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Search of human proteins with 148806925
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
(690 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 1419 0.0
gi|6912464 latrophilin 2 precursor [Homo sapiens] 414 e-115
gi|163792198 latrophilin 3 precursor [Homo sapiens] 409 e-114
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 396 e-110
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 396 e-110
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 315 9e-86
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 299 7e-81
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 291 1e-78
gi|40807489 egf-like module containing, mucin-like, hormone rece... 291 1e-78
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 291 2e-78
gi|23397681 egf-like module containing, mucin-like, hormone rece... 269 7e-72
gi|23397693 egf-like module containing, mucin-like, hormone rece... 269 7e-72
gi|23397691 egf-like module containing, mucin-like, hormone rece... 269 7e-72
gi|23397689 egf-like module containing, mucin-like, hormone rece... 269 7e-72
gi|23397687 egf-like module containing, mucin-like, hormone rece... 269 7e-72
gi|23397685 egf-like module containing, mucin-like, hormone rece... 269 7e-72
gi|23397683 egf-like module containing, mucin-like, hormone rece... 269 7e-72
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 213 5e-55
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 205 1e-52
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 190 4e-48
gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 181 3e-45
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 171 2e-42
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 158 1e-38
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 158 1e-38
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] 158 1e-38
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] 158 1e-38
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 158 1e-38
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 158 2e-38
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 156 7e-38
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho... 153 4e-37
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 1419 bits (3672), Expect = 0.0
Identities = 690/690 (100%), Positives = 690/690 (100%)
Query: 1 MKRLPLLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDN 60
MKRLPLLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDN
Sbjct: 1 MKRLPLLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDN 60
Query: 61 ECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNV 120
ECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNV
Sbjct: 61 ECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNV 120
Query: 121 CIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTI 180
CIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTI
Sbjct: 121 CIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTI 180
Query: 181 SAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSF 240
SAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSF
Sbjct: 181 SAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSF 240
Query: 241 QKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFV 300
QKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFV
Sbjct: 241 QKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFV 300
Query: 301 YYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHR 360
YYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHR
Sbjct: 301 YYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHR 360
Query: 361 KVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIG 420
KVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIG
Sbjct: 361 KVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIG 420
Query: 421 IKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVG 480
IKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVG
Sbjct: 421 IKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVG 480
Query: 481 INTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLS 540
INTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLS
Sbjct: 481 INTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLS 540
Query: 541 PAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHT 600
PAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHT
Sbjct: 541 PAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHT 600
Query: 601 AGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFI 660
AGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFI
Sbjct: 601 AGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFI 660
Query: 661 FLFLCVLSRKIQEEYYRLFKNVPCCFGCLR 690
FLFLCVLSRKIQEEYYRLFKNVPCCFGCLR
Sbjct: 661 FLFLCVLSRKIQEEYYRLFKNVPCCFGCLR 690
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 414 bits (1063), Expect = e-115
Identities = 222/575 (38%), Positives = 337/575 (58%), Gaps = 9/575 (1%)
Query: 121 CIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTI 180
C + +N+ KIRS + +L E+ +++ + D+ + + ++ + +L + +
Sbjct: 521 CTSHWVNQLAQKIRSGENAASLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQEL 580
Query: 181 --SAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQ 238
S KD+ S V TV+N ++ + W ++ + + T L+ T+E+ ++
Sbjct: 581 KPSEKDSAGRSYNKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLAD 640
Query: 239 SFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPH---MNMDGDYINIFPKRKAAYDSNGNV 295
+ + T + +I L+V + + G I + NG
Sbjct: 641 NLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAGSSIQLSANTVKQNSRNGLA 700
Query: 296 AVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITF 355
+ F+ Y+S+G LS+ + + ++ V S VISVS++ +Y + + F
Sbjct: 701 KLVFIIYRSLGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLF 760
Query: 356 TLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSS 415
TL H + + + C+FWNYS TM G WS++GC+L +N+T T+C C+HLT+FAILM+
Sbjct: 761 TLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAH 820
Query: 416 GPSIGIKD---YNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFL 472
I KD +LT IT +GI+ISL+CLAICIFTF FF +QS R TIHKNLC +LF+
Sbjct: 821 R-EIAYKDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFI 879
Query: 473 AELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKN 532
AE +FL+GI+ + C I AGLLH+FFLAAFAWMC+EG+ LYL++V V ++ K
Sbjct: 880 AEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKY 939
Query: 533 FYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVI 592
+Y+ GYL PA VVG SAA+ Y+ YGT K CWL +N FIWSFIGP IIL+N++ +
Sbjct: 940 YYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVIT 999
Query: 593 IYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVS 652
+ K+ +H+ LKP+ S ENI+S GA ALL LLG TW FG+L + ++V AYLFT+
Sbjct: 1000 LCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIF 1059
Query: 653 NAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFG 687
NAFQG+FIF+F C L +K+++EY + F++ CC G
Sbjct: 1060 NAFQGVFIFIFHCALQKKVRKEYGKCFRHSYCCGG 1094
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 409 bits (1051), Expect = e-114
Identities = 230/598 (38%), Positives = 347/598 (58%), Gaps = 33/598 (5%)
Query: 121 CIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGY--KNN 178
C + +N K++S + + +E+ + L+ DI + + + LL +N
Sbjct: 550 CSSPWVNHITQKLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNL 609
Query: 179 TISAKDTLSNST-------------LTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKL 225
T KD+ + S + V+TVNN +Q W L+ + + T L
Sbjct: 610 TPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATML 669
Query: 226 MHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSY-NMKHIHPHMNMD-GDYINIFP 283
+HTVE++ ++ + KT N+ +I L+V + N++ + NM G I +
Sbjct: 670 LHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNLEDLKFPENMGHGSTIQLSA 729
Query: 284 KRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSN 343
NG + VAFV Y ++GP LS+ + + ++ V S VI+ +++
Sbjct: 730 NTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEALSTNHSVIVNSPVITAAINKE 789
Query: 344 -PPTLYELEKITFTLSHRKVTDR-YRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSC 401
+Y + + FT+ H K ++ + C+FW+YS TM G WS++GC L +N+THT+C
Sbjct: 790 FSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTC 849
Query: 402 RCNHLTHFAILMSSGP---SIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQST 458
CNHLT+FA+LM+ S + D +L IT +GI++SL+CL ICIFTF FF +QS
Sbjct: 850 SCNHLTNFAVLMAHVEVKHSDAVHDL-LLDVITWVGILLSLVCLLICIFTFCFFRGLQSD 908
Query: 459 RTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLI 518
R TIHKNLC SLF+AEL+FL+GIN + C++ A LLH+FFLAAF WM +EG+ LY++
Sbjct: 909 RNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIM 968
Query: 519 VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPA 578
+V V ++ K FY+ GY PA++V SAA+ YR YGT KVCWL + FIWSFIGPA
Sbjct: 969 LVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPA 1028
