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Search of human proteins with 148352329
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]
(436 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens] 871 0.0
gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens] 867 0.0
gi|4758942 septin 4 isoform 1 [Homo sapiens] 384 e-107
gi|17986247 septin 4 isoform 3 [Homo sapiens] 384 e-107
gi|9945439 septin 5 [Homo sapiens] 380 e-105
gi|56549640 septin 2 [Homo sapiens] 377 e-105
gi|56549638 septin 2 [Homo sapiens] 377 e-105
gi|56549636 septin 2 [Homo sapiens] 377 e-105
gi|4758158 septin 2 [Homo sapiens] 377 e-105
gi|16604248 septin 1 [Homo sapiens] 349 3e-96
gi|149363638 septin 8 isoform c [Homo sapiens] 327 2e-89
gi|149363689 septin 8 isoform a [Homo sapiens] 325 4e-89
gi|149363661 septin 8 isoform b [Homo sapiens] 325 4e-89
gi|8922712 septin 11 [Homo sapiens] 322 4e-88
gi|22035581 septin 6 isoform D [Homo sapiens] 315 7e-86
gi|21361478 septin 6 isoform B [Homo sapiens] 313 2e-85
gi|22035579 septin 6 isoform A [Homo sapiens] 313 2e-85
gi|22035577 septin 6 isoform A [Homo sapiens] 313 2e-85
gi|30795193 septin 10 isoform 2 [Homo sapiens] 309 3e-84
gi|21945064 septin 10 isoform 1 [Homo sapiens] 309 3e-84
gi|156602655 septin 3 isoform A [Homo sapiens] 308 6e-84
gi|156602653 septin 3 isoform B [Homo sapiens] 308 6e-84
gi|164698504 septin 9 isoform f [Homo sapiens] 306 2e-83
gi|164698502 septin 9 isoform d [Homo sapiens] 306 2e-83
gi|164698500 septin 9 isoform e [Homo sapiens] 306 2e-83
gi|164698498 septin 9 isoform b [Homo sapiens] 306 2e-83
gi|164698496 septin 9 isoform e [Homo sapiens] 306 2e-83
gi|164698494 septin 9 isoform a [Homo sapiens] 306 2e-83
gi|116256489 septin 9 isoform c [Homo sapiens] 306 2e-83
gi|153252198 septin 14 [Homo sapiens] 305 7e-83
>gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]
Length = 436
Score = 871 bits (2251), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MSVSARSAAAEERSVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGL 60
MSVSARSAAAEERSVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGL
Sbjct: 1 MSVSARSAAAEERSVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGL 60
Query: 61 GKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAV 120
GKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAV
Sbjct: 61 GKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAV 120
Query: 121 DNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMK 180
DNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMK
Sbjct: 121 DNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMK 180
Query: 181 RLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIK 240
RLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIK
Sbjct: 181 RLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIK 240
Query: 241 DRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVT 300
DRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVT
Sbjct: 241 DRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVT 300
Query: 301 NNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVF 360
NNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVF
Sbjct: 301 NNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVF 360
Query: 361 EMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQ 420
EMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQ
Sbjct: 361 EMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQ 420
Query: 421 NSSRTLEKNKKKGKIF 436
NSSRTLEKNKKKGKIF
Sbjct: 421 NSSRTLEKNKKKGKIF 436
>gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]
Length = 437
Score = 867 bits (2239), Expect = 0.0
Identities = 436/437 (99%), Positives = 436/437 (99%), Gaps = 1/437 (0%)
Query: 1 MSVSARSAAAEERSVNSSTM-AQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESG 59
MSVSARSAAAEERSVNSSTM AQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESG
Sbjct: 1 MSVSARSAAAEERSVNSSTMVAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESG 60
Query: 60 LGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDA 119
LGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDA
Sbjct: 61 LGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDA 120
Query: 120 VDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFM 179
VDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFM
Sbjct: 121 VDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFM 180
Query: 180 KRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKI 239
KRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKI
Sbjct: 181 KRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKI 240
Query: 240 KDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDV 299
KDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDV
Sbjct: 241 KDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDV 300
Query: 300 TNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQV 359
TNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQV
Sbjct: 301 TNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQV 360
Query: 360 FEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQ 419
FEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQ
Sbjct: 361 FEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQ 420
Query: 420 QNSSRTLEKNKKKGKIF 436
QNSSRTLEKNKKKGKIF
Sbjct: 421 QNSSRTLEKNKKKGKIF 437
>gi|4758942 septin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 384 bits (987), Expect = e-107
Identities = 191/364 (52%), Positives = 257/364 (70%), Gaps = 14/364 (3%)
Query: 29 YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 87
YVGFA LPNQV+RKSVK+GF+FTLMV GESGLGKSTL+NSLFLTDLY + G RI
Sbjct: 124 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 183
