BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] (4024 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 8087 0.0 gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 4036 0.0 gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 3158 0.0 gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 2631 0.0 gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2454 0.0 gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 2092 0.0 gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2056 0.0 gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1980 0.0 gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1946 0.0 gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 1945 0.0 gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 1941 0.0 gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1918 0.0 gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 1909 0.0 gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1900 0.0 gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1308 0.0 gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1268 0.0 gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 937 0.0 gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 478 e-134 gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 225 6e-58 gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens] 137 3e-31 gi|118498356 kinectin 1 isoform a [Homo sapiens] 46 7e-04 gi|118498368 kinectin 1 isoform c [Homo sapiens] 46 7e-04 gi|33620775 kinectin 1 isoform a [Homo sapiens] 46 7e-04 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 44 0.002 gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 44 0.003 gi|5901944 elastin microfibril interfacer 1 [Homo sapiens] 42 0.016 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 41 0.027 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 41 0.027 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 41 0.027 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 39 0.080 >gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] Length = 4024 Score = 8087 bits (20983), Expect = 0.0 Identities = 4024/4024 (100%), Positives = 4024/4024 (100%) Query: 1 MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPS 60 MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPS Sbjct: 1 MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPS 60 Query: 61 FHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKE 120 FHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKE Sbjct: 61 FHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKE 120 Query: 121 RENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPM 180 RENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPM Sbjct: 121 RENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPM 180 Query: 181 EDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTD 240 EDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTD Sbjct: 181 EDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTD 240 Query: 241 ELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEF 300 ELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEF Sbjct: 241 ELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEF 300 Query: 301 HNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESF 360 HNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESF Sbjct: 301 HNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESF 360 Query: 361 FNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELS 420 FNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELS Sbjct: 361 FNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELS 420 Query: 421 DYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVI 480 DYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVI Sbjct: 421 DYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVI 480 Query: 481 MKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTS 540 MKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTS Sbjct: 481 MKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTS 540 Query: 541 IKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALST 600 IKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALST Sbjct: 541 IKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALST 600 Query: 601 PPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWY 660 PPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWY Sbjct: 601 PPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWY 660 Query: 661 GRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLK 720 GRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLK Sbjct: 661 GRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLK 720 Query: 721 KAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNY 780 KAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNY Sbjct: 721 KAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNY 780 Query: 781 RAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPL 840 RAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPL Sbjct: 781 RAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPL 840 Query: 841 IQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYS 900 IQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYS Sbjct: 841 IQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYS 900 Query: 901 LEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYE 960 LEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYE Sbjct: 901 LEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYE 960 Query: 961 KQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDI 1020 KQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDI Sbjct: 961 KQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDI 1020 Query: 1021 MRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELL 1080 MRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELL Sbjct: 1021 MRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELL 1080 Query: 1081 EILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQV 1140 EILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQV Sbjct: 1081 EILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQV 1140 Query: 1141 EKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIP 1200 EKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIP Sbjct: 1141 EKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIP 1200 Query: 1201 MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260 MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD Sbjct: 1201 MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260 Query: 1261 DSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL 1320 DSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL Sbjct: 1261 DSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL 1320 Query: 1321 HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFD 1380 HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFD Sbjct: 1321 HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFD 1380 Query: 1381 EFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSEL 1440 EFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSEL Sbjct: 1381 EFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSEL 1440 Query: 1441 PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY 1500 PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY Sbjct: 1441 PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY 1500 Query: 1501 GMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVK 1560 GMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVK Sbjct: 1501 GMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVK 1560 Query: 1561 LPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYR 1620 LPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYR Sbjct: 1561 LPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYR 1620 Query: 1621 VLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFAS 1680 VLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFAS Sbjct: 1621 VLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFAS 1680 Query: 1681 SVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVAS 1740 SVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVAS Sbjct: 1681 SVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVAS 1740 Query: 1741 PATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKH 1800 PATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKH Sbjct: 1741 PATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKH 1800 Query: 1801 TKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGAS 1860 TKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGAS Sbjct: 1801 TKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGAS 1860 Query: 1861 CTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVT 1920 CTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVT Sbjct: 1861 CTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVT 1920 Query: 1921 EGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGT 1980 EGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGT Sbjct: 1921 EGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGT 1980 Query: 1981 GKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMV 2040 GKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMV Sbjct: 1981 GKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMV 2040 Query: 2041 VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRN 2100 VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRN Sbjct: 2041 VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRN 2100 Query: 2101 PVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLY 2160 PVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLY Sbjct: 2101 PVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLY 2160 Query: 2161 KEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRL 2220 KEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRL Sbjct: 2161 KEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRL 2220 Query: 2221 LDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRED 2280 LDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRED Sbjct: 2221 LDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRED 2280 Query: 2281 TNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLV 2340 TNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLV Sbjct: 2281 TNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLV 2340 Query: 2341 GVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTD 2400 GVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTD Sbjct: 2341 GVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTD 2400 Query: 2401 TQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNM 2460 TQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNM Sbjct: 2401 TQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNM 2460 Query: 2461 FIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEI 2520 FIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEI Sbjct: 2461 FIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEI 2520 Query: 2521 EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE 2580 EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE Sbjct: 2521 EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE 2580 Query: 2581 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT 2640 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT Sbjct: 2581 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT 2640 Query: 2641 EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSP 2700 EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSP Sbjct: 2641 EKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSP 2700 Query: 2701 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI 2760 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI Sbjct: 2701 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI 2760 Query: 2761 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA 2820 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA Sbjct: 2761 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA 2820 Query: 2821 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI 2880 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI Sbjct: 2821 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI 2880 Query: 2881 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR 2940 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR Sbjct: 2881 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR 2940 Query: 2941 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW 3000 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW Sbjct: 2941 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW 3000 Query: 3001 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG 3060 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG Sbjct: 3001 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG 3060 Query: 3061 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA Sbjct: 3061 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120 Query: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN Sbjct: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180 Query: 3181 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL 3240 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL Sbjct: 3181 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL 3240 Query: 3241 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA 3300 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA Sbjct: 3241 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA 3300 Query: 3301 EWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDS 3360 EWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDS Sbjct: 3301 EWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDS 3360 Query: 3361 LEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKA 3420 LEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKA Sbjct: 3361 LEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKA 3420 Query: 3421 FGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVK 3480 FGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVK Sbjct: 3421 FGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVK 3480 Query: 3481 EGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMT 3540 EGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMT Sbjct: 3481 EGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMT 3540 Query: 3541 NEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGW 3600 NEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGW Sbjct: 3541 NEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGW 3600 Query: 3601 NIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILN 3660 NIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILN Sbjct: 3601 NIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILN 3660 Query: 3661 KFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQ 3720 KFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQ Sbjct: 3661 KFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQ 3720 Query: 3721 SETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQS 3780 SETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQS Sbjct: 3721 SETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQS 3780 Query: 3781 MNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKS 3840 MNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKS Sbjct: 3781 MNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKS 3840 Query: 3841 YPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPI 3900 YPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPI Sbjct: 3841 YPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPI 3900 Query: 3901 DLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLK 3960 DLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLK Sbjct: 3901 DLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLK 3960 Query: 3961 PCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLC 4020 PCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLC Sbjct: 3961 PCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLC 4020 Query: 4021 QLNS 4024 QLNS Sbjct: 4021 QLNS 4024 >gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] Length = 4116 Score = 4036 bits (10466), Expect = 0.0 Identities = 2071/3957 (52%), Positives = 2724/3957 (68%), Gaps = 110/3957 (2%) Query: 129 VNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPMEDSWLEHV 188 ++V++QQ+ +++S KP+ E D+ RYYYY+ +GI D +AP E + + Sbjct: 209 LDVMLQQEMEMESKEK------KPS----ESDLERYYYYLTNGIRKDMIAPEEGEVMVRI 258 Query: 189 LDLVPQHLKV---FTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKT--DELP 243 L+ L +V L E DY S+ KSIVD++L DP E+ K+ + +P Sbjct: 259 SKLISNTLLTSPFLEPLMVVLVQEKENDYYCSLMKSIVDYILMDPMER---KRLFIESIP 315 Query: 244 AHRAEMEI-LPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEFHN 302 + I P PW + +A + +HL+ +NP ML + +LW F+ LR V E Sbjct: 316 RLFPQRVIRAPVPWHSVYRSAKKWNEEHLHTVNPMMLRLKELWFAEFRDLRFVRTAEILA 375 Query: 303 CQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKK----KQLPTGDSSAKLE 358 + L+ F ++I +H A +TLL W P ++ + DSS +E Sbjct: 376 GKLPLQPQEFWDVIQKHCLEAHQTLLNKWIPTCAQLFTSRKEHWIHFAPKSNYDSSRNIE 435 Query: 359 SFFNCAAALMTLQLQDLTLVSMQDFTDL---------IAQPPDSVRAFEHPGFIMRLILD 409 +F A+ M+LQL++L + S++D L +P ++ F +++L + Sbjct: 436 EYFASVASFMSLQLRELVIKSLEDLVSLFMIHKDGNDFKEPYQEMKFFIPQLIMIKLEVS 495 Query: 410 NDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVE-------------TKLYSKWESKSK 456 I F P ++ + + +IK + +P+++ + K + Sbjct: 496 EPIIVFNPSFDGCWELIRDSFLEIIKNSNGIPKLKYIPLKFSFTAAAADRQCVKAAEPGE 555 Query: 457 P------TTLKPI----ILNEIVDAHKEKIKE-------VIMKESVAPTEHLRLYDKYDF 499 P T + + +L V+A ++ + + V K V P ++L +Y KY Sbjct: 556 PSMHAAATAMAELKGYNLLLGTVNAEEKLVSDFLIQTFKVFQKNQVGPCKYLNVYKKYVD 615 Query: 500 LITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRA 559 L+ AE+++ FL ENH + + +I +K EI +I T+ L MF + L Sbjct: 616 LLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNI-TVPLAMFCLDATALNHD 674 Query: 560 LVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEV 619 L +RA + L+ +++ NT +C+++ IA+K P NT EL+ + +++K Sbjct: 675 LCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEFLKKSSA 734 Query: 620 TDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIE 679 + +L ++L D+ L FL++Y AD+ ++ +IF+ R ++ K + Sbjct: 735 VTVFKLRRQLRDASERLEFLMDY-----ADLPY---------QIEDIFDNSRNLLLHKRD 780 Query: 680 QYQEGLKLRCERFVEELESYAKQSEEF--YSFGDLQDVQRYLKKAQILNGKLDLAADKIE 737 Q + L RC F LE Y ++ E F ++++ ++K L+ L+ A + E Sbjct: 781 QAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAEFE 840 Query: 738 QFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVE 797 N EEE S YP + + PY +L+ TA EFS W GP +N +Q+ Sbjct: 841 LINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIA 900 Query: 798 ADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAM 857 +IGN WR YKL KT D P + + V+ K++ FKQ+IP++ + CNPG++ RHW+ + Sbjct: 901 EEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQI 960 Query: 858 SAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEF 917 S IVGY ++P++ + +S+ L+ ++++ E I AASKEYSLEK +++M +W V F Sbjct: 961 SEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTF 1020 Query: 918 VIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEIL 977 YR+T T IL ++D+IQMLLDDH+IKTQTM GSPFIKP E + R+WE KL+ +Q+ L Sbjct: 1021 SFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNL 1080 Query: 978 DEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTID 1037 D WLK QATWLYLEPIFSS DI++QMPEEGR+F VD W+ +M ++D +L Sbjct: 1081 DAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQP 1140 Query: 1038 RMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLK 1097 RM E+L+++N LLE I KGLN+YLEKKRLFFPRFFFLSNDELLEILSETKDP RVQPHLK Sbjct: 1141 RMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLK 1200 Query: 1098 KCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK 1157 KCFEGIAK+EFT+ L+I M SSE E V I+ I A A+G VEKWL ++E++M+ S+ + Sbjct: 1201 KCFEGIAKLEFTDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMRE 1260 Query: 1158 VTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQI 1217 V G AY K R +WV WPGQ V+CVS IFWT+EV A + L +LK N QI Sbjct: 1261 VIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQA--LAENTLLDFLKKSNDQI 1318 Query: 1218 DDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQEN 1277 IV LVRGKLS R+TLGAL V+DVHARDV++ L + +SD +DF+W+SQLRYYW Sbjct: 1319 AQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAK 1378 Query: 1278 HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTET 1337 ++ ++I YGYEYLGNSPRLVITPLTDRCYRTL GAL L+LGGAPEGPAGTGKTET Sbjct: 1379 DVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTET 1438 Query: 1338 TKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQI 1397 TKDLAKA+AKQCVVFNCSDGLDY A+GKFFKGL GAWACFDEFNRI++EVLSVVAQQI Sbjct: 1439 TKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQI 1498 Query: 1398 LTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPD 1457 L+IQ+ I +FEGTEL L+PTCAVFITMNPGYAGR+ELPDNLKALFRTVAMMVPD Sbjct: 1499 LSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPD 1558 Query: 1458 YAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL 1517 YA+I EI LYS GF+ +R L+ KIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL Sbjct: 1559 YALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL 1618 Query: 1518 KYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNC 1577 KYP ENE +LLLR+++DVNL KFL+ D+PLF+GI SDLFPGV LPKPDY L + DN Sbjct: 1619 KYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNI 1678 Query: 1578 ASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEE 1637 M LQ +F KI+Q+YEMM+VRHG+MIVG+P GGKTSAY+VLA AL D+ MEE Sbjct: 1679 KKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEE 1738 Query: 1638 NKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDA 1697 V+ ++NPK++TMGQLYG FD VSHEW DGVLA +FR ASS++ DRKW+IFDGPVDA Sbjct: 1739 FAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDA 1798 Query: 1698 VWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHML 1757 +WIENMNTVLDDNKKLCLMSGEIIQM+ +M+LIFEP DLE ASPATVSRCGMIYMEPH L Sbjct: 1799 IWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQL 1858 Query: 1758 GWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLM 1817 GW+PL S+++ LP+S++ KE + +F +V +EF R H K + TS +L S+M Sbjct: 1859 GWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMM 1918 Query: 1818 NLIDCFMDDF----ADEVKLKE-RNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKI 1872 L +D+ +E++L E + ++ + L+G+FLFSL+W+V + D R KF+ Sbjct: 1919 RLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVF 1978 Query: 1873 LRELMESPISDRTR-NTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIK 1931 R L+ + R + KL FPE+G+IYD+ F+ + G WE W + Sbjct: 1979 FRNLIMGMDDNHPRPKSVKLTKNN----------IFPERGSIYDFYFIKQASGHWETWTQ 2028 Query: 1932 KL-KEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFL 1990 + KE +P +E+I+PT++T R S ++ H+ P +FVGPTGTGKS NFL Sbjct: 2029 YITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFL 2088 Query: 1991 LNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPA 2050 L+ L K Y P INFSA+T+A QTQ+I+MSKLD+RRKG+FGPP+GK+ VVFVDD+NMPA Sbjct: 2089 LH-LPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA 2147 Query: 2051 REVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHF 2110 +EVYGAQPPIELLRQW+DH W+D KD + + +VD+ ++ AMGPPGGGRN +T R+ RH Sbjct: 2148 KEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHL 2207 Query: 2111 NIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPT 2170 NII+IN F D + IFS I+ WH F FL +V T T+Y++A++N LPT Sbjct: 2208 NIISINAFEDDILTKIFSSIVDWHFG--KGFDVMFLRYGKMLVQATKTIYRDAVENFLPT 2265 Query: 2171 PAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLI 2230 P+KSHY+FNLRDFSRVIQGV L + E RLW+HEV RV+YDRL+D DR Sbjct: 2266 PSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFF 2325 Query: 2231 NYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVD 2290 N ++E N + ++ + G + D++RSL F D+ P+ + Y EI D+ Sbjct: 2326 NMVKETTSNCFKQTIEKVL--IHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLK 2383 Query: 2291 NLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSV 2350 L +++E +LEE+NNISK PM+LV+FRFAIEHISRI R+LKQ + H LLVG+GGSGRQS Sbjct: 2384 QLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSA 2443 Query: 2351 TRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLE 2410 +L+ M Y ++Q+EI+K Y +W EDLK I+ + VFLF D QIK+ESF+E Sbjct: 2444 AKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVE 2503 Query: 2411 DVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLH 2470 D++ LLN G++PN+F DEK +I +KM+ R + ++ + +P++++N FI+ +++ Sbjct: 2504 DINMLLNTGDVPNIFPADEKADIVEKMQ--TAARTQGEKVEVTPLSMYNFFIERVINKIS 2561 Query: 2471 VVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGC 2530 LAMSPIGDAFRNRLR FP+L+NCCTIDWFQSWP DAL+ VA++FLE++E+ + IR Sbjct: 2562 FSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEV 2621 Query: 2531 IDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEV 2590 + MCK F S LS ++ +L+R+NYVTPTSYLELI TFK LL KR EV M+ RY Sbjct: 2622 VSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLT 2681 Query: 2591 GLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETI 2650 GL+KLD A+SQVA MQ EL AL PQL + S+E +MM+ IE E+ E + +V+ADE Sbjct: 2682 GLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKE 2741 Query: 2651 ANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEA 2710 AN A ++ IK+EC+ DLA A+P LE+ALAALDTL DI++VKSM++PP VKLVME+ Sbjct: 2742 ANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMES 2801 Query: 2711 ICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRK 2770 ICI+KG+K ++ PDP+GSGK IED+WG +K++LGD++FL+SL YDKDNIPP M IR+ Sbjct: 2802 ICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRE 2861 Query: 2771 NYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDG 2830 +I +P+F P I+N S+A EGLCKWV AM+ YD+VAK+VAPK+ +L AEG+L M Sbjct: 2862 RFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQK 2921 Query: 2831 LRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRW 2890 L +K+A LK V D+L L D E KK DLE +++CS+KL RAE+LI GLGGEK RW Sbjct: 2922 LNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRW 2981 Query: 2891 SHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSDDCSL 2950 + A +LG Y NLTGD+L+SSG VAYLGAFT YR +W CK + IP D SL Sbjct: 2982 TEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSL 3041 Query: 2951 MGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSL 3010 TLG+ + IR W IAGLP DSFSIDNGII+ N+RRW LMIDP QANKWIKNMEKAN L Sbjct: 3042 SHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKL 3101 Query: 3011 YVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDST 3070 VIK S+ +Y+R LEN +Q GTPVL+EN+GEELD +EP+LLK TFKQ G +RLG++ Sbjct: 3102 AVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENI 3161 Query: 3071 IEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEK 3130 IEY+ DF+ YITT+LRNPHYLPE +VKV LLNFMITP G+QDQLLGIV A+E+P+LEE+K Sbjct: 3162 IEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKK 3221 Query: 3131 QALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAE 3190 LI++ A+NK+ LKEIEDKILEVLS S+GNILEDETAIK+LSSSK L+ EIS+KQ+VA Sbjct: 3222 NQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVAS 3281 Query: 3191 ETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEI 3250 TE +ID TRMGY+P+A+HS+ +FF ++DLANIEPMYQYSLTWFINL++ S+ +S KSE Sbjct: 3282 MTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEE 3341 Query: 3251 LAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGI 3310 L R++ + DHFT S+Y NVCRSLFEKDKLLFS LTI ++ ++ I + W FLLTGGI Sbjct: 3342 LNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGI 3401 Query: 3311 GLDNPYANLC-TWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFP 3369 LDNPY N WL +K+W EI R LP + + WK +YDS PH E P Sbjct: 3402 ALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLP 3461 Query: 3370 EEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAP 3429 W+ + ++M+I+RCLRPDK++P ++EFI +G+ +IE P FDL ++ DS+CCAP Sbjct: 3462 GSWK-FSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAP 3520 Query: 3430 LIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQN 3489 LIFVLSP ADPMA LLKFADD G GG++ ++SLGQGQGPIA KM+ A+K+GTWVVLQN Sbjct: 3521 LIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQN 3580 Query: 3490 CHLATSWMPTLEKVCEE-LSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLR 3548 CHLA SWMPTLEK+CEE + PEST+ FR+WLTSYPS FPVS+LQNG+KMTNE PKGLR Sbjct: 3581 CHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLR 3640 Query: 3549 ANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNE 3608 AN++RSYL DPISDP FF SC K ++K+L+GLCFFHA+VQERR FGPLGWNIPYEFNE Sbjct: 3641 ANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNE 3700 Query: 3609 TDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELV 3668 +DLRIS+ Q+ MFLN Y+E+P++AL Y+TGECNYGGRVTDD DRR L S+L+ F+ E + Sbjct: 3701 SDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKE-I 3759 Query: 3669 ENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFD 3728 E Y Y++PP G ++SYI+Y + LP+T PE+FG++ NADITKD ET LF+ Sbjct: 3760 EEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFE 3819 Query: 3729 NILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQE 3788 +LLT R +G KS EVV E+A DIL KLP +FD+E M+ YP Y +SMNTVL QE Sbjct: 3820 GVLLTLPRQSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQE 3879 Query: 3789 MGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLG 3848 + RFN+L K +R S +N+ +AIKG +MS++LEEV +S+L K+P MW KSYPSLKPLG Sbjct: 3880 LIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLG 3939 Query: 3849 SYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYE 3908 YV D LARL F Q+W + GPP VFW+SGF+FTQ+FLTG QNYARKYTIPID +GF++E Sbjct: 3940 GYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFE 3999 Query: 3909 VM-EDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADI 3967 V ++ ++ PEDG +I GLFL+GA W+RK ++ ES PKILYD +P++WLKP + A Sbjct: 4000 VTPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMF 4059 Query: 3968 PKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLNS 4024 + YV P+YKTS RRG LSTTGHSTN+V+++ LP+D P++HWI RGVA LCQL++ Sbjct: 4060 LHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN 4116 >gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] Length = 4265 Score = 3158 bits (8187), Expect = 0.0 Identities = 1680/3685 (45%), Positives = 2353/3685 (63%), Gaps = 111/3685 (3%) Query: 385 DLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVE 444 DLI P R ++P FIM L+LD+ + + L + LN++D I A VP++E Sbjct: 645 DLINSP---YRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLE 701 Query: 445 TKLYSKWESKSKPTTLKPIILNE-IVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITR 503 KL + S L+ + L+E +V+ + I + K + + + Y KY L Sbjct: 702 -KLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN 760 Query: 504 KAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKR 563 + + + +++ + + + + E + + +I +G