Query: 579 CLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFEN---------IRSCARGALALLFLLGT 629
LII++N++ G+ +YK+F HTA LKPE C +N I+S GA+ALL LLG
Sbjct: 1029 TLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGL 1088
Query: 630 TWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFG 687
TW FG++++ ++V+ AYLFT+ N+ QGMFIF+F CVL +K+++EY + + CC G
Sbjct: 1089 TWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLR-THCCSG 1145
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 396 bits (1018), Expect = e-110
Identities = 216/592 (36%), Positives = 341/592 (57%), Gaps = 32/592 (5%)
Query: 121 CIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLL------- 173
C + +N+ KI+S + + E+ R++ + D+ + ++++ + +L
Sbjct: 532 CTSPWVNQVAQKIKSGENAANIASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQAL 591
Query: 174 --------GYKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKL 225
G N + ++ + V+TV+N ++ + W ++ + T L
Sbjct: 592 RPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATML 651
Query: 226 MHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSYNM-------KHIHPHMNMDGDY 278
+ +E+ ++ + ++ F ++ L+V ++ + +P N
Sbjct: 652 LDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKNS---- 707
Query: 279 INIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDN----SEEEERVISS 334
I + K NG V V F+ Y ++G L S++N +K V S
Sbjct: 708 IQLSAKTIKQNSRNGVVKVVFILYNNLG-LFLSTENATVKLAGEAGPGGPGGASLVVNSQ 766
Query: 335 VISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYS 394
VI+ S++ ++ ++ + FT++H + + + + C+FWNYS +M G WS++GC L S
Sbjct: 767 VIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVES 826
Query: 395 NETHTSCRCNHLTHFAILMSSGPSI-GIKDYNILTRITQLGIIISLICLAICIFTFWFFS 453
N+THT+C C+HLT+FA+LM+ G + +L+ IT +GI+ISL+CLAICI TF F
Sbjct: 827 NKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLR 886
Query: 454 EIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGI 513
+Q+ R TIHKNLC +LFLAEL+FLVGI+ ++ C I AGLLHYFFLAAF+W+C+EG+
Sbjct: 887 GLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGV 946
Query: 514 HLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWS 573
HLYL++V V ++ K +Y+ GY PA+VVG +AA+ YR YGT K CWL +N FIWS
Sbjct: 947 HLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS 1006
Query: 574 FIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIF 633
FIGP +I+VNL+ V ++K+ R ++ LKP+ S +NI+S A GA+ALLFLLG TW F
Sbjct: 1007 FIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAF 1066
Query: 634 GVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCC 685
G+L + SVV AYLFT NAFQG+FIF+F C L +K+ +EY + ++ CC
Sbjct: 1067 GLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCC 1118
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 396 bits (1018), Expect = e-110
Identities = 216/592 (36%), Positives = 341/592 (57%), Gaps = 32/592 (5%)
Query: 121 CIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLL------- 173
C + +N+ KI+S + + E+ R++ + D+ + ++++ + +L
Sbjct: 527 CTSPWVNQVAQKIKSGENAANIASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQAL 586
Query: 174 --------GYKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKL 225
G N + ++ + V+TV+N ++ + W ++ + T L
Sbjct: 587 RPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATML 646
Query: 226 MHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSYNM-------KHIHPHMNMDGDY 278
+ +E+ ++ + ++ F ++ L+V ++ + +P N
Sbjct: 647 LDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKNS---- 702
Query: 279 INIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDN----SEEEERVISS 334
I + K NG V V F+ Y ++G L S++N +K V S
Sbjct: 703 IQLSAKTIKQNSRNGVVKVVFILYNNLG-LFLSTENATVKLAGEAGPGGPGGASLVVNSQ 761
Query: 335 VISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYS 394
VI+ S++ ++ ++ + FT++H + + + + C+FWNYS +M G WS++GC L S
Sbjct: 762 VIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVES 821
Query: 395 NETHTSCRCNHLTHFAILMSSGPSI-GIKDYNILTRITQLGIIISLICLAICIFTFWFFS 453
N+THT+C C+HLT+FA+LM+ G + +L+ IT +GI+ISL+CLAICI TF F
Sbjct: 822 NKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLR 881
Query: 454 EIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGI 513
+Q+ R TIHKNLC +LFLAEL+FLVGI+ ++ C I AGLLHYFFLAAF+W+C+EG+
Sbjct: 882 GLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGV 941
Query: 514 HLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWS 573
HLYL++V V ++ K +Y+ GY PA+VVG +AA+ YR YGT K CWL +N FIWS
Sbjct: 942 HLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS 1001
Query: 574 FIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIF 633
FIGP +I+VNL+ V ++K+ R ++ LKP+ S +NI+S A GA+ALLFLLG TW F
Sbjct: 1002 FIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAF 1061
Query: 634 GVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCC 685
G+L + SVV AYLFT NAFQG+FIF+F C L +K+ +EY + ++ CC
Sbjct: 1062 GLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCC 1113
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 315 bits (807), Expect = 9e-86
Identities = 222/695 (31%), Positives = 335/695 (48%), Gaps = 109/695 (15%)
Query: 6 LLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGF-SGNGVTI-------CE 57
LL +F + + T +C K P PNA C + N C CN G+ SG+G + C
Sbjct: 13 LLSLFGAVTQKTKT-SCAKCP--PNASC-VNN--THCTCNHGYTSGSGQKLFTFPLETCN 66
Query: 58 DDNECGN-LTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCH 116
D NEC + CG NA C N EGS+YC CVPG+R S ++F ++ C + ++
Sbjct: 67 DINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSK-- 124
Query: 117 LDNVCIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYK 176
K L KI E + Q ++R EI + ++++L +
Sbjct: 125 ------TTEGRKELQKIVDKFESLLTNQTLWRTEGRQ----------EISSTATTIL--R 166
Query: 177 NNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRI 236
+ +T + +K N+ V +T + D S + +L M++++ +R
Sbjct: 167 DVESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMD---IRC 223
Query: 237 SQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVA 296
S Q T+ G A
Sbjct: 224 SDIIQGDTQ-----------------------------------------------GPSA 236
Query: 297 VAFVYYKSIGPLLSSS--DNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKIT 354
+AF+ Y S+G +++++ + K Q Y NS+ I +VS+S + +T
Sbjct: 237 IAFISYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLS---------KSVT 287
Query: 355 FTLSHRKVTDRYRSL-CAFWNYSPDTMNGS-WSSEGCELTYSNETHTSCRCNHLTHFAIL 412
T H K+T + + C +W T GS WS +GC L + N++HT C C+HL+ FA+L
Sbjct: 288 LTFQHVKMTPSTKKVFCVYWK---STGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVL 344
Query: 413 MSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFL 472
M+ ++ +LT IT +G+ +SL+CL + TF I++T T++H L LFL
Sbjct: 345 MALTSQ---EEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFL 401
Query: 473 AELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLY-----LIVVGVIYNKG 527
A L+FLVGI+ K+ CSIIAG LHY +LAAF WM +EG+HL+ L VV
Sbjct: 402 AHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINR 461
Query: 528 FLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLL 587
+ + GY PAV V SAA YGT CWL + F+WSF+GP C I NL+
Sbjct: 462 LMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLV 521
Query: 588 AFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAY 647
F ++ + + R + L EVS +N R A A A LF+LG TW G+L V A+ V AY
Sbjct: 522 LFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAY 581
Query: 648 LFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
LFT+ N+ QG FIFL C+LS+++Q++Y + F+ +
Sbjct: 582 LFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREI 616
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 299 bits (765), Expect = 7e-81
Identities = 212/698 (30%), Positives = 335/698 (47%), Gaps = 72/698 (10%)
Query: 27 CLPNAKCEIRNGIEACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTE 79
C N+ C AC CN GFS I C+D NEC ++ SCG+ ++C NTE
Sbjct: 30 CPQNSSCV---NATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 80 GSYYCMCVPGFRSSSNQDRFITNDGTVCIE-----NVNANCHLDNVCIAANINKTLTKIR 134
GSY C+C PG+ S F C + + C VC + + R
Sbjct: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNT-VGSYSCRCR 145
Query: 135 SIKEPVALLQEVYRNSVTD-------LSPTDIITY-IEILAESSSLLGYKNNTISAKDTL 186
+P + +++V + P + + + + LG + T SA+ T+
Sbjct: 146 PGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTI 205
Query: 187 SNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKT--T 244
N +K V+ ++ V + L+ R T+L+ +E +++S K T
Sbjct: 206 QN-----VIKLVDELMEAPGDV--EALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFT 258
Query: 245 EFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKS 304
++T++ L + N+ M + + A + G + ++
Sbjct: 259 YISPSNTELTLMIQERGDKNVT-----MGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 313
Query: 305 IGPLLSSSDNFLLKPQNYDNSEEEE--------RVISSVISVSMSSNPPTLYELEK-ITF 355
+ LL+++ L + + E E R +S+V S+ +S N EL I F
Sbjct: 314 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN--NTKELNSPILF 371
Query: 356 TLSHRKVTD----------------RYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHT 399