Query: 88 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147
+TV++ + V I+E GV+L LTIVDTPGFGDAV+N+ CW+PV +YID +FE Y ES +
Sbjct: 184 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 243
Query: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207
NR+ + DNRV CCLYFI+P GHGL+PLD+EFMK LH++VNI+P++AKADTLTP E K
Sbjct: 244 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 303
Query: 208 KQIMKEIQEHKIKIYEFPETDDEEENKLV---KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
++I +EI+ IKIY+FP+ D +E+ + +K+ +P AV+GSNT++E G+RVRGR
Sbjct: 304 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 363
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNN 324
YPWG+ EVEN HCDF LR ML+RTHMQDLKDVT HYENYR++ + ++T V
Sbjct: 364 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMT-RLVVKE 422
Query: 325 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQ 384
+N+ +LT+ + + + E ++EK ++L+ + L + +Q
Sbjct: 423 RNRNKLTRESGTDF---------PIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQ 473
Query: 385 MKKN 388
MK+N
Sbjct: 474 MKEN 477
>gi|17986247 septin 4 isoform 3 [Homo sapiens]
Length = 459
Score = 384 bits (987), Expect = e-107
Identities = 191/364 (52%), Positives = 257/364 (70%), Gaps = 14/364 (3%)
Query: 29 YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 87
YVGFA LPNQV+RKSVK+GF+FTLMV GESGLGKSTL+NSLFLTDLY + G RI
Sbjct: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
Query: 88 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147
+TV++ + V I+E GV+L LTIVDTPGFGDAV+N+ CW+PV +YID +FE Y ES +
Sbjct: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
Query: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207
NR+ + DNRV CCLYFI+P GHGL+PLD+EFMK LH++VNI+P++AKADTLTP E K
Sbjct: 225 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 284
Query: 208 KQIMKEIQEHKIKIYEFPETDDEEENKLV---KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
++I +EI+ IKIY+FP+ D +E+ + +K+ +P AV+GSNT++E G+RVRGR
Sbjct: 285 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 344
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNN 324
YPWG+ EVEN HCDF LR ML+RTHMQDLKDVT HYENYR++ + ++T V
Sbjct: 345 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMT-RLVVKE 403
Query: 325 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQ 384
+N+ +LT+ + + + E ++EK ++L+ + L + +Q
Sbjct: 404 RNRNKLTRESGTDF---------PIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQ 454
Query: 385 MKKN 388
MK+N
Sbjct: 455 MKEN 458
>gi|9945439 septin 5 [Homo sapiens]
Length = 369
Score = 380 bits (977), Expect = e-105
Identities = 187/345 (54%), Positives = 250/345 (72%), Gaps = 5/345 (1%)
Query: 29 YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 87
YVGFA LPNQV+RKSVK+GF+FTLMV GESGLGKSTL++SLFLTDLY + RI
Sbjct: 24 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
Query: 88 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147
+TV++ + V I+E GV+L LTIVDTPGFGDAV+N+ CW+P+ DY+D +FE Y ES +
Sbjct: 84 QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
Query: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207
NR+ + DNRV CCLYFI+P GHGL+P+D+ FMK LHEKVNI+PLIAKAD L P E ++ K
Sbjct: 144 NRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
Query: 208 KQIMKEIQEHKIKIYEFPETD---DEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
++I +EI + I +Y+FPE D DE+ + +++K+ P AV+GSNT++E G+RVRGR
Sbjct: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNN 324
YPWG+ EVEN HCDF LRNMLIRTHM DLKDVT +VHYENYR+ + +T ++
Sbjct: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323
Query: 325 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQ 369
+ + + PL + E E + +MK E+ Q ++K+++Q
Sbjct: 324 RMESPIPILPLPTPDAE-TEKLIRMKDEELRRMQEMLQRMKQQMQ 367
>gi|56549640 septin 2 [Homo sapiens]
Length = 361
Score = 377 bits (969), Expect = e-105
Identities = 194/336 (57%), Positives = 255/336 (75%), Gaps = 9/336 (2%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPE--YPGPSHR 85
GYVGFANLPNQV+RKSVK+GFEFTLMVVGESGLGKSTLINSLFLTDLY PE PG + +
Sbjct: 16 GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLY-PERVIPGAAEK 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
I++TVQ+E S V I+E GV+L LT+VDTPG+GDA++ +C++ +I YID +FE YL+ ES
Sbjct: 75 IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDES 134
Query: 146 RVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NRR + DNRV CC YFI+P GHGLKPLD+ FMK +H KVNI+P+IAKADTLT +E ++
Sbjct: 135 GLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERER 194
Query: 206 FKKQIMKEIQEHKIKIYEFPET---DDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVR 262
KK+I+ EI+EH IKIY P+ +DE+ + + +K +P +VVGSN +IE GK+VR
Sbjct: 195 LKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVR 254
Query: 263 GRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVD 322
GR YPWGV EVEN EH DF LR MLI THMQDL++VT ++HYEN+RS +L +
Sbjct: 255 GRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVEN 313
Query: 323 NNKNKGQLTKSPLAQMEEERREHVAKMK-KMEMEME 357
+ NK Q+ A++ +E +A+M+ +M+M+M+
Sbjct: 314 EDMNKDQILLEKEAEL-RRMQEMIARMQAQMQMQMQ 348
>gi|56549638 septin 2 [Homo sapiens]
Length = 361
Score = 377 bits (969), Expect = e-105
Identities = 194/336 (57%), Positives = 255/336 (75%), Gaps = 9/336 (2%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPE--YPGPSHR 85
GYVGFANLPNQV+RKSVK+GFEFTLMVVGESGLGKSTLINSLFLTDLY PE PG + +
Sbjct: 16 GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLY-PERVIPGAAEK 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
I++TVQ+E S V I+E GV+L LT+VDTPG+GDA++ +C++ +I YID +FE YL+ ES
Sbjct: 75 IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDES 134
