BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo sapiens] (477 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 960 0.0 gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 864 0.0 gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 609 e-174 gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 609 e-174 gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 600 e-172 gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 585 e-167 gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 585 e-167 gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 584 e-167 gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 514 e-146 gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 320 2e-87 gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 182 4e-46 gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 181 1e-45 gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 137 2e-32 gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 132 7e-31 gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 131 2e-30 gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 131 2e-30 gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 127 2e-29 gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 119 8e-27 gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 109 5e-24 gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 109 5e-24 gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 109 5e-24 gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 108 1e-23 gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 104 2e-22 gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 104 2e-22 gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 104 2e-22 gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 102 8e-22 gi|46094065 mitochondrial carrier family protein [Homo sapiens] 100 3e-21 gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 98 1e-20 gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 97 2e-20 gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 97 2e-20 >gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo sapiens] Length = 477 Score = 960 bits (2481), Expect = 0.0 Identities = 477/477 (100%), Positives = 477/477 (100%) Query: 1 MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE 60 MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE Sbjct: 1 MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE 60 Query: 61 EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 120 EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL Sbjct: 61 EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 120 Query: 121 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 180 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI Sbjct: 121 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 180 Query: 181 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 240 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ Sbjct: 181 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 240 Query: 241 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 300 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA Sbjct: 241 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 300 Query: 301 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 360 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI Sbjct: 301 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 360 Query: 361 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 420 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE Sbjct: 361 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 420 Query: 421 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK Sbjct: 421 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 >gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo sapiens] Length = 458 Score = 864 bits (2233), Expect = 0.0 Identities = 433/454 (95%), Positives = 438/454 (96%) Query: 24 YETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKY 83 Y LF LD N DG +DI ELQEGL ++G + +KIFTTGDVNKDGKLDFEEFMKY Sbjct: 5 YGDLFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEEFMKY 64 Query: 84 LKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVD 143 LKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVD Sbjct: 65 LKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVD 124 Query: 144 WNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGI 203 WNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGI Sbjct: 125 WNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGI 184 Query: 204 AGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAP 263 AGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAP Sbjct: 185 AGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAP 244 Query: 264 ETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ 323 ETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ Sbjct: 245 ETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ 304 Query: 324 YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNP 383 YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNP Sbjct: 305 YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNP 364 Query: 384 GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGL 443 GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGL Sbjct: 365 GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGL 424 Query: 444 YRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 YRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK Sbjct: 425 YRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458 >gi|239755174 PREDICTED: similar to solute carrier family 25, member 25 isoform 1 [Homo sapiens] Length = 503 Score = 609 bits (1570), Expect = e-174 Identities = 293/465 (63%), Positives = 369/465 (79%) Query: 13 AACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKD 72 A C + R LFQ LD N DG + + +L GLR LG+ + +KI GD + D Sbjct: 39 AICGGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLD 98 Query: 73 GKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQ 132 G+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+ ISEQQAE IL+ Sbjct: 99 GQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILK 158 Query: 133 SIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSG 192 S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+PDEFT +E+++G Sbjct: 159 SMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTG 218 Query: 193 QWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWR 252 WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF QM++EGG RSLWR Sbjct: 219 MWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWR 278 Query: 253 GNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVM 312 GNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA AQ+ IYPMEV+ Sbjct: 279 GNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVL 338 Query: 313 KTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW 372 KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGIDLAVYE LK+ W Sbjct: 339 KTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAW 398 Query: 373 LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFR 432 L ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +EG+P++ M LF+ Sbjct: 399 LQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK 458 Query: 433 RIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV + Sbjct: 459 HILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503 >gi|56699403 solute carrier family 25, member 25 isoform b [Homo sapiens] Length = 503 Score = 609 bits (1570), Expect = e-174 Identities = 293/465 (63%), Positives = 369/465 (79%) Query: 13 AACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKD 72 A C + R LFQ LD N DG + + +L GLR LG+ + +KI GD + D Sbjct: 39 AICGGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLD 98 Query: 73 GKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQ 132 