SH + +D R LCAFW D G W++EGC++ S T
Sbjct: 372 AFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDR-GGHWATEGCQVLGSKNGST 430
Query: 400 SCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTR 459
+C+C+HL+ FAILM+ ++D+ LT IT++G+ +SL CL +CI TF IQ +R
Sbjct: 431 TCQCSHLSSFAILMAH---YDVEDWK-LTLITRVGLALSLFCLLLCILTFLLVRPIQGSR 486
Query: 460 TTIHKNLCCSLFLAELVFLVGINTNTNK--LFCSIIAGLLHYFFLAAFAWMCIEGIHLYL 517
TTIH +LC LF+ +FL GI + L C ++AGLLHY FLAAF WM +EG+ LY
Sbjct: 487 TTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYF 546
Query: 518 IVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGP 577
+VV V +G + + GY P ++VG SAA+ + YG + CWL E F+WSF+GP
Sbjct: 547 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 606
Query: 578 ACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLH 637
IIL N + F ++K+ + + + P++ + R+ A+A LFLLG TW+FG+
Sbjct: 607 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 666
Query: 638 VVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEY 675
S+V Y+FT+ N QG F++L C+L++K++EEY
Sbjct: 667 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY 704
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 291 bits (746), Expect = 1e-78
Identities = 209/702 (29%), Positives = 328/702 (46%), Gaps = 104/702 (14%)
Query: 16 CSYTQNCT--KTPCLPNAKCEIRNGIEACYCNMGF-------SGNGVTICEDDNECGNLT 66
C+ CT + PC + C G C C G+ +G T+CED +EC +
Sbjct: 158 CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQ 217
Query: 67 QSCGENANCTNTEGSYYCMCVPGFRSS----SNQDRFITNDGTVCIENVNANCHLDNVCI 122
C + C NT GSY C C PG++ +NQ + D T H
Sbjct: 218 HQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVH------ 271
Query: 123 AANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISA 182
++TL++ + + V DL G + T SA
Sbjct: 272 ----SQTLSR--------------FFDKVQDL-------------------GRDSKTSSA 294
Query: 183 KDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQK 242
+ T+ N +K V+ ++ V + L+ R T+L+ +E +++S K
Sbjct: 295 EVTIQN-----VIKLVDELMEAPGDV--EALAPPVRHLIATQLLSNLEDIMRILAKSLPK 347
Query: 243 T--TEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFV 300
T ++T++ L + N+ M + + A + G +
Sbjct: 348 GPFTYISPSNTELTLMIQERGDKNVT-----MGQSSARMKLNWAVAAGAEDPGPAVAGIL 402
Query: 301 YYKSIGPLLSSSDNFLLKPQNYDNSEEEE--------RVISSVISVSMSSNPPTLYELEK 352
+++ LL+++ L + + E E R +S+V S+ +S N EL
Sbjct: 403 SIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN--NTKELNS 460
Query: 353 -ITFTLSHRKVTD----------------RYRSLCAFWNYSPDTMNGSWSSEGCELTYSN 395
I F SH + +D R LCAFW D G W++EGC++ S
Sbjct: 461 PILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDR-GGHWATEGCQVLGSK 519
Query: 396 ETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEI 455
T+C+C+HL+ FAILM+ ++D+ LT IT++G+ +SL CL +CI TF I
Sbjct: 520 NGSTTCQCSHLSSFAILMAH---YDVEDWK-LTLITRVGLALSLFCLLLCILTFLLVRPI 575
Query: 456 QSTRTTIHKNLCCSLFLAELVFLVGINTNTNK--LFCSIIAGLLHYFFLAAFAWMCIEGI 513
Q +RTTIH +LC LF+ +FL GI + L C ++AGLLHY FLAAF WM +EG+
Sbjct: 576 QGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGL 635
Query: 514 HLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWS 573
LY +VV V +G + + GY P ++VG SAA+ + YG + CWL E F+WS
Sbjct: 636 ELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWS 695
Query: 574 FIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIF 633
F+GP IIL N + F ++K+ + + + P++ + R+ A+A LFLLG TW+F
Sbjct: 696 FLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVF 755
Query: 634 GVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEY 675
G+ S+V Y+FT+ N QG F++L C+L++K++EEY
Sbjct: 756 GLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY 797
Score = 59.3 bits (142), Expect = 1e-08
Identities = 33/88 (37%), Positives = 42/88 (47%), Gaps = 10/88 (11%)
Query: 27 CLPNAKCEIRNGIEACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTE 79
C N+ C AC CN GFS I C+D NEC ++ SCG+ ++C NTE
Sbjct: 30 CPQNSSCV---NATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 80 GSYYCMCVPGFRSSSNQDRFITNDGTVC 107
GSY C+C PG+ S F C
Sbjct: 87 GSYDCVCSPGYEPVSGAKTFKNESENTC 114
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 11/109 (10%)
Query: 23 TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTICEDDNECGNLTQSCGENA 73
+K C + C G C C+ G F C+D +EC + C
Sbjct: 72 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 131
Query: 74 NCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVCI 122
C NT GSY C C+PGF+ +D + D C N CH C+
Sbjct: 132 TCVNTLGSYTCQCLPGFKFIP-EDPKVCTDVNECTSGQNP-CHSSTHCL 178
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 291 bits (745), Expect = 1e-78
Identities = 215/695 (30%), Positives = 333/695 (47%), Gaps = 63/695 (9%)
Query: 27 CLPNAKCEIRNGIEACYCNMGFSGNGVTI--------CEDDNECGNLTQSCGENANCTNT 78
C +A C G +C+CN GF + + CED +EC T+ C N+ CTNT
Sbjct: 182 CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCPINSTCTNT 238
Query: 79 EGSYYCMCVPGFRSSSNQDRFITNDGTVC-----IENVNANCHLDNVCIAANINKTLTKI 133
GSY+C C PGF S+ Q F T+ G C + C +++C A + + I
Sbjct: 239 PGSYFCTCHPGFAPSNGQLNF-TDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
Query: 134 R--------SIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESS-------SLLGYKNN 178
S K+ Q V D+ P + I+ E + S NN
Sbjct: 298 AGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDN--KQIQQCQEGTAVKPAYVSFCAQINN 355
Query: 179 TISAKDTL--SNSTLTEFVKTVNNFVQ-RDTFVVWDKLSVNHRRTHLTKLMHTVEQATLR 235
S D + + +T+ T +FV W K + + T + +VE TL
Sbjct: 356 IFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLA 415
Query: 236 I--SQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMD----GDYINIFPKRKAAY 289
S T T DI KV N + ++ +D GD + I
Sbjct: 416 SFWKPSANITPAVRTEYLDIESKVI-----NKECSEENVTLDLVAKGDKMKIGCSTIEES 470
Query: 290 DSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQ-NYDNSEEEERVISSVISVSMSSNPPTLY 348
+S VAFV + + +L ++ F Q SE + ++ S V+ M+ +
Sbjct: 471 ESTETTGVAFVSFVGMESVL--NERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGF 528
Query: 349 ELEKITFTLSHRKVTDRY-RSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLT 407
+ I +TL + + ++ R +C W S D G W+S GC + ++ET+T C CN +
Sbjct: 529 S-DPIIYTLENIQPKQKFERPICVSW--STDVKGGRWTSFGCVILEASETYTICSCNQMA 585
Query: 408 HFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLC 467
+ A++M+SG D+++ I+ +GIIISL+CL + I TF I++ T +H +LC
Sbjct: 586 NLAVIMASGEL--TMDFSLYI-ISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLC 642
Query: 468 CSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKG 527
L LA+ +FL GI+ NK+ C+IIAG LHY FLA F WM +E + L+L+V +
Sbjct: 643 VCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNY 702
Query: 528 FLHKNFYI-----FGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLII 582
F +N + FGY P +VV SA++ + YG CWL+TE FIWSF+GP C +I
Sbjct: 703 FSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVI 762
Query: 583 LVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHAS 642
++N L ++ + + + + EVS ++ R A A LF+LG +W+ G+ + +
Sbjct: 763 VINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVA 822
Query: 643 VVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYR 677
V AYLFT+ N+ QG FIFL C+L+ +++EEY R
Sbjct: 823 GVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKR 857
Score = 65.9 bits (159), Expect = 1e-10
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 13/119 (10%)
Query: 15 NCSYTQNC-TKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENA 73
+C+ C T + C ++ C G +C C +GF T CED +EC + ++C E+A
Sbjct: 129 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNST-CEDVDECAD-PRACPEHA 186
Query: 74 NCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCH-LDNVCIAANINKTLT 131
C NT G+Y C C PGF SSS G + + + A+C +D IN T T
Sbjct: 187 TCNNTVGNYSCFCNPGFESSS---------GHLSFQGLKASCEDIDECTEMCPINSTCT 236
Score = 56.2 bits (134), Expect = 1e-07
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 10/110 (9%)
Query: 21 NCT-KTPCLPNAKCEIRNGIEACYCNMGF-SGNGVTI-------CEDDNECGNLTQSCGE 71
NC T C A C C C GF S NG C+D +EC Q CG
Sbjct: 34 NCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGP 93
Query: 72 NANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVC 121
N++C N G Y C C+ GF S + D G ++N C +VC
Sbjct: 94 NSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDIN-ECLTSSVC 142
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 291 bits (744), Expect = 2e-78
Identities = 208/704 (29%), Positives = 330/704 (46%), Gaps = 78/704 (11%)
Query: 23 TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTICEDDNECGNLTQSCGENA 73
+K C + C G C C+ G F C+D +EC + C
Sbjct: 72 SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG 131
Query: 74 NCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIE-----NVNANCHLDNVCIAANINK 128
C NT GSY C C+PGF+ FI D VC + + C VC +
Sbjct: 132 TCVNTLGSYTCQCLPGFK-------FIPEDPKVCTDVDECSSGQHQCDSSTVCFNT-VGS 183
Query: 129 TLTKIRSIKEPVALLQEVYRNSVTD-------LSPTDIITY-IEILAESSSLLGYKNNTI 180
+ R +P + +++V + P + + + + LG + T
Sbjct: 184 YSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTS 243
