Guide to the Human Genome
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Search of human proteins with 149999608

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149999608 surfactant protein C [Homo sapiens]
         (197 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149999608 surfactant protein C [Homo sapiens]                      392   e-109
gi|59806343 leukocyte cell derived chemotaxin 1 isoform 2 precur...    42   3e-04
gi|5901932 leukocyte cell derived chemotaxin 1 isoform 1 precurs...    42   3e-04
gi|32698950 hypothetical protein LOC283870 [Homo sapiens]              37   0.011
gi|59858535 trefoil factor interactions(z) 1 [Homo sapiens]            34   0.070
gi|169215507 PREDICTED: similar to hCG1732289 [Homo sapiens]           28   6.6  
gi|190341084 HECT domain containing 2 isoform a [Homo sapiens]         28   6.6  
gi|17158025 RNA pseudouridylate synthase domain containing 1 [Ho...    28   6.6  
gi|16418451 hypothetical protein LOC116328 [Homo sapiens]              28   6.6  
gi|239753040 PREDICTED: hypothetical protein XP_002345331 [Homo ...    27   8.6  
gi|239747598 PREDICTED: hypothetical protein XP_002347782 [Homo ...    27   8.6  
gi|239741463 PREDICTED: hypothetical protein XP_002342210 [Homo ...    27   8.6  
gi|145976946 hypothetical protein LOC653784 [Homo sapiens]             27   8.6  
gi|27436867 slit and trk like 4 protein [Homo sapiens]                 27   8.6  

>gi|149999608 surfactant protein C [Homo sapiens]
          Length = 197

 Score =  392 bits (1007), Expect = e-109
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MDVGSKEVLMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVVVVLIVVVIVGALLMGLHM 60
           MDVGSKEVLMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVVVVLIVVVIVGALLMGLHM
Sbjct: 1   MDVGSKEVLMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVVVVLIVVVIVGALLMGLHM 60

Query: 61  SQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPGTC 120
           SQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPGTC
Sbjct: 61  SQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPGTC 120

Query: 121 CYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAF 180
           CYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAF
Sbjct: 121 CYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAF 180

Query: 181 LGMAVSTLCGEVPLYYI 197
           LGMAVSTLCGEVPLYYI
Sbjct: 181 LGMAVSTLCGEVPLYYI 197


>gi|59806343 leukocyte cell derived chemotaxin 1 isoform 2 precursor
           [Homo sapiens]
          Length = 333

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 45/199 (22%), Positives = 79/199 (39%), Gaps = 14/199 (7%)

Query: 3   VGSKEVLMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVV--VVLIVVVIVGALLMGLHM 60
           VG  +V   SPP Y+         P  P  L ++  VV++   VL++   +GA       
Sbjct: 13  VGPDDVEFCSPPAYATLTVK----PSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGS 68

Query: 61  SQKHTEMVLEMSIGAP--EAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPG 118
                 +   MSI     +    +    +L T    S     + V D+Q  +   + A G
Sbjct: 69  DSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGG 128

Query: 119 TCCYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDP 178
             CYI       IP + A+T++  + ++E  +        S +  A  +         D 
Sbjct: 129 EKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPV------KDN 182

Query: 179 AFLGMAVSTLCGEVPLYYI 197
           +FL   V  LCG++P++++
Sbjct: 183 SFLSSKVLELCGDLPIFWL 201


>gi|5901932 leukocyte cell derived chemotaxin 1 isoform 1 precursor
           [Homo sapiens]
          Length = 334

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 45/199 (22%), Positives = 79/199 (39%), Gaps = 14/199 (7%)

Query: 3   VGSKEVLMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVV--VVLIVVVIVGALLMGLHM 60
           VG  +V   SPP Y+         P  P  L ++  VV++   VL++   +GA       
Sbjct: 13  VGPDDVEFCSPPAYATLTVK----PSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGS 68

Query: 61  SQKHTEMVLEMSIGAP--EAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPG 118
                 +   MSI     +    +    +L T    S     + V D+Q  +   + A G
Sbjct: 69  DSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGG 128

Query: 119 TCCYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDP 178
             CYI       IP + A+T++  + ++E  +        S +  A  +         D 
Sbjct: 129 EKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPV------KDN 182