G+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+ ISEQQAE IL+ Sbjct: 99 GQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILK 158 Query: 133 SIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSG 192 S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+PDEFT +E+++G Sbjct: 159 SMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTG 218 Query: 193 QWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWR 252 WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF QM++EGG RSLWR Sbjct: 219 MWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWR 278 Query: 253 GNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVM 312 GNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA AQ+ IYPMEV+ Sbjct: 279 GNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVL 338 Query: 313 KTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW 372 KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGIDLAVYE LK+ W Sbjct: 339 KTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAW 398 Query: 373 LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFR 432 L ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +EG+P++ M LF+ Sbjct: 399 LQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK 458 Query: 433 RIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV + Sbjct: 459 HILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503 >gi|48476342 solute carrier family 25, member 23 [Homo sapiens] Length = 468 Score = 600 bits (1547), Expect = e-172 Identities = 285/462 (61%), Positives = 369/462 (79%), Gaps = 1/462 (0%) Query: 17 DAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQD-AEEKIFTTGDVNKDGKL 75 DAE+ R+ LF+ LD N DG VD+ EL++GL LG A++ I + GD + DG L Sbjct: 7 DAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGGL 66 Query: 76 DFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSID 135 D EEF +YL++ E+++ L F SLD+N DG I+ SEI QS + LG++IS +QAE IL S+D Sbjct: 67 DLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSMD 126 Query: 136 VDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWW 195 DGTMT+DW EWRD+FL + + ++E+++ FWKHST +DIG+ LT+PDEF++ EK +G WW Sbjct: 127 RDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWW 186 Query: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 255 +QL+AG +AGAVSRT TAPLDRLK+ MQVH SK++++NI GG R MV EGGIRSLWRGNG Sbjct: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNG 246 Query: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 315 NV+KIAPE+A+KF AYEQ K+ + + + + ERF++GS+AGATAQT IYPMEV+KTR Sbjct: 247 INVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTR 306 Query: 316 LAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDN 375 L + +TGQY G+ DCA++IL+ EG AFY+GY+PN+LGIIPYAGIDLAVYE LK++WL Sbjct: 307 LTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQ 366 Query: 376 FAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRII 435 ++ DS +PG++VLL CG +SSTCGQ+ASYPLALVRTRMQAQA +EG PQL+M+GL R I+ Sbjct: 367 YSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHIL 426 Query: 436 SKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 S+EG+ GLYRGI PNFMKV+PAV ISYVVYENMKQ LGVT + Sbjct: 427 SQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468 >gi|239755176 PREDICTED: similar to solute carrier family 25, member 25 isoform 2 [Homo sapiens] Length = 469 Score = 585 bits (1507), Expect = e-167 Identities = 276/418 (66%), Positives = 347/418 (83%) Query: 60 EEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLG 119 ++KI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG Sbjct: 52 KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111 Query: 120 LTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLT 179 + ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT Sbjct: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171 Query: 180 IPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR 239 +PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Sbjct: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231 Query: 240 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 299 QM++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AG Sbjct: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291 Query: 300 ATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359 A AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAG Sbjct: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351 Query: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419 IDLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA + Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411 Query: 420 EGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 EG+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV + Sbjct: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469 >gi|56699401 solute carrier family 25, member 25 isoform a [Homo sapiens] Length = 469 Score = 585 bits (1507), Expect = e-167 Identities = 276/418 (66%), Positives = 347/418 (83%) Query: 60 EEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLG 119 ++KI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG Sbjct: 52 KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111 Query: 120 LTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLT 179 + ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT Sbjct: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171 Query: 180 IPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR 239 +PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Sbjct: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231 Query: 240 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 299 QM++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AG Sbjct: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291 Query: 300 ATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359 A AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAG Sbjct: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351 Query: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419 IDLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA + Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411 Query: 420 EGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 EG+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV + Sbjct: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469 >gi|56699407 solute carrier family 25, member 25 isoform c [Homo sapiens] Length = 489 Score = 584 bits (1505), Expect = e-167 Identities = 276/417 (66%), Positives = 346/417 (82%) Query: 61 EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 120 +KI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+ Sbjct: 73 KKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 132 Query: 121 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 180 ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+ Sbjct: 133 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 192 Query: 181 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 240 PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Q Sbjct: 193 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 252 Query: 241 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 300 M++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA Sbjct: 253 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 312 Query: 301 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 360 AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGI Sbjct: 313 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 372 Query: 361 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 420 DLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +E Sbjct: 373 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 432 Query: 421 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477 G+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV + Sbjct: 433 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 489 >gi|56699405 solute carrier family 25, member 25 isoform d [Homo sapiens] Length = 366 Score = 514 bits (1325), Expect = e-146 Identities = 243/366 (66%), Positives = 304/366 (83%) Query: 112 VQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTG 171 +QSL+ LG+ ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST Sbjct: 1 MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 60 Query: 172 IDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDK 231 D+G++LT+PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ Sbjct: 61 FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 120 Query: 232 MNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFER 291 M I GGF QM++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER Sbjct: 121 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 180 Query: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 351 ++GS+AGA AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+ Sbjct: 181 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 240 Query: 352 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRT 411 LGIIPYAGIDLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRT Sbjct: 241 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 300 Query: 412 RMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQT 471 RMQAQA +EG+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K T Sbjct: 301 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 360 Query: 472 LGVTQK 477 LGV + Sbjct: 361 LGVQSR 366 >gi|149274607 solute carrier family 25, member 41 [Homo sapiens] Length = 370 Score = 320 bits (819), Expect = 2e-87 Identities = 166/303 (54%), Positives = 218/303 (71%), Gaps = 3/303 (0%) Query: 172 IDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDK 231 +D G+ L +P E E + K W + LL+G +AGAVSRT TAPLDR K+ MQV+ SK++ Sbjct: 71 LDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNF 129 Query: 232 MNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFER 291 N+ GG + MV+EGG RSLWRGNG NV+KIAPE A+KF +EQ K ER Sbjct: 130 TNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQER 189 Query: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 351 ++GS+A A +QT I PMEV+KTRL + +TGQY G+ DCA++IL+ EG A Y+GY+PN+ Sbjct: 190 LLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNM 249 Query: 352 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRT 411 LGIIPYA DLAVYE+L+ +W+ + +D +P +V L LS+TCGQ+ASYPL LVRT Sbjct: 250 LGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRT 308 Query: 412 RMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQT 471 RMQAQ +EGS M G+ +RI++++G GLYRG+TP +KVLPA GISYVVYE MK+T Sbjct: 309 RMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKT 367 Query: 472 LGV 474 LG+ Sbjct: 368 LGI 370 >gi|27544933 solute carrier family 25, member 16 [Homo sapiens] Length = 332 Score = 182 bits (463), Expect = 4e-46 Identities = 107/292 (36%), Positives = 161/292 (55%), Gaps = 15/292 (5%) Query: 194 WWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 253 W R LAGGIAG ++T+ APLDR+K+++Q H + +F R + ++ G L++G Sbjct: 36 WLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKG 95 Query: 254 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMK 313 NG +I+I P A++F A+E YK L+T + G R ++GSMAG TA YP+++++ Sbjct: 96 NGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVR 155 Query: 314 TRLAVGKTGQ--YSGIYDCAKKI-LKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKS 370 RLA G+ Y+GI K I K G FY+G +P +LG+ PYAG+ + LKS Sbjct: 156 VRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKS 215 Query: 371 YWLDNF-----AKDSVNPGVMVL-----LGCGALSSTCGQLASYPLALVRTRMQAQAML- 419 L + S NP V+VL L CG ++ Q SYP + R RMQ +L Sbjct: 216 VGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLP 275 Query: 420 EGSPQLNMVGLFRRIISKEGI-PGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 E L M + + GI GLYRG++ N+++ +P+ +++ YE MKQ Sbjct: 276 EFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327 Score = 68.6 bits (166), Expect = 1e-11 Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 23/198 (11%) Query: 197 QLLAGGIAGAVSRTSTAPLD--RLKIMMQVHGSKSDKMNIFGGFRQM-VKEGGIRSLWRG 253 +L+AG +AG + T PLD R+++ QV G S I F+ + KEGG +RG Sbjct: 133 RLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHS-YTGIIHAFKTIYAKEGGFFGFYRG 191 Query: 254 NGTNVIKIAPETAVKFWAYEQYKKL-LTEEGQKIG-------------TFERFISGSMAG 299 ++ +AP V F+ + K + L+ +G T + G +AG Sbjct: 192 LMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAG 251 Query: 300 ATAQTFIYPMEVMKTRLAVGKT----GQYSGIYDCAKKILKHEGLG-AFYKGYVPNLLGI 354 A AQT YP +V + R+ +G + + D K + H G+ Y+G N + Sbjct: 252 AIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRC 311 Query: 355 IPYAGIDLAVYELLKSYW 372 IP + YEL+K ++ Sbjct: 312 IPSQAVAFTTYELMKQFF 329 >gi|60460887 solute carrier family 25, member 42 [Homo sapiens] Length = 318 Score = 181 bits (459), Expect = 1e-45 Identities = 100/277 (36%), Positives = 160/277 (57%), Gaps = 8/277 (2%) Query: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTN 257 LL G +AGA+++T+ APLDR KI+ QV + F G SLWRGN Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96 Query: 258 VIKIAPETAVKFWAYEQYKKLLTE----EGQKIGTFERFISGSMAGATAQTFIYPMEVMK 313 ++++ P A++F A+E+YK++L G+ + + R +G++AG TA + YP+++++ Sbjct: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156 Query: 314 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373 R+AV YS I+ +I + EGL Y G++P +LG+IPYAG+ YE LKS Sbjct: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHR 216 Query: 374 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 433 + + P ++ GA + GQ ASYPL +VR RMQ A + G P+ ++ R Sbjct: 217 EYSGRRQPYPFERMIF--GACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273 Query: 434 IISKEG-IPGLYRGITPNFMKVLPAVGISYVVYENMK 469 I+ +EG + GLY+G++ N++K AVGIS+ ++ M+ Sbjct: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310 Score = 75.5 bits (184), Expect = 1e-13 Identities = 55/180 (30%), Positives = 91/180 (50%), Gaps = 6/180 (3%) Query: 195 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGN 254 W +L AG +AG + + T PLD ++ M V K NIF F ++ +E G+++L+ G Sbjct: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAV-TPKEMYSNIFHVFIRISREEGLKTLYHGF 190 Query: 255 GTNVIKIAPETAVKFWAYEQYKKLLTEEG--QKIGTFERFISGSMAGATAQTFIYPMEVM 312 V+ + P + F+ YE K L E ++ FER I G+ AG Q+ YP++V+ Sbjct: 191 MPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVV 250 Query: 313 KTRL-AVGKTG-QYSGIYDCAKKILKHEG-LGAFYKGYVPNLLGIIPYAGIDLAVYELLK 369 + R+ G TG + I + I++ EG + YKG N + GI ++L++ Sbjct: 251 RRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310 Score = 29.6 bits (65), Expect = 6.3 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 392 GALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNF 451 GAL+ + A PL + Q + + + V + + EG L+RG + Sbjct: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97 Query: 452 MKVLPAVGISYVVYENMKQTLG 473 ++V+P I + +E K+ LG Sbjct: 98 VRVVPYAAIQFSAHEEYKRILG 119 >gi|156071462 solute carrier family 25, member A6 [Homo sapiens] Length = 298 Score = 137 bits (345), Expect = 2e-32 Identities = 94/295 (31%), Positives = 155/295 (52%), Gaps = 24/295 (8%) Query: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSK---SDKM--NIFGGFRQMVKEGGIRS 249 + LAGGIA A+S+T+ AP++R+K+++QV H SK +DK I ++ KE G+ S Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69 Query: 250 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 304 WRGN NVI+ P A+ F ++YK++ K F R+ +G++ AGAT+ Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129 Query: 305 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359 F+YP++ +TRLA VGK+G ++ G+ DC KI K +G+ Y+G+ ++ GII Y Sbjct: 130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRA 189 Query: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419 VY+ K D N ++V + + SYP VR RM Q+ Sbjct: 190 AYFGVYDTAK-----GMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGR 244 Query: 420 