Query: 146 RVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NRR + DNRV CC YFI+P GHGLKPLD+ FMK +H KVNI+P+IAKADTLT +E ++
Sbjct: 135 GLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERER 194
Query: 206 FKKQIMKEIQEHKIKIYEFPET---DDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVR 262
KK+I+ EI+EH IKIY P+ +DE+ + + +K +P +VVGSN +IE GK+VR
Sbjct: 195 LKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVR 254
Query: 263 GRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVD 322
GR YPWGV EVEN EH DF LR MLI THMQDL++VT ++HYEN+RS +L +
Sbjct: 255 GRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVEN 313
Query: 323 NNKNKGQLTKSPLAQMEEERREHVAKMK-KMEMEME 357
+ NK Q+ A++ +E +A+M+ +M+M+M+
Sbjct: 314 EDMNKDQILLEKEAEL-RRMQEMIARMQAQMQMQMQ 348
>gi|56549636 septin 2 [Homo sapiens]
Length = 361
Score = 377 bits (969), Expect = e-105
Identities = 194/336 (57%), Positives = 255/336 (75%), Gaps = 9/336 (2%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPE--YPGPSHR 85
GYVGFANLPNQV+RKSVK+GFEFTLMVVGESGLGKSTLINSLFLTDLY PE PG + +
Sbjct: 16 GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLY-PERVIPGAAEK 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
I++TVQ+E S V I+E GV+L LT+VDTPG+GDA++ +C++ +I YID +FE YL+ ES
Sbjct: 75 IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDES 134
Query: 146 RVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NRR + DNRV CC YFI+P GHGLKPLD+ FMK +H KVNI+P+IAKADTLT +E ++
Sbjct: 135 GLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERER 194
Query: 206 FKKQIMKEIQEHKIKIYEFPET---DDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVR 262
KK+I+ EI+EH IKIY P+ +DE+ + + +K +P +VVGSN +IE GK+VR
Sbjct: 195 LKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVR 254
Query: 263 GRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVD 322
GR YPWGV EVEN EH DF LR MLI THMQDL++VT ++HYEN+RS +L +
Sbjct: 255 GRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVEN 313
Query: 323 NNKNKGQLTKSPLAQMEEERREHVAKMK-KMEMEME 357
+ NK Q+ A++ +E +A+M+ +M+M+M+
Sbjct: 314 EDMNKDQILLEKEAEL-RRMQEMIARMQAQMQMQMQ 348
>gi|4758158 septin 2 [Homo sapiens]
Length = 361
Score = 377 bits (969), Expect = e-105
Identities = 194/336 (57%), Positives = 255/336 (75%), Gaps = 9/336 (2%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPE--YPGPSHR 85
GYVGFANLPNQV+RKSVK+GFEFTLMVVGESGLGKSTLINSLFLTDLY PE PG + +
Sbjct: 16 GYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLY-PERVIPGAAEK 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
I++TVQ+E S V I+E GV+L LT+VDTPG+GDA++ +C++ +I YID +FE YL+ ES
Sbjct: 75 IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDES 134
Query: 146 RVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NRR + DNRV CC YFI+P GHGLKPLD+ FMK +H KVNI+P+IAKADTLT +E ++
Sbjct: 135 GLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERER 194
Query: 206 FKKQIMKEIQEHKIKIYEFPET---DDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVR 262
KK+I+ EI+EH IKIY P+ +DE+ + + +K +P +VVGSN +IE GK+VR
Sbjct: 195 LKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVR 254
Query: 263 GRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVD 322
GR YPWGV EVEN EH DF LR MLI THMQDL++VT ++HYEN+RS +L +
Sbjct: 255 GRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVEN 313
Query: 323 NNKNKGQLTKSPLAQMEEERREHVAKMK-KMEMEME 357
+ NK Q+ A++ +E +A+M+ +M+M+M+
Sbjct: 314 EDMNKDQILLEKEAEL-RRMQEMIARMQAQMQMQMQ 348
>gi|16604248 septin 1 [Homo sapiens]
Length = 367
Score = 349 bits (895), Expect = 3e-96
Identities = 176/363 (48%), Positives = 257/363 (70%), Gaps = 16/363 (4%)
Query: 29 YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 87
YVGFA LPNQ++RKSVK+GF+FTLMV GESGLGKSTLINSLFLT+LY + P S R+
Sbjct: 5 YVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLT 64
Query: 88 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147
+T+ +E+ V I+EGGV++ LT+VDTPGFGD+VD S+CW PV+ +I+ +FE YL ES +
Sbjct: 65 QTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGL 124
Query: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207
NR+ + D+RV CCLYFI+P G GL+PLD+ F++ +HEKVNIIP+I KAD L P+E Q K
Sbjct: 125 NRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALK 184
Query: 208 KQIMKEIQEHKIKIYEFPETDDEEENKLVK---KIKDRLPLAVVGSNTIIEVNGKR-VRG 263
++I +++E +I IY+FPE D +E+ + ++K+ +P AVVGS ++ G R VRG
Sbjct: 185 QKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRG 244
Query: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323
R+Y WG EVEN HCDF LR ML++TH+QDLK+VT+++ YE YR+R L ++ G +
Sbjct: 245 RRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARD 304
Query: 324 NKNKGQLTKS----------PLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKD 373
++ +L++ PLA E+ RE ++++M+ EM + + ++++ + +
Sbjct: 305 RASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQ-EMLEKMQAQMQQSQAQGEQ 363
Query: 374 SEA 376
S+A
Sbjct: 364 SDA 366
>gi|149363638 septin 8 isoform c [Homo sapiens]
Length = 442
Score = 327 bits (837), Expect = 2e-89
Identities = 182/432 (42%), Positives = 267/432 (61%), Gaps = 18/432 (4%)
Query: 12 ERSVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFL 71
ER N+ + +L G+VGF +LP+Q+ KSV +GF F ++ VGE+G+GKSTL+N+LF
Sbjct: 7 ERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFN 66
Query: 72 TDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVID 131
T + E SH + V++ ++E VQL LTIVD GFGD ++ ++P++D
Sbjct: 67 TTFETEE---ASHH-EACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVD 122
Query: 132 YIDSKFEDYLNAESRVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNII 189
YID++FE+YL E ++ R D R+ CLYFI P+GH LK LD+ MK+L KVNII
Sbjct: 123 YIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNII 182