Query: 179 AFLGMAVSTLCGEVPLYYI 197
           +FL   V  LCG++P++++
Sbjct: 183 SFLSSKVLELCGDLPIFWL 201


>gi|32698950 hypothetical protein LOC283870 [Homo sapiens]
          Length = 228

 Score = 37.0 bits (84), Expect = 0.011
 Identities = 35/168 (20%), Positives = 65/168 (38%), Gaps = 15/168 (8%)

Query: 36  LLIVVVVVVLIVVVIVGALLMGLHMSQKHTEMVLEMSIGAPEAQQR-------LALSEHL 88
           LL+++++V+  V ++ G LL       K     L M++ +P   +        +A +   
Sbjct: 33  LLLLLLLVLAAVGIVAGGLLGSAQGPPKPRLQTLRMTLPSPHMPRPNQTILVDVARNAAT 92

Query: 89  VTTATFSIGSTGLVVYDYQQLLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQMEC 148
           +T        +  V++D Q   I Y+P     C++  +      +L  L        ++ 
Sbjct: 93  ITVTPPQSNHSWAVLFDGQSGCICYRPEEHQVCFLRLMEDSDRETLRLL--------VDT 144

Query: 149 SLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAFLGMAVSTLCGEVPLYY 196
           S   +  VP+      +   A       DPA  G  V  LC   P+Y+
Sbjct: 145 SKVQEAWVPSQDTHHTQELLAVQGSLEVDPAQAGALVQRLCMRTPIYW 192


>gi|59858535 trefoil factor interactions(z) 1 [Homo sapiens]
          Length = 184

 Score = 34.3 bits (77), Expect = 0.070
 Identities = 35/159 (22%), Positives = 64/159 (40%), Gaps = 15/159 (9%)

Query: 40  VVVVVLIVVVIVGALLMGLHMSQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGS- 98
           ++V  L+V+ I G    G  +       ++  S      Q+ + +      TA  +I + 
Sbjct: 3   ILVAFLVVLTIFGIQSHGYEVFN-----IISPSNNGGNVQETVTIDNEK-NTAIINIHAG 56

Query: 99  --TGLVVYDYQQLLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAV 156
             +   ++DY+   IA +      C+I+K+  ++IP L  L   ++        QA   +
Sbjct: 57  SCSSTTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIY------EKQALDNM 110

Query: 157 PTSKLGQAEGRDAGSAPSGGDPAFLGMAVSTLCGEVPLY 195
            +SK    +     S     D   LG  +  LC  +PLY
Sbjct: 111 FSSKYTWVKYNPLESLIKDVDWFLLGSPIEKLCKHIPLY 149


>gi|169215507 PREDICTED: similar to hCG1732289 [Homo sapiens]
          Length = 490

 Score = 27.7 bits (60), Expect = 6.6
 Identities = 11/21 (52%), Positives = 19/21 (90%)

Query: 36 LLIVVVVVVLIVVVIVGALLM 56
          +++VVVVVV++VVV+V  ++M
Sbjct: 40 VMVVVVVVVMVVVVVVEVMVM 60



 Score = 27.7 bits (60), Expect = 6.6
 Identities = 11/21 (52%), Positives = 19/21 (90%)

Query: 36 LLIVVVVVVLIVVVIVGALLM 56
          +++VVVVVV++VVV+V  ++M
Sbjct: 59 VMVVVVVVVMVVVVVVEVMVM 79


>gi|190341084 HECT domain containing 2 isoform a [Homo sapiens]
          Length = 776

 Score = 27.7 bits (60), Expect = 6.6
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 6/69 (8%)

Query: 100 GLVVYDYQQLLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQME--CSLQAKPAVP 157
           GL VY+   L I + P    CCY   ++P  IPS + +   + N  ++  C +  + A  
Sbjct: 510 GLAVYNSITLDIRFPP----CCYKKLLSPPIIPSDQNIPVGICNVTVDDLCQIMPELAHG 565

Query: 158 TSKLGQAEG 166
            S+L   EG
Sbjct: 566 LSELLSHEG 574


>gi|17158025 RNA pseudouridylate synthase domain containing 1 [Homo
           sapiens]
          Length = 312

 Score = 27.7 bits (60), Expect = 6.6
 Identities = 18/65 (27%), Positives = 26/65 (40%)