F ++ + + ++L K+ Sbjct: 761 DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK 820 Query: 564 ADIICGKLLAKMFRD-HQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDM 622 + +L + ++ H+EV++ +C+EF I+ K P + EL E++ +++ + + Sbjct: 821 RKALATSVLDILAKNLHKEVDS-ICEEFRSISRKIYEKPNSIEELAELREWMKGIPER-L 878 Query: 623 IELEQRLVDSKNCLAFLIEYV-NFSPADMRLNNSVFQWYGR-MGEIFEEHRKIIKEKIEQ 680 + LE+R+V + + E++ N S D W + +G+I ++ ++++ E+ Sbjct: 879 VGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDE-EK 937 Query: 681 YQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFN 740 +++ + F E+LE F ++ + + + +L +N Sbjct: 938 FRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYN 997 Query: 741 AEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADI 800 E F + Y + ++ PYL L+ TA ++ +W P ++ +Q+E ++ Sbjct: 998 NRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNV 1057 Query: 801 GNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAI 860 ++ ++K K F D P + +R+++E+FK +IPLIQ + NPG+R RHWE +S Sbjct: 1058 VEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQ 1117 Query: 861 VGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIH 920 + ++P + T + L+MNL+ +I+ ++E A KEY++E+A++KM EW + F + Sbjct: 1118 ININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVL 1177 Query: 921 SYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEW 980 Y+ T T+IL S DE LLDDHI+ TQ M SP+ KP+E+++ WE KL L QE+L+EW Sbjct: 1178 PYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEW 1237 Query: 981 LKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML 1040 L Q +WLYLEPIFSS DI Q+P E +R+ +++ W+ IM++ +++ V+ V + RML Sbjct: 1238 LNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRML 1297 Query: 1041 ERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCF 1100 + L+ N++L+L+ KGL+EYLE KR FPRF+FLS+DELLEILS+TKDPT VQPHL+KCF Sbjct: 1298 DSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCF 1357 Query: 1101 EGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTG 1160 E IA++ F E L+ITHM S+EGE V+L I + VE WL E+ER M S+H + Sbjct: 1358 ENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSS---NVEDWLREVERSMKASVHDIIE 1414 Query: 1161 DATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDI 1220 A AY R WV +WPGQ + Q +WT EV A+ G + + + C +Q+ D+ Sbjct: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLC-QQLSDL 1473 Query: 1221 VTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLE 1280 V LVRGKLS R L AL+V++VHA+DV+S L+++N+ +DF+W+SQLRYYW N L Sbjct: 1474 VALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLY 1533 Query: 1281 TKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKD 1340 + +NA YGYEYLGNS RLVITPLTDRCY TL GALHL GGAP GPAGTGKTETTKD Sbjct: 1534 IRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKD 1593 Query: 1341 LAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTI 1400 L KA+A Q VVFNCSD LD++A+GKFFKGL S GAWACFDEFNRID+EVLSVVAQQI TI Sbjct: 1594 LGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTI 1653 Query: 1401 QRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAM 1460 Q+ + MFEG E+ L P+CAVFITMNPGYAGR+ELPDNLKALFR VAMMVPDYAM Sbjct: 1654 QKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAM 1713 Query: 1461 IAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYP 1520 I EI LYS GF A L+ KI T++L SEQLSSQ HYD+GMRAVK+V++AAGNLK + P Sbjct: 1714 ITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENP 1773 Query: 1521 NENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASM 1580 + NEE++ LR+I DVN+PKFL DL LF GI SDLFP +K DY L AI++ C + Sbjct: 1774 SMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNS 1833 Query: 1581 NLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDI-----CEKGLM 1635 NL+ F K +Q+YE +VRHG M+VG GK++ YRVLA A+ + G+ Sbjct: 1834 NLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMY 1893 Query: 1636 EENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPV 1695 E V VLNPKS+TMGQLYG+FD ++HEW+DG+ + RA A + ++KW +FDGPV Sbjct: 1894 EA--VNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPV 1951 Query: 1696 DAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPH 1755 DA+WIENMNTVLDDNKKLCL SGEII+++ M ++FE DL VASPATVSRCGM+Y+EP Sbjct: 1952 DAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPS 2011 Query: 1756 MLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRS 1815 +LG P + W+ LP + ++ F LF + S+ F+R KE+ +++ NL S Sbjct: 2012 ILGLMPFIECWLRKLPPLLKPYEEHF-KALFVSFLEESISFVRSSVKEVIASTNCNLTMS 2070 Query: 1816 LMNLIDCFMDDFADEVKLKERNDRETYSLLEGI---FLFSLIWSVGASCTDDDRLKFNKI 1872 L+ L+DCF F LK+ + ++E I F+FSLIWSVGA+ R F+ Sbjct: 2071 LLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHW 2130 Query: 1873 LRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIG-------- 1924 LR ME+ + LT+ FPE+G ++DY+ GI Sbjct: 2131 LRLKMEN---------------------EQLTLLFPEEGLVFDYRLEDAGISGTNDSEDE 2169 Query: 1925 ----KWEPWIKKLKEAPPIPK--DVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978 K W+K + + P D + IIVPT+DT++ S L+++L T++KP + +GPT Sbjct: 2170 EEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPT 2229 Query: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038 GTGK++ I++ LL L + Y + FSA+T+A QTQ+ + SKLDKRRKGVFGPPLG+ Sbjct: 2230 GTGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRN 2288 Query: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIK-LVDIQIMCAMGPPGG 2097 + F+DD+NMPA E YGAQPPIELLRQW+DH WYD K K LVDI +CAMGPPGG Sbjct: 2289 FIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGG 2348 Query: 2098 GRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHL-----EICYKF----PDEFLDL 2148 GRN VTPR MRHFN ++ E + S IFS IL L E Y+ Sbjct: 2349 GRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHF 2408 Query: 2149 TTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLW 2208 T +V T+ +Y LLPTPAKSHY FNLRD S+V QG+ ++ P E + RLW Sbjct: 2409 TEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLW 2468 Query: 2209 VHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSL 2268 HE RV+ DRL++ DRSW ++L+ M E + F ++ + + Sbjct: 2469 YHENCRVFRDRLVNEEDRSWF----DQLLKRCM-EQWEVTFNKVC----------PFQPI 2513 Query: 2269 MFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISR 2328 ++ DF P + +Y I + ++E ++E+YN I+ + LVLF A+ HI RISR Sbjct: 2514 LYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISR 2573 Query: 2329 ILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCA 2388 L+Q +ALL+GVGGSGR S+TRLA+HMA+Y FQ+E+SK Y +EW +D+K +L K Sbjct: 2574 TLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAG 2633 Query: 2389 EGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTK 2448 + FLF+DTQIK ESFLED++N+LN+G+IPNL+ DE+ +I MR +++ Sbjct: 2634 LQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQG--- 2690 Query: 2449 QTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDA 2508 + L + RS +H+VL MSPIG+ FR RLR+FP+LVNCCTIDWF WP +A Sbjct: 2691 -LQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEA 2749 Query: 2509 LQAVASRFLEEI---EMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLE 2565 L++VA+ FL EI E S+E G I +C H S + EL R+NYVTP SYLE Sbjct: 2750 LKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLE 2809 Query: 2566 LISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDE 2625 L+ F +L+ +K+ E+ K R + GL+KL S VA MQ +LE++HP L+ A+K+ Sbjct: 2810 LLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTML 2869 Query: 2626 MMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDT 2685 M I+ ++ +T V+ +E ANE+A ++AI D+ DL ALP L++ALA+L Sbjct: 2870 TMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRN 2929 Query: 2686 LTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGD 2745 L D+T V++M+ PP GVKLV+EA+CI+KGIK K+P G K++D+W P K LL D Sbjct: 2930 LNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEK-PGTKVDDYWEPGKGLLQD 2988 Query: 2746 M-RFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804 FL+SL ++DKDNI + I+ YI N +F P I S A +C+WV AM Y Sbjct: 2989 PGHFLESLFKFDKDNIGDVVIKAIQP-YIDNEEFQPATIAKVSKACTSICQWVRAMHKYH 3047 Query: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864 VAK V PK+ L A+ +L + L + + L+EV+D +A +Q KK +LE Sbjct: 3048 FVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELEL 3107 Query: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924 + + C ++L RA +LI GL EK RW T L + N++GD+L+++G VAYLG FT Sbjct: 3108 KCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQ 3167 Query: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984 YR W + ++P + + +L+GTLG V IR+W IAGLP+D+ S++NG+I + Sbjct: 3168 YRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFS 3227 Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044 +RW IDPQSQANKWIKNMEK N L V KLS+ D++R++EN I+FG P LLENVGEELD Sbjct: 3228 QRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELD 3287 Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104 P LEP+LLKQT+KQ G+T ++LGD+ I Y DFR YITTKL NPHY PE S K+TL+NF Sbjct: 3288 PALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFT 3347 Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164 ++P G++DQLLG VVA+ERPDLEE K LI+ A+ +++LK+IED+IL LSSSEGN ++ Sbjct: 3348 LSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVD 3407 Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224 D IK+L +SK A EI K +AE+TEK ID TRM Y P+AI + ILFF ++DLAN++ Sbjct: 3408 DMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVD 3467 Query: 3225 PMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSF 3284 PMYQYSL WF+N+F+ I NSE+++ L KR+ + + TYSLY NVCRSLFEK KL+F+F Sbjct: 3468 PMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAF 3527 Query: 3285 CLTINLLLHERAINKAEWRFLLTGG---IGLDNPYANLCTWLPQKSWDEICRLDDLPAFK 3341 L + ++++E IN++EWR+LL+GG I +NP + WL ++W +I L +LP F Sbjct: 3528 LLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPD---WLSDRAWRDILALSNLPTFS 3584 Query: 3342 TIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFI 3401 + +F++ ++ ++DSLEPH E P W+ ++FQ++L++RCLR DKV +Q+F+ Sbjct: 3585 SFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFV 3644 Query: 3402 INRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSL 3461 L FIEP +L+ F DSN PLIFVLSPG DP A L KFA++ + KLS++ Sbjct: 3645 ATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAI 3703 Query: 3462 SLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLT 3521 SLGQGQGP A M+ +++ G WV QNCHLA SWMP LE++ E ++P+ H DFR+WLT Sbjct: 3704 SLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLT 3763 Query: 3522 SYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYG 3581 S PS FPVS+LQNG KMT E P+G+RAN+++SY +F SC K EFK LL Sbjct: 3764 SLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSY---SSLGEDFLNSCHKVMEFKSLLLS 3820 Query: 3582 LCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECN 3641 LC FH ERRKFGPLG+NIPYEF + DLRI + QL MFL++Y+++PY+ L+Y GE N Sbjct: 3821 LCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEIN 3880 Query: 3642 YGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYF-VPPSGDHKSYIEYTKTLP 3700 YGGRVTDDWDRR + +IL F+NP+++ + ++ + +SGIY +PP+ D Y+ Y K+LP Sbjct: 3881 YGGRVTDDWDRRCIMNILEDFYNPDVL-SPEHSYSASGIYHQIPPTYDLHGYLSYIKSLP 3939 Query: 3701 LTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKL 3760 L PEIFG++ NA+IT Q+ET L I+ Q +S+ AG++ +E+V +V +IL K+ Sbjct: 3940 LNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKV 3999 Query: 3761 PNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDL 3820 P +++ M +YP Y +SMNTVLVQE+ R+N+LL+ I + ++ KA+KGL VMS+ L Sbjct: 4000 PEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQL 4059 Query: 3821 EEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFF 3880 E + +S+ N +PE+W K+YPSLKPL S+V D L RL FLQ W + G P VFW+SGFFF Sbjct: 4060 ELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFF 4119 Query: 3881 TQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRK 3938 QAFLTG QN+ARK+ I ID + FD++VM + E P+ G +IHGLFL+GA W+ + Sbjct: 4120 PQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPE 4179 Query: 3939 IKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVI 3998 +LAES PK LY + V+WL P + Y+ P+YKT R G LSTTGHSTN+VI Sbjct: 4180 AFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVI 4239 Query: 3999 AMTLPSDQPKEHWIGRGVALLCQLN 4023 A+ +P+ QP+ HWI RGVAL+C L+ Sbjct: 4240 AVEIPTHQPQRHWIKRGVALICALD 4264 >gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] Length = 4158 Score = 2631 bits (6819), Expect = 0.0 Identities = 1491/3738 (39%), Positives = 2180/3738 (58%), Gaps = 205/3738 (5%) Query: 400 PGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLY----------S 449 P F+ L+L ++ FEP L D++D L + V VP + Y + Sbjct: 511 PMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINN 570 Query: 450 KWESKSKPTTLK-PIILNEIVDAHK--EKIKEVIMKESVAPTEHLRLYDKYDFLITRKAE 506 K E K+ T + + + H +IKE I + + ++K+ Sbjct: 571 KLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQIFFKENES 630 Query: 507 RDVDNFLAENHSYEKIIDEICKYQKLIEE-IQYTSIKTIRLGMFEMHCEELIRALVKRAD 565 D+ + +++ KY K ++ + + + L + + L+R + + Sbjct: 631 LDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTR---LLREKLIPSP 687 Query: 566 IICGKLLAKMF-RDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIE 624 + C ++L M R ++ + E + K P T E + ++ +++ E Sbjct: 688 LRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQ-----E 742 Query: 625 LEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEG 684 + L D N + + Y + F + M R I + + + Sbjct: 743 RIESLEDEGNIVTQM--YKLMEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKSVGDRESS 800 Query: 685 LKLRCERFVEELESYAKQSEEFYSFGD---LQDVQRYLKKAQ-ILNGKLDLAAD---KIE 737 +K C +LE + E + D+ K + ILN + AD + Sbjct: 801 IKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAF 860 Query: 738 QFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVE 797 Q+ + ++ F S + +++ L L+++ E+ + W + + ++P+ + Sbjct: 861 QYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLN 920 Query: 798 ADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAM 857 + Y + + +LEK + ++ +++ KVE K+ +P+I + NP L+ RHW A+ Sbjct: 921 GQVSKYAKFVTQLEKGLPPN----SVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAI 976 Query: 858 SAIVGYPLQPSD-DSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVE 916 V L ++ T+ +++ + + IS AS E +LE ++K+ W E Sbjct: 977 EQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTE 1036 Query: 917 FVIHSYRET-GTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQE 975 FVI +R++ FIL D+IQ+LLDD I T+ S ++ P + ++ EW+ +L L + Sbjct: 1037 FVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQ 1096 Query: 976 ILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVT 1035 L+EWL Q WLYLE IF++PDI Q+P E + F VDK+W++IMR V + + L T Sbjct: 1097 TLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAAT 1156 Query: 1036 IDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPH 1095 +LE + +N LL+ I K L YLE KR+ FPRF+FLSNDELLEIL++T++P VQPH Sbjct: 1157 QPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPH 1216 Query: 1096 LKKCFEGIAKVEFT-------------------ETLDITHMKSSEGEVVELIEIISTAKA 1136 L+KCF+ I+K+EF T DI M S EGE V L + + KA Sbjct: 1217 LRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGL---KA 1273 Query: 1137 RGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWV-RDWPGQTVLCVSQIFWTKEV 1195 RG VE+WL ++E M S+ ++ A Y R +WV P Q +L VSQI W +++ Sbjct: 1274 RGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDL 1333 Query: 1196 ----QTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLS 1251 +T I+AL+ + K +++ + +V+G L +R L AL+ +DVHARD+++ Sbjct: 1334 TECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVT 1393 Query: 1252 SLVKKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDR 1309 LV+ + F+W QLRYYW + + +M + YGYEYLG PRLVITPLTDR Sbjct: 1394 ELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDR 1453 Query: 1310 CYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKG 1369 CY L GAL L LGGAP GPAGTGKTETTKDLAKA+A QCVVFNCSDGLDY +G+FF G Sbjct: 1454 CYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSG 1513 Query: 1370 LLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFIT 1429 L GAW CFDEFNRID+EVLSV+AQQ++TI+ A MFEG E+KL TCA FIT Sbjct: 1514 LAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFIT 1573 Query: 1430 MNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCS 1489 MNPGYAGR+ELPDNLKALFR AMMVP+YA+IAE++LYS GF +++ L+ K+ Y+LCS Sbjct: 1574 MNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCS 1633 Query: 1490 EQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFE 1549 EQLS Q HYD+GMRAVKSVL AG+LK + P+ NE+++L+R++ D NLPKFL+ D LF Sbjct: 1634 EQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFS 1693 Query: 1550 GITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVG 1609 GI SDLFPGV++P+ DY L + I D NLQ K++Q YE M+VRHG M+VG Sbjct: 1694 GIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVG 1753 Query: 1610 EPFGGKTSAYRVLAGALNDICEKGLMEE--NKVQITVLNPKSVTMGQLYGQFDSVSHEWS 1667 GGKT+ YR+LA L ++ + G+ V+ VLNPKS+TMG+LYG+ ++++ EW Sbjct: 1754 PTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWK 1813 Query: 1668 DGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQM 1727 DG++A+S RA + + D KW+I DGPVDA+WIENMNTVLDDNK LCL + E I+++PQ+ Sbjct: 1814 DGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQI 1873 Query: 1728 NLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFD 1787 +++FE DL VASPATVSRCGM++++P L W P + +W+ + ++ +E+I+ LF Sbjct: 1874 HMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQ 1933 Query: 1788 RMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEG 1847 R V + FI K + P D + V +L L++ + D V L + L + Sbjct: 1934 RYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILG-KDGVNLAMEQTKLNTILCQ- 1991 Query: 1848 IFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPF 1907 F+F +WS+G + T++ F+ +R + R N+ L S Sbjct: 1992 TFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWS-------------- 2037 Query: 1908 PEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTT 1967 F T+ + WE I K +DV F E++VPT DT+RY LME L Sbjct: 2038 ------IHMDFDTKRLDPWERIIPTFK----YNRDVPFFEMLVPTTDTVRYGYLMEKLLA 2087 Query: 1968 HQKPSIFVGPTGTGKSVYITNFLLNQLNKEI-YKPLLINFSAQTTAAQTQNIVMSKLDKR 2026 + +F G TG GKSV I LLN++ + Y P+ +NFSAQT++A+TQ I+ SKL+++ Sbjct: 2088 VKHSVLFTGITGVGKSV-IAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERK 2146 Query: 2027 RKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDI 2086 RK + G P KR+V+FVDD+NMP + YG+QPPIELLRQ+ D +YD ++ D+ Sbjct: 2147 RKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDV 2206 Query: 2087 QIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFL 2146 I+ A PPGGGRNPVTPR++RHF+++ + S+ S+ IF IL L FP Sbjct: 2207 TIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLS---DFPPAVK 2263 Query: 2147 DLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKR 2206 + IV ++ +Y + +LLPTPAKSHY+FNLRD S+ +QG+ P T I R Sbjct: 2264 QTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFR 2323 Query: 2207 LWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLR 2266 L+ HE RV++DRL++N D+ +Y IL + F F N ++ D ++ Sbjct: 2324 LFCHECQRVFHDRLINNEDK----HYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIK 2379 Query: 2267 SLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRI 2326 + D Y ++ D++ +++ +L++YN + K + LV F+ AIEH+SRI Sbjct: 2380 -------FGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRI 2432 Query: 2327 SRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRK 2386 +R+++Q R +ALLVGVGG+G+QS+TRLAAH+ Y Q+E+S+GY+ +HEDL+ + + Sbjct: 2433 ARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKM 2492 Query: 2387 CAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDK 2446 + VFLFTDTQI E FLED++N+LN+GE+PNLF DE +++ L R + Sbjct: 2493 AGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQV------LAATRPR 2546 Query: 2447 TKQ---TDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQS 2503 K+ ++G+ +F FI R +LH+VL MSP+G+AFR+R R FP+LVNCCTIDWF Sbjct: 2547 AKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQ 2606 Query: 2504 WPEDALQAVASRFLEEIEM-SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTS 2562 WP +AL +V+ F +++ +EE+++ MC + H S +++ ++ EL+R Y TPTS Sbjct: 2607 WPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTS 2666 Query: 2563 YLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKE 2622 YLELI+ + +L +KR +++ + R + GL KL + V M+++L AL P L S++ Sbjct: 2667 YLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSED 2726 Query: 2623 VDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAA 2682 V+ +M + + + V+ DE A +A ++AI D+ DL ALP L++A A Sbjct: 2727 VEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKA 2786 Query: 2683 LDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRL 2742 LD+L DI+ ++ PP V VMEAI IL K D W AK+L Sbjct: 2787 LDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPD---------------WPSAKQL 2831 Query: 2743 LGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDS 2802 LGD FL+ L EYDK+NI P + ++K YI NPDFVPEK+ S A + +C WV AMD Sbjct: 2832 LGDSNFLKRLLEYDKENIKPQILAKLQK-YINNPDFVPEKVEKVSKACKSMCMWVRAMDL 2890 Query: 2803 YDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADL 2862 Y +V K+V PK+ KL AA+ EL I M LR+KQA L++V+D++ LQD + +K L Sbjct: 2891 YSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESL 2950 Query: 2863 ENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFT 2922 + L +L RA +L L E+ RW + + + N+TG++ I++ VAY GAFT Sbjct: 2951 AKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFT 3010 Query: 2923 STYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIM 2982 + YRQ+ + W C+ +IP SL+ LG+ IR WN GLP D S +NGI++ Sbjct: 3011 AQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVT 3070 Query: 2983 NARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEE 3042 RRWPLMIDPQ QAN+WI+N E + L +IKL++ +++R LEN I+ G PVLLE + E Sbjct: 3071 QGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKET 3130 Query: 3043 LDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLN 3102 LDP LEP+LLKQ F GG IRLGDS I+Y +FRFY+TTK+ NPHYLPE +KVT++N Sbjct: 3131 LDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIIN 3190 Query: 3103 FMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNI 3162 F +T G++DQLL VV E+P LEE++ LI++ +K QLK IE+KIL +L +SEGNI Sbjct: 3191 FTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNI 3250 Query: 3163 LEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLAN 3222 L++E I L SK + I + E AE TE+ I+ R YRP+A S+++F +A L+ Sbjct: 3251 LDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSE 3310 Query: 3223 IEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLF 3282 I+PMYQYSL +F LF +IE S K+E L +RL +L + + YVNV R LFE+ KL++ Sbjct: 3311 IDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIY 3370 Query: 3283 SFCLTINLLLHERAINKAEWRFLLTGGIGL--DNPYANLCTWLPQKSWDEICRLDD-LPA 3339 SF L + ++ + ++ AEW F L G GL + P WLP +W C L++ P Sbjct: 3371 SFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPV 3430 Query: 3340 FKTIRRE------------------------FMRLKDGWKKVYDSLEPHHEVFPEEWEDK 3375 F + + + ++K K + E H+ + W Sbjct: 3431 FHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQ---DPWSAG 3487 Query: 3376 ANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLS 3435 + F ++++I+C + +KV+ L +F+I LG+ FIE PP DL + D +C PL+F+LS Sbjct: 3488 LSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILS 3547 Query: 3436 PGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATS 3495 G+DPM A +FA + GY ++ S+SLGQGQGPIA KM++ A+K G WV LQNCHLA S Sbjct: 3548 TGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVS 3606 Query: 3496 WMPTLEKVCEELS-PESTHPD-FRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIR 3553 WM +E++ + + P+S D FR++L+S PS FPV+VLQN VK+TNE PKGLRANI R Sbjct: 3607 WMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRR 3666 Query: 3554 SYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRI 3613 ++ P FF ++++++++G+CFFHA++QER+KFGPLGWNI YEFN++D Sbjct: 3667 AFTE---MTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDREC 3723 Query: 3614 SVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDY 3673 ++ L ++ + ++P++AL Y+TGE YGGRVTD WD+R LR+IL +FF+PE +E DY Sbjct: 3724 ALLNLKLYCKE-GKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLE-EDY 3781 Query: 3674 KFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLT 3733 K+ SGIYF P + + + +Y + LPL PEIFGM+ NA++ ET L + IL Sbjct: 3782 KYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEV 3841 Query: 3734 QSRSA-GAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQ----SMNTVLVQE 3788 Q RS+ G KS+DE+V E+ + + ++P ++E A Q S+ TVL QE Sbjct: 3842 QPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQE 3901 Query: 3789 MGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLG 3848 + RFN LLK I S + KAI G VMS ++E+V +S LN ++P +W +YPSLKPLG Sbjct: 3902 VDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLG 3961 Query: 3849 SYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYE 3908 S+V D + R F+ W + G P +W+SGFFF Q FLTG QN+ARKY +PID L F Y Sbjct: 3962 SWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYS 4021 Query: 3909 VME-----------------------DKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAES 3945 V+ D E PEDGV +HG+F+D + W+ K + ++ Sbjct: 4022 VIPTYRDQAAVIEAAKTVQFGQELPMDMELP-SPEDGVLVHGMFMDASRWDDKEMVIEDA 4080 Query: 3946 HPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSD 4005 P + +PV+ +P + P Y PLYKT R G LSTTGHSTNFV+ + LPS Sbjct: 4081 LPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSK 4139 Query: 4006 QPKEHWIGRGVALLCQLN 4023 + K++WI +G ALLCQL+ Sbjct: 4140 RSKDYWIAKGSALLCQLS 4157 >gi|75677365 dynein heavy chain domain 3 [Homo sapiens] Length = 4427 Score = 2454 bits (6360), Expect = 0.0 Identities = 1401/3693 (37%), Positives = 2107/3693 (57%), Gaps = 192/3693 (5%) Query: 399 HPGFIMRLILDNDT------IKFEPELSDYIDIFLNVYDVMIKAVSF---VPRVETKLYS 449 +P F + +IL ND ++F P L + ++ + + +S +P + TK Sbjct: 860 NPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK--- 916 Query: 450 KWESKSKPTTLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDV 509 + +PI + V E IK++ + S T + L Y L T R++ Sbjct: 917 ------RKLHREPI---QTVVEQDEDIKKIQTQISSGMTNNASLLQNY--LKTWDMYREI 965 Query: 510 -----DNFLAENHSYEKI-------IDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELI 557 D+F+ H Y+++ + +I +Y ++ +Q T + + C L Sbjct: 966 WEINKDSFI---HRYQRLNPPVSSFVADIARYTEVANNVQKEETVT-NIQFVLLDCSHLK 1021 Query: 558 RALVKRADIICGKLLAKMFRDHQ-----EVNTRLCDEFERIAEKALSTPPNTAELMEMKA 612 +LV+ + K A + R+ E++T L + E+I S PP T E + + Sbjct: 1022 FSLVQHCNEWQNKF-ATLLREMAAGRLLELHTYLKENAEKI-----SRPPQTLEELGVSL 1075 Query: 613 YIQKVEVTDMIELEQRLVDSKNCLAFLIEY-VNFSPADMRLNNSVFQWYGRMGEIFEEHR 671 + D+ +E ++ A L +Y V + + + +S+ + + + + Sbjct: 1076 QLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSK 1135 Query: 672 KIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDL 731 +++K+ E+++ GL + F ++ + E+F G Y+ + + Sbjct: 1136 QMLKKHKEKFKTGLIHSADDFKKKAHTLL---EDFEFKGHFTSNVGYMSALDQITQVRAM 1192 Query: 732 AADKIEQFNAEEEAFGWLPSVYPQRKKIQD---GLNPYLRLYETAVEFSSNYRAWTEGPY 788 E+ N+ G P K +Q+ L+ +++E A ++ N+ W G + Sbjct: 1193 LMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRF 1252 Query: 789 HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848 + + +E +R L KL K + D + + T RSK+E FK+ +PLI + NP Sbjct: 1253 LILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIET--TRSKIEQFKRTMPLISDLRNPA 1310 Query: 849 LRPRHWEAMSAIVGYPL-QPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEK 907 LR RHW+ + + Q S+ T+ +++ ++ ++++ IS +A+KE ++E A++ Sbjct: 1311 LRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQN 1370 Query: 908 MITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWE 967 + WD + I Y++ G L +E+ L+D+ + TM+ S F+K +EK + WE Sbjct: 1371 IAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWE 1430 Query: 968 GKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027 L L+ E+++ L VQ W+YLE IF DI Q+P E F V+ W+ IM + +D Sbjct: 1431 RCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKD 1490 Query: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087 + L +L+ L + N +LE I K L+ YLE KR FPRF+FLSND+LLEIL +++ Sbjct: 1491 NNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSR 1550 Query: 1088 DPTRVQPHLKKCFEGIAKVEFTET------LDITHMKSSEGEVVELIEIISTAKARGQVE 1141 +P VQPHLKKCF+ I + + + M S +GE ++ + + G VE Sbjct: 1551 NPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFL---EGPVE 1607 Query: 1142 KWLVELERVMINSIHKVTGDATFAYTKY--ERINWVRDWPGQTVLCVSQIFWTKEV-QTA 1198 WL ++E+ M ++ + + A K+ +R WV++W GQ V+ SQI WT +V + Sbjct: 1608 SWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCL 1667 Query: 1199 IPMGIKALEQYLKTCNRQIDDIVT----LVRGKLSMQNRVTLGALVVLDVHARDVLSSLV 1254 + +A ++ LK + I+ +RG L+ R+ + ALV +++HARDVL L Sbjct: 1668 LTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLY 1727 Query: 1255 KKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYR 1312 K + D + F+WLSQLR+YW+++ + N +Y YEYLGNS RLVITPLTDRCY Sbjct: 1728 KSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYM 1787 Query: 1313 TLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLS 1372 TL ALHLH GG+P+GPAGTGKTET KDL KA+ +V NCS+GLDY ++G+ + GL Sbjct: 1788 TLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQ 1847 Query: 1373 CGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNP 1432 GAW CFDEFNRI++EVLSVVA QIL I + AG F+G E+ L +C +FITMNP Sbjct: 1848 TGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNP 1907 Query: 1433 GYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQL 1492 GYAGR+ELP+NLK++FR +AM+VPD +IAEI+L+ GF + L+ K+ Y L +QL Sbjct: 1908 GYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQL 1967 Query: 1493 SSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGIT 1552 S Q HYD+G+RA+ S+L AG + P+ +E +LL S+ D+N+ K S D PLF I Sbjct: 1968 SRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIV 2027 Query: 1553 SDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPF 1612 DLFP ++LP DY L ++ M LQ T F K+ Q+YE RH MIVG Sbjct: 2028 QDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTG 2087 Query: 1613 GGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLA 1672 GKT+++R+L +L+ +C G N V+ LNPK++++G+LYG++D ++EW+DG+L+ Sbjct: 2088 SGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILS 2147 Query: 1673 VSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFE 1732 R + PD KW++FDGPVD +WIENMN+V+DDNK L L++GE I M Q++L+FE Sbjct: 2148 SVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFE 2207 Query: 1733 PMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLP-ASVSVIQKEFIMGLFDRMVP 1791 DL +ASPATVSRCGM+Y + LGW+P + SW+ P A V +Q+ +F++++ Sbjct: 2208 VEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQR-----MFEKLIN 2262 Query: 1792 VSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLF 1851 + F + + KEL P + + + SL L E + + +++E F+F Sbjct: 2263 KMLAFKKDNCKELVPLPEYSGITSLCKLYSALA---TPENGVNPADGENYVTMVEMTFVF 2319 Query: 1852 SLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKG 1911 S+IWSV AS ++ R + + LRE+ S FP K Sbjct: 2320 SMIWSVCASVDEEGRKRIDSYLREIEGS---------------------------FPNKD 