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Search of human proteins with 148276979
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148276979 mitochondrial carrier triple repeat 2 [Homo
sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148276979 mitochondrial carrier triple repeat 2 [Homo sapiens] 608 e-174
gi|15529972 mitochondrial carrier triple repeat 1 [Homo sapiens] 583 e-167
gi|153792375 mitochondrial carrier triple repeat 6 [Homo sapiens] 157 1e-38
gi|11225256 uncoupling protein 1 [Homo sapiens] 61 1e-09
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 60 2e-09
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 57 3e-08
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 57 3e-08
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 56 3e-08
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 56 3e-08
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 56 3e-08
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 55 7e-08
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 54 2e-07
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 52 6e-07
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 52 8e-07
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 52 8e-07
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 52 8e-07
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 48 9e-06
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 48 9e-06
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 48 9e-06
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 48 9e-06
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 48 9e-06
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 48 9e-06
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 48 9e-06
gi|13259541 uncoupling protein 2 [Homo sapiens] 47 2e-05
gi|41462412 solute carrier family 25, member 35 [Homo sapiens] 47 2e-05
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 47 3e-05
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 47 3e-05
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 46 3e-05
gi|5453918 solute carrier family 25 (mitochondrial carrier; pero... 46 3e-05
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 45 6e-05
>gi|148276979 mitochondrial carrier triple repeat 2 [Homo sapiens]
Length = 297
Score = 608 bits (1568), Expect = e-174
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MIDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQL 60
MIDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQL
Sbjct: 1 MIDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQL 60
Query: 61 YGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFAT 120
YGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFAT
Sbjct: 61 YGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFAT 120
Query: 121 HGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
HGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL
Sbjct: 121 HGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ 240
FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ
Sbjct: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ 240
Query: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI 297
SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI
Sbjct: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI 297
>gi|15529972 mitochondrial carrier triple repeat 1 [Homo sapiens]
Length = 297
Score = 583 bits (1502), Expect = e-167
Identities = 285/297 (95%), Positives = 290/297 (97%)
Query: 1 MIDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQL 60
M+DSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAIT+PIQKVLFRQQL
Sbjct: 1 MMDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQL 60
Query: 61 YGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFAT 120
YGIKTRDA+LQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL KHV APEFAT
Sbjct: 61 YGIKTRDAILQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFAT 120
Query: 121 HGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
GVAAVLAGT EAIFTPLERVQTLLQ+HKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL
Sbjct: 121 SGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPIL 180