Query: 181 SAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSF 240
SA+ T+ N +K V+ ++ V + L+ R T+L+ +E +++S
Sbjct: 244 SAEVTIQN-----VIKLVDELMEAPGDV--EALAPPVRHLIATQLLSNLEDIMRILAKSL 296
Query: 241 QKT--TEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVA 298
K T ++T++ L + N+ M + + A + G
Sbjct: 297 PKGPFTYISPSNTELTLMIQERGDKNVT-----MGQSSARMKLNWAVAAGAEDPGPAVAG 351
Query: 299 FVYYKSIGPLLSSSDNFLLKPQNYDNSEEEE--------RVISSVISVSMSSNPPTLYEL 350
+ +++ LL+++ L + + E E R +S+V S+ +S N EL
Sbjct: 352 ILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN--NTKEL 409
Query: 351 EK-ITFTLSHRKVTD----------------RYRSLCAFWNYSPDTMNGSWSSEGCELTY 393
I F SH + +D R LCAFW D G W++EGC++
Sbjct: 410 NSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDR-GGHWATEGCQVLG 468
Query: 394 SNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFS 453
S T+C+C+HL+ FAILM+ ++D+ LT IT++G+ +SL CL +CI TF
Sbjct: 469 SKNGSTTCQCSHLSSFAILMAH---YDVEDWK-LTLITRVGLALSLFCLLLCILTFLLVR 524
Query: 454 EIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNK--LFCSIIAGLLHYFFLAAFAWMCIE 511
IQ +RTTIH +LC LF+ +FL GI + L C ++AGLLHY FLAAF WM +E
Sbjct: 525 PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLE 584
Query: 512 GIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFI 571
G+ LY +VV V +G + + GY P ++VG SAA+ + YG + CWL E F+
Sbjct: 585 GLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL 644
Query: 572 WSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTW 631
WSF+GP IIL N + F ++K+ + + + P++ + R+ A+A LFLLG TW
Sbjct: 645 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW 704
Query: 632 IFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEY 675
+FG+ S+V Y+FT+ N QG F++L C+L++K++EEY
Sbjct: 705 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY 748
Score = 59.3 bits (142), Expect = 1e-08
Identities = 33/88 (37%), Positives = 42/88 (47%), Gaps = 10/88 (11%)
Query: 27 CLPNAKCEIRNGIEACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTE 79
C N+ C AC CN GFS I C+D NEC ++ SCG+ ++C NTE
Sbjct: 30 CPQNSSCV---NATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 80 GSYYCMCVPGFRSSSNQDRFITNDGTVC 107
GSY C+C PG+ S F C
Sbjct: 87 GSYDCVCSPGYEPVSGAKTFKNESENTC 114
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 269 bits (687), Expect = 7e-72
Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)
Query: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390
++S VIS +S+N T +TFT SHR V R + LC FW + + G W++ GC
Sbjct: 444 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 501
Query: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449
+ +T T CRC HL+ FA+LM+ +++ + +LT IT +G+ +SL+CL + TF
Sbjct: 502 TIGTRDTSTICRCTHLSSFAVLMA---HYDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 558
Query: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509
IQ+T T++H L LFLA L+FLV I+ +K+ CSIIAG LHY +LA WM
Sbjct: 559 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 618
Query: 510 IEGIHLY-----LIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564
+E ++L+ L VV F+ K + GY PAV V SAA YGT CWL
Sbjct: 619 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 678
Query: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624
E FIW F+GP C I VNL+ F V ++ + + L EVS N R A A A L
Sbjct: 679 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 738
Query: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
F+LG TW G+L V A+ V AYLFT+ N+ QG+FIFL C+LS++++E+Y + K +
Sbjct: 739 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 796
Score = 60.8 bits (146), Expect = 4e-09
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 41 ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93
AC CN GFS I C+D NEC L++ SCG+ ++C NTEGSY C+C PG+
Sbjct: 44 ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
Query: 94 SNQDRFITNDGTVC 107
S F C
Sbjct: 104 SGAKTFKNESENTC 117
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
Query: 16 CSYTQNCT--KTPCLPNAKCEIRNGIEACYCNMGF-------SGNGVTICEDDNECGNLT 66
C+ CT + PC + C G C C G+ +G T+CED +EC +
Sbjct: 161 CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQ 220
Query: 67 QSCGENANCTNTEGSYYCMCVPGFR 91
C + C NT GSY C C PG++
Sbjct: 221 HQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 53.9 bits (128), Expect = 5e-07
Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 14/127 (11%)
Query: 8 VVFSTLLNCSYTQNC---TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTI 55
++ + + C C +K C + C G C C+ G F
Sbjct: 57 IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT 116
Query: 56 CEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANC 115
C+D +EC + C C NT GSY C C+PGF+ + T D C N C
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCT-DVNECTSGQNP-C 174
Query: 116 HLDNVCI 122
H C+
Sbjct: 175 HSSTHCL 181
Score = 48.1 bits (113), Expect = 3e-05
Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 9/114 (7%)
Query: 16 CSYTQNCTKTP--CLPNAKCEIRNGIEACYCNMGFS--GNGVTICEDDNECGNLTQSCGE 71
C C + P C C G C C GF +C D NEC + C
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHS 176
Query: 72 NANCTNTEGSYYCMCVPGFR----SSSNQDRFITNDGTVCIENVNANCHLDNVC 121
+ +C N GSY C C PG++ S + + + D C + C VC
Sbjct: 177 STHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQH-QCDSSTVC 229
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 269 bits (687), Expect = 7e-72
Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)
Query: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390
++S VIS +S+N T +TFT SHR V R + LC FW + + G W++ GC
Sbjct: 340 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 397
Query: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449
+ +T T CRC HL+ FA+LM+ +++ + +LT IT +G+ +SL+CL + TF
Sbjct: 398 TIGTRDTSTICRCTHLSSFAVLMAH---YDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 454
Query: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509
IQ+T T++H L LFLA L+FLV I+ +K+ CSIIAG LHY +LA WM
Sbjct: 455 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 514
Query: 510 IEGIHLYLI-----VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564
+E ++L+L VV F+ K + GY PAV V SAA YGT CWL
Sbjct: 515 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 574
Query: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624
E FIW F+GP C I VNL+ F V ++ + + L EVS N R A A A L
Sbjct: 575 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 634
Query: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
F+LG TW G+L V A+ V AYLFT+ N+ QG+FIFL C+LS++++E+Y + K +
Sbjct: 635 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 692
Score = 60.8 bits (146), Expect = 4e-09
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 41 ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93
AC CN GFS I C+D NEC L++ SCG+ ++C NTEGSY C+C PG+
Sbjct: 44 ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
Query: 94 SNQDRFITNDGTVC 107
S F C
Sbjct: 104 SGAKTFKNESENTC 117
Score = 46.2 bits (108), Expect = 1e-04
Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 8 VVFSTLLNCSYTQNC---TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTI 55
++ + + C C +K C + C G C C+ G F
Sbjct: 57 IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT 116
Query: 56 CEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFR 91
C+D +EC + C + C NT GSY C C PG++
Sbjct: 117 CQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 152
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 269 bits (687), Expect = 7e-72
Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)
Query: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390
++S VIS +S+N T +TFT SHR V R + LC FW + + G W++ GC
Sbjct: 384 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 441
Query: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449
+ +T T CRC HL+ FA+LM+ +++ + +LT IT +G+ +SL+CL + TF
Sbjct: 442 TIGTRDTSTICRCTHLSSFAVLMAH---YDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 498
Query: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509
IQ+T T++H L LFLA L+FLV I+ +K+ CSIIAG LHY +LA WM
Sbjct: 499 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 558
Query: 510 IEGIHLYLI-----VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564
+E ++L+L VV F+ K + GY PAV V SAA YGT CWL
Sbjct: 559 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 618
Query: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624
E FIW F+GP C I VNL+ F V ++ + + L EVS N R A A A L
Sbjct: 619 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 678
Query: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
F+LG TW G+L V A+ V AYLFT+ N+ QG+FIFL C+LS++++E+Y + K +
Sbjct: 679 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 736
Score = 60.8 bits (146), Expect = 4e-09
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 41 ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93
AC CN GFS I C+D NEC L++ SCG+ ++C NTEGSY C+C PG+
Sbjct: 44 ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