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472 +G+ + V +R+I EG ++G N ++ + + V+Y+ +K+ + Sbjct: 245 KGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDELKKVI 298 >gi|13775208 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 [Homo sapiens] Length = 315 Score = 132 bits (332), Expect = 7e-31 Identities = 94/294 (31%), Positives = 145/294 (49%), Gaps = 28/294 (9%) Query: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGIR 248 + LLAGG+A AVS+T+ AP++R+K+++QV S S +++ ++ MV +E G Sbjct: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQAS-SKQISPEARYKGMVDCLVRIPREQGFF 80 Query: 249 SLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFI-----SGSMAGATAQ 303 S WRGN NVI+ P A+ F ++YK+L K F R+ SG AGAT+ Sbjct: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140 Query: 304 TFIYPMEVMKTRLAVG-----KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYA 358 +YP++ +TRL V + Q+ G+ DC KI K +G+ Y+G+ ++ GII Y Sbjct: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200 Query: 359 GIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAM 418 Y+ +K K P +V + +TC + SYP VR RM Q+ Sbjct: 201 ASYFGAYDTVKGL----LPKPKKTP-FLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSG 255 Query: 419 LEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVG--ISYVVYENMKQ 470 + F +I EGI +RG F VL G + V+Y+ +K+ Sbjct: 256 EAKRQYKGTLDCFVKIYQHEGISSFFRGA---FSNVLRGTGGALVLVLYDKIKE 306 Score = 57.8 bits (138), Expect = 2e-08 Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 12/196 (6%) Query: 293 ISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ-------YSGIYDCAKKILKHEGLGAFYK 345 ++G +A A ++T + P+E +K L V + + Y G+ DC +I + +G +F++ Sbjct: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWR 84 Query: 346 GYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN-PGVMVLLGCGALSSTCGQLASY 404 G + N++ P ++ A + K ++ K+ + L G + Y Sbjct: 85 GNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVY 144 Query: 405 PLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPAVGIS 461 PL RTR+ + +G + GL +I +GI GLY+G + ++ Sbjct: 145 PLDFARTRLGVD-IGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203 Query: 462 YVVYENMKQTLGVTQK 477 + Y+ +K L +K Sbjct: 204 FGAYDTVKGLLPKPKK 219 >gi|55749577 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 [Homo sapiens] Length = 298 Score = 131 bits (329), Expect = 2e-30 Identities = 93/293 (31%), Positives = 147/293 (50%), Gaps = 24/293 (8%) Query: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSKS-----DKMNIFGGFRQMVKEGGIRS 249 + LAGG+A AVS+T+ AP++R+K+++QV H SK I ++ KE G S Sbjct: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69 Query: 250 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 304 WRGN NVI+ P A+ F ++YK+L + F R+ +G++ AGAT+ Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129 Query: 305 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359 F+YP++ +TRLA VGK ++ G+ DC KI K +GL Y+G+ ++ GII Y Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189 Query: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419 VY+ K D N + V + L SYP VR RM Q+ Sbjct: 190 AYFGVYDTAK-----GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244 Query: 420 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 +G+ + V +R+I EG ++G N ++ + + V+Y+ +K+ Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296 Score = 64.3 bits (155), Expect = 2e-10 Identities = 51/195 (26%), Positives = 86/195 (44%), Gaps = 18/195 (9%) Query: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 344 F++G +A A ++T + P+E +K L V QY GI DC +I K +G +F+ Sbjct: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71 Query: 345 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 400 +G + N++ P ++ A + K +L + G + G +S C Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC-- 129 Query: 401 LASYPLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPA 457 YPL RTR+ A +G+ Q GL +I +G+ GLY+G + ++ Sbjct: 130 -FVYPLDFARTRLAADVG-KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIY 187 Query: 458 VGISYVVYENMKQTL 472 + VY+ K L Sbjct: 188 RAAYFGVYDTAKGML 202 >gi|156071459 solute carrier family 25, member 5 [Homo sapiens] Length = 298 Score = 131 bits (329), Expect = 2e-30 Identities = 90/293 (30%), Positives = 152/293 (51%), Gaps = 24/293 (8%) Query: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSK---SDKM--NIFGGFRQMVKEGGIRS 249 + LAGG+A A+S+T+ AP++R+K+++QV H SK +DK I ++ KE G+ S Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69 Query: 250 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 304 WRGN NVI+ P A+ F ++YK++ K F + +G++ AGAT+ Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129 Query: 305 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359 F+YP++ +TRLA VGK G ++ G+ DC KI K +G+ Y+G+ ++ GII Y Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189 Query: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419 +Y+ K D N +++ + L SYP VR RM Q+ Sbjct: 190 AYFGIYDTAK-----GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGR 244 Query: 420 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 +G+ + + +R+I EG ++G N ++ + + V+Y+ +K+ Sbjct: 245 KGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296 Score = 63.9 bits (154), Expect = 3e-10 Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 16/194 (8%) Query: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 344 F++G +A A ++T + P+E +K L V QY GI DC +I K +G+ +F+ Sbjct: 12 FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71 Query: 345 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 400 +G + N++ P ++ A + K +L K + G + G +S C Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC-- 129 Query: 401 LASYPLALVRTRMQAQAMLEGSPQ--LNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAV 458 YPL RTR+ A G+ + + +I +GI GLY+G + ++ Sbjct: 130 -FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188 Query: 459 GISYVVYENMKQTL 472 + +Y+ K L Sbjct: 189 AAYFGIYDTAKGML 202 >gi|21687151 mitochondrial solute carrier protein [Homo sapiens] Length = 341 Score = 127 bits (319), Expect = 2e-29 Identities = 80/283 (28%), Positives = 145/283 (51%), Gaps = 12/283 (4%) Query: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 255 ++LL G+AG +S + TAPL+ ++ QV + + ++ + G+R+LW+GN Sbjct: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73 Query: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 315 +++ P +AV+ AY ++ L T++ I + ++GS+AG + YP +++KTR Sbjct: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133 Query: 316 LAVGK--TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373 L + Y G+ I + EG A Y+G ++G +P++ L VY L+ W Sbjct: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192 Query: 374 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML---EGSPQLNMVG- 429 N +D + C L++ Q S+P V+ +MQAQ+ G ++ G Sbjct: 193 -NGPRDQFSLPQNFANVC--LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGA 249 Query: 430 --LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 FR+I+ +G+ GL+ G+T N +K++P GI + +E K+ Sbjct: 250 VDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292 Score = 80.5 bits (197), Expect = 3e-15 Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 11/196 (5%) Query: 184 FTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHG-SKSDKMNIFGGFRQMV 242 FT+D QW ++AG +AG VS T P D +K + + + + F + Sbjct: 97 FTDDLGHISQW-SSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIY 155 Query: 243 KEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATA 302 ++ G +L+RG V+ P +A Y +K+ + + F + +A A Sbjct: 156 QQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVT 215 Query: 303 QTFIYPMEVMKTRLAV---------GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLG 353 QT +P E +K ++ G +SG DC ++I+K +G+ + G NLL Sbjct: 216 QTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275 Query: 354 IIPYAGIDLAVYELLK 369 I+PY GI + +E K Sbjct: 276 IVPYFGIMFSTFEFCK 291 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 