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ 240
FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFI GGLLGAMLGFL FPINVVKTR+Q
Sbjct: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQ 240
Query: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI 297
SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLK I
Sbjct: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKVI 297
>gi|153792375 mitochondrial carrier triple repeat 6 [Homo sapiens]
Length = 307
Score = 157 bits (397), Expect = 1e-38
Identities = 92/269 (34%), Positives = 146/269 (54%), Gaps = 14/269 (5%)
Query: 34 YLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTT 93
Y G + F + +T+PI KV+FRQQ++ + +AV QL +G + YRGI PPL+ KT
Sbjct: 31 YALGAVSNFMSTFLTFPIYKVVFRQQIHAMAVSEAVRQLWHEGPQYFYRGIYPPLLSKTL 90
Query: 94 TLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTAEAI-FTPLERVQTLLQNHKHHD 152
L+FG Y+ L C L V A +++G EA+ +P ERVQ +LQ+ +
Sbjct: 91 QGTLLFGTYDSLLCFL-SPVGPHTLGHRWAAGLMSGVVEAVALSPFERVQNVLQDGRKQA 149
Query: 153 KFTNTYQAFKALKCHGIG-----EYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTH 207
+F +T+ K +G+ YYRG P+L RN L + L+F + PI++ L A
Sbjct: 150 RFPSTFSILKEFNSYGLWGRLSLGYYRGFWPVLARNSLGSALYFSFKDPIQDGL--AEQG 207
Query: 208 SAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEFQSFPKVF---QKIWLERDRK 264
H V + G + G + + +P+ V+ +QS IG +Q+ P ++ Q +W R RK
Sbjct: 208 LPHWVPALVSGSVNGTITCLVLYPLIVLVANMQSHIG--WQNMPSLWASAQDVWNTRGRK 265
Query: 265 LINLFRGAHLNYHRSLISWGIINATYEFL 293
L+ ++RG L RS ++WG+ A ++FL
Sbjct: 266 LLLIYRGGSLVILRSSVTWGLTTAIHDFL 294
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 60.8 bits (146), Expect = 1e-09
Identities = 68/275 (24%), Positives = 119/275 (43%), Gaps = 30/275 (10%)
Query: 34 YLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVLQ-----------LRRDGFRNLYR 82
+ G A +V IT+P+ R Q+ G +V++ ++ +G LY
Sbjct: 18 FSAGIAACLADV-ITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYS 76
Query: 83 GILPPLMQKTTTLALMFGLYEDLSCLLRKHVR-APEFATHGVAAVLAG-TAEAIFTPLER 140
G+ L ++ ++ +L GLY+ + L AP + +A + G A I P E
Sbjct: 77 GLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEV 136
Query: 141 VQTLLQNHKH----HDKFTNTYQAFKALKC-HGIGEYYRGLVPILFRNGLSN----VLFF 191
V+ LQ H ++T TY A++ + G+ ++G P L R+ + N V +
Sbjct: 137 VKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYD 196
Query: 192 GLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEFQSFP 251
++ ++ A HLV+ I G AM P++VVKTR + G+++S P
Sbjct: 197 LMKEAFVKNNILADDVPCHLVSALIAGFCATAMSS----PVDVVKTRFINSPPGQYKSVP 252
Query: 252 KVFQKIWLERDRKLINLFRGAHLNYHRSLISWGII 286
K++ F+G ++ R L SW +I
Sbjct: 253 NCAMKVFTNEGPTA--FFKGLVPSFLR-LGSWNVI 284
Score = 42.4 bits (98), Expect = 5e-04
Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 12/169 (7%)
Query: 45 VAITYPIQKVLFRQQ----LYGIKTRDAV------LQLRRDGFRNLYRGILPPLMQKTTT 94
V I P + V R Q L+GIK R + +G L++G P LM+
Sbjct: 128 VFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVII 187
Query: 95 LALMFGLYEDLS-CLLRKHVRAPEFATHGVAAVLAG-TAEAIFTPLERVQTLLQNHKHHD 152
Y+ + ++ ++ A + H V+A++AG A A+ +P++ V+T N
Sbjct: 188 NCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSPPGQ 247
Query: 153 KFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHL 201
+ A K G +++GLVP R G NV+ F +K L
Sbjct: 248 YKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKREL 296
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 60.5 bits (145), Expect = 2e-09
Identities = 60/233 (25%), Positives = 103/233 (44%), Gaps = 16/233 (6%)
Query: 23 PHITNVGEM-KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVLQLRRDGFRNL- 80
P ++ V E + + G A + + +P+ V R Q+ T + D FR +
Sbjct: 5 PEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIF 64
Query: 81 --------YRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTAE 132
Y+GILPP++ +T A+ F +E LL +V T +A + +G E
Sbjct: 65 QMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLL-GYVSLSPALTFAIAGLGSGLTE 123
Query: 133 AI-FTPLERVQTLLQNHKH--HDKFTNTYQAFKALKCHGIG--EYYRGLVPILFRNGLSN 187
AI P E V+ LQ +++ ++ + A + +K G G +GL L R+G+ N
Sbjct: 124 AIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFN 183
Query: 188 VLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ 240
+++FG +K +P F G L G + + P +V K+R+Q