Query: 94 SNQDRFITNDGTVC 107
S F C
Sbjct: 104 SGAKTFKNESENTC 117
Score = 50.1 bits (118), Expect = 7e-06
Identities = 27/107 (25%), Positives = 41/107 (38%), Gaps = 12/107 (11%)
Query: 8 VVFSTLLNCSYTQNC---TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTI 55
++ + + C C +K C + C G C C+ G F
Sbjct: 57 IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT 116
Query: 56 CEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITN 102
C+D +EC + C C NT GSY C C+PGF+ + T+
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTD 163
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 16 CSYTQNCTKTP--CLPNAKCEIRNGIEACYCNMGFS--GNGVTICEDDNECGNLTQSCGE 71
C C + P C C G C C GF +C D +EC + C
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDS 176
Query: 72 NANCTNTEGSYYCMCVPGFR 91
+ C NT GSY C C PG++
Sbjct: 177 STVCFNTVGSYSCRCRPGWK 196
>gi|23397689 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform e [Homo sapiens]
Length = 812
Score = 269 bits (687), Expect = 7e-72
Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)
Query: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390
++S VIS +S+N T +TFT SHR V R + LC FW + + G W++ GC
Sbjct: 433 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 490
Query: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449
+ +T T CRC HL+ FA+LM+ +++ + +LT IT +G+ +SL+CL + TF
Sbjct: 491 TIGTRDTSTICRCTHLSSFAVLMA---HYDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 547
Query: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509
IQ+T T++H L LFLA L+FLV I+ +K+ CSIIAG LHY +LA WM
Sbjct: 548 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 607
Query: 510 IEGIHLY-----LIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564
+E ++L+ L VV F+ K + GY PAV V SAA YGT CWL
Sbjct: 608 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 667
Query: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624
E FIW F+GP C I VNL+ F V ++ + + L EVS N R A A A L
Sbjct: 668 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 727
Query: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
F+LG TW G+L V A+ V AYLFT+ N+ QG+FIFL C+LS++++E+Y + K +
Sbjct: 728 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 785
Score = 60.8 bits (146), Expect = 4e-09
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 41 ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93
AC CN GFS I C+D NEC L++ SCG+ ++C NTEGSY C+C PG+
Sbjct: 44 ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
Query: 94 SNQDRFITNDGTVC 107
S F C
Sbjct: 104 SGAKTFKNESENTC 117
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
Query: 16 CSYTQNCT--KTPCLPNAKCEIRNGIEACYCNMGF-------SGNGVTICEDDNECGNLT 66
C+ CT + PC + C G C C G+ +G T+CED +EC +
Sbjct: 161 CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQ 220
Query: 67 QSCGENANCTNTEGSYYCMCVPGFR 91
C + C NT GSY C C PG++
Sbjct: 221 HQCDSSTVCFNTVGSYSCRCRPGWK 245
Score = 53.9 bits (128), Expect = 5e-07
Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 14/127 (11%)
Query: 8 VVFSTLLNCSYTQNC---TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTI 55
++ + + C C +K C + C G C C+ G F
Sbjct: 57 IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT 116
Query: 56 CEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANC 115
C+D +EC + C C NT GSY C C+PGF+ + T D C N C
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCT-DVNECTSGQNP-C 174
Query: 116 HLDNVCI 122
H C+
Sbjct: 175 HSSTHCL 181
Score = 48.1 bits (113), Expect = 3e-05
Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 9/114 (7%)
Query: 16 CSYTQNCTKTP--CLPNAKCEIRNGIEACYCNMGFS--GNGVTICEDDNECGNLTQSCGE 71
C C + P C C G C C GF +C D NEC + C
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHS 176
Query: 72 NANCTNTEGSYYCMCVPGFR----SSSNQDRFITNDGTVCIENVNANCHLDNVC 121
+ +C N GSY C C PG++ S + + + D C + C VC
Sbjct: 177 STHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQH-QCDSSTVC 229
>gi|23397687 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform d [Homo sapiens]
Length = 681
Score = 269 bits (687), Expect = 7e-72
Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)
Query: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390
++S VIS +S+N T +TFT SHR V R + LC FW + + G W++ GC
Sbjct: 302 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 359
Query: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449
+ +T T CRC HL+ FA+LM+ +++ + +LT IT +G+ +SL+CL + TF
Sbjct: 360 TIGTRDTSTICRCTHLSSFAVLMAH---YDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 416
Query: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509
IQ+T T++H L LFLA L+FLV I+ +K+ CSIIAG LHY +LA WM
Sbjct: 417 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 476
Query: 510 IEGIHLYLI-----VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564
+E ++L+L VV F+ K + GY PAV V SAA YGT CWL
Sbjct: 477 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 536
Query: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624
E FIW F+GP C I VNL+ F V ++ + + L EVS N R A A A L
Sbjct: 537 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 596
Query: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
F+LG TW G+L V A+ V AYLFT+ N+ QG+FIFL C+LS++++E+Y + K +
Sbjct: 597 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 654
Score = 60.8 bits (146), Expect = 4e-09
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 41 ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93
AC CN GFS I C+D NEC L++ SCG+ ++C NTEGSY C+C PG+
Sbjct: 44 ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
Query: 94 SNQDRFITNDGTVC 107
S F C
Sbjct: 104 SGAKTFKNESENTC 117
>gi|23397685 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform c [Homo sapiens]
Length = 730
Score = 269 bits (687), Expect = 7e-72
Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)
Query: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390
++S VIS +S+N T +TFT SHR V R + LC FW + + G W++ GC
Sbjct: 351 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 408
Query: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449
+ +T T CRC HL+ FA+LM+ +++ + +LT IT +G+ +SL+CL + TF
Sbjct: 409 TIGTRDTSTICRCTHLSSFAVLMAH---YDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 465
Query: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509
IQ+T T++H L LFLA L+FLV I+ +K+ CSIIAG LHY +LA WM
Sbjct: 466 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 525
Query: 510 IEGIHLYLI-----VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564
+E ++L+L VV F+ K + GY PAV V SAA YGT CWL
Sbjct: 526 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 585
Query: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624
E FIW F+GP C I VNL+ F V ++ + + L EVS N R A A A L
Sbjct: 586 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 645
Query: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
F+LG TW G+L V A+ V AYLFT+ N+ QG+FIFL C+LS++++E+Y + K +
Sbjct: 646 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 703
Score = 60.8 bits (146), Expect = 4e-09
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 41 ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93
AC CN GFS I C+D NEC L++ SCG+ ++C NTEGSY C+C PG+
Sbjct: 44 ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
Query: 94 SNQDRFITNDGTVC 107
S F C
Sbjct: 104 SGAKTFKNESENTC 117
Score = 46.2 bits (108), Expect = 1e-04
Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 8 VVFSTLLNCSYTQNC---TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTI 55
++ + + C C +K C + C G C C+ G F
Sbjct: 57 IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT 116
Query: 56 CEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFR 91
C+D +EC + C + C NT GSY C C PG++
Sbjct: 117 CQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWK 152
>gi|23397683 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform b [Homo sapiens]
Length = 774
Score = 269 bits (687), Expect = 7e-72
Identities = 148/358 (41%), Positives = 207/358 (57%), Gaps = 11/358 (3%)
Query: 331 VISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCE 390
++S VIS +S+N T +TFT SHR V R + LC FW + + G W++ GC
Sbjct: 395 LLSDVISAFLSNND-TQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGC-GHWATTGCS 452
Query: 391 LTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN-ILTRITQLGIIISLICLAICIFTF 449
+ +T T CRC HL+ FA+LM+ +++ + +LT IT +G+ +SL+CL + TF
Sbjct: 453 TIGTRDTSTICRCTHLSSFAVLMAH---YDVQEEDPVLTVITYMGLSVSLLCLLLAALTF 509
Query: 450 WFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMC 509
IQ+T T++H L LFLA L+FLV I+ +K+ CSIIAG LHY +LA WM
Sbjct: 510 LLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWML 569
Query: 510 IEGIHLYLI-----VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWL 564
+E ++L+L VV F+ K + GY PAV V SAA YGT CWL
Sbjct: 570 LEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWL 629
Query: 565 STENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALL 624
E FIW F+GP C I VNL+ F V ++ + + L EVS N R A A A L
