSY----RETGTFILA 931
               M L  + D    I  AA KE ++EKA+++++  W+ ++F +  Y    +E G +IL 
Sbjct: 1370 MFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERG-YILG 1428

Query: 932  SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLE 991
            SVDEI   LDD+    Q++ GS F+ P+ + + +WE  L L+ E+++ W+ VQ  W+YLE
Sbjct: 1429 SVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLE 1488

Query: 992  PIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLE 1051
             IF   DI SQ+PEE ++F  +DK ++ IM   ++D  +         L  L+  +E LE
Sbjct: 1489 SIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLE 1548

Query: 1052 LILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET 1111
               K LN+YL+ KR  FPRFFF+S+DELL IL  + DP  VQ H+ K ++ IA + F + 
Sbjct: 1549 KCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMYDNIASLRFNDG 1607

Query: 1112 LD----ITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYT 1167
                  ++ M S+EGEV+E  +I+   +A G+VE W+  +   M  +   +T +A F Y 
Sbjct: 1608 DSGEKLVSAMISAEGEVMEFRKIL---RAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYC 1664

Query: 1168 K-YERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK----ALEQYLKTCNRQIDDIVT 1222
            +   R++W+  + G  VL  SQ++WT EV+       K    A++ Y +  +RQID++VT
Sbjct: 1665 EDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVT 1724

Query: 1223 LVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW--QENHLE 1280
             +   LS  +R     ++++DVHARD++ S ++ +I +  +F+W SQLR+YW  + + L 
Sbjct: 1725 RITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELN 1784

Query: 1281 TKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKD 1340
             +       YGYEY+G + RLVITPLTDR Y TL  AL ++LGGAP GPAGTGKTETTKD
Sbjct: 1785 IRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKD 1844

Query: 1341 LAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTI 1400
            LAKA+   CVV NC +G+DY A+GK F GL  CGAW CFDEFNRID  VLSV++ QI TI
Sbjct: 1845 LAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTI 1904

Query: 1401 QRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAM 1460
            +  +        FEG E+ LD    +FITMNPGYAGR+ELP+++KALFR V ++VPD   
Sbjct: 1905 RNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQ 1964

Query: 1461 IAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYP 1520
            I EI+L+S GF+ A+ L+ K+   Y+L  EQLS Q+HYD+G+RA+KSVL  AG LK    
Sbjct: 1965 ICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSS 2024

Query: 1521 NENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPK---PDYNDLLAAI--KD 1575
            +  E+++L+R++ D+NLPKF+  D+PLF G+ SDLFPG+  P+   PD+ND +  +  ++
Sbjct: 2025 DLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEEN 2084

Query: 1576 NCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLM 1635
              A + +Q+     +K++Q++E M+ RH  M+VG   GGK+         +N +C+    
Sbjct: 2085 GYAVLPIQV-----DKVVQMFETMLTRHTTMVVGPTRGGKSV-------VINTLCQAQTK 2132

Query: 1636 EENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSV-TPDRKWLIFDGP 1694
                 ++ +LNPK+V++ +LYG  D  + +W+DGVL+  FR         +RK+++FDG 
Sbjct: 2133 LGLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGD 2192

Query: 1695 VDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEP 1754
            VDA+W+ENMN+V+DDN+ L L +GE I++     L+FE  DL+ ASPATVSRCGM+Y++P
Sbjct: 2193 VDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDP 2252

Query: 1755 HMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFI---------RKHTKELS 1805
              L +RP    WVN +P   + +++  +  LF++ VP  ++ I          +  K + 
Sbjct: 2253 KNLKYRPYWKKWVNQIP---NKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIV 2309

Query: 1806 PTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDD 1865
            P +D N+V  L  ++D  ++            + E   LLE  FL +L  S+GAS  +D 
Sbjct: 2310 PQTDLNMVTQLAKMLDALLE-----------GEIEDLDLLECYFLEALYCSLGASLLEDG 2358

Query: 1866 RLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGK 1925
            R+KF++ ++ L      D           TE   +    +P  +  T+YD+ F  +   +
Sbjct: 2359 RMKFDEYIKRLASLSTVD-----------TEGVWANPGELP-GQLPTLYDFHFDNKR-NQ 2405

Query: 1926 WEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVY 1985
            W PW K + E    P+    N I+V T+DT R + ++E +   ++P IFVG +GT K+  
Sbjct: 2406 WVPWSKLVPEYIHAPERKFIN-ILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTAT 2464

Query: 1986 ITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDD 2045
              NFL N L++E    L++NFS++TT+   Q  + + ++KR K  +GPP+GKR++VF+DD
Sbjct: 2465 TQNFLKN-LSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDD 2523

Query: 2046 VNMPAREVYGAQPPIELLRQWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTP 2104
            +NMP  + YG Q PI LL+  L+    YD  K+ +   + D+  + AMG  GGGRN V P
Sbjct: 2524 MNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDP 2583

Query: 2105 RYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAM 2164
            R++  F++  +   S++S++ I+S IL  H      F +  + ++ ++   T+ LYK  +
Sbjct: 2584 RFISLFSVFNVPFPSEESLHLIYSSILKGHTS---TFHESIVAVSGKLTFCTLALYKNIV 2640

Query: 2165 KNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNT 2224
            ++L PTP+K HY+FNLRD SRV  G+ L+ PE  +T   + R+W +E LRV++DRL+  T
Sbjct: 2641 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 2700

Query: 2225 DRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDP--KREDTN 2282
            D+  +  +I  ++  +  +D               VE      ++F DF     + E   
Sbjct: 2701 DKQLVQQHIGSLVVEHFKDD---------------VEVVMRDPILFGDFQMALHEGEPRI 2745

Query: 2283 YREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGV 2342
            Y +I D +  + + +  LEEYN  + K MNLVLF  A+EH++R+ RI++  R HALLVGV
Sbjct: 2746 YEDIQDYEAAKALFQEILEEYNESNTK-MNLVLFDDALEHLTRVHRIIRMDRGHALLVGV 2804

Query: 2343 GGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQ 2402
            GGSG+QS++RLAA  A   VF++ +S+GY    + EDLK +  K        +FLFTD  
Sbjct: 2805 GGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAH 2864

Query: 2403 IKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDG-SPIALFNMF 2461
            + EE FLE ++N+L +G +P LF+ +EK+ I  ++ Q     +  KQ  G +  +++  F
Sbjct: 2865 VAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQ-----EALKQGMGPAKESVWQYF 2919

Query: 2462 IDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIE 2521
            ++   + LH+VL MSP+GD  R   R FP +VN   IDWF  WP  AL AVA  FL    
Sbjct: 2920 VNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNP 2979

Query: 2522 M-SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE 2580
            M   E  +  +      H S    S+ F  +L+R NYVTP +YL+ I+T+  LL++K   
Sbjct: 2980 MIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQC 3039

Query: 2581 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT 2640
             +   KR + GL+KL  A+ Q+  +  +L     Q  V +++      ++E+ +V  A  
Sbjct: 3040 NIAQCKRLDGGLDKLKEATIQLDELNQKLA---EQKIVLAEKSAACEALLEEIAVNTAVA 3096

Query: 2641 EKIVKADETIANEQAMASKAI---KDECDADLAGALPILESALAALDTLTAQDITVVKSM 2697
            E+  K  E  A E    +K I   K E +  LA  +PILE+A   L  L   D+T ++S 
Sbjct: 3097 EEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSF 3156

Query: 2698 KSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDK 2757
              PP  V+ V E I I+KG K              E  W  AK ++ D  FL+SL E D 
Sbjct: 3157 AKPPKQVQTVCECILIMKGYK--------------ELNWKTAKGVMSDPNFLRSLMEIDF 3202

Query: 2758 DNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKL 2817
            D+I  + +  I K  +   +   E++   S A  G+ K+V A+  Y  V + + PK+ K+
Sbjct: 3203 DSITQSQVKNI-KGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKV 3261

Query: 2818 AAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAE 2877
            A  E    +    L + Q  L  +Q +L  L    E    +K  L+ + ++  ++L  A+
Sbjct: 3262 ARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAAD 3321

Query: 2878 QLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKE-WTTL 2936
            +LI GLG E  RW +   EL    + L GD L+ +  ++Y GAFT  +R       W   
Sbjct: 3322 KLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQND 3381

Query: 2937 CKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQ 2996
               R+IP S    L   L + V I  W   GLP D  S+ NGI+   A R+PL IDPQ Q
Sbjct: 3382 ILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQ 3441

Query: 2997 ANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTF 3056
            A  WIK  E+ N+L V   ++PD+++ LE  I++GTP L  +V E +DP+++ +L K   
Sbjct: 3442 ALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIK 3501

Query: 3057 KQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLG 3116
               G   I LGD  ++Y  +FR Y+ TKL NP Y P    K  ++N+ +T +G++DQLL 
Sbjct: 3502 VSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLS 3561

Query: 3117 IVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSK 3176
            ++VA ER +LEE+++ LI + +ENK  LK++ED +L  L++S GN+L++   +  L  +K
Sbjct: 3562 VLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETK 3621

Query: 3177 ALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFIN 3236
            + A E+S+K ++AE+T   ID  R GYRP A   +ILFF L+++A +  MYQYSL  F+ 
Sbjct: 3622 SKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLE 3681

Query: 3237 LFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERA 3296
            +F LS++ S    IL KRL+ + D  T+S+Y + C  LFE+ KLLFSF +TI +   E  
Sbjct: 3682 VFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGR 3741

Query: 3297 INKAEWRFLLTGGIGLD-NPYANLCTWLPQKSWDEICRLDDL--PAFKTIRREFMRLKDG 3353
            + + E  F L G I L+ +     C WL  + W++I  L ++    F  +  +    +  
Sbjct: 3742 VPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTV 3801

Query: 3354 WKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPP 3413
            W++ YD         P  +++    FQ++LI+RC R D+V   + +++   +G  +++PP
Sbjct: 3802 WQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPP 3861

Query: 3414 PFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMK 3473
                   F  S   +P++F+LSPG+DP   L+K A+  G+GG++L  L++GQGQ  +A++
Sbjct: 3862 MISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQ 3921

Query: 3474 MLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVL 3533
            +LE AV  G W++LQNCHL   W+  LEK  E ++    HPDFR+WLT+ P+  FP+ +L
Sbjct: 3922 LLETAVARGQWLMLQNCHLLVKWLKDLEKSLERIT--KPHPDFRLWLTTDPTKGFPIGIL 3979

Query: 3534 QNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERR 3593
            Q  +K+  E P GL+ N+  +Y        E    C  P  FK L+Y L FFHA+VQERR
Sbjct: 3980 QKSLKVVTEPPNGLKLNMRATYFK---ISHEMLDQCPHP-AFKPLVYVLAFFHAVVQERR 4035

Query: 3594 KFGPLGWNIPYEFNETDLRISVQQLHMFLNQY-----EELPYEALRYMTGECNYGGRVTD 3648
            KFG +GWN+ Y+FNE+D ++ ++ L+ +L +        +P+ +L+Y+ GE  YGGR  D
Sbjct: 4036 KFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAID 4095

Query: 3649 DWDRRTLRSILNKFFNPELVENSD--YKFDSSGIYFVPPSGDHK-SYIEYTKTLPLTPAP 3705
             +DRR L   ++++    + +     + F +  + +  P GD K  ++E  + LPL   P
Sbjct: 4096 SFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTP 4155

Query: 3706 EIFGMNANADITKDQSETQLLFDNILLTQSRSA-GAGAKSSDEVVNEVASDILGKLPNNF 3764
            E+FG++ NA+I       + ++ ++L  Q ++   +   S D+ + +VA +I  K+P  F
Sbjct: 4156 EVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVF 4215

Query: 3765 DIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVV 3824
            D++   +R  T  + + + VL+QE+ RFNKL+  +  S   +Q+A+ G   MS +L++V 
Sbjct: 4216 DLDQVRKRLGTGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVA 4274

Query: 3825 SSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAF 3884
             S+    IP +W   +  +LK LG+++  FL R      W     P V WLSG    +++
Sbjct: 4275 RSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESY 4334

Query: 3885 LTGAQQNYARKYTIPIDLLGFDYEV---MEDKEYKHPPEDGVFIHGLFLDGASWNRKIKK 3941
            LT   Q   RK   P+D      +V    +  E       G F+ GL+L+GA W+ +   
Sbjct: 4335 LTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGC 4394

Query: 3942 LAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMT 4001
            L +S PK+L   +P++ + P +   +  + ++  P+Y TS RR  +         V    
Sbjct: 4395 LIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEAD 4449

Query: 4002 LPSDQPKEHWIGRGVAL 4018
            L + +   HW+ +GV L
Sbjct: 4450 LFTTRHISHWVLQGVCL 4466


>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
            sapiens]
          Length = 4470

 Score = 1980 bits (5129), Expect = 0.0
 Identities = 1223/3695 (33%), Positives = 1948/3695 (52%), Gaps = 202/3695 (5%)

Query: 400  PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458
            P F +R+ LD D + F P L    D  FL + + ++  +  V R+  +L     +K +  
Sbjct: 906  PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 960

Query: 459  TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513
                +  N  +   +E++  +++       E+   +++Y +L T   +  + NFL     
Sbjct: 961  YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1020

Query: 514  --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558
              AE+              +  +  ++I  Y+KL EE+       +  G  +  C    +
Sbjct: 1021 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1080

Query: 559  ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611
            AL+        +    MF+ H    V   L D   F ++A   L+ P    +   L+E+ 
Sbjct: 1081 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1135

Query: 612  AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671
             ++ KV+       +      K  +  L  Y    P ++ L       +    +      
Sbjct: 1136 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1194

Query: 672  KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGD---LQDVQRYLKKAQIL 725
            K+    ++  +   L+ +C++F  +   + ++   E  +SF D    + + +  K    +
Sbjct: 1195 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAM 1254

Query: 726  NGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTE 785
             G ++  +     F      +  L + + + + +++       L++  V  +++   W  
Sbjct: 1255 EGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKT 1307

Query: 786  GPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVIC 845
              +  +N +Q++ D   + + +  L+K        + +   V++ +   +     +  + 
Sbjct: 1308 TKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQ 1363

Query: 846  NPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAM 905
            NP +R RHW+ +        + S+++T++  L +NL  Y D    I + A KE  +EK +
Sbjct: 1364 NPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVL 1423

Query: 906  EKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMRE 965
            + + + W  +EF    +  TGT +L S + +   L+D+ ++ Q +  S ++  + K++  
Sbjct: 1424 KALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTS 1483

Query: 966  WEGKLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSV 1024
            W+ KL     ++  W +VQ TW +LE IF  S DI +Q+P + +RF  +++ ++ +M   
Sbjct: 1484 WQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDA 1543

Query: 1025 MQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILS 1084
            ++  +V+   +   +  +L+   + L +  K L EYLE KRL FPRF+F+S+ +LL+ILS
Sbjct: 1544 VKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILS 1603

Query: 1085 ETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVE 1141
               DP  V  HL K F+ + K++F        +K   G   +  E +         GQVE
Sbjct: 1604 NGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVE 1663

Query: 1142 KWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPM 1201
             WL  +   M +++     +A   Y +  R  W+ D+P Q  L  +QI+WT EV  A   
Sbjct: 1664 VWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFAR 1723

Query: 1202 GIKALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKN 1257
              +  E  ++  N+    Q++ ++TL+ G L+  +R+ +  +  +DVHARDV++ ++   
Sbjct: 1724 LEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAK 1783

Query: 1258 ISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLF 1315
            +     F W +QLR+ W E   H    + +A ++Y YEYLGN+PRLVITPLTDRCY TL 
Sbjct: 1784 VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLT 1843

Query: 1316 GALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGA 1375
             +LHL +GGAP GPAGTGKTETTKDL +A+     VFNCS+ +DY + G  +KGL   GA
Sbjct: 1844 QSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGA 1903

Query: 1376 WACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYA 1435
            W CFDEFNRI +EVLSV+A Q+  +Q  I A      F G  + L PT  +FITMNPGYA
Sbjct: 1904 WGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYA 1963

Query: 1436 GRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQ 1495
            GR+ELP+NLKALFR  AM+VPD+ +I EI+L + GF+ AR L+ K +  Y LC E LS Q
Sbjct: 1964 GRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQ 2023

Query: 1496 HHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDL 1555
             HYD+G+RA+KSVL  AG+LK   P+  E+ +L+R++ D N+PK ++ DLP+F G+  DL
Sbjct: 2024 DHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDL 2083

Query: 1556 FPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGK 1615
            FP + +P+    +    IK +   + LQ    F  K++Q+ E++ VRH   IVG    GK
Sbjct: 2084 FPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGK 2143

Query: 1616 TSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSF 1675
            +   + L     ++  K +  +       L+PK+VT  +L+G  + V+ EW DG+ +   
Sbjct: 2144 SQVLKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIM 2196

Query: 1676 RAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMD 1735
            R  A+      KW+I DG +D +WIE++NTV+DDNK L L S E I ++  M L+FE   
Sbjct: 2197 RDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISH 2256

Query: 1736 LEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVE 1795
            L  A+PATVSR G++Y+ P  LGW P++ SW+          +K  +M LFD+ +P  ++
Sbjct: 2257 LRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLD 2313

Query: 1796 FIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIW 1855
             +R   K+++P  +  ++++++ L++C +     E  +   + RE Y L    F+F+  W
Sbjct: 2314 KLRFGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFW 2366

Query: 1856 SVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYD 1915
            + G +   D  + +            S    N FK             T+ FP +GTI+D
Sbjct: 2367 AFGGAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFD 2405

Query: 1916 YQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFV 1975
            Y ++     K+ PW  K+      P DV     +V T +TIR    M+LL     P + V
Sbjct: 2406 Y-YIDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLV 2463

Query: 1976 GPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPL 2035
            G  GTGKSV + +  L  LN + Y    + F+  TT+A  Q ++   L+K+    +GPP 
Sbjct: 2464 GNAGTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPG 2522

Query: 2036 GKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPP 2095
             K++V F+DD+NMP  + YG   P  L+RQ +DH +WYD    ++  + + Q +  M P 
Sbjct: 2523 TKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPT 2582

Query: 2096 GGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNG 2155
             G    +  R  RHF +  ++    +++ TI++ ILT HL            +++Q+V  
Sbjct: 2583 SGSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAA 2640

Query: 2156 TMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRV 2215
             + L+++     LPT  K HY+FNLRD S + QG+  S  E  +T   + RLW+HE  RV
Sbjct: 2641 ALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERV 2700

Query: 2216 YYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF-- 2273
            Y D+++D  D+  L        + +    F +L   L F           +  +FC F  
Sbjct: 2701 YGDKMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQ 2746

Query: 2274 --HDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILK 2331
               DPK     Y  + D+  L  ++   L+ YN ++   MNLVLF  A+ HI RI+RIL+
Sbjct: 2747 GIGDPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILE 2800

Query: 2332 QPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGE 2391
             PR +ALLVGVGGSG+QS++RLAA+++   VFQ+ + KGY   +   DL     K A   
Sbjct: 2801 SPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2860

Query: 2392 MQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTD 2451
            +  VFL TD+Q+ EE FL  +++LL +GEIP LF  DE + I   M    R + K+   +
Sbjct: 2861 VPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMN 2916

Query: 2452 GSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQA 2511
             +    +  FI+  R QL V+L  SP+G   R R RKFPA+VNC  IDWF  WPEDAL +
Sbjct: 2917 DTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVS 2976

Query: 2512 VASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFK 2571
            V++RFLEE E    I+          HT+  ++S+ +    +RYNY TP ++LE I  ++
Sbjct: 2977 VSARFLEETEGIPVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQ 3036

Query: 2572 LLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIE 2631
             LL KKR+E++   +R E GL KL S +SQV  ++ +L     +LK  ++  D+++ ++ 
Sbjct: 3037 NLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVG 3096

Query: 2632 KESVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQD 2690
             E+ +V+K EK +   E +  E    +   K + C+ DLA A P L +A  ALDTL   +
Sbjct: 3097 IEAEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNN 3155

Query: 2691 ITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-R 2747
            +T +KS  SPP  V  V  A+ IL           T  G KI  +  W  AK ++G +  
Sbjct: 3156 LTELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDT 3204

Query: 2748 FLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVA 2807
            FL SL ++DK++IP A +    K Y  NP F PE IR+ STAA GLC W I +  + +V 
Sbjct: 3205 FLDSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVY 3263

Query: 2808 KIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVD 2867
              VAPK+  L  A  EL  A + L + +  + E+   L+ L    E    +K   + + D
Sbjct: 3264 CDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEAD 3323

Query: 2868 LCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQ 2927
              ++ +  A +L+GGL  E  RW+ +        + L GD+L+ S  V+Y+G FT  YR 
Sbjct: 3324 ATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRN 3383

Query: 2928 N-QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984
                K W          IP ++    +  L +   + TWN  GLPSD  S +N  I+ N 
Sbjct: 3384 ELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNT 3443

Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044
             RWPL++D Q Q  KWIKN  + + L  I+L +  Y+  +E  I  G  +L+EN+GE +D
Sbjct: 3444 ERWPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3502

Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104
            P+L+PLL + T K+G    I++GD  +EY P FR  + TK  NPHY PE   + TL+NF+
Sbjct: 3503 PVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFL 3560

Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164
            +T +G++DQLL  VVA+ERPDLE+ K  L     E K  LKE+ED +L  LS++ GN L 
Sbjct: 3561 VTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLG 3620

Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224
            D   ++ L ++K  A+EI +K   A+ TE KI+  R  YRP A  +S+L+F L DL  I 
Sbjct: 3621 DTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKIN 3680

Query: 3225 PMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSF 3284
            P+YQ+SL  F  +F  +I+ +  +  + +R+  L D  TYS+Y+   R LFE+DKL+F  
Sbjct: 3681 PVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLA 3740

Query: 3285 CLTINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKT 3342
             +T  +L  ++ +N  E  FLL      G+ +P      +L  + W  I  L ++  FK 
Sbjct: 3741 QVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKN 3796

