Guide to the Human Genome
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Search of human proteins with 148746209

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148746209 testis enhanced gene transcript (BAX inhibitor 1)
isoform 1 [Homo sapiens]
         (237 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148746181 testis enhanced gene transcript (BAX inhibitor 1) i...   473   e-134
gi|148746209 testis enhanced gene transcript (BAX inhibitor 1) i...   473   e-134
gi|116812579 transmembrane BAX inhibitor motif containing 4 [Hom...    65   5e-11
gi|118200356 growth hormone inducible transmembrane protein [Hom...    53   3e-07
gi|50593008 transmembrane BAX inhibitor motif containing 1 [Homo...    38   0.007
gi|34101290 Fas apoptotic inhibitory molecule 2 [Homo sapiens]         36   0.033
gi|109638743 hypothetical protein LOC83723 [Homo sapiens]              28   5.3  
gi|21314654 ring finger protein 139 [Homo sapiens]                     28   9.0  
gi|216547942 solute carrier family 35, member B3 [Homo sapiens]        28   9.0  
gi|216547920 solute carrier family 35, member B3 [Homo sapiens]        28   9.0  
gi|21361503 solute carrier family 35, member B3 [Homo sapiens]         28   9.0  

>gi|148746181 testis enhanced gene transcript (BAX inhibitor 1)
           isoform 2 [Homo sapiens]
          Length = 295

 Score =  473 bits (1218), Expect = e-134
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS 60
           MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS
Sbjct: 59  MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS 118

Query: 61  ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG 120
           ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG
Sbjct: 119 ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG 178

Query: 121 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV 180
           TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV
Sbjct: 179 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV 238

Query: 181 MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK 237
           MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK
Sbjct: 239 MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK 295


>gi|148746209 testis enhanced gene transcript (BAX inhibitor 1)
           isoform 1 [Homo sapiens]
          Length = 237

 Score =  473 bits (1218), Expect = e-134
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS 60
           MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS
Sbjct: 1   MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS 60

Query: 61  ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG 120
           ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG
Sbjct: 61  ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG 120

Query: 121 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV 180
           TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV
Sbjct: 121 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV 180

Query: 181 MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK 237
           MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK
Sbjct: 181 MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK 237


>gi|116812579 transmembrane BAX inhibitor motif containing 4 [Homo
           sapiens]
          Length = 238

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 61/213 (28%), Positives = 100/213 (46%), Gaps = 18/213 (8%)

Query: 27  LKKVYASFALCMFVAAAGA----YVHMVTHFIQAG----LLSALGSLILMIWLMATPHSH 78
           L+KVY+  +L + +    +    Y   V  F+       LL ALGSL L+  L+   H +
Sbjct: 35  LRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLGLIFALILNRHKY 94

Query: 79  ETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMGTAMIFTCFTLSALYARRR 138
                 L LL GF  L  + +   + F    +  I+  AF+ T  +F   T+  L +++ 
Sbjct: 95  PLN---LYLLFGFTLLEALTVAVVVTF---YDVYIILQAFILTTTVFFGLTVYTLQSKKD 148

Query: 139 SYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEH 198
              F  G L + L +L LS     FF S  +       G ++ CGF+++DT  ++ K   
Sbjct: 149 FSKFGAG-LFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLMHKL-- 205

Query: 199 GDQDYIWHCIDLFLDFITVFRKLMMIL-AMNEK 230
             ++Y+   I L+LD I +F  L+  L A+N+K
Sbjct: 206 SPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK 238


>gi|118200356 growth hormone inducible transmembrane protein [Homo
           sapiens]
          Length = 345

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 38/124 (30%), Positives = 64/124 (51%), Gaps = 11/124 (8%)

Query: 121 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFF-----GSIWLFQANLY 175
           TA I    +  A+ A    +L +G  L   L L+ +SSLG++F          L+   +Y
Sbjct: 222 TAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSSLGSMFLPPTTVAGATLYSVAMY 281

Query: 176 VGLVVMCGFVLFDTQLIIEKAE----HGDQDY--IWHCIDLFLDFITVFRKLMMILAMNE 229
            GLV+   F+L+DTQ +I++AE    +G Q Y  I   + +++D + +F ++  +LA   
Sbjct: 282 GGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYMDTLNIFMRVATMLATGG 341

Query: 230 KDKK 233
             KK
Sbjct: 342 NRKK 345


>gi|50593008 transmembrane BAX inhibitor motif containing 1 [Homo
           sapiens]
          Length = 311

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 6/143 (4%)

Query: 87  LLAGFAFLTGVGLGP--ALEFCIAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLG 144
           LL  F F  G   G   ++    AV  +++ TA +  ++   CF     +        + 
Sbjct: 167 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 226

Query: 145 GILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEH--GDQD 202
           GI++    ++  +S+   F    WL      +G +    F+ +DTQL++   +H    +D
Sbjct: 227 GIVLLVTGIV--TSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPED 284

Query: 203 YIWHCIDLFLDFITVFRKLMMIL 225
           YI   + ++ D I +F  ++ ++
Sbjct: 285 YITGALQIYTDIIYIFTFVLQLM 307


>gi|34101290 Fas apoptotic inhibitory molecule 2 [Homo sapiens]
          Length = 316