Query: 190 PLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVG 249
P+IAKADT++ E +FK +IM E+ + ++IY+FP TDDE ++ + LP AVVG
Sbjct: 183 PIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFP-TDDEAVAEINAVMNAHLPFAVVG 241
Query: 250 SNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYR 309
S ++V K VR RQYPWGV +VEN HCDF LR MLIR +M+DL++ T++ HYE YR
Sbjct: 242 STEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYR 301
Query: 310 SRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQ 369
KL + + D + L ++ E +R+E ++++++ E EM Q+F KVKE
Sbjct: 302 RCKLEEMGFQDSDGDSQPFSLQET----YEAKRKEFLSELQRKEEEMRQMFVNKVKETEL 357
Query: 370 KLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDE-------KANWEAQQRILEQQNS 422
+LK+ E EL + E +K+ + + +++EEKRR+ E+E KA EA Q S
Sbjct: 358 ELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATS 417
Query: 423 SRTLEKNKKKGK 434
+ L K+K K K
Sbjct: 418 QQPLRKDKDKKK 429
>gi|149363689 septin 8 isoform a [Homo sapiens]
Length = 483
Score = 325 bits (834), Expect = 4e-89
Identities = 181/430 (42%), Positives = 266/430 (61%), Gaps = 18/430 (4%)
Query: 12 ERSVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFL 71
ER N+ + +L G+VGF +LP+Q+ KSV +GF F ++ VGE+G+GKSTL+N+LF
Sbjct: 7 ERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFN 66
Query: 72 TDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVID 131
T + E SH + V++ ++E VQL LTIVD GFGD ++ ++P++D
Sbjct: 67 TTFETEE---ASHH-EACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVD 122
Query: 132 YIDSKFEDYLNAESRVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNII 189
YID++FE+YL E ++ R D R+ CLYFI P+GH LK LD+ MK+L KVNII
Sbjct: 123 YIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNII 182
Query: 190 PLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVG 249
P+IAKADT++ E +FK +IM E+ + ++IY+FP TDDE ++ + LP AVVG
Sbjct: 183 PIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFP-TDDEAVAEINAVMNAHLPFAVVG 241
Query: 250 SNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYR 309
S ++V K VR RQYPWGV +VEN HCDF LR MLIR +M+DL++ T++ HYE YR
Sbjct: 242 STEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYR 301
Query: 310 SRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQ 369
KL + + D + L ++ E +R+E ++++++ E EM Q+F KVKE
Sbjct: 302 RCKLEEMGFQDSDGDSQPFSLQET----YEAKRKEFLSELQRKEEEMRQMFVNKVKETEL 357
Query: 370 KLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDE-------KANWEAQQRILEQQNS 422
+LK+ E EL + E +K+ + + +++EEKRR+ E+E KA EA Q S
Sbjct: 358 ELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATS 417
Query: 423 SRTLEKNKKK 432
+ L K+K K
Sbjct: 418 QQPLRKDKDK 427
>gi|149363661 septin 8 isoform b [Homo sapiens]
Length = 429
Score = 325 bits (834), Expect = 4e-89
Identities = 181/430 (42%), Positives = 266/430 (61%), Gaps = 18/430 (4%)
Query: 12 ERSVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFL 71
ER N+ + +L G+VGF +LP+Q+ KSV +GF F ++ VGE+G+GKSTL+N+LF
Sbjct: 7 ERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFN 66
Query: 72 TDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVID 131
T + E SH + V++ ++E VQL LTIVD GFGD ++ ++P++D
Sbjct: 67 TTFETEE---ASHH-EACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVD 122
Query: 132 YIDSKFEDYLNAESRVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNII 189
YID++FE+YL E ++ R D R+ CLYFI P+GH LK LD+ MK+L KVNII
Sbjct: 123 YIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNII 182
Query: 190 PLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVG 249
P+IAKADT++ E +FK +IM E+ + ++IY+FP TDDE ++ + LP AVVG
Sbjct: 183 PIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFP-TDDEAVAEINAVMNAHLPFAVVG 241
Query: 250 SNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYR 309
S ++V K VR RQYPWGV +VEN HCDF LR MLIR +M+DL++ T++ HYE YR
Sbjct: 242 STEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYR 301
Query: 310 SRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQ 369
KL + + D + L ++ E +R+E ++++++ E EM Q+F KVKE
Sbjct: 302 RCKLEEMGFQDSDGDSQPFSLQET----YEAKRKEFLSELQRKEEEMRQMFVNKVKETEL 357
Query: 370 KLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDE-------KANWEAQQRILEQQNS 422
+LK+ E EL + E +K+ + + +++EEKRR+ E+E KA EA Q S
Sbjct: 358 ELKEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATS 417
Query: 423 SRTLEKNKKK 432
+ L K+K K
Sbjct: 418 QQPLRKDKDK 427
>gi|8922712 septin 11 [Homo sapiens]
Length = 429
Score = 322 bits (825), Expect = 4e-88
Identities = 173/421 (41%), Positives = 261/421 (61%), Gaps = 18/421 (4%)
Query: 25 NLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSH 84
+L G+VGF +LP+Q+ KS +GF F ++ VGE+G+GKSTL+++LF T S P+
Sbjct: 17 SLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESD----PAT 72
Query: 85 RIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAE 144
+ V+++ ++E V+L LTIVDT GFGD ++ + ++P+++YID++FE YL E
Sbjct: 73 HNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEE 132
Query: 145 SRVNRR--QMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEE 202
++ R D R+ CLYFIAP+GH LK LD+ MK+L KVNIIP+IAKADT+ E
Sbjct: 133 LKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNE 192
Query: 203 CQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVR 262
+FK +IM E+ + ++IY+FP TD+E ++ + LP AVVGS +++ K +
Sbjct: 193 LHKFKSKIMSELVSNGVQIYQFP-TDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAK 251
Query: 263 GRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVD 322
RQYPWGV +VEN HCDF LR MLIR +M+DL++ T+ HYE YR KL + + D
Sbjct: 252 ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTD 311
Query: 323 NNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAE----- 377
+ L ++ E +R E + +++K E EM Q+F M+VKEK +LK++E E