Sbjct: 630 QPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQL 689
Query: 625 FLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNV 682
F+LG TW G+L V A+ V AYLFT+ N+ QG+FIFL C+LS++++E+Y + K +
Sbjct: 690 FILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGI 747
Score = 60.8 bits (146), Expect = 4e-09
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 41 ACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTEGSYYCMCVPGFRSS 93
AC CN GFS I C+D NEC L++ SCG+ ++C NTEGSY C+C PG+
Sbjct: 44 ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPV 103
Query: 94 SNQDRFITNDGTVC 107
S F C
Sbjct: 104 SGAKTFKNESENTC 117
Score = 50.1 bits (118), Expect = 7e-06
Identities = 27/107 (25%), Positives = 41/107 (38%), Gaps = 12/107 (11%)
Query: 8 VVFSTLLNCSYTQNC---TKTPCLPNAKCEIRNGIEACYCNMG---------FSGNGVTI 55
++ + + C C +K C + C G C C+ G F
Sbjct: 57 IITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENT 116
Query: 56 CEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITN 102
C+D +EC + C C NT GSY C C+PGF+ + T+
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTD 163
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 16 CSYTQNCTKTP--CLPNAKCEIRNGIEACYCNMGFS--GNGVTICEDDNECGNLTQSCGE 71
C C + P C C G C C GF +C D +EC + C
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDS 176
Query: 72 NANCTNTEGSYYCMCVPGFR 91
+ C NT GSY C C PG++
Sbjct: 177 STVCFNTVGSYSCRCRPGWK 196
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 213 bits (542), Expect = 5e-55
Identities = 127/364 (34%), Positives = 200/364 (54%), Gaps = 27/364 (7%)
Query: 333 SSVISVSMSSNPPTLYE----LEKITFTLSHRKV----------TDRYRSLCAFWNYSPD 378
S +IS+ +S PPTL + IT L HR ++R CAF ++S
Sbjct: 460 SHLISLEVSP-PPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDFSSG 518
Query: 379 TMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNI-LTRITQLGIII 437
G WS+ GC LT N T++ CRC HLT+FAILM P + + + L+ I+ +G +
Sbjct: 519 --EGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSL 576
Query: 438 SLICLAICIFTFWFFSEIQSTRTT---IHKNLCCSLFLAELVFLVGINTNTNKLFCSIIA 494
S++CL + TF S + + R IH NL ++ +A+++ L+ C ++A
Sbjct: 577 SVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMA 636
Query: 495 GLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYR 554
LLHYFFL+AFAWM +EG+HLY +V+ V ++ H+ +Y G+ P ++ S +
Sbjct: 637 VLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMD 696
Query: 555 YYGTTKVCWLSTENNFIWSFIGPACLIILVN---LLAFGVIIYKVFRHTAGLKPEVSCFE 611
YGT+ CWLS + IW+F+ PA +I+VN L+A +I ++ + + S F
Sbjct: 697 SYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQISADNYKIHGDPSAF- 755
Query: 612 NIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKI 671
+ A+ LL +LGT+W+FGVL V +VV Y+F N+ QG+FIFLF C+L+ ++
Sbjct: 756 --KLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEV 813
Query: 672 QEEY 675
+ +
Sbjct: 814 RAAF 817
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 205 bits (521), Expect = 1e-52
Identities = 127/413 (30%), Positives = 206/413 (49%), Gaps = 50/413 (12%)
Query: 284 KRKAAYDSNGNVAVAFVY-YKSIGPLLSSSDNFLLKPQNYDNSEEEERV-------ISSV 335
+R+ D G AVA V Y+++G LL P+ YD R+ V
Sbjct: 2325 RRRRHPDDAGQFAVALVIIYRTLGQLL---------PERYDPDRRSLRLPHRPIINTPMV 2375
Query: 336 ISVSMSSNPPTLYELEK-ITFTLSHRKVTDRYRSLCAFWNYSPDTMN-GSWSSEGCELTY 393
++ S P LE+ + + +V +R + +C FWN+S G WS+ GCEL
Sbjct: 2376 STLVYSEGAPLPRPLERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWSARGCELLS 2435
Query: 394 SNETHTSCRCNHLTHFAILMS-----SGPSIGIKDYNILTRITQLGIIISLICLAICIFT 448
N TH +C+C+H FA+LM +G + +K +T + +SL L +
Sbjct: 2436 RNRTHVACQCSHTASFAVLMDISRRENGEVLPLKI------VTYAAVSLSLAALLVAFVL 2489
Query: 449 FWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWM 508
++S +IHK+L +LFL++LVF++GIN N C+++A LLHY +++ FAW
Sbjct: 2490 LSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMSTFAWT 2549
Query: 509 CIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTEN 568
+E +H+Y ++ V + +Y+ G+ PA+V G + L + YG CWLS ++
Sbjct: 2550 LVESLHVYRMLTEVRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQD 2609
Query: 569 NFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSC--------FENIRSCARGA 620
IWSF GP +I++N + T+ L +VSC + I S R A
Sbjct: 2610 TLIWSFAGPIGAVIIINTV------------TSVLSAKVSCQRKHHYYGKKGIVSLLRTA 2657
Query: 621 LALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQE 673
LL L+ TW+ G+L V ++ YLF + + QG F+ LF CVL++++++
Sbjct: 2658 FLLLLLISATWLLGLLAVNRDALSFHYLFAIFSGLQGPFVLLFHCVLNQEVRK 2710
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
Query: 22 CTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTN-TEG 80
C PC N +C R G C C F+G + C N C C N G
Sbjct: 1367 CYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRCAN--GVCKNGGTCVNLLIG 1424
Query: 81 SYYCMCVPG 89
++C+C PG
Sbjct: 1425 GFHCVCPPG 1433
Score = 39.7 bits (91), Expect = 0.009
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 12/77 (15%)
Query: 16 CSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSG-NGVTICEDDNECGNLTQSCGENAN 74
C CT +PC PN++C +C C+ G+ G N V C N C N+
Sbjct: 1870 CDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACH-LNPCENM-------GA 1921
Query: 75 CTNTEGS---YYCMCVP 88
C + GS Y C C P
Sbjct: 1922 CVRSPGSPQGYVCECGP 1938
Score = 35.0 bits (79), Expect = 0.23
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Query: 37 NGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGF 90
NG+ C C GF+G+ CE + + + CG N C + EG Y C C F
Sbjct: 1345 NGLR-CRCPPGFTGD---YCETEIDLC-YSDPCGANGRCRSREGGYTCECFEDF 1393
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 190 bits (482), Expect = 4e-48
Identities = 119/397 (29%), Positives = 195/397 (49%), Gaps = 33/397 (8%)
Query: 291 SNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVI------SSVISVSMSSNP 344
S G + + Y+++ LL P NYD + RV + V+S+S+ +
Sbjct: 2241 SQGEAVASVIIYRTLAGLL---------PHNYDPDKRSLRVPKRPIINTPVVSISVHDDE 2291
Query: 345 PTLYELEKITFTLSHR--KVTDRYRSLCAFWNYSPDTMN-GSWSSEGCELTYSNETHTSC 401
L T+ R + +R + +C FWN+S G WS+ GCE+ + NE+H SC
Sbjct: 2292 ELLPRALDKPVTVQFRLLETEERTKPICVFWNHSILVSGTGGWSARGCEVVFRNESHVSC 2351
Query: 402 RCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTT 461
+CNH+T FA+LM + ++ + + L + + LA + TF+F + ++ R+
Sbjct: 2352 QCNHMTSFAVLMD----VSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSN 2407
Query: 462 IH---KNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLI 518
H +NL +L LA+LVFL+GIN C++IA LLH+ +L F+W +E +HLY
Sbjct: 2408 QHGIRRNLTAALGLAQLVFLLGINQADLPFACTVIAILLHFLYLCTFSWALLEALHLYRA 2467
Query: 519 VVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPA 578
+ V + +Y+ G+ PA + G + L YG CWLS + IWSF GP
Sbjct: 2468 LTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAGPV 2527
Query: 579 CLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIR--SCARGALALLFLLGTTWIFGVL 636
+ +++ + + A + FE S + + A+L LL TW+ +L
Sbjct: 2528 AFAVSMSVFLY------ILAARASCAAQRQGFEKKGPVSGLQPSFAVLLLLSATWLLALL 2581
Query: 637 HVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQE 673
V +++ YLF N QG FIFL VLS+++++
Sbjct: 2582 SVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRK 2618
Score = 39.7 bits (91), Expect = 0.009
Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 5/70 (7%)
Query: 22 CTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQS-CGENANCTN-TE 79
C PC P+ +C R G C C G++G CE G T C C N
Sbjct: 1292 CYSRPCGPHGRCRSREGGYTCLCRDGYTGEH---CEVSARSGRCTPGVCKNGGTCVNLLV 1348
Query: 80 GSYYCMCVPG 89
G + C C G
Sbjct: 1349 GGFKCDCPSG 1358
Score = 35.0 bits (79), Expect = 0.23
Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 42 CYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGF 90
C C GF+G+ CE + + ++ CG + C + EG Y C+C G+
Sbjct: 1274 CRCPPGFTGD---YCETEVDLC-YSRPCGPHGRCRSREGGYTCLCRDGY 1318
Score = 34.7 bits (78), Expect = 0.30
Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 10/78 (12%)
Query: 16 CSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANC 75
CS C PC N+ C +C C+ G+ G+ T D N C + + C
Sbjct: 1791 CSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEH-------QSVC 1843
Query: 76 TNTEGS---YYCMCVPGF 90
T + Y C C P +
Sbjct: 1844 TRKPSAPHGYTCECPPNY 1861
>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
Length = 3080
Score = 181 bits (458), Expect = 3e-45
Identities = 162/617 (26%), Positives = 274/617 (44%), Gaps = 52/617 (8%)
Query: 105 TVCIENVNANCHLDNVC-IAANINKTLTKIRSIKEPVALLQEVYRN-------SVTDLSP 156
T CI+N + N C I+ N K+ + K+ LLQE+ +++D +
Sbjct: 2412 TRCIKNEDGNA--TRFCSISINTGKSQWEKPKFKQ-CKLLQELPDKIVDLANITISDENA 2468
Query: 157 TDIITYIEILAESSSLLGYKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVN 216
D+ +I L S LG + I S E + + + + VV +K
Sbjct: 2469 EDVAEHILNLINESPALGKEETKIIVSKISDISQCDEISMNLTHVMLQIINVVLEK---- 2524
Query: 217 HRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDI-----ALKVFFFD-SYNMKHIHP 270
+ + +H + LRI + EF ++ AL V D +++
Sbjct: 2525 --QNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSI 2582