Query: 3343 IRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFII 3402
            +  +       WKK+ +S  P  E+FP+EW++K    Q++ ++RCLRPD++   ++ F+ 
Sbjct: 3797 LDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVE 3855

Query: 3403 NRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSS 3460
             ++G  F+E    + +K++ +S+    + F+LSPG DP+  +       G+     KL +
Sbjct: 3856 EKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHN 3915

Query: 3461 LSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWL 3520
            +SLGQGQ  +A   L+ A ++G WV+LQN HL   W+ TL+K  E  S  S H D+R+++
Sbjct: 3916 VSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGS-HEDYRVFI 3974

Query: 3521 TSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEF 3575
            ++ P+P+      P  +L+N +K+TNE P G+ AN+ ++     +   +    C K  EF
Sbjct: 3975 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCTKEMEF 4031

Query: 3576 KKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRY 3635
            K +L+ LC+FHA+V ERRKFG  GWN  Y FN  DL IS+  L+ +L    ++P++ LRY
Sbjct: 4032 KCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRY 4091

Query: 3636 MTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEY 3695
            + GE  YGG +TDDWDRR  R+ L ++   E++E           + +PP+ D+K Y EY
Sbjct: 4092 LFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEY 4148

Query: 3696 TKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGA---KSSDEVVNEV 3752
                    +P ++G++ NA+I      ++ LF  +L  Q +   +GA    S +E V  V
Sbjct: 4149 IDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAV 4208

Query: 3753 ASDILGKLPNNFDIEAAMRR--YPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAI 3810
              DIL K+P  F++   M +    T Y      V  QE  R N L   +R S   +   +
Sbjct: 4209 LDDILEKIPETFNMAEIMAKAAEKTPYV----VVAFQECERMNILTNEMRRSLKELNLGL 4264

Query: 3811 KGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGP 3869
            KG   ++TD+E++ +++    +P+ W+ ++YPS+  L ++  D L R++ L+ W  +   
Sbjct: 4265 KGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFAL 4324

Query: 3870 PPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHG 3927
            P   WL+GFF  Q+FLT   Q+ ARK   P+D +    EV +   ++   PP +G +++G
Sbjct: 4325 PTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYG 4384

Query: 3928 LFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVL 3987
            LF++GA W+ +   +AE+  K L   +PV+++K      +  +  Y  P+YKT  R    
Sbjct: 4385 LFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR---- 4440

Query: 3988 STTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022
                    +V    L + +    WI   VALL Q+
Sbjct: 4441 -----GPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470


>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
            sapiens]
          Length = 4485

 Score = 1946 bits (5040), Expect = 0.0
 Identities = 1225/3730 (32%), Positives = 1949/3730 (52%), Gaps = 248/3730 (6%)

Query: 400  PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458
            P F +R+ LD D + F P L    D  FL + + ++  +  V R+  +L     +K +  
Sbjct: 897  PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 951

Query: 459  TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513
                +  N  +   +E++  +++       E+   +++Y +L T   +  + NFL     
Sbjct: 952  YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1011

Query: 514  --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558
              AE+              +  +  ++I  Y+KL EE+       +  G  +  C    +
Sbjct: 1012 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1071

Query: 559  ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611
            AL+        +    MF+ H    V   L D   F ++A   L+ P    +   L+E+ 
Sbjct: 1072 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1126

Query: 612  AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671
             ++ KV+       +      K  +  L  Y    P ++ L       +    +      
Sbjct: 1127 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185

Query: 672  KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGK 728
            K+    ++  +   L+ +C++F  +   + ++   E  +SF D  +  + L K  +L G 
Sbjct: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD-PNPYKSLNKVFLLKGI 1244

Query: 729  LDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPY 788
            ++  +     F      +  L + + + + +++       L++  V  +++   W    +
Sbjct: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKTTKW 1297

Query: 789  HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848
              +N +Q++ D   + + +  L+K        + +   V++ +   +     +  + NP 
Sbjct: 1298 KDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPA 1353

Query: 849  LRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKM 908
            +R RHW+ +        + S+++T++  L +NL  Y D    I + A KE  +EK ++ +
Sbjct: 1354 IRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKAL 1413

Query: 909  ITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEG 968
             + W  +EF    +  TGT +L S + +   L+D+ ++ Q +  S ++  + K++  W+ 
Sbjct: 1414 DSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQ 1473

Query: 969  KLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027
            KL     ++  W +VQ TW +LE IF  S DI +Q+P + +RF  +++ ++ +M   ++ 
Sbjct: 1474 KLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKT 1533

Query: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087
             +V+   +   +  +L+   + L +  K L EYLE KRL FPRF+F+S+ +LL+ILS   
Sbjct: 1534 PNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGN 1593

Query: 1088 DPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKWL 1144
            DP  V  HL K F+ + K++F        +K   G   +  E +         GQVE WL
Sbjct: 1594 DPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWL 1653

Query: 1145 VELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK 1204
              +   M +++     +A   Y +  R  W+ D+P       +QI+WT EV  A     +
Sbjct: 1654 NRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYP-------AQIWWTTEVGLAFARLEE 1706

Query: 1205 ALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260
              E  +K  N+    Q++ ++TL+ G L+  +R+ +  +  +DVHARDV++ ++   +  
Sbjct: 1707 GYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VES 1763

Query: 1261 DSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGAL 1318
               F W +QLR+ W E   H    + +A ++Y YEYLGN+PRLVITPLTDRCY TL  +L
Sbjct: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823

Query: 1319 HLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWAC 1378
            HL +GGAP GPAGTGKTETTKDL +A+     VFNCS+ +DY + G  +KGL   GAW C
Sbjct: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883

Query: 1379 FDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRS 1438
            FDEFNRI +EVLSV+A Q+  +Q  I A      F G  + L PT  +FITMNPGYAGR+
Sbjct: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRA 1943

Query: 1439 ELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHY 1498
            ELP+NLKALFR  AM+VPD+ +I EI+L + GF+ AR L+ K +  Y LC E LS Q HY
Sbjct: 1944 ELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHY 2003

Query: 1499 DYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPG 1558
            D+G+RA+KSVL  AG+LK   P+  E+ +L+R++ D N+PK ++ DLP+F G+  DLFP 
Sbjct: 2004 DWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPA 2063

Query: 1559 VKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSA 1618
            + +P+    +    IK +   + LQ    F  K++Q+ E++ VRH   IVG    GK+  
Sbjct: 2064 LDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQV 2123

Query: 1619 YRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAF 1678
             + L     ++  K +  +       L+PK+VT  +L+G  + V+ EW DG+ +   R  
Sbjct: 2124 LKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2176

Query: 1679 ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEV 1738
            A+      KW+I DG +D +WIE++NTV+DDNK L L S E I ++  M L+FE   L  
Sbjct: 2177 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2236

Query: 1739 ASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIR 1798
            A+PATVSR G++Y+ P  LGW P++ SW+          +K  +M LFD+ +P  ++ +R
Sbjct: 2237 ATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLDKLR 2293

Query: 1799 KHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVG 1858
               K+++P  +  ++++++ L++C +     E  +   + RE Y L    F+F+  W+ G
Sbjct: 2294 FGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFWAFG 2346

Query: 1859 ASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQF 1918
             +   D  + +            S    N FK             T+ FP +GTI+DY +
Sbjct: 2347 GAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFDY-Y 2384

Query: 1919 VTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978
            +     K+ PW  K+      P DV     +V T +TIR    M+LL     P + VG  
Sbjct: 2385 IDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2443

Query: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038
            GTGKSV + +  L  LN + Y    + F+  TT+A  Q ++   L+K+    +GPP  K+
Sbjct: 2444 GTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502

Query: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGG 2098
            +V F+DD+NMP  + YG   P  L+RQ +DH +WYD    ++  + + Q +  M P  G 
Sbjct: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562

Query: 2099 RNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMT 2158
               +  R  RHF +  ++    +++ TI++ ILT HL            +++Q+V   + 
Sbjct: 2563 FT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALA 2620

Query: 2159 LYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYD 2218
            L+++     LPT  K HY+FNLRD S + QG+  S  E  +T   + RLW+HE  RVY D
Sbjct: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680

Query: 2219 RLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF----H 2274
            +++D  D+  L        + +    F +L   L F           +  +FC F     
Sbjct: 2681 KMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQGIG 2726

Query: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334
            DPK     Y  + D+  L  ++   L+ YN ++   MNLVLF  A+ HI RI+RIL+ PR
Sbjct: 2727 DPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPR 2780

Query: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394
             +ALLVGVGGSG+QS++RLAA+++   VFQ+ + KGY   +   DL     K A   +  
Sbjct: 2781 GNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPS 2840

Query: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454
            VFL TD+Q+ EE FL  +++LL +GEIP LF  DE + I   M    R + K+   + + 
Sbjct: 2841 VFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMNDTR 2896

Query: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514
               +  FI+  R QL V+L  SP+G   R R RKFPA+VNC  IDWF  WPEDAL +V++
Sbjct: 2897 ETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSA 2956

Query: 2515 RFLEEIE-MSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573
            RFLEE E +  E++          HT+  ++S+ +    +RYNY TP ++LE I  ++ L
Sbjct: 2957 RFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNL 3016

Query: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633
            L KKR+E++   +R E GL KL S +SQV  ++ +L     +LK  ++  D+++ ++  E
Sbjct: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076

Query: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQDIT 2692
            + +V+K EK +   E +  E    +   K + C+ DLA A P L +A  ALDTL   ++T
Sbjct: 3077 AEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLT 3135

Query: 2693 VVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-RFL 2749
             +KS  SPP  V  V  A+ IL           T  G KI  +  W  AK ++G +  FL
Sbjct: 3136 ELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDTFL 3184

Query: 2750 QSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKI 2809
             SL ++DK++IP A +    K Y  NP F PE IR+ STAA GLC W I +  + +V   
Sbjct: 3185 DSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD 3243

Query: 2810 VAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLC 2869
            VAPK+  L  A  EL  A + L + +  + E+   L+ L    E    +K   + + D  
Sbjct: 3244 VAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADAT 3303

Query: 2870 SKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN- 2928
            ++ +  A +L+GGL  E  RW+ +        + L GD+L+ S  V+Y+G FT  YR   
Sbjct: 3304 NRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNEL 3363

Query: 2929 QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARR 2986
              K W          IP ++    +  L +   + TWN  GLPSD  S +N  I+ N  R
Sbjct: 3364 MEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTER 3423

Query: 2987 WPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPI 3046
            WPL++D Q Q  KWIKN  + + L  I+L +  Y+  +E  I  G  +L+EN+GE +DP+
Sbjct: 3424 WPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPV 3482

Query: 3047 LEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMIT 3106
            L+PLL + T K+G    I++GD  +EY P FR  + TK  NPHY PE   + TL+NF++T
Sbjct: 3483 LDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540

Query: 3107 PEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDE 3166
             +G++DQLL  VVA+ERPDLE+ K  L     E K  LKE+ED +L  LS++ GN L D 
Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600

Query: 3167 TAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPM 3226
              ++ L ++K  A+EI +K   A+ TE KI+  R  YRP A  +S+L+F L DL  I P+
Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660

Query: 3227 YQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCL 3286
            YQ+SL  F  +F  +I+ +  +  + +R+  L D  TYS+Y+   R LFE+DKL+F   +
Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720

Query: 3287 TINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIR 3344
            T  +L  ++ +N  E  FLL      G+ +P      +L  + W  I  L ++  FK + 
Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKNLD 3776

Query: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404
             +       WKK+ +S  P  E+FP+EW++K    Q++ ++RCLRPD++   ++ F+  +
Sbjct: 3777 SDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEK 3835

Query: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSSLS 3462
            +G  F+E    + +K++ +S+    + F+LSPG DP+  +       G+     KL ++S
Sbjct: 3836 MGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVS 3895

Query: 3463 LGQGQGPIAMKMLEKAVKEGTWVVLQ--------NCHLATSWMPTLEKVCEELSPESTHP 3514
            LGQGQ  +A   L+ A ++G WV+LQ        N HL   W+ TL+K  E  S  S H 
Sbjct: 3896 LGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HE 3954

Query: 3515 DFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSC 3569
            D+R+++++ P+P+      P  +L+N +K+TNE P G+ AN+ ++     +   +    C
Sbjct: 3955 DYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMC 4011

Query: 3570 KKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELP 3629
             K  EFK +L+ LC+FHA+V ERRKFG  GWN  Y FN  DL IS+  L+ +L    ++P
Sbjct: 4012 TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVP 4071

Query: 3630 YEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDH 3689
            ++ LRY+ GE  YGG +TDDWDRR  R+ L ++   E++E           + +PP+ D+
Sbjct: 4072 WDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDY 4128

Query: 3690 KSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDE 3747
            K Y EY        +P ++G++ NA+I      ++ LF  +L  Q +   +GAG   S E
Sbjct: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188

Query: 3748 ------------------------------VVNEVASDILGKLPNNFDIEAAMRR--YPT 3775
                                           V  V  DIL K+P  F++   M +    T
Sbjct: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248

Query: 3776 TYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEM 3835
             Y      V  QE  R N L   +R S   +   +KG   ++TD+E++ +++    +P+ 
Sbjct: 4249 PYV----VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDT 4304

Query: 3836 WMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYAR 3894
            W+ ++YPS+  L ++  D L R++ L+ W  +   P   WL+GFF  Q+FLT   Q+ AR
Sbjct: 4305 WVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMAR 4364

Query: 3895 KYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYD 3952
            K   P+D +    EV +   ++   PP +G +++GLF++GA W+ +   +AE+  K L  
Sbjct: 4365 KNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTP 4424

Query: 3953 TVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWI 4012
             +PV+++K      +  +  Y  P+YKT  R            +V    L + +    WI
Sbjct: 4425 AMPVIFIKAIPVDRMETKNIYECPVYKTRIR---------GPTYVWTFNLKTKEKAAKWI 4475

Query: 4013 GRGVALLCQL 4022
               VALL Q+
Sbjct: 4476 LAAVALLLQV 4485


>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
            sapiens]
          Length = 4485

 Score = 1945 bits (5039), Expect = 0.0
 Identities = 1224/3730 (32%), Positives = 1949/3730 (52%), Gaps = 248/3730 (6%)

Query: 400  PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458
            P F +R+ LD D + F P L    D  FL + + ++  +  V R+  +L     +K +  
Sbjct: 897  PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 951

Query: 459  TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513
                +  N  +   +E++  +++       E+   +++Y +L T   +  + NFL     
Sbjct: 952  YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1011

Query: 514  --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558
              AE+              +  +  ++I  Y+KL EE+       +  G  +  C    +
Sbjct: 1012 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1071

Query: 559  ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611
            AL+        +    MF+ H    V   L D   F ++A   L+ P    +   L+E+ 
Sbjct: 1072 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1126

Query: 612  AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671
             ++ KV+       +      K  +  L  Y    P ++ L       +    +      
Sbjct: 1127 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185

Query: 672  KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGK 728
            K+    ++  +   L+ +C++F  +   + ++   E  +SF D  +  + L K  +L G 
Sbjct: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD-PNPYKSLNKVFLLKGI 1244

Query: 729  LDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPY 788
            ++  +     F      +  L + + + + +++       L++  V  +++   W    +
Sbjct: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKTTKW 1297

Query: 789  HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848
              +N +Q++ D   + + +  L+K        + +   V++ +   +     +  + NP 
Sbjct: 1298 KDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPA 1353

Query: 849  LRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKM 908
            +R RHW+ +        + S+++T++  L +NL  Y D    I + A KE  +EK ++ +
Sbjct: 1354 IRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKAL 1413

Query: 909  ITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEG 968
             + W  +EF    +  TGT +L S + +   L+D+ ++ Q +  S ++  + K++  W+ 
Sbjct: 1414 DSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQ 1473

Query: 969  KLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027
            KL     ++  W +VQ TW +LE IF  S DI +Q+P + +RF  +++ ++ +M   ++ 
Sbjct: 1474 KLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKT 1533

Query: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087
             +V+   +   +  +L+   + L +  K L EYLE KRL FPRF+F+S+ +LL+ILS   
Sbjct: 1534 PNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGN 1593

Query: 1088 DPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKWL 1144
            DP  V  HL K F+ + K++F        +K   G   +  E +         GQVE WL
Sbjct: 1594 DPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWL 1653

Query: 1145 VELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK 1204
              +   M +++     +A   Y +  R  W+ D+P       +QI+WT EV  A     +
Sbjct: 1654 NRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYP-------AQIWWTTEVGLAFARLEE 1706

Query: 1205 ALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260
              E  ++  N+    Q++ ++TL+ G L+  +R+ +  +  +DVHARDV++ ++   +  
Sbjct: 1707 GYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMI---VES 1763

Query: 1261 DSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGAL 1318
               F W +QLR+ W E   H    + +A ++Y YEYLGN+PRLVITPLTDRCY TL  +L
Sbjct: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823

Query: 1319 HLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWAC 1378
            HL +GGAP GPAGTGKTETTKDL +A+     VFNCS+ +DY + G  +KGL   GAW C
Sbjct: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883

Query: 1379 FDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRS 1438
            FDEFNRI +EVLSV+A Q+  +Q  I A      F G  + L PT  +FITMNPGYAGR+
Sbjct: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRA 1943

Query: 1439 ELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHY 1498
            ELP+NLKALFR  AM+VPD+ +I EI+L + GF+ AR L+ K +  Y LC E LS Q HY
Sbjct: 1944 ELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHY 2003

Query: 1499 DYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPG 1558
            D+G+RA+KSVL  AG+LK   P+  E+ +L+R++ D N+PK ++ DLP+F G+  DLFP 
Sbjct: 2004 DWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPA 2063

Query: 1559 VKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSA 1618
            + +P+    +    IK +   + LQ    F  K++Q+ E++ VRH   IVG    GK+  
Sbjct: 2064 LDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQV 2123

Query: 1619 YRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAF 1678
             + L     ++  K +  +       L+PK+VT  +L+G  + V+ EW DG+ +   R  
Sbjct: 2124 LKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2176

Query: 1679 ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEV 1738
            A+      KW+I DG +D +WIE++NTV+DDNK L L S E I ++  M L+FE   L  
Sbjct: 2177 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2236

Query: 1739 ASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIR 1798
            A+PATVSR G++Y+ P  LGW P++ SW+          +K  +M LFD+ +P  ++ +R
Sbjct: 2237 ATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLDKLR 2293

Query: 1799 KHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVG 1858
               K+++P  +  ++++++ L++C +     E  +   + RE Y L    F+F+  W+ G
Sbjct: 2294 FGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFWAFG 2346

Query: 1859 ASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQF 1918
             +   D  + +            S    N FK             T+ FP +GTI+DY +
Sbjct: 2347 GAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFDY-Y 2384

Query: 1919 VTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978
            +     K+ PW  K+      P DV     +V T +TIR    M+LL     P + VG  
Sbjct: 2385 IDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2443

Query: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038
            GTGKSV + +  L  LN + Y    + F+  TT+A  Q ++   L+K+    +GPP  K+
Sbjct: 2444 GTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502

Query: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGG 2098
            +V F+DD+NMP  + YG   P  L+RQ +DH +WYD    ++  + + Q +  M P  G 
Sbjct: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562

Query: 2099 RNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMT 2158
               +  R  RHF +  ++    +++ TI++ ILT HL            +++Q+V   + 
Sbjct: 2563 FT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALA 2620

Query: 2159 LYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYD 2218
            L+++     LPT  K HY+FNLRD S + QG+  S  E  +T   + RLW+HE  RVY D
Sbjct: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680

Query: 2219 RLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF----H 2274
            +++D  D+  L        + +    F +L   L F           +  +FC F     
Sbjct: 2681 KMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQGIG 2726

Query: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334
            DPK     Y  + D+  L  ++   L+ YN ++   MNLVLF  A+ HI RI+RIL+ PR
Sbjct: 2727 DPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPR 2780

Query: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394
             +ALLVGVGGSG+QS++RLAA+++   VFQ+ + KGY   +   DL     K A   +  
Sbjct: 2781 GNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPS 2840

Query: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454
            VFL TD+Q+ EE FL  +++LL +GEIP LF  DE + I   M    R + K+   + + 
Sbjct: 2841 VFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMNDTR 2896

Query: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514
               +  FI+  R QL V+L  SP+G   R R RKFPA+VNC  IDWF  WPEDAL +V++
Sbjct: 2897 ETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSA 2956

Query: 2515 RFLEEIE-MSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573
            RFLEE E +  E++          HT+  ++S+ +    +RYNY TP ++LE I  ++ L
Sbjct: 2957 RFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNL 3016

Query: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633
            L KKR+E++   +R E GL KL S +SQV  ++ +L     +LK  ++  D+++ ++  E
Sbjct: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076

Query: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQDIT 2692
            + +V+K EK +   E +  E    +   K + C+ DLA A P L +A  ALDTL   ++T
Sbjct: 3077 AEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLT 3135

Query: 2693 VVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-RFL 2749
             +KS  SPP  V  V  A+ IL           T  G KI  +  W  AK ++G +  FL
Sbjct: 3136 ELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDTFL 3184

Query: 2750 QSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKI 2809
             SL ++DK++IP A +    K Y  NP F PE IR+ STAA GLC W I +  + +V   
Sbjct: 3185 DSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD 3243

Query: 2810 VAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLC 2869
            VAPK+  L  A  EL  A + L + +  + E+   L+ L    E    +K   + + D  
Sbjct: 3244 VAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADAT 3303

Query: 2870 SKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN- 2928
            ++ +  A +L+GGL  E  RW+ +        + L GD+L+ S  V+Y+G FT  YR   
Sbjct: 3304 NRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNEL 3363

Query: 2929 QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARR 2986
              K W          IP ++    +  L +   + TWN  GLPSD  S +N  I+ N  R
Sbjct: 3364 MEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTER 3423

Query: 2987 WPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPI 3046
            WPL++D Q Q  KWIKN  + + L  I+L +  Y+  +E  I  G  +L+EN+GE +DP+
Sbjct: 3424 WPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPV 3482