Sbjct: 312 PDSKPFSLQET----YEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKF 367
Query: 378 --LQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKGKI 435
L+R H++ KK +E + KELEE+ F+ +KA + Q +Q + +T + KK
Sbjct: 368 DLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNAS 427
Query: 436 F 436
F
Sbjct: 428 F 428
>gi|22035581 septin 6 isoform D [Homo sapiens]
Length = 429
Score = 315 bits (806), Expect = 7e-86
Identities = 169/420 (40%), Positives = 261/420 (62%), Gaps = 18/420 (4%)
Query: 26 LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 85
L G+VGF +LP+Q+ KSV +GF F ++ VGE+GLGKSTL+++LF T P+
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE----PATH 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
+ VQ++ + ++E V+L LTIV T GFGD ++ + ++P++++ID++FE YL E
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 146 RVNR--RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 203
++ R D+R+ CLYFIAP+GH LK LD+ MK+L KVNIIP+IAKAD ++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 204 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 263
+FK +I E+ + ++IY+FP TDDE ++ + LP AV+GS +++ K +R
Sbjct: 195 TKFKIKITSELVSNGVQIYQFP-TDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRA 253
Query: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323
RQYPWG +VEN HCDF LR MLIR +M+DL++ T+ HYE YR KL + + D
Sbjct: 254 RQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDP 313
Query: 324 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 383
+ L ++ E +R E + +++K E EM Q+F +VKEK +LK++E EL + +
Sbjct: 314 DSKPFSLQET----YEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFD 369
Query: 384 QMKKNLEAQHKELEEKRRQFEDE-------KANWEAQQRILEQQNSSRTLEKNKKKGKIF 436
++KK + + K+LE+K++ +DE K E Q Q S+TL+++K+K F
Sbjct: 370 RLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKNFF 429
>gi|21361478 septin 6 isoform B [Homo sapiens]
Length = 434
Score = 313 bits (802), Expect = 2e-85
Identities = 168/416 (40%), Positives = 260/416 (62%), Gaps = 18/416 (4%)
Query: 26 LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 85
L G+VGF +LP+Q+ KSV +GF F ++ VGE+GLGKSTL+++LF T P+
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE----PATH 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
+ VQ++ + ++E V+L LTIV T GFGD ++ + ++P++++ID++FE YL E
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 146 RVNR--RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 203
++ R D+R+ CLYFIAP+GH LK LD+ MK+L KVNIIP+IAKAD ++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 204 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 263
+FK +I E+ + ++IY+FP TDDE ++ + LP AV+GS +++ K +R
Sbjct: 195 TKFKIKITSELVSNGVQIYQFP-TDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRA 253
Query: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323
RQYPWG +VEN HCDF LR MLIR +M+DL++ T+ HYE YR KL + + D
Sbjct: 254 RQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDP 313
Query: 324 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 383
+ L ++ E +R E + +++K E EM Q+F +VKEK +LK++E EL + +
Sbjct: 314 DSKPFSLQET----YEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFD 369
Query: 384 QMKKNLEAQHKELEEKRRQFEDE-------KANWEAQQRILEQQNSSRTLEKNKKK 432
++KK + + K+LE+K++ +DE K E Q Q S+TL+++K+K
Sbjct: 370 RLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEK 425
>gi|22035579 septin 6 isoform A [Homo sapiens]
Length = 427
Score = 313 bits (802), Expect = 2e-85
Identities = 168/416 (40%), Positives = 260/416 (62%), Gaps = 18/416 (4%)
Query: 26 LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 85
L G+VGF +LP+Q+ KSV +GF F ++ VGE+GLGKSTL+++LF T P+
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE----PATH 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
+ VQ++ + ++E V+L LTIV T GFGD ++ + ++P++++ID++FE YL E
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 146 RVNR--RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 203
++ R D+R+ CLYFIAP+GH LK LD+ MK+L KVNIIP+IAKAD ++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 204 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 263
+FK +I E+ + ++IY+FP TDDE ++ + LP AV+GS +++ K +R
Sbjct: 195 TKFKIKITSELVSNGVQIYQFP-TDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRA 253
Query: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323
RQYPWG +VEN HCDF LR MLIR +M+DL++ T+ HYE YR KL + + D
Sbjct: 254 RQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDP 313
Query: 324 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 383
+ L ++ E +R E + +++K E EM Q+F +VKEK +LK++E EL + +
Sbjct: 314 DSKPFSLQET----YEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFD 369
Query: 384 QMKKNLEAQHKELEEKRRQFEDE-------KANWEAQQRILEQQNSSRTLEKNKKK 432
++KK + + K+LE+K++ +DE K E Q Q S+TL+++K+K
Sbjct: 370 RLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEK 425
>gi|22035577 septin 6 isoform A [Homo sapiens]
Length = 427
Score = 313 bits (802), Expect = 2e-85
Identities = 168/416 (40%), Positives = 260/416 (62%), Gaps = 18/416 (4%)
Query: 26 LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 85
L G+VGF +LP+Q+ KSV +GF F ++ VGE+GLGKSTL+++LF T P+
Sbjct: 19 LAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE----PATH 74
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
+ VQ++ + ++E V+L LTIV T GFGD ++ + ++P++++ID++FE YL E
Sbjct: 75 TQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEEL 134
Query: 146 RVNR--RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 203
++ R D+R+ CLYFIAP+GH LK LD+ MK+L KVNIIP+IAKAD ++ E
Sbjct: 135 KIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSEL 194
Query: 204 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 263