Sbjct: 184 MVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQ 236
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 56.6 bits (135), Expect = 3e-08
Identities = 66/276 (23%), Positives = 126/276 (45%), Gaps = 21/276 (7%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+ L G A + T P+ ++ Q++G K+ + ++ G R+L+RG
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 255
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAG-TAEAIFTPLERVQTL 144
+++ A+ F YE LL + + ++ +AG TA+ P+E ++T
Sbjct: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 315
Query: 145 LQNHKHHDKFTNTYQ-AFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKE 199
L K +++ Y A K LK G+G +Y+G VP I+ G+ ++ L+ +
Sbjct: 316 LAVGK-TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLD 374
Query: 200 HLPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQ 255
+ + + +V +G G L + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 375 NFAKDSVNPGVMV--LLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFR 432
Query: 256 KIWLERDRKLINLFRGAHLNYHRSLISWGIINATYE 291
+I + + L+RG N+ + L + GI YE
Sbjct: 433 RIISKEG--IPGLYRGITPNFMKVLPAVGISYVVYE 466
Score = 37.7 bits (86), Expect = 0.012
Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 7/176 (3%)
Query: 122 GVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKAL-KCHGIGEYYRGLVPIL 180
G+A ++ T+ A PL+R++ ++Q H N + F+ + K GI +RG +
Sbjct: 202 GIAGAVSRTSTA---PLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 258
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ 240
+ + F K+ L T FI G + GA +P+ V+KTRL
Sbjct: 259 IKIAPETAVKFWAYEQYKKLL-TEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLA 317
Query: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKF 296
G++ +KI + L ++G N + GI A YE L +
Sbjct: 318 VGKTGQYSGIYDCAKKIL--KHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSY 371
Score = 31.6 bits (70), Expect = 0.88
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Query: 27 NVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQ----LYGIKTRDAVLQLRR----DGFR 78
N G M CG ++ +YP+ V R Q L G + V RR +G
Sbjct: 382 NPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIP 441
Query: 79 NLYRGILPPLMQKTTTLALMFGLYEDL 105
LYRGI P M+ + + + +YE++
Sbjct: 442 GLYRGITPNFMKVLPAVGISYVVYENM 468
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 56.6 bits (135), Expect = 3e-08
Identities = 66/276 (23%), Positives = 126/276 (45%), Gaps = 21/276 (7%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+ L G A + T P+ ++ Q++G K+ + ++ G R+L+RG
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 236
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAG-TAEAIFTPLERVQTL 144
+++ A+ F YE LL + + ++ +AG TA+ P+E ++T
Sbjct: 237 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 296
Query: 145 LQNHKHHDKFTNTYQ-AFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKE 199
L K +++ Y A K LK G+G +Y+G VP I+ G+ ++ L+ +
Sbjct: 297 LAVGK-TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLD 355
Query: 200 HLPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQ 255
+ + + +V +G G L + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 356 NFAKDSVNPGVMV--LLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFR 413
Query: 256 KIWLERDRKLINLFRGAHLNYHRSLISWGIINATYE 291
+I + + L+RG N+ + L + GI YE
Sbjct: 414 RIISKEG--IPGLYRGITPNFMKVLPAVGISYVVYE 447
Score = 37.7 bits (86), Expect = 0.012
Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 7/176 (3%)
Query: 122 GVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKAL-KCHGIGEYYRGLVPIL 180
G+A ++ T+ A PL+R++ ++Q H N + F+ + K GI +RG +
Sbjct: 183 GIAGAVSRTSTA---PLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 239
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQ 240
+ + F K+ L T FI G + GA +P+ V+KTRL
Sbjct: 240 IKIAPETAVKFWAYEQYKKLL-TEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLA 298
Query: 241 SQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKF 296
G++ +KI + L ++G N + GI A YE L +
Sbjct: 299 VGKTGQYSGIYDCAKKIL--KHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSY 352
Score = 31.6 bits (70), Expect = 0.88