Query: 271 HMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSD------NFLLKPQNYDN 324
H +G IF G + + KS+ + S+ NF + +
Sbjct: 2583 HSYEEGTDPEIFLGNVPV----GGILASIYLPKSLTERIPLSNLQTILFNFFGQTSLFKT 2638
Query: 325 SEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSL-CAFWNYSPDTMNGS 383
+ + + V+S S+S + + + TL H Y + CAFW++ + G
Sbjct: 2639 KNVTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGG 2698
Query: 384 WSSEGCELTYSNETHTSCRCNHLTHFAILMS-SGPSIGIKDYNILTRITQLGIIISLICL 442
W+S GC++ +N +T C+C+HLTHF +LM S ++ + IL IT G IS I L
Sbjct: 2699 WNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFL 2758
Query: 443 AICIFTFWFFSEIQST-RTTIHKNLCCSLFLAELVFLVG--INTNTNKLFCSIIAGLLHY 499
+ + T+ F +++ I NLC +L + LVFL+ +++ C A LHY
Sbjct: 2759 GVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHY 2818
Query: 500 FFLAAFAWMCIEGIHLYLIVVGV--IYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYG 557
F L +F WM +E +H+YL +V V IY ++ K F + G+ PA++V + ++ YG
Sbjct: 2819 FLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILK-FCLVGWGIPAIMVAITVSVKKDLYG 2877
Query: 558 ----TTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENI 613
TT CW+ ++ F S + CLI L+NL F ++ ++ ++ + + + + I
Sbjct: 2878 TLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQL--NSVKSQIQKTRRKMI 2935
Query: 614 RSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQE 673
+G ++L FLLG TW F YLF + N QG FIF+F CV+ ++E
Sbjct: 2936 LHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVRE 2995
Query: 674 EYYRLFKNVPCCFGCLR 690
++ + C G LR
Sbjct: 2996 QW-----QIHLCCGWLR 3007
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 171 bits (434), Expect = 2e-42
Identities = 104/359 (28%), Positives = 180/359 (50%), Gaps = 15/359 (4%)
Query: 333 SSVISVSMSSNPPTLYELEKITFTLSHR--KVTDRYRSLCAFWNYSP-DTMNGSWSSEGC 389
S V+SV++ L + + +L R + +R +++C W+ +G W++ C
Sbjct: 2441 SPVVSVAVFHGRNFLRGILESPISLEFRLLQTANRSKAICVQWDPPGLAEQHGVWTARDC 2500
Query: 390 ELTYSNETHTSCRCNHLTHFAILMSSGPSIGIK-DYNILTRITQLGIIISLICLAICIFT 448
EL + N +H CRC+ F +LM + P ++ D +L T + + +S+ L +
Sbjct: 2501 ELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVAALVLTAAI 2560
Query: 449 FWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWM 508
++S IH N+ +L +AEL+FL+GI+ N+L C+ +A LLHYFFL+ FAW+
Sbjct: 2561 LLSLRSLKSNVRGIHANVAAALGVAELLFLLGIHRTHNQLVCTAVAILLHYFFLSTFAWL 2620
Query: 509 CIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTEN 568
++G+HLY + V + ++ G+ PAV++G + L YG CW+S
Sbjct: 2621 FVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHE 2680
Query: 569 NFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLG 628
IWSF GP L+I++N F ++ + T + + + +RS + LL L+
Sbjct: 2681 PLIWSFAGPVVLVIVMNGTMF-LLAARTSCSTGQREAKKTSALTLRS----SFLLLLLVS 2735
Query: 629 TTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFG 687
+W+FG+L V H+ + YL QG+ + L CVL+ + + +P C G
Sbjct: 2736 ASWLFGLLAVNHSILAFHYLHAGLCGLQGLAVLLLFCVLNADARAAW------MPACLG 2788
Score = 39.3 bits (90), Expect = 0.012
Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 5/70 (7%)
Query: 22 CTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQS-CGENANCTNT-E 79
C PC C R G C C F+G CE D E G C CT+
Sbjct: 1439 CYSNPCRNGGACARREGGYTCVCRPRFTGED---CELDTEAGRCVPGVCRNGGTCTDAPN 1495
Query: 80 GSYYCMCVPG 89
G + C C G
Sbjct: 1496 GGFRCQCPAG 1505
Score = 38.5 bits (88), Expect = 0.021
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 10/78 (12%)
Query: 16 CSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANC 75
C T C PC P+A C +C C G+ G G C D L C +C
Sbjct: 1944 CVVTNACASGPCPPHADCRDLWQTFSCTCQPGYYGPG---CVD----ACLLNPCQNQGSC 1996
Query: 76 TNTEGS---YYCMCVPGF 90
+ G+ Y C CV G+
Sbjct: 1997 RHLPGAPHGYTCDCVGGY 2014
Score = 33.5 bits (75), Expect = 0.68
Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 7/73 (9%)
Query: 42 CYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFIT 101
C C GF+G+ CE + + + C C EG Y C+C P F + +D +
Sbjct: 1421 CRCPPGFTGD---FCETELDLC-YSNPCRNGGACARREGGYTCVCRPRF---TGEDCELD 1473
Query: 102 NDGTVCIENVNAN 114
+ C+ V N
Sbjct: 1474 TEAGRCVPGVCRN 1486
>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
Length = 995
Score = 158 bits (400), Expect = 1e-38
Identities = 126/396 (31%), Positives = 188/396 (47%), Gaps = 36/396 (9%)
Query: 314 NFLLKPQNY-DNSEEEERVISSVISVSMSSNPPTLYELEK-ITFTLSHRKVT-DRYRSLC 370
NF P + D S E +IS VIS S+++ T+ L + +T TL H + D C
Sbjct: 491 NFFETPALFQDPSLENLSLISYVISSSVANL--TVRNLTRNVTVTLKHINPSQDELTVRC 548
Query: 371 AFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMS-SGPSIGIKDYNILTR 429
FW+ + G WS GC + T C C+HLT F +L+ S S+ LT
Sbjct: 549 VFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTF 608
Query: 430 ITQLGIIISLICLAICIFTFWFFSEIQSTRTT-IHKNLCCSLFLAELVFLVGINTNTNKL 488
IT +G +S I L++ + T+ F +I+ + I LC +L L LVFL+ K+
Sbjct: 609 ITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKM 668
Query: 489 --FCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVI--YNKGFLHKNFYIFGYLSPAVV 544
C +A LHYF L +F WM +E H+YL +V V Y + ++ K F I G+ PAVV
Sbjct: 669 QGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILK-FCIVGWGVPAVV 727
Query: 545 VGFSAALGYRYYGTTKV-----------CWLSTENNFIWSFIGPACLIILVNLLAFGVII 593
V + YG CW++ F + +G C+I L+N+ F V++
Sbjct: 728 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 787
Query: 594 YKVFR----HTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLF 649
++ R G + + S +++RS A L FLLG TW F +V YLF
Sbjct: 788 VQLCRIKKKKQLGAQRKTS-IQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLF 842
Query: 650 TVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCC 685
+ N QG FIF+F CV +++++ R CC
Sbjct: 843 AIFNTLQGFFIFIFYCVAKENVRKQWRRYL----CC 874
>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
Length = 1003
Score = 158 bits (400), Expect = 1e-38
Identities = 126/396 (31%), Positives = 188/396 (47%), Gaps = 36/396 (9%)
Query: 314 NFLLKPQNY-DNSEEEERVISSVISVSMSSNPPTLYELEK-ITFTLSHRKVT-DRYRSLC 370
NF P + D S E +IS VIS S+++ T+ L + +T TL H + D C
Sbjct: 499 NFFETPALFQDPSLENLSLISYVISSSVANL--TVRNLTRNVTVTLKHINPSQDELTVRC 556
Query: 371 AFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMS-SGPSIGIKDYNILTR 429
FW+ + G WS GC + T C C+HLT F +L+ S S+ LT
Sbjct: 557 VFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTF 616
Query: 430 ITQLGIIISLICLAICIFTFWFFSEIQSTRTT-IHKNLCCSLFLAELVFLVGINTNTNKL 488
IT +G +S I L++ + T+ F +I+ + I LC +L L LVFL+ K+
Sbjct: 617 ITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKM 676
Query: 489 --FCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVI--YNKGFLHKNFYIFGYLSPAVV 544
C +A LHYF L +F WM +E H+YL +V V Y + ++ K F I G+ PAVV
Sbjct: 677 QGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILK-FCIVGWGVPAVV 735
Query: 545 VGFSAALGYRYYGTTKV-----------CWLSTENNFIWSFIGPACLIILVNLLAFGVII 593
V + YG CW++ F + +G C+I L+N+ F V++
Sbjct: 736 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 795
Query: 594 YKVFR----HTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLF 649
++ R G + + S +++RS A L FLLG TW F +V YLF
Sbjct: 796 VQLCRIKKKKQLGAQRKTS-IQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLF 850
Query: 650 TVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCC 685
+ N QG FIF+F CV +++++ R CC
Sbjct: 851 AIFNTLQGFFIFIFYCVAKENVRKQWRRYL----CC 882
>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
Length = 1017
Score = 158 bits (400), Expect = 1e-38
Identities = 126/396 (31%), Positives = 188/396 (47%), Gaps = 36/396 (9%)
Query: 314 NFLLKPQNY-DNSEEEERVISSVISVSMSSNPPTLYELEK-ITFTLSHRKVT-DRYRSLC 370
NF P + D S E +IS VIS S+++ T+ L + +T TL H + D C
Sbjct: 513 NFFETPALFQDPSLENLSLISYVISSSVANL--TVRNLTRNVTVTLKHINPSQDELTVRC 570
Query: 371 AFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMS-SGPSIGIKDYNILTR 429
FW+ + G WS GC + T C C+HLT F +L+ S S+ LT
Sbjct: 571 VFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTF 630
Query: 430 ITQLGIIISLICLAICIFTFWFFSEIQSTRTT-IHKNLCCSLFLAELVFLVGINTNTNKL 488
IT +G +S I L++ + T+ F +I+ + I LC +L L LVFL+ K+
Sbjct: 631 ITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKM 690
Query: 489 --FCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVI--YNKGFLHKNFYIFGYLSPAVV 544
C +A LHYF L +F WM +E H+YL +V V Y + ++ K F I G+ PAVV
Sbjct: 691 QGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILK-FCIVGWGVPAVV 749
Query: 545 VGFSAALGYRYYGTTKV-----------CWLSTENNFIWSFIGPACLIILVNLLAFGVII 593
V + YG CW++ F + +G C+I L+N+ F V++
Sbjct: 750 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 809
Query: 594 YKVFR----HTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLF 649
++ R G + + S +++RS A L FLLG TW F +V YLF
Sbjct: 810 VQLCRIKKKKQLGAQRKTS-IQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLF 864
Query: 650 TVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCC 685
+ N QG FIF+F CV +++++ R CC
Sbjct: 865 AIFNTLQGFFIFIFYCVAKENVRKQWRRYL----CC 896
>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
Length = 1014