Query: 3047 LEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMIT 3106
            L+PLL + T K+G    I++GD  +EY P FR  + TK  NPHY PE   + TL+NF++T
Sbjct: 3483 LDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540

Query: 3107 PEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDE 3166
             +G++DQLL  VVA+ERPDLE+ K  L     E K  LKE+ED +L  LS++ GN L D 
Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600

Query: 3167 TAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPM 3226
              ++ L ++K  A+EI +K   A+ TE KI+  R  YRP A  +S+L+F L DL  I P+
Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660

Query: 3227 YQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCL 3286
            YQ+SL  F  +F  +I+ +  +  + +R+  L D  TYS+Y+   R LFE+DKL+F   +
Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720

Query: 3287 TINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIR 3344
            T  +L  ++ +N  E  FLL      G+ +P      +L  + W  I  L ++  FK + 
Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKNLD 3776

Query: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404
             +       WKK+ +S  P  E+FP+EW++K    Q++ ++RCLRPD++   ++ F+  +
Sbjct: 3777 SDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEK 3835

Query: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSSLS 3462
            +G  F+E    + +K++ +S+    + F+LSPG DP+  +       G+     KL ++S
Sbjct: 3836 MGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVS 3895

Query: 3463 LGQGQGPIAMKMLEKAVKEGTWVVLQ--------NCHLATSWMPTLEKVCEELSPESTHP 3514
            LGQGQ  +A   L+ A ++G WV+LQ        N HL   W+ TL+K  E  S  S H 
Sbjct: 3896 LGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGS-HE 3954

Query: 3515 DFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSC 3569
            D+R+++++ P+P+      P  +L+N +K+TNE P G+ AN+ ++     +   +    C
Sbjct: 3955 DYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMC 4011

Query: 3570 KKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELP 3629
             K  EFK +L+ LC+FHA+V ERRKFG  GWN  Y FN  DL IS+  L+ +L    ++P
Sbjct: 4012 TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVP 4071

Query: 3630 YEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDH 3689
            ++ LRY+ GE  YGG +TDDWDRR  R+ L ++   E++E           + +PP+ D+
Sbjct: 4072 WDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDY 4128

Query: 3690 KSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDE 3747
            K Y EY        +P ++G++ NA+I      ++ LF  +L  Q +   +GAG   S E
Sbjct: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188

Query: 3748 ------------------------------VVNEVASDILGKLPNNFDIEAAMRR--YPT 3775
                                           V  V  DIL K+P  F++   M +    T
Sbjct: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248

Query: 3776 TYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEM 3835
             Y      V  QE  R N L   +R S   +   +KG   ++TD+E++ +++    +P+ 
Sbjct: 4249 PYV----VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDT 4304

Query: 3836 WMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYAR 3894
            W+ ++YPS+  L ++  D L R++ L+ W  +   P   WL+GFF  Q+FLT   Q+ AR
Sbjct: 4305 WVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMAR 4364

Query: 3895 KYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYD 3952
            K   P+D +    EV +   ++   PP +G +++GLF++GA W+ +   +AE+  K L  
Sbjct: 4365 KNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTP 4424

Query: 3953 TVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWI 4012
             +PV+++K      +  +  Y  P+YKT  R            +V    L + +    WI
Sbjct: 4425 AMPVIFIKAIPVDRMETKNIYECPVYKTRIR---------GPTYVWTFNLKTKEKAAKWI 4475

Query: 4013 GRGVALLCQL 4022
               VALL Q+
Sbjct: 4476 LAAVALLLQV 4485


>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
          Length = 4486

 Score = 1941 bits (5029), Expect = 0.0
 Identities = 1194/3573 (33%), Positives = 1893/3573 (52%), Gaps = 200/3573 (5%)

Query: 509  VDNFLAENHSYEKIIDEICKYQ--KLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADI 566
            +  F  +  SYE + +E+C+ +  K+ +      I+  +  +           ++KR  +
Sbjct: 1055 LSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLN---------IIKRWSL 1105

Query: 567  ICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAE---LMEMKAYIQKVEVTDMI 623
            +  + L     DH   +    D F + +E  L       +   L+E+  ++  V+     
Sbjct: 1106 LFKQHLV----DHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQS- 1160

Query: 624  ELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKI---IKEKIEQ 680
              ++     K  +  L  Y      +  L  +VF+    + E +   +K+   +K+++  
Sbjct: 1161 NTDEMFEPLKQTIELLKTY------EQELPETVFKQLEELPEKWNNIKKVAITVKQQVAP 1214

Query: 681  YQEG----LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGKLDLAAD 734
             Q      L+ RC  F  E + + +Q   E  + F  +   Q            LD    
Sbjct: 1215 LQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQM-----------LDARHI 1263

Query: 735  KIEQFNAEEEAFGWLPSV-------YPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGP 787
            +I+Q  +   +     S+       Y Q ++ +  +     L++T    +S+  AW   P
Sbjct: 1264 EIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTP 1323

Query: 788  YHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNP 847
            +  +N + +E +   + R +  L+K       A      + S V +    +  +  + NP
Sbjct: 1324 WRNINVEAMELECKQFARHIRNLDKEVR----AWDAFTGLESTVWNTLSSLRAVAELQNP 1379

Query: 848  GLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEK 907
             +R RHW  +    G       D+T++  L + L  Y D   GI + A+KE  +EK +++
Sbjct: 1380 AIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKE 1439

Query: 908  MITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWE 967
            + T W  +EF    +  T   +L S +++  +L+D+ ++ Q +  S ++  + +++  W+
Sbjct: 1440 LQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQ 1499

Query: 968  GKLLLLQEILDEWLKVQATWLYLEPIFS-SPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQ 1026
             KL  +  ++  W +VQ TW +LE IF+ S DI +Q+P++ +RF  +D  ++++     +
Sbjct: 1500 KKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQK 1559

Query: 1027 DKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSET 1086
              +V+       + E+L+     L L  K L EYL+ KRL FPRF+FLS+ +LL+ILS  
Sbjct: 1560 IPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNG 1619

Query: 1087 KDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKW 1143
              P +VQ HL K F+ +AK+ F         K+S G   +  E +         GQVE W
Sbjct: 1620 TAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIW 1679

Query: 1144 LVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTA---IP 1200
            L  +   M  ++     +   AY +  R  W+ D P Q  L  +QI+WT EV  A   + 
Sbjct: 1680 LNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLE 1739

Query: 1201 MGIK-ALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNIS 1259
             G + A++ Y K    Q+  ++T++ G+LS  +R  +  +  +DVHARDV++ ++ + + 
Sbjct: 1740 EGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVD 1799

Query: 1260 DDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGA 1317
            +   F WLSQLR+ W +   H    + +A   Y YEYLGN+PRLVITPLTDRCY TL  +
Sbjct: 1800 NAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQS 1859

Query: 1318 LHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWA 1377
            LHL + GAP GPAGTGKTETTKDL +A+     VFNCS+ +DY + G  +KGL   GAW 
Sbjct: 1860 LHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWG 1919

Query: 1378 CFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGR 1437
            CFDEFNRI +EVLSVVA Q+ +IQ  I        F G E+ L+P+  +FITMNPGYAGR
Sbjct: 1920 CFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGR 1979

Query: 1438 SELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHH 1497
            +ELP+NLK+LFR  AM+VPD+ +I EI+L + GF+ A+ L+ K +  Y+LC E LS Q H
Sbjct: 1980 TELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDH 2039

Query: 1498 YDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFP 1557
            YD+G+RA+KSVL  AG+LK   P+  E+ +L+RS+ D N+PK ++ D+P+F G+  DLFP
Sbjct: 2040 YDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFP 2099

Query: 1558 GVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTS 1617
             + +P+    +  A ++     + LQ    F  K++Q+ E++ VRH   +VG    GK+ 
Sbjct: 2100 ALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQ 2159

Query: 1618 AYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRA 1677
              R L           +M+   V  T LNPK+VT  +L+G  +  + EW DG+ +   R 
Sbjct: 2160 VLRSLHKTYQ------IMKRRPVW-TDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRE 2212

Query: 1678 FASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLE 1737
             A+      KW++ DG +D +WIE++NTV+DDNK L L S E I ++P M L+FE   L 
Sbjct: 2213 LANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLR 2272

Query: 1738 VASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFI 1797
             A+PATVSR G++Y+ P  LGW P + SW+          ++  +  LFD+ +P  ++ +
Sbjct: 2273 TATPATVSRAGILYINPADLGWNPPVSSWIEKREIQT---ERANLTILFDKYLPTCLDTL 2329

Query: 1798 RKHTKELSPTSDTNLVRSLMNLIDCFM---DDFADEVKLKERNDRETYSLLEGIFLFSLI 1854
            R   K++ P  + ++V+ + +L++C +   D  AD  K           + E  F+F+ I
Sbjct: 2330 RTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPK----------EIYEHYFVFAAI 2379

Query: 1855 WSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIY 1914
            W+ G +   D  + +         +  S      FK             TV FP +GTI+
Sbjct: 2380 WAFGGAMVQDQLVDY--------RAEFSKWWLTEFK-------------TVKFPSQGTIF 2418

Query: 1915 DYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIF 1974
            DY ++     K+EPW K + +    P ++     +V T +TIR    ME L   Q+P + 
Sbjct: 2419 DY-YIDPETKKFEPWSKLVPQFEFDP-EMPLQACLVHTSETIRVCYFMERLMARQRPVML 2476

Query: 1975 VGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPP 2034
            VG  GTGKSV +    L  L+ E Y    + F+  TT+A  Q ++   L+K+    +GPP
Sbjct: 2477 VGTAGTGKSV-LVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPP 2535

Query: 2035 LGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGP 2094
              K+++ F+DD+NMP  + YG   P  ++RQ LD+ +WYD    S+ ++ ++Q +  M P
Sbjct: 2536 GNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNP 2595

Query: 2095 PGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVN 2154
              G    + PR  RHF++  ++     ++ +I+S ILT HL++   FP         +++
Sbjct: 2596 TAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKL-GNFPASLQKSIPPLID 2653

Query: 2155 GTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLR 2214
              +  +++     LPT  K HY+FNLRDF+ + QG+  S  E  ++T  + RL++HE  R
Sbjct: 2654 LALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNR 2713

Query: 2215 VYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFH 2274
            VY D++++  D   L + IQ  +    ++D  +  ++    N            ++C F 
Sbjct: 2714 VYRDKMVEEKDFD-LFDKIQTEVLKKTFDDIEDPVEQTQSPN------------LYCHFA 2760

Query: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334
            +   E   Y  +   + L   +   LE +N ++   M+LVLF  A+ H+  I+RIL+ PR
Sbjct: 2761 NGIGE-PKYMPVQSWELLTQTLVEALENHNEVN-TVMDLVLFEDAMRHVCHINRILESPR 2818

Query: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394
             +ALLVGVGGSG+QS+TRLAA ++   VFQ+ + KGY   ++  DL  +  K     +  
Sbjct: 2819 GNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNT 2878

Query: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454
            VFL TD Q+ +E FL  +++LL +GEIP+L++ DE + I   +R   + +      +   
Sbjct: 2879 VFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNREN-- 2936

Query: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514
               +  FID  R QL V L  SP+G+  R R RKFPA+VNC  I WF  WP+ AL++V+ 
Sbjct: 2937 --CWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSL 2994

Query: 2515 RFLEEIEMSEEIRDGCIDMCKSF-HTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573
            RFL+  E  E      I    +F HTS    S+S+    QRYNY TP S+LE I  ++ L
Sbjct: 2995 RFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSL 3054

Query: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633
            L + R E+    +R E GL KL S S+QV  ++ +L A   +LK  +++ D+++ ++  E
Sbjct: 3055 LHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVE 3114

Query: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITV 2693
            + +V++ + +   +E       +  K  + +C+ DLA A P L +A AAL+TL   ++T 
Sbjct: 3115 TDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTE 3174

Query: 2694 VKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDM-RFLQSL 2752
            +KS  SPP  V  V  A+ +L          P G   K +  W  AK  +  +  FL SL
Sbjct: 3175 LKSFGSPPLAVSNVSAAVMVLMA--------PRGRVPK-DRSWKAAKVTMAKVDGFLDSL 3225

Query: 2753 HEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAP 2812
              ++K+NI    +  IR  Y+ +P+F PE +   S AA GLC WVI +  + +V   V P
Sbjct: 3226 INFNKENIHENCLKAIRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEP 3284

Query: 2813 KKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKK 2872
            K+  L  A  +L  A + L   +A +  + + LA+L    E     K   + + ++ +  
Sbjct: 3285 KRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVT 3344

Query: 2873 LERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN-QTK 2931
            +  A +L+GGL  E  RW+       Q    L GDIL+ +  ++YLG FT  YRQ+   +
Sbjct: 3345 ISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDR 3404

Query: 2932 EWTTLCK--GRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPL 2989
             W          IP +     +  L +   +  W   GLP+D  S++N  I++N  RWPL
Sbjct: 3405 TWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPL 3464

Query: 2990 MIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEP 3049
            M+DPQ Q  KWIKN +    L V ++ +  Y++ +E  ++ G  VL+EN+ E +DP+L P
Sbjct: 3465 MVDPQLQGIKWIKN-KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGP 3523

Query: 3050 LLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEG 3109
            LL ++  K+G    I++GD   EY P FR  + TKL NPHY PE   + TL+NF +T +G
Sbjct: 3524 LLGREVIKKG--RFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDG 3581

Query: 3110 MQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAI 3169
            ++DQLL  VV+ ERPDLE+ K  L  Q    K  LK +ED +L  LSS+ GN L +   +
Sbjct: 3582 LEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLV 3641

Query: 3170 KILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQY 3229
            + L  +K  A E+ +K + A+ TE KI+  R  YRP A  +S+L+F + DL+ I PMYQ+
Sbjct: 3642 ENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQF 3701

Query: 3230 SLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTIN 3289
            SL  F  +F  ++E +   E L +R+  L D  T+S+Y    R LFE DKL +   LT  
Sbjct: 3702 SLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQ 3761

Query: 3290 LLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMR 3349
            +LL  R +N  E  FLL   +      A+   +L  ++W  +  L  +  F  + R+   
Sbjct: 3762 ILLMNREVNAVELDFLLRSPV--QTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEG 3819

Query: 3350 LKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAF 3409
                WKK  +S  P  E  P+EW++K    QR+ ++R +RPD++   L++F+  +LG  +
Sbjct: 3820 SAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKY 3878

Query: 3410 IEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQG------YGGSKLSSLSL 3463
            +     D A +F +S    P+ F+LSPG DP    LK  + QG      +      ++SL
Sbjct: 3879 VVGRALDFATSFEESGPATPMFFILSPGVDP----LKDVESQGRKLGYTFNNQNFHNVSL 3934

Query: 3464 GQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSY 3523
            GQGQ  +A   L+ A K+G WV+LQN HL   W+ TLEK  EE S E++HP+FR+++++ 
Sbjct: 3935 GQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENSHPEFRVFMSAE 3993

Query: 3524 PSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKL 3578
            P+P+      P  +L+N +K+TNE P G+ AN+ ++  +D  +  +    C +  EFK +
Sbjct: 3994 PAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA--LDNFTQ-DTLEMCSRETEFKSI 4050

Query: 3579 LYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTG 3638
            L+ LC+FHA+V ERRKFGP GWN  Y FN  DL ISV  L+ FL    ++PY+ LRY+ G
Sbjct: 4051 LFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFG 4110

Query: 3639 ECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKT 3698
            E  YGG +TDDWDRR  R+ L +F  PE++E    +   +  + +P + D+  Y +Y   
Sbjct: 4111 EIMYGGHITDDWDRRLCRTYLGEFIRPEMLEG---ELSLAPGFPLPGNMDYNGYHQYIDA 4167

Query: 3699 LPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSA----GAGAKSSDEVVNEVAS 3754
                 +P ++G++ NA+I      ++ LF  +L  Q R +    GAGA + +E V  +  
Sbjct: 4168 ELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGA-TREEKVKALLE 4226

Query: 3755 DILGKLPNNFDIEAAMRRYP--TTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKG 3812
            +IL ++ + F+I   M +    T Y      V  QE GR N L + I+ S   ++  +KG
Sbjct: 4227 EILERVTDEFNIPELMAKVEERTPYI----VVAFQECGRMNILTREIQRSLRELELGLKG 4282

Query: 3813 LAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWY-EVGPPP 3871
               M++ +E + +++    +PE W  ++YPS   L ++  D L R+K L+ W  +   P 
Sbjct: 4283 ELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPS 4342

Query: 3872 VFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLF 3929
              WL+GFF  Q+FLT   Q+ ARK   P+D +    ++ +   +E++ PP +G +IHGLF
Sbjct: 4343 TVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLF 4402

Query: 3930 LDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLST 3989
            ++GA W+ +   + E+  K L   +PVM++K         R  Y  P+YKTS+R      
Sbjct: 4403 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR------ 4456

Query: 3990 TGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022
                  +V    L + +    W+  GVALL Q+
Sbjct: 4457 ---GPTYVWTFNLKTKENPSKWVLAGVALLLQI 4486


>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
          Length = 4624

 Score = 1918 bits (4968), Expect = 0.0
 Identities = 1213/3682 (32%), Positives = 1907/3682 (51%), Gaps = 202/3682 (5%)

Query: 409  DNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEI 468
            D+D    E EL D ++I          +V+    V+TK Y K  S++K       +L+ I
Sbjct: 1076 DSDVEMGENELQDTLEI---------ASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTI 1126

Query: 469  VDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICK 528
            +++ K   KEVI          +  + +Y+ +  +  E  +  F+ ++    +   +I  
Sbjct: 1127 INSTK---KEVITS--------MDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILY 1175

Query: 529  YQKLIEEI----QYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNT 584
            +Q L +EI    +Y  + +I L  +    +  + A  K   ++ G+   K +R   E   
Sbjct: 1176 FQNLEQEINAEPEYVCVGSIAL--YTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIF 1233

Query: 585  RLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVN 644
             L +EF     K L+ P    + + +     K    + I ++ ++   +   A L  Y  
Sbjct: 1234 MLIEEFN----KKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGL 1289

Query: 645  FSPADM--RLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQ 702
                +   +++   + W   +    E     ++ K+   Q   K   +  +  +E + + 
Sbjct: 1290 LIAREEIDKVDTLHYAWEKLLARAGE-----VQNKLVSLQPSFK---KELISAVEVFLQD 1341

Query: 703  SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQ-------FNAEEEAFGWLPSVYPQ 755
              +FY   DL        K Q  + +L +  ++ +        +   EE FG   + YPQ
Sbjct: 1342 CHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQ 1401

Query: 756  RKKIQDGLNPYLR---LYETAVEFSSNYR--AWTEGPYHKVNPDQVEADIGNYWRGLYKL 810
              +I+  LN   +   LY + +E  ++Y    W+E    K+N + +E     +     KL
Sbjct: 1402 LLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLE-----FQNRCRKL 1456

Query: 811  EKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDD 870
             +   D    L + KK+   ++DF +  PL++ + +  +  RHWE ++ + G+ L   ++
Sbjct: 1457 PRALKDWQAFLDL-KKI---IDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNE 1512

Query: 871  S-TVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFI 929
            S  + + ++  L  Y +  E I  +A KE  +E+ ++++I EWD   F   S++  G  +
Sbjct: 1513 SFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELL 1572

Query: 930  LA--SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATW 987
            L   S  EI   ++D ++   ++  + +  P++ Q+++W   L    +I++ W+ VQ  W
Sbjct: 1573 LRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLW 1632

Query: 988  LYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML-ERLKKS 1046
            +YLE +F   DI  Q+P+E +RF+ +DK+W  IM    +   V+     D  L + L   
Sbjct: 1633 IYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHL 1692

Query: 1047 NELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKV 1106
             + LE+  K L  YLEKKRL FPRFFF+S+  LLEIL +  D   +Q HL   F+ I  V
Sbjct: 1693 LDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSV 1752

Query: 1107 EFTETL--DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDAT- 1163
            +F E +   I  + S EGE +EL + +    A G VE WL  L     +S+H V   A  
Sbjct: 1753 KFHEKIYDRILSISSQEGETIELDKPVM---AEGNVEVWLNSLLEESQSSLHLVIRQAAA 1809

Query: 1164 -FAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAI---PMGIKALEQYLKTCNRQIDD 1219
                T ++   ++  +P Q  L   Q+ WT++ + A+       K +++  +     ++ 
Sbjct: 1810 NIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNT 1869

Query: 1220 IVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENH- 1278
            ++ +    LS   RV    L+ + VH RD+   L   +I    DFEWL Q R+Y+ E+  
Sbjct: 1870 LIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSD 1929

Query: 1279 -LETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTET 1337
             +   + +    Y  E+LG + RLVITPLTDRCY TL  AL + +GGAP GPAGTGKTET
Sbjct: 1930 KMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTET 1989

Query: 1338 TKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQI 1397
            TKD+ + + K  VVFNCSD +D+  LG+ FKGL   G+W CFDEFNRIDL VLSV AQQI
Sbjct: 1990 TKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQI 2049

Query: 1398 LTIQRGINAGADILMF-EGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVP 1456
              I           +F +G  + ++P   +F+TMNPGYAGR ELP+NLK  FR+VAMMVP
Sbjct: 2050 SIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVP 2109

Query: 1457 DYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLK 1516
            D  +I  + L SCGF+    L+ K    Y+LC EQLS Q HYD+G+R + SVL   G  K
Sbjct: 2110 DRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAK 2169

Query: 1517 LKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDN 1576
               P + E  +++R + D+NL K +  D PLF  +  DLFP + L K  Y +L AAI   
Sbjct: 2170 RANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQ 2229

Query: 1577 CASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLME 1636
                 L     +  K++Q++E   VRHG M +G    GKT+    L  A+ D C K   E
Sbjct: 2230 VEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTD-CGKPHRE 2288