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Query: 27 NVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQ----LYGIKTRDAVLQLRR----DGFR 78
N G M CG ++ +YP+ V R Q L G + V RR +G
Sbjct: 363 NPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIP 422
Query: 79 NLYRGILPPLMQKTTTLALMFGLYEDL 105
LYRGI P M+ + + + +YE++
Sbjct: 423 GLYRGITPNFMKVLPAVGISYVVYENM 449
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 56.2 bits (134), Expect = 3e-08
Identities = 67/298 (22%), Positives = 112/298 (37%), Gaps = 37/298 (12%)
Query: 26 TNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQ------------LYGIKTRDAVLQLR 73
T+ H G A ++ YP+ V R Q +YG + +R
Sbjct: 41 TSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKI----MR 96
Query: 74 RDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRK--HVRAPEFATHGVAAVLAGTA 131
+GF RG+ +M A+ F YE++ L H + +G+A +A
Sbjct: 97 TEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLL 156
Query: 132 -EAIFTPLERVQTLLQ--NHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNV 188
+A+ P E V+ LQ N +H + ++ G+G +YR L N
Sbjct: 157 HDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRT---EGLGAFYRSYTTQLTMNIPFQS 213
Query: 189 LFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQ------ 242
+ F ++E + T++ + I GGL GA+ P++V KT L +Q
Sbjct: 214 IHFITYEFLQEQVNPHRTYNPQ--SHIISGGLAGALAAAATTPLDVCKTLLNTQENVALS 271
Query: 243 ---IGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI 297
I G F+ ++ + L F+G + S I + YEF F+
Sbjct: 272 LANISGRLSGMANAFRTVY--QLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 56.2 bits (134), Expect = 3e-08
Identities = 46/182 (25%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 65 TRDAVLQL-RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGV 123
T DA ++ R +G ++L+ G+ P L+ + F Y+ LS LLR + E V
Sbjct: 87 TLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIV 146
Query: 124 AAVLAGT-AEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFR 182
A ++A A + +PLE ++T +Q+ K + + + K + G +RG P + R
Sbjct: 147 AGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSE-DGWISLWRGWAPTVLR 205
Query: 183 NGLSNVLFFGLRGPIKEHL-PTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQS 241
+ + +++ +K+ L + + + +F G L G+ P +VVKT+ Q+
Sbjct: 206 DVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQT 265
Query: 242 QI 243
Q+
Sbjct: 266 QL 267
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 56.2 bits (134), Expect = 3e-08
Identities = 72/293 (24%), Positives = 116/293 (39%), Gaps = 40/293 (13%)
Query: 35 LCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVLQLR----RDGFRNLYRGILPPLMQ 90
+ GCCA KVL + + K LR ++GF LY+G +++
Sbjct: 45 IAGCCA--KTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMIR 102
Query: 91 KTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTAEAIFT-PLERVQTLLQNH- 148
A+ F +E L+ + +A +AG I T PL+ V+ L
Sbjct: 103 IFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQV 162
Query: 149 KHHDKFTNTYQAFKAL--KCHGIGEYYRGLVPILFRN----GLSNVLFFGLRGPIKEHLP 202
K +T AFK + K G +YRGL+P + G+S F L+ H P
Sbjct: 163 KGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAP 222
Query: 203 TATTHSA-----------HLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEFQSFP 251
T + H+ + + GG+ GA+ + +P +V + R+Q +G F
Sbjct: 223 TLLGRPSSDNPNVLVLKTHV--NLLCGGVAGAIAQTISYPFDVTRRRMQ--LGTVLPEFE 278
Query: 252 KVFQKIWLERDRKLI--------NLFRGAHLNYHRSLISWGIINATYEFLLKF 296
K + + K + L+RG LNY R + S + TYE + +F
Sbjct: 279 KC---LTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQF 328
Score = 49.3 bits (116), Expect = 4e-06
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 5/130 (3%)
Query: 118 FATHGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKAL-KCHGIGEYYRGL 176
F G+A A T A PL+RV+ LLQ H HH K + A +A+ + G Y+G
Sbjct: 40 FLAGGIAGCCAKTTVA---PLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGN 96
Query: 177 VPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVK 236
++ R + F K + T S H V+ + G + G +P+++V+
Sbjct: 97 GAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGH-VHRLMAGSMAGMTAVICTYPLDMVR 155
Query: 237 TRLQSQIGGE 246
RL Q+ GE
Sbjct: 156 VRLAFQVKGE 165
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 55.1 bits (131), Expect = 7e-08