+FK +I E+ + ++IY+FP TDDE ++ + LP AV+GS +++ K +R
Sbjct: 195 TKFKIKITSELVSNGVQIYQFP-TDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRA 253
Query: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323
RQYPWG +VEN HCDF LR MLIR +M+DL++ T+ HYE YR KL + + D
Sbjct: 254 RQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDP 313
Query: 324 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 383
+ L ++ E +R E + +++K E EM Q+F +VKEK +LK++E EL + +
Sbjct: 314 DSKPFSLQET----YEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFD 369
Query: 384 QMKKNLEAQHKELEEKRRQFEDE-------KANWEAQQRILEQQNSSRTLEKNKKK 432
++KK + + K+LE+K++ +DE K E Q Q S+TL+++K+K
Sbjct: 370 RLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEK 425
>gi|30795193 septin 10 isoform 2 [Homo sapiens]
Length = 431
Score = 309 bits (792), Expect = 3e-84
Identities = 165/383 (43%), Positives = 246/383 (64%), Gaps = 11/383 (2%)
Query: 26 LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 85
+ G+VGF +LP+Q+ +S+++GF F ++ VGE+G+GKSTLI++LF T+ E S
Sbjct: 20 MSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE----SSH 75
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
V+++ ++E VQL LTIV+T GFGD ++ +QP++DYID++FE YL E
Sbjct: 76 FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEEL 135
Query: 146 RVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 203
++ R D+R+ CLYFI+P+GH LK LD+ MK L KVNIIP+IAKADT++ E
Sbjct: 136 KIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTEL 195
Query: 204 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 263
Q+FK ++M E+ + ++IY+FP TDD+ K+ + +LP AVVGS ++V K V+
Sbjct: 196 QKFKIKLMSELVSNGVQIYQFP-TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKA 254
Query: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323
RQYPWGV +VEN HCDF LR MLI T+M+DL++ T+ HYE YR KL + + V
Sbjct: 255 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGP 314
Query: 324 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 383
+ ++ E +R E + ++ E EM+Q+F +VKEK LK++E ELQ + E
Sbjct: 315 ENKPVSVQET----YEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFE 370
Query: 384 QMKKNLEAQHKELEEKRRQFEDE 406
+K+ + + +LEEKRR E+E
Sbjct: 371 HLKRLHQEERMKLEEKRRLLEEE 393
>gi|21945064 septin 10 isoform 1 [Homo sapiens]
Length = 454
Score = 309 bits (792), Expect = 3e-84
Identities = 165/383 (43%), Positives = 246/383 (64%), Gaps = 11/383 (2%)
Query: 26 LEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHR 85
+ G+VGF +LP+Q+ +S+++GF F ++ VGE+G+GKSTLI++LF T+ E S
Sbjct: 43 MSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYE----SSH 98
Query: 86 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAES 145
V+++ ++E VQL LTIV+T GFGD ++ +QP++DYID++FE YL E
Sbjct: 99 FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEEL 158
Query: 146 RVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEEC 203
++ R D+R+ CLYFI+P+GH LK LD+ MK L KVNIIP+IAKADT++ E
Sbjct: 159 KIKRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTEL 218
Query: 204 QQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRG 263
Q+FK ++M E+ + ++IY+FP TDD+ K+ + +LP AVVGS ++V K V+
Sbjct: 219 QKFKIKLMSELVSNGVQIYQFP-TDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKA 277
Query: 264 RQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDN 323
RQYPWGV +VEN HCDF LR MLI T+M+DL++ T+ HYE YR KL + + V
Sbjct: 278 RQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGP 337
Query: 324 NKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHE 383
+ ++ E +R E + ++ E EM+Q+F +VKEK LK++E ELQ + E
Sbjct: 338 ENKPVSVQET----YEAKRHEFHGERQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFE 393
Query: 384 QMKKNLEAQHKELEEKRRQFEDE 406
+K+ + + +LEEKRR E+E
Sbjct: 394 HLKRLHQEERMKLEEKRRLLEEE 416
>gi|156602655 septin 3 isoform A [Homo sapiens]
Length = 358
Score = 308 bits (789), Expect = 6e-84
Identities = 148/304 (48%), Positives = 221/304 (72%), Gaps = 4/304 (1%)
Query: 14 SVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTD 73
+V M+ NL GY+G + Q+ +K++K GF+F +MVVG+SGLGKSTL+N+LF +
Sbjct: 26 AVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQ 85
Query: 74 LYSPEYP-GPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDY 132
+ +I KTV+++ +I+EGGV++ LT++DTPGFGD ++N NCW+P+ Y
Sbjct: 86 VSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKY 145
Query: 133 IDSKFEDYLNAESRVNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPL 191
I+ ++E +L E + R++ +PD RV CCLYFI+P+GH L+PLD+EFMK L + VNIIP+
Sbjct: 146 INEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPV 205
Query: 192 IAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVK-KIK-DRLPLAVVG 249
IAKADT+T EE +FK+++ KE++ + I+ Y E D++ E+K KI+ + +P AVVG
Sbjct: 206 IAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVG 265
Query: 250 SNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYR 309
S+ +VNGKRV GR+ PWG+ EVEN HC+F +LR+ +IRTH+QDLK+VT+N+HYE YR
Sbjct: 266 SDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYR 325
Query: 310 SRKL 313
+++L
Sbjct: 326 AKRL 329
>gi|156602653 septin 3 isoform B [Homo sapiens]
Length = 350
Score = 308 bits (789), Expect = 6e-84
Identities = 148/304 (48%), Positives = 221/304 (72%), Gaps = 4/304 (1%)
Query: 14 SVNSSTMAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTD 73
+V M+ NL GY+G + Q+ +K++K GF+F +MVVG+SGLGKSTL+N+LF +
Sbjct: 26 AVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQ 85
Query: 74 LYSPEYP-GPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDY 132
+ +I KTV+++ +I+EGGV++ LT++DTPGFGD ++N NCW+P+ Y
Sbjct: 86 VSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKY 145
Query: 133 IDSKFEDYLNAESRVNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPL 191