8/84 (9%) Query: 203 IAGAVSRTSTAPLDRLKIMMQVHGS---KSDKMNI-FGG----FRQMVKEGGIRSLWRGN 254 +A AV++T + P + +K MQ S +++ F G FRQ+VK G+ LW G Sbjct: 210 LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGL 269 Query: 255 GTNVIKIAPETAVKFWAYEQYKKL 278 N++KI P + F +E K++ Sbjct: 270 TANLLKIVPYFGIMFSTFEFCKRI 293 >gi|21314739 solute carrier family 25, member 32 [Homo sapiens] Length = 315 Score = 119 bits (297), Expect = 8e-27 Identities = 86/290 (29%), Positives = 132/290 (45%), Gaps = 17/290 (5%) Query: 195 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV---KEGGIRSLW 251 + L+AG G +S + PLD +KI V + G + K G+R L+ Sbjct: 23 YENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLY 82 Query: 252 RGNGTNVIKIAPETAVKFWAYEQYKKLLTE-EGQKIGTFERFISGSMAGATAQTFIYPME 310 +G N+ + F+ Y K TE +++ E +S + AGA P+ Sbjct: 83 QGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLW 142 Query: 311 VMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLA 363 V KTRL + QY G++D KI K+EG+ YKG+VP L G + + Sbjct: 143 VTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFM 201 Query: 364 VYELLKSYWLDNFAK-DSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGS 422 YELLK + + + + + ALS A+YP +VR R+Q Q M Sbjct: 202 AYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG 261 Query: 423 PQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472 ++ + + KEG+ G Y+GI PN ++V PA I++VVYEN+ L Sbjct: 262 ----VIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307 Score = 65.9 bits (159), Expect = 8e-11 Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 13/188 (6%) Query: 198 LLAGGIAGAVSRTSTAPL--DRLKIMMQ----VHGSKSDKMNIFGGFRQMVKEGGIRSLW 251 L++ AGA++ T PL + ++M+Q V+ +F ++ K G+R L+ Sbjct: 124 LVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLY 183 Query: 252 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKI-----GTFERFISGSMAGATAQTFI 306 +G + + A++F AYE K + ++ T E +++ A Sbjct: 184 KGFVPGLFGTS-HGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAAT 242 Query: 307 YPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE 366 YP +V++ RL + YSG+ D K + EG+G FYKG PNL+ + P I VYE Sbjct: 243 YPYQVVRARLQ-DQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYE 301 Query: 367 LLKSYWLD 374 + + LD Sbjct: 302 NVSHFLLD 309 >gi|186928856 solute carrier family 25, member 19 [Homo sapiens] Length = 320 Score = 109 bits (273), Expect = 5e-24 Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%) Query: 199 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 251 +AG ++G V+R +P D +KI Q+ S+SD + G RQ+++E G + W Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79 Query: 252 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 308 +G+ I AV+F ++E +L+ G E F+ G +A A ++P Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138 Query: 309 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 367 ++V++TR A G+ Y+ + + + EG FYKG P L+ I PYAG+ + Y Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198 Query: 368 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 426 LK Y A+ N + LL CG+ + + +YPL L + R+Q Sbjct: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257 Query: 427 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466 V + ++++ KEG G ++G++P+ +K + G + YE Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304 Score = 77.0 bits (188), Expect = 3e-14 Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%) Query: 282 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 333 +G+ F+ ++GS++G + I P +V+K R + + +Y GI +++ Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68 Query: 334 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 393 IL+ EG AF+KG+VP + I Y + +E+L D+ V + CG Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126 Query: 394 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 448 L++ L +P+ ++RTR AQ G P++ + VG R EG Y+G+ Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179 Query: 449 PNFMKVLPAVGISYVVYENMK 469 P + + P G+ + Y ++K Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%) Query: 188 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 239 E K + + LL G AG +S+T T PLD K +QV G + + FG R Sbjct: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268 Query: 240 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 273 Q++++ G ++G +++K A T F++YE Sbjct: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304 >gi|186928860 solute carrier family 25, member 19 [Homo sapiens] Length = 320 Score = 109 bits (273), Expect = 5e-24 Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%) Query: 199 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 251 +AG ++G V+R +P D +KI Q+ S+SD + G RQ+++E G + W Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79 Query: 252 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 308 +G+ I AV+F ++E +L+ G E F+ G +A A ++P Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138 Query: 309 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 367 ++V++TR A G+ Y+ + + + EG FYKG P L+ I PYAG+ + Y Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198 Query: 368 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 426 LK Y A+ N + LL CG+ + + +YPL L + R+Q Sbjct: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257 Query: 427 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466 V + ++++ KEG G ++G++P+ +K + G + YE Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304 Score = 77.0 bits (188), Expect = 3e-14 Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%) Query: 282 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 333 +G+ F+ ++GS++G + I P +V+K R + + +Y GI +++ Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68 Query: 334 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 393 IL+ EG AF+KG+VP + I Y + +E+L D+ V + CG Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126 Query: 394 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 448 L++ L +P+ ++RTR AQ G P++ + VG R EG Y+G+ Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179 Query: 449 PNFMKVLPAVGISYVVYENMK 469 P + + P G+ + Y ++K Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%) Query: 188 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 239 E K + + LL G AG +S+T T PLD K +QV G + + FG R Sbjct: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268 Query: 240 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 273 Q++++ G ++G +++K A T F++YE Sbjct: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304 >gi|186928858 solute carrier family 25, member 19 [Homo sapiens] Length = 320 Score = 109 bits (273), Expect = 5e-24 Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%) Query: 199 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 251 +AG ++G V+R +P D +KI Q+ S+SD + G RQ+++E G + W Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79 Query: 252 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 308 +G+ I AV+F ++E +L+ G E F+ G +A A ++P Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138 Query: 309 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 367 ++V++TR A G+ Y+ + + + EG FYKG P L+ I PYAG+ + Y Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198 Query: 368 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 426 LK Y A+ N + LL CG+ + + +YPL L + R+Q Sbjct: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257 Query: 427 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466 V + ++++ KEG G ++G++P+ +K + G + YE Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304 Score = 77.0 bits (188), Expect = 3e-14 Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%) Query: 282 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 333 +G+ F+ ++GS++G + I P +V+K R + + +Y GI +++ Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68 Query: 334 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 393 IL+ EG AF+KG+VP + I Y + +E+L D+ V + CG Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126 Query: 394 