Identities = 62/240 (25%), Positives = 112/240 (46%), Gaps = 22/240 (9%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAG-T 130
L ++G R+L+RG+ P L+ + A+ F Y + L H ++A +AG T
Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFT 131
Query: 131 AEAIFTPLERVQTLLQNHKHH--DKFTNTYQAF-KALKCHGIGEYYRGLVPILFRNGLSN 187
A P+ ++T LQ + ++ ++ K + G+ +YRG+ +
Sbjct: 132 AITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM-SASYAGISET 190
Query: 188 VLFFGLRGPIKEHL---PTATT-----HSAHLVNDFIGGGLLGAM----LGFLCFPINVV 235
V+ F + IK+ L TA+T S +DF+G L A + +P VV
Sbjct: 191 VIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVV 250
Query: 236 KTRLQSQIGGEFQSFPKVFQKI-WLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLL 294
+TRL+ + G +++SF FQ + L ++ +L+RG + R + + I+ ATYE ++
Sbjct: 251 RTRLREE-GTKYRSF---FQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVV 306
Score = 31.6 bits (70), Expect = 0.88
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
Query: 47 ITYPIQKVLFRQQLYGIKTRDAV----LQLRRDGFRNLYRGILPPLMQKTTTLALMFGLY 102
I YP + V R + G K R L ++ +G+ +LYRG+ L+++ A+M Y
Sbjct: 243 IAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 302
Query: 103 EDLSCLL 109
E + LL
Sbjct: 303 ELVVYLL 309
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 53.9 bits (128), Expect = 2e-07
Identities = 62/239 (25%), Positives = 105/239 (43%), Gaps = 20/239 (8%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVR-APEFATHGVAAVLAGT 130
L R+G LYRG+ P++ T A+ F + L +KH + A +L+G
Sbjct: 63 LFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGV 122
Query: 131 -AEAIFTPLERVQTLL--QNHKHHDKFTNTYQAFKAL-KCHGIGEYYRGLVPILFRNGLS 186
I TP ER++ LL Q K+T T K L + GI Y+G V L R+ +
Sbjct: 123 FTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPA 182
Query: 187 NVLFFGLRGPIKEHLPTATTHSAHLVND------FIGGGLLGAMLGFLCFPINVVKTRLQ 240
+ ++F E L T V++ + GG+ G + P +V+K+R Q
Sbjct: 183 SGMYF----MTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQ 238
Query: 241 SQIGGEFQSFPKVFQKIWLE--RDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI 297
+ G+ +P F+ + E RD + +L++G + R+ + +E +KF+
Sbjct: 239 TAPPGK---YPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 52.0 bits (123), Expect = 6e-07
Identities = 62/239 (25%), Positives = 111/239 (46%), Gaps = 21/239 (8%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAG-T 130
L ++G R+L+RG+ P L+ + A+ F Y + L H ++A +AG T
Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFT 131
Query: 131 AEAIFTPLERVQTLLQNHKHH--DKFTNTYQAF-KALKCHGIGEYYRGLVPILFRNGLSN 187
A P+ ++T LQ + ++ ++ K + G+ +YRG+ +
Sbjct: 132 AITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM-SASYAGISET 190
Query: 188 VLFFGLRGPIKEHL---PTATT-----HSAHLVNDFIGGGLLGAMLGFLCFPI---NVVK 236
V+ F + IK+ L TA+T S +DF+G L A I +VV+
Sbjct: 191 VIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHVVR 250
Query: 237 TRLQSQIGGEFQSFPKVFQKI-WLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLL 294
TRL+ + G +++SF FQ + L ++ +L+RG + R + + I+ ATYE ++
Sbjct: 251 TRLREE-GTKYRSF---FQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVV 305
Score = 28.1 bits (61), Expect = 9.7
Identities = 13/40 (32%), Positives = 24/40 (60%)
Query: 70 LQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLL 109
L ++ +G+ +LYRG+ L+++ A+M YE + LL
Sbjct: 269 LLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 308
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 51.6 bits (122), Expect = 8e-07
Identities = 59/229 (25%), Positives = 92/229 (40%), Gaps = 8/229 (3%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTA 131
LR +GF LYRG++P L+ A+ + + + + + +A AG +
Sbjct: 380 LRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGS 439
Query: 132 EAIFT-PLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLF 190
+ IFT PLE V+ LQ A L+ GI Y+G R+ + ++
Sbjct: 440 QVIFTNPLEIVKIRLQVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDIPFSAIY 498
Query: 191 FGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEFQSF 250
F + K L H L N G + G L P +V+KTRLQ ++
Sbjct: 499 FPVYAHCKLLLADENGHVGGL-NLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTY 557
Query: 251 PKV---FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKF 296
V F+KI E ++G RS +G+ TYE L ++
Sbjct: 558 SGVIDCFRKILREEGPSA--FWKGTAARVFRSSPQFGVTLVTYELLQRW 604