I+ ++E +L E + R++ +PD RV CCLYFI+P+GH L+PLD+EFMK L + VNIIP+
Sbjct: 146 INEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPV 205
Query: 192 IAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVK-KIK-DRLPLAVVG 249
IAKADT+T EE +FK+++ KE++ + I+ Y E D++ E+K KI+ + +P AVVG
Sbjct: 206 IAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVG 265
Query: 250 SNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYR 309
S+ +VNGKRV GR+ PWG+ EVEN HC+F +LR+ +IRTH+QDLK+VT+N+HYE YR
Sbjct: 266 SDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYR 325
Query: 310 SRKL 313
+++L
Sbjct: 326 AKRL 329
>gi|164698504 septin 9 isoform f [Homo sapiens]
Length = 335
Score = 306 bits (784), Expect = 2e-83
Identities = 148/304 (48%), Positives = 220/304 (72%), Gaps = 6/304 (1%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRI 86
GYVG ++ Q+ RK++K+GFEF +MVVG+SGLGKSTLIN+LF + + P RI
Sbjct: 26 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 85
Query: 87 KKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESR 146
KT++++ I+E GV++ LT++DTPGFGD ++N NCWQP++ +I+ ++E YL E
Sbjct: 86 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 145
Query: 147 VNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NR++ +PD RV CCLYFI +GH L+PLDIEFMKRL + VNI+P+IAKADTLT EE
Sbjct: 146 INRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVH 205
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLV-KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
FK++I ++ + I +Y E D++ E++LV +K ++ +P AVVGS+ +VNGKR+ GR
Sbjct: 206 FKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGR 265
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL---AAVTYNGV 321
+ WG EVEN HC+F LR++LIRTHMQ++KD+T+++H+E YR ++L ++ NG+
Sbjct: 266 KTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGM 325
Query: 322 DNNK 325
+ +
Sbjct: 326 EEKE 329
>gi|164698502 septin 9 isoform d [Homo sapiens]
Length = 474
Score = 306 bits (784), Expect = 2e-83
Identities = 148/304 (48%), Positives = 220/304 (72%), Gaps = 6/304 (1%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRI 86
GYVG ++ Q+ RK++K+GFEF +MVVG+SGLGKSTLIN+LF + + P RI
Sbjct: 165 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 224
Query: 87 KKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESR 146
KT++++ I+E GV++ LT++DTPGFGD ++N NCWQP++ +I+ ++E YL E
Sbjct: 225 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 284
Query: 147 VNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NR++ +PD RV CCLYFI +GH L+PLDIEFMKRL + VNI+P+IAKADTLT EE
Sbjct: 285 INRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVH 344
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLV-KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
FK++I ++ + I +Y E D++ E++LV +K ++ +P AVVGS+ +VNGKR+ GR
Sbjct: 345 FKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGR 404
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL---AAVTYNGV 321
+ WG EVEN HC+F LR++LIRTHMQ++KD+T+++H+E YR ++L ++ NG+
Sbjct: 405 KTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGM 464
Query: 322 DNNK 325
+ +
Sbjct: 465 EEKE 468
>gi|164698500 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 306 bits (784), Expect = 2e-83
Identities = 148/304 (48%), Positives = 220/304 (72%), Gaps = 6/304 (1%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRI 86
GYVG ++ Q+ RK++K+GFEF +MVVG+SGLGKSTLIN+LF + + P RI
Sbjct: 113 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 172
Query: 87 KKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESR 146
KT++++ I+E GV++ LT++DTPGFGD ++N NCWQP++ +I+ ++E YL E
Sbjct: 173 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 232
Query: 147 VNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NR++ +PD RV CCLYFI +GH L+PLDIEFMKRL + VNI+P+IAKADTLT EE
Sbjct: 233 INRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVH 292
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLV-KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
FK++I ++ + I +Y E D++ E++LV +K ++ +P AVVGS+ +VNGKR+ GR
Sbjct: 293 FKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGR 352
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL---AAVTYNGV 321
+ WG EVEN HC+F LR++LIRTHMQ++KD+T+++H+E YR ++L ++ NG+
Sbjct: 353 KTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGM 412
Query: 322 DNNK 325
+ +
Sbjct: 413 EEKE 416
>gi|164698498 septin 9 isoform b [Homo sapiens]
Length = 579
Score = 306 bits (784), Expect = 2e-83
Identities = 148/304 (48%), Positives = 220/304 (72%), Gaps = 6/304 (1%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRI 86
GYVG ++ Q+ RK++K+GFEF +MVVG+SGLGKSTLIN+LF + + P RI
Sbjct: 270 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 329
Query: 87 KKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESR 146
KT++++ I+E GV++ LT++DTPGFGD ++N NCWQP++ +I+ ++E YL E
Sbjct: 330 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 389
Query: 147 VNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NR++ +PD RV CCLYFI +GH L+PLDIEFMKRL + VNI+P+IAKADTLT EE
Sbjct: 390 INRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVH 449
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLV-KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
FK++I ++ + I +Y E D++ E++LV +K ++ +P AVVGS+ +VNGKR+ GR
Sbjct: 450 FKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGR 509
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL---AAVTYNGV 321
+ WG EVEN HC+F LR++LIRTHMQ++KD+T+++H+E YR ++L ++ NG+
Sbjct: 510 KTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGM 569
Query: 322 DNNK 325
+ +
Sbjct: 570 EEKE 573
>gi|164698496 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 306 bits (784), Expect = 2e-83