Query: 128 PESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAFLGMAVST 187
           P S   L+ LT + H  ++ CS    P V     G+  GR+           +L +   T
Sbjct: 160 PVSKVLLKPLTGRTHQLRVHCSALGHPVVGDLTYGEVSGREDRPFRMMLHAFYLRIPTDT 219

Query: 188 LCGEV 192
            C EV
Sbjct: 220 ECVEV 224


>gi|16418451 hypothetical protein LOC116328 [Homo sapiens]
          Length = 427

 Score = 27.7 bits (60), Expect = 6.6
 Identities = 11/23 (47%), Positives = 16/23 (69%)

Query: 153 KPAVPTSKLGQAEGRDAGSAPSG 175
           +P +P SK  Q E  D+GS+P+G
Sbjct: 179 QPPIPRSKNDQWESEDSGSSPAG 201


>gi|239753040 PREDICTED: hypothetical protein XP_002345331 [Homo
           sapiens]
          Length = 244

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 19/78 (24%), Positives = 32/78 (41%), Gaps = 2/78 (2%)

Query: 109 LLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQMEC--SLQAKPAVPTSKLGQAEG 166
           L +   P  G    ++     S+PS+ +++    +   E   SL A P+     L     
Sbjct: 114 LAVMRAPVTGALITVVWCRERSLPSVRSVSLGAMSRDSESLLSLSASPSERLGLLSSCSP 173

Query: 167 RDAGSAPSGGDPAFLGMA 184
             AG+ P G  PA L ++
Sbjct: 174 SAAGAPPDGFSPASLSLS 191


>gi|239747598 PREDICTED: hypothetical protein XP_002347782 [Homo
           sapiens]
          Length = 244

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 19/78 (24%), Positives = 32/78 (41%), Gaps = 2/78 (2%)

Query: 109 LLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQMEC--SLQAKPAVPTSKLGQAEG 166
           L +   P  G    ++     S+PS+ +++    +   E   SL A P+     L     
Sbjct: 114 LAVMRAPVTGALITVVWCRERSLPSVRSVSLGAMSRDSESLLSLSASPSERLGLLSSCSP 173

Query: 167 RDAGSAPSGGDPAFLGMA 184
             AG+ P G  PA L ++
Sbjct: 174 SAAGAPPDGFSPASLSLS 191


>gi|239741463 PREDICTED: hypothetical protein XP_002342210 [Homo
           sapiens]
          Length = 244

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 19/78 (24%), Positives = 32/78 (41%), Gaps = 2/78 (2%)

Query: 109 LLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQMEC--SLQAKPAVPTSKLGQAEG 166
           L +   P  G    ++     S+PS+ +++    +   E   SL A P+     L     
Sbjct: 114 LAVMRAPVTGALITVVWCRERSLPSVRSVSLGAMSRDSESLLSLSASPSERLGLLSSCSP 173

Query: 167 RDAGSAPSGGDPAFLGMA 184
             AG+ P G  PA L ++
Sbjct: 174 SAAGAPPDGFSPASLSLS 191


>gi|145976946 hypothetical protein LOC653784 [Homo sapiens]
          Length = 158

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 12/25 (48%), Positives = 16/25 (64%)

Query: 152 AKPAVPTSKLGQAEGRDAGSAPSGG 176
           A  ++PTS + +  GRD GSA  GG
Sbjct: 93  AAVSLPTSSVPETRGRDKGSAALGG 117


>gi|27436867 slit and trk like 4 protein [Homo sapiens]
          Length = 837

 Score = 27.3 bits (59), Expect = 8.6
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 8/84 (9%)

Query: 12  SPPDYSAAPRGRFGIPCCPVHLK-------RLLIVVVVVVLIVVVIVGALLMGLHMSQKH 64
           S P  S AP   F  P  P+           +LI+ ++VVLI+ V V   L+   + +  
Sbjct: 588 SAPFTSPAPAITFTTPLGPIRSPPGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNK 647

Query: 65  TEMVLEMSIGAPE-AQQRLALSEH 87
              V    +G P+    +L L +H
Sbjct: 648 KPTVKHEGLGNPDCGSMQLQLRKH 671


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,787,417
Number of Sequences: 37866
Number of extensions: 319264
Number of successful extensions: 1180
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1066
Number of HSP's gapped (non-prelim): 114
length of query: 197
length of database: 18,247,518
effective HSP length: 97
effective length of query: 100
effective length of database: 14,574,516
effective search space: 1457451600
effective search space used: 1457451600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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