2352 Query: 1912 TIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKP 1971 T+Y+Y FV I W + KL ++ P + F +I+VPT+DT+RY+ L+ L +Q P Sbjct: 2353 TVYEY-FVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNP 2411 Query: 1972 SIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVF 2031 + VGP GTGK+ I +L L + L++N SAQTT+ Q+I+ S+++KR KGV+ Sbjct: 2412 ILLVGPVGTGKT-SIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVY 2470 Query: 2032 GPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCA 2091 P GK M+ F+DD+NMPA++++G+QPP+EL+R W+D+ WYD ++ + ++ +M A Sbjct: 2471 VPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAA 2530 Query: 2092 MGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQ 2151 MGPPGGGR ++PR FNII + + + IF ++ L+ F +E + Sbjct: 2531 MGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQ---DFEEEVKPIGNV 2587 Query: 2152 IVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHE 2211 + T+ +Y ++ LPTP K HYLFNLRD S+V QG+ + + +T I RLW+HE Sbjct: 2588 VTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHE 2647 Query: 2212 VLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFC 2271 RV+ DRL+D D + I + L ++ FH L R +F Sbjct: 2648 CFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHL-------------CPSKRPPIFG 2694 Query: 2272 DFHDPKREDTNYREIADVDNLRMIVEIHLEEYN-NISKKPMNLVLFRFAIEHISRISRIL 2330 DF +E Y ++ D+ L+ ++E L EYN + S PM LVLFR AIEHI+RI R++ Sbjct: 2695 DF---LKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVI 2751 Query: 2331 KQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEG 2390 QPR + LLVG+GGSGRQS+ RLA+ + DY+ FQ+E++K Y E+ +D+K + R+ Sbjct: 2752 GQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVE 2811 Query: 2391 EMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQT 2450 F+F DTQI +ESFLED++N+L++GE+PNL+ DE +EI + +D+ R +Q Sbjct: 2812 LKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEI--QSHIIDQAR--VEQV 2867 Query: 2451 DGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQ 2510 S +LF I+ ++ LH+VL +SP+GD FRN +R++PALVNC TI+WF WP++AL Sbjct: 2868 PESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALL 2927 Query: 2511 AVASRFLEEIEM--SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELIS 2568 VA + L +++ E I + + H S S+ +EL+R+NYVTPT YLEL+S Sbjct: 2928 EVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLS 2987 Query: 2569 TFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMI 2628 +K LL +KR E++ + GL K+D +V M +ELE ++ K+ +E ++ Sbjct: 2988 GYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLV 3047 Query: 2629 MIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTA 2688 +I ++ E + +K V A+ + + +A+ D DL ALP LE A+ AL++L Sbjct: 3048 IIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNK 3107 Query: 2689 QDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRF 2748 +DI +KS PPA V++VM+A+ IL+G +PT W AKR LG+ F Sbjct: 3108 KDIGEIKSYGRPPAQVEIVMQAVMILRG------NEPT---------WAEAKRQLGEQNF 3152 Query: 2749 LQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAK 2808 ++SL +DKDNI + I Y PDF P+ I S AA+ LC WV AM+ Y ++ + Sbjct: 3153 IKSLINFDKDNISDKVLKKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYR 3211 Query: 2809 IVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ-------KKAD 2861 +V PK+I++ AA + LR+KQAAL E Q+KL + + LE+ K+ +K + Sbjct: 3212 VVEPKRIRMNAALAQ-------LREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEE 3264 Query: 2862 LENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAF 2921 L + + KLERA L+ GL GEK RW T L + L GD L+++ ++Y+G F Sbjct: 3265 LRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPF 3324 Query: 2922 TSTYRQNQTKE-WTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGII 2980 + YR + W +PCS ++ L +R WNI GLPSD+FS +NGII Sbjct: 3325 LTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGII 3384 Query: 2981 IMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVG 3040 + RW LMIDPQ+QA KWIKNME L +I L DY+R LE+ I FG PVLL+NV Sbjct: 3385 VTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQ 3444 Query: 3041 EELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTL 3100 E LDP L P+L K + GG +R+GD +EY +FRFYITTKL NPHY PETS K T+ Sbjct: 3445 EYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTI 3504 Query: 3101 LNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEG 3160 +NF + +G++ QLLGIVV +ERP+LEE+K +L++ A KR+LKE+ED+IL +L+ + G Sbjct: 3505 VNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATG 3564 Query: 3161 NILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADL 3220 ++L+D + L +SK A E++++ E +E TE D R YRP A +SILFF L D+ Sbjct: 3565 SLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDM 3624 Query: 3221 ANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKL 3280 I+PMYQ+SL +I+LFILSI+ S +S L R+ L D+ TY++Y CR+LFE+ KL Sbjct: 3625 GCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKL 3684 Query: 3281 LFSFCLTINLLLHERAINKAEWRFLLTGGIGLD--NPYANLC-TWLPQKSWDEICRLDDL 3337 LFSF + +L +N E+ F L GG+ LD N C +WL WD I LD L Sbjct: 3685 LFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKL 3744 Query: 3338 PAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPML 3397 F + F + W Y + P + P EWE+ NE QRMLI+R LR D+V + Sbjct: 3745 TNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCV 3804 Query: 3398 QEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSK 3457 FII LG FIEPP ++ DS +PL+F+LSPG DP +ALL+ A+ G + Sbjct: 3805 TSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM-AQR 3863 Query: 3458 LSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFR 3517 +LSLGQGQ PIA ++L + V +G WV L NCHL+ SWMP L+K+ E+L E HP FR Sbjct: 3864 FHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFR 3923 Query: 3518 MWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKK 3577 +WL+S P P+FP+S+LQ +KMT E PKGL+AN+ R Y + +S+P+ F C KP ++KK Sbjct: 3924 LWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQL--MSEPQ-FSRCSKPAKYKK 3980 Query: 3578 LLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMT 3637 LL+ LCFFH+++ ER+KF LGWNI Y FN++D +S L ++L++YEE P++AL+Y+ Sbjct: 3981 LLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLI 4040 Query: 3638 GECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTK 3697 NYGG VTDDWDRR L + +N +F + + ++ + YF+P G SY EY Sbjct: 4041 AGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYIS 4100 Query: 3698 TLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDEVVNEVASD 3755 LP PE FG + NAD+ +E Q LFD +L Q + AG ++ +E V E+A+D Sbjct: 4101 LLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAAD 4160 Query: 3756 ILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAV 3815 + K+P D E + +N VL+QE+ R+N L++TI S +++K I+GL V Sbjct: 4161 VKQKIPEMIDYEGTQKLLALD-PSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIV 4219 Query: 3816 MSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFW 3874 MST LEE+ + I + +P +W GK+YPS KPL ++ D R++ + W PP +FW Sbjct: 4220 MSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFW 4278 Query: 3875 LSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEV--MEDKEYKHPPEDGVFIHGLFLDG 3932 LSGF F FLT Q+ AR+ + +D L +++ V ++D +PP+DGV++ GL+L+G Sbjct: 4279 LSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEG 4338 Query: 3933 ASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGH 3992 A W+RK L E+ P L +P + +P + + Y P Y R G + Sbjct: 4339 AGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSD 4394 Query: 3993 STNFVIAMTLPSD-QPKEHWIGRGVALLCQLNS 4024 +FVI + L S +HWI RG ALL L+S Sbjct: 4395 RASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS 4427 >gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] Length = 3092 Score = 2092 bits (5421), Expect = 0.0 Identities = 1096/2238 (48%), Positives = 1484/2238 (66%), Gaps = 57/2238 (2%) Query: 165 YYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDS---IVTLSDEMREDYLLSVRKS 221 Y Y+ +++ + P++ WL+H+L L+P+ LK + + +L +E+ D+ S+++ Sbjct: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155 Query: 222 IVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAV 281 +V VL P K + + LP ++ PW S++ A + I +L+ ++PTM + Sbjct: 156 LVQSVLVKPPVKSLEDEGGPLPESPVGLDY-SNPWHSSYVQARNQIFSNLHIIHPTMKML 214 Query: 282 LDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQ 341 LDL +T F L+D + ++ S + + +A+E ++ W+P+V N++ Sbjct: 215 LDLGYTTFADTVLLDFTGIR-AKGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF-- 271 Query: 342 GNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPG 401 KK+ G KL++F++C + LM+ QL+DL +++ F L P D R P Sbjct: 272 --TKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-DPKDQQRL---PI 325 Query: 402 FIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLK 461 F + L D+D ++F P D D L++ + + +A+ V + + L + T L Sbjct: 326 FKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELP 385 Query: 462 PIILNEIVDAHKEKIKEVIMKESVAPTEHLRLY-DKYDFLITRKAERDVDNFLAENHSYE 520 +L+ VD +K + + +H Y +KY++L+ A +++ F E+H+++ Sbjct: 386 EHVLHWAVDT----LKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFD 441 Query: 521 KIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQ 580 + + I K+ L EI + I M + CE+L L +A LL + ++ Sbjct: 442 EYTEFIEKFLSLASEIMLLP-QWIHYTMVRLDCEDLKTGLTNKAKAFANILLNDIASKYR 500 Query: 581 EVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLI 640 + N +C EFE I E AL P T E+M++ +Y++K + EL R+ +SK +++ + Sbjct: 501 KENECICSEFEAIKEHALKVPETTEEMMDLISYVEKARTVGIEELILRIQESKRQMSYFL 560 Query: 641 EYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYA 700 + F D+ LN +V W ++ IF+E+ ++I+ + + L + E+ + E+E + Sbjct: 561 DVFLFPQEDLALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKES 620 Query: 701 KQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQ 760 ++ EEF F +L+ +Q+Y+ + L ++ + + ++ N EEE F W + YP+ K++ Sbjct: 621 RRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLK 680 Query: 761 DGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYK--------LEK 812 + PY + + +++ + + W +G + +N + +EAD+ + R ++K L+K Sbjct: 681 VNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKK 740 Query: 813 TFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDST 872 + A K+E+ + I +C +R RHW+ +S IVGY L P +T Sbjct: 741 ELQEKRKAARKRSLEEEKIEEEPKDNATI-TMCR--MRARHWKQISEIVGYDLTPDSGTT 797 Query: 873 VSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILAS 932 + L +NL PY+++FE IS ASKE+SLEKAM MI W+ + F I YR+TG IL+S Sbjct: 798 LRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSS 857 Query: 933 VDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEP 992 VDEIQ +LDD IIKTQTMRGSPFIKP+E +++ WE +L+ +QE +DEWLKVQA WLYLEP Sbjct: 858 VDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEP 917 Query: 993 IFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLEL 1052 IF S DIM QMPEEGR+F VD+ WRDIM+ +D VL ++ +LE+L+ NELLE Sbjct: 918 IFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEK 977 Query: 1053 ILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETL 1112 I+KGLN YLEKKRLFFPRFFFLSNDE+LEILSETKDP RVQPHLKKCFEGIAK+EF L Sbjct: 978 IMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNL 1037 Query: 1113 DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERI 1172 DI M SSEGE VELI +IST+ ARG VEKWL+++E +M+ S+H V A AY + R Sbjct: 1038 DIKAMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARR 1097 Query: 1173 NWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQN 1232 +WVR+WPGQ VLC+SQ+FWT E Q I G + L++Y K Q+++IV LVRGKLS Q Sbjct: 1098 DWVREWPGQVVLCISQMFWTSETQEVISGGTEGLKKYYKELQNQLNEIVELVRGKLSKQT 1157 Query: 1233 RVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETKMINAGLRYGY 1292 R TLGALV +DVHARDV+ ++K +S D+DF WL+QLRYYW+ + ++IN ++Y Y Sbjct: 1158 RTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIINCNVKYAY 1217 Query: 1293 EYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVF 1352 EYLGNSPRLVITPLTDRCYRTL GA +L+LGGAPEGPAGTGKTETTKDLAKA+A QCVVF Sbjct: 1218 EYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVF 1277 Query: 1353 NCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILM 1412 NCSDGLDYLA+GKFFKGL S GAWACFDEFNRI+LEVLSVVAQQIL IQR I + + Sbjct: 1278 NCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFV 1337 Query: 1413 FEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFV 1472 FEGTELKL+P C V ITMNPGYAGRSELPDNLK LFRTVAMMVP+YA+IAEI LYS GF+ Sbjct: 1338 FEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFL 1397 Query: 1473 TARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSI 1532 ARPLSVKIV TYRLCSEQLSSQ HYDYGMRAVK+VL AAGNLKLKYPNENE+ILLLRSI Sbjct: 1398 NARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSI 1457 Query: 1533 IDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKI 1592 DVN PKFLSHD+PLF GITSDLFPG+KLP+ DY++ L + C NLQ FF EKI Sbjct: 1458 KDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKI 1517 Query: 1593 LQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTM 1652 +Q YEMMIVRHGFM+VGEPF KT VLA L + E G EE KV +NPKS+TM Sbjct: 1518 IQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITM 1577 Query: 1653 GQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKK 1712 GQL+GQFD VSHEW+DG++A +FR FA S TPDRKW++FDGP+D +WIE+MNTVLDDNKK Sbjct: 1578 GQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKK 1637 Query: 1713 LCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPA 1772 LCLMSGEIIQMSPQM+LIFE MDL ASPATVSRCGMIY+EP LGW PL+ SW+N L Sbjct: 1638 LCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKG 1697 Query: 1773 SVSVIQKEFIM-GLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEV 1831 + + + ++ GLF ++P S+ R +L+ T + + L LI + ++ V Sbjct: 1698 PLCEPEYQALLRGLFAWLIPPSLN-QRVELFQLNYLYTTIVSKILKILITFRISNYFKYV 1756 Query: 1832 KLKERNDRETYSL-LEGIFLFSLIWSVGASCTDDDRLKFNKILRELM-----ESPISDRT 1885 LK + + L + F+FSLIWS+G SC D R F+ +R ++ E+P+ D Sbjct: 1757 PLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPD-- 1814 Query: 1886 RNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMF 1945 S PF EKG +YDY + + G+W W + +K K + Sbjct: 1815 -------------SVGKWECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKI 1861 Query: 1946 NEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLIN 2005 +IIVPT+DTIRY+ LM+L T+ KP +FVGPTGTGKSVY+ + L+N L K+ Y P IN Sbjct: 1862 QDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYIN 1921 Query: 2006 FSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQ 2065 SA+T+A Q QNI+M++LDKRRKGVFGPP+GK+ ++F+DD+NMPA E YGAQPPIELLRQ Sbjct: 1922 LSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQ 1981 Query: 2066 WLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYT 2125 + D +WYDLKD S I LVDI+++ AMGPPGGGRNPVTPR +RHFNI +IN FSD++M Sbjct: 1982 FFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVR 2041 Query: 2126 IFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSR 2185 IFS I+ ++L ++FP E+ + QIVNGTM +YK++++NLLPTP KSHY FNLRDFSR Sbjct: 2042 IFSSIVAFYLR-THEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSR 2100 Query: 2186 VIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDF 2245 VI+G L + + RL+VHEVLRV+YDRL+++ DR WL + +++++ E F Sbjct: 2101 VIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESF 2160 Query: 2246 HELFQRLDFDNDGMVEADDLRSLMFCDFHDPKRE--DTNYREIADVDNLRMIVEIHLEEY 2303 H +F L N + E +DLR+LMF D+ +P E D Y EI ++ + +V+ L+EY Sbjct: 2161 HSIFSHLRKQNAPVTE-EDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEY 2219 Query: 2304 NNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVF 2363 N K MNLV+FR+ +EH+SRI R+LKQ +ALLVG+GGSGRQS+TRLA MA +F Sbjct: 2220 NQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIF 2279 Query: 2364 QVEISKGYDTTEWHEDLK 2381 Q EISK Y EW ED+K Sbjct: 2280 QPEISKSYGMNEWREDMK 2297 Score = 1006 bits (2602), Expect = 0.0 Identities = 472/780 (60%), Positives = 603/780 (77%), Gaps = 3/780 (0%) Query: 3247 KSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLL 3306 KS+IL KRL+ L DHFTY+LY N+CRSLFEKDKLLFSF L NLLL + I E FLL Sbjct: 2312 KSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLL 2371 Query: 3307 TGGIGLDNPYANLC-TWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHH 3365 TGG+ L + N TWL KSW+EICR + PAF+ +R+ F W+++YDS EPH+ Sbjct: 2372 TGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHN 2431 Query: 3366 EVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSN 3425 FP + NE Q+++I+RCLRPDK+ P + ++ ++LG+ F+EPPPFDL K++ DSN Sbjct: 2432 AKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSN 2491 Query: 3426 CCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWV 3485 C PLIFVLSPGADPMA+LLKFA+D+ G+K ++SLGQGQGPIA KM++ A++EGTWV Sbjct: 2492 CTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWV 2551 Query: 3486 VLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPK 3545 LQNCHLA SWMP LEK+CE+ + E+ + FR+WLTSYPS FPV++LQNGVKMTNE P Sbjct: 2552 CLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPT 2611 Query: 3546 GLRANIIRSYLMDPISDPEFFGSCKKPE-EFKKLLYGLCFFHALVQERRKFGPLGWNIPY 3604 GLR N+++SYL DP+SDPEFF C+ E ++KLL+G+CFFHALVQER+KFGPLGWNIPY Sbjct: 2612 GLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPY 2671 Query: 3605 EFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFN 3664 FNE+DLRIS++QL +F+N+Y+ +P+EA+ Y+TGECNYGGRVTDDWDRR L ++L F+N Sbjct: 2672 GFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYN 2731 Query: 3665 PELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQ 3724 +VEN YKF SG YF PP G ++ YIE+ K LP T PEIFG++ N DI+KD +T+ Sbjct: 2732 LYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTK 2791 Query: 3725 LLFDNILLTQSRSAGAGAK-SSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNT 3783 LF+++LLTQ S GA S+D+++ E+ DIL KLP++FDIE A+R+YP Y +SMNT Sbjct: 2792 TLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMNT 2851 Query: 3784 VLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPS 3843 VLVQEM RFN L+ TIR++ +++KAIKG+ VM + LE + S+L K+PE+W +SYPS Sbjct: 2852 VLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPS 2911 Query: 3844 LKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLL 3903 LKPLGSY+ DFLARL FLQ WY G P VFWLSGFFFTQAFLTGA QNYARKYT PIDLL Sbjct: 2912 LKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLL 2971 Query: 3904 GFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCK 3963 G+++EV+ PEDGV+IHGL+LDGA W+R+ LAE +PK+L+D +P++W+KP + Sbjct: 2972 GYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQ 3031 Query: 3964 RADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLN 4023 ++ I K +YV PLYKTSER+G LSTTGHSTNFVIAM L +DQP HWI RGVALLCQL+ Sbjct: 3032 KSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLD 3091 >gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] Length = 4471 Score = 2056 bits (5328), Expect = 0.0 Identities = 1239/3557 (34%), Positives = 1961/3557 (55%), Gaps = 175/3557 (4%) Query: 519 YEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRD 578 Y KI E+ ++ + +E IRL + H ++ K I GKLL + ++ Sbjct: 1028 YSKIAYEVMRHPLIKDE------HCIRLQL--RHLANTVQENAKSWVISLGKLLNESAKE 1079 Query: 579 HQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAF 638 L +E E +A+ P +L + A I ++ ++ +E R D + Sbjct: 1080 ELY---NLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLV-MELRYRDVQERYRT 1135 Query: 639 LIEYVNFSP-ADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELE 697 + Y F P A+ L + + + + + + + E + + ++E Sbjct: 1136 MAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIE 1195 Query: 698 SYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQ 755 +AK+ SE S GD D+ + ++ + +L ++ E+ F ++YP+ Sbjct: 1196 EFAKRFYSEGPGSVGD--DLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPE 1253 Query: 756 RKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFH 815 K+Q ++ +YE W++ + +N ++ I + R L KL + Sbjct: 1254 LLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVR 1313 Query: 816 DSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSS 875 L++T + +K++ FK IPL+ + N LR RHW+ + + ++ T+ + Sbjct: 1314 ----GLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLEN 1369 Query: 876 FLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSY----RETGTFILA 931 M L + D I AA KE ++EKA+++++ W+ ++F + Y +E G +IL Sbjct: 1370 MFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERG-YILG 1428 Query: 932 SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLE 991 SVDEI LDD+ Q++ GS F+ P+ + + +WE L L+ E+++ W+ VQ W+YLE Sbjct: 1429 SVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLE 1488 Query: 992 PIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLE 1051 IF DI SQ+PEE ++F +DK ++ IM ++D + L L+ +E LE Sbjct: 1489 SIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLE 1548 Query: 1052 LILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET 1111 K LN+YL+ KR FPRFFF+S+DELL IL + DP VQ H+ K ++ IA + F + Sbjct: 1549 KCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMYDNIASLRFNDG 1607 Query: 1112 LD----ITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYT 1167 ++ M S+EGEV+E +I+ +A G+VE W+ + M + +T +A F Y Sbjct: 1608 DSGEKLVSAMISAEGEVMEFRKIL---RAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYC 1664 Query: 1168 K-YERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK----ALEQYLKTCNRQIDDIVT 1222 + R++W+ + G VL SQ++WT EV+ K A++ Y + +RQID++VT Sbjct: 1665 EDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVT 1724 Query: 1223 LVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW--QENHLE 1280 + LS +R ++++DVHARD++ S ++ +I + +F+W SQLR+YW + + L Sbjct: 1725 RITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELN 1784 Query: 1281 TKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKD 1340 + YGYEY+G + RLVITPLTDR Y TL AL ++LGGAP GPAGTGKTETTKD Sbjct: 1785 IRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKD 1844 Query: 1341 LAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTI 1400 LAKA+ CVV NC +G+DY A+GK F GL CGAW CFDEFNRID VLSV++ QI TI Sbjct: 1845 LAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTI 1904 Query: 1401 QRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAM 1460 + + FEG E+ LD +FITMNPGYAGR+ELP+++KALFR V ++VPD Sbjct: 1905 RNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQ 1964 Query: 1461 IAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYP 1520 I EI+L+S GF+ A+ L+ K+ Y+L EQLS Q+HYD+G+RA+KSVL AG LK Sbjct: 1965 ICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSS 2024 Query: 1521 NENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPK---PDYNDLLAAI--KD 1575 + E+++L+R++ D+NLPKF+ D+PLF G+ SDLFPG+ P+ PD+ND + + ++ Sbjct: 2025 DLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEEN 2084 Query: 1576 NCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLM 1635 A + +Q+ +K++Q++E M+ RH M+VG GGK+ +N +C+ Sbjct: 2085 GYAVLPIQV-----DKVVQMFETMLTRHTTMVVGPTRGGKSV-------VINTLCQAQTK 2132 Query: 1636 EENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSV-TPDRKWLIFDGP 1694 ++ +LNPK+V++ +LYG D + +W+DGVL+ FR +RK+++FDG Sbjct: 2133 LGLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGD 2192 Query: 1695 VDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEP 1754 VDA+W+ENMN+V+DDN+ L L +GE I++ L+FE DL+ ASPATVSRCGM+Y++P Sbjct: 2193 VDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDP 2252 Query: 1755 HMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFI---------RKHTKELS 1805 L +RP WVN +P + +++ + LF++ VP ++ I + K + Sbjct: 2253 KNLKYRPYWKKWVNQIP---NKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIV 2309 Query: 1806 PTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDD 1865 P +D N+V L ++D ++ + E LLE FL +L S+GAS +D Sbjct: 2310 PQTDLNMVTQLAKMLDALLE-----------GEIEDLDLLECYFLEALYCSLGASLLEDG 2358 Query: 1866 RLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGK 1925 R+KF++ ++ L D TE + +P + T+YD+ F + + Sbjct: 2359 RMKFDEYIKRLASLSTVD-----------TEGVWANPGELP-GQLPTLYDFHFDNKR-NQ 2405 Query: 1926 WEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVY 1985 W PW K + E P+ N I+V T+DT R + ++E + ++P IFVG +GT K+ Sbjct: 2406 WVPWSKLVPEYIHAPERKFIN-ILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTAT 2464 Query: 1986 ITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDD 2045 NFL N L++E L++NFS++TT+ Q + + ++KR K +GPP+GKR++VF+DD Sbjct: 2465 TQNFLKN-LSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDD 2523 Query: 2046 VNMPAREVYGAQPPIELLRQWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTP 2104 +NMP + YG Q PI LL+ L+ YD K+ + + D+ + AMG GGGRN V P Sbjct: 2524 MNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDP 2583 Query: 2105 RYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAM 2164 R++ F++ + S++S++ I+S IL H F + + ++ ++ T+ LYK + Sbjct: 2584 RFISLFSVFNVPFPSEESLHLIYSSILKGHTS---TFHESIVAVSGKLTFCTLALYKNIV 2640 Query: 2165 KNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNT 2224 ++L PTP+K HY+FNLRD SRV G+ L+ PE +T + R+W +E LRV++DRL+ T Sbjct: 2641 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 2700 Query: 2225 DRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDP--KREDTN 2282 D+ + +I ++ + +D VE ++F DF + E Sbjct: 2701 DKQLVQQHIGSLVVEHFKDD---------------VEVVMRDPILFGDFQMALHEGEPRI 2745 Query: 2283 YREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGV 2342 Y +I D + + + + LEEYN + K MNLVLF A+EH++R+ RI++ R HALLVGV Sbjct: 2746 YEDIQDYEAAKALFQEILEEYNESNTK-MNLVLFDDALEHLTRVHRIIRMDRGHALLVGV 2804 Query: 2343 GGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQ 2402 GGSG+QS++RLAA A VF++ +S+GY + EDLK + K +FLFTD Sbjct: 2805 GGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAH 2864 Query: 2403 IKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDG-SPIALFNMF 2461 + EE FLE ++N+L +G +P LF+ +EK+ I ++ Q + KQ G + +++ F Sbjct: 2865 VAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQ-----EALKQGMGPAKESVWQYF 2919 Query: 2462 IDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIE 2521 ++ + LH+VL MSP+GD R R FP +VN IDWF WP AL AVA FL Sbjct: 2920 VNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNP 2979 Query: 2522 M-SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE 2580 M E + + H S S+ F +L+R NYVTP +YL+ I+T+ LL++K Sbjct: 2980 MIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQC 3039 Query: 2581 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT 2640 + KR + GL+KL A+ Q+ + +L Q V +++ ++E+ +V A Sbjct: 3040 NIAQCKRLDGGLDKLKEATIQLDELNQKLA---EQKIVLAEKSAACEALLEEIAVNTAVA 3096 Query: 2641 EKIVKADETIANEQAMASKAI---KDECDADLAGALPILESALAALDTLTAQDITVVKSM 2697 E+ K E A E +K I K E + LA +PILE+A L L D+T ++S Sbjct: 3097 EEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSF 3156 Query: 2698 KSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDK 2757 PP V+ V E I I+KG K E W AK ++ D FL+SL E D Sbjct: 3157 AKPPKQVQTVCECILIMKGYK--------------ELNWKTAKGVMSDPNFLRSLMEIDF 3202 Query: 2758 DNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKL 2817 D+I + + I K + + E++ S A G+ K+V A+ Y V + + PK+ K+ Sbjct: 3203 DSITQSQVKNI-KGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKV 3261 Query: 2818 AAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAE 2877 A E + L + Q L +Q +L L E +K L+ + ++ ++L A+ Sbjct: 3262 ARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAAD 3321 Query: 2878 QLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKE-WTTL 2936 +LI GLG E RW + EL + L GD L+ + ++Y GAFT +R W Sbjct: 3322 KLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQND 3381 Query: 2937 CKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQ 2996 R+IP S L L + V I W GLP D S+ NGI+ A R+PL IDPQ Q Sbjct: 3382 ILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQ 3441 Query: 2997 ANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTF 3056 A WIK E+ N+L V ++PD+++ LE I++GTP L +V E +DP+++ +L K Sbjct: 3442 ALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIK 3501 Query: 3057 KQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLG 3116 G I LGD ++Y +FR Y+ TKL NP Y P K ++N+ +T +G++DQLL Sbjct: 3502 VSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLS 3561 Query: 3117 IVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSK 3176 ++VA ER +LEE+++ LI + +ENK LK++ED +L L++S GN+L++ + L +K Sbjct: 3562 VLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETK 3621 Query: 3177 ALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFIN 3236 + A E+S+K ++AE+T ID R GYRP A +ILFF L+++A + MYQYSL F+ Sbjct: 3622 SKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLE 3681 Query: 3237 LFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERA 3296 +F LS++ S IL KRL+ + D T+S+Y + C LFE+ KLLFSF +TI + E Sbjct: 3682 VFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGR 3741 Query: 3297 INKAEWRFLLTGGIGLD-NPYANLCTWLPQKSWDEICRLDDL--PAFKTIRREFMRLKDG 3353 + + E F L G I L+ + C WL + W++I L ++ F + + + Sbjct: 3742 VPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTV 3801 Query: 3354 WKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPP 3413 W++ YD P +++ FQ++LI+RC R D+V + +++ +G +++PP Sbjct: 3802 WQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPP 3861 Query: 3414 PFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMK 3473 F S +P++F+LSPG+DP L+K A+ G+GG++L L++GQGQ +A++ Sbjct: 3862 MISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQ 3921 Query: 3474 MLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVL 3533 +LE AV G W++LQNCHL W+ LEK E ++ HPDFR+WLT+ P+ FP+ +L Sbjct: 3922 LLETAVARGQWLMLQNCHLLVKWLKDLEKSLERIT--KPHPDFRLWLTTDPTKGFPIGIL 3979 Query: 3534 QNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERR 3593 Q +K+ E P GL+ N+ +Y E C P FK L+Y L FFHA+VQERR Sbjct: 3980 QKSLKVVTEPPNGLKLNMRATYFK---ISHEMLDQCPHP-AFKPLVYVLAFFHAVVQERR 4035 Query: 3594 KFGPLGWNIPYEFNETDLRISVQQLHMFLNQY-----EELPYEALRYMTGECNYGGRVTD 3648 KFG +GWN+ Y+FNE+D ++ ++ L+ +L + +P+ +L+Y+ GE YGGR D Sbjct: 4036 KFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAID 4095 Query: 3649 DWDRRTLRSILNKFFNPELVENSD--YKFDSSGIYFVPPSGDHK-SYIEYTKTLPLTPAP 3705 +DRR L ++++ + + + F + + + P GD K ++E + LPL P Sbjct: 4096 SFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTP 4155 Query: 3706 EIFGMNANADITKDQSETQLLFDNILLTQSRSA-GAGAKSSDEVVNEVASDILGKLPNNF 3764 E+FG++ NA+I + ++ ++L Q ++ + S D+ + +VA +I K+P F Sbjct: 4156 EVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVF 4215 Query: 3765 DIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVV 3824 D++ +R T + + + VL+QE+ RFNKL+ + S +Q+A+ G MS +L++V Sbjct: 4216 DLDQVRKRLGTGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVA 4274 Query: 3825 SSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAF 3884 S+ IP +W + +LK LG+++ FL R W P V WLSG +++ Sbjct: 4275 RSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESY 4334 Query: 3885 LTGAQQNYARKYTIPIDLLGFDYEV---MEDKEYKHPPEDGVFIHGLFLDGASWNRKIKK 3941 LT Q RK P+D +V + E G F+ GL+L+GA W+ + Sbjct: 4335 LTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGC 4394 Query: 3942 LAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMT 4001 L +S PK+L +P++ + P + + + ++ P+Y TS RR + V Sbjct: 4395 LIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEAD 4449 Query: 4002 LPSDQPKEHWIGRGVAL 4018 L + + HW+ +GV L Sbjct: 4450 