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 448 L++ L +P+ ++RTR AQ G P++ + VG R EG Y+G+ Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179 Query: 449 PNFMKVLPAVGISYVVYENMK 469 P + + P G+ + Y ++K Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%) Query: 188 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 239 E K + + LL G AG +S+T T PLD K +QV G + + FG R Sbjct: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268 Query: 240 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 273 Q++++ G ++G +++K A T F++YE Sbjct: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304 >gi|157388989 solute carrier family 25, member 36 isoform a [Homo sapiens] Length = 311 Score = 108 bits (270), Expect = 1e-23 Identities = 82/299 (27%), Positives = 135/299 (45%), Gaps = 35/299 (11%) Query: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS----KSDKMNIFGG--------------FR 239 L AGG G V T PL+ +K +Q ++N G + Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69 Query: 240 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 299 ++++ G RSL+RG G N++ +AP A+ F AY K+ L + T IS +MAG Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129 Query: 300 ATAQTFIYPMEVMKTRL---AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIP 356 TA T P+ ++KTRL A + + G ++C +K+ + +GL FY+G + GI Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189 Query: 357 YAGIDLAVYELLKSYWLDNFAKDSVN---------PGVMVLLGCGALSSTCGQLASYPLA 407 I +YE +K L+ ++ + ++ A S TC +YP Sbjct: 190 TV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHE 248 Query: 408 LVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466 +VRTR++ EG+ + ++ +EG LYRG+T + ++ +P I YE Sbjct: 249 VVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 303 Score = 80.1 bits (196), Expect = 4e-15 Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 24/204 (11%) Query: 288 TFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQY-------------------SGIY 328 T +G G P+EV+KTRL Y G Sbjct: 6 TLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPL 65 Query: 329 DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVL 388 C K IL+ EG + ++G PNL+G+ P I A Y K D F DS V Sbjct: 66 HCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS----TQVH 121 Query: 389 LGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGIT 448 + A++ A+ P+ L++TR+Q A G ++ R++ +G+ G YRG++ Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181 Query: 449 PNFMKVLPAVGISYVVYENMKQTL 472 ++ + V I +V+YE++KQ L Sbjct: 182 ASYAGISETV-IHFVIYESIKQKL 204 Score = 68.9 bits (167), Expect = 9e-12 Identities = 50/186 (26%), Positives = 89/186 (47%), Gaps = 17/186 (9%) Query: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSD--KMNIFGGFRQMVKEGGIRSLWRGNG 255 +++ +AG + T+T P+ +K +Q+ +M F R++ + G++ +RG Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181 Query: 256 TNVIKIAPETAVKFWAYEQYKKLLTE---------EGQKIGTFERFISGSMAGAT----A 302 + I+ ET + F YE K+ L E + + + F+ +A AT A Sbjct: 182 ASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240 Query: 303 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362 T YP EV++TRL T +Y + +++ EG G+ Y+G +L+ IP I + Sbjct: 241 TTIAYPHEVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMM 299 Query: 363 AVYELL 368 A YEL+ Sbjct: 300 ATYELV 305 Score = 35.4 bits (80), Expect = 0.11 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Query: 186 EDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEG 245 E K++ + +LA + + T P + ++ ++ G+K + F +V+E Sbjct: 218 ESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKY--RSFFQTLSLLVQEE 275 Query: 246 GIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLL 279 G SL+RG T++++ P TA+ YE LL Sbjct: 276 GYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 309 >gi|157388991 solute carrier family 25, member 36 isoform b [Homo sapiens] Length = 310 Score = 104 bits (260), Expect = 2e-22 Identities = 82/299 (27%), Positives = 135/299 (45%), Gaps = 36/299 (12%) Query: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS----KSDKMNIFGG--------------FR 239 L AGG G V T PL+ +K +Q ++N G + Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69 Query: 240 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 299 ++++ G RSL+RG G N++ +AP A+ F AY K+ L + T IS +MAG Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129 Query: 300 ATAQTFIYPMEVMKTRL---AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIP 356 TA T P+ ++KTRL A + + G ++C +K+ + +GL FY+G + GI Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189 Query: 357 YAGIDLAVYELLKSYWLDNFAKDSVN---------PGVMVLLGCGALSSTCGQLASYPLA 407 I +YE +K L+ ++ + ++ A S TC +YP Sbjct: 190 TV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-H 247 Query: 408 LVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466 +VRTR++ EG+ + ++ +EG LYRG+T + ++ +P I YE Sbjct: 248 VVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302 Score = 80.1 bits (196), Expect = 4e-15 Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 24/204 (11%) Query: 288 TFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQY-------------------SGIY 328 T +G G P+EV+KTRL Y G Sbjct: 6 TLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPL 65 Query: 329 DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVL 388 C K IL+ EG + ++G PNL+G+ P I A Y K D F DS V Sbjct: 66 HCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS----TQVH 121 Query: 389 LGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGIT 448 + A++ A+ P+ L++TR+Q A G ++ R++ +G+ G YRG++ Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181 Query: 449 PNFMKVLPAVGISYVVYENMKQTL 472 ++ + V I +V+YE++KQ L Sbjct: 182 ASYAGISETV-IHFVIYESIKQKL 204 Score = 63.2 bits (152), Expect = 5e-10 Identities = 49/186 (26%), Positives = 88/186 (47%), Gaps = 18/186 (9%) Query: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSD--KMNIFGGFRQMVKEGGIRSLWRGNG 255 +++ +AG + T+T P+ +K +Q+ +M F R++ + G++ +RG Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181 Query: 256 TNVIKIAPETAVKFWAYEQYKKLLTE---------EGQKIGTFERFISGSMAGAT----A 302 + I+ ET + F YE K+ L E + + + F+ +A AT A Sbjct: 182 ASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240 Query: 303 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362 T YP V++TRL T +Y + +++ EG G+ Y+G +L+ IP I + Sbjct: 241 TTIAYP-HVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMM 298 Query: 363 AVYELL 368 A YEL+ Sbjct: 299 ATYELV 304 Score = 30.8 bits (68), Expect = 2.8 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Query: 186 EDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEG 245 E K++ + +LA + + T P ++ ++ G+K + F +V+E Sbjct: 218 ESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKY--RSFFQTLSLLVQEE 274 Query: 246 GIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLL 279 G SL+RG T++++ P TA+ YE LL Sbjct: 275 GYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 308 >gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo sapiens] Length = 325 Score = 104 bits (260), Expect = 2e-22 Identities = 77/296 (26%), Positives = 130/296 (43%), Gaps = 14/296 (4%) Query: 185 TEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-------NIFGG 237 T + SG W+ + GG+A V+ T P+D K +QV G D +F Sbjct: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90 Query: 238 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 297 ++ KE G+ +L+ G +++ A +K Y+ K+L E + I G + Sbjct: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVV 150 Query: 298 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 357 +G + T P +V+K R+ + + I + EG ++G VP Sbjct: 151 SGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIV 210 Query: 358 AGIDLAVYELLKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 416 G++L VY++ K + L D++ + CG G LAS P+ +VRTRM Q Sbjct: 211 VGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQ 266 Query: 417 AMLEGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 + G L V ++ EG LY+G