 Score = 35.8 bits (81), Expect = 0.033
 Identities = 27/130 (20%), Positives = 52/130 (40%), Gaps = 15/130 (11%)

Query: 116 TAFMGTAMIFTCFTLSAL---------YARRRSYLFLGGILMSALSLLLLSSLGNVFFGS 166
           +++  T  +  C  ++AL         +  +  +    G+L   L  L  S L       
Sbjct: 187 SSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLP 246

Query: 167 I----WLFQANLYVGLVVMCGFVLFDTQLIIEKAEHG--DQDYIWHCIDLFLDFITVFRK 220
                WL      +G  V   F+  DTQL++    H    ++YI+  ++++LD I +F  
Sbjct: 247 FQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTF 306

Query: 221 LMMILAMNEK 230
            + +   N +
Sbjct: 307 FLQLFGTNRE 316


>gi|109638743 hypothetical protein LOC83723 [Homo sapiens]
          Length = 274

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 12/31 (38%), Positives = 20/31 (64%)

Query: 122 AMIFTCFTLSALYARRRSYLFLGGILMSALS 152
           AM+  CF LS ++ + +   FLG +LM+ +S
Sbjct: 138 AMVLVCFPLSVVWRQGKGDFFLGCMLMAEVS 168


>gi|21314654 ring finger protein 139 [Homo sapiens]
          Length = 664

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 30/190 (15%)

Query: 40  VAAAGAYVHMVTHFIQAGLLSALGSLILMIWLMATPHSHETEQKRLGLLAGFAFL----- 94
           V    A +  V H++  G+L+ +GS              E + +RLG +A   F      
Sbjct: 291 VLGMSAVISSVAHYLGLGILAFIGST-------------EEDDRRLGFVAPVLFFILALQ 337

Query: 95  TGV-GLGPALEFC-IAVNPSILPTAFMG-----TAMIFTCFTLSALYARRRSY--LFLGG 145
           TG+ GL P      ++ N  +L TA +      T  +    + S + + RR +  LF+  
Sbjct: 338 TGLSGLRPEERLIRLSRNMCLLLTAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSA 397

Query: 146 ILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIW 205
            L   L +LL   L + +  + WLF    +   V +C  V+    +       G  + +W
Sbjct: 398 CLF-ILPVLLSYVLWHHYALNTWLFAVTAF--CVELCLKVIVSLTVYTLFMIDGYYNVLW 454

Query: 206 HCIDLFLDFI 215
             +D ++ ++
Sbjct: 455 EKLDDYVYYV 464


>gi|216547942 solute carrier family 35, member B3 [Homo sapiens]
          Length = 401

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)

Query: 98  GLGPALEFCIAVNPSILPTAFMGTAMIFTC---FTLSALYARRRSYLFLGGILMSALSLL 154
           GLGPA+ FC A N    P    G A +F+    F +S + A  + +  L  + ++     
Sbjct: 281 GLGPAVTFC-AKN----PVRTYGYAFLFSLTGYFGISFVLALIKIFGALIAVTVTTGRKA 335

Query: 155 LLSSLGNVFFGSIWLFQANLYVGLVVMCGFVL 186
           +   L  +FF   + FQ  ++ GL+V+ G  L
Sbjct: 336 MTIVLSFIFFAKPFTFQ-YVWSGLLVVLGIFL 366


>gi|216547920 solute carrier family 35, member B3 [Homo sapiens]
          Length = 401

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)

Query: 98  GLGPALEFCIAVNPSILPTAFMGTAMIFTC---FTLSALYARRRSYLFLGGILMSALSLL 154
           GLGPA+ FC A N    P    G A +F+    F +S + A  + +  L  + ++     
Sbjct: 281 GLGPAVTFC-AKN----PVRTYGYAFLFSLTGYFGISFVLALIKIFGALIAVTVTTGRKA 335

Query: 155 LLSSLGNVFFGSIWLFQANLYVGLVVMCGFVL 186
           +   L  +FF   + FQ  ++ GL+V+ G  L
Sbjct: 336 MTIVLSFIFFAKPFTFQ-YVWSGLLVVLGIFL 366


>gi|21361503 solute carrier family 35, member B3 [Homo sapiens]
          Length = 401

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)

Query: 98  GLGPALEFCIAVNPSILPTAFMGTAMIFTC---FTLSALYARRRSYLFLGGILMSALSLL 154
           GLGPA+ FC A N    P    G A +F+    F +S + A  + +  L  + ++     
Sbjct: 281 GLGPAVTFC-AKN----PVRTYGYAFLFSLTGYFGISFVLALIKIFGALIAVTVTTGRKA 335

Query: 155 LLSSLGNVFFGSIWLFQANLYVGLVVMCGFVL 186
           +   L  +FF   + FQ  ++ GL+V+ G  L
Sbjct: 336 MTIVLSFIFFAKPFTFQ-YVWSGLLVVLGIFL 366


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.143    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,709,617
Number of Sequences: 37866
Number of extensions: 292547
Number of successful extensions: 821
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 813
Number of HSP's gapped (non-prelim): 12
length of query: 237
length of database: 18,247,518
effective HSP length: 99
effective length of query: 138
effective length of database: 14,498,784
effective search space: 2000832192
effective search space used: 2000832192
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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