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 14/173 (8%)
Query: 115 APEFATHGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDK------FTNTYQAFK-ALKCH 167
A F VA + TA P++ V+T +QN + + N++ FK L+
Sbjct: 327 AYRFTLGSVAGAVGATA---VYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYE 383
Query: 168 GIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGF 227
G YRGL+P L + + +++ T S L + + GG G
Sbjct: 384 GFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKF-TRRDGSVPLPAEVLAGGCAGGSQVI 442
Query: 228 LCFPINVVKTRLQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSL 280
P+ +VK RL Q+ GE + P+V + + RD + L++GA + R +
Sbjct: 443 FTNPLEIVKIRL--QVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDI 492
Score = 38.1 bits (87), Expect = 0.009
Identities = 42/159 (26%), Positives = 67/159 (42%), Gaps = 12/159 (7%)
Query: 35 LCGCCAAFNNVAITYPIQKVLFRQQLYGIKT---RDAVLQLRRD-GFRNLYRGILPPLMQ 90
L G CA + V T P++ V R Q+ G T R + L + RD G LY+G ++
Sbjct: 431 LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLR 490
Query: 91 KTTTLALMFGLYEDLSCLL---RKHVRAPEFATHGVAAVLAGTAEAIFTPLERVQTLLQ- 146
A+ F +Y LL HV G A+ A ++ TP + ++T LQ
Sbjct: 491 DIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAG--AMAGVPAASLVTPADVIKTRLQV 548
Query: 147 -NHKHHDKFTNTYQAF-KALKCHGIGEYYRGLVPILFRN 183
++ F K L+ G +++G +FR+
Sbjct: 549 AARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRS 587
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 51.6 bits (122), Expect = 8e-07
Identities = 60/232 (25%), Positives = 96/232 (41%), Gaps = 14/232 (6%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTA 131
LR +GF LYRG+LP L+ A+ + + + + A +A AG +
Sbjct: 382 LRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGS 441
Query: 132 EAIFT-PLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLF 190
+ IFT PLE V+ LQ A ++ G Y+G R+ + ++
Sbjct: 442 QVIFTNPLEIVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIY 500
Query: 191 FGLRGPIKEHLPTATTHSAHLVND---FIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEF 247
F P H+ + + V+ + G + G L P +V+KTRLQ
Sbjct: 501 F----PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQ 556
Query: 248 QSFPKV---FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKF 296
++ V F+KI E K L++GA RS +G+ TYE L ++
Sbjct: 557 TTYSGVIDCFRKILREEGPKA--LWKGAGARVFRSSPQFGVTLLTYELLQRW 606
Score = 47.0 bits (110), Expect = 2e-05
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 14/180 (7%)
Query: 108 LLRKHVRAPEFATHGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFT------NTYQAF 161
LL+ A F VA + TA P++ V+T +QN + F N++ F
Sbjct: 322 LLQVAESAYRFGLGSVAGAVGATA---VYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCF 378
Query: 162 -KALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGL 220
K L+ G YRGL+P L + + +++ S L + + GG
Sbjct: 379 KKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF-MHKDGSVPLAAEILAGGC 437
Query: 221 LGAMLGFLCFPINVVKTRLQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSL 280
G P+ +VK RL Q+ GE + P+V + + RD +++GA + R +
Sbjct: 438 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDI 494
Score = 35.0 bits (79), Expect = 0.079
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 5/117 (4%)
Query: 35 LCGCCAAFNNVAITYPIQKVLFRQQLYGIKT---RDAVLQLRRD-GFRNLYRGILPPLMQ 90
L G CA + V T P++ V R Q+ G T R + L + RD GF +Y+G ++
Sbjct: 433 LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLR 492
Query: 91 KTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAG-TAEAIFTPLERVQTLLQ 146
A+ F Y + + +A +AG A ++ TP + ++T LQ
Sbjct: 493 DIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ 549
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 51.6 bits (122), Expect = 8e-07
Identities = 60/232 (25%), Positives = 96/232 (41%), Gaps = 14/232 (6%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTA 131
LR +GF LYRG+LP L+ A+ + + + + A +A AG +
Sbjct: 383 LRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGS 442
Query: 132 EAIFT-PLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLF 190
+ IFT PLE V+ LQ A ++ G Y+G R+ + ++
Sbjct: 443 QVIFTNPLEIVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIY 501