Query: 1637 ENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVD 1696
                    +NPK++T  Q++G+ D  +++W+DG+ +  +R    +   +  W+I DGPVD
Sbjct: 2289 MR------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVD 2342

Query: 1697 AVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHM 1756
            A+WIEN+N+VLDDNK L L +G+ I M+P   +IFEP +++ ASPATVSR GM++M   +
Sbjct: 2343 AIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSI 2402

Query: 1757 LGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSL 1816
            L W P++  ++       + I ++     F  +    ++ +    + L     T  +  L
Sbjct: 2403 LDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINML 2462

Query: 1817 MNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILREL 1876
              LI            LKE+    + + L  +F+F+L+WS GA+   D R +    LR  
Sbjct: 2463 QGLIP-----------LKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLR-- 2509

Query: 1877 MESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKE- 1935
                              +  T +  L  P     T +DY    +G   W  W  + +E 
Sbjct: 2510 ------------------SRPTGTLELPPPAGPGDTAFDYYVAPDGT--WTHWNTRTQEY 2549

Query: 1936 APPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLN 1995
              P      +  I+VP +D +R   L++ +    K  + +G  GT K+V I  F+ ++ +
Sbjct: 2550 LYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFM-SKYD 2608

Query: 1996 KEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYG 2055
             E +    +NFS+ TT    Q  + S +DKR    +GPP GK+M VF+DDVNMP    +G
Sbjct: 2609 PECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWG 2668

Query: 2056 AQPPIELLRQWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIIT 2114
             Q   E++RQ ++   +Y+L K      +VDIQ + AM  PGGGRN +  R  R F+I  
Sbjct: 2669 DQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFN 2728

Query: 2115 INEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKS 2174
                S+ S+  IF  I   H      F +E  D  T++V  T  L++     +LPTPAK 
Sbjct: 2729 CTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKF 2788

Query: 2175 HYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQ 2234
            HY+FNLRD SRV QG+  +  E  +    + +LW HE  RV  DR   ++D +W    + 
Sbjct: 2789 HYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALV 2848

Query: 2235 EILRNYMYEDFHELFQR------LDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIAD 2288
             ++     E+   L         +DF  D    A +       D   PK     Y  I  
Sbjct: 2849 SLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEE--ADAETPKI----YEPIES 2902

Query: 2289 VDNLRMIVEIHLEEYN-NISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGR 2347
              +L+  + + L+ YN +I    M++V F  A+ H+ +ISR+++ P+ +ALLVGVGGSG+
Sbjct: 2903 FSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGK 2962

Query: 2348 QSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEES 2407
            QS+TRLA+ +A Y  FQ+ +++ Y+T+   EDLKV+ R   +      F+FTD +IK+ES
Sbjct: 2963 QSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDES 3022

Query: 2408 FLEDVSNLLNAGEIPNLFALDEKQEI-CDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCR 2466
            FLE ++N+L++GE+ NLFA DE  EI  D    + ++  +   T+ +   L + F+   R
Sbjct: 3023 FLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNEN---LHDYFMSRVR 3079

Query: 2467 SQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLE--EIEMSE 2524
              LH+VL  SP+G+ FRNR  KFPAL++ CTIDWF  WP+DAL AV+  FL   +I+ S 
Sbjct: 3080 QNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSL 3139

Query: 2525 EIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKM 2584
            EI+   +    SF     +    +F   +R  +VTP SYL  I  +K +  +K  EV  +
Sbjct: 3140 EIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTL 3199

Query: 2585 KKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIV 2644
              R   GLEKL  AS  VA +  ELEA   +L+VA+ + D    M+ KE    A+  + V
Sbjct: 3200 ANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKAD----MVLKEVTMKAQAAEKV 3255

Query: 2645 KADETIANE--QAMASKAIKDECDAD--LAGALPILESALAALDTLTAQDITVVKSMKSP 2700
            KA+     +  QA+     KD+  A+  L  A P LE A AAL T+   DI  V+++  P
Sbjct: 3256 KAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRP 3315

Query: 2701 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI 2760
            P  +  +M+ + +L   K   +         +   W  + +L+    FLQ+L ++ KD I
Sbjct: 3316 PHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPS-WQESLKLMTAGNFLQNLQQFPKDTI 3374

Query: 2761 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA 2820
                +  +   Y   PD+  E  +       GLC W  AM S+  + K V P K  L   
Sbjct: 3375 NEEVIEFLSP-YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQ 3433

Query: 2821 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI 2880
            E    +AM  L+K QA L + Q +L  +Q   E    +K  L    + C  K++ A  LI
Sbjct: 3434 ENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLI 3493

Query: 2881 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR 2940
             GL GEK RW+  + E       L GD+L+++  ++Y G F   +R     +W    K R
Sbjct: 3494 SGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKAR 3553

Query: 2941 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW 3000
             IP   + +L   L +A TI  WN+ GLP+D  SI NGII+  A R+PL+IDPQ+Q   W
Sbjct: 3554 KIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIW 3613

Query: 3001 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG 3060
            IKN E  N L +  L+   +   LE+ +  G P+L+E+VGEELDP L+ +L +   K G 
Sbjct: 3614 IKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGS 3673

Query: 3061 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120
            +  +++GD  ++    FR YITTKL NP Y PE S + ++++F +T +G++DQLLG V+ 
Sbjct: 3674 TFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVIL 3733

Query: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180
             E+ +LE+E+  L+     NKR++KE+ED +L  L+S++G+++EDE+ I +LS++K  A 
Sbjct: 3734 TEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAE 3793

Query: 3181 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL 3240
            E++QK E++ ETE +I++ R  YRP+A   SIL+F + ++  +  MYQ SL  F+ LF L
Sbjct: 3794 EVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDL 3853

Query: 3241 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA 3300
            S+  S KS I +KR+  + +H TY +Y    R L+E+ K LF+  LT+ + +    +   
Sbjct: 3854 SLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHE 3913

Query: 3301 EWRFLLTGGIGLDNPYA--NLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVY 3358
            E+  L+ GG  LD          W+   +W  +  L  L  F  +  +  R +  WK  +
Sbjct: 3914 EFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWF 3973

Query: 3359 DSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLA 3418
            D   P  E  P  ++   + F+R+L+IR   PD+ I   +++I++ +G  + E    DL 
Sbjct: 3974 DKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLE 4033

Query: 3419 KAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLS----SLSLGQGQGPIAMKM 3474
            K + +S+   PLI +LS G+DP  +++         G +L      +S+GQGQ   A K+
Sbjct: 4034 KTWEESDPRTPLICLLSMGSDPTDSIIAL-------GKRLKIETRYVSMGQGQEVHARKL 4086

Query: 3475 LEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQ 3534
            L++ +  G W +LQNCHL   +M  L  +   +  E  H  FR+W+T+     FP+++LQ
Sbjct: 4087 LQQTMANGGWALLQNCHLGLDFMDELMDII--IETELVHDAFRLWMTTEAHKQFPITLLQ 4144

Query: 3535 NGVKMTNEAPKGLRANIIRSY------LMDPISDPEFFGSCKKPEEFKKLLYGLCFFHAL 3588
              +K  N+ P+GLRA + R+Y      L+D  S            ++K +LY + F H+ 
Sbjct: 4145 MSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSG----------SQWKPMLYAVAFLHST 4194

Query: 3589 VQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYE---ELPYEALRYMTGECNYGGR 3645
            VQERRKFG LGWNIPYEFN+ D   +VQ +   L+  +    + +  +RYM GE  YGGR
Sbjct: 4195 VQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGR 4254

Query: 3646 VTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAP 3705
            VTDD+D+R L +    +F+ E +   D+ F     Y +P      +Y++Y ++LP   +P
Sbjct: 4255 VTDDYDKRLLNTFAKVWFS-ENMFGPDFSFYQG--YNIPKCSTVDNYLQYIQSLPAYDSP 4311

Query: 3706 EIFGMNANADITKDQSETQLLFDNILLTQSR-SAGAGAKSSDEVVNEVASDILGKLPNNF 3764
            E+FG++ NADIT      + + D IL  Q + ++G G ++ + VV  +A D+L KLP ++
Sbjct: 4312 EVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDY 4371

Query: 3765 -DIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEV 3823
               E   R       Q MN  L QE+ R  ++L  +R +   ++ AI G  +MS +L + 
Sbjct: 4372 VPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDA 4431

Query: 3824 VSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQA 3883
            +  + + +IP  W   S+ S   LG +  + + R      W   G P  FW++GFF  Q 
Sbjct: 4432 LDCMFDARIPAWWKKASWIS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQG 4490

Query: 3884 FLTGAQQNYARK---YTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIK 3940
            FLT  +Q   R    + +   +L  +       +   PP +GV+++GL+L+GA W+++  
Sbjct: 4491 FLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNM 4550

Query: 3941 KLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAM 4000
            KL ES PK+L++ +PV+ +   +   +     Y  P+YK   R  +        N++ A+
Sbjct: 4551 KLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSCPIYKKPVRTDL--------NYIAAV 4601

Query: 4001 TLPSDQPKEHWIGRGVALLCQL 4022
             L + Q  EHW+ RGVALLC +
Sbjct: 4602 DLRTAQTPEHWVLRGVALLCDV 4623


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 1909 bits (4946), Expect = 0.0
 Identities = 1151/3346 (34%), Positives = 1828/3346 (54%), Gaps = 159/3346 (4%)

Query: 726  NGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTE 785
            N +L+   +++ Q       F      Y Q K+ +  +     L++  +    +   WT+
Sbjct: 1286 NEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTK 1345

Query: 786  GPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVR---------SKVEDFKQ 836
              + +++ +Q++ ++  + +     E          ++ K+VR           V+D   
Sbjct: 1346 TQWRQIHVEQMDVELRRFAKASSITE--------IWSLNKEVRVWDAYTGLEGTVKDMTA 1397

Query: 837  HIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAAS 896
             +  I  + +P LR RHW  +   +G     ++ +T++  L + L    D    I + A 
Sbjct: 1398 SLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAV 1457

Query: 897  KEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFI 956
            KE   EK + ++   W  ++F    +  TG  +L S +++   L+ + ++ QT+  S ++
Sbjct: 1458 KELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYV 1517

Query: 957  KPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDK 1015
            + + +Q+  W+ KL +   ++  W++VQ TW +LE IF  S DI  Q+ ++ RRF  VD 
Sbjct: 1518 EYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDA 1577

Query: 1016 TWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLS 1075
             ++++M    + ++VL       + E+LK     L L  K L EYLE KR+ FPRF+F+S
Sbjct: 1578 EFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVS 1637

Query: 1076 NDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKS--SEGEVVELIEIIST 1133
            + +LL+ILS+   P +V  HL K F+ IA ++F +  D++  ++     +  E +   + 
Sbjct: 1638 SADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAE 1697

Query: 1134 AKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTK 1193
             +  G VE WL++LE+ M  ++     +A  AY +  R  W+ D+P Q  L  SQI+WT 
Sbjct: 1698 CECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTT 1757

Query: 1194 EVQTAIPMGIKALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDV 1249
            +V  A     +  E  LK  ++    Q++ ++TL+ G+L   +R  +  +  +DVHARDV
Sbjct: 1758 DVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDV 1817

Query: 1250 LSSLV--KKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITP 1305
            ++ L+  K+ +     F WLSQLR+ W++   H    + +A  +Y YEYLGNSPRLVITP
Sbjct: 1818 VAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITP 1877

Query: 1306 LTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGK 1365
            LTDRCY TL  +LHL + GAP GPAGTGKTETTKDL +A+     VFNCS+ +DY ++G 
Sbjct: 1878 LTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGN 1937

Query: 1366 FFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCA 1425
             +KGL+  GAW CFDEFNRI +EVLSVVA Q+  I   I       +F G  + L P+  
Sbjct: 1938 IYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVG 1997

Query: 1426 VFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATY 1485
            +FITMNPGYAGR+ELP+NLKALFR  AM+ PD  +I EI+L + GFV AR L+ K +  Y
Sbjct: 1998 IFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLY 2057

Query: 1486 RLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDL 1545
             LC E LS Q HYD+G+RA+KSVL  AG+LK    N  E+ +L+R++ D N+PK ++ D+
Sbjct: 2058 TLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDI 2117

Query: 1546 PLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGF 1605
            P+F G+  DLFP + +P+         ++ +   + LQ    F  K++Q+ E++ VRH  
Sbjct: 2118 PVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSV 2177

Query: 1606 MIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHE 1665
             +VG    GK+   R L     ++ +K +  +       LNPK+VT  +L+G     + E
Sbjct: 2178 FVVGNAGTGKSKILRTLNRTYVNMKQKPVWND-------LNPKAVTTDELFGFIHHATRE 2230

Query: 1666 WSDGVLAVS-FRAFASSVTPDR--------KWLIFDGPVDAVWIENMNTVLDDNKKLCLM 1716
            W DG +  S F    SS+  ++        KW++ DG +D +WIE++NTV+DDNK L L 
Sbjct: 2231 WKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLA 2290

Query: 1717 SGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSV 1776
            S E I ++P M L+FE   L  A+PATVSR G++Y+ P  LGW P + SW++        
Sbjct: 2291 SNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWID---RRRHQ 2347

Query: 1777 IQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKER 1836
             +K  +  LFD+ VP  ++ +R   K ++   +++LV++L  L++C +        +   
Sbjct: 2348 SEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLL----TPENVPSD 2403

Query: 1837 NDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTE 1896
            + +E Y   E  F+F+ IW+ G +               L++  ISD   +     S   
Sbjct: 2404 SPKEVY---EVYFVFACIWAFGGT---------------LLQDQISDYQADF----SRWW 2441

Query: 1897 QTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTI 1956
            Q   KA  V FP +GTI+DY +V     K  PW  K+ +    P DV    ++V T +T 
Sbjct: 2442 QKEMKA--VKFPSQGTIFDY-YVDHKTKKLLPWADKIAQFTMDP-DVPLQTVLVHTTETA 2497

Query: 1957 RYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQ 2016
            R    MELL    KP + VG  G GK+V++ + L +    E Y    + F+  TT+   Q
Sbjct: 2498 RLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASL--SEDYIVSRVPFNYYTTSTALQ 2555

Query: 2017 NIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLK 2076
             I+   L+K+    +GP   K+++ F+DD+NMP  ++YG   P  L+RQ +D+ +WYD +
Sbjct: 2556 KILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQ 2615

Query: 2077 DCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLE 2136
               + ++ + Q +  M P  G    + PR  RHF +   N  S  ++ TI+ +I ++H +
Sbjct: 2616 KVMLKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQ 2674

Query: 2137 ICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPE 2196
                F    L     ++  T+  ++  M N LPT  K HY+FNLRD S V QG+  + PE
Sbjct: 2675 -QQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPE 2733

Query: 2197 TTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDN 2256
              +    +  LW+HE  RVY D+L+D  D         ++ +  M E  ++ F+ +  D+
Sbjct: 2734 CLKGPLDLIHLWLHESARVYGDKLIDKKD--------CDLFQRRMLETAYKYFEGI--DS 2783

Query: 2257 DGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLF 2316
              +++    + L++C F D + +D +Y  + D + L+ I+   L+ YN ++   M+LVLF
Sbjct: 2784 HMLLQ----QPLIYCHFAD-RGKDPHYMPVKDWEVLKTILTETLDNYNELN-AAMHLVLF 2837

Query: 2317 RFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEW 2376
              A++H+ RISRIL+ P+  ALLVGVGGSG+QS++RLAA++    VFQ+ +++GY   E 
Sbjct: 2838 EDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQEL 2897

Query: 2377 HEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDK 2436
              DL  +  +     M  VFL TD Q+ +ESFL  +++LL +GEIP+LF+ ++  +I   
Sbjct: 2898 RVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISG 2957

Query: 2437 MRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCC 2496
            +             +      +  F+   R QL ++L  SP+G   R R RKFPA+VNC 
Sbjct: 2958 IHNEVHALGMVDSREN----CWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCT 3013

Query: 2497 TIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKS-FHTSTIDLSKSFFVELQRY 2555
             IDWF +WP++AL +V+ RF+EE +  E +    I +  +  HT+  ++S  ++   +R+
Sbjct: 3014 AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRH 3073

Query: 2556 NYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQ 2615
            NY TP S+LE IS FK LL+KK++EV + K+R   G++KL + +SQV  ++  L +   +
Sbjct: 3074 NYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAE 3133

Query: 2616 LKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPI 2675
            L++ + + + ++  I  ++ +V++ + I  A+E             + EC+ADL  A P 
Sbjct: 3134 LQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPA 3193

Query: 2676 LESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDF 2735
            L +A AAL+TL   +++ +K+  +PP  V  V  A+ +L          P G   K +  
Sbjct: 3194 LVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLA--------PRGRVPK-DRS 3244

Query: 2736 WGPAKRLLGDM-RFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLC 2794
            W  AK  +G +  FLQ+L  YDK++IP   + ++ ++Y+ +P+F P  IR  S AA GLC
Sbjct: 3245 WKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLC 3304

Query: 2795 KWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLEL 2854
             WVI +  + +V   V PK+  LA A  EL  A + L   +  L ++   L+RL  + E 
Sbjct: 3305 AWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEK 3364

Query: 2855 NKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGV 2914
               +K   + +V+  +K ++ A +L+  L  +K RW  +          L GD+L+++  
Sbjct: 3365 ATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAF 3424

Query: 2915 VAYLGAFTSTYRQNQTK-EWTTLCKGR-DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDS 2972
            V+Y+G FT  YRQ     +W    + +  IP ++   L+  L +  TI  WN  GLPSD 
Sbjct: 3425 VSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDR 3484

Query: 2973 FSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGT 3032
             S +N  I+ +  RWPL+IDPQ Q  KWIKN +    L V  L +  ++  +E  + FG 
Sbjct: 3485 MSTENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETALAFGD 3543

Query: 3033 PVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLP 3092
             +L+EN+ E +DP+L+PLL + T K+G    IR+GD   E+  +FR  + TKL NPHY P
Sbjct: 3544 VILIENLEETIDPVLDPLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHTKLANPHYKP 3601

Query: 3093 ETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKIL 3152
            E   + TLLNF +T +G++ QLL  VV+ ERPDLE+ K  L     + K +LK +ED +L
Sbjct: 3602 ELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLL 3661

Query: 3153 EVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSI 3212
              LS++EG+ L+D   ++ L ++K    EI  K   A+E E+KI+  R  YRP+A  +S+
Sbjct: 3662 LRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASL 3721

Query: 3213 LFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCR 3272
            L+F + DL  I P+YQ+SL  F  LF  +IE ++K E +  R+ IL +  T+++++   +
Sbjct: 3722 LYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQ 3781

Query: 3273 SLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEIC 3332
            +LFEKDKL F   +   +LL ++ I+  E  FLL     +++ + +   +L  +SW  I 
Sbjct: 3782 ALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLR--FTVEHTHLSPVDFLTSQSWSAIK 3839

Query: 3333 RLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDK 3392
             +  +  F+ I R+       W+K  +S  P  E  P+EW+ K +  Q+++++R +RPD+
Sbjct: 3840 AIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWK-KKSLIQKLILLRAMRPDR 3898

Query: 3393 VIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAAL------LK 3446
            +   L+ F+  +LG  ++E    DL KAF +S+   P+ F+LSPG D +  L      L 
Sbjct: 3899 MTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLG 3958

Query: 3447 FADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEE 3506
            F  D G    K  ++SLGQGQ  +A   LEKA K G WV+LQN HL   W+ TLEK+ E 
Sbjct: 3959 FTIDSG----KFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLER 4014

Query: 3507 LSPESTHPDFRMWLT--SYPSPN---FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPIS 3561
             S + +H D+R++++  S P+P+    P  +L+N +K+TNE P G+ AN+  +       
Sbjct: 4015 FS-QGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYN---F 4070

Query: 3562 DPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMF 3621
            D +    C K +EFK +L+ LC+FHA V  R +FGP GW+  Y FN  DL I    L+ +
Sbjct: 4071 DQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNY 4130

Query: 3622 LNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIY 3681
            L    ++P+E LRY+ GE  YGG +TDDWDR+  R  L +F NP L E  D    + G +
Sbjct: 4131 LEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTE--DELMLAPG-F 4187

Query: 3682 FVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAG 3741
              PP  D+  Y +Y + +    +P ++G++ NA+I      +  LF  +L  Q R+A +G
Sbjct: 4188 AAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSG 4247

Query: 3742 ---AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKT 3798
                +S++E V  V  DIL KLP  F++   M++   +       V  QE  R N L++ 
Sbjct: 4248 DELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQK--NSNRSPYVLVCFQECERMNILIRE 4305

Query: 3799 IRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARL 3858
            IR S   +  ++KG   +S  +E    ++    +P+ W   +YPS   L  + ND L R 
Sbjct: 4306 IRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRC 4365

Query: 3859 KFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPID--LLGFDYEVMEDKEY 3915
            + L  W  ++  P V WLSGFF  Q+FLT   Q  ARK   P+D   L  D      ++Y
Sbjct: 4366 RELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDY 4425

Query: 3916 KHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVA 3975
             HPP +G ++HGLF++GA W+ +   + E+  K L   +PV++ K         + +Y  
Sbjct: 4426 GHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYEC 4485

Query: 3976 PLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQ 4021
            P+Y+T  R           +++    L S++    W+  GVALL +
Sbjct: 4486 PVYRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522


>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
          Length = 4490

 Score = 1900 bits (4923), Expect = 0.0
 Identities = 1180/3609 (32%), Positives = 1906/3609 (52%), Gaps = 150/3609 (4%)

Query: 469  VDAHKEKIKEVIMKESV------APTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKI 522
            V  HK+  K V++  S       A  E L+ + KY  L T   +  V  FLA N S  +I
Sbjct: 976  VAEHKDISKLVLLLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEI 1035

Query: 523  IDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRAL---VKRADIICGKLLAKMFRDH 579
              EI  Y    +EI       I +G  E+H E +  AL    K   ++  + L + ++  
Sbjct: 1036 RSEILHYATFEQEIDELK-PIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKK 1094