Identities = 148/304 (48%), Positives = 220/304 (72%), Gaps = 6/304 (1%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRI 86
GYVG ++ Q+ RK++K+GFEF +MVVG+SGLGKSTLIN+LF + + P RI
Sbjct: 113 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 172
Query: 87 KKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESR 146
KT++++ I+E GV++ LT++DTPGFGD ++N NCWQP++ +I+ ++E YL E
Sbjct: 173 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 232
Query: 147 VNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NR++ +PD RV CCLYFI +GH L+PLDIEFMKRL + VNI+P+IAKADTLT EE
Sbjct: 233 INRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVH 292
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLV-KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
FK++I ++ + I +Y E D++ E++LV +K ++ +P AVVGS+ +VNGKR+ GR
Sbjct: 293 FKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGR 352
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL---AAVTYNGV 321
+ WG EVEN HC+F LR++LIRTHMQ++KD+T+++H+E YR ++L ++ NG+
Sbjct: 353 KTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGM 412
Query: 322 DNNK 325
+ +
Sbjct: 413 EEKE 416
>gi|164698494 septin 9 isoform a [Homo sapiens]
Length = 586
Score = 306 bits (784), Expect = 2e-83
Identities = 148/304 (48%), Positives = 220/304 (72%), Gaps = 6/304 (1%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRI 86
GYVG ++ Q+ RK++K+GFEF +MVVG+SGLGKSTLIN+LF + + P RI
Sbjct: 277 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 336
Query: 87 KKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESR 146
KT++++ I+E GV++ LT++DTPGFGD ++N NCWQP++ +I+ ++E YL E
Sbjct: 337 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 396
Query: 147 VNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NR++ +PD RV CCLYFI +GH L+PLDIEFMKRL + VNI+P+IAKADTLT EE
Sbjct: 397 INRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVH 456
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLV-KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
FK++I ++ + I +Y E D++ E++LV +K ++ +P AVVGS+ +VNGKR+ GR
Sbjct: 457 FKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGR 516
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL---AAVTYNGV 321
+ WG EVEN HC+F LR++LIRTHMQ++KD+T+++H+E YR ++L ++ NG+
Sbjct: 517 KTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGM 576
Query: 322 DNNK 325
+ +
Sbjct: 577 EEKE 580
>gi|116256489 septin 9 isoform c [Homo sapiens]
Length = 568
Score = 306 bits (784), Expect = 2e-83
Identities = 148/304 (48%), Positives = 220/304 (72%), Gaps = 6/304 (1%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRI 86
GYVG ++ Q+ RK++K+GFEF +MVVG+SGLGKSTLIN+LF + + P RI
Sbjct: 259 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERI 318
Query: 87 KKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESR 146
KT++++ I+E GV++ LT++DTPGFGD ++N NCWQP++ +I+ ++E YL E
Sbjct: 319 PKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVN 378
Query: 147 VNRRQ-MPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
+NR++ +PD RV CCLYFI +GH L+PLDIEFMKRL + VNI+P+IAKADTLT EE
Sbjct: 379 INRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVH 438
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLV-KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
FK++I ++ + I +Y E D++ E++LV +K ++ +P AVVGS+ +VNGKR+ GR
Sbjct: 439 FKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGR 498
Query: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKL---AAVTYNGV 321
+ WG EVEN HC+F LR++LIRTHMQ++KD+T+++H+E YR ++L ++ NG+
Sbjct: 499 KTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGM 558
Query: 322 DNNK 325
+ +
Sbjct: 559 EEKE 562
>gi|153252198 septin 14 [Homo sapiens]
Length = 432
Score = 305 bits (780), Expect = 7e-83
Identities = 169/411 (41%), Positives = 256/411 (62%), Gaps = 15/411 (3%)
Query: 28 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHRIK 87
G+ GF LPNQ+ +S+++GF F ++ VGE+G+GKSTLI++LF T+L + S
Sbjct: 31 GHFGFECLPNQLVSRSIRQGFTFNILCVGETGIGKSTLIDTLFNTNLKDNK----SSHFY 86
Query: 88 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147
V ++ ++E VQL LT+V+T G+GD +D +QP++DYID++FE YL E ++
Sbjct: 87 SNVGLQIQTYELQESNVQLKLTVVETVGYGDQIDKEASYQPIVDYIDAQFEAYLQEELKI 146
Query: 148 NRR--QMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQ 205
R + D+RV CLYFI+P+GH LK LD+ MK L KVNIIPLIAKADT++ + Q
Sbjct: 147 KRSLFEYHDSRVHVCLYFISPTGHSLKSLDLLTMKNLDSKVNIIPLIAKADTISKNDLQT 206
Query: 206 FKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQ 265
FK +IM E+ + I+IY+ P TD+E + + LP AVVGS ++V + VRGR
Sbjct: 207 FKNKIMSELISNGIQIYQLP-TDEETAAQANSSVSGLLPFAVVGSTDEVKVGKRMVRGRH 265
Query: 266 YPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNK 325
YPWGV +VEN HCDF LR+ML+ T+M++LK+ T+ HYE YR +KL + + V N
Sbjct: 266 YPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNN 325
Query: 326 NKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQM 385
+ E +R+E + ++ E E++Q F +VKEK K++E ELQ + E +
Sbjct: 326 QPVSFQEI----FEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHL 381
Query: 386 KKNLEAQHKELEEKRRQFEDEKANW---EAQQRILEQQNSSRT-LEKNKKK 432
K + + ++LEE+++Q E E ++ +A L+ Q S+ T +K++KK
Sbjct: 382 KMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTDTKKDKHRKK 432
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,638,472
Number of Sequences: 37866
Number of extensions: 714608
Number of successful extensions: 10464
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 435
Number of HSP's successfully gapped in prelim test: 715
Number of HSP's that attempted gapping in prelim test: 4720
Number of HSP's gapped (non-prelim): 4711
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.