Query: 191 FGLRGPIKEHLPTATTHSAHLVND---FIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEF 247
F P H+ + + V+ + G + G L P +V+KTRLQ
Sbjct: 502 F----PCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQ 557
Query: 248 QSFPKV---FQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKF 296
++ V F+KI E K L++GA RS +G+ TYE L ++
Sbjct: 558 TTYSGVIDCFRKILREEGPKA--LWKGAGARVFRSSPQFGVTLLTYELLQRW 607
Score = 47.0 bits (110), Expect = 2e-05
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 14/180 (7%)
Query: 108 LLRKHVRAPEFATHGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFT------NTYQAF 161
LL+ A F VA + TA P++ V+T +QN + F N++ F
Sbjct: 323 LLQVAESAYRFGLGSVAGAVGATA---VYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCF 379
Query: 162 -KALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGL 220
K L+ G YRGL+P L + + +++ S L + + GG
Sbjct: 380 KKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF-MHKDGSVPLAAEILAGGC 438
Query: 221 LGAMLGFLCFPINVVKTRLQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSL 280
G P+ +VK RL Q+ GE + P+V + + RD +++GA + R +
Sbjct: 439 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDI 495
Score = 35.0 bits (79), Expect = 0.079
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 5/117 (4%)
Query: 35 LCGCCAAFNNVAITYPIQKVLFRQQLYGIKT---RDAVLQLRRD-GFRNLYRGILPPLMQ 90
L G CA + V T P++ V R Q+ G T R + L + RD GF +Y+G ++
Sbjct: 434 LAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLR 493
Query: 91 KTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAG-TAEAIFTPLERVQTLLQ 146
A+ F Y + + +A +AG A ++ TP + ++T LQ
Sbjct: 494 DIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ 550
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 48.1 bits (113), Expect = 9e-06
Identities = 60/277 (21%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGT-AEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG A++ P+E ++T
Sbjct: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
Query: 145 LQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKEH 200
+ K A + L G+ +Y+G VP I+ G+ ++ L+ +H
Sbjct: 308 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 367
Query: 201 LPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQK 256
+ V + G + + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 368 YAVNSADPGVFV--LLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 425
Query: 257 IWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
I R L+RG N+ + + + I YE L
Sbjct: 426 IL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 460
Score = 29.6 bits (65), Expect = 3.3
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 36 CGCCAAFNNVAITYPIQKVLFRQQLYGI------KTRDAVLQ--LRRDGFRNLYRGILPP 87
CG ++ +YP+ V R Q T ++ + LR +G LYRG+ P
Sbjct: 383 CGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPN 442
Query: 88 LMQKTTTLALMFGLYEDLSCLL 109
M+ +++ + +YE+L L
Sbjct: 443 FMKVIPAVSISYVVYENLKITL 464
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 48.1 bits (113), Expect = 9e-06
Identities = 60/277 (21%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 281
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGT-AEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG A++ P+E ++T
Sbjct: 282 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 341
Query: 145 LQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKEH 200
+ K A + L G+ +Y+G VP I+ G+ ++ L+ +H
Sbjct: 342 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 401
Query: 201 LPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQK 256
+ V + G + + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 402 YAVNSADPGVFV--LLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 459
Query: 257 IWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
I R L+RG N+ + + + I YE L
Sbjct: 460 IL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 494
Score = 29.6 bits (65), Expect = 3.3
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 36 CGCCAAFNNVAITYPIQKVLFRQQLYGI------KTRDAVLQ--LRRDGFRNLYRGILPP 87
CG ++ +YP+ V R Q T ++ + LR +G LYRG+ P
Sbjct: 417 CGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPN 476
Query: 88 LMQKTTTLALMFGLYEDLSCLL 109
M+ +++ + +YE+L L
Sbjct: 477 FMKVIPAVSISYVVYENLKITL 498