Query: 580  QEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFL 639
                    +E+ +   + +    +    ME  + I+  E    I+++  L   +   A L
Sbjct: 1095 MSYMIAFINEYLKKLSRPIRDLDDVRFAMEALSCIRDNE----IQMDMTLGPIEEAYAIL 1150

Query: 640  IEY-VNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELES 698
              + V  +  +    +++   + ++       ++ + +   +++  L    E F E++ +
Sbjct: 1151 NRFEVEVTKEESEAVDTLRYSFNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVIN 1210

Query: 699  YAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKK 758
            +A+  E           Q    + QI     D    K   +++ E+ FG   + Y    K
Sbjct: 1211 FAEAYELEGPMVPNIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHK 1270

Query: 759  IQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSP 818
             +  LN   +LY       S+   + E  +  V+ +++ A++  +     KL K   D  
Sbjct: 1271 TRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQ 1330

Query: 819  YALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS-TVSSFL 877
              L + K++    +DF +  PL++++ N  ++ RHW+ +S + G P     DS  + + +
Sbjct: 1331 AFLDLKKRI----DDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIM 1386

Query: 878  DMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVD--E 935
            +  L  + D  E I  +A KE  +E  + ++I  W        +++  G  +L   +  E
Sbjct: 1387 EAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGE 1446

Query: 936  IQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFS 995
            I  L++D ++   ++  + +  P++K ++ W  KL    +I++EWL VQ  W+YLE +F 
Sbjct: 1447 IITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFV 1506

Query: 996  SPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML-ERLKKSNELLELIL 1054
              DI  Q+P+E +RF  +DK+W  IM+   ++ +V+     D  + + L   +E LE+  
Sbjct: 1507 GGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQ 1566

Query: 1055 KGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDI 1114
            K L  YLEKKRL FPRFFF+S+  LLEIL +  D   +QPHL    + I +V F    D 
Sbjct: 1567 KSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTF-HAKDY 1625

Query: 1115 THMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTK--YERI 1172
              + +      E I + ++  A+G VE WL++L ++ ++S+H +   A +  +   ++ +
Sbjct: 1626 DRIMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLL 1685

Query: 1173 NWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGK----L 1228
             ++  +P Q  L   Q+ WT + + A+    K   + ++  N++  DI+  +  +    L
Sbjct: 1686 PFLSHFPAQVGLLGIQMLWTHDSEEAL-RNAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1744

Query: 1229 SMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLET--KMINA 1286
            S  +RV    L+ + VH RD+   LVK +I   +DFEWL Q R+Y++E+  +T   + + 
Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804

Query: 1287 GLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVA 1346
               Y  E+LG + RLVITPLTDRCY TL  AL +++GGAP GPAGTGKTETTKD+ + + 
Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864

Query: 1347 KQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINA 1406
            K  VVFNCSD +D+  LG+ FKGL   G+W CFDEFNRI+L VLSV AQQI  +      
Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924

Query: 1407 GADILMF-EGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIV 1465
                 +F +G  + L+P   +F+TMNPGYAGR ELP+NLK  FRTVAMMVPD  +I  + 
Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984

Query: 1466 LYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEE 1525
            L SCGF+    L+ K    Y+LC EQL+ Q HYD+G+R + SVL   G+ K   P ++E 
Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044

Query: 1526 ILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMT 1585
             +++R + D+NL K +  D PLF  + +DLFPG++L    Y +L  A+        L   
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104

Query: 1586 AFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVL 1645
              ++ K++Q+YE  +VRHG M +G    GKT+   +L  A  + C +   E        +
Sbjct: 2105 PPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTE-CGRPHREMR------M 2157

Query: 1646 NPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNT 1705
            NPK++T  Q++G+ D+ +++W+DG+ +  +R    +   +  +LI DGPVDA+WIEN+N+
Sbjct: 2158 NPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNS 2217

Query: 1706 VLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLS 1765
            VLDDNK L L +G+ I M+P   L+FE  ++E ASPATVSR GM+Y+    L WRP++ +
Sbjct: 2218 VLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQA 2277

Query: 1766 WVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMD 1825
            W+    A  + +     + L++++   +  +++ +        + N +   +NL++  + 
Sbjct: 2278 WLKKRTAQEAAV----FLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIP 2333

Query: 1826 DFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRT 1885
                    KE         L  +F+F L+WS+GA    + R K    LR+       +  
Sbjct: 2334 S-------KEEGGVSCVEHLHKLFVFGLMWSLGALLELESREKLEAFLRQ------HESK 2380

Query: 1886 RNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAP-PIPKDVM 1944
             +  ++  G+ QT                 Y+F     G WE W KKL+    P      
Sbjct: 2381 LDLPEIPKGSNQTM----------------YEFYVTDYGDWEHWNKKLQPYYYPTDSIPE 2424

Query: 1945 FNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLI 2004
            ++ I+VP +D IR + L++ +    K  +  G  GT K+V +  +L  + + E+     +
Sbjct: 2425 YSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSL 2483

Query: 2005 NFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLR 2064
            NFS+ T     Q  + S +DKR    +GPP G++M VF+DD+NMP    +G Q   E++R
Sbjct: 2484 NFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVR 2543

Query: 2065 QWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSM 2123
            Q ++    Y L K      +VD+Q++ AM  PGGGRN +  R  R F +      S+ S+
Sbjct: 2544 QMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASI 2603

Query: 2124 YTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDF 2183
              IF  I   + + C  F  +  ++   +V+    L++     +LPTP+K HY+FNLRD 
Sbjct: 2604 DKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDL 2663

Query: 2184 SRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYE 2243
            SR+ QG+   + E   +   +  L+ HE  RV  DR +   D  W   ++   +   +  
Sbjct: 2664 SRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGS 2723

Query: 2244 DFHELFQRLDFDNDGMVEADDLRSLMFCD--FHDPKREDTNYREIADVDNLRMIVEIHLE 2301
            D         +  D + E  +       D  F  PK     Y  +   D L   ++ +  
Sbjct: 2724 DAASCILPEPYFVDFLREMPEPTGDEPEDSVFEVPKI----YELMPSFDFLAEKLQFYQR 2779

Query: 2302 EYNNISK-KPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADY 2360
            ++N I +   ++LV F+ A+ H+ +ISRI++    +ALLVGVGGSG+QS++RLA+ +A Y
Sbjct: 2780 QFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGY 2839

Query: 2361 SVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGV-FLFTDTQIKEESFLEDVSNLLNAG 2419
             +FQ+ +++ Y+ T   +DLK  L K A  + +G+ F+FTD++IK+E+FLE ++NLL++G
Sbjct: 2840 QIFQITLTRSYNVTNLTDDLKA-LYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSG 2898

Query: 2420 EIPNLFALDEKQEICDKMRQ-LDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPI 2478
            EI NLFA DE  EI   +   + R+  +   T  +   L+  FI   R  LHVVL  SP+
Sbjct: 2899 EISNLFARDEMDEITQGLISVMKRELPRHPPTFDN---LYEYFISRSRKNLHVVLCFSPV 2955

Query: 2479 GDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEE--IEMSEEIRDGCIDMCKS 2536
            G+ FR R  KFP L++ CT+DWF  WP +AL AVAS FL +  I  S EI+   ++    
Sbjct: 2956 GEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGL 3015

Query: 2537 FHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLD 2596
            FH    +  +S+F   +R  +VTP SYL  I+ +K +  +K   + +  +R  +GL+KL 
Sbjct: 3016 FHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLM 3075

Query: 2597 SASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAM 2656
             AS  VA +  +L     +L VAS + DE++  +   +   AK +  V+  +  A +   
Sbjct: 3076 EASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVD 3135

Query: 2657 ASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKG 2716
               + K + ++ L  A P LE A AAL+T+   DI  V+ +  PP  +  +M+ + +L  
Sbjct: 3136 EIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQ 3195

Query: 2717 IKADKIP-DPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPN 2775
             K D +  DP  S  K    WG + +L+    FL SL ++ KD I    + +++  Y   
Sbjct: 3196 KKIDPVTMDPEKSCCKPS--WGESLKLMSATGFLWSLQQFPKDTINEETVELLQP-YFNM 3252

Query: 2776 PDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQ 2835
             D+  E  +       GL  W +AM  +  + + V P K  LA  EG L +A   L K Q
Sbjct: 3253 DDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQ 3312

Query: 2836 AALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTAL 2895
            A L E Q +L ++Q   +    +K DL N  D C KK++ A  LI GL GEK RW+  + 
Sbjct: 3313 ALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSK 3372

Query: 2896 ELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKE-WTTLCKGRDIPCSDDCSLMGTL 2954
            E       L GDIL+ +G ++YLG F   +R    K+ W    + R IP +++ +L+  L
Sbjct: 3373 EFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISML 3432

Query: 2955 GEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIK 3014
             +  TI  W + GLP D  SI NGII+  A R+PL+IDPQ+Q   WIK+ EK N L V  
Sbjct: 3433 VDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTS 3492

Query: 3015 LSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYA 3074
            L+   +   LE+ +  G P+L+E++ EELDP L+ +L K   K G +  +++GD   +  
Sbjct: 3493 LNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIM 3552

Query: 3075 PDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALI 3134
              F+ YITTKL NP + PE + K ++++F +T +G+++QLL  V+  E+ +LE E+  L+
Sbjct: 3553 DTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLL 3612

Query: 3135 LQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEK 3194
                 NKR++KE+ED +L  LS+++G++++DE+ I +L ++K  A E+S+K  VA ETE 
Sbjct: 3613 EDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEI 3672

Query: 3195 KIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKR 3254
            KI+  +  +RP A   SIL+F + +++ +  MYQ SL  F+ LF  S+  SEKS +  KR
Sbjct: 3673 KINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKR 3732

Query: 3255 LQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLD- 3313
            +  + ++ TY ++    R L+E  K LF   +T+ + L    +   E++ L+ GG  LD 
Sbjct: 3733 ITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDL 3792

Query: 3314 -----NPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVF 3368
                  PY     W+   +W  +  L  LP F  I  +  R + GWK  +D   P  E+ 
Sbjct: 3793 KACPPKPY----RWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEII 3848

Query: 3369 PEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCA 3428
            P+ + D  +   ++L+IR   PD+ +   +++I + L   + EP   +L K + +S+   
Sbjct: 3849 PDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRT 3908

Query: 3429 PLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQ 3488
            PLI  LS G+DP   +   A        +  ++S+GQGQ   A K+++ ++++G WV+LQ
Sbjct: 3909 PLICFLSMGSDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQ 3965

Query: 3489 NCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLR 3548
            NCHL   +M  L +    ++ E++   FR+W+T+ P   FP+++LQ  +K TNE P+G+R
Sbjct: 3966 NCHLGLEFMEELLETL--ITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVR 4023

Query: 3549 ANIIRSY------LMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNI 3602
            A + R++      L+D  + P           +K +LY + F H+ VQERRKFGPLGWNI
Sbjct: 4024 AGLKRTFAGINQDLLDISNLP----------MWKPMLYTVAFLHSTVQERRKFGPLGWNI 4073

Query: 3603 PYEFNETDLRISVQQLHMFLNQYE---ELPYEALRYMTGECNYGGRVTDDWDRRTLRSIL 3659
            PYEFN  D   SVQ +   L++ +    + +  +RYM GE  YGGRVTDD+D+R L    
Sbjct: 4074 PYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFA 4133

Query: 3660 NKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKD 3719
              +F+ ++ E S   +     Y +P       Y EY ++LP    PE+FG++ NADIT  
Sbjct: 4134 RVWFSEKMFEPSFCFYTG---YKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQ 4190

Query: 3720 QSETQLLFDNILLTQSRSAGAG-AKSSDEVVNEVASDILGKLPNNF-DIEAAMRRYPTTY 3777
             +    + + I   Q + +G G  ++ + +V  ++ D+L KLP ++   E   R     +
Sbjct: 4191 SNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGH 4250

Query: 3778 TQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWM 3837
              SMN  L QE+ R  +++  +R S  +++ AI+G  +MS +L + + ++ + +IP++W 
Sbjct: 4251 LNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWK 4310

Query: 3838 GKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYT 3897
              S+ S   LG +  + L R      W   G P VFW++GFF  Q FLT  +Q   R + 
Sbjct: 4311 RVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHK 4369

Query: 3898 -IPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTV 3954
               +D +    EV+    +E   PP +GV+I+GL++DGA+W+R+  KL ES PK+L+  +
Sbjct: 4370 GWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQL 4429

Query: 3955 PVMWLKPCKRADIPKRPS-YVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIG 4013
            PV+ +     +  PK P  YV P+YK   R  +         F+  + L +    +HWI 
Sbjct: 4430 PVLHIFAI-NSTAPKDPKLYVCPIYKKPRRTDL--------TFITVVYLRTVLSPDHWIL 4480

Query: 4014 RGVALLCQL 4022
            RGVALLC +
Sbjct: 4481 RGVALLCDI 4489


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 1308 bits (3385), Expect = 0.0
 Identities = 938/3431 (27%), Positives = 1627/3431 (47%), Gaps = 329/3431 (9%)

Query: 785  EGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVI 844
            E P+  V P ++  ++      L    K+F       A  + V+  ++ + +   L+  +
Sbjct: 1348 EQPWVSVQPRKLRQNLD----ALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIEL 1403

Query: 845  CNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKA 904
             +  L+ RHW+ +   +      S+  T+    D++L+      + +   A  E +LE+ 
Sbjct: 1404 KSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEF 1462

Query: 905  MEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMR 964
            ++++   W+  E  + +Y+     I    D++   + +HI     M+ SP+ K +E+   
Sbjct: 1463 LKQIREVWNTYELDLVNYQNKCRLI-RGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDAL 1521

Query: 965  EWEGKLLLLQEILDEWLKVQATWLYLEPIFS-SPDIMSQMPEEGRRFTAVDKTWRDIMRS 1023
             WE KL  +  + D W+ VQ  W+YLE IF+ S DI   +P E +RF ++   +  +M+ 
Sbjct: 1522 SWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKK 1581

Query: 1024 VMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEIL 1083
            V +   V+ V+ I  +   L++  +LL  I K L EYLE++R  FPRF+F+ +++LLEI+
Sbjct: 1582 VSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEII 1641

Query: 1084 SETKDPTRVQPHLKKCFEGIAKVEFTETLDIT-HMKSSEGEVVELIEIISTAKARGQVEK 1142
              +K+  ++Q H KK F G++ +   E   +   + S EGE V     +S  +   ++ +
Sbjct: 1642 GNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINE 1700

Query: 1143 WLVELERVMINSIHKVTGDATFAYTKYER---------INWVRDWPGQTVLCVSQIFWTK 1193
            WL  +E+ M  ++ K+  ++      + +         I W+  +  Q V+  +QI W++
Sbjct: 1701 WLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSE 1760

Query: 1194 EVQTAIP-MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQN----RVTLGALVVLDVHARD 1248
             V+TA+  MG       L +    ++  + ++   + M+     R  L  L+   VH RD
Sbjct: 1761 NVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRD 1820

Query: 1249 VLSSLVKKNISDDSDFEWLSQLRYYWQENH------LETKMINAGLRYGYEYLGNSPRLV 1302
            V  SL+K  I +   FEWLSQ+R+Y+          L  +M NA   YG+EYLG   +LV
Sbjct: 1821 VTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLV 1880

Query: 1303 ITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLA 1362
             TPLTDRCY T+  AL   LGG+P GPAGTGKTE+ K L   + +  +VFNC +  D+ A
Sbjct: 1881 QTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQA 1940

Query: 1363 LGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGAD----------ILM 1412
            +G+ F GL   GAW CFDEFNR++  +LS V+QQ+  IQ  +   ++             
Sbjct: 1941 MGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCE 2000

Query: 1413 FEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFV 1472
                ++K+ P  A+FITMNPGYAGRS LPDNLK LFR++AM  PD  +IA+++LYS GF 
Sbjct: 2001 LLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFR 2060

Query: 1473 TARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL----KYPNENEEI-- 1526
            TA  L+ KIV  ++LC EQLSSQ HYD+G+RA+KSVL +AGN+K     K   E EE   
Sbjct: 2061 TAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGE 2120

Query: 1527 ---------------LLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLA 1571
                           +L++S+ +  +PK ++ D+PL   + SD+FPGV+  + +   L  
Sbjct: 2121 AVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALRE 2180

Query: 1572 AIKDNCASMNL------QMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGA 1625
             +K  C  M L      ++   + EK+LQ+Y++  + HG M+VG    GK+ A+RVL  A
Sbjct: 2181 ELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKA 2240

Query: 1626 LNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPD 1685
            L  +      E  +    +++PK+++   LYG  D  + EW+DG+     R    SV  +
Sbjct: 2241 LERL------EGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGE 2294

Query: 1686 ---RKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPA 1742
               R+W++FDG VD  W+EN+N+VLDDNK L L +GE + + P + ++FE  DL+ A+ A
Sbjct: 2295 LQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLA 2354

Query: 1743 TVSRCGMIYMEPHMLGWRPLMLSWVNLL------------------------PASVSVIQ 1778
            TVSRCGM++    +L    +  +++  L                         A+  ++Q
Sbjct: 2355 TVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQ 2414

Query: 1779 KEFIMGLFDRMVPVSVEFIRK---HTKELSPTSDTNLVRSLMNLIDCFMD---------- 1825
             +       +    S   + K   H  +L    D   +R L +L                
Sbjct: 2415 IQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNA 2474

Query: 1826 ---DFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPIS 1882
               DF  +++  ER        ++   +++++WS+      D RLK    L E +     
Sbjct: 2475 NHPDFPMQIEQLER-------YIQRYLVYAILWSLSG----DSRLKMRAELGEYIR---- 2519

Query: 1883 DRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKD 1942
                              +  TVP P    I    +     G+W PW  K+ +       
Sbjct: 2520 ------------------RITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHK 2561

Query: 1943 VMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPL 2002
            V   +++VPTLDT+R+ AL+       KP +  GP G+GK++ + + L    + E+   +
Sbjct: 2562 VAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEV---V 2618

Query: 2003 LINFSAQTTAAQTQNIVMSKLDKRR--KGVFGPP--LGKRMVVFVDDVNMPAREVYGAQP 2058
             +NFS+ TT            + RR   GV   P  LGK +V+F D++N+P  + YG Q 
Sbjct: 2619 GLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQR 2678

Query: 2059 PIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPP-GGGRNPVTPRYMRHFNIITINE 2117
             I  +RQ ++H  +Y   D + +KL  IQ + A  PP   GR P++ R++RH  ++ ++ 
Sbjct: 2679 VISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDY 2738

Query: 2118 FSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYL 2177
                S+  I+    T++  +    P   L    + +   M  +    +       + HY+
Sbjct: 2739 PGPASLTQIYG---TFNRAMLRLIPS--LRTYAEPLTAAMVEFYTMSQERFTQDTQPHYI 2793

Query: 2178 FNLRDFSRVIQGVCLS-RPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEI 2236
            ++ R+ +R ++G+  + RP  T   E + R+W HE LR++ DRL+++ +R W    I  +
Sbjct: 2794 YSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTV 2853

Query: 2237 LRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIV 2296
               +        F  +D       E    R +++ ++        +  E+ D    R+  
Sbjct: 2854 ALKH--------FPNID------REKAMSRPILYSNWLSKDYIPVDQEELRDYVKARL-- 2897

Query: 2297 EIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAH 2356
            ++  EE  ++      LVLF   ++H+ RI RI +QP+ H LL+GV G+G+ +++R  A 
Sbjct: 2898 KVFYEEELDVP-----LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAW 2952

Query: 2357 MADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLL 2416
            M   SV+Q+++ + Y   ++ EDL+ +LR+      +  F+  ++ + +  FLE ++ LL
Sbjct: 2953 MNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLL 3012

Query: 2417 NAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMS 2476
              GE+P LF   E  E    M Q      K      S   L+  F       LHVV  M+
Sbjct: 3013 ANGEVPGLF---EGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMN 3069

Query: 2477 PIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMS------------- 2523
            P  +  ++R    PAL N C ++WF  W  +AL  V   F  ++++              
Sbjct: 3070 PSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVV 3129

Query: 2524 -----------EEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKL 2572
                       E I + C+ + ++ H +   L+K       R   +TP  YL+ I+ +  
Sbjct: 3130 YDKLPQPPSHREAIVNSCVFVHQTLHQANARLAK----RGGRTMAITPRHYLDFINHYAN 3185

Query: 2573 LLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEK 2632
            L  +KRSE+ + +    VGL K+     QV  ++ +L     +L+V +   ++ +  + K
Sbjct: 3186 LFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVK 3245

Query: 2633 ESVEVAK--------TEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALD 2684
            +  E  K         E++ K  E IA++Q    +        DL    P +  A  A+ 
Sbjct: 3246 DQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKE--------DLDKVEPAVIEAQNAVK 3297

Query: 2685 TLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLG 2744
            ++  Q +  V+SM +PPA VKL +E+IC+L G                   W   + ++ 
Sbjct: 3298 SIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTD--------------WKQIRSIIM 3343

Query: 2745 DMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804
               F+ ++  +  + I  A    ++KNY+ NP +  E +  AS A   + KW IA  +Y 
Sbjct: 3344 RENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYA 3403

Query: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864
             + K V P + +L   E + K       + +  +++++  +AR ++   +   +   ++ 
Sbjct: 3404 DMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKA 3463

Query: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924
             +     K+ R+  L+  L  E+ RW  T+         + GD L+S+  +AY G F   
Sbjct: 3464 DLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQ 3523

Query: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984
             RQN    W+   +  +I    D +    L  A     W  + LP+D    +N I++   
Sbjct: 3524 MRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRF 3583

Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044
             R+PL+IDP  QA ++I N  K   +      +  + + LE+ ++FG P+L+++V E  D
Sbjct: 3584 NRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYD 3642

Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104
            P+L P+L ++  + GG   I LGD  I+ +P F  +++T+     + P+   +VT +NF 
Sbjct: 3643 PVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFT 3702

Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164
            +T   +Q Q L  V+  ERPD++E++  L+    E + +L+++E  +L+ L+  +G IL+
Sbjct: 3703 VTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILD 3762

Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224
            D+T I  L + K  A E+++K E  +   ++++T    Y P++   S ++F++  L  I 
Sbjct: 3763 DDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIH 3822

Query: 3225 PMYQYSLTWFINLF-ILSIENSEKSEIL--AKRLQILKDHFTYSLYVNVCRSLFEKDKLL 3281
             +YQYSL +F++++  +  EN     +    +RL I+        +  V R +  +D + 
Sbjct: 3823 FLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHIT 3882

Query: 3282 FSFCLT---INLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLP 3338
            F+  L    +   + E   +     FL    I L          L  +  + + RL  LP
Sbjct: 3883 FAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLP 3942

Query: 3339 AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDK------ANEFQRMLIIRCLRPDK 3392
            AFK +  + ++  + +    DS  P   V P  W ++           R+L+I+  RPD+
Sbjct: 3943 AFKDLIAK-VQADEQFGIWLDSSSPEQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDR 4000

Query: 3393 VIPMLQEFIINRLGRAF--IEPPPFDLAKAFG-DSNCCAPLIFVLSPGADPMAALLKFAD 3449
            ++ M   F+   LG +F  I   P DL    G +     P++    PG D    +   A 
Sbjct: 4001 LLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAA 4060

Query: 3450 DQGYGGSKLSSLSLGQGQG-PIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELS 3508
            +Q    ++++S+++G  +G   A K +  AVK G WV+L+N HLA  W+  LEK    L 
Sbjct: 4061 EQ---NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQ 4117

Query: 3509 PESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGS 3568
            P   H  FR++LT   +P  PV++L+ G     E P G++AN++R++   P+S       
Sbjct: 4118 P---HACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVS-----RI 4169

Query: 3569 CKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQY--- 3625
            CK P E  +L + L +FHA++QER ++ PLGW+  YEF E+DLR +   +  +L+     
Sbjct: 4170 CKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKG 4229

Query: 3626 ------EELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENS---DYKFD 3676
                  +++P+ AL+ +  +  YGGRV +++D+R L + L + F     ++      K D
Sbjct: 4230 RQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVD 4289

Query: 3677 SSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANA----------DITKDQSETQLL 3726
                  +P     + ++++ + LP T  P   G+  NA          D+     + Q+L
Sbjct: 4290 GHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQML 4349

Query: 3727 FDNILL--------TQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYT 3778
             D   L        T++ S   G  +    ++  AS+ L  +P      + ++R      
Sbjct: 4350 EDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTL---SHLKRTVENIK 4406

Query: 3779 QSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMG 3838
              +     +E+    KLL+ +R    ++ +  +G    +  L  +++ ++   +P  W  
Sbjct: 4407 DPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSH 4466

Query: 3839 KSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPP--------VFWLSGFFFTQAFLTGAQQ 3890
             + P+   +  +V+DF  R+K LQ                    L G F  +A++T  +Q
Sbjct: 4467 YTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQ 4526

Query: 3891 NYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKIL 3950
              A+  +  ++ L  +  V    +          + GL L GA+ N     L+ +    +
Sbjct: 4527 YVAQANSWSLEELCLEVNV-TTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNA----I 4581

Query: 3951 YDTVPVMWLKPCKRADIPKRPSYVA-PLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKE 4009
               +P+  L+  K+ +  K+ S V  P+Y    R  ++        F +   + + +   
Sbjct: 4582 STALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLI--------FTVDFEIATKEDPR 4633

Query: 4010 HWIGRGVALLC 4020
             +  RGVA+LC
Sbjct: 4634 SFYERGVAVLC 4644


>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
          Length = 4314

 Score = 1268 bits (3282), Expect = 0.0
 Identities = 963/3475 (27%), Positives = 1667/3475 (47%), Gaps = 308/3475 (8%)

Query: 666  IFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRY------- 718
            + E H+ +IK++IE  +  +K R + + +ELE +  + ++     D+ +  ++       
Sbjct: 1021 MMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSA 1080

Query: 719  --LKKAQILNGKLDLAADKI----EQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYET 772
              +K+ +I    L++   K+      F  EE  F    S+                  E+
Sbjct: 1081 KLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKD--------------IES 1126

Query: 773  AVEFSSNYRAWTEGPYHKVNPDQV---------EADIGNYWRGLYKLEKTFHDSPYALAM 823
              +  + Y  + +G     N D +         E  + N+   L K+E+  H       M
Sbjct: 1127 CAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEE--HS-----VM 1179

Query: 824  TKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEP 883
            T K++S+V+ +K  IP+++ +    L P HW  +  ++G P   S +  +   L    + 
Sbjct: 1180 TVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADT 1239

Query: 884  YIDR---FEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLL 940
             + +    + ++  A  E ++ +A+ ++        F +  Y ++ +  +  + + + ++
Sbjct: 1240 IVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIV 1299

Query: 941  D---DHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSP 997
            +   D+    Q+++ SP+ K +E ++  WE KL  L E L     +Q  W+YLEPIF   
Sbjct: 1300 NQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGR- 1358

Query: 998  DIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGL 1057
                 +P+E  RF  VD+ +R IM  + +D  V T+ T   +   L    + L+   K L
Sbjct: 1359 ---GALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSL 1415

Query: 1058 NEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTE-TLDITH 1116
            NE+LE+KR  FPRF+F+ +D+LLEIL ++ +P+ +Q HLKK F GI  V F E +  IT 
Sbjct: 1416 NEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITA 1475

Query: 1117 MKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVR 1176
            MKS EGEVV     +  +     VE WL +L   M  ++ ++  +        +      
Sbjct: 1476 MKSLEGEVVPFKNKVPLSN---NVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPS 1532

Query: 1177 DWPGQTVLCVSQIFWTKEVQTAIP---------MGIKALEQYLKTCNRQIDDIVTLVRGK 1227
             +P Q +    QI +T++V+ AI            +  LEQY    +   +D      G 
Sbjct: 1533 LFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNI-DTSSEDPGNTESGI 1591

Query: 1228 LSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLE-TKMINA 1286
            L ++    L AL++  +H  DV+  L +  +    D+ W  QLR+Y + +H    +M+++
Sbjct: 1592 LELK----LKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCCVQMVDS 1647

Query: 1287 GLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVA 1346
              +Y YEY GN+ +LV TPLTD+CY TL  A+ + LGG P GPAGTGKTE+ K L   + 
Sbjct: 1648 EFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLG 1707

Query: 1347 KQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINA 1406
            +Q +VFNC +G+D  ++G+ F GL+ CGAW CFDEFNR++  VLS V+ QI TIQ  +  
Sbjct: 1708 RQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKN 1767

Query: 1407 GADILMFEGTELKLDPTCAVFITMNP---GYAGRSELPDNLKALFRTVAMMVPDYAMIAE 1463
               +    G E++++    +FITMNP   GY GR +LPDNLK LFR VAM  PD  +IAE
Sbjct: 1768 HRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAE 1827

Query: 1464 IVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY---- 1519
            ++LYS GF  A+ LS K+VA + L  E L+ Q HYD+G+RA+K+VL  +GNL  +     
Sbjct: 1828 VILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSG 1887

Query: 1520 --PNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNC 1577
               N NE  ++++++    + KF   D   F+ +  D+FPG++L + +Y++L AA+K   
Sbjct: 1888 TTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVF 1947

Query: 1578 ASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEE 1637
               N ++     +K L++YE +  R G +IVG    GK++ +R+L  AL   C+ G +  
Sbjct: 1948 EEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAAL---CKTGKV-- 2002

Query: 1638 NKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDA 1697
              V+   +NPK++   QL G  D  + EWSDGVL  S R           W+I DG +D 
Sbjct: 2003 --VKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDP 2060

Query: 1698 VWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHML 1757
             WIE++N+VLDDN+ L + SGE IQ  P +N +FE  DL  ASPAT+SR GMI++     
Sbjct: 2061 EWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEET 2120

Query: 1758 GWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLM 1817
                L+ SW+   PA      + +I   F++    +++++ K    +  TS   LV ++M
Sbjct: 2121 DLNSLIKSWLRNQPAEYRNNLENWIGDYFEK----ALQWVLKQNDYVVETS---LVGTVM 2173

Query: 1818 NLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNK-ILREL 1876
            N +            L    D +        F+ +LI  +G +     RL+F K +    
Sbjct: 2174 NGLS----------HLHGCRDHDE-------FIINLIRGLGGNLNMKSRLEFTKEVFHWA 2216

Query: 1877 MESPIS---------DRTRN---TFKLQSGTEQTS---SKALTVPFPEKGTIYDYQFVTE 1921
             ESP           D TR    T+ L+   + T+   S  LT+P      +     +  
Sbjct: 2217 RESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLP------VIQTPDMQR 2270

Query: 1922 GIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTG 1981
            G+  ++PW+                       DT             ++P I VGP G G
Sbjct: 2271 GLDYFKPWLSS---------------------DT-------------KQPFILVGPEGCG 2296

Query: 1982 KSVYITNFLLNQLNKEIYKPLLINFSAQTTA-------AQTQNIVMSKLDKRRKGVFGPP 2034
            K + +  +  +QL     +   ++ SAQTT+       +QT  ++ +   +    V+ P 
Sbjct: 2297 KGMLL-RYAFSQLRST--QIATVHCSAQTTSRHLLQKLSQTCMVISTNTGR----VYRPK 2349

Query: 2035 LGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGP 2094
              +R+V+++ D+N+P  + +G    +  L+Q L +  +YD ++   + L +IQI+ +M  
Sbjct: 2350 DCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD-ENLEWVGLENIQIVASMSA 2408

Query: 2095 PGG-GRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTT-QI 2152
             G  GR+ +T R+     + +I+    + + TI+   L   L    K    +   +   +
Sbjct: 2409 GGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYL 2468

Query: 2153 VNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVC---LSRPETTETTEVIKRLWV 2209
            + G+M    E ++        SHY F     ++ + G+    L    +    + +  +  
Sbjct: 2469 LAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVA 2528

Query: 2210 HEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLM 2269
            +E  R++ D+++   +    ++    IL +    D+      LD  +D        R   
Sbjct: 2529 YEARRLFRDKIVGAKE----LHLFDIILTSVFQGDWGS--DILDNMSDSFYVTWGARHNS 2582

Query: 2270 FCDFHDPKREDTNYREIADVDN--LRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRIS 2327
                   +    + + +  +++  L+ +++  L  Y   ++  ++++LF   +E++SRI 
Sbjct: 2583 GARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQN-LDILLFHEVLEYMSRID 2641

Query: 2328 RILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKC 2387
            R+L  P    LL G  G GR+++T L +HM    +F  +IS+GY+  ++  DLK +L+  
Sbjct: 2642 RVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLA 2701

Query: 2388 AEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKT 2447
                 Q V L  D Q    +FLE +++LL++GE+P L+ L+E + +   ++      D+ 
Sbjct: 2702 GIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLK------DQA 2755

Query: 2448 KQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPED 2507
             Q DG    +FN F    +  LH+VL M      F       PAL   C + W + W   
Sbjct: 2756 SQ-DGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNS 2814

Query: 2508 ALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFV--ELQRYNYVTPTSYLE 2565
            +++ +      E    E+  D      K  ++   D  KSF +  E  +    TP+ Y+ 
Sbjct: 2815 SMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMT 2874

Query: 2566 LISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDE 2625
             +  +  +   K+ E++K +   + G+ KL+ A + V  +  +       LK    E D 
Sbjct: 2875 FLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADA 2934

Query: 2626 --MMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAAL 2683
               MI +  +     KTE + +    IA E+ +  +  K++ D +L    P++  A  A+
Sbjct: 2935 ALQMITVSMQDASEQKTE-LERLKHRIA-EEVVKIEERKNKIDDELKEVQPLVNEAKLAV 2992

Query: 2684 DTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLL 2743
              +  + ++ ++S++ PP  ++ ++E +  L GI               +  W   K  L
Sbjct: 2993 GNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGI--------------FDTSWVSMKSFL 3038

Query: 2744 GDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNP-DFVPEKIRNASTAAEGLCKWVIAMDS 2802
                  + +  +D  NI       + +    N   F P+  + ASTAA  L  WV A   
Sbjct: 3039 AKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQ 3098

Query: 2803 YDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADL 2862
            Y  V + + P + + A  E  LK   D  RK +  L  V  K++ L++  +    + A L
Sbjct: 3099 YSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKL 3158

Query: 2863 ENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFT 2922
            E +V    + ++ AE LI  L  E  RW+   +E+ +    L     +++  + YL A  
Sbjct: 3159 EAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAP 3218

Query: 2923 STYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIM 2982
             + R+   +EWT   K   +   D    + T  E +    W   GLPSD  SI+N ++I+
Sbjct: 3219 ESLRKTCLEEWT---KSAGLEKFDLRRFLCTESEQLI---WKSEGLPSDDLSIENALVIL 3272

Query: 2983 N-------ARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVL 3035
                    +R  P +IDP SQA +W+K   K + L VI   + +++  LE  ++FG  ++
Sbjct: 3273 QIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLI 3332

Query: 3036 LENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETS 3095
            ++ + + ++P+L PLL +    QG    +++GD  I+Y  +FR +++T+  NP   P+ +
Sbjct: 3333 IQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAA 3391

Query: 3096 VKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVL 3155
              VT +NF  T  G++ QLL + +  E+PDLEE+K  L+ Q  + K QL ++E+ +LE L
Sbjct: 3392 SIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETL 3451

Query: 3156 SSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFF 3215
            ++S+GNILE++  I+ L+ +KA +  I +  + + + +  +D  R  Y P+A  +S ++F
Sbjct: 3452 ATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYF 3511

Query: 3216 SLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLF 3275
             ++DL+ I  MY++SL  F+ LF  +++N + SE   +R+Q L     + +Y  +CR LF
Sbjct: 3512 IISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLF 3571

Query: 3276 EKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIG-----LDNPYA---NLCTWLPQ-K 3326
            + D+L+F+        +H     + EW       +G      D+       L +W+ Q +
Sbjct: 3572 KADQLMFALHFVRG--MHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQER 3629

Query: 3327 SWDEICRLDDLPA-FKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLII 3385
            SW        LP+ ++T+  E   L   W+  Y++     E FP     K + FQ++L++
Sbjct: 3630 SWAVATLKIALPSLYQTLCFEDAAL---WRTYYNNSMCEQE-FPSILAKKVSLFQQILVV 3685

Query: 3386 RCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALL 3445
            + LRPD++   +  F    LG   + P P +L + + ++    P++ ++SPGADP   L 
Sbjct: 3686 QALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQ 3745

Query: 3446 KFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCE 3505
            + A+ +   G     +++GQGQ  +A++ML++  + G W+ L+N HL  SW+P LEK   
Sbjct: 3746 ELANAE-RSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELN 3804

Query: 3506 ELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEF 3565
             L P+ T   FR+WLT+   PNF   +LQ+ +K+T E+P GL+ N++R+Y       PE 
Sbjct: 3805 TLQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTY---ESWTPEQ 3858

Query: 3566 FGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQY 3625
              S K        L+ L +FHA  QERR + P GW   YEF+ +DLR     +    +  
Sbjct: 3859 I-SKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA 3917

Query: 3626 EELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYF--- 3682
            +++ +E +  +     YGGR+ + +D R L+S L +FFN  +++  + +   S   +   
Sbjct: 3918 KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVS 3977

Query: 3683 VPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGA 3742
            +P S     Y    + +P    P  FG+ AN   +  +  +  +   + +   RS  AG+
Sbjct: 3978 LPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRIL-GRSITAGS 4036

Query: 3743 KSSDEVVNEVASDILG---KLPNNFDIEAAMRRYPTTYTQSMNTVL---VQEMGRFNKLL 3796
            K   E+ +   S +L    KL  N ++    ++ P    +  + +L   + E     +L+
Sbjct: 4037 KFDREIWSNELSPVLNLWKKLNQNSNL--IHQKVPPPNDRQGSPILSFIILEQFNAIRLV 4094

Query: 3797 KTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLA 3856
            +++  S   + K I+G  ++S++++++ S++LN K P  W  K      PL  Y+   +A
Sbjct: 4095 QSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPL-QYLRGLVA 4153

Query: 3857 RLKFLQQWYEVGPPPVFW-----LSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVME 3911
            R   +Q W +             LS  F    FL   +Q  AR     +D L F   V  
Sbjct: 4154 RALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF---VAS 4210

Query: 3912 DKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPK-- 3969
             K      +  + I GL L+G S++    +L+E+      D+  V  + PC    IP+  
Sbjct: 4211 WKGRLQEAKLQIKISGLLLEGCSFDG--NQLSENQ----LDSPSVSSVLPCFMGWIPQDA 4264

Query: 3970 ------RPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVAL 4018
                        P+Y ++ER  V++           + +P    ++ WI  G AL
Sbjct: 4265 CGPYSPDECISLPVYTSAERDRVVTN----------IDVPCGGNQDQWIQCGAAL 4309


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
            sapiens]
          Length = 4515

 Score =  937 bits (2421), Expect = 0.0
 Identities = 594/1892 (31%), Positives = 955/1892 (50%), Gaps = 227/1892 (11%)

Query: 2328 RILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKC 2387
            R+L +   +   +G+ G G+++   LA ++ D  +++V IS      E+ E  K +    
Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712

Query: 2388 AEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKT 2447
                   V +  +  I+++SFLED++ ++++G IP+LF   E   I  K+R L  Q    
Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772

Query: 2448 KQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPED 2507
                    +L + F       LH+ + MSP G +FR   R +P++++ CTIDW++ WPE+
Sbjct: 2773 DNRQ----SLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEE 2828

Query: 2508 ALQAVASRFLEE---IEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYL 2564
            AL  VA+ FL+E    E  E +++     C   H S  DL++ +F E  R+ Y TP SYL
Sbjct: 2829 ALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYL 2888

Query: 2565 ELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVD 2624
            + + TF  +L  +  E+   + R+ +GL  +  A++ V  MQ EL  L PQ++  +KE +
Sbjct: 2889 QFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETE 2948

Query: 2625 EMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALD 2684
             +M  + K+S  V K + +VK DE I  E+    +    +   +L   LP  + A+ AL+
Sbjct: 2949 TLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALN 3008

Query: 2685 TLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLG 2744
             L   D+  ++    PP  V  VM A+CIL   K +               W  AK LL 
Sbjct: 3009 ALDKADVAELRVYTRPPFLVLTVMNAVCILLQKKPN---------------WATAKLLLS 3053

Query: 2745 DMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804
            +  FL+ L   DKD+IP      ++K  +  PDF P KI   S A   LC+WVIA+++Y 
Sbjct: 3054 ETGFLKKLINLDKDSIPDKVFVKLKK-IVTLPDFNPHKISLVSVACCSLCQWVIALNNYH 3112

Query: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864
            +V K+V PK+I++A A+  LKIA   L +KQ  L+ V++ L  LQ   +    +K  L N
Sbjct: 3113 EVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLAN 3172

Query: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924
            +  + S++ + A  L+  L  EKTRW  T  ++      + GDIL+S+  + Y G  T  
Sbjct: 3173 RKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPE 3232

Query: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984
            +RQ    +W T C    I  S   SL+  + +   I  W+  GLP   +S++N I+I N 
Sbjct: 3233 FRQLIVNKWETFCIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNG 3292

Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044
            ++WPL+IDP  QA+KWI+ ME  + L  + + + +Y + +EN ++ G  VLL+N+ E L 
Sbjct: 3293 QQWPLLIDPHRQAHKWIRQME-GSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLA 3351

Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104
            P L+ +L K  +++ G   IR+GD+  EY  +FR Y++T++ NPH+LP     VT++NF 
Sbjct: 3352 PGLKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFT 3411

Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164
            +T +G+QDQLL  VV  E P LE+++  L+   + +   L+E+E+K L +L  + G+IL+
Sbjct: 3412 VTFQGLQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILD 3471

Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224
            D+  +  L  SK  +NEIS++ E  ++ E +I   R  Y PIA   ++L+F +ADL  I 
Sbjct: 3472 DDKIVDTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQIN 3531

Query: 3225 PMYQYSLTWFINLFILSIENSEKSE-------------------------------ILAK 3253
             MYQ+SL WF  +F+ S+ +  K +                               +L K
Sbjct: 3532 YMYQFSLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDK 3591

Query: 3254 RLQILKDHFTYSLYVNVCRSLFEKDKLLFSF--CLTI-------NLLLHERA-INKAEWR 3303
             ++   D  T S++  V  +LF +DKL FSF  C  I       NL+  +   + + EW 
Sbjct: 3592 HIKSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWN 3651

Query: 3304 FLLTGGIGLDNPYA---------------NLCTWLPQKSWDE-------------ICR-- 3333
              L  GI ++   A                   WL    W +             +C+  
Sbjct: 3652 IFLYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSL 3711

Query: 3334 ---LDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWE----------------D 3374
               +     FK  +  +  +   +     SLE + +  PEE E                +
Sbjct: 3712 LSNVSQWDTFKNSKAVYSLISTPFSSENASLEENTKP-PEETELLNENKETCNPINFPWE 3770

Query: 3375 KANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVL 3434
            K   FQR+++++ LRP+ +   +++FI  ++G  +++    +L  A+  SN   PLI + 
Sbjct: 3771 KLTSFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQ 3830

Query: 3435 SPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAV-KEGTWVVLQNCHLA 3493
            + G D    LL+FA +       ++ +SLG+ Q   A  ++ KA+ K   WV LQNCHLA
Sbjct: 3831 THGIDLTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLA 3890

Query: 3494 TSWMPTLEKVCEEL-SPEST-HPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANI 3551
            TS+MP L  + E   SP  T  P+FR+WL+S    +FP+ VL+ G+K+  E+P+GL++N+
Sbjct: 3891 TSFMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNL 3950