LFTTRHISHWVLQGVCL 4466 >gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo sapiens] Length = 4470 Score = 1980 bits (5129), Expect = 0.0 Identities = 1223/3695 (33%), Positives = 1948/3695 (52%), Gaps = 202/3695 (5%) Query: 400 PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458 P F +R+ LD D + F P L D FL + + ++ + V R+ +L +K + Sbjct: 906 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 960 Query: 459 TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513 + N + +E++ +++ E+ +++Y +L T + + NFL Sbjct: 961 YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1020 Query: 514 --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558 AE+ + + ++I Y+KL EE+ + G + C + Sbjct: 1021 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1080 Query: 559 ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611 AL+ + MF+ H V L D F ++A L+ P + L+E+ Sbjct: 1081 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1135 Query: 612 AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671 ++ KV+ + K + L Y P ++ L + + Sbjct: 1136 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1194 Query: 672 KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGD---LQDVQRYLKKAQIL 725 K+ ++ + L+ +C++F + + ++ E +SF D + + + K + Sbjct: 1195 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAM 1254 Query: 726 NGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTE 785 G ++ + F + L + + + + +++ L++ V +++ W Sbjct: 1255 EGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKT 1307 Query: 786 GPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVIC 845 + +N +Q++ D + + + L+K + + V++ + + + + Sbjct: 1308 TKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQ 1363 Query: 846 NPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAM 905 NP +R RHW+ + + S+++T++ L +NL Y D I + A KE +EK + Sbjct: 1364 NPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVL 1423 Query: 906 EKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMRE 965 + + + W +EF + TGT +L S + + L+D+ ++ Q + S ++ + K++ Sbjct: 1424 KALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTS 1483 Query: 966 WEGKLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSV 1024 W+ KL ++ W +VQ TW +LE IF S DI +Q+P + +RF +++ ++ +M Sbjct: 1484 WQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDA 1543 Query: 1025 MQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILS 1084 ++ +V+ + + +L+ + L + K L EYLE KRL FPRF+F+S+ +LL+ILS Sbjct: 1544 VKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILS 1603 Query: 1085 ETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVE 1141 DP V HL K F+ + K++F +K G + E + GQVE Sbjct: 1604 NGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVE 1663 Query: 1142 KWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPM 1201 WL + M +++ +A Y + R W+ D+P Q L +QI+WT EV A Sbjct: 1664 VWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFAR 1723 Query: 1202 GIKALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKN 1257 + E ++ N+ Q++ ++TL+ G L+ +R+ + + +DVHARDV++ ++ Sbjct: 1724 LEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAK 1783 Query: 1258 ISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLF 1315 + F W +QLR+ W E H + +A ++Y YEYLGN+PRLVITPLTDRCY TL Sbjct: 1784 VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLT 1843 Query: 1316 GALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGA 1375 +LHL +GGAP GPAGTGKTETTKDL +A+ VFNCS+ +DY + G +KGL GA Sbjct: 1844 QSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGA 1903 Query: 1376 WACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYA 1435 W CFDEFNRI +EVLSV+A Q+ +Q I A F G + L PT +FITMNPGYA Sbjct: 1904 WGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYA 1963 Query: 1436 GRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQ 1495 GR+ELP+NLKALFR AM+VPD+ +I EI+L + GF+ AR L+ K + Y LC E LS Q Sbjct: 1964 GRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQ 2023 Query: 1496 HHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDL 1555 HYD+G+RA+KSVL AG+LK P+ E+ +L+R++ D N+PK ++ DLP+F G+ DL Sbjct: 2024 DHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDL 2083 Query: 1556 FPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGK 1615 FP + +P+ + IK + + LQ F K++Q+ E++ VRH IVG GK Sbjct: 2084 FPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGK 2143 Query: 1616 TSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSF 1675 + + L ++ K + + L+PK+VT +L+G + V+ EW DG+ + Sbjct: 2144 SQVLKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIM 2196 Query: 1676 RAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMD 1735 R A+ KW+I DG +D +WIE++NTV+DDNK L L S E I ++ M L+FE Sbjct: 2197 RDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISH 2256 Query: 1736 LEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVE 1795 L A+PATVSR G++Y+ P LGW P++ SW+ +K +M LFD+ +P ++ Sbjct: 2257 LRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLD 2313 Query: 1796 FIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIW 1855 +R K+++P + ++++++ L++C + E + + RE Y L F+F+ W Sbjct: 2314 KLRFGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFW 2366 Query: 1856 SVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYD 1915 + G + D + + S N FK T+ FP +GTI+D Sbjct: 2367 AFGGAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFD 2405 Query: 1916 YQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFV 1975 Y ++ K+ PW K+ P DV +V T +TIR M+LL P + V Sbjct: 2406 Y-YIDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLV 2463 Query: 1976 GPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPL 2035 G GTGKSV + + L LN + Y + F+ TT+A Q ++ L+K+ +GPP Sbjct: 2464 GNAGTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPG 2522 Query: 2036 GKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPP 2095 K++V F+DD+NMP + YG P L+RQ +DH +WYD ++ + + Q + M P Sbjct: 2523 TKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPT 2582 Query: 2096 GGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNG 2155 G + R RHF + ++ +++ TI++ ILT HL +++Q+V Sbjct: 2583 SGSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAA 2640 Query: 2156 TMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRV 2215 + L+++ LPT K HY+FNLRD S + QG+ S E +T + RLW+HE RV Sbjct: 2641 ALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERV 2700 Query: 2216 YYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF-- 2273 Y D+++D D+ L + + F +L L F + +FC F Sbjct: 2701 YGDKMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQ 2746 Query: 2274 --HDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILK 2331 DPK Y + D+ L ++ L+ YN ++ MNLVLF A+ HI RI+RIL+ Sbjct: 2747 GIGDPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILE 2800 Query: 2332 QPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGE 2391 PR +ALLVGVGGSG+QS++RLAA+++ VFQ+ + KGY + DL K A Sbjct: 2801 SPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2860 Query: 2392 MQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTD 2451 + VFL TD+Q+ EE FL +++LL +GEIP LF DE + I M R + K+ + Sbjct: 2861 VPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMN 2916 Query: 2452 GSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQA 2511 + + FI+ R QL V+L SP+G R R RKFPA+VNC IDWF WPEDAL + Sbjct: 2917 DTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVS 2976 Query: 2512 VASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFK 2571 V++RFLEE E I+ HT+ ++S+ + +RYNY TP ++LE I ++ Sbjct: 2977 VSARFLEETEGIPVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQ 3036 Query: 2572 LLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIE 2631 LL KKR+E++ +R E GL KL S +SQV ++ +L +LK ++ D+++ ++ Sbjct: 3037 NLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVG 3096 Query: 2632 KESVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQD 2690 E+ +V+K EK + E + E + K + C+ DLA A P L +A ALDTL + Sbjct: 3097 IEAEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNN 3155 Query: 2691 ITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-R 2747 +T +KS SPP V V A+ IL T G KI + W AK ++G + Sbjct: 3156 LTELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDT 3204 Query: 2748 FLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVA 2807 FL SL ++DK++IP A + K Y NP F PE IR+ STAA GLC W I + + +V Sbjct: 3205 FLDSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVY 3263 Query: 2808 KIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVD 2867 VAPK+ L A EL A + L + + + E+ L+ L E +K + + D Sbjct: 3264 CDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEAD 3323 Query: 2868 LCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQ 2927 ++ + A +L+GGL E RW+ + + L GD+L+ S V+Y+G FT YR Sbjct: 3324 ATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRN 3383 Query: 2928 N-QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984 K W IP ++ + L + + TWN GLPSD S +N I+ N Sbjct: 3384 ELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNT 3443 Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044 RWPL++D Q Q KWIKN + + L I+L + Y+ +E I G +L+EN+GE +D Sbjct: 3444 ERWPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3502 Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104 P+L+PLL + T K+G I++GD +EY P FR + TK NPHY PE + TL+NF+ Sbjct: 3503 PVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFL 3560 Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164 +T +G++DQLL VVA+ERPDLE+ K L E K LKE+ED +L LS++ GN L Sbjct: 3561 VTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLG 3620 Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224 D ++ L ++K A+EI +K A+ TE KI+ R YRP A +S+L+F L DL I Sbjct: 3621 DTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKIN 3680 Query: 3225 PMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSF 3284 P+YQ+SL F +F +I+ + + + +R+ L D TYS+Y+ R LFE+DKL+F Sbjct: 3681 PVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLA 3740 Query: 3285 CLTINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKT 3342 +T +L ++ +N E FLL G+ +P +L + W I L ++ FK Sbjct: 3741 QVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKN 3796 Query: 3343 IRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFII 3402 + + WKK+ +S P E+FP+EW++K Q++ ++RCLRPD++ ++ F+ Sbjct: 3797 LDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVE 3855 Query: 3403 NRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSS 3460 ++G F+E + +K++ +S+ + F+LSPG DP+ + G+ KL + Sbjct: 3856 EKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHN 3915 Query: 3461 LSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWL 3520 +SLGQGQ +A L+ A ++G WV+LQN HL W+ TL+K E S S H D+R+++ Sbjct: 3916 VSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGS-HEDYRVFI 3974 Query: 3521 TSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEF 3575 ++ P+P+ P +L+N +K+TNE P G+ AN+ ++ + + C K EF Sbjct: 3975 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCTKEMEF 4031 Query: 3576 KKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRY 3635 K +L+ LC+FHA+V ERRKFG GWN Y FN DL IS+ L+ +L ++P++ LRY Sbjct: 4032 KCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRY 4091 Query: 3636 MTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEY 3695 + GE YGG +TDDWDRR R+ L ++ E++E + +PP+ D+K Y EY Sbjct: 4092 LFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEY 4148 Query: 3696 TKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGA---KSSDEVVNEV 3752 +P ++G++ NA+I ++ LF +L Q + +GA S +E V V Sbjct: 4149 IDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAV 4208 Query: 3753 ASDILGKLPNNFDIEAAMRR--YPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAI 3810 DIL K+P F++ M + T Y V QE R N L +R S + + Sbjct: 4209 LDDILEKIPETFNMAEIMAKAAEKTPYV----VVAFQECERMNILTNEMRRSLKELNLGL 4264 Query: 3811 KGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGP 3869 KG ++TD+E++ +++ +P+ W+ ++YPS+ L ++ D L R++ L+ W + Sbjct: 4265 KGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFAL 4324 Query: 3870 PPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHG 3927 P WL+GFF Q+FLT Q+ ARK P+D + EV + ++ PP +G +++G Sbjct: 4325 PTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYG 4384 Query: 3928 LFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVL 3987 LF++GA W+ + +AE+ K L +PV+++K + + Y P+YKT R Sbjct: 4385 LFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR---- 4440 Query: 3988 STTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022 +V L + + WI VALL Q+ Sbjct: 4441 -----GPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470 >gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo sapiens] Length = 4485 Score = 1946 bits (5040), Expect = 0.0 Identities = 1225/3730 (32%), Positives = 1949/3730 (52%), Gaps = 248/3730 (6%) Query: 400 PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458 P F +R+ LD D + F P L D FL + + ++ + V R+ +L +K + Sbjct: 897 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 951 Query: 459 TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513 + N + +E++ +++ E+ +++Y +L T + + NFL Sbjct: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1011 Query: 514 --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558 AE+ + + ++I Y+KL EE+ + G + C + Sbjct: 1012 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1071 Query: 559 ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611 AL+ + MF+ H V L D F ++A L+ P + L+E+ Sbjct: 1072 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1126 Query: 612 AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671 ++ KV+ + K + L Y P ++ L + + Sbjct: 1127 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185 Query: 672 KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGK 728 K+ ++ + L+ +C++F + + ++ E +SF D + + L K +L G Sbjct: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD-PNPYKSLNKVFLLKGI 1244 Query: 729 LDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPY 788 ++ + F + L + + + + +++ L++ V +++ W + Sbjct: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKTTKW 1297 Query: 789 HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848 +N +Q++ D + + + L+K + + V++ + + + + NP Sbjct: 1298 KDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPA 1353 Query: 849 LRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKM 908 +R RHW+ + + S+++T++ L +NL Y D I + A KE +EK ++ + Sbjct: 1354 IRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKAL 1413 Query: 909 ITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEG 968 + W +EF + TGT +L S + + L+D+ ++ Q + S ++ + K++ W+ Sbjct: 1414 DSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQ 1473 Query: 969 KLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027 KL ++ W +VQ TW +LE IF S DI +Q+P + +RF +++ ++ +M ++ Sbjct: 1474 KLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKT 1533 Query: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087 +V+ + + +L+ + L + K L EYLE KRL FPRF+F+S+ +LL+ILS Sbjct: 1534 PNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGN 1593 Query: 1088 DPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKWL 1144 DP V HL K F+ + K++F +K G + E + GQVE WL Sbjct: 1594 DPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWL 1653 Query: 1145 VELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK 1204 + M +++ +A Y + R W+ D+P +QI+WT EV A + Sbjct: 1654 NRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYP-------AQIWWTTEVGLAFARLEE 1706 Query: 1205 ALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260 E +K N+ Q++ ++TL+ G L+ +R+ + + +DVHARDV++ ++ + Sbjct: 1707 GYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VES 1763 Query: 1261 DSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGAL 1318 F W +QLR+ W E H + +A ++Y YEYLGN+PRLVITPLTDRCY TL +L Sbjct: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823 Query: 1319 HLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWAC 1378 HL +GGAP GPAGTGKTETTKDL +A+ VFNCS+ +DY + G +KGL GAW C Sbjct: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883 Query: 1379 FDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRS 1438 FDEFNRI +EVLSV+A Q+ +Q I A F G + L PT +FITMNPGYAGR+ Sbjct: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRA 1943 Query: 1439 ELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHY 1498 ELP+NLKALFR AM+VPD+ +I EI+L + GF+ AR L+ K + Y LC E LS Q HY Sbjct: 1944 ELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHY 2003 Query: 1499 DYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPG 1558 D+G+RA+KSVL AG+LK P+ E+ +L+R++ D N+PK ++ DLP+F G+ DLFP Sbjct: 2004 DWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPA 2063 Query: 1559 VKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSA 1618 + +P+ + IK + + LQ F K++Q+ E++ VRH IVG GK+ Sbjct: 2064 LDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQV 2123 Query: 1619 YRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAF 1678 + L ++ K + + L+PK+VT +L+G + V+ EW DG+ + R Sbjct: 2124 LKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2176 Query: 1679 ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEV 1738 A+ KW+I DG +D +WIE++NTV+DDNK L L S E I ++ M L+FE L Sbjct: 2177 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2236 Query: 1739 ASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIR 1798 A+PATVSR G++Y+ P LGW P++ SW+ +K +M LFD+ +P ++ +R Sbjct: 2237 ATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLDKLR 2293 Query: 1799 KHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVG 1858 K+++P + ++++++ L++C + E + + RE Y L F+F+ W+ G Sbjct: 2294 FGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFWAFG 2346 Query: 1859 ASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQF 1918 + D + + S N FK T+ FP +GTI+DY + Sbjct: 2347 GAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFDY-Y 2384 Query: 1919 VTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978 + K+ PW K+ P DV +V T +TIR M+LL P + VG Sbjct: 2385 IDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2443 Query: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038 GTGKSV + + L LN + Y + F+ TT+A Q ++ L+K+ +GPP K+ Sbjct: 2444 GTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502 Query: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGG 2098 +V F+DD+NMP + YG P L+RQ +DH +WYD ++ + + Q + M P G Sbjct: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562 Query: 2099 RNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMT 2158 + R RHF + ++ +++ TI++ ILT HL +++Q+V + Sbjct: 2563 FT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALA 2620 Query: 2159 LYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYD 2218 L+++ LPT K HY+FNLRD S + QG+ S E +T + RLW+HE RVY D Sbjct: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680 Query: 2219 RLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF----H 2274 +++D D+ L + + F +L L F + +FC F Sbjct: 2681 KMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQGIG 2726 Query: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334 DPK Y + D+ L ++ L+ YN ++ MNLVLF A+ HI RI+RIL+ PR Sbjct: 2727 DPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPR 2780 Query: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394 +ALLVGVGGSG+QS++RLAA+++ VFQ+ + KGY + DL K A + Sbjct: 2781 GNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPS 2840 Query: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454 VFL TD+Q+ EE FL +++LL +GEIP LF DE + I M R + K+ + + Sbjct: 2841 VFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMNDTR 2896 Query: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514 + FI+ R QL V+L SP+G R R RKFPA+VNC IDWF WPEDAL +V++ Sbjct: 2897 ETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSA 2956 Query: 2515 RFLEEIE-MSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573 RFLEE E + E++ HT+ ++S+ + +RYNY TP ++LE I ++ L Sbjct: 2957 RFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNL 3016 Query: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633 L KKR+E++ +R E GL KL S +SQV ++ +L +LK ++ D+++ ++ E Sbjct: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076 Query: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQDIT 2692 + +V+K EK + E + E + K + C+ DLA A P L +A ALDTL ++T Sbjct: 3077 AEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLT 3135 Query: 2693 VVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-RFL 2749 +KS SPP V V A+ IL T G KI + W AK ++G + FL Sbjct: 3136 ELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDTFL 3184 Query: 2750 QSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKI 2809 SL ++DK++IP A + K Y NP F PE IR+ STAA GLC W I + + +V Sbjct: 3185 DSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD 3243 Query: 2810 VAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLC 2869 VAPK+ L A EL A + L + + + E+ L+ L E +K + + D Sbjct: 3244 VAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADAT 3303 Query: 2870 SKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN- 2928 ++ + A +L+GGL E RW+ + + L GD+L+ S V+Y+G FT YR Sbjct: 3304 NRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNEL 3363 Query: 2929 QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARR 2986 K W IP ++ + L + + TWN GLPSD S +N I+ N R Sbjct: 3364 MEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTER 3423 Query: 2987 WPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPI 3046 WPL++D Q Q KWIKN + + L I+L + Y+ +E I G +L+EN+GE +DP+ Sbjct: 3424 WPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPV 3482 Query: 3047 LEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMIT 3106 L+PLL + T K+G I++GD +EY P FR + TK NPHY PE + TL+NF++T Sbjct: 3483 LDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540 Query: 3107 PEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDE 3166 +G++DQLL VVA+ERPDLE+ K L E K LKE+ED +L LS++ GN L D Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600 Query: 3167 TAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPM 3226 ++ L ++K A+EI +K A+ TE KI+ R YRP A +S+L+F L DL I P+ Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660 Query: 3227 YQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCL 3286 YQ+SL F +F +I+ + + + +R+ L D TYS+Y+ R LFE+DKL+F + Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720 Query: 3287 TINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIR 3344 T +L ++ +N E FLL G+ +P +L + W I L ++ FK + Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKNLD 3776 Query: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404 + WKK+ +S P E+FP+EW++K Q++ ++RCLRPD++ ++ F+ + Sbjct: 3777 SDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEK 3835 Query: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSSLS 3462 +G F+E + +K++ +S+ + F+LSPG DP+ + G+ KL ++S Sbjct: 3836 MGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVS 3895 Query: 3463 LGQGQGPIAMKMLEKAVKEGTWVVLQ--------NCHLATSWMPTLEKVCEELSPESTHP 3514 LGQGQ +A L+ A ++G WV+LQ N HL W+ TL+K E S S H Sbjct: 3896 LGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HE 3954 Query: 3515 DFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSC 3569 D+R+++++ P+P+ P +L+N +K+TNE P G+ AN+ ++ + + C Sbjct: 3955 DYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMC 4011 Query: 3570 KKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELP 3629 K EFK +L+ LC+FHA+V ERRKFG GWN Y FN DL IS+ L+ +L ++P Sbjct: 4012 TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVP 4071 Query: 3630 YEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDH 3689 ++ LRY+ GE YGG +TDDWDRR R+ L ++ E++E + +PP+ D+ Sbjct: 4072 WDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDY 4128 Query: 3690 KSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDE 3747 K Y EY +P ++G++ NA+I ++ LF +L Q + +GAG S E Sbjct: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188 Query: 3748 ------------------------------VVNEVASDILGKLPNNFDIEAAMRR--YPT 3775 V V DIL K+P F++ M + T Sbjct: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248 Query: 3776 TYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEM 3835 Y V QE R N L +R S + +KG ++TD+E++ +++ +P+ Sbjct: 4249 PYV----VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDT 4304 Query: 3836 WMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYAR 3894 W+ ++YPS+ L ++ D L R++ L+ W + P WL+GFF Q+FLT Q+ AR Sbjct: 4305 WVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMAR 4364 Query: 3895 KYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYD 3952 K P+D + EV + ++ PP +G +++GLF++GA W+ + +AE+ K L Sbjct: 4365 KNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTP 4424 Query: 3953 TVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWI 4012 +PV+++K + + Y P+YKT R +V L + + WI Sbjct: 4425 AMPVIFIKAIPVDRMETKNIYECPVYKTRIR---------GPTYVWTFNLKTKEKAAKWI 4475 Query: 4013 GRGVALLCQL 4022 VALL Q+ Sbjct: 4476 LAAVALLLQV 4485 >gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo sapiens] Length = 4485 Score = 1945 bits (5039), Expect = 0.0 Identities = 1224/3730 (32%), Positives = 1949/3730 (52%), Gaps = 248/3730 (6%) Query: 400 PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458 P F +R+ LD D + F P L D FL + + ++ + V R+ +L +K + Sbjct: 897 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 951 Query: 459 TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513 + N + +E++ +++ E+ +++Y +L T + + NFL Sbjct: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1011 Query: 514 --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558 AE+ + + ++I Y+KL EE+ + G + C + Sbjct: 1012 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1071 Query: 559 ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611 AL+ + MF+ H V L D F ++A L+ P + L+E+ Sbjct: 1072 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1126 Query: 612 AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671 ++ KV+ + K + L Y P ++ L + + Sbjct: 1127 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185 Query: 672 KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGK 728 K+ ++ + L+ +C++F + + ++ E +SF D + + L K +L G Sbjct: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD-PNPYKSLNKVFLLKGI 1244 Query: 729 LDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPY 788 ++ + F + L + + + + +++ L++ V +++ W + Sbjct: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKTTKW 1297 Query: 789 HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848 +N +Q++ D + + + L+K + + V++ + + + + NP Sbjct: 1298 KDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPA 1353 Query: 849 LRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKM 908 +R RHW+ + + S+++T++ L +NL Y D I + A KE +EK ++ + Sbjct: 1354 IRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKAL 1413 Query: 909 ITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEG 968 + W +EF + TGT +L S + + L+D+ ++ Q + S ++ + K++ W+ Sbjct: 1414 DSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQ 1473 Query: 969 KLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027 KL ++ W +VQ TW +LE IF S DI +Q+P + +RF +++ ++ +M ++ Sbjct: 1474 KLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKT 1533 Query: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087 +V+ + + +L+ + L + K L EYLE KRL FPRF+F+S+ +LL+ILS Sbjct: 1534 PNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGN 1593 Query: 1088 DPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKWL 1144 DP V HL K F+ + K++F +K G + E + GQVE WL Sbjct: 1594 DPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWL 1653 Query: 1145 VELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK 1204 + M +++ +A Y + R W+ D+P +QI+WT EV A + Sbjct: 1654 NRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYP-------AQIWWTTEVGLAFARLEE 1706 Query: 1205 ALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260 E ++ N+ Q++ ++TL+ G L+ +R+ + + +DVHARDV++ ++ + Sbjct: 1707 GYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMI---VES 1763 Query: 1261 DSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGAL 1318 F W +QLR+ W E H + +A ++Y YEYLGN+PRLVITPLTDRCY TL +L Sbjct: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823 Query: 1319 HLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWAC 1378 HL +GGAP GPAGTGKTETTKDL +A+ VFNCS+ +DY + G +KGL GAW C Sbjct: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883 Query: 1379 FDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRS 1438 FDEFNRI +EVLSV+A Q+ +Q I A F G + L PT +FITMNPGYAGR+ Sbjct: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRA 1943 Query: 1439 ELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHY 1498 ELP+NLKALFR AM+VPD+ +I EI+L + GF+ AR L+ K + Y LC E LS Q HY Sbjct: 1944 ELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHY 2003 Query: 1499 DYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPG 1558 D+G+RA+KSVL AG+LK P+ E+ +L+R++ D N+PK ++ DLP+F G+ DLFP Sbjct: 2004 DWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPA 2063 Query: 1559 VKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSA 1618 + +P+ + IK + + LQ F K++Q+ E++ VRH IVG GK+ Sbjct: 2064 LDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQV 2123 Query: 1619 YRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAF 1678 + L ++ K + + L+PK+VT +L+G + V+ EW DG+ + R Sbjct: 2124 LKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2176 Query: 1679 ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEV 1738 A+ KW+I DG +D +WIE++NTV+DDNK L L S E I ++ M L+FE L Sbjct: 2177 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2236 Query: 1739 ASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIR 1798 A+PATVSR G++Y+ P LGW P++ SW+ +K +M LFD+ +P ++ +R Sbjct: 2237 ATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLDKLR 2293 Query: 1799 KHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVG 1858 K+++P + ++++++ L++C + E + + RE Y L F+F+ W+ G Sbjct: 2294 FGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFWAFG 2346 Query: 1859 ASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQF 1918 + D + + S N FK T+ FP +GTI+DY + Sbjct: 2347 GAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFDY-Y 2384 Query: 1919 VTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978 + K+ PW K+ P DV +V T +TIR M+LL P + VG Sbjct: 2385 IDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2443 Query: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038 GTGKSV + + L LN + Y + F+ TT+A Q ++ L+K+ +GPP K+ Sbjct: 2444 GTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502 Query: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGG 2098 +V F+DD+NMP + YG P L+RQ +DH +WYD ++ + + Q + M P G Sbjct: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562 Query: 2099 RNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMT 2158 + R RHF + ++ +++ TI++ ILT HL +++Q+V + Sbjct: 2563 FT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALA 2620 Query: 2159 LYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYD 2218 L+++ LPT K HY+FNLRD S + QG+ S E +T + RLW+HE RVY D Sbjct: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680 Query: 2219 RLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF----H 2274 +++D D+ L + + F +L L F + +FC F Sbjct: 2681 KMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQGIG 2726 Query: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334 DPK Y + D+ L ++ L+ YN ++ MNLVLF A+ HI RI+RIL+ PR Sbjct: 2727 DPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPR 2780 Query: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394 +ALLVGVGGSG+QS++RLAA+++ VFQ+ + KGY + DL K A + Sbjct: 2781 GNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPS 2840 Query: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454 VFL TD+Q+ EE FL +++LL +GEIP LF DE + I M R + K+ + + Sbjct: 2841 VFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMNDTR 2896 Query: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514 + FI+ R QL V+L SP+G R R RKFPA+VNC IDWF WPEDAL +V++ Sbjct: 2897 ETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSA 2956 Query: 2515 RFLEEIE-MSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573 RFLEE E + E++ HT+ ++S+ + +RYNY TP ++LE I ++ L Sbjct: 2957 RFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNL 3016 Query: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633 L KKR+E++ +R E GL KL S +SQV ++ +L +LK ++ D+++ ++ E Sbjct: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076 Query: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQDIT 2692 + +V+K EK + E + E + K + C+ DLA A P L +A ALDTL ++T Sbjct: 3077 AEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLT 3135 Query: 2693 VVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-RFL 2749 +KS SPP V V A+ IL T G KI + W AK ++G + FL Sbjct: 3136 ELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDTFL 3184 Query: 2750 QSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKI 2809 SL ++DK++IP A + K Y NP F PE IR+ STAA GLC W I + + +V Sbjct: 3185 DSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD 3243 Query: 2810 VAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLC 2869 VAPK+ L A EL A + L + + + E+ L+ L E +K + + D Sbjct: 3244 VAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADAT 3303 Query: 2870 SKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN- 2928 ++ + A +L+GGL E RW+ + + L GD+L+ S V+Y+G FT YR Sbjct: 3304 NRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNEL 3363 Query: 2929 QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARR 2986 K W IP ++ + L + + TWN GLPSD S +N I+ N R Sbjct: 3364 MEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTER 3423 Query: 2987 WPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPI 3046 WPL++D Q Q KWIKN + + L I+L + Y+ +E I G +L+EN+GE +DP+ Sbjct: 3424 WPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPV 3482 Query: 3047 LEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMIT 3106 L+PLL + T K+G I++GD +EY P FR + TK NPHY PE + TL+NF++T Sbjct: 3483 LDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540 Query: 3107 PEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDE 3166 +G++DQLL VVA+ERPDLE+ K L E K LKE+ED +L LS++ GN L D Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600 Query: 3167 TAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPM 3226 ++ L ++K A+EI +K A+ TE KI+ R YRP A +S+L+F L DL I P+ Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660 Query: 3227 YQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCL 3286 YQ+SL F +F +I+ + + + +R+ L D TYS+Y+ R LFE+DKL+F + Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720 Query: 3287 TINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIR 3344 T +L ++ +N E FLL G+ +P +L + W I L ++ FK + Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKNLD 3776 Query: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404 + WKK+ +S P E+FP+EW++K Q++ ++RCLRPD++ ++ F+ + Sbjct: 3777 SDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEK 3835 Query: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSSLS 3462 +G F+E + +K++ +S+ + F+LSPG DP+ + G+ KL ++S Sbjct: 3836 MGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVS 3895 Query: 3463 LGQGQGPIAMKMLEKAVKEGTWVVLQ--------NCHLATSWMPTLEKVCEELSPESTHP 3514 LGQGQ +A L+ A ++G WV+LQ N HL W+ TL+K E S S H Sbjct: 3896 LGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGS-HE 3954 Query: 3515 DFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSC 3569 D+R+++++ P+P+ P +L+N +K+TNE P G+ AN+ ++ + + C Sbjct: 3955 DYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMC 4011 Query: 3570 KKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELP 3629 K EFK +L+ LC+FHA+V ERRKFG GWN Y FN DL IS+ L+ +L ++P Sbjct: 4012 TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVP 4071 Query: 3630 YEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDH 3689 ++ LRY+ GE YGG +TDDWDRR R+ L ++ E++E + +PP+ D+ Sbjct: 4072 WDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDY 4128 Query: 3690 KSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDE 3747 K Y EY +P ++G++ NA+I ++ LF +L Q + +GAG S E Sbjct: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188 Query: 3748 ------------------------------VVNEVASDILGKLPNNFDIEAAMRR--YPT 3775 V V DIL K+P F++ M + T Sbjct: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248 Query: 3776 TYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEM 3835 Y V QE R N L +R S + +KG ++TD+E++ +++ +P+ Sbjct: 4249 PYV----VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDT 4304 Query: 3836 WMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYAR 3894 W+ ++YPS+ L ++ D L R++ L+ W + P WL+GFF Q+FLT Q+ AR Sbjct: 4305 WVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMAR 4364 Query: 3895 KYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYD 3952 K P+D + EV + ++ PP +G +++GLF++GA W+ + +AE+ K L Sbjct: 4365 KNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTP 4424 Query: 3953 TVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWI 4012 +PV+++K + + Y P+YKT R +V L + + WI Sbjct: 4425 AMPVIFIKAIPVDRMETKNIYECPVYKTRIR---------GPTYVWTFNLKTKEKAAKWI 4475 Query: 4013 GRGVALLCQL 4022 VALL Q+ Sbjct: 4476 LAAVALLLQV 4485 >gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens] Length = 4486 Score = 1941 bits (5029), Expect = 0.0 Identities = 1194/3573 (33%), Positives = 1893/3573 (52%), Gaps = 200/3573 (5%) Query: 509 VDNFLAENHSYEKIIDEICKYQ--KLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADI 566 + F + SYE + +E+C+ + K+ + I+ + + ++KR + Sbjct: 1055 LSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLN---------IIKRWSL 1105 Query: 567 ICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAE---LMEMKAYIQKVEVTDMI 623 + + L DH + D F + +E L + L+E+ ++ V+ Sbjct: 1106 LFKQHLV----DHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQS- 1160 Query: 624 ELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKI---IKEKIEQ 680 ++ K + L Y + L +VF+ + E + +K+ +K+++ Sbjct: 1161 NTDEMFEPLKQTIELLKTY------EQELPETVFKQLEELPEKWNNIKKVAITVKQQVAP 1214 Query: 681 YQEG----LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGKLDLAAD 734 Q L+ RC F E + + +Q E + F + Q LD Sbjct: 1215 LQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQM-----------LDARHI 1263 Query: 735 KIEQFNAEEEAFGWLPSV-------YPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGP 787 +I+Q + + S+ Y Q ++ + + L++T +S+ AW P Sbjct: 1264 EIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTP 1323 Query: 788 YHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNP 847 + +N + +E + + R + L+K A + S V + + + + NP Sbjct: 1324 WRNINVEAMELECKQFARHIRNLDKEVR----AWDAFTGLESTVWNTLSSLRAVAELQNP 1379 Query: 848 GLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEK 907 +R RHW + G D+T++ L + L Y D GI + A+KE +EK +++ Sbjct: 1380 AIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKE 1439 Query: 908 MITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWE 967 + T W +EF + T +L S +++ +L+D+ ++ Q + S ++ + +++ W+ Sbjct: 1440 LQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQ 1499 Query: 968 GKLLLLQEILDEWLKVQATWLYLEPIFS-SPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQ 1026 KL + ++ W +VQ TW +LE IF+ S DI +Q+P++ +RF +D ++++ + Sbjct: 1500 KKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQK 1559 Query: 1027 DKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSET 1086 +V+ + E+L+ L L K L EYL+ KRL FPRF+FLS+ +LL+ILS Sbjct: 1560 IPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNG 1619 Query: 1087 KDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKW 1143 P +VQ HL K F+ +AK+ F K+S G + E + GQVE W Sbjct: 1620 TAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIW 1679 Query: 1144 LVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTA---IP 1200 L + M ++ + AY + R W+ D P Q L +QI+WT EV A + Sbjct: 1680 LNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLE 1739 Query: 1201 MGIK-ALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNIS 1259 G + A++ Y K Q+ ++T++ G+LS +R + + +DVHARDV++ ++ + + Sbjct: 1740 EGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVD 1799 Query: 1260 DDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGA 1317 + F WLSQLR+ W + H + +A Y YEYLGN+PRLVITPLTDRCY TL + Sbjct: 1800 NAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQS 1859 Query: 1318 LHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWA 1377 LHL + GAP GPAGTGKTETTKDL +A+ VFNCS+ +DY + G +KGL GAW Sbjct: 1860 LHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWG 1919 Query: 1378 CFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGR 1437 CFDEFNRI +EVLSVVA Q+ +IQ I F G E+ L+P+ +FITMNPGYAGR Sbjct: 1920 CFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGR 1979 Query: 1438 SELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHH 1497 +ELP+NLK+LFR AM+VPD+ +I EI+L + GF+ A+ L+ K + Y+LC E LS Q H Sbjct: 1980 TELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDH 2039 Query: 1498 YDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFP 1557 YD+G+RA+KSVL AG+LK P+ E+ +L+RS+ D N+PK ++ D+P+F G+ DLFP Sbjct: 2040 YDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFP 2099 Query: 1558 GVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTS 1617 + +P+ + A ++ + LQ F K++Q+ E++ VRH +VG GK+ Sbjct: 2100 ALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQ 2159 Query: 1618 AYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRA 1677 R L +M+ V T LNPK+VT +L+G + + EW DG+ + R Sbjct: 2160 VLRSLHKTYQ------IMKRRPVW-TDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRE 2212 Query: 1678 FASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLE 1737 A+ KW++ DG +D +WIE++NTV+DDNK L L S E I ++P M L+FE L Sbjct: 2213 LANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLR 2272 Query: 1738 VASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFI 1797 A+PATVSR G++Y+ P LGW P + SW+ ++ + LFD+ +P ++ + Sbjct: 2273 TATPATVSRAGILYINPADLGWNPPVSSWIEKREIQT---ERANLTILFDKYLPTCLDTL 2329 Query: 1798 RKHTKELSPTSDTNLVRSLMNLIDCFM---DDFADEVKLKERNDRETYSLLEGIFLFSLI 1854 R K++ P + ++V+ + +L++C + D AD K + E F+F+ I Sbjct: 2330 RTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPK----------EIYEHYFVFAAI 2379 Query: 1855 WSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIY 1914 W+ G + D + + + S FK TV FP +GTI+ Sbjct: 2380 WAFGGAMVQDQLVDY--------RAEFSKWWLTEFK-------------TVKFPSQGTIF 2418 Query: 1915 DYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIF 1974 DY ++ K+EPW K + + P ++ +V T +TIR ME L Q+P + Sbjct: 2419 DY-YIDPETKKFEPWSKLVPQFEFDP-EMPLQACLVHTSETIRVCYFMERLMARQRPVML 2476 Query: 1975 VGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPP 2034 VG GTGKSV + L L+ E Y + F+ TT+A Q ++ L+K+ +GPP Sbjct: 2477 VGTAGTGKSV-LVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPP 2535 Query: 2035 LGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGP 2094 K+++ F+DD+NMP + YG P ++RQ LD+ +WYD S+ ++ ++Q + M P Sbjct: 2536 GNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNP 2595 Query: 2095 PGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVN 2154 G + PR RHF++ ++ ++ +I+S ILT HL++ FP +++ Sbjct: 2596 TAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKL-GNFPASLQKSIPPLID 2653 Query: 2155 GTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLR 2214 + +++ LPT K HY+FNLRDF+ + QG+ S E ++T + RL++HE R Sbjct: 2654 LALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNR 2713 Query: 2215 VYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFH 2274 VY D++++ D L + IQ + ++D + ++ N ++C F Sbjct: 2714 VYRDKMVEEKDFD-LFDKIQTEVLKKTFDDIEDPVEQTQSPN------------LYCHFA 2760 Query: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334 + E Y + + L + LE +N ++ M+LVLF A+ H+ I+RIL+ PR Sbjct: 2761 NGIGE-PKYMPVQSWELLTQTLVEALENHNEVN-TVMDLVLFEDAMRHVCHINRILESPR 2818 Query: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394 +ALLVGVGGSG+QS+TRLAA ++ VFQ+ + KGY ++ DL + K + Sbjct: 2819 GNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNT 2878 Query: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454 VFL TD Q+ +E FL +++LL +GEIP+L++ DE + I +R + + + Sbjct: 2879 VFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNREN-- 2936 Query: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514 + FID R QL V L SP+G+ R R RKFPA+VNC I WF WP+ AL++V+ Sbjct: 2937 --CWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSL 2994 Query: 2515 RFLEEIEMSEEIRDGCIDMCKSF-HTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573 RFL+ E E I +F HTS S+S+ QRYNY TP S+LE I ++ L Sbjct: 2995 RFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSL 3054 Query: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633 L + R E+ +R E GL KL S S+QV ++ +L A +LK +++ D+++ ++ E Sbjct: 3055 LHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVE 3114 Query: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITV 2693 + +V++ + + +E + K + +C+ DLA A P L +A AAL+TL ++T Sbjct: 3115 TDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTE 3174 Query: 2694 VKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDM-RFLQSL 2752 +KS SPP V V A+ +L P G K + W AK + + FL SL Sbjct: 3175 LKSFGSPPLAVSNVSAAVMVLMA--------PRGRVPK-DRSWKAAKVTMAKVDGFLDSL 3225 Query: 2753 HEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAP 2812 ++K+NI + IR Y+ +P+F PE + S AA GLC WVI + + +V V P Sbjct: 3226 INFNKENIHENCLKAIRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEP 3284 Query: 2813 KKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKK 2872 K+ L A +L A + L +A + + + LA+L E K + + ++ + Sbjct: 3285 KRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVT 3344 Query: 2873 LERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN-QTK 2931 + A +L+GGL E RW+ Q L GDIL+ + ++YLG FT YRQ+ + Sbjct: 3345 ISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDR 3404 Query: 2932 EWTTLCK--GRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPL 2989 W IP + + L + + W GLP+D S++N I++N RWPL Sbjct: 3405 TWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPL 3464 Query: 2990 MIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEP 3049 M+DPQ Q KWIKN + L V ++ + Y++ +E ++ G VL+EN+ E +DP+L P Sbjct: 3465 MVDPQLQGIKWIKN-KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGP 3523 Query: 3050 LLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEG 3109 LL ++ K+G I++GD EY P FR + TKL NPHY PE + TL+NF +T +G Sbjct: 3524 LLGREVIKKG--RFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDG 3581 Query: 3110 MQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAI 3169 ++DQLL VV+ ERPDLE+ K L Q K LK +ED +L LSS+ GN L + + Sbjct: 3582 LEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLV 3641 Query: 3170 KILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQY 3229 + L +K A E+ +K + A+ TE KI+ R YRP A +S+L+F + DL+ I PMYQ+ Sbjct: 3642 ENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQF 3701 Query: 3230 SLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTIN 3289 SL F +F ++E + E L +R+ L D T+S+Y R LFE DKL + LT Sbjct: 3702 SLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQ 3761 Query: 3290 LLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMR 3349 +LL R +N E FLL + A+ +L ++W + L + F + R+ Sbjct: 3762 ILLMNREVNAVELDFLLRSPV--QTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEG 3819 Query: 3350 LKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAF 3409 WKK +S P E P+EW++K QR+ ++R +RPD++ L++F+ +LG + Sbjct: 3820 SAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKY 3878 Query: 3410 IEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQG------YGGSKLSSLSL 3463 + D A +F +S P+ F+LSPG DP LK + QG + ++SL Sbjct: 3879 VVGRALDFATSFEESGPATPMFFILSPGVDP----LKDVESQGRKLGYTFNNQNFHNVSL 3934 Query: 3464 GQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSY 3523 GQGQ +A L+ A K+G WV+LQN HL W+ TLEK EE S E++HP+FR+++++ Sbjct: 3935 GQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENSHPEFRVFMSAE 3993 Query: 3524 PSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKL 3578 P+P+ P +L+N +K+TNE P G+ AN+ ++ +D + + C + EFK + Sbjct: 3994 PAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA--LDNFTQ-DTLEMCSRETEFKSI 4050 Query: 3579 LYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTG 3638 L+ LC+FHA+V ERRKFGP GWN Y FN DL ISV L+ FL ++PY+ LRY+ G Sbjct: 4051 LFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFG 4110 Query: 3639 ECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKT 3698 E YGG +TDDWDRR R+ L +F PE++E + + + +P + D+ Y +Y Sbjct: 4111 EIMYGGHITDDWDRRLCRTYLGEFIRPEMLEG---ELSLAPGFPLPGNMDYNGYHQYIDA 4167 Query: 3699 LPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSA----GAGAKSSDEVVNEVAS 3754 +P ++G++ NA+I ++ LF +L Q R + GAGA + +E V + Sbjct: 4168 ELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGA-TREEKVKALLE 4226 Query: 3755 DILGKLPNNFDIEAAMRRYP--TTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKG 3812 +IL ++ + F+I M + T Y V QE GR N L + I+ S ++ +KG Sbjct: 4227 EILERVTDEFNIPELMAKVEERTPYI----VVAFQECGRMNILTREIQRSLRELELGLKG 4282 Query: 3813 LAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWY-EVGPPP 3871 M++ +E + +++ +PE W ++YPS L ++ D L R+K L+ W + P Sbjct: 4283 ELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPS 4342 Query: 3872 VFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLF 3929 WL+GFF Q+FLT Q+ ARK P+D + ++ + +E++ PP +G +IHGLF Sbjct: 4343 TVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLF 4402 Query: 3930 LDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLST 3989 ++GA W+ + + E+ K L +PVM++K R Y P+YKTS+R Sbjct: 4403 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR------ 4456 Query: 3990 TGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022 +V L + + W+ GVALL Q+ Sbjct: 4457 ---GPTYVWTFNLKTKENPSKWVLAGVALLLQI 4486 >gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] Length = 4624 Score = 1918 bits (4968), Expect = 0.0 Identities = 1213/3682 (32%), Positives = 1907/3682 (51%), Gaps = 202/3682 (5%) Query: 409 DNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEI 468 D+D E EL D ++I +V+ V+TK Y K S++K +L+ I Sbjct: 1076 DSDVEMGENELQDTLEI---------ASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTI 1126 Query: 469 VDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICK 528 +++ K KEVI + + +Y+ + + E + F+ ++ + +I Sbjct: 1127 INSTK---KEVITS--------MDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILY 1175 Query: 529 YQKLIEEI----QYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNT 584 +Q L +EI +Y + +I L + + + A K ++ G+ K +R E Sbjct: 1176 FQNLEQEINAEPEYVCVGSIAL--YTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIF 1233 Query: 585 RLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVN 644 L +EF K L+ P + + + K + I ++ ++ + A L Y Sbjct: 1234 MLIEEFN----KKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGL 1289 Query: 645 FSPADM--RLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQ 702 + +++ + W + E ++ K+ Q K + + +E + + Sbjct: 1290 LIAREEIDKVDTLHYAWEKLLARAGE-----VQNKLVSLQPSFK---KELISAVEVFLQD 1341 Query: 703 SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQ-------FNAEEEAFGWLPSVYPQ 755 +FY DL K Q + +L + ++ + + EE FG + YPQ Sbjct: 1342 CHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQ 1401 Query: 756 RKKIQDGLNPYLR---LYETAVEFSSNYR--AWTEGPYHKVNPDQVEADIGNYWRGLYKL 810 +I+ LN + LY + +E ++Y W+E K+N + +E + KL Sbjct: 1402 LLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLE-----FQNRCRKL 1456 Query: 811 EKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDD 870 + D L + KK+ ++DF + PL++ + + + RHWE ++ + G+ L ++ Sbjct: 1457 PRALKDWQAFLDL-KKI---IDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNE 1512 Query: 871 S-TVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFI 929 S + + ++ L Y + E I +A KE +E+ ++++I EWD F S++ G + Sbjct: 1513 SFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELL 1572 Query: 930 LA--SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATW 987 L S EI ++D ++ ++ + + P++ Q+++W L +I++ W+ VQ W Sbjct: 1573 LRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLW 1632 Query: 988 LYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML-ERLKKS 1046 +YLE +F DI Q+P+E +RF+ +DK+W IM + V+ D L + L Sbjct: 1633 IYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHL 1692 Query: 1047 NELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKV 1106 + LE+ K L YLEKKRL FPRFFF+S+ LLEIL + D +Q HL F+ I V Sbjct: 1693 LDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSV 1752 Query: 1107 EFTETL--DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDAT- 1163 +F E + I + S EGE +EL + + A G VE WL L +S+H V A Sbjct: 1753 KFHEKIYDRILSISSQEGETIELDKPVM---AEGNVEVWLNSLLEESQSSLHLVIRQAAA 1809 Query: 1164 -FAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAI---PMGIKALEQYLKTCNRQIDD 1219 T ++ ++ +P Q L Q+ WT++ + A+ K +++ + ++ Sbjct: 1810 NIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNT 1869 Query: 1220 IVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENH- 1278 ++ + LS RV L+ + VH RD+ L +I DFEWL Q R+Y+ E+ Sbjct: 1870 LIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSD 1929 Query: 1279 -LETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTET 1337 + + + Y E+LG + RLVITPLTDRCY TL AL + +GGAP GPAGTGKTET Sbjct: 1930 KMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTET 1989 Query: 1338 TKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQI 1397 TKD+ + + K VVFNCSD +D+ LG+ FKGL G+W CFDEFNRIDL VLSV AQQI Sbjct: 1990 TKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQI 2049 Query: 1398 LTIQRGINAGADILMF-EGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVP 1456 I +F +G + ++P +F+TMNPGYAGR ELP+NLK FR+VAMMVP Sbjct: 2050 SIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVP 2109 Query: 1457 DYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLK 1516 D +I + L SCGF+ L+ K Y+LC EQLS Q HYD+G+R + SVL G K Sbjct: 2110 DRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAK 2169 Query: 1517 LKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDN 1576 P + E +++R + D+NL K + D PLF + DLFP + L K Y +L AAI Sbjct: 2170 RANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQ 2229 Query: 1577 CASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLME 1636 L + K++Q++E VRHG M +G GKT+ L A+ D C K E Sbjct: 2230 VEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTD-CGKPHRE 2288 Query: 1637 ENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVD 1696 +NPK++T Q++G+ D +++W+DG+ + +R + + W+I DGPVD Sbjct: 2289 MR------MNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVD 2342 Query: 1697 AVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHM 1756 A+WIEN+N+VLDDNK L L +G+ I M+P +IFEP +++ ASPATVSR GM++M + Sbjct: 2343 AIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSI 2402 Query: 1757 LGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSL 1816 L W P++ ++ + I ++ F + ++ + + L T + L Sbjct: 2403 LDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINML 2462 Query: 1817 MNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILREL 1876 LI LKE+ + + L +F+F+L+WS GA+ D R + LR Sbjct: 2463 QGLIP-----------LKEQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLR-- 2509 Query: 1877 MESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKE- 1935 + T + L P T +DY +G W W + +E Sbjct: 2510 ------------------SRPTGTLELPPPAGPGDTAFDYYVAPDGT--WTHWNTRTQEY 2549 Query: 1936 APPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLN 1995 P + I+VP +D +R L++ + K + +G GT K+V I F+ ++ + Sbjct: 2550 LYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFM-SKYD 2608 Query: 1996 KEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYG 2055 E + +NFS+ TT Q + S +DKR +GPP GK+M VF+DDVNMP +G Sbjct: 2609 PECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWG 2668 Query: 2056 AQPPIELLRQWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIIT 2114 Q E++RQ ++ +Y+L K +VDIQ + AM PGGGRN + R R F+I Sbjct: 2669 DQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFN 2728 Query: 2115 INEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKS 2174 S+ S+ IF I H F +E D T++V T L++ +LPTPAK Sbjct: 2729 CTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKF 2788 Query: 2175 HYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQ 2234 HY+FNLRD SRV QG+ + E + + +LW HE RV DR ++D +W + Sbjct: 2789 HYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALV 2848 Query: 2235 EILRNYMYEDFHELFQR------LDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIAD 2288 ++ E+ L +DF D A + D PK Y I Sbjct: 2849 SLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEE--ADAETPKI----YEPIES 2902 Query: 2289 VDNLRMIVEIHLEEYN-NISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGR 2347 +L+ + + L+ YN +I M++V F A+ H+ +ISR+++ P+ +ALLVGVGGSG+ Sbjct: 2903 FSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGK 2962 Query: 2348 QSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEES 2407 QS+TRLA+ +A Y FQ+ +++ Y+T+ EDLKV+ R + F+FTD +IK+ES Sbjct: 2963 QSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDES 3022 Query: 2408 FLEDVSNLLNAGEIPNLFALDEKQEI-CDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCR 2466 FLE ++N+L++GE+ NLFA DE EI D + ++ + T+ + L + F+ R Sbjct: 3023 FLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNEN---LHDYFMSRVR 3079 Query: 2467 SQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLE--EIEMSE 2524 LH+VL SP+G+ FRNR KFPAL++ CTIDWF WP+DAL AV+ FL +I+ S Sbjct: 3080 QNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSL 3139 Query: 2525 EIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKM 2584 EI+ + SF + +F +R +VTP SYL I +K + +K EV + Sbjct: 3140 EIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTL 3199 Query: 2585 KKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIV 2644 R GLEKL AS VA + ELEA +L+VA+ + D M+ KE A+ + V Sbjct: 3200 ANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKAD----MVLKEVTMKAQAAEKV 3255 Query: 2645 KADETIANE--QAMASKAIKDECDAD--LAGALPILESALAALDTLTAQDITVVKSMKSP 2700 KA+ + QA+ KD+ A+ L A P LE A AAL T+ DI V+++ P Sbjct: 3256 KAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRP 3315 Query: 2701 PAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNI 2760 P + +M+ + +L K + + W + +L+ FLQ+L ++ KD I Sbjct: 3316 PHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPS-WQESLKLMTAGNFLQNLQQFPKDTI 3374 Query: 2761 PPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAA 2820 + + Y PD+ E + GLC W AM S+ + K V P K L Sbjct: 3375 NEEVIEFLSP-YFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQ 3433 Query: 2821 EGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLI 2880 E +AM L+K QA L + Q +L +Q E +K L + C K++ A LI Sbjct: 3434 ENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLI 3493 Query: 2881 GGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGR 2940 GL GEK RW+ + E L GD+L+++ ++Y G F +R +W K R Sbjct: 3494 SGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKAR 3553 Query: 2941 DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKW 3000 IP + +L L +A TI WN+ GLP+D SI NGII+ A R+PL+IDPQ+Q W Sbjct: 3554 KIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIW 3613 Query: 3001 IKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG 3060 IKN E N L + L+ + LE+ + G P+L+E+VGEELDP L+ +L + K G Sbjct: 3614 IKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGS 3673 Query: 3061 STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120 + +++GD ++ FR YITTKL NP Y PE S + ++++F +T +G++DQLLG V+ Sbjct: 3674 TFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVIL 3733 Query: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180 E+ +LE+E+ L+ NKR++KE+ED +L L+S++G+++EDE+ I +LS++K A Sbjct: 3734 TEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAE 3793 Query: 3181 EISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFIL 3240 E++QK E++ ETE +I++ R YRP+A SIL+F + ++ + MYQ SL F+ LF L Sbjct: 3794 EVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDL 3853 Query: 3241 SIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKA 3300 S+ S KS I +KR+ + +H TY +Y R L+E+ K LF+ LT+ + + + Sbjct: 3854 SLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHE 3913 Query: 3301 EWRFLLTGGIGLDNPYA--NLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVY 3358 E+ L+ GG LD W+ +W + L L F + + R + WK + Sbjct: 3914 EFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWF 3973 Query: 3359 DSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLA 3418 D P E P ++ + F+R+L+IR PD+ I +++I++ +G + E DL Sbjct: 3974 DKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLE 4033 Query: 3419 KAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLS----SLSLGQGQGPIAMKM 3474 K + +S+ PLI +LS G+DP +++ G +L +S+GQGQ A K+ Sbjct: 4034 KTWEESDPRTPLICLLSMGSDPTDSIIAL-------GKRLKIETRYVSMGQGQEVHARKL 4086 Query: 3475 LEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQ 3534 L++ + G W +LQNCHL +M L + + E H FR+W+T+ FP+++LQ Sbjct: 4087 LQQTMANGGWALLQNCHLGLDFMDELMDII--IETELVHDAFRLWMTTEAHKQFPITLLQ 4144 Query: 3535 NGVKMTNEAPKGLRANIIRSY------LMDPISDPEFFGSCKKPEEFKKLLYGLCFFHAL 3588 +K N+ P+GLRA + R+Y L+D S ++K +LY + F H+ Sbjct: 4145 MSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSG----------SQWKPMLYAVAFLHST 4194 Query: 3589 VQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYE---ELPYEALRYMTGECNYGGR 3645 VQERRKFG LGWNIPYEFN+ D +VQ + L+ + + + +RYM GE YGGR Sbjct: 4195 VQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGR 4254 Query: 3646 VTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAP 3705 VTDD+D+R L + +F+ E + D+ F Y +P +Y++Y ++LP +P Sbjct: 4255 VTDDYDKRLLNTFAKVWFS-ENMFGPDFSFYQG--YNIPKCSTVDNYLQYIQSLPAYDSP 4311 Query: 3706 EIFGMNANADITKDQSETQLLFDNILLTQSR-SAGAGAKSSDEVVNEVASDILGKLPNNF 3764 E+FG++ NADIT + + D IL Q + ++G G ++ + VV +A D+L KLP ++ Sbjct: 4312 EVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDY 4371 Query: 3765 -DIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEV 3823 E R Q MN L QE+ R ++L +R + ++ AI G +MS +L + Sbjct: 4372 VPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDA 4431 Query: 3824 VSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQA 3883 + + + +IP W S+ S LG + + + R W G P FW++GFF Q Sbjct: 4432 LDCMFDARIPAWWKKASWIS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQG 4490 Query: 3884 FLTGAQQNYARK---YTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIK 3940 FLT +Q R + + +L + + PP +GV+++GL+L+GA W+++ Sbjct: 4491 FLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNM 4550 Query: 3941 KLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAM 4000 KL ES PK+L++ +PV+ + + + Y P+YK R + N++ A+ Sbjct: 4551 KLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSCPIYKKPVRTDL--------NYIAAV 4601 Query: 4001 TLPSDQPKEHWIGRGVALLCQL 4022 L + Q EHW+ RGVALLC + Sbjct: 4602 DLRTAQTPEHWVLRGVALLCDV 4623 >gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] Length = 4523 Score = 1909 bits (4946), Expect = 0.0 Identities = 1151/3346 (34%), Positives = 1828/3346 (54%), Gaps = 159/3346 (4%) Query: 726 NGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTE 785 N +L+ +++ Q F Y Q K+ + + L++ + + WT+ Sbjct: 1286 NEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTK 1345 Query: 786 GPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVR---------SKVEDFKQ 836 + +++ +Q++ ++ + + E ++ K+VR V+D Sbjct: 1346 TQWRQIHVEQMDVELRRFAKASSITE--------IWSLNKEVRVWDAYTGLEGTVKDMTA 1397 Query: 837 HIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAAS 896 + I + +P LR RHW + +G ++ +T++ L + L D I + A Sbjct: 1398 SLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAV 1457 Query: 897 KEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFI 956 KE EK + ++ W ++F + TG +L S +++ L+ + ++ QT+ S ++ Sbjct: 1458 KELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYV 1517 Query: 957 KPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDK 1015 + + +Q+ W+ KL + ++ W++VQ TW +LE IF S DI Q+ ++ RRF VD Sbjct: 1518 EYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDA 1577 Query: 1016 TWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLS 1075 ++++M + ++VL + E+LK L L K L EYLE KR+ FPRF+F+S Sbjct: 1578 EFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVS 1637 Query: 1076 NDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKS--SEGEVVELIEIIST 1133 + +LL+ILS+ P +V HL K F+ IA ++F + D++ ++ + E + + Sbjct: 1638 SADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAE 1697 Query: 1134 AKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTK 1193 + G VE WL++LE+ M ++ +A AY + R W+ D+P Q L SQI+WT Sbjct: 1698 CECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTT 1757 Query: 1194 EVQTAIPMGIKALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDV 1249 +V A + E LK ++ Q++ ++TL+ G+L +R + + +DVHARDV Sbjct: 1758 DVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDV 1817 Query: 1250 LSSLV--KKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITP 1305 ++ L+ K+ + F WLSQLR+ W++ H + +A +Y YEYLGNSPRLVITP Sbjct: 1818 VAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITP 1877 Query: 1306 LTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGK 1365 LTDRCY TL +LHL + GAP GPAGTGKTETTKDL +A+ VFNCS+ +DY ++G Sbjct: 1878 LTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGN 1937 Query: 1366 FFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCA 1425 +KGL+ GAW CFDEFNRI +EVLSVVA Q+ I I +F G + L P+ Sbjct: 1938 IYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVG 1997 Query: 1426 VFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATY 1485 +FITMNPGYAGR+ELP+NLKALFR AM+ PD +I EI+L + GFV AR L+ K + Y Sbjct: 1998 IFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLY 2057 Query: 1486 RLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDL 1545 LC E LS Q HYD+G+RA+KSVL AG+LK N E+ +L+R++ D N+PK ++ D+ Sbjct: 2058 TLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDI 2117 Query: 1546 PLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGF 1605 P+F G+ DLFP + +P+ ++ + + LQ F K++Q+ E++ VRH Sbjct: 2118 PVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSV 2177 Query: 1606 MIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHE 1665 +VG GK+ R L ++ +K + + LNPK+VT +L+G + E Sbjct: 2178 FVVGNAGTGKSKILRTLNRTYVNMKQKPVWND-------LNPKAVTTDELFGFIHHATRE 2230 Query: 1666 WSDGVLAVS-FRAFASSVTPDR--------KWLIFDGPVDAVWIENMNTVLDDNKKLCLM 1716 W DG + S F SS+ ++ KW++ DG +D +WIE++NTV+DDNK L L Sbjct: 2231 WKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLA 2290 Query: 1717 SGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSV 1776 S E I ++P M L+FE L A+PATVSR G++Y+ P LGW P + SW++ Sbjct: 2291 SNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWID---RRRHQ 2347 Query: 1777 IQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKER 1836 +K + LFD+ VP ++ +R K ++ +++LV++L L++C + + Sbjct: 2348 SEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLL----TPENVPSD 2403 Query: 1837 NDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTE 1896 + +E Y E F+F+ IW+ G + L++ ISD + S Sbjct: 2404 SPKEVY---EVYFVFACIWAFGGT---------------LLQDQISDYQADF----SRWW 2441 Query: 1897 QTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTI 1956 Q KA V FP +GTI+DY +V K PW K+ + P DV ++V T +T Sbjct: 2442 QKEMKA--VKFPSQGTIFDY-YVDHKTKKLLPWADKIAQFTMDP-DVPLQTVLVHTTETA 2497 Query: 1957 RYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQ 2016 R MELL KP + VG G GK+V++ + L + E Y + F+ TT+ Q Sbjct: 2498 RLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASL--SEDYIVSRVPFNYYTTSTALQ 2555 Query: 2017 NIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLK 2076 I+ L+K+ +GP K+++ F+DD+NMP ++YG P L+RQ +D+ +WYD + Sbjct: 2556 KILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQ 2615 Query: 2077 DCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLE 2136 + ++ + Q + M P G + PR RHF + N S ++ TI+ +I ++H + Sbjct: 2616 KVMLKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQ 2674 Query: 2137 ICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPE 2196 F L ++ T+ ++ M N LPT K HY+FNLRD S V QG+ + PE Sbjct: 2675 -QQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPE 2733 Query: 2197 TTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDN 2256 + + LW+HE RVY D+L+D D ++ + M E ++ F+ + D+ Sbjct: 2734 CLKGPLDLIHLWLHESARVYGDKLIDKKD--------CDLFQRRMLETAYKYFEGI--DS 2783 Query: 2257 DGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLF 2316 +++ + L++C F D + +D +Y + D + L+ I+ L+ YN ++ M+LVLF Sbjct: 2784 HMLLQ----QPLIYCHFAD-RGKDPHYMPVKDWEVLKTILTETLDNYNELN-AAMHLVLF 2837 Query: 2317 RFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEW 2376 A++H+ RISRIL+ P+ ALLVGVGGSG+QS++RLAA++ VFQ+ +++GY E Sbjct: 2838 EDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQEL 2897 Query: 2377 HEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDK 2436 DL + + M VFL TD Q+ +ESFL +++LL +GEIP+LF+ ++ +I Sbjct: 2898 RVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISG 2957 Query: 2437 MRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCC 2496 + + + F+ R QL ++L SP+G R R RKFPA+VNC Sbjct: 2958 IHNEVHALGMVDSREN----CWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCT 3013 Query: 2497 TIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKS-FHTSTIDLSKSFFVELQRY 2555 IDWF +WP++AL +V+ RF+EE + E + I + + HT+ ++S ++ +R+ Sbjct: 3014 AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRH 3073 Query: 2556 NYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQ 2615 NY TP S+LE IS FK LL+KK++EV + K+R G++KL + +SQV ++ L + + Sbjct: 3074 NYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAE 3133 Query: 2616 LKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPI 2675 L++ + + + ++ I ++ +V++ + I A+E + EC+ADL A P Sbjct: 3134 LQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPA 3193 Query: 2676 LESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDF 2735 L +A AAL+TL +++ +K+ +PP V V A+ +L P G K + Sbjct: 3194 LVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLA--------PRGRVPK-DRS 3244 Query: 2736 WGPAKRLLGDM-RFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLC 2794 W AK +G + FLQ+L YDK++IP + ++ ++Y+ +P+F P IR S AA GLC Sbjct: 3245 WKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLC 3304 Query: 2795 KWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLEL 2854 WVI + + +V V PK+ LA A EL A + L + L ++ L+RL + E Sbjct: 3305 AWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEK 3364 Query: 2855 NKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGV 2914 +K + +V+ +K ++ A +L+ L +K RW + L GD+L+++ Sbjct: 3365 ATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAF 3424 Query: 2915 VAYLGAFTSTYRQNQTK-EWTTLCKGR-DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDS 2972 V+Y+G FT YRQ +W + + IP ++ L+ L + TI WN GLPSD Sbjct: 3425 VSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDR 3484 Query: 2973 FSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGT 3032 S +N I+ + RWPL+IDPQ Q KWIKN + L V L + ++ +E + FG Sbjct: 3485 MSTENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETALAFGD 3543 Query: 3033 PVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLP 3092 +L+EN+ E +DP+L+PLL + T K+G IR+GD E+ +FR + TKL NPHY P Sbjct: 3544 VILIENLEETIDPVLDPLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHTKLANPHYKP 3601 Query: 3093 ETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKIL 3152 E + TLLNF +T +G++ QLL VV+ ERPDLE+ K L + K +LK +ED +L Sbjct: 3602 ELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLL 3661 Query: 3153 EVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSI 3212 LS++EG+ L+D ++ L ++K EI K A+E E+KI+ R YRP+A +S+ Sbjct: 3662 LRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASL 3721 Query: 3213 LFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCR 3272 L+F + DL I P+YQ+SL F LF +IE ++K E + R+ IL + T+++++ + Sbjct: 3722 LYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQ 3781 Query: 3273 SLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEIC 3332 +LFEKDKL F + +LL ++ I+ E FLL +++ + + +L +SW I Sbjct: 3782 ALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLR--FTVEHTHLSPVDFLTSQSWSAIK 3839 Query: 3333 RLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDK 3392 + + F+ I R+ W+K +S P E P+EW+ K + Q+++++R +RPD+ Sbjct: 3840 AIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWK-KKSLIQKLILLRAMRPDR 3898 Query: 3393 VIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAAL------LK 3446 + L+ F+ +LG ++E DL KAF +S+ P+ F+LSPG D + L L Sbjct: 3899 MTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLG 3958 Query: 3447 FADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEE 3506 F D G K ++SLGQGQ +A LEKA K G WV+LQN HL W+ TLEK+ E Sbjct: 3959 FTIDSG----KFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLER 4014 Query: 3507 LSPESTHPDFRMWLT--SYPSPN---FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPIS 3561 S + +H D+R++++ S P+P+ P +L+N +K+TNE P G+ AN+ + Sbjct: 4015 FS-QGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYN---F 4070 Query: 3562 DPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMF 3621 D + C K +EFK +L+ LC+FHA V R +FGP GW+ Y FN DL I L+ + Sbjct: 4071 DQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNY 4130 Query: 3622 LNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIY 3681 L ++P+E LRY+ GE YGG +TDDWDR+ R L +F NP L E D + G + Sbjct: 4131 LEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTE--DELMLAPG-F 4187 Query: 3682 FVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAG 3741 PP D+ Y +Y + + +P ++G++ NA+I + LF +L Q R+A +G Sbjct: 4188 AAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSG 4247 Query: 3742 ---AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKT 3798 +S++E V V DIL KLP F++ M++ + V QE R N L++ Sbjct: 4248 DELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQK--NSNRSPYVLVCFQECERMNILIRE 4305 Query: 3799 IRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARL 3858 IR S + ++KG +S +E ++ +P+ W +YPS L + ND L R Sbjct: 4306 IRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRC 4365 Query: 3859 KFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPID--LLGFDYEVMEDKEY 3915 + L W ++ P V WLSGFF Q+FLT Q ARK P+D L D ++Y Sbjct: 4366 RELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDY 4425 Query: 3916 KHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVA 3975 HPP +G ++HGLF++GA W+ + + E+ K L +PV++ K + +Y Sbjct: 4426 GHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYEC 4485 Query: 3976 PLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQ 4021 P+Y+T R +++ L S++ W+ GVALL + Sbjct: 4486 PVYRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522 >gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] Length = 4490 Score = 1900 bits (4923), Expect = 0.0 Identities = 1180/3609 (32%), Positives = 1906/3609 (52%), Gaps = 150/3609 (4%) Query: 469 VDAHKEKIKEVIMKESV------APTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKI 522 V HK+ K V++ S A E L+ + KY L T + V FLA N S +I Sbjct: 976 VAEHKDISKLVLLLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEI 1035 Query: 523 IDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRAL---VKRADIICGKLLAKMFRDH 579 EI Y +EI I +G E+H E + AL K ++ + L + ++ Sbjct: 1036 RSEILHYATFEQEIDELK-PIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKK 1094 Query: 580 QEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFL 639 +E+ + + + + ME + I+ E I+++ L + A L Sbjct: 1095 MSYMIAFINEYLKKLSRPIRDLDDVRFAMEALSCIRDNE----IQMDMTLGPIEEAYAIL 1150 Query: 640 IEY-VNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELES 698 + V + + +++ + ++ ++ + + +++ L E F E++ + Sbjct: 1151 NRFEVEVTKEESEAVDTLRYSFNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVIN 1210 Query: 699 YAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKK 758 +A+ E Q + QI D K +++ E+ FG + Y K Sbjct: 1211 FAEAYELEGPMVPNIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHK 1270 Query: 759 IQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSP 818 + LN +LY S+ + E + V+ +++ A++ + KL K D Sbjct: 1271 TRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQ 1330 Query: 819 YALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS-TVSSFL 877 L + K++ +DF + PL++++ N ++ RHW+ +S + G P DS + + + Sbjct: 1331 AFLDLKKRI----DDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIM 1386 Query: 878 DMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVD--E 935 + L + D E I +A KE +E + ++I W +++ G +L + E Sbjct: 1387 EAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGE 1446 Query: 936 IQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFS 995 I L++D ++ ++ + + P++K ++ W KL +I++EWL VQ W+YLE +F Sbjct: 1447 IITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFV 1506 Query: 996 SPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRML-ERLKKSNELLELIL 1054 DI Q+P+E +RF +DK+W IM+ ++ +V+ D + + L +E LE+ Sbjct: 1507 GGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQ 1566 Query: 1055 KGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDI 1114 K L YLEKKRL FPRFFF+S+ LLEIL + D +QPHL + I +V F D Sbjct: 1567 KSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTF-HAKDY 1625 Query: 1115 THMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTK--YERI 1172 + + E I + ++ A+G VE WL++L ++ ++S+H + A + + ++ + Sbjct: 1626 DRIMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLL 1685 Query: 1173 NWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGK----L 1228 ++ +P Q L Q+ WT + + A+ K + ++ N++ DI+ + + L Sbjct: 1686 PFLSHFPAQVGLLGIQMLWTHDSEEAL-RNAKDDRKIMQVTNQKFLDILNTLISQTTHDL 1744 Query: 1229 SMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLET--KMINA 1286 S +RV L+ + VH RD+ LVK +I +DFEWL Q R+Y++E+ +T + + Sbjct: 1745 SKFDRVKFETLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDV 1804 Query: 1287 GLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVA 1346 Y E+LG + RLVITPLTDRCY TL AL +++GGAP GPAGTGKTETTKD+ + + Sbjct: 1805 DFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLG 1864 Query: 1347 KQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINA 1406 K VVFNCSD +D+ LG+ FKGL G+W CFDEFNRI+L VLSV AQQI + Sbjct: 1865 KYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKE 1924 Query: 1407 GADILMF-EGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIV 1465 +F +G + L+P +F+TMNPGYAGR ELP+NLK FRTVAMMVPD +I + Sbjct: 1925 RKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVK 1984 Query: 1466 LYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEE 1525 L SCGF+ L+ K Y+LC EQL+ Q HYD+G+R + SVL G+ K P ++E Sbjct: 1985 LASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044 Query: 1526 ILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMT 1585 +++R + D+NL K + D PLF + +DLFPG++L Y +L A+ L Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINH 2104 Query: 1586 AFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVL 1645 ++ K++Q+YE +VRHG M +G GKT+ +L A + C + E + Sbjct: 2105 PPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTE-CGRPHREMR------M 2157 Query: 1646 NPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNT 1705 NPK++T Q++G+ D+ +++W+DG+ + +R + + +LI DGPVDA+WIEN+N+ Sbjct: 2158 NPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNS 2217 Query: 1706 VLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLS 1765 VLDDNK L L +G+ I M+P L+FE ++E ASPATVSR GM+Y+ L WRP++ + Sbjct: 2218 VLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQA 2277 Query: 1766 WVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMD 1825 W+ A + + + L++++ + +++ + + N + +NL++ + Sbjct: 2278 WLKKRTAQEAAV----FLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIP 2333 Query: 1826 DFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRT 1885 KE L +F+F L+WS+GA + R K LR+ + Sbjct: 2334 S-------KEEGGVSCVEHLHKLFVFGLMWSLGALLELESREKLEAFLRQ------HESK 2380 Query: 1886 RNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAP-PIPKDVM 1944 + ++ G+ QT Y+F G WE W KKL+ P Sbjct: 2381 LDLPEIPKGSNQTM----------------YEFYVTDYGDWEHWNKKLQPYYYPTDSIPE 2424 Query: 1945 FNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLI 2004 ++ I+VP +D IR + L++ + K + G GT K+V + +L + + E+ + Sbjct: 2425 YSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSL 2483 Query: 2005 NFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLR 2064 NFS+ T Q + S +DKR +GPP G++M VF+DD+NMP +G Q E++R Sbjct: 2484 NFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVR 2543 Query: 2065 QWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSM 2123 Q ++ Y L K +VD+Q++ AM PGGGRN + R R F + S+ S+ Sbjct: 2544 QMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASI 2603 Query: 2124 YTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDF 2183 IF I + + C F + ++ +V+ L++ +LPTP+K HY+FNLRD Sbjct: 2604 DKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDL 2663 Query: 2184 SRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYE 2243 SR+ QG+ + E + + L+ HE RV DR + D W ++ + + Sbjct: 2664 SRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGS 2723 Query: 2244 DFHELFQRLDFDNDGMVEADDLRSLMFCD--FHDPKREDTNYREIADVDNLRMIVEIHLE 2301 D + D + E + D F PK Y + D L ++ + Sbjct: 2724 DAASCILPEPYFVDFLREMPEPTGDEPEDSVFEVPKI----YELMPSFDFLAEKLQFYQR 2779 Query: 2302 EYNNISK-KPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADY 2360 ++N I + ++LV F+ A+ H+ +ISRI++ +ALLVGVGGSG+QS++RLA+ +A Y Sbjct: 2780 QFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGY 2839 Query: 2361 SVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGV-FLFTDTQIKEESFLEDVSNLLNAG 2419 +FQ+ +++ Y+ T +DLK L K A + +G+ F+FTD++IK+E+FLE ++NLL++G Sbjct: 2840 QIFQITLTRSYNVTNLTDDLKA-LYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSG 2898 Query: 2420 EIPNLFALDEKQEICDKMRQ-LDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPI 2478 EI NLFA DE EI + + R+ + T + L+ FI R LHVVL SP+ Sbjct: 2899 EISNLFARDEMDEITQGLISVMKRELPRHPPTFDN---LYEYFISRSRKNLHVVLCFSPV 2955 Query: 2479 GDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEE--IEMSEEIRDGCIDMCKS 2536 G+ FR R KFP L++ CT+DWF WP +AL AVAS FL + I S EI+ ++ Sbjct: 2956 GEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGL 3015 Query: 2537 FHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLD 2596 FH + +S+F +R +VTP SYL I+ +K + +K + + +R +GL+KL Sbjct: 3016 FHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLM 3075 Query: 2597 SASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAM 2656 AS VA + +L +L VAS + DE++ + + AK + V+ + A + Sbjct: 3076 EASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVD 3135 Query: 2657 ASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKG 2716 + K + ++ L A P LE A AAL+T+ DI V+ + PP + +M+ + +L Sbjct: 3136 EIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQ 3195 Query: 2717 IKADKIP-DPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPN 2775 K D + DP S K WG + +L+ FL SL ++ KD I + +++ Y Sbjct: 3196 KKIDPVTMDPEKSCCKPS--WGESLKLMSATGFLWSLQQFPKDTINEETVELLQP-YFNM 3252 Query: 2776 PDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQ 2835 D+ E + GL W +AM + + + V P K LA EG L +A L K Q Sbjct: 3253 DDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQ 3312 Query: 2836 AALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTAL 2895 A L E Q +L ++Q + +K DL N D C KK++ A LI GL GEK RW+ + Sbjct: 3313 ALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSK 3372 Query: 2896 ELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKE-WTTLCKGRDIPCSDDCSLMGTL 2954 E L GDIL+ +G ++YLG F +R K+ W + R IP +++ +L+ L Sbjct: 3373 EFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISML 3432 Query: 2955 GEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIK 3014 + TI W + GLP D SI NGII+ A R+PL+IDPQ+Q WIK+ EK N L V Sbjct: 3433 VDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTS 3492 Query: 3015 LSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYA 3074 L+ + LE+ + G P+L+E++ EELDP L+ +L K K G + +++GD + Sbjct: 3493 LNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIM 3552 Query: 3075 PDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALI 3134 F+ YITTKL NP + PE + K ++++F +T +G+++QLL V+ E+ +LE E+ L+ Sbjct: 3553 DTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLL 3612 Query: 3135 LQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEK 3194 NKR++KE+ED +L LS+++G++++DE+ I +L ++K A E+S+K VA ETE Sbjct: 3613 EDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEI 3672 Query: 3195 KIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKR 3254 KI+ + +RP A SIL+F + +++ + MYQ SL F+ LF S+ SEKS + KR Sbjct: 3673 KINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKR 3732 Query: 3255 LQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLD- 3313 + + ++ TY ++ R L+E K LF +T+ + L + E++ L+ GG LD Sbjct: 3733 ITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDL 3792 Query: 3314 -----NPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVF 3368 PY W+ +W + L LP F I + R + GWK +D P E+ Sbjct: 3793 KACPPKPY----RWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEII 3848 Query: 3369 PEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCA 3428 P+ + D + ++L+IR PD+ + +++I + L + EP +L K + +S+ Sbjct: 3849 PDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRT 3908 Query: 3429 PLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQ 3488 PLI LS G+DP + A + ++S+GQGQ A K+++ ++++G WV+LQ Sbjct: 3909 PLICFLSMGSDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQ 3965 Query: 3489 NCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLR 3548 NCHL +M L + ++ E++ FR+W+T+ P FP+++LQ +K TNE P+G+R Sbjct: 3966 NCHLGLEFMEELLETL--ITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVR 4023 Query: 3549 ANIIRSY------LMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNI 3602 A + R++ L+D + P +K +LY + F H+ VQERRKFGPLGWNI Sbjct: 4024 AGLKRTFAGINQDLLDISNLP----------MWKPMLYTVAFLHSTVQERRKFGPLGWNI 4073 Query: 3603 PYEFNETDLRISVQQLHMFLNQYE---ELPYEALRYMTGECNYGGRVTDDWDRRTLRSIL 3659 PYEFN D SVQ + L++ + + + +RYM GE YGGRVTDD+D+R L Sbjct: 4074 PYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFA 4133 Query: 3660 NKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKD 3719 +F+ ++ E S + Y +P Y EY ++LP PE+FG++ NADIT Sbjct: 4134 RVWFSEKMFEPSFCFYTG---YKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQ 4190 Query: 3720 QSETQLLFDNILLTQSRSAGAG-AKSSDEVVNEVASDILGKLPNNF-DIEAAMRRYPTTY 3777 + + + I Q + +G G ++ + +V ++ D+L KLP ++ E R + Sbjct: 4191 SNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGH 4250 Query: 3778 TQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWM 3837 SMN L QE+ R +++ +R S +++ AI+G +MS +L + + ++ + +IP++W Sbjct: 4251 LNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWK 4310 Query: 3838 GKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYT 3897 S+ S LG + + L R W G P VFW++GFF Q FLT +Q R + Sbjct: 4311 RVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHK 4369 Query: 3898 -IPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTV 3954 +D + EV+ +E PP +GV+I+GL++DGA+W+R+ KL ES PK+L+ + Sbjct: 4370 GWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQL 4429 Query: 3955 PVMWLKPCKRADIPKRPS-YVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIG 4013 PV+ + + PK P YV P+YK R + F+ + L + +HWI Sbjct: 4430 PVLHIFAI-NSTAPKDPKLYVCPIYKKPRRTDL--------TFITVVYLRTVLSPDHWIL 4480 Query: 4014 RGVALLCQL 4022 RGVALLC + Sbjct: 4481 RGVALLCDI 4489 >gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] Length = 4646 Score = 1308 bits (3385), Expect = 0.0 Identities = 938/3431 (27%), Positives = 1627/3431 (47%), Gaps = 329/3431 (9%) Query: 785 EGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVI 844 E P+ V P ++ ++ L K+F A + V+ ++ + + L+ + Sbjct: 1348 EQPWVSVQPRKLRQNLD----ALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIEL 1403 Query: 845 CNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKA 904 + L+ RHW+ + + S+ T+ D++L+ + + A E +LE+ Sbjct: 1404 KSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEF 1462 Query: 905 MEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMR 964 ++++ W+ E + +Y+ I D++ + +HI M+ SP+ K +E+ Sbjct: 1463 LKQIREVWNTYELDLVNYQNKCRLI-RGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDAL 1521 Query: 965 EWEGKLLLLQEILDEWLKVQATWLYLEPIFS-SPDIMSQMPEEGRRFTAVDKTWRDIMRS 1023 WE KL + + D W+ VQ W+YLE IF+ S DI +P E +RF ++ + +M+ Sbjct: 1522 SWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKK 1581 Query: 1024 VMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEIL 1083 V + V+ V+ I + L++ +LL I K L EYLE++R FPRF+F+ +++LLEI+ Sbjct: 1582 VSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEII 1641 Query: 1084 SETKDPTRVQPHLKKCFEGIAKVEFTETLDIT-HMKSSEGEVVELIEIISTAKARGQVEK 1142 +K+ ++Q H KK F G++ + E + + S EGE V +S + ++ + Sbjct: 1642 GNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINE 1700 Query: 1143 WLVELERVMINSIHKVTGDATFAYTKYER---------INWVRDWPGQTVLCVSQIFWTK 1193 WL +E+ M ++ K+ ++ + + I W+ + Q V+ +QI W++ Sbjct: 1701 WLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSE 1760 Query: 1194 EVQTAIP-MGIKALEQYLKTCNRQIDDIVTLVRGKLSMQN----RVTLGALVVLDVHARD 1248 V+TA+ MG L + ++ + ++ + M+ R L L+ VH RD Sbjct: 1761 NVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRD 1820 Query: 1249 VLSSLVKKNISDDSDFEWLSQLRYYWQENH------LETKMINAGLRYGYEYLGNSPRLV 1302 V SL+K I + FEWLSQ+R+Y+ L +M NA YG+EYLG +LV Sbjct: 1821 VTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLV 1880 Query: 1303 ITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLA 1362 TPLTDRCY T+ AL LGG+P GPAGTGKTE+ K L + + +VFNC + D+ A Sbjct: 1881 QTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQA 1940 Query: 1363 LGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGAD----------ILM 1412 +G+ F GL GAW CFDEFNR++ +LS V+QQ+ IQ + ++ Sbjct: 1941 MGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCE 2000 Query: 1413 FEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFV 1472 ++K+ P A+FITMNPGYAGRS LPDNLK LFR++AM PD +IA+++LYS GF Sbjct: 2001 LLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFR 2060 Query: 1473 TARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL----KYPNENEEI-- 1526 TA L+ KIV ++LC EQLSSQ HYD+G+RA+KSVL +AGN+K K E EE Sbjct: 2061 TAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGE 2120 Query: 1527 ---------------LLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLA 1571 +L++S+ + +PK ++ D+PL + SD+FPGV+ + + L Sbjct: 2121 AVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALRE 2180 Query: 1572 AIKDNCASMNL------QMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGA 1625 +K C M L ++ + EK+LQ+Y++ + HG M+VG GK+ A+RVL A Sbjct: 2181 ELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKA 2240 Query: 1626 LNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPD 1685 L + E + +++PK+++ LYG D + EW+DG+ R SV + Sbjct: 2241 LERL------EGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGE 2294 Query: 1686 ---RKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPA 1742 R+W++FDG VD W+EN+N+VLDDNK L L +GE + + P + ++FE DL+ A+ A Sbjct: 2295 LQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLA 2354 Query: 1743 TVSRCGMIYMEPHMLGWRPLMLSWVNLL------------------------PASVSVIQ 1778 TVSRCGM++ +L + +++ L A+ ++Q Sbjct: 2355 TVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQ 2414 Query: 1779 KEFIMGLFDRMVPVSVEFIRK---HTKELSPTSDTNLVRSLMNLIDCFMD---------- 1825 + + S + K H +L D +R L +L Sbjct: 2415 IQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNA 2474 Query: 1826 ---DFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPIS 1882 DF +++ ER ++ +++++WS+ D RLK L E + Sbjct: 2475 NHPDFPMQIEQLER-------YIQRYLVYAILWSLSG----DSRLKMRAELGEYIR---- 2519 Query: 1883 DRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKD 1942 + TVP P I + G+W PW K+ + Sbjct: 2520 ------------------RITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHK 2561 Query: 1943 VMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPL 2002 V +++VPTLDT+R+ AL+ KP + GP G+GK++ + + L + E+ + Sbjct: 2562 VAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEV---V 2618 Query: 2003 LINFSAQTTAAQTQNIVMSKLDKRR--KGVFGPP--LGKRMVVFVDDVNMPAREVYGAQP 2058 +NFS+ TT + RR GV P LGK +V+F D++N+P + YG Q Sbjct: 2619 GLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQR 2678 Query: 2059 PIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPP-GGGRNPVTPRYMRHFNIITINE 2117 I +RQ ++H +Y D + +KL IQ + A PP GR P++ R++RH ++ ++ Sbjct: 2679 VISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDY 2738 Query: 2118 FSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYL 2177 S+ I+ T++ + P L + + M + + + HY+ Sbjct: 2739 PGPASLTQIYG---TFNRAMLRLIPS--LRTYAEPLTAAMVEFYTMSQERFTQDTQPHYI 2793 Query: 2178 FNLRDFSRVIQGVCLS-RPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEI 2236 ++ R+ +R ++G+ + RP T E + R+W HE LR++ DRL+++ +R W I + Sbjct: 2794 YSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTV 2853 Query: 2237 LRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIV 2296 + F +D E R +++ ++ + E+ D R+ Sbjct: 2854 ALKH--------FPNID------REKAMSRPILYSNWLSKDYIPVDQEELRDYVKARL-- 2897 Query: 2297 EIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAH 2356 ++ EE ++ LVLF ++H+ RI RI +QP+ H LL+GV G+G+ +++R A Sbjct: 2898 KVFYEEELDVP-----LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAW 2952 Query: 2357 MADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLL 2416 M SV+Q+++ + Y ++ EDL+ +LR+ + F+ ++ + + FLE ++ LL Sbjct: 2953 MNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLL 3012 Query: 2417 NAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMS 2476 GE+P LF E E M Q K S L+ F LHVV M+ Sbjct: 3013 ANGEVPGLF---EGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMN 3069 Query: 2477 PIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMS------------- 2523 P + ++R PAL N C ++WF W +AL V F ++++ Sbjct: 3070 PSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVV 3129 Query: 2524 -----------EEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKL 2572 E I + C+ + ++ H + L+K R +TP YL+ I+ + Sbjct: 3130 YDKLPQPPSHREAIVNSCVFVHQTLHQANARLAK----RGGRTMAITPRHYLDFINHYAN 3185 Query: 2573 LLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEK 2632 L +KRSE+ + + VGL K+ QV ++ +L +L+V + ++ + + K Sbjct: 3186 LFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVK 3245 Query: 2633 ESVEVAK--------TEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALD 2684 + E K E++ K E IA++Q + DL P + A A+ Sbjct: 3246 DQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKE--------DLDKVEPAVIEAQNAVK 3297 Query: 2685 TLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLG 2744 ++ Q + V+SM +PPA VKL +E+IC+L G W + ++ Sbjct: 3298 SIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTD--------------WKQIRSIIM 3343 Query: 2745 DMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804 F+ ++ + + I A ++KNY+ NP + E + AS A + KW IA +Y Sbjct: 3344 RENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYA 3403 Query: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864 + K V P + +L E + K + + +++++ +AR ++ + + ++ Sbjct: 3404 DMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKA 3463 Query: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924 + K+ R+ L+ L E+ RW T+ + GD L+S+ +AY G F Sbjct: 3464 DLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQ 3523 Query: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984 RQN W+ + +I D + L A W + LP+D +N I++ Sbjct: 3524 MRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRF 3583 Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044 R+PL+IDP QA ++I N K + + + + LE+ ++FG P+L+++V E D Sbjct: 3584 NRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYD 3642 Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104 P+L P+L ++ + GG I LGD I+ +P F +++T+ + P+ +VT +NF Sbjct: 3643 PVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFT 3702 Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164 +T +Q Q L V+ ERPD++E++ L+ E + +L+++E +L+ L+ +G IL+ Sbjct: 3703 VTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILD 3762 Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224 D+T I L + K A E+++K E + ++++T Y P++ S ++F++ L I Sbjct: 3763 DDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIH 3822 Query: 3225 PMYQYSLTWFINLF-ILSIENSEKSEIL--AKRLQILKDHFTYSLYVNVCRSLFEKDKLL 3281 +YQYSL +F++++ + EN + +RL I+ + V R + +D + Sbjct: 3823 FLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHIT 3882 Query: 3282 FSFCLT---INLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLP 3338 F+ L + + E + FL I L L + + + RL LP Sbjct: 3883 FAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLP 3942 Query: 3339 AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDK------ANEFQRMLIIRCLRPDK 3392 AFK + + ++ + + DS P V P W ++ R+L+I+ RPD+ Sbjct: 3943 AFKDLIAK-VQADEQFGIWLDSSSPEQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDR 4000 Query: 3393 VIPMLQEFIINRLGRAF--IEPPPFDLAKAFG-DSNCCAPLIFVLSPGADPMAALLKFAD 3449 ++ M F+ LG +F I P DL G + P++ PG D + A Sbjct: 4001 LLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAA 4060 Query: 3450 DQGYGGSKLSSLSLGQGQG-PIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELS 3508 +Q ++++S+++G +G A K + AVK G WV+L+N HLA W+ LEK L Sbjct: 4061 EQ---NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQ 4117 Query: 3509 PESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGS 3568 P H FR++LT +P PV++L+ G E P G++AN++R++ P+S Sbjct: 4118 P---HACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVS-----RI 4169 Query: 3569 CKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQY--- 3625 CK P E +L + L +FHA++QER ++ PLGW+ YEF E+DLR + + +L+ Sbjct: 4170 CKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKG 4229 Query: 3626 ------EELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENS---DYKFD 3676 +++P+ AL+ + + YGGRV +++D+R L + L + F ++ K D Sbjct: 4230 RQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVD 4289 Query: 3677 SSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANA----------DITKDQSETQLL 3726 +P + ++++ + LP T P G+ NA D+ + Q+L Sbjct: 4290 GHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQML 4349 Query: 3727 FDNILL--------TQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYT 3778 D L T++ S G + ++ AS+ L +P + ++R Sbjct: 4350 EDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTL---SHLKRTVENIK 4406 Query: 3779 QSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMG 3838 + +E+ KLL+ +R ++ + +G + L +++ ++ +P W Sbjct: 4407 DPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSH 4466 Query: 3839 KSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPP--------VFWLSGFFFTQAFLTGAQQ 3890 + P+ + +V+DF R+K LQ L G F +A++T +Q Sbjct: 4467 YTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQ 4526 Query: 3891 NYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKIL 3950 A+ + ++ L + V + + GL L GA+ N L+ + + Sbjct: 4527 YVAQANSWSLEELCLEVNV-TTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNA----I 4581 Query: 3951 YDTVPVMWLKPCKRADIPKRPSYVA-PLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKE 4009 +P+ L+ K+ + K+ S V P+Y R ++ F + + + + Sbjct: 4582 STALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLI--------FTVDFEIATKEDPR 4633 Query: 4010 HWIGRGVALLC 4020 + RGVA+LC Sbjct: 4634 SFYERGVAVLC 4644 >gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] Length = 4314 Score = 1268 bits (3282), Expect = 0.0 Identities = 963/3475 (27%), Positives = 1667/3475 (47%), Gaps = 308/3475 (8%) Query: 666 IFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRY------- 718 + E H+ +IK++IE + +K R + + +ELE + + ++ D+ + ++ Sbjct: 1021 MMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSA 1080 Query: 719 --LKKAQILNGKLDLAADKI----EQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYET 772 +K+ +I L++ K+ F EE F S+ E+ Sbjct: 1081 KLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKD--------------IES 1126 Query: 773 AVEFSSNYRAWTEGPYHKVNPDQV---------EADIGNYWRGLYKLEKTFHDSPYALAM 823 + + Y + +G N D + E + N+ L K+E+ H M Sbjct: 1127 CAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEE--HS-----VM 1179 Query: 824 TKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEP 883 T K++S+V+ +K IP+++ + L P HW + ++G P S + + L + Sbjct: 1180 TVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADT 1239 Query: 884 YIDR---FEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLL 940 + + + ++ A E ++ +A+ ++ F + Y ++ + + + + + ++ Sbjct: 1240 IVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIV 1299 Query: 941 D---DHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSP 997 + D+ Q+++ SP+ K +E ++ WE KL L E L +Q W+YLEPIF Sbjct: 1300 NQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGR- 1358 Query: 998 DIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGL 1057 +P+E RF VD+ +R IM + +D V T+ T + L + L+ K L Sbjct: 1359 ---GALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSL 1415 Query: 1058 NEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTE-TLDITH 1116 NE+LE+KR FPRF+F+ +D+LLEIL ++ +P+ +Q HLKK F GI V F E + IT Sbjct: 1416 NEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITA 1475 Query: 1117 MKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVR 1176 MKS EGEVV + + VE WL +L M ++ ++ + + Sbjct: 1476 MKSLEGEVVPFKNKVPLSN---NVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPS 1532 Query: 1177 DWPGQTVLCVSQIFWTKEVQTAIP---------MGIKALEQYLKTCNRQIDDIVTLVRGK 1227 +P Q + QI +T++V+ AI + LEQY + +D G Sbjct: 1533 LFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNI-DTSSEDPGNTESGI 1591 Query: 1228 LSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLE-TKMINA 1286 L ++ L AL++ +H DV+ L + + D+ W QLR+Y + +H +M+++ Sbjct: 1592 LELK----LKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCCVQMVDS 1647 Query: 1287 GLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVA 1346 +Y YEY GN+ +LV TPLTD+CY TL A+ + LGG P GPAGTGKTE+ K L + Sbjct: 1648 EFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLG 1707 Query: 1347 KQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINA 1406 +Q +VFNC +G+D ++G+ F GL+ CGAW CFDEFNR++ VLS V+ QI TIQ + Sbjct: 1708 RQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKN 1767 Query: 1407 GADILMFEGTELKLDPTCAVFITMNP---GYAGRSELPDNLKALFRTVAMMVPDYAMIAE 1463 + G E++++ +FITMNP GY GR +LPDNLK LFR VAM PD +IAE Sbjct: 1768 HRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAE 1827 Query: 1464 IVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY---- 1519 ++LYS GF A+ LS K+VA + L E L+ Q HYD+G+RA+K+VL +GNL + Sbjct: 1828 VILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSG 1887 Query: 1520 --PNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNC 1577 N NE ++++++ + KF D F+ + D+FPG++L + +Y++L AA+K Sbjct: 1888 TTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVF 1947 Query: 1578 ASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEE 1637 N ++ +K L++YE + R G +IVG GK++ +R+L AL C+ G + Sbjct: 1948 EEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAAL---CKTGKV-- 2002 Query: 1638 NKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDA 1697 V+ +NPK++ QL G D + EWSDGVL S R W+I DG +D Sbjct: 2003 --VKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDP 2060 Query: 1698 VWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHML 1757 WIE++N+VLDDN+ L + SGE IQ P +N +FE DL ASPAT+SR GMI++ Sbjct: 2061 EWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEET 2120 Query: 1758 GWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLM 1817 L+ SW+ PA + +I F++ +++++ K + TS LV ++M Sbjct: 2121 DLNSLIKSWLRNQPAEYRNNLENWIGDYFEK----ALQWVLKQNDYVVETS---LVGTVM 2173 Query: 1818 NLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNK-ILREL 1876 N + L D + F+ +LI +G + RL+F K + Sbjct: 2174 NGLS----------HLHGCRDHDE-------FIINLIRGLGGNLNMKSRLEFTKEVFHWA 2216 Query: 1877 MESPIS---------DRTRN---TFKLQSGTEQTS---SKALTVPFPEKGTIYDYQFVTE 1921 ESP D TR T+ L+ + T+ S LT+P + + Sbjct: 2217 RESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLP------VIQTPDMQR 2270 Query: 1922 GIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTG 1981 G+ ++PW+ DT ++P I VGP G G Sbjct: 2271 GLDYFKPWLSS---------------------DT-------------KQPFILVGPEGCG 2296 Query: 1982 KSVYITNFLLNQLNKEIYKPLLINFSAQTTA-------AQTQNIVMSKLDKRRKGVFGPP 2034 K + + + +QL + ++ SAQTT+ +QT ++ + + V+ P Sbjct: 2297 KGMLL-RYAFSQLRST--QIATVHCSAQTTSRHLLQKLSQTCMVISTNTGR----VYRPK 2349 Query: 2035 LGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGP 2094 +R+V+++ D+N+P + +G + L+Q L + +YD ++ + L +IQI+ +M Sbjct: 2350 DCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD-ENLEWVGLENIQIVASMSA 2408 Query: 2095 PGG-GRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTT-QI 2152 G GR+ +T R+ + +I+ + + TI+ L L K + + + Sbjct: 2409 GGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYL 2468 Query: 2153 VNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVC---LSRPETTETTEVIKRLWV 2209 + G+M E ++ SHY F ++ + G+ L + + + + Sbjct: 2469 LAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVA 2528 Query: 2210 HEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLM 2269 +E R++ D+++ + ++ IL + D+ LD +D R Sbjct: 2529 YEARRLFRDKIVGAKE----LHLFDIILTSVFQGDWGS--DILDNMSDSFYVTWGARHNS 2582 Query: 2270 FCDFHDPKREDTNYREIADVDN--LRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRIS 2327 + + + + +++ L+ +++ L Y ++ ++++LF +E++SRI Sbjct: 2583 GARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQN-LDILLFHEVLEYMSRID 2641 Query: 2328 RILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKC 2387 R+L P LL G G GR+++T L +HM +F +IS+GY+ ++ DLK +L+ Sbjct: 2642 RVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLA 2701 Query: 2388 AEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKT 2447 Q V L D Q +FLE +++LL++GE+P L+ L+E + + ++ D+ Sbjct: 2702 GIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLK------DQA 2755 Query: 2448 KQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPED 2507 Q DG +FN F + LH+VL M F PAL C + W + W Sbjct: 2756 SQ-DGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNS 2814 Query: 2508 ALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFV--ELQRYNYVTPTSYLE 2565 +++ + E E+ D K ++ D KSF + E + TP+ Y+ Sbjct: 2815 SMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMT 2874 Query: 2566 LISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDE 2625 + + + K+ E++K + + G+ KL+ A + V + + LK E D Sbjct: 2875 FLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADA 2934 Query: 2626 --MMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAAL 2683 MI + + KTE + + IA E+ + + K++ D +L P++ A A+ Sbjct: 2935 ALQMITVSMQDASEQKTE-LERLKHRIA-EEVVKIEERKNKIDDELKEVQPLVNEAKLAV 2992 Query: 2684 DTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLL 2743 + + ++ ++S++ PP ++ ++E + L GI + W K L Sbjct: 2993 GNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGI--------------FDTSWVSMKSFL 3038 Query: 2744 GDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNP-DFVPEKIRNASTAAEGLCKWVIAMDS 2802 + + +D NI + + N F P+ + ASTAA L WV A Sbjct: 3039 AKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQ 3098 Query: 2803 YDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADL 2862 Y V + + P + + A E LK D RK + L V K++ L++ + + A L Sbjct: 3099 YSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKL 3158 Query: 2863 ENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFT 2922 E +V + ++ AE LI L E RW+ +E+ + L +++ + YL A Sbjct: 3159 EAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAP 3218 Query: 2923 STYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIM 2982 + R+ +EWT K + D + T E + W GLPSD SI+N ++I+ Sbjct: 3219 ESLRKTCLEEWT---KSAGLEKFDLRRFLCTESEQLI---WKSEGLPSDDLSIENALVIL 3272 Query: 2983 N-------ARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVL 3035 +R P +IDP SQA +W+K K + L VI + +++ LE ++FG ++ Sbjct: 3273 QIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLI 3332 Query: 3036 LENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETS 3095 ++ + + ++P+L PLL + QG +++GD I+Y +FR +++T+ NP P+ + Sbjct: 3333 IQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAA 3391 Query: 3096 VKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVL 3155 VT +NF T G++ QLL + + E+PDLEE+K L+ Q + K QL ++E+ +LE L Sbjct: 3392 SIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETL 3451 Query: 3156 SSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFF 3215 ++S+GNILE++ I+ L+ +KA + I + + + + + +D R Y P+A +S ++F Sbjct: 3452 ATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYF 3511 Query: 3216 SLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLF 3275 ++DL+ I MY++SL F+ LF +++N + SE +R+Q L + +Y +CR LF Sbjct: 3512 IISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLF 3571 Query: 3276 EKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIG-----LDNPYA---NLCTWLPQ-K 3326 + D+L+F+ +H + EW +G D+ L +W+ Q + Sbjct: 3572 KADQLMFALHFVRG--MHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQER 3629 Query: 3327 SWDEICRLDDLPA-FKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLII 3385 SW LP+ ++T+ E L W+ Y++ E FP K + FQ++L++ Sbjct: 3630 SWAVATLKIALPSLYQTLCFEDAAL---WRTYYNNSMCEQE-FPSILAKKVSLFQQILVV 3685 Query: 3386 RCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALL 3445 + LRPD++ + F LG + P P +L + + ++ P++ ++SPGADP L Sbjct: 3686 QALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQ 3745 Query: 3446 KFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCE 3505 + A+ + G +++GQGQ +A++ML++ + G W+ L+N HL SW+P LEK Sbjct: 3746 ELANAE-RSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELN 3804 Query: 3506 ELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEF 3565 L P+ T FR+WLT+ PNF +LQ+ +K+T E+P GL+ N++R+Y PE Sbjct: 3805 TLQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTY---ESWTPEQ 3858 Query: 3566 FGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQY 3625 S K L+ L +FHA QERR + P GW YEF+ +DLR + + Sbjct: 3859 I-SKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA 3917 Query: 3626 EELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYF--- 3682 +++ +E + + YGGR+ + +D R L+S L +FFN +++ + + S + Sbjct: 3918 KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVS 3977 Query: 3683 VPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGA 3742 +P S Y + +P P FG+ AN + + + + + + RS AG+ Sbjct: 3978 LPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRIL-GRSITAGS 4036 Query: 3743 KSSDEVVNEVASDILG---KLPNNFDIEAAMRRYPTTYTQSMNTVL---VQEMGRFNKLL 3796 K E+ + S +L KL N ++ ++ P + + +L + E +L+ Sbjct: 4037 KFDREIWSNELSPVLNLWKKLNQNSNL--IHQKVPPPNDRQGSPILSFIILEQFNAIRLV 4094 Query: 3797 KTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLA 3856 +++ S + K I+G ++S++++++ S++LN K P W K PL Y+ +A Sbjct: 4095 QSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPL-QYLRGLVA 4153 Query: 3857 RLKFLQQWYEVGPPPVFW-----LSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVME 3911 R +Q W + LS F FL +Q AR +D L F V Sbjct: 4154 RALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF---VAS 4210 Query: 3912 DKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPK-- 3969 K + + I GL L+G S++ +L+E+ D+ V + PC IP+ Sbjct: 4211 WKGRLQEAKLQIKISGLLLEGCSFDG--NQLSENQ----LDSPSVSSVLPCFMGWIPQDA 4264 Query: 3970 ------RPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVAL 4018 P+Y ++ER V++ + +P ++ WI G AL Sbjct: 4265 CGPYSPDECISLPVYTSAERDRVVTN----------IDVPCGGNQDQWIQCGAAL 4309 >gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo sapiens] Length = 4515 Score = 937 bits (2421), Expect = 0.0 Identities = 594/1892 (31%), Positives = 955/1892 (50%), Gaps = 227/1892 (11%) Query: 2328 RILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKC 2387 R+L + + +G+ G G+++ LA ++ D +++V IS E+ E K + Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712 Query: 2388 AEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKT 2447 V + + I+++SFLED++ ++++G IP+LF E I K+R L Q Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772 Query: 2448 KQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPED 2507 +L + F LH+ + MSP G +FR R +P++++ CTIDW++ WPE+ Sbjct: 2773 DNRQ----SLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEE 2828 Query: 2508 ALQAVASRFLEE---IEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYL 2564 AL VA+ FL+E E E +++ C H S DL++ +F E R+ Y TP SYL Sbjct: 2829 ALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYL 2888 Query: 2565 ELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVD 2624 + + TF +L + E+ + R+ +GL + A++ V MQ EL L PQ++ +KE + Sbjct: 2889 QFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETE 2948 Query: 2625 EMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALD 2684 +M + K+S V K + +VK DE I E+ + + +L LP + A+ AL+ Sbjct: 2949 TLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALN 3008 Query: 2685 TLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLG 2744 L D+ ++ PP V VM A+CIL K + W AK LL Sbjct: 3009 ALDKADVAELRVYTRPPFLVLTVMNAVCILLQKKPN---------------WATAKLLLS 3053 Query: 2745 DMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYD 2804 + FL+ L DKD+IP ++K + PDF P KI S A LC+WVIA+++Y Sbjct: 3054 ETGFLKKLINLDKDSIPDKVFVKLKK-IVTLPDFNPHKISLVSVACCSLCQWVIALNNYH 3112 Query: 2805 KVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLEN 2864 +V K+V PK+I++A A+ LKIA L +KQ L+ V++ L LQ + +K L N Sbjct: 3113 EVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLAN 3172 Query: 2865 QVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTST 2924 + + S++ + A L+ L EKTRW T ++ + GDIL+S+ + Y G T Sbjct: 3173 RKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPE 3232 Query: 2925 YRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNA 2984 +RQ +W T C I S SL+ + + I W+ GLP +S++N I+I N Sbjct: 3233 FRQLIVNKWETFCIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNG 3292 Query: 2985 RRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELD 3044 ++WPL+IDP QA+KWI+ ME + L + + + +Y + +EN ++ G VLL+N+ E L Sbjct: 3293 QQWPLLIDPHRQAHKWIRQME-GSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLA 3351 Query: 3045 PILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFM 3104 P L+ +L K +++ G IR+GD+ EY +FR Y++T++ NPH+LP VT++NF Sbjct: 3352 PGLKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFT 3411 Query: 3105 ITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILE 3164 +T +G+QDQLL VV E P LE+++ L+ + + L+E+E+K L +L + G+IL+ Sbjct: 3412 VTFQGLQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILD 3471 Query: 3165 DETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIE 3224 D+ + L SK +NEIS++ E ++ E +I R Y PIA ++L+F +ADL I Sbjct: 3472 DDKIVDTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQIN 3531 Query: 3225 PMYQYSLTWFINLFILSIENSEKSE-------------------------------ILAK 3253 MYQ+SL WF +F+ S+ + K + +L K Sbjct: 3532 YMYQFSLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDK 3591 Query: 3254 RLQILKDHFTYSLYVNVCRSLFEKDKLLFSF--CLTI-------NLLLHERA-INKAEWR 3303 ++ D T S++ V +LF +DKL FSF C I NL+ + + + EW Sbjct: 3592 HIKSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWN 3651 Query: 3304 FLLTGGIGLDNPYA---------------NLCTWLPQKSWDE-------------ICR-- 3333 L GI ++ A WL W + +C+ Sbjct: 3652 IFLYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSL 3711 Query: 3334 ---LDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWE----------------D 3374 + FK + + + + SLE + + PEE E + Sbjct: 3712 LSNVSQWDTFKNSKAVYSLISTPFSSENASLEENTKP-PEETELLNENKETCNPINFPWE 3770 Query: 3375 KANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVL 3434 K FQR+++++ LRP+ + +++FI ++G +++ +L A+ SN PLI + Sbjct: 3771 KLTSFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQ 3830 Query: 3435 SPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAV-KEGTWVVLQNCHLA 3493 + G D LL+FA + ++ +SLG+ Q A ++ KA+ K WV LQNCHLA Sbjct: 3831 THGIDLTNILLRFAQELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLA 3890 Query: 3494 TSWMPTLEKVCEEL-SPEST-HPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANI 3551 TS+MP L + E SP T P+FR+WL+S +FP+ VL+ G+K+ E+P+GL++N+ Sbjct: 3891 TSFMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNL 3950 Query: 3552 IRSYLMDPISD--PEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNET 3609 ++++ + E F + + +KKLL+ LCFF+A++ ER+ +G LGWNI Y+FN + Sbjct: 3951 LQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSS 4010 Query: 3610 DLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVE 3669 DL ++++ L L + ++ALRY+ GE YGGRV D+WD+R L+++L KF NPE+++ Sbjct: 4011 DLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVLK 4070 Query: 3670 NSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDN 3729 + D+ F S K YI ++LP PE+ G++ A + +++ + +N Sbjct: 4071 D-DFSFSR--------SASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIEN 4121 Query: 3730 ILLTQSRSAGAG-----AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMN-- 3782 ++ Q ++ A +S DE+V E+ SD+L +LP + E P+T M+ Sbjct: 4122 LIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMMSSS 4181 Query: 3783 ---------------------TVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLE 3821 T L QE+ RF+KLL I S ++Q AIKG +++ +LE Sbjct: 4182 IWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELE 4241 Query: 3822 EVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEV-------------- 3867 E+ +S LN+++P +W +Y S KPL S+++D + RL F W +V Sbjct: 4242 EIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVT 4301 Query: 3868 -------------------------GPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDL 3902 G P +WL FFF QAFL Q+Y R I +D Sbjct: 4302 VWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDA 4361 Query: 3903 LGFDYEVME---DKEYKH-------------------PPEDGVFIHGLFLDGASWNRKIK 3940 L F + V+ DK+ K GV+I GLF++GA WNR+ K Sbjct: 4362 LTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQK 4421 Query: 3941 KLAESHPKILYDTVPVMWLKPCKRADIPKRPS---------YVAPLYKTSERRGVLSTTG 3991 L +S P + P ++ P K + S + P+Y+T ER +L+TTG Sbjct: 4422 ILEDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFECPVYQTPERSRILATTG 4481 Query: 3992 HSTNFVIAMTLPSDQPKEHWIGRGVALLCQLN 4023 TNF+ ++ L + +P HWI VALLC+ N Sbjct: 4482 LPTNFLTSVYLSTKKPPSHWITMRVALLCEKN 4513 Score = 719 bits (1857), Expect = 0.0 Identities = 440/1227 (35%), Positives = 647/1227 (52%), Gaps = 139/1227 (11%) Query: 759 IQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSP 818 I+ L +L+E E+ W ++ + V+ ++ + LEK S Sbjct: 992 IEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGLPKSD 1051 Query: 819 YALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLD 878 M ++ V +FKQ +P+I + NP L+PRHWEA+ I+G + + V + L Sbjct: 1052 ----MVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLDKNCKVENLLA 1107 Query: 879 MNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDA--VEFVIHSYRETGTFILASVDEI 936 + + Y + +S +A+ E +LEK + K+I W+ + ++H FI+ S+D+I Sbjct: 1108 LKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSIFIIPSIDDI 1167 Query: 937 QMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSS 996 L++ + T++GSP I P + + EW+ L L L+EW+ Q WLYLEP+F S Sbjct: 1168 SAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHS 1227 Query: 997 PDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKG 1056 +I Q+P E F+ V W+ IM + ++ L + T +LE L+ N LE I K Sbjct: 1228 SEIRRQLPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKS 1287 Query: 1057 LNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET----L 1112 L +YLE KRL FPRF+FLSN ELL+IL+++++P VQPHL KCFE I ++ + Sbjct: 1288 LEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPP 1347 Query: 1113 DITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERI 1172 + + S+EGE + L + I + R VE+WLV +E+ M + + K +I Sbjct: 1348 AVKMLISAEGEGLVLPKKI---RVRSAVEQWLVNVEKSMFDVLKKERYIYNIILLFQSQI 1404 Query: 1173 NWVRDWPGQTVLCVSQIF--WTKEVQTAIPMGIKALEQYLKTCN-RQIDDIVTLVRGKLS 1229 + D CV +++E + G+ C+ ++ D+V L + Sbjct: 1405 MFYND-------CVKSFVSSYSREKLEKVHAGLM--------CHLEEVADLVVLDTS--N 1447 Query: 1230 MQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENH--LETKMINAG 1287 + + LGAL++L VH RD++ +L+ KNI + DFEW L+Y W E NA Sbjct: 1448 SRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNAS 1507 Query: 1288 LRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAK 1347 YGYEYLG + RLVITPLTDRC+ TL ALHL+LGG P GPAGTGKTET KDLAK++ K Sbjct: 1508 FTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGK 1567 Query: 1348 QCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAG 1407 CVVFNC + LDY + KFF GL+ GAW+CFDEFN IDLEVLSV+A QILTI+ + Sbjct: 1568 HCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNY 1627 Query: 1408 ADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLY 1467 + + EG E++++ +CAVFITMNP Y G ELPDNLK+LFR VAMMVP Y MIAEI+L+ Sbjct: 1628 SARFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILF 1687 Query: 1468 SCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKY---PNENE 1524 S GF +A LS K+ Y L +QLS Q HY++G+R++K VL AG K ++ +E Sbjct: 1688 SFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSEADE 1747 Query: 1525 EILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQM 1584 ++++ +I + +LPK D+PLFE I D+FP V + K + L I + LQ Sbjct: 1748 TLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQN 1807 Query: 1585 TAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDI-------------CE 1631 + EKI+Q Y + V G M+VG GGKT+ R+L AL + Sbjct: 1808 WSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSAS 1867 Query: 1632 KGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTP------- 1684 K + KV I VLNPK VT+ +LYGQ D + EW+DG+L+ + R++ TP Sbjct: 1868 KISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDI 1927 Query: 1685 ---------------------------------------------DRKWLIFDGPVDAVW 1699 D +W+I DGPVD W Sbjct: 1928 DLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFW 1987 Query: 1700 IENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGW 1759 +EN+N+VLDD + LCL + E I ++ ++ +IFE +L ASPATVSRC M+YM+P LGW Sbjct: 1988 VENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGW 2047 Query: 1760 RPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTK-ELSPTSDTNLVRSLMN 1818 P + SW+ +S + + + V ++FIR K + P D +V +L Sbjct: 2048 EPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCR 2107 Query: 1819 LIDCFMD-----------DFADEVKLKERN--------------DRETY----------S 1843 ++D F D D ++ KE N D T+ Sbjct: 2108 ILDAFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVTFKDIEKRDENTWYPEKNPDKLTK 2167 Query: 1844 LLEGIFLFSLIWSVGASCTDDDRLKFN 1870 +++ +F+F+ W+ G + +D + N Sbjct: 2168 IIQKLFVFAFTWAFGGALNREDEHREN 2194 Score = 167 bits (424), Expect = 1e-40 Identities = 99/297 (33%), Positives = 160/297 (53%), Gaps = 15/297 (5%) Query: 1954 DTIRYSALMELLTTHQKPSIFVGPT---GTGKSVYITNFLLNQLNKEIYKP--------L 2002 DT+ YS + + + Q +I + T TG S T + NK++ K Sbjct: 2369 DTLLYSEIKKSSSLKQNITILIPETHKTATGSSDNPTKKPEVRTNKKLLKNNDHKGVVVS 2428 Query: 2003 LINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIEL 2062 INFS TAA+T+ +++ KL +R K G P R+++F+DD+NMP ++YGAQPP+EL Sbjct: 2429 TINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPPLEL 2488 Query: 2063 LRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKS 2122 +RQ LD YD + + + D+ I+ A P N ++PR ++HF+++ + S Sbjct: 2489 IRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPV---VNDISPRLLKHFSMLVLPHPSQDI 2545 Query: 2123 MYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRD 2182 + TIF L + I F E QI++ ++ +Y + +N+LPTP K HY+FNLRD Sbjct: 2546 LCTIFQAHLGIYFSI-NNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLRD 2604 Query: 2183 FSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRN 2239 +++ G+ + + E+ L+VHE RV++DRL+D TD+S + L N Sbjct: 2605 MFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELEN 2661 >gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens] Length = 798 Score = 478 bits (1230), Expect = e-134 Identities = 284/824 (34%), Positives = 446/824 (54%), Gaps = 48/824 (5%) Query: 3219 DLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKD 3278 DL+ I PMYQ+SL F +F ++E + E L +R+ L D T+S+Y R LFE D Sbjct: 3 DLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECD 62 Query: 3279 KLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLP 3338 KL + LT +LL R +N E FLL + A+ +L ++W + L + Sbjct: 63 KLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGT--ASPVEFLSHQAWGAVKVLSSME 120 Query: 3339 AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQ 3398 F + R+ WKK +S P E P+EW++K QR+ ++R +RPD++ L+ Sbjct: 121 EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKT-ALQRLCMLRAMRPDRMTYALR 179 Query: 3399 EFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQG------ 3452 +F+ +LG ++ D A +F +S P+ F+LSPG DP LK + QG Sbjct: 180 DFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDP----LKDVESQGRKLGYT 235 Query: 3453 YGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPEST 3512 + ++SLGQGQ +A L+ A K+G WV+LQN HL W+ TLEK EE S E++ Sbjct: 236 FNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENS 294 Query: 3513 HPDFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFG 3567 HP+FR+++++ P+P+ P +L+N +K+TNE P G+ AN+ ++ +D + + Sbjct: 295 HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA--LDNFTQ-DTLE 351 Query: 3568 SCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEE 3627 C + EFK +L+ LC+FHA+V ERRKFGP GWN Y FN DL ISV L+ FL + Sbjct: 352 MCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAK 411 Query: 3628 LPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSG 3687 +PY+ LRY+ GE YGG +TDDWDRR R+ L +F PE++E + + + +P + Sbjct: 412 VPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEG---ELSLAPGFPLPGNM 468 Query: 3688 DHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSA----GAGAK 3743 D+ Y +Y +P ++G++ NA+I ++ LF +L Q R + GAGA Sbjct: 469 DYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGA- 527 Query: 3744 SSDEVVNEVASDILGKLPNNFDIEAAMRRYP--TTYTQSMNTVLVQEMGRFNKLLKTIRD 3801 + +E V + +IL ++ + F+I M + T Y V QE GR N L + I+ Sbjct: 528 TREEKVKALLEEILERVTDEFNIPELMAKVEERTPYI----VVAFQECGRMNILTREIQR 583 Query: 3802 SCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFL 3861 S ++ +KG M++ +E + +++ +PE W ++YPS L ++ D L R+K L Sbjct: 584 SLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKEL 643 Query: 3862 QQWY-EVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHP 3918 + W + P WL+GFF Q+FLT Q+ ARK P+D + ++ + +E++ P Sbjct: 644 EAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSP 703 Query: 3919 PEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLY 3978 P +G +IHGLF++GA W+ + + E+ K L +PVM++K R Y P+Y Sbjct: 704 PREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVY 763 Query: 3979 KTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022 KTS+R +V L + + W+ GVALL Q+ Sbjct: 764 KTSQR---------GPTYVWTFNLKTKENPSKWVLAGVALLLQI 798 >gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] Length = 4753 Score = 225 bits (574), Expect = 6e-58 Identities = 337/1643 (20%), Positives = 631/1643 (38%), Gaps = 304/1643 (18%) Query: 833 DFKQHIPLIQVICNPGLRPRHWEAMSAIVGY-PLQPSDDSTVSSFLDMNLEPYIDRFEGI 891 +F+ ++PL+ + + + + + + +G LQ + T+ L L + DR + Sbjct: 1082 EFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQV 1141 Query: 892 SEAASKEYSLEKAMEKMITEWDA-----VEFVIHSY-----------------------R 923 + ++ ++ + ++ W+A + F++H + Sbjct: 1142 WQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDK 1201 Query: 924 ETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKV 983 ++GTFIL+ +Q + + + + K EW + L +L+ WL Sbjct: 1202 DSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTF 1261 Query: 984 QATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTID------ 1037 Q W++L + I + RF +D +R +MR + D VL++V Sbjct: 1262 QQKWIFLNKVLHEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPY 1321 Query: 1038 ---RMLERLKKSNEL-LELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQ 1093 + L++L ++ + LE I+ L L FPR FFLS+ EL+ +L+ + Q Sbjct: 1322 FQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQ 1381 Query: 1094 PHLKKCFEGIAKVEF----TETLDITHMKSSEGEVVELIEIISTAKARGQ---------- 1139 +++CF + V F T + +SS + +E ++ A G+ Sbjct: 1382 LWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQ-VEALAVLGAGGEEVKLQGPLPL 1440 Query: 1140 ---VEKWLVELERVM-INSIHKVTG-------------DATFAYTKYERI-------NW- 1174 + KWL LE+ + + +H + G +A K ++ +W Sbjct: 1441 HPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWI 1500 Query: 1175 --VRDWPGQTVLCVSQIFWTKEVQTAI-PMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQ 1231 V+ +P Q VL ++ W E++ A+ G A+ + R+++ +V +R + + Q Sbjct: 1501 DLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLAM---VSMHMRKLEVLVNFMRAQRASQ 1557 Query: 1232 NRVTL---------GALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETK 1282 +L AL+V+ V RD+ L + +SD +DF W+ QL+Y+ H+ K Sbjct: 1558 GGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPK 1617 Query: 1283 ------------------------MINAGLRYGYEYLGNSPRLVITP--LTDRCYRTLFG 1316 ++ Y YEYLG PRL P L +R L Sbjct: 1618 SPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLL 1675 Query: 1317 ALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAW 1376 AL G GP G GK LA+A+ +Q V+ CS ++ L + G L GAW Sbjct: 1676 ALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAW 1735 Query: 1377 ACFDEFNRIDLEVLSVVAQQI-----LTIQRGINAGADILMFEGTELKLDPTCAV---FI 1428 ++ +++ +LS + Q++ L A + + T+ +L + + Sbjct: 1736 LLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHV 1795 Query: 1429 TMNPGY-------AGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKI 1481 ++ GY A S +P NL L R VA+ +PD +AE+ L G A ++ ++ Sbjct: 1796 SVRLGYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRL 1855 Query: 1482 VATYRLCSEQLSSQHHYDYGM------RAVKSVLTAAGNLKLKYPNE---NEEILLLRSI 1532 + L E +S + ++++ K + P EE LLRS Sbjct: 1856 SKFFSLERELVSGPLPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRSP 1915 Query: 1533 IDVNLPKFLSHDLPLFEGITSDLFPGVK--LPKP-DYNDLLAAIKDNCASMNLQMTAFFS 1589 + L H+L G+ LFP L +P Y + + + + L + Sbjct: 1916 LFSILNGLHLHNL---RGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDIL 1972 Query: 1590 EKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVL------AGALNDICEKGLMEENKVQIT 1643 + Q+ + + G +++G GKT+ + L A+ D +G V+IT Sbjct: 1973 GSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGC---QPVEIT 2029 Query: 1644 VLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRK-----------WLIFD 1692 L P ++ + G + W G+ RA +K W+I D Sbjct: 2030 HLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICD 2087 Query: 1693 GPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYM 1752 G + W++++ +L + +L L SG+ I P L+ E D SP V C +++ Sbjct: 2088 GASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWC 2147 Query: 1753 EPHMLGWRPLMLSWVNLLPASVSVIQKEF--IMGLFDRMVPVSVEF---------IRKHT 1801 W+ ++ + + LP + + + + + +VP ++ F ++ H Sbjct: 2148 GGEQT-WQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHG 2206 Query: 1802 KE---LSPTSDTNLVRSLMNLIDCFMD------------DFADEVKLKERNDRETY---- 1842 ++ T++ R L +L+D + ++D V R+ + ++ Sbjct: 2207 QQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRS 2266 Query: 1843 --------------SLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNT 1888 L FLF+LIW GA +F I + IS Sbjct: 2267 QVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPS----RFWPIFDTFIRDSIS------ 2316 Query: 1889 FKLQSGTEQTSSKALTVPF---PEKGTIYDY--QFVTEGIGKWEPWIKKLKEAPPIPKDV 1943 +L + E S AL PE GT+ + Q+++ I K Sbjct: 2317 -RLSNYPEPPPS-ALVFDLHVSPEDGTLVPFTGQYLSSHI-----------------KGT 2357 Query: 1944 MFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLL 2003 + P++ T R +++LL + +P + G TGKS ++ L+ + IY P+ Sbjct: 2358 L--GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFV-EVLVEPHHPYIYSPIH 2414 Query: 2004 INFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPARE-VYGAQPPIEL 2062 FS+ + + + ++ ++D+++ + QP +E Sbjct: 2415 PAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLET 2474 Query: 2063 LRQWLDHWNWYDLKDCSMIKLVDIQ----IMCAMGPPGGGRNPVTPRYMRHFNIITINEF 2118 LRQ +D + S ++L +Q + + PG P+ PR R F ++ + Sbjct: 2475 LRQAMDGTVYAH----STLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESM 2530 Query: 2119 SDKSMYTIFSRILTWHLEICYKFP--DEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHY 2176 + ++ I+ LE +FP + L +V ++ ++ +P+P HY Sbjct: 2531 TQATLLERHVPIIQAWLE---RFPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHY 2587 Query: 2177 LFNLRDFSRV-------------------------------IQGVCLSRPETTETTEVIK 2205 F+L S + ++G CL+ T + Sbjct: 2588 HFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLT---VMMATRNVV 2644 Query: 2206 RLWVHEVLRVYYDRLLDNTDRSW 2228 RLW+HE R + DRL +RS+ Sbjct: 2645 RLWLHEAQRTFCDRLDSPRERSY 2667 Score = 103 bits (257), Expect = 3e-21 Identities = 169/767 (22%), Positives = 304/767 (39%), Gaps = 113/767 (14%) Query: 3010 LYVIKLSEPDYVRTLENCIQFGTPVLLENVG-----EELDPILEPLLLKQTFKQGGSTCI 3064 L V+ ++P+ L+ G PVLL NV EEL +L+ L Sbjct: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNVELGLGCEELQWLLQREQL------------ 3711 Query: 3065 RLGDSTIEYAPDFRFYITTKLR----NPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVA 3120 S + P F Y++T L E + +L+ + E +++Q+L ++ Sbjct: 3712 ----SPPQVQPGFCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILC 3767 Query: 3121 QERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALAN 3180 +E P+LE Q L ++ + + ++ E+++L +L + + K L + Sbjct: 3768 REYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNP---KRQKPAKFLRNIVRAQG 3824 Query: 3181 EISQKQEVAEETE-KKIDTTRMG--YRPIAIHSSILFFSLADLANIEPMYQYSLTWFINL 3237 ++ Q + EE E +K+ + YRP+ H + +L+ L N+ P++ S ++ + Sbjct: 3825 KLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAV 3884 Query: 3238 FILSIENSEKSEI-----LAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLL 3292 ++++ + EI LA L L+ H T L + +L L + LL Sbjct: 3885 TKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQ 3944 Query: 3293 HERAINKAEWRFLLTGGIGLD------NPYANLC--TWLPQKSWDEICRLDDLPAFKTIR 3344 ++ E R L G+ P +++ WL K+W E L+ LP F + Sbjct: 3945 ATGKASELE-RLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLC 4003 Query: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404 W+ P + + Q++++ R LRP+ + L +F + Sbjct: 4004 ASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSL 4063 Query: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAAL------LKFADDQGYGGSKL 3458 LGR ++ + F S P++ +L P P A L K A G +L Sbjct: 4064 LGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQL 4122 Query: 3459 SSLSLG-QGQGPIAMKM--LEKAVKEGTWVVLQNCHLATSWMPTLEKVCEEL-------- 3507 ++LG + P+++ + L +A+ EG W+VL NCHL W L ++ EL Sbjct: 4123 QVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVA 4182 Query: 3508 ---------SPES-----THPDFRMWL--TSYPSPNFPVSVLQNGVKM-TNEAPKGLRAN 3550 PES H DFR+WL + S + P + Q+ + + N++ + Sbjct: 4183 DLESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWNQSLE----- 4237 Query: 3551 IIRSYLMDPISDPEFFGSCKKPEEFKK--LLYGLCFFHALVQERRKFGPLGWNIPYEFNE 3608 + L+D + + + P + LL+GL L R + W+ + Sbjct: 4238 -LGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWS---QVTL 4293 Query: 3609 TDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELV 3668 T + + QL L+ P A++ + YGG + D DR L S+ +P Sbjct: 4294 TQVLQTQDQLWASLSN----PRAAMQELAASVFYGGPLGDTEDREALISLTQACLSP--- 4346 Query: 3669 ENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANAD 3715 SSG + P + + L P PE+ ++A A+ Sbjct: 4347 --------SSGSWVQP-------HTPQSLLATLMPLPELRELDAMAE 4378 Score = 102 bits (253), Expect = 1e-20 Identities = 166/747 (22%), Positives = 281/747 (37%), Gaps = 116/747 (15%) Query: 2321 EHISRISRILKQPRSHALLV-GVGGSGRQSVTRLAAHMADYSVFQVE------ISKGYDT 2373 +H++R+ R+L +PR H LL+ G G+GR + LA+ + F + I + Sbjct: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRD 2929 Query: 2374 TEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEI 2433 WH + + + A GV L T L + L +G P + + I Sbjct: 2930 ASWHAGM--LSQPVALLVPSGVDLTT---------LHRLLALATSGSFPGQYTEADLDRI 2978 Query: 2434 CDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRK---FP 2490 + L R+ KQ + L C S LH+ IGD ++ F Sbjct: 2979 GE---HLPRENLGVKQNIKKEMVLQRFHQQVC-SHLHLFFL---IGDKQAHKQLPSTLFL 3031 Query: 2491 ALVNCCT--IDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSF 2548 L+ T ID ++ W + AL VA LE + S + DG S ++K+ Sbjct: 3032 RLLQLATASIDRYEPWDQAALAKVAQHHLEGAQ-SVPLDDGSWKY-PDLQASIPSVAKAM 3089 Query: 2549 -FVELQRYNY----------VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDS 2597 + L +Y VTP ++L+ + TF +L ++ ++ +R + LE L Sbjct: 3090 ALIHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRM 3149 Query: 2598 ASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMA 2657 + T + L QLK + K + +E+ + + + + E + A Sbjct: 3150 LIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQENLIENLARQ 3209 Query: 2658 SKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGI 2717 A++ + +A L + ++ L L L D ++S ++PP V V +A+C Sbjct: 3210 RDALQAQREAFLE---QMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMC----- 3261 Query: 2718 KADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPN-P 2776 D TG W AK+LL F Q L + K+ I + +I+ + I P Sbjct: 3262 --DLFHHETG--------WASAKQLLCTEDFYQELVFFPKEKITDS--ELIKLHLILKAP 3309 Query: 2777 DFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQA 2836 +R S A L W+ A+ Y P + L E L ++QA Sbjct: 3310 GMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLT-------REQA 3362 Query: 2837 ALKEVQDKLARLQDTLELN---KQKKADLENQVDLCSKKLERAE-------QLIGGLGGE 2886 L Q + Q+TLE N + D + + +K L +A+ + L Sbjct: 3363 RLGYYQ---FQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKAALLTP 3419 Query: 2887 KTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSD 2946 W+ +L + + GD L+ S + YLG F RQ EW LC+G Sbjct: 3420 MRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGP 3479 Query: 2947 D---------------------------CSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGI 2979 D S++ L W+ P + G+ Sbjct: 3480 DDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGL 3539 Query: 2980 II-----MNARRWPLMIDPQSQANKWI 3001 ++ ++ RWPL++DP ++A W+ Sbjct: 3540 LLRSPTHYSSCRWPLLLDPSNEALIWL 3566 >gi|89274173 dynein heavy chain domain 2 isoform 2 [Homo sapiens] Length = 457 Score = 137 bits (344), Expect = 3e-31 Identities = 92/366 (25%), Positives = 184/366 (50%), Gaps = 18/366 (4%) Query: 165 YYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDS---IVTLSDEMREDYLLSVRKS 221 Y Y+ +++ + P++ WL+H+L L+P+ LK + + +L +E+ D+ S+++ Sbjct: 96 YIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLESLINEVSSDFENSMKRY 155 Query: 222 IVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAV 281 +V VL P K + + LP ++ PW S++ A + I +L+ ++PTM + Sbjct: 156 LVQSVLVKPPVKSLEDEGGPLPESPVGLDY-SNPWHSSYVQARNQIFSNLHIIHPTMKML 214 Query: 282 LDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQ 341 LDL +T F L+D + ++ S + + +A+E ++ W+P+V N++ Sbjct: 215 LDLGYTTFADTVLLDFTGI-RAKGPIDCESLKTDLSIQTRNAEEKIMNTWYPKVINLF-- 271 Query: 342 GNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPG 401 KK+ G KL++F++C + LM+ QL+DL +++ F L P D R P Sbjct: 272 --TKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF-DPKDQQRL---PI 325 Query: 402 FIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLK 461 F + L D+D ++F P D D L++ + + +A+ V + + L + T L Sbjct: 326 FKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDTELP 385 Query: 462 PIILNEIVDAHKEKIKEVIMKESVAPTEHLRLY-DKYDFLITRKAERDVDNFLAENHSYE 520 +L+ VD +K + + +H Y +KY++L+ A +++ F E+H+++ Sbjct: 386 EHVLHWAVDT----LKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTEDHTFD 441 Query: 521 KIIDEI 526 + +E+ Sbjct: 442 EYTEEL 447 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 46.2 bits (108), Expect = 7e-04 Identities = 105/548 (19%), Positives = 208/548 (37%), Gaps = 96/548 (17%) Query: 2368 SKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEI------ 2421 SK DT + L+ L + E E + V KEES V ++L E Sbjct: 534 SKLTDTLVSKQQLEQRLMQLMESEQKRVN-------KEESLQMQVQDILEQNEALKAQIQ 586 Query: 2422 ---PNLFALDEKQEICDKMRQLDRQRDKT-KQTDGSPIALFNMFIDHCRSQLHVVLAMSP 2477 + A + +++ ++ ++DK KQT+ S + D S+ + + Sbjct: 587 QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER----DRLTSKEEELKDIQN 642 Query: 2478 IGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSF 2537 + + ++K AL N QA A+ LE+++ S ++D I + + Sbjct: 643 MNFLLKAEVQKLQALAN--------------EQAAAAHELEKMQQSVYVKDDKIRLLEEQ 688 Query: 2538 HTSTIDLSKSFFVELQRYNYVTPTSYLELISTF-----KLLLEKKRSEVMKMKKRYEVGL 2592 I F L N + +L + K ++E+ + + ++ + Sbjct: 689 LQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVE 748 Query: 2593 EKLDSASSQVATMQMELEALHPQLKVASKEVDEMM-----------IMIEKESVEVAKTE 2641 E L++ QVAT + EL A+ + +KEV ++ ++ E + V K Sbjct: 749 ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808 Query: 2642 KIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPP 2701 KI +E + E + A K++ DL + L+ + + AQ +++ ++ Sbjct: 809 KIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866 Query: 2702 AGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIP 2761 +K E + +K + +K D +GK ++D LQ +E K ++ Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQD--------------LQEENESLKAHVQ 912 Query: 2762 PAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAE 2821 + ++ AS+A++ ++++ ++ K+ +L E Sbjct: 913 ---------------EVAQHNLKEASSASQ-----------FEELEIVLKEKENELKRLE 946 Query: 2822 GELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQV---DLCSKKLERAEQ 2878 LK L K L++VQD+ + +E KQ+ + + K + E+ Sbjct: 947 AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREK 1006 Query: 2879 LIGGLGGE 2886 I GL E Sbjct: 1007 EISGLWNE 1014 >gi|118498368 kinectin 1 isoform c [Homo sapiens] Length = 1300 Score = 46.2 bits (108), Expect = 7e-04 Identities = 105/548 (19%), Positives = 208/548 (37%), Gaps = 96/548 (17%) Query: 2368 SKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEI------ 2421 SK DT + L+ L + E E + V KEES V ++L E Sbjct: 534 SKLTDTLVSKQQLEQRLMQLMESEQKRVN-------KEESLQMQVQDILEQNEALKAQIQ 586 Query: 2422 ---PNLFALDEKQEICDKMRQLDRQRDKT-KQTDGSPIALFNMFIDHCRSQLHVVLAMSP 2477 + A + +++ ++ ++DK KQT+ S + D S+ + + Sbjct: 587 QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER----DRLTSKEEELKDIQN 642 Query: 2478 IGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSF 2537 + + ++K AL N QA A+ LE+++ S ++D I + + Sbjct: 643 MNFLLKAEVQKLQALAN--------------EQAAAAHELEKMQQSVYVKDDKIRLLEEQ 688 Query: 2538 HTSTIDLSKSFFVELQRYNYVTPTSYLELISTF-----KLLLEKKRSEVMKMKKRYEVGL 2592 I F L N + +L + K ++E+ + + ++ + Sbjct: 689 LQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVE 748 Query: 2593 EKLDSASSQVATMQMELEALHPQLKVASKEVDEMM-----------IMIEKESVEVAKTE 2641 E L++ QVAT + EL A+ + +KEV ++ ++ E + V K Sbjct: 749 ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808 Query: 2642 KIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPP 2701 KI +E + E + A K++ DL + L+ + + AQ +++ ++ Sbjct: 809 KIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866 Query: 2702 AGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIP 2761 +K E + +K + +K D +GK ++D LQ +E K ++ Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQD--------------LQEENESLKAHVQ 912 Query: 2762 PAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAE 2821 + ++ AS+A++ ++++ ++ K+ +L E Sbjct: 913 ---------------EVAQHNLKEASSASQ-----------FEELEIVLKEKENELKRLE 946 Query: 2822 GELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQV---DLCSKKLERAEQ 2878 LK L K L++VQD+ + +E KQ+ + + K + E+ Sbjct: 947 AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREK 1006 Query: 2879 LIGGLGGE 2886 I GL E Sbjct: 1007 EISGLWNE 1014 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 46.2 bits (108), Expect = 7e-04 Identities = 105/548 (19%), Positives = 208/548 (37%), Gaps = 96/548 (17%) Query: 2368 SKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEI------ 2421 SK DT + L+ L + E E + V KEES V ++L E Sbjct: 534 SKLTDTLVSKQQLEQRLMQLMESEQKRVN-------KEESLQMQVQDILEQNEALKAQIQ 586 Query: 2422 ---PNLFALDEKQEICDKMRQLDRQRDKT-KQTDGSPIALFNMFIDHCRSQLHVVLAMSP 2477 + A + +++ ++ ++DK KQT+ S + D S+ + + Sbjct: 587 QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASER----DRLTSKEEELKDIQN 642 Query: 2478 IGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSF 2537 + + ++K AL N QA A+ LE+++ S ++D I + + Sbjct: 643 MNFLLKAEVQKLQALAN--------------EQAAAAHELEKMQQSVYVKDDKIRLLEEQ 688 Query: 2538 HTSTIDLSKSFFVELQRYNYVTPTSYLELISTF-----KLLLEKKRSEVMKMKKRYEVGL 2592 I F L N + +L + K ++E+ + + ++ + Sbjct: 689 LQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVE 748 Query: 2593 EKLDSASSQVATMQMELEALHPQLKVASKEVDEMM-----------IMIEKESVEVAKTE 2641 E L++ QVAT + EL A+ + +KEV ++ ++ E + V K Sbjct: 749 ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808 Query: 2642 KIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPP 2701 KI +E + E + A K++ DL + L+ + + AQ +++ ++ Sbjct: 809 KIKSVEELL--EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQ 866 Query: 2702 AGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIP 2761 +K E + +K + +K D +GK ++D LQ +E K ++ Sbjct: 867 NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQD--------------LQEENESLKAHVQ 912 Query: 2762 PAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAE 2821 + ++ AS+A++ ++++ ++ K+ +L E Sbjct: 913 ---------------EVAQHNLKEASSASQ-----------FEELEIVLKEKENELKRLE 946 Query: 2822 GELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQV---DLCSKKLERAEQ 2878 LK L K L++VQD+ + +E KQ+ + + K + E+ Sbjct: 947 AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREK 1006 Query: 2879 LIGGLGGE 2886 I GL E Sbjct: 1007 EISGLWNE 1014 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 44.3 bits (103), Expect = 0.002 Identities = 62/331 (18%), Positives = 133/331 (40%), Gaps = 16/331 (4%) Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617 VT + L+ + +++LE + ++ K KK E + + + ++ L L + + Sbjct: 967 VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026 Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677 +++E + EK+ E+ KT + ++ D T ++Q +A E LA L+ Sbjct: 1027 AMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQ 1086 Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737 +ALA ++ AQ +K ++ + + + E + + + G+++E Sbjct: 1087 AALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKT 1146 Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDF----VPEKIRNASTAAEGL 2793 + L Q L + + NI++K + E + S A E L Sbjct: 1147 ELEDTLDSTAAQQELRSKREQEV-----NILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL 1201 Query: 2794 CKWVIAMDSYDKVAKIVAPKKIKLAAAEGEL----KIAMDGLRKKQAALKEVQDKLARLQ 2849 + ++ +V + K L GEL K+ + G + K+V+ +L LQ Sbjct: 1202 AE---QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQ 1258 Query: 2850 DTLELNKQKKADLENQVDLCSKKLERAEQLI 2880 ++ + +L ++V +L+ L+ Sbjct: 1259 VKFNEGERVRTELADKVTKLQVELDNVTGLL 1289 >gi|110347443 TATA element modulatory factor 1 [Homo sapiens] Length = 1093 Score = 43.9 bits (102), Expect = 0.003 Identities = 125/601 (20%), Positives = 230/601 (38%), Gaps = 82/601 (13%) Query: 2484 NRLRKFPALV-NCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTI 2542 NRL F L +CC+ D F+ ++Q++ SR + EI +E+ + S+ Sbjct: 305 NRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIVNSST 364 Query: 2543 DLSKSFFV-----ELQRYNYVTPTSYLEL-----------------------ISTFKLLL 2574 SK+ E V PT E+ I+ + +L Sbjct: 365 PKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVL 424 Query: 2575 EKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKE----------VD 2624 +K + + + E EK D + V + +LE QL SKE + Sbjct: 425 DKVAEQCEPAESQPEALSEKEDVCKT-VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLK 483 Query: 2625 EMMIMIEKESVEVAK-----TEKIVKADETI---ANEQAMASKAIKDECDADLAGALPIL 2676 + M +++ES ++ T++I +A++ + E+ A K IK+ +LA L Sbjct: 484 DEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKN-IKEELATRLNSS 542 Query: 2677 ESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKA-DKIPDPTGS--GKKIE 2733 E+A D L +D + M+ K + I+K ++A DK + + KK++ Sbjct: 543 ETA----DLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVK 598 Query: 2734 DFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKN-----YIPNPDFVPEKIRNAST 2788 + + L + + + + ++NI + R+ + D + EK R+ Sbjct: 599 ELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQA 658 Query: 2789 AAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARL 2848 A + K + + K A K + A E L M + AAL++ Q++ + Sbjct: 659 ALDSAYKELTDLH------KANAAKDSE--AQEAALSREMKAKEELSAALEKAQEEARQQ 710 Query: 2849 QDTLELN-KQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGD 2907 Q+TL + + L+ ++K + IG L + EL Q + T Sbjct: 711 QETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRP 770 Query: 2908 ILIS-SGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIA 2966 +L + A LG +QT W L K + +L+ E T + Sbjct: 771 LLRQIENLQATLG--------SQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELL 822 Query: 2967 GLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLS--EPDYVRTL 3024 S+++ ++ +S+ N+ K +E N+ Y ++L + +YVRTL Sbjct: 823 ANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCK-LEDENNRYQVELENLKDEYVRTL 881 Query: 3025 E 3025 E Sbjct: 882 E 882 >gi|5901944 elastin microfibril interfacer 1 [Homo sapiens] Length = 1016 Score = 41.6 bits (96), Expect = 0.016 Identities = 28/117 (23%), Positives = 60/117 (51%), Gaps = 8/117 (6%) Query: 2777 DFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRK--- 2833 D + E++ A A LC + +V++I++ + ++ +EG+L++ GL Sbjct: 465 DLLEEQVAGAMQACGQLCSGAPG-EQDSQVSEILSALERRVLDSEGQLRLVGSGLHTVEA 523 Query: 2834 ----KQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGE 2886 +QA L+ +Q+ + RLQD ++ + A+ +++L + +L + E L+ G E Sbjct: 524 AGEARQATLEGLQEVVGRLQDRVDAQDETAAEFTLRLNLTAARLGQLEGLLQAHGDE 580 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 40.8 bits (94), Expect = 0.027 Identities = 61/328 (18%), Positives = 129/328 (39%), Gaps = 7/328 (2%) Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617 VT + ++ LLLE + S++ K +K E L + S +++ L L + + Sbjct: 999 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1058 Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677 ++++ + EK E+ K ++ + + + EQ + + +E A L L+ Sbjct: 1059 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1118 Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737 +ALA + ++KS++ A + E + + + G+++E G Sbjct: 1119 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1178 Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWV 2797 + L Q L + + + + I + +++R A G Sbjct: 1179 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI--HEAAVQELRQRHGQALGELAEQ 1236 Query: 2798 IAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ 2857 + K A ++ L A EL+ + L Q A +E + + RL+ L+ + Sbjct: 1237 LEQARRGKGA--WEKTRLALEAEVSELRAELSSL---QTARQEGEQRRRRLELQLQEVQG 1291 Query: 2858 KKADLENQVDLCSKKLERAEQLIGGLGG 2885 + D E ++KL+RA+ + + G Sbjct: 1292 RAGDGERARAEAAEKLQRAQAELENVSG 1319 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 40.8 bits (94), Expect = 0.027 Identities = 61/328 (18%), Positives = 129/328 (39%), Gaps = 7/328 (2%) Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617 VT + ++ LLLE + S++ K +K E L + S +++ L L + + Sbjct: 991 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1050 Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677 ++++ + EK E+ K ++ + + + EQ + + +E A L L+ Sbjct: 1051 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1110 Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737 +ALA + ++KS++ A + E + + + G+++E G Sbjct: 1111 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1170 Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWV 2797 + L Q L + + + + I + +++R A G Sbjct: 1171 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI--HEAAVQELRQRHGQALGELAEQ 1228 Query: 2798 IAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ 2857 + K A ++ L A EL+ + L Q A +E + + RL+ L+ + Sbjct: 1229 LEQARRGKGA--WEKTRLALEAEVSELRAELSSL---QTARQEGEQRRRRLELQLQEVQG 1283 Query: 2858 KKADLENQVDLCSKKLERAEQLIGGLGG 2885 + D E ++KL+RA+ + + G Sbjct: 1284 RAGDGERARAEAAEKLQRAQAELENVSG 1311 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 40.8 bits (94), Expect = 0.027 Identities = 61/328 (18%), Positives = 129/328 (39%), Gaps = 7/328 (2%) Query: 2558 VTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLK 2617 VT + ++ LLLE + S++ K +K E L + S +++ L L + + Sbjct: 1032 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1091 Query: 2618 VASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILE 2677 ++++ + EK E+ K ++ + + + EQ + + +E A L L+ Sbjct: 1092 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1151 Query: 2678 SALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWG 2737 +ALA + ++KS++ A + E + + + G+++E G Sbjct: 1152 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1211 Query: 2738 PAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWV 2797 + L Q L + + + + I + +++R A G Sbjct: 1212 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI--HEAAVQELRQRHGQALGELAEQ 1269 Query: 2798 IAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ 2857 + K A ++ L A EL+ + L Q A +E + + RL+ L+ + Sbjct: 1270 LEQARRGKGA--WEKTRLALEAEVSELRAELSSL---QTARQEGEQRRRRLELQLQEVQG 1324 Query: 2858 KKADLENQVDLCSKKLERAEQLIGGLGG 2885 + D E ++KL+RA+ + + G Sbjct: 1325 RAGDGERARAEAAEKLQRAQAELENVSG 1352 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 39.3 bits (90), Expect = 0.080 Identities = 42/194 (21%), Positives = 87/194 (44%), Gaps = 32/194 (16%) Query: 2506 EDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPT---- 2561 E+A + +A R E E E + C + K+ H ++ + V+++R N Sbjct: 1387 EEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEI-EDLMVDVERSNAAAAALDKK 1445 Query: 2562 --SYLELISTFKLLLEKKRSEV--------------MKMKKRYEVGLEKLDSASSQVATM 2605 ++ ++++ +K E+ +SE+ K+K YE LE L++ + + Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNL 1505 Query: 2606 QMELEALHPQLKVASK---EVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKA-- 2660 Q E+ L QL + K E++++ +E E +E+ + +A+ ++ +E+ +A Sbjct: 1506 QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA--LEEAEASLEHEEGKILRAQL 1563 Query: 2661 ----IKDECDADLA 2670 IK E + LA Sbjct: 1564 EFNQIKAEIERKLA 1577 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 149,013,420 Number of Sequences: 37866 Number of extensions: 6729292 Number of successful extensions: 19748 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 44 Number of HSP's successfully gapped in prelim test: 108 Number of HSP's that attempted gapping in prelim test: 18256 Number of HSP's gapped (non-prelim): 1111 length of query: 4024 length of database: 18,247,518 effective HSP length: 122 effective length of query: 3902 effective length of database: 13,627,866 effective search space: 53175933132 effective search space used: 53175933132 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.