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 48.1 bits (113), Expect = 9e-06
Identities = 60/277 (21%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 267
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGT-AEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG A++ P+E ++T
Sbjct: 268 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 327
Query: 145 LQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKEH 200
+ K A + L G+ +Y+G VP I+ G+ ++ L+ +H
Sbjct: 328 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 387
Query: 201 LPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQK 256
+ V + G + + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 388 YAVNSADPGVFV--LLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 445
Query: 257 IWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
I R L+RG N+ + + + I YE L
Sbjct: 446 IL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 480
Score = 29.6 bits (65), Expect = 3.3
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 36 CGCCAAFNNVAITYPIQKVLFRQQLYGI------KTRDAVLQ--LRRDGFRNLYRGILPP 87
CG ++ +YP+ V R Q T ++ + LR +G LYRG+ P
Sbjct: 403 CGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPN 462
Query: 88 LMQKTTTLALMFGLYEDLSCLL 109
M+ +++ + +YE+L L
Sbjct: 463 FMKVIPAVSISYVVYENLKITL 484
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 48.1 bits (113), Expect = 9e-06
Identities = 60/277 (21%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGT-AEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG A++ P+E ++T
Sbjct: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
Query: 145 LQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKEH 200
+ K A + L G+ +Y+G VP I+ G+ ++ L+ +H
Sbjct: 308 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 367
Query: 201 LPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQK 256
+ V + G + + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 368 YAVNSADPGVFV--LLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 425
Query: 257 IWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
I R L+RG N+ + + + I YE L
Sbjct: 426 IL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 460
Score = 29.6 bits (65), Expect = 3.3
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 36 CGCCAAFNNVAITYPIQKVLFRQQLYGI------KTRDAVLQ--LRRDGFRNLYRGILPP 87
CG ++ +YP+ V R Q T ++ + LR +G LYRG+ P
Sbjct: 383 CGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPN 442
Query: 88 LMQKTTTLALMFGLYEDLSCLL 109
M+ +++ + +YE+L L
Sbjct: 443 FMKVIPAVSISYVVYENLKITL 464
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 48.1 bits (113), Expect = 9e-06
Identities = 50/179 (27%), Positives = 78/179 (43%), Gaps = 18/179 (10%)
Query: 122 GVAAVLAGTAEAIFTPLERVQTLLQNHK-HHDKFTNTYQAFKAL-KCHGIGEYYRGLVPI 179
GVA VL G P + V+ LQ ++ T FK++ K + Y+GL
Sbjct: 12 GVAGVLVGH------PFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSP 65
Query: 180 LFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRL 239
L N L FG++G + A H + L N F+ G GA+ +C P+ + KTRL
Sbjct: 66 LMGLTFINALVFGVQG----NTLRALGHDSPL-NQFLAGAAAGAIQCVICCPMELAKTRL 120
Query: 240 QSQIGGEFQSFP---KVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLK 295
Q Q G +++ +I+ + +N RG R S+G+ TY+ L +
Sbjct: 121 QLQDAGPARTYKGSLDCLAQIYGHEGLRGVN--RGMVSTLLRETPSFGVYFLTYDALTR 177
Score = 45.4 bits (106), Expect = 6e-05
Identities = 53/223 (23%), Positives = 89/223 (39%), Gaps = 23/223 (10%)
Query: 34 YLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRD--AVLQ-----LRRDGFRNLYRGILP 86
+L GC V + +P V R Q+ ++ L ++++ LY+G+
Sbjct: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGS 64
Query: 87 PLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTAEAIF-TPLERVQTLL 145
PLM T AL+FG+ + L +F +A AG + + P+E +T L
Sbjct: 65 PLMGLTFINALVFGVQGNTLRALGHDSPLNQF----LAGAAAGAIQCVICCPMELAKTRL 120
Query: 146 QNHKHHDKFTNTYQAFKALKC-------HGIGEYYRGLVPILFRNGLSNVLFFGLRGPIK 198
Q TY+ +L C G+ RG+V L R S ++F +
Sbjct: 121 QLQDAGP--ARTYKG--SLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALT 176
Query: 199 EHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQS 241
L + + GG G + +P++VVK+RLQ+
Sbjct: 177 RALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQA 219