Score = 158 bits (400), Expect = 1e-38
Identities = 126/396 (31%), Positives = 188/396 (47%), Gaps = 36/396 (9%)
Query: 314 NFLLKPQNY-DNSEEEERVISSVISVSMSSNPPTLYELEK-ITFTLSHRKVT-DRYRSLC 370
NF P + D S E +IS VIS S+++ T+ L + +T TL H + D C
Sbjct: 510 NFFETPALFQDPSLENLSLISYVISSSVANL--TVRNLTRNVTVTLKHINPSQDELTVRC 567
Query: 371 AFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMS-SGPSIGIKDYNILTR 429
FW+ + G WS GC + T C C+HLT F +L+ S S+ LT
Sbjct: 568 VFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTF 627
Query: 430 ITQLGIIISLICLAICIFTFWFFSEIQSTRTT-IHKNLCCSLFLAELVFLVGINTNTNKL 488
IT +G +S I L++ + T+ F +I+ + I LC +L L LVFL+ K+
Sbjct: 628 ITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKM 687
Query: 489 --FCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVI--YNKGFLHKNFYIFGYLSPAVV 544
C +A LHYF L +F WM +E H+YL +V V Y + ++ K F I G+ PAVV
Sbjct: 688 QGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILK-FCIVGWGVPAVV 746
Query: 545 VGFSAALGYRYYGTTKV-----------CWLSTENNFIWSFIGPACLIILVNLLAFGVII 593
V + YG CW++ F + +G C+I L+N+ F V++
Sbjct: 747 VTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 806
Query: 594 YKVFR----HTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLF 649
++ R G + + S +++RS A L FLLG TW F +V YLF
Sbjct: 807 VQLCRIKKKKQLGAQRKTS-IQDLRSIA----GLTFLLGITWGFAFFAWGPVNVTFMYLF 861
Query: 650 TVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCC 685
+ N QG FIF+F CV +++++ R CC
Sbjct: 862 AIFNTLQGFFIFIFYCVAKENVRKQWRRYL----CC 893
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 158 bits (400), Expect = 1e-38
Identities = 122/387 (31%), Positives = 186/387 (48%), Gaps = 56/387 (14%)
Query: 331 VISSVISVSMSSNPPTLYELEK-ITFTLSH--RKVTDRYRSLCAFWNYS-PDTMNGSWSS 386
V S V++V++ PPT E IT LS+ TD + CA W+YS D +G W +
Sbjct: 837 VTSRVMTVTV--RPPTQPPAEPLITVELSYIINGTTDPH---CASWDYSRADASSGDWDT 891
Query: 387 EGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIIS---LICLA 443
E C+ + HT C+C HL+ FA+L + ++ + +G +S L+ L
Sbjct: 892 ENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLL 951
Query: 444 ICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLA 503
FW F I+S R+ I N C S+ + ++ LVG + +K C++ A LH+FFL+
Sbjct: 952 AIYAAFWRF--IKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLS 1009
Query: 504 AFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVV----VGFSAALGYRYYGTT 559
+F W+ E YL V+G + + + K F G+ PA+V VGF+ G YGT+
Sbjct: 1010 SFCWVLTEAWQSYLAVIGRMRTR-LVRKRFLCLGWGLPALVVAVSVGFTRTKG---YGTS 1065
Query: 560 KVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLK-------------PE 606
CWLS E +++F+GPA +I+LVN+L G+I++ G+ P
Sbjct: 1066 SYCWLSLEGGLLYAFVGPAAVIVLVNML-IGIIVFNKLMARDGISDKSKKQRAGSERCPW 1124
Query: 607 VSCFENIRSC------------ARGALALLF-------LLGTTWIFGVLHVV-HASVVTA 646
S +C AR A+A L+ LL TW+ VL + SV+
Sbjct: 1125 ASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQ 1184
Query: 647 YLFTVSNAFQGMFIFLFLCVLSRKIQE 673
LF V N+ QG I C L R++Q+
Sbjct: 1185 ALFAVFNSAQGFVITAVHCFLRREVQD 1211
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
sapiens]
Length = 1584
Score = 158 bits (399), Expect = 2e-38
Identities = 138/549 (25%), Positives = 239/549 (43%), Gaps = 66/549 (12%)
Query: 143 LQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISAKDTLSNSTLTEFVKTVNNFV 202
+ E++R + +P D+ +++IL S+LL +N + L+ E + V +FV
Sbjct: 693 MTEIFRRAYYSPTPGDVQNFVQIL---SNLLAEENRDKWEEAQLAGPNAKELFRLVEDFV 749
Query: 203 QRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDS 262
F + D + Q T + S K + +TDI+ F
Sbjct: 750 DVIGFRMKD--------------LRDAYQVTDNLVLSIHKLPA--SGATDIS-----FPM 788
Query: 263 YNMKHIHPHMNMDGDYI----NIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLK 318
+ + D + ++F D V V Y+++G L+ N +
Sbjct: 789 KGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFVVGTVLYRNLGSFLALQRNTTV- 847
Query: 319 PQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNY--- 375
+ S VISV++ P +L +I F + T++ C W+
Sbjct: 848 ------------LNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQ---TCILWDETDV 892
Query: 376 ---SPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNI--LTRI 430
S G WS GC + T C C+ L+ FAIL ++ + +T I
Sbjct: 893 PSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLI 952
Query: 431 TQLGII-ISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLF 489
G+ ++L+ L I + W + I+S R+ I N C S+ + + L+G NK+
Sbjct: 953 VGCGVSSLTLLMLVIIYVSVWRY--IRSERSVILINFCLSIISSNALILIGQTQTRNKVV 1010
Query: 490 CSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVV----V 545
C+++A LH+FFL++F W+ E Y+ V G + N+ + K F G+ PA+V V
Sbjct: 1011 CTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGHLRNR-LIRKRFLCLGWGLPALVVAISV 1069
Query: 546 GFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKP 605
GF+ A G Y T CWLS E +++F+GPA ++LVN++ G++++ G+
Sbjct: 1070 GFTKAKG---YSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMV-IGILVFNKLVSKDGI-T 1124
Query: 606 EVSCFENIRSCARGALALLFLLGTTWIFGVLHVV-HASVVTAYLFTVSNAFQGMFIFLFL 664
+ E + + +L LL TW+ VL V S + LF V ++ +G I +
Sbjct: 1125 DKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVH 1184
Query: 665 CVLSRKIQE 673
C+L R++Q+
Sbjct: 1185 CILRREVQD 1193
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 156 bits (394), Expect = 7e-38
Identities = 121/440 (27%), Positives = 199/440 (45%), Gaps = 64/440 (14%)
Query: 283 PKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSS 342
P D + + V YK++ +L + N+ + + S +I V++
Sbjct: 748 PVSSKELDESSVFVLGAVLYKNLDLILPTLRNYTV-------------INSKIIVVTIRP 794
Query: 343 NPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMN-GSWSSEGCELTYSNETHTSC 401
P T +I + Y C W+ S + G+WS++GC+ ++ +HT C
Sbjct: 795 EPKTTDSFLEIELAHLANGTLNPY---CVLWDDSKTNESLGTWSTQGCKTVLTDASHTKC 851
Query: 402 RCNHLTHFAILMSSGPSIGIKDYNI--LTRITQLGI-IISLICLAICIFTFWFFSEIQST 458
C+ L+ FAIL I ++ +T I G+ ++LI LA+ W + I+S
Sbjct: 852 LCDRLSTFAILAQQPREIIMESSGTPSVTLIVGSGLSCLALITLAVVYAALWRY--IRSE 909
Query: 459 RTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLI 518
R+ I N C S+ + ++ LVG NK C+ LH+FFLA+F W+ E Y+
Sbjct: 910 RSIILINFCLSIISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVLTEAWQSYMA 969
Query: 519 VVGVIYNKGFLHKNFYIFGYLSPAVV----VGFSAALGYRYYGTTKVCWLSTENNFIWSF 574
V G I + + K F G+ PA+V VGF+ G YGT CWLS E +++F
Sbjct: 970 VTGKIRTR-LIRKRFLCLGWGLPALVVATSVGFTRTKG---YGTDHYCWLSLEGGLLYAF 1025
Query: 575 IGPACLIILVNLLAFGVIIY-----------KVFRHTAGLKPE--------------VSC 609
+GPA ++LVN++ G++++ K +H AG E VS
Sbjct: 1026 VGPAAAVVLVNMV-IGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCGVVST 1084
Query: 610 FENIRSCARGALALLF-------LLGTTWIFGVLHVV-HASVVTAYLFTVSNAFQGMFIF 661
+ A A+A L+ LL TW+ VL + S++ LF V ++ QG I
Sbjct: 1085 TALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQGFVIV 1144
Query: 662 LFLCVLSRKIQEEYYRLFKN 681
+ C+L R++Q+ + +N
Sbjct: 1145 MVHCILRREVQDAFRCRLRN 1164
>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
sapiens]
Length = 1221
Score = 153 bits (387), Expect = 4e-37
Identities = 109/375 (29%), Positives = 187/375 (49%), Gaps = 24/375 (6%)
Query: 323 DNSEEEERVISSVISVSMSSNPPTLYEL-EKITFTLSHRKVTDRYRSLCAFWNYSPDTMN 381
D + + ++S V++ S+ + T+ L + + + H + + + +CAFW+ + +
Sbjct: 757 DVGPQRKTLVSYVMACSIGNI--TIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSF 814
Query: 382 GSWSSEGCELTY-SNETHTSCRCNHLTHFAILMS---SGPSIGIKDYNILTRITQLGIII 437
G W++ GC S+ + T C CNH THF +LM S + ++ +LT I+ +G I
Sbjct: 815 GGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIGCGI 874
Query: 438 SLICLAICIFTFWFFSEIQSTRTT-IHKNLCCSLFLAELVFLV-GINTNTN-KLFCSIIA 494
S I A + T+ F +++ + I NL +L L+FL+ G T+ N C +A
Sbjct: 875 SAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVA 934
Query: 495 GLLHYFFLAAFAWMCIEGIHLYLIVVGVI--YNKGFLHKNFYIFGYLSPAVVVGFSAA-- 550
LLH+F LA F WM +E IH+Y+ +V V Y + ++ K F I G+ PA+VV A
Sbjct: 935 VLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILK-FCIIGWGLPALVVSVVLASR 993
Query: 551 -----LGYRYYGTTK---VCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAG 602
G YG K CW+ F + G ++ +N+ F V++ ++ G
Sbjct: 994 NNNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRN-G 1052
Query: 603 LKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFL 662
+ + E + R ++L FLLG TW F ++ YLF++ N+ QG+FIF+
Sbjct: 1053 KRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFI 1112
Query: 663 FLCVLSRKIQEEYYR 677
F C + +Q+++ R
Sbjct: 1113 FHCAMKENVQKQWRR 1127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,068,410
Number of Sequences: 37866
Number of extensions: 1089224
Number of successful extensions: 5300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 3591
Number of HSP's gapped (non-prelim): 1129
length of query: 690
length of database: 18,247,518
effective HSP length: 109
effective length of query: 581
effective length of database: 14,120,124
effective search space: 8203792044
effective search space used: 8203792044
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.