PN++++ P I ++ YE +K+ Sbjct: 267 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322 Score = 88.6 bits (218), Expect = 1e-17 Identities = 56/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%) Query: 292 FISGSMAGATAQTFIYPMEVMKTRLAVG--------KTGQYSGIYDCAKKILKHEGLGAF 343 F+ G +A A+ +P+++ KTRL V K +Y G++ +I K EG+ A Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103 Query: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403 Y G P LL Y I + +Y+ LK +++ ++ +++ + CG +S + Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDET----LLINMICGVVSGVISSTIA 159 Query: 404 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 463 P +++ RMQAQ L Q +M+G F I +EG GL+RG+ P + VG+ Sbjct: 160 NPTDVLKIRMQAQGSLF---QGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 216 Query: 464 VYENMKQTL 472 VY+ K+ L Sbjct: 217 VYDITKKHL 225 Score = 31.6 bits (70), Expect = 1.7 Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 7/81 (8%) Query: 202 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF----GGFRQMVKEGGIRSLWRGNGTN 257 G+AGA++ P+D ++ M + ++++ G +M K G +L++G N Sbjct: 246 GLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPN 302 Query: 258 VIKIAPETAVKFWAYEQYKKL 278 +++ P + F YEQ K+L Sbjct: 303 WLRLGPWNIIFFITYEQLKRL 323 >gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo sapiens] Length = 322 Score = 104 bits (260), Expect = 2e-22 Identities = 77/296 (26%), Positives = 130/296 (43%), Gaps = 14/296 (4%) Query: 185 TEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-------NIFGG 237 T + SG W+ + GG+A V+ T P+D K +QV G D +F Sbjct: 28 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 87 Query: 238 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 297 ++ KE G+ +L+ G +++ A +K Y+ K+L E + I G + Sbjct: 88 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVV 147 Query: 298 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 357 +G + T P +V+K R+ + + I + EG ++G VP Sbjct: 148 SGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIV 207 Query: 358 AGIDLAVYELLKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 416 G++L VY++ K + L D++ + CG G LAS P+ +VRTRM Q Sbjct: 208 VGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQ 263 Query: 417 AMLEGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 + G L V ++ EG LY+G PN++++ P I ++ YE +K+ Sbjct: 264 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319 Score = 88.6 bits (218), Expect = 1e-17 Identities = 56/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%) Query: 292 FISGSMAGATAQTFIYPMEVMKTRLAVG--------KTGQYSGIYDCAKKILKHEGLGAF 343 F+ G +A A+ +P+++ KTRL V K +Y G++ +I K EG+ A Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100 Query: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403 Y G P LL Y I + +Y+ LK +++ ++ +++ + CG +S + Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDET----LLINMICGVVSGVISSTIA 156 Query: 404 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 463 P +++ RMQAQ L Q +M+G F I +EG GL+RG+ P + VG+ Sbjct: 157 NPTDVLKIRMQAQGSLF---QGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 213 Query: 464 VYENMKQTL 472 VY+ K+ L Sbjct: 214 VYDITKKHL 222 Score = 31.6 bits (70), Expect = 1.7 Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 7/81 (8%) Query: 202 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF----GGFRQMVKEGGIRSLWRGNGTN 257 G+AGA++ P+D ++ M + ++++ G +M K G +L++G N Sbjct: 243 GLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPN 299 Query: 258 VIKIAPETAVKFWAYEQYKKL 278 +++ P + F YEQ K+L Sbjct: 300 WLRLGPWNIIFFITYEQLKRL 320 >gi|21361103 solute carrier family 25, member 12 [Homo sapiens] Length = 678 Score = 102 bits (254), Expect = 8e-22 Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 5/183 (2%) Query: 197 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 256 ++LAGG AG T PL+ +KI +QV G + + ++++ GI L++G Sbjct: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--LNVLRDLGIFGLYKGAKA 486 Query: 257 NVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRL 316 ++ P +A+ F Y K LL +E +G +G+MAG A + + P +V+KTRL Sbjct: 487 CFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL 546 Query: 317 AVG-KTGQ--YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373 V + GQ YSG+ DC +KIL+ EG AF+KG + P G+ L YELL+ ++ Sbjct: 547 QVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFY 606 Query: 374 DNF 376 +F Sbjct: 607 IDF 609 Score = 98.2 bits (243), Expect = 1e-20 Identities = 72/277 (25%), Positives = 126/277 (45%), Gaps = 13/277 (4%) Query: 201 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM------NIFGGFRQMVKEGGIRSLWRGN 254 G +AGAV T+ P+D +K MQ + N F F+++++ G L+RG Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392 Query: 255 GTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKT 314 +I +APE A+K + + T + ++G AG + F P+E++K Sbjct: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452 Query: 315 RLAVGKTGQY-SGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373 RL V G+ +G A +L+ G+ YKG L IP++ I VY K Sbjct: 453 RLQV--AGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLL-- 508 Query: 374 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 433 A ++ + G + LL GA++ P +++TR+Q A + ++ FR+ Sbjct: 509 --LADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRK 566 Query: 434 IISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 I+ +EG ++G + P G++ V YE +++ Sbjct: 567 ILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603 Score = 92.4 bits (228), Expect = 8e-19 Identities = 110/469 (23%), Positives = 200/469 (42%), Gaps = 78/469 (16%) Query: 28 FQALDRNGDGVVDIGELQE----GLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKY 83 FQ D++G+G V ++E + + IP D E G N+ L++ EF ++ Sbjct: 95 FQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGH-NRKKHLNYTEFTQF 153 Query: 84 LKDHE-KKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTV 142 L++ + + + AF DK+ G I + + T+ S + +++ ++ Sbjct: 154 LQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIR---SHMLTPFVEENLVSAAGGSI 210 Query: 143 DWNEWRDYF-LFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAG 201 YF FN + + E++R + D +EF + + GQ Sbjct: 211 SHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQ-------- 262 Query: 202 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKI 261 PL+ + I+ Q+ +D N G R ++ +I Sbjct: 263 ----------VTPLE-IDILYQL----ADLYNASG---------------RLTLADIERI 292 Query: 262 AP--ETAVKFWAYEQYKKLLTEEGQKIG-----TFERFISGSMAGATAQTFIYPMEVMKT 314 AP E A+ + E ++ G+ I + RF GS+AGA T +YP++++KT Sbjct: 293 APLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKT 352 Query: 315 RL--------AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE 366 R+ VG+ Y +DC KK+L++EG Y+G +P L+G+ P I L V + Sbjct: 353 RMQNQRGSGSVVGEL-MYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVND 411 Query: 367 LLKSYWLDNFAKDSVN---PGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSP 423 ++ D F + + P ++ GC S + + PL +V+ R+Q + P Sbjct: 412 FVR----DKFTRRDGSVPLPAEVLAGGCAGGSQV---IFTNPLEIVKIRLQVAGEITTGP 464 Query: 424 QLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472 +++ + + R + GI GLY+G F++ +P I + VY + K L Sbjct: 465 RVSALNVLRDL----GIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL 509 >gi|46094065 mitochondrial carrier family protein [Homo sapiens] Length = 338 Score = 100 bits (249), Expect = 3e-21 Identities = 75/309 (24%), Positives = 136/309 (44%), Gaps = 41/309 (13%) Query: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF---------------GG--- 237 +Q+LA ++ PLD +KI +Q + K F GG Sbjct: 17 QQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKL 76 Query: 238 --------------FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEG 283 F ++++ GI+SLW G ++ P T + F Y+Q LL + Sbjct: 77 WYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKL 136 Query: 284 QKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAF 343 + T ++G +A A T I P+E+++T++ K Y ++ K + +G + Sbjct: 137 GENETCIPIVAGIVARFGAVTVISPLELIRTKMQ-SKKFSYVELHRFVSKKVSEDGWISL 195 Query: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403 ++G+ P +L +P++ + YE+LK + + P M+ GALS + +A+ Sbjct: 196 WRGWAPTVLRDVPFSAMYWYNYEILKKWLCEK--SGLYEPTFMINFTSGALSGSFAAVAT 253 Query: 404 YPLALVRTRMQAQAMLEGSPQLNMV------GLFRRIISKEGIPGLYRGITPNFMKVLPA 457 P +V+T+ Q Q S +++M + + I++K G GL+ G+ P +K+ PA Sbjct: 254 LPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPA 313 Query: 458 VGISYVVYE 466 I YE Sbjct: 314 CAIMISTYE 322 Score = 63.9 bits (154), Expect = 3e-10 Identities = 51/188 (27%), Positives = 85/188 (45%), Gaps = 23/188 (12%) Query: 203 IAGAVSR----TSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 258 +AG V+R T +PL+ ++ MQ K + + + V E G SLWRG V Sbjct: 146 VAGIVARFGAVTVISPLELIRTKMQ--SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTV 203 Query: 259 IKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE-----RFISGSMAGATAQTFIYPMEVMK 313 ++ P +A+ ++ YE KK L E K G +E F SG+++G+ A P +V+K Sbjct: 204 LRDVPFSAMYWYNYEILKKWLCE---KSGLYEPTFMINFTSGALSGSFAAVATLPFDVVK 260 Query: 314 TRLAVG---------KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAV 364 T+ + + K I+ G + G +P L+ I P I ++ Sbjct: 261 TQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIST 320 Query: 365 YELLKSYW 372 YE K+++ Sbjct: 321 YEFGKAFF 328 Score = 53.1 bits (126), Expect = 5e-07 Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 22/160 (13%) Query: 320 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE----LLKSYWLDN 375 K G + G D KI+++EG+ + + G P L+ +P I Y+ LL+S +N Sbjct: 80 KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGEN 139 Query: 376 FAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRI- 434 + G++ G + S PL L+RT+MQ S + + V L R + Sbjct: 140 ETCIPIVAGIVARFGAVTVIS--------PLELIRTKMQ-------SKKFSYVELHRFVS 184 Query: 435 --ISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472 +S++G L+RG P ++ +P + + YE +K+ L Sbjct: 185 KKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL 224 >gi|58197562 solute carrier family 25, member 30 [Homo sapiens] Length = 291 Score = 98.2 bits (243), Expect = 1e-20 Identities = 73/287 (25%), Positives = 124/287 (43%), Gaps = 15/287 (5%) Query: 195 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGI 247 W+ + GG+A + T P+D K +Q+ G +D +R M+ +E G+ Sbjct: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65 Query: 248 RSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIY 307 ++L+ G +++ A +K Y+ K+L E + I G ++G + T Sbjct: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125 Query: 308 PMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 367 P +V+K R+ G+ I + EG +KG G++L VY++ Sbjct: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185 Query: 368 LKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 426 K + L D+V + CG G LAS P+ +VRTRM Q +L Sbjct: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241 Query: 427 MVGLFRRII---SKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470 G ++ EG LY+G PN++++ P I +V YE +K+ Sbjct: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288 Score = 83.6 bits (205), Expect = 4e-16 Identities = 55/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%) Query: 292 FISGSMAGATAQTFIYPMEVMKTRLAV-GKTG-------QYSGIYDCAKKILKHEGLGAF 343 F+ G +A TA+ +P+++ KTRL + G+T +Y G+ +I + EGL A Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68 Query: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403 Y G P +L Y I + Y+ LK +++ +++ V+ CG LS + Sbjct: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVI----CGILSGVISSTIA 124 Query: 404 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 463 P +++ RMQAQ+ + Q M+G F I +EG GL++G++ + VG+ Sbjct: 125 NPTDVLKIRMQAQS---NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELP 181 Query: 464 VYENMKQTL 472 VY+ K+ L Sbjct: 182 VYDITKKHL 190 >gi|82775373 solute carrier family 25, member 37 [Homo sapiens] Length = 338 Score = 97.4 bits (241), Expect = 2e-20 Identities = 79/289 (27%), Positives = 128/289 (44%), Gaps = 24/289 (8%) Query: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS--KSDKMNIFGGFRQMVKEGGIRSLWRGNG 255 + AG +AG + + P+D +K MQ K+ +I+G +++++ G RG Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108 Query: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGT--FERFISGSMAGATAQTFIYPMEVMK 313 ++ P A+ F YE K+ L + G I+GSMA + P EV+K Sbjct: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVK 168 Query: 314 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373 RL + + S I C + + + EGLGAFY+ Y L IP+ I YE Sbjct: 169 QRLQMYNSQHRSAI-SCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE------- 220 Query: 374 DNFAKDSVNP----GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ-----AMLEGSPQ 424 F ++ VNP + G L+ A+ PL + +T + Q ++ S + Sbjct: 221 --FLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR 278 Query: 425 LN-MVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472 L+ M FR + G+ G ++GI + +P+ IS+ VYE K L Sbjct: 279 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 8/92 (8%) Query: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-NIFG-------GFRQMVKEGGIRS 249 +++GG+AGA++ +T PLD K ++ + + + NI G FR + + G+ Sbjct: 238 IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAG 297 Query: 250 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTE 281 ++G VI P TA+ + YE +K LT+ Sbjct: 298 YFKGIQARVIYQMPSTAISWSVYEFFKYFLTK 329 >gi|7706306 solute carrier family 25, member 39 isoform b [Homo sapiens] Length = 351 Score = 97.4 bits (241), Expect = 2e-20 Identities = 65/236 (27%), Positives = 112/236 (47%), Gaps = 11/236 (4%) Query: 238 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 297 F ++V+ G R+LW G ++ P TA+ F AY+Q K L + ++G++ Sbjct: 103 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGAL 162 Query: 298 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 357 A T I P+E+M+T+L Y + C + + G + + G+ P L +P+ Sbjct: 163 ARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 221 Query: 358 AGIDLAVYELLKSYWLDNF-AKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 416 + + YEL+KS WL+ F KD + G+ + G +S T + + P +V+T+ Q Sbjct: 222 SALYWFNYELVKS-WLNGFRPKDQTSVGMSFV--AGGISGTVAAVLTLPFDVVKTQRQVA 278 Query: 417 AMLEGSPQLNMVG------LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466 + ++N + L RRI ++ G GL+ G P +K P+ I YE Sbjct: 279 LGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334 Score = 59.3 bits (142), Expect = 7e-09 Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 17/190 (8%) Query: 198 LLAGGIAGAVSRTST----APLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 253 L A +AGA++R T +PL+ ++ +Q ++ R V +GG RSLW G Sbjct: 153 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGAC--VRTAVAQGGWRSLWLG 210 Query: 254 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE--RFISGSMAGATAQTFIYPMEV 311 G ++ P +A+ ++ YE K L K T F++G ++G A P +V Sbjct: 211 WGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDV 270 Query: 312 MKTRLAVGKTGQYS---------GIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362 +KT+ V + + ++I G + G++P ++ P I + Sbjct: 271 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 330 Query: 363 AVYELLKSYW 372 + YE KS++ Sbjct: 331 STYEFGKSFF 340 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,756,581 Number of Sequences: 37866 Number of extensions: 724721 Number of successful extensions: 3184 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 166 Number of HSP's successfully gapped in prelim test: 92 Number of HSP's that attempted gapping in prelim test: 1970 Number of HSP's gapped (non-prelim): 684 length of query: 477 length of database: 18,247,518 effective HSP length: 106 effective length of query: 371 effective length of database: 14,233,722 effective search space: 5280710862 effective search space used: 5280710862 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.