Query: 3552 IRSYLMDPISD--PEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNET 3609
            ++++      +   E F +    + +KKLL+ LCFF+A++ ER+ +G LGWNI Y+FN +
Sbjct: 3951 LQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSS 4010

Query: 3610 DLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVE 3669
            DL ++++ L   L     + ++ALRY+ GE  YGGRV D+WD+R L+++L KF NPE+++
Sbjct: 4011 DLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVLK 4070

Query: 3670 NSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDN 3729
            + D+ F          S   K YI   ++LP    PE+ G++  A  +  +++ +   +N
Sbjct: 4071 D-DFSFSR--------SASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIEN 4121

Query: 3730 ILLTQSRSAGAG-----AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMN-- 3782
            ++  Q ++  A       +S DE+V E+ SD+L +LP   + E      P+T    M+  
Sbjct: 4122 LIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMMSSS 4181

Query: 3783 ---------------------TVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLE 3821
                                 T L QE+ RF+KLL  I  S  ++Q AIKG  +++ +LE
Sbjct: 4182 IWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELE 4241

Query: 3822 EVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEV-------------- 3867
            E+ +S LN+++P +W   +Y S KPL S+++D + RL F   W +V              
Sbjct: 4242 EIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVT 4301

Query: 3868 -------------------------GPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDL 3902
                                     G P  +WL  FFF QAFL    Q+Y R   I +D 
Sbjct: 4302 VWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDA 4361

Query: 3903 LGFDYEVME---DKEYKH-------------------PPEDGVFIHGLFLDGASWNRKIK 3940
            L F + V+    DK+ K                        GV+I GLF++GA WNR+ K
Sbjct: 4362 LTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQK 4421

Query: 3941 KLAESHPKILYDTVPVMWLKPCKRADIPKRPS---------YVAPLYKTSERRGVLSTTG 3991
             L +S P  +    P ++  P K +      S         +  P+Y+T ER  +L+TTG
Sbjct: 4422 ILEDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFECPVYQTPERSRILATTG 4481

Query: 3992 HSTNFVIAMTLPSDQPKEHWIGRGVALLCQLN 4023
              TNF+ ++ L + +P  HWI   VALLC+ N
Sbjct: 4482 LPTNFLTSVYLSTKKPPSHWITMRVALLCEKN 4513



 Score =  719 bits (1857), Expect = 0.0
 Identities = 440/1227 (35%), Positives = 647/1227 (52%), Gaps = 139/1227 (11%)

Query: 759  IQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSP 818
            I+  L    +L+E   E+      W       ++ + V+ ++      +  LEK    S 
Sbjct: 992  IEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGLPKSD 1051

Query: 819  YALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLD 878
                M   ++  V +FKQ +P+I  + NP L+PRHWEA+  I+G  +    +  V + L 
Sbjct: 1052 ----MVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLDKNCKVENLLA 1107

Query: 879  MNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDA--VEFVIHSYRETGTFILASVDEI 936
            + +  Y +    +S +A+ E +LEK + K+I  W+   +  ++H       FI+ S+D+I
Sbjct: 1108 LKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSIFIIPSIDDI 1167

Query: 937  QMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSS 996
               L++  +   T++GSP I P +  + EW+  L L    L+EW+  Q  WLYLEP+F S
Sbjct: 1168 SAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHS 1227

Query: 997  PDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKG 1056
             +I  Q+P E   F+ V   W+ IM  +   ++ L + T   +LE L+  N  LE I K 
Sbjct: 1228 SEIRRQLPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKS 1287

Query: 1057 LNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET----L 1112
            L +YLE KRL FPRF+FLSN ELL+IL+++++P  VQPHL KCFE I ++   +      
Sbjct: 1288 LEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPP 1347

Query: 1113 DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERI 1172
             +  + S+EGE + L + I   + R  VE+WLV +E+ M + + K             +I
Sbjct: 1348 AVKMLISAEGEGLVLPKKI---RVRSAVEQWLVNVEKSMFDVLKKERYIYNIILLFQSQI 1404

Query: 1173 NWVRDWPGQTVLCVSQIF--WTKEVQTAIPMGIKALEQYLKTCN-RQIDDIVTLVRGKLS 1229
             +  D       CV      +++E    +  G+         C+  ++ D+V L     +
Sbjct: 1405 MFYND-------CVKSFVSSYSREKLEKVHAGLM--------CHLEEVADLVVLDTS--N 1447

Query: 1230 MQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENH--LETKMINAG 1287
             + +  LGAL++L VH RD++ +L+ KNI +  DFEW   L+Y W E          NA 
Sbjct: 1448 SRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNAS 1507

Query: 1288 LRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAK 1347
              YGYEYLG + RLVITPLTDRC+ TL  ALHL+LGG P GPAGTGKTET KDLAK++ K
Sbjct: 1508 FTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGK 1567

Query: 1348 QCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAG 1407
             CVVFNC + LDY  + KFF GL+  GAW+CFDEFN IDLEVLSV+A QILTI+   +  
Sbjct: 1568 HCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNY 1627

Query: 1408 ADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLY 1467
            +   + EG E++++ +CAVFITMNP Y G  ELPDNLK+LFR VAMMVP Y MIAEI+L+
Sbjct: 1628 SARFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILF 1687

Query: 1468 SCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY---PNENE 1524
            S GF +A  LS K+   Y L  +QLS Q HY++G+R++K VL  AG  K ++      +E
Sbjct: 1688 SFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSEADE 1747

Query: 1525 EILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQM 1584
             ++++ +I + +LPK    D+PLFE I  D+FP V + K +   L   I      + LQ 
Sbjct: 1748 TLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQN 1807

Query: 1585 TAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDI-------------CE 1631
             +   EKI+Q Y  + V  G M+VG   GGKT+  R+L  AL  +               
Sbjct: 1808 WSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSAS 1867

Query: 1632 KGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTP------- 1684
            K    + KV I VLNPK VT+ +LYGQ D  + EW+DG+L+ + R++    TP       
Sbjct: 1868 KISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDI 1927

Query: 1685 ---------------------------------------------DRKWLIFDGPVDAVW 1699
                                                         D +W+I DGPVD  W
Sbjct: 1928 DLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFW 1987

Query: 1700 IENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGW 1759
            +EN+N+VLDD + LCL + E I ++ ++ +IFE  +L  ASPATVSRC M+YM+P  LGW
Sbjct: 1988 VENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGW 2047

Query: 1760 RPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTK-ELSPTSDTNLVRSLMN 1818
             P + SW+      +S    + +  +    V   ++FIR   K +  P  D  +V +L  
Sbjct: 2048 EPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCR 2107

Query: 1819 LIDCFMD-----------DFADEVKLKERN--------------DRETY----------S 1843
            ++D F D           D  ++   KE N              D  T+           
Sbjct: 2108 ILDAFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVTFKDIEKRDENTWYPEKNPDKLTK 2167

Query: 1844 LLEGIFLFSLIWSVGASCTDDDRLKFN 1870
            +++ +F+F+  W+ G +   +D  + N
Sbjct: 2168 IIQKLFVFAFTWAFGGALNREDEHREN 2194



 Score =  167 bits (424), Expect = 1e-40
 Identities = 99/297 (33%), Positives = 160/297 (53%), Gaps = 15/297 (5%)

Query: 1954 DTIRYSALMELLTTHQKPSIFVGPT---GTGKSVYITNFLLNQLNKEIYKP--------L 2002
            DT+ YS + +  +  Q  +I +  T    TG S   T     + NK++ K          
Sbjct: 2369 DTLLYSEIKKSSSLKQNITILIPETHKTATGSSDNPTKKPEVRTNKKLLKNNDHKGVVVS 2428

Query: 2003 LINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIEL 2062
             INFS   TAA+T+ +++ KL +R K   G P   R+++F+DD+NMP  ++YGAQPP+EL
Sbjct: 2429 TINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPPLEL 2488

Query: 2063 LRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKS 2122
            +RQ LD    YD +  +   + D+ I+ A  P     N ++PR ++HF+++ +   S   
Sbjct: 2489 IRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPV---VNDISPRLLKHFSMLVLPHPSQDI 2545

Query: 2123 MYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRD 2182
            + TIF   L  +  I   F  E      QI++ ++ +Y +  +N+LPTP K HY+FNLRD
Sbjct: 2546 LCTIFQAHLGIYFSI-NNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLRD 2604

Query: 2183 FSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRN 2239
              +++ G+  +      + E+   L+VHE  RV++DRL+D TD+S     +   L N
Sbjct: 2605 MFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELEN 2661


>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
          Length = 798

 Score =  478 bits (1230), Expect = e-134
 Identities = 284/824 (34%), Positives = 446/824 (54%), Gaps = 48/824 (5%)

Query: 3219 DLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKD 3278
            DL+ I PMYQ+SL  F  +F  ++E +   E L +R+  L D  T+S+Y    R LFE D
Sbjct: 3    DLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECD 62

Query: 3279 KLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLP 3338
            KL +   LT  +LL  R +N  E  FLL   +      A+   +L  ++W  +  L  + 
Sbjct: 63   KLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGT--ASPVEFLSHQAWGAVKVLSSME 120

Query: 3339 AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQ 3398
             F  + R+       WKK  +S  P  E  P+EW++K    QR+ ++R +RPD++   L+
Sbjct: 121  EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKT-ALQRLCMLRAMRPDRMTYALR 179

Query: 3399 EFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQG------ 3452
            +F+  +LG  ++     D A +F +S    P+ F+LSPG DP    LK  + QG      
Sbjct: 180  DFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDP----LKDVESQGRKLGYT 235

Query: 3453 YGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPEST 3512
            +      ++SLGQGQ  +A   L+ A K+G WV+LQN HL   W+ TLEK  EE S E++
Sbjct: 236  FNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENS 294

Query: 3513 HPDFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFG 3567
            HP+FR+++++ P+P+      P  +L+N +K+TNE P G+ AN+ ++  +D  +  +   
Sbjct: 295  HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA--LDNFTQ-DTLE 351

Query: 3568 SCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEE 3627
             C +  EFK +L+ LC+FHA+V ERRKFGP GWN  Y FN  DL ISV  L+ FL    +
Sbjct: 352  MCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAK 411

Query: 3628 LPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSG 3687
            +PY+ LRY+ GE  YGG +TDDWDRR  R+ L +F  PE++E    +   +  + +P + 
Sbjct: 412  VPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEG---ELSLAPGFPLPGNM 468

Query: 3688 DHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSA----GAGAK 3743
            D+  Y +Y        +P ++G++ NA+I      ++ LF  +L  Q R +    GAGA 
Sbjct: 469  DYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGA- 527

Query: 3744 SSDEVVNEVASDILGKLPNNFDIEAAMRRYP--TTYTQSMNTVLVQEMGRFNKLLKTIRD 3801
            + +E V  +  +IL ++ + F+I   M +    T Y      V  QE GR N L + I+ 
Sbjct: 528  TREEKVKALLEEILERVTDEFNIPELMAKVEERTPYI----VVAFQECGRMNILTREIQR 583

Query: 3802 SCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFL 3861
            S   ++  +KG   M++ +E + +++    +PE W  ++YPS   L ++  D L R+K L
Sbjct: 584  SLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKEL 643

Query: 3862 QQWY-EVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHP 3918
            + W  +   P   WL+GFF  Q+FLT   Q+ ARK   P+D +    ++ +   +E++ P
Sbjct: 644  EAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSP 703

Query: 3919 PEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLY 3978
            P +G +IHGLF++GA W+ +   + E+  K L   +PVM++K         R  Y  P+Y
Sbjct: 704  PREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVY 763

Query: 3979 KTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022
            KTS+R            +V    L + +    W+  GVALL Q+
Sbjct: 764  KTSQR---------GPTYVWTFNLKTKENPSKWVLAGVALLLQI 798


>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
          Length = 4753

 Score =  225 bits (574), Expect = 6e-58
 Identities = 337/1643 (20%), Positives = 631/1643 (38%), Gaps = 304/1643 (18%)

Query: 833  DFKQHIPLIQVICNPGLRPRHWEAMSAIVGY-PLQPSDDSTVSSFLDMNLEPYIDRFEGI 891
            +F+ ++PL+  + +   +  + + +   +G   LQ  +  T+   L   L  + DR   +
Sbjct: 1082 EFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQV 1141

Query: 892  SEAASKEYSLEKAMEKMITEWDA-----VEFVIHSY-----------------------R 923
             +  ++    ++ + ++   W+A     + F++H                         +
Sbjct: 1142 WQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDK 1201

Query: 924  ETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKV 983
            ++GTFIL+    +Q  + + +     +          K   EW   +  L  +L+ WL  
Sbjct: 1202 DSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTF 1261

Query: 984  QATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTID------ 1037
            Q  W++L  +     I     +   RF  +D  +R +MR  + D  VL++V         
Sbjct: 1262 QQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPY 1321

Query: 1038 ---RMLERLKKSNEL-LELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQ 1093
               + L++L ++  + LE I+  L   L      FPR FFLS+ EL+ +L+   +    Q
Sbjct: 1322 FQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQ 1381

Query: 1094 PHLKKCFEGIAKVEF----TETLDITHMKSSEGEVVELIEIISTAKARGQ---------- 1139
              +++CF  +  V F    T   +    +SS     + +E ++   A G+          
Sbjct: 1382 LWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQ-VEALAVLGAGGEEVKLQGPLPL 1440

Query: 1140 ---VEKWLVELERVM-INSIHKVTG-------------DATFAYTKYERI-------NW- 1174
               + KWL  LE+ + +  +H + G             +A     K  ++       +W 
Sbjct: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI 1500

Query: 1175 --VRDWPGQTVLCVSQIFWTKEVQTAI-PMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQ 1231
              V+ +P Q VL   ++ W  E++ A+   G  A+   +    R+++ +V  +R + + Q
Sbjct: 1501 DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAM---VSMHMRKLEVLVNFMRAQRASQ 1557

Query: 1232 NRVTL---------GALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETK 1282
               +L          AL+V+ V  RD+   L +  +SD +DF W+ QL+Y+    H+  K
Sbjct: 1558 GGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPK 1617

Query: 1283 ------------------------MINAGLRYGYEYLGNSPRLVITP--LTDRCYRTLFG 1316
                                    ++     Y YEYLG  PRL   P  L +R    L  
Sbjct: 1618 SPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLL 1675

Query: 1317 ALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAW 1376
            AL     G   GP G GK      LA+A+ +Q V+  CS  ++   L  +  G L  GAW
Sbjct: 1676 ALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAW 1735

Query: 1377 ACFDEFNRIDLEVLSVVAQQI-----LTIQRGINAGADILMFEGTELKLDPTCAV---FI 1428
               ++ +++   +LS + Q++     L       A  +    + T+ +L  +       +
Sbjct: 1736 LLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHV 1795

Query: 1429 TMNPGY-------AGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKI 1481
            ++  GY       A  S +P NL  L R VA+ +PD   +AE+ L   G   A  ++ ++
Sbjct: 1796 SVRLGYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRL 1855

Query: 1482 VATYRLCSEQLSSQHHYDYGM------RAVKSVLTAAGNLKLKYPNE---NEEILLLRSI 1532
               + L  E +S        +        ++++       K + P      EE  LLRS 
Sbjct: 1856 SKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSP 1915

Query: 1533 IDVNLPKFLSHDLPLFEGITSDLFPGVK--LPKP-DYNDLLAAIKDNCASMNLQMTAFFS 1589
            +   L     H+L    G+   LFP     L +P  Y  +   + +    + L  +    
Sbjct: 1916 LFSILNGLHLHNL---RGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDIL 1972

Query: 1590 EKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVL------AGALNDICEKGLMEENKVQIT 1643
              + Q+ + +    G +++G    GKT+ +  L        A+ D   +G      V+IT
Sbjct: 1973 GSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGC---QPVEIT 2029

Query: 1644 VLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRK-----------WLIFD 1692
             L P  ++  +  G  +     W  G+     RA        +K           W+I D
Sbjct: 2030 HLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICD 2087

Query: 1693 GPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYM 1752
            G  +  W++++  +L +  +L L SG+ I   P   L+ E  D    SP  V  C +++ 
Sbjct: 2088 GASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWC 2147

Query: 1753 EPHMLGWRPLMLSWVNLLPASVSVIQKEF--IMGLFDRMVPVSVEF---------IRKHT 1801
                  W+ ++ + +  LP    +  +    +  + + +VP ++ F         ++ H 
Sbjct: 2148 GGEQT-WQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHG 2206

Query: 1802 KE---LSPTSDTNLVRSLMNLIDCFMD------------DFADEVKLKERNDRETY---- 1842
            ++         T++ R L +L+D  +              ++D V    R+ + ++    
Sbjct: 2207 QQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRS 2266

Query: 1843 --------------SLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNT 1888
                           L    FLF+LIW  GA        +F  I    +   IS      
Sbjct: 2267 QVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPS----RFWPIFDTFIRDSIS------ 2316

Query: 1889 FKLQSGTEQTSSKALTVPF---PEKGTIYDY--QFVTEGIGKWEPWIKKLKEAPPIPKDV 1943
             +L +  E   S AL       PE GT+  +  Q+++  I                 K  
Sbjct: 2317 -RLSNYPEPPPS-ALVFDLHVSPEDGTLVPFTGQYLSSHI-----------------KGT 2357

Query: 1944 MFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLL 2003
            +      P++ T R   +++LL +  +P +  G   TGKS ++   L+   +  IY P+ 
Sbjct: 2358 L--GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV-EVLVEPHHPYIYSPIH 2414

Query: 2004 INFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPARE-VYGAQPPIEL 2062
              FS+          +  +     +          ++  ++D+++   +     QP +E 
Sbjct: 2415 PAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLET 2474

Query: 2063 LRQWLDHWNWYDLKDCSMIKLVDIQ----IMCAMGPPGGGRNPVTPRYMRHFNIITINEF 2118
            LRQ +D   +      S ++L  +Q     +  +  PG    P+ PR  R F ++ +   
Sbjct: 2475 LRQAMDGTVYAH----STLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESM 2530

Query: 2119 SDKSMYTIFSRILTWHLEICYKFP--DEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHY 2176
            +  ++      I+   LE   +FP  +    L   +V  ++  ++      +P+P   HY
Sbjct: 2531 TQATLLERHVPIIQAWLE---RFPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHY 2587

Query: 2177 LFNLRDFSRV-------------------------------IQGVCLSRPETTETTEVIK 2205
             F+L   S +                               ++G CL+       T  + 
Sbjct: 2588 HFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLT---VMMATRNVV 2644

Query: 2206 RLWVHEVLRVYYDRLLDNTDRSW 2228
            RLW+HE  R + DRL    +RS+
Sbjct: 2645 RLWLHEAQRTFCDRLDSPRERSY 2667



 Score =  103 bits (257), Expect = 3e-21
 Identities = 169/767 (22%), Positives = 304/767 (39%), Gaps = 113/767 (14%)

Query: 3010 LYVIKLSEPDYVRTLENCIQFGTPVLLENVG-----EELDPILEPLLLKQTFKQGGSTCI 3064
            L V+  ++P+    L+     G PVLL NV      EEL  +L+   L            
Sbjct: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQL------------ 3711

Query: 3065 RLGDSTIEYAPDFRFYITTKLR----NPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120
                S  +  P F  Y++T L           E    + +L+  +  E +++Q+L  ++ 
Sbjct: 3712 ----SPPQVQPGFCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILC 3767

Query: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180
            +E P+LE   Q L ++  +  + ++  E+++L +L        + +   K L +      
Sbjct: 3768 REYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNP---KRQKPAKFLRNIVRAQG 3824

Query: 3181 EISQKQEVAEETE-KKIDTTRMG--YRPIAIHSSILFFSLADLANIEPMYQYSLTWFINL 3237
            ++ Q +   EE E +K+    +   YRP+  H   +  +L+ L N+ P++  S   ++ +
Sbjct: 3825 KLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAV 3884

Query: 3238 FILSIENSEKSEI-----LAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLL 3292
               ++++ +  EI     LA  L  L+ H T  L  +   +L      L      + LL 
Sbjct: 3885 TKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQ 3944

Query: 3293 HERAINKAEWRFLLTGGIGLD------NPYANLC--TWLPQKSWDEICRLDDLPAFKTIR 3344
                 ++ E R  L  G+          P +++    WL  K+W E   L+ LP F  + 
Sbjct: 3945 ATGKASELE-RLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLC 4003

Query: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404
                     W+             P    +  +  Q++++ R LRP+ +   L +F  + 
Sbjct: 4004 ASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSL 4063

Query: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAAL------LKFADDQGYGGSKL 3458
            LGR  ++   +     F  S    P++ +L P   P A L       K A     G  +L
Sbjct: 4064 LGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQL 4122

Query: 3459 SSLSLG-QGQGPIAMKM--LEKAVKEGTWVVLQNCHLATSWMPTLEKVCEEL-------- 3507
              ++LG +   P+++ +  L +A+ EG W+VL NCHL   W   L ++  EL        
Sbjct: 4123 QVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVA 4182

Query: 3508 ---------SPES-----THPDFRMWL--TSYPSPNFPVSVLQNGVKM-TNEAPKGLRAN 3550
                      PES      H DFR+WL   +  S + P  + Q+ + +  N++ +     
Sbjct: 4183 DLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE----- 4237

Query: 3551 IIRSYLMDPISDPEFFGSCKKPEEFKK--LLYGLCFFHALVQERRKFGPLGWNIPYEFNE 3608
             +   L+D +   +     + P +     LL+GL     L   R +     W+   +   
Sbjct: 4238 -LGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWS---QVTL 4293

Query: 3609 TDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELV 3668
            T +  +  QL   L+     P  A++ +     YGG + D  DR  L S+     +P   
Sbjct: 4294 TQVLQTQDQLWASLSN----PRAAMQELAASVFYGGPLGDTEDREALISLTQACLSP--- 4346

Query: 3669 ENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANAD 3715
                    SSG +  P       +   +    L P PE+  ++A A+
Sbjct: 4347 --------SSGSWVQP-------HTPQSLLATLMPLPELRELDAMAE 4378



 Score =  102 bits (253), Expect = 1e-20
 Identities = 166/747 (22%), Positives = 281/747 (37%), Gaps = 116/747 (15%)

Query: 2321 EHISRISRILKQPRSHALLV-GVGGSGRQSVTRLAAHMADYSVFQVE------ISKGYDT 2373
            +H++R+ R+L +PR H LL+ G  G+GR +   LA+ +     F +       I +    
Sbjct: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRD 2929

Query: 2374 TEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEI 2433
              WH  +  + +  A     GV L T         L  +  L  +G  P  +   +   I
Sbjct: 2930 ASWHAGM--LSQPVALLVPSGVDLTT---------LHRLLALATSGSFPGQYTEADLDRI 2978

Query: 2434 CDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRK---FP 2490
             +    L R+    KQ     + L       C S LH+      IGD   ++      F 
Sbjct: 2979 GE---HLPRENLGVKQNIKKEMVLQRFHQQVC-SHLHLFFL---IGDKQAHKQLPSTLFL 3031

Query: 2491 ALVNCCT--IDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSF 2548
             L+   T  ID ++ W + AL  VA   LE  + S  + DG          S   ++K+ 
Sbjct: 3032 RLLQLATASIDRYEPWDQAALAKVAQHHLEGAQ-SVPLDDGSWKY-PDLQASIPSVAKAM 3089

Query: 2549 -FVELQRYNY----------VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDS 2597
              + L   +Y          VTP ++L+ + TF +L ++   ++    +R +  LE L  
Sbjct: 3090 ALIHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRM 3149

Query: 2598 ASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMA 2657
               +  T    +  L  QLK + K +      +E+  +   +  +  +  E +    A  
Sbjct: 3150 LIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQ 3209

Query: 2658 SKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGI 2717
              A++ + +A L     + ++ L  L  L   D   ++S ++PP  V  V +A+C     
Sbjct: 3210 RDALQAQREAFLE---QMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMC----- 3261

Query: 2718 KADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPN-P 2776
              D     TG        W  AK+LL    F Q L  + K+ I  +   +I+ + I   P
Sbjct: 3262 --DLFHHETG--------WASAKQLLCTEDFYQELVFFPKEKITDS--ELIKLHLILKAP 3309

Query: 2777 DFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQA 2836
                  +R  S  A  L  W+ A+  Y        P  + L   E  L        ++QA
Sbjct: 3310 GMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLT-------REQA 3362

Query: 2837 ALKEVQDKLARLQDTLELN---KQKKADLENQVDLCSKKLERAE-------QLIGGLGGE 2886
             L   Q    + Q+TLE N    +   D +   +  +K L +A+        +   L   
Sbjct: 3363 RLGYYQ---FQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTP 3419

Query: 2887 KTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSD 2946
               W+    +L    + + GD L+ S  + YLG F    RQ    EW  LC+G       
Sbjct: 3420 MRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGP 3479

Query: 2947 D---------------------------CSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGI 2979
            D                            S++  L        W+    P    +   G+
Sbjct: 3480 DDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGL 3539

Query: 2980 II-----MNARRWPLMIDPQSQANKWI 3001
            ++      ++ RWPL++DP ++A  W+
Sbjct: 3540 LLRSPTHYSSCRWPLLLDPSNEALIWL 3566


>gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens]
          Length = 457

 Score =  137 bits (344), Expect = 3e-31
 Identities = 92/366 (25%), Positives = 184/366 (50%), Gaps = 18/366 (4%)

Query: 165 YYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDS---IVTLSDEMREDYLLSVRKS 221
           Y Y+   +++  + P++  WL+H+L L+P+ LK   +    + +L +E+  D+  S+++ 
Sbjct: 96  YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155

Query: 222 IVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAV 281
           +V  VL  P  K  + +   LP     ++    PW  S++ A + I  +L+ ++PTM  +
Sbjct: 156 LVQSVLVKPPVKSLEDEGGPLPESPVGLDY-SNPWHSSYVQARNQIFSNLHIIHPTMKML 214

Query: 282 LDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQ 341
           LDL +T F    L+D       +  ++  S +  +     +A+E ++  W+P+V N++  
Sbjct: 215 LDLGYTTFADTVLLDFTGI-RAKGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF-- 271

Query: 342 GNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPG 401
              KK+   G    KL++F++C + LM+ QL+DL   +++ F  L   P D  R    P 
Sbjct: 272 --TKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-DPKDQQRL---PI 325

Query: 402 FIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLK 461
           F + L  D+D ++F P   D  D  L++ + + +A+  V  + + L       +  T L 
Sbjct: 326 FKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELP 385

Query: 462 PIILNEIVDAHKEKIKEVIMKESVAPTEHLRLY-DKYDFLITRKAERDVDNFLAENHSYE 520
             +L+  VD     +K  + +      +H   Y +KY++L+   A  +++ F  E+H+++
Sbjct: 386 EHVLHWAVDT----LKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFD 441

Query: 521 KIIDEI 526
           +  +E+
Sbjct: 442 EYTEEL 447


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 46.2 bits (108), Expect = 7e-04
 Identities = 105/548 (19%), Positives = 208/548 (37%), Gaps = 96/548 (17%)

Query: 2368 SKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEI------ 2421
            SK  DT    + L+  L +  E E + V        KEES    V ++L   E       
Sbjct: 534  SKLTDTLVSKQQLEQRLMQLMESEQKRVN-------KEESLQMQVQDILEQNEALKAQIQ 586

Query: 2422 ---PNLFALDEKQEICDKMRQLDRQRDKT-KQTDGSPIALFNMFIDHCRSQLHVVLAMSP 2477
                 + A      + +++ ++  ++DK  KQT+ S  +      D   S+   +  +  
Sbjct: 587  QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER----DRLTSKEEELKDIQN 642

Query: 2478 IGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSF 2537
            +    +  ++K  AL N               QA A+  LE+++ S  ++D  I + +  
Sbjct: 643  MNFLLKAEVQKLQALAN--------------EQAAAAHELEKMQQSVYVKDDKIRLLEEQ 688

Query: 2538 HTSTIDLSKSFFVELQRYNYVTPTSYLELISTF-----KLLLEKKRSEVMKMKKRYEVGL 2592
                I      F  L   N    +   +L +       K ++E+    + +  ++ +   
Sbjct: 689  LQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVE 748

Query: 2593 EKLDSASSQVATMQMELEALHPQLKVASKEVDEMM-----------IMIEKESVEVAKTE 2641
            E L++   QVAT + EL A+  +    +KEV ++            ++ E + V   K  
Sbjct: 749  ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808

Query: 2642 KIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPP 2701
            KI   +E +  E  +   A K++   DL   +  L+  +  +    AQ +++   ++   
Sbjct: 809  KIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866

Query: 2702 AGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIP 2761
              +K   E +  +K +  +K  D   +GK ++D              LQ  +E  K ++ 
Sbjct: 867  NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQD--------------LQEENESLKAHVQ 912

Query: 2762 PAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAE 2821
                           +     ++ AS+A++           ++++  ++  K+ +L   E
Sbjct: 913  ---------------EVAQHNLKEASSASQ-----------FEELEIVLKEKENELKRLE 946

Query: 2822 GELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQV---DLCSKKLERAEQ 2878
              LK     L  K   L++VQD+    +  +E  KQ+     +     +   K +   E+
Sbjct: 947  AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREK 1006

Query: 2879 LIGGLGGE 2886
             I GL  E
Sbjct: 1007 EISGLWNE 1014


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 46.2 bits (108), Expect = 7e-04
 Identities = 105/548 (19%), Positives = 208/548 (37%), Gaps = 96/548 (17%)

Query: 2368 SKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEI------ 2421
            SK  DT    + L+  L +  E E + V        KEES    V ++L   E       
Sbjct: 534  SKLTDTLVSKQQLEQRLMQLMESEQKRVN-------KEESLQMQVQDILEQNEALKAQIQ 586

Query: 2422 ---PNLFALDEKQEICDKMRQLDRQRDKT-KQTDGSPIALFNMFIDHCRSQLHVVLAMSP 2477
                 + A      + +++ ++  ++DK  KQT+ S  +      D   S+   +  +  
Sbjct: 587  QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER----DRLTSKEEELKDIQN 642

Query: 2478 IGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSF 2537
            +    +  ++K  AL N               QA A+  LE+++ S  ++D  I + +  
Sbjct: 643  MNFLLKAEVQKLQALAN--------------EQAAAAHELEKMQQSVYVKDDKIRLLEEQ 688

Query: 2538 HTSTIDLSKSFFVELQRYNYVTPTSYLELISTF-----KLLLEKKRSEVMKMKKRYEVGL 2592
                I      F  L   N    +   +L +       K ++E+    + +  ++ +   
Sbjct: 689  LQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVE 748

Query: 2593 EKLDSASSQVATMQMELEALHPQLKVASKEVDEMM-----------IMIEKESVEVAKTE 2641
            E L++   QVAT + EL A+  +    +KEV ++            ++ E + V   K  
Sbjct: 749  ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808

Query: 2642 KIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPP 2701
            KI   +E +  E  +   A K++   DL   +  L+  +  +    AQ +++   ++   
Sbjct: 809  KIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866

Query: 2702 AGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIP 2761
              +K   E +  +K +  +K  D   +GK ++D              LQ  +E  K ++ 
Sbjct: 867  NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQD--------------LQEENESLKAHVQ 912

Query: 2762 PAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAE 2821
                           +     ++ AS+A++           ++++  ++  K+ +L   E
Sbjct: 913  ---------------EVAQHNLKEASSASQ-----------FEELEIVLKEKENELKRLE 946

Query: 2822 GELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQV---DLCSKKLERAEQ 2878
              LK     L  K   L++VQD+    +  +E  KQ+     +     +   K +   E+
Sbjct: 947  AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREK 1006

Query: 2879 LIGGLGGE 2886
             I GL  E
Sbjct: 1007 EISGLWNE 1014


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 46.2 bits (108), Expect = 7e-04
 Identities = 105/548 (19%), Positives = 208/548 (37%), Gaps = 96/548 (17%)

Query: 2368 SKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEI------ 2421
            SK  DT    + L+  L +  E E + V        KEES    V ++L   E       
Sbjct: 534  SKLTDTLVSKQQLEQRLMQLMESEQKRVN-------KEESLQMQVQDILEQNEALKAQIQ 586

Query: 2422 ---PNLFALDEKQEICDKMRQLDRQRDKT-KQTDGSPIALFNMFIDHCRSQLHVVLAMSP 2477
                 + A      + +++ ++  ++DK  KQT+ S  +      D   S+   +  +  
Sbjct: 587  QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER----DRLTSKEEELKDIQN 642

Query: 2478 IGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSF 2537
            +    +  ++K  AL N               QA A+  LE+++ S  ++D  I + +  
Sbjct: 643  MNFLLKAEVQKLQALAN--------------EQAAAAHELEKMQQSVYVKDDKIRLLEEQ 688

Query: 2538 HTSTIDLSKSFFVELQRYNYVTPTSYLELISTF-----KLLLEKKRSEVMKMKKRYEVGL 2592
                I      F  L   N    +   +L +       K ++E+    + +  ++ +   
Sbjct: 689  LQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVE 748

Query: 2593 EKLDSASSQVATMQMELEALHPQLKVASKEVDEMM-----------IMIEKESVEVAKTE 2641
            E L++   QVAT + EL A+  +    +KEV ++            ++ E + V   K  
Sbjct: 749  ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808

Query: 2642 KIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPP 2701
            KI   +E +  E  +   A K++   DL   +  L+  +  +    AQ +++   ++   
Sbjct: 809  KIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866

Query: 2702 AGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIP 2761
              +K   E +  +K +  +K  D   +GK ++D              LQ  +E  K ++ 
Sbjct: 867  NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQD--------------LQEENESLKAHVQ 912

Query: 2762 PAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAE 2821
                           +     ++ AS+A++           ++++  ++  K+ +L   E
Sbjct: 913  ---------------EVAQHNLKEASSASQ-----------FEELEIVLKEKENELKRLE 946

Query: 2822 GELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQV---DLCSKKLERAEQ 2878
              LK     L  K   L++VQD+    +  +E  KQ+     +     +   K +   E+
Sbjct: 947  AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREK 1006

Query: 2879 LIGGLGGE 2886
             I GL  E
Sbjct: 1007 EISGLWNE 1014


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 44.3 bits (103), Expect = 0.002
 Identities = 62/331 (18%), Positives = 133/331 (40%), Gaps = 16/331 (4%)

Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617
            VT  + L+ +   +++LE +  ++ K KK  E  + +  +  ++       L  L  + +
Sbjct: 967  VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026

Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677
                +++E +   EK+  E+ KT + ++ D T  ++Q    +A   E    LA     L+
Sbjct: 1027 AMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQ 1086

Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737
            +ALA ++   AQ    +K ++   + +  + E +   +  +          G+++E    
Sbjct: 1087 AALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKT 1146

Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDF----VPEKIRNASTAAEGL 2793
              +  L      Q L    +  +     NI++K            + E  +  S A E L
Sbjct: 1147 ELEDTLDSTAAQQELRSKREQEV-----NILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL 1201

Query: 2794 CKWVIAMDSYDKVAKIVAPKKIKLAAAEGEL----KIAMDGLRKKQAALKEVQDKLARLQ 2849
             +    ++   +V   +   K  L    GEL    K+ + G    +   K+V+ +L  LQ
Sbjct: 1202 AE---QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQ 1258

Query: 2850 DTLELNKQKKADLENQVDLCSKKLERAEQLI 2880
                  ++ + +L ++V     +L+    L+
Sbjct: 1259 VKFNEGERVRTELADKVTKLQVELDNVTGLL 1289


>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
          Length = 1093

 Score = 43.9 bits (102), Expect = 0.003
 Identities = 125/601 (20%), Positives = 230/601 (38%), Gaps = 82/601 (13%)

Query: 2484 NRLRKFPALV-NCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTI 2542
            NRL  F  L  +CC+ D F+     ++Q++ SR + EI   +E+      +      S+ 
Sbjct: 305  NRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIVNSST 364

Query: 2543 DLSKSFFV-----ELQRYNYVTPTSYLEL-----------------------ISTFKLLL 2574
              SK+        E      V PT   E+                       I+  + +L
Sbjct: 365  PKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVL 424

Query: 2575 EKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKE----------VD 2624
            +K   +    + + E   EK D   + V  +  +LE    QL   SKE          + 
Sbjct: 425  DKVAEQCEPAESQPEALSEKEDVCKT-VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLK 483

Query: 2625 EMMIMIEKESVEVAK-----TEKIVKADETI---ANEQAMASKAIKDECDADLAGALPIL 2676
            + M  +++ES  ++      T++I +A++ +     E+  A K IK+    +LA  L   
Sbjct: 484  DEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKN-IKEELATRLNSS 542

Query: 2677 ESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKA-DKIPDPTGS--GKKIE 2733
            E+A    D L  +D  +   M+      K  +    I+K ++A DK  +   +   KK++
Sbjct: 543  ETA----DLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVK 598

Query: 2734 DFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKN-----YIPNPDFVPEKIRNAST 2788
            +     + L   +   + + +  ++NI      + R+         + D + EK R+   
Sbjct: 599  ELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQA 658

Query: 2789 AAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARL 2848
            A +   K +  +       K  A K  +  A E  L   M    +  AAL++ Q++  + 
Sbjct: 659  ALDSAYKELTDLH------KANAAKDSE--AQEAALSREMKAKEELSAALEKAQEEARQQ 710

Query: 2849 QDTLELN-KQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGD 2907
            Q+TL +     +  L+      ++K +     IG L        +   EL Q   + T  
Sbjct: 711  QETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRP 770

Query: 2908 ILIS-SGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIA 2966
            +L     + A LG        +QT  W  L K       +  +L+    E     T  + 
Sbjct: 771  LLRQIENLQATLG--------SQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELL 822

Query: 2967 GLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLS--EPDYVRTL 3024
                   S+++   ++           +S+ N+  K +E  N+ Y ++L   + +YVRTL
Sbjct: 823  ANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCK-LEDENNRYQVELENLKDEYVRTL 881

Query: 3025 E 3025
            E
Sbjct: 882  E 882


>gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]
          Length = 1016

 Score = 41.6 bits (96), Expect = 0.016
 Identities = 28/117 (23%), Positives = 60/117 (51%), Gaps = 8/117 (6%)

Query: 2777 DFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRK--- 2833
            D + E++  A  A   LC      +   +V++I++  + ++  +EG+L++   GL     
Sbjct: 465  DLLEEQVAGAMQACGQLCSGAPG-EQDSQVSEILSALERRVLDSEGQLRLVGSGLHTVEA 523

Query: 2834 ----KQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGE 2886
                +QA L+ +Q+ + RLQD ++   +  A+   +++L + +L + E L+   G E
Sbjct: 524  AGEARQATLEGLQEVVGRLQDRVDAQDETAAEFTLRLNLTAARLGQLEGLLQAHGDE 580


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 40.8 bits (94), Expect = 0.027
 Identities = 61/328 (18%), Positives = 129/328 (39%), Gaps = 7/328 (2%)

Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617
            VT  + ++      LLLE + S++ K +K  E  L +  S +++       L  L  + +
Sbjct: 999  VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1058

Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677
                ++++ +   EK   E+ K ++ +  + +   EQ +  +   +E  A L      L+
Sbjct: 1059 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1118

Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737
            +ALA  +        ++KS++   A +    E +   +  +          G+++E   G
Sbjct: 1119 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1178

Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWV 2797
              +  L      Q L    +  +      +  +  I   +   +++R     A G     
Sbjct: 1179 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI--HEAAVQELRQRHGQALGELAEQ 1236

Query: 2798 IAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ 2857
            +      K A      ++ L A   EL+  +  L   Q A +E + +  RL+  L+  + 
Sbjct: 1237 LEQARRGKGA--WEKTRLALEAEVSELRAELSSL---QTARQEGEQRRRRLELQLQEVQG 1291

Query: 2858 KKADLENQVDLCSKKLERAEQLIGGLGG 2885
            +  D E      ++KL+RA+  +  + G
Sbjct: 1292 RAGDGERARAEAAEKLQRAQAELENVSG 1319


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 40.8 bits (94), Expect = 0.027
 Identities = 61/328 (18%), Positives = 129/328 (39%), Gaps = 7/328 (2%)

Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617
            VT  + ++      LLLE + S++ K +K  E  L +  S +++       L  L  + +
Sbjct: 991  VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1050

Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677
                ++++ +   EK   E+ K ++ +  + +   EQ +  +   +E  A L      L+
Sbjct: 1051 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1110

Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737
            +ALA  +        ++KS++   A +    E +   +  +          G+++E   G
Sbjct: 1111 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1170

Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWV 2797
              +  L      Q L    +  +      +  +  I   +   +++R     A G     
Sbjct: 1171 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI--HEAAVQELRQRHGQALGELAEQ 1228

Query: 2798 IAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ 2857
            +      K A      ++ L A   EL+  +  L   Q A +E + +  RL+  L+  + 
Sbjct: 1229 LEQARRGKGA--WEKTRLALEAEVSELRAELSSL---QTARQEGEQRRRRLELQLQEVQG 1283

Query: 2858 KKADLENQVDLCSKKLERAEQLIGGLGG 2885
            +  D E      ++KL+RA+  +  + G
Sbjct: 1284 RAGDGERARAEAAEKLQRAQAELENVSG 1311


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 40.8 bits (94), Expect = 0.027
 Identities = 61/328 (18%), Positives = 129/328 (39%), Gaps = 7/328 (2%)

Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617
            VT  + ++      LLLE + S++ K +K  E  L +  S +++       L  L  + +
Sbjct: 1032 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1091

Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677
                ++++ +   EK   E+ K ++ +  + +   EQ +  +   +E  A L      L+
Sbjct: 1092 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1151

Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737
            +ALA  +        ++KS++   A +    E +   +  +          G+++E   G
Sbjct: 1152 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1211

Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWV 2797
              +  L      Q L    +  +      +  +  I   +   +++R     A G     
Sbjct: 1212 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI--HEAAVQELRQRHGQALGELAEQ 1269

Query: 2798 IAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ 2857
            +      K A      ++ L A   EL+  +  L   Q A +E + +  RL+  L+  + 
Sbjct: 1270 LEQARRGKGA--WEKTRLALEAEVSELRAELSSL---QTARQEGEQRRRRLELQLQEVQG 1324

Query: 2858 KKADLENQVDLCSKKLERAEQLIGGLGG 2885
            +  D E      ++KL+RA+  +  + G
Sbjct: 1325 RAGDGERARAEAAEKLQRAQAELENVSG 1352


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 39.3 bits (90), Expect = 0.080
 Identities = 42/194 (21%), Positives = 87/194 (44%), Gaps = 32/194 (16%)

Query: 2506 EDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPT---- 2561
            E+A + +A R  E  E  E +   C  + K+ H    ++ +   V+++R N         
Sbjct: 1387 EEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEI-EDLMVDVERSNAAAAALDKK 1445

Query: 2562 --SYLELISTFKLLLEKKRSEV--------------MKMKKRYEVGLEKLDSASSQVATM 2605
              ++ ++++ +K   E+ +SE+               K+K  YE  LE L++   +   +
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNL 1505

Query: 2606 QMELEALHPQLKVASK---EVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKA-- 2660
            Q E+  L  QL  + K   E++++   +E E +E+     + +A+ ++ +E+    +A  
Sbjct: 1506 QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA--LEEAEASLEHEEGKILRAQL 1563

Query: 2661 ----IKDECDADLA 2670
                IK E +  LA
Sbjct: 1564 EFNQIKAEIERKLA 1577


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 149,013,420
Number of Sequences: 37866
Number of extensions: 6729292
Number of successful extensions: 19748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 18256
Number of HSP's gapped (non-prelim): 1111
length of query: 4024
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3902
effective length of database: 13,627,866
effective search space: 53175933132
effective search space used: 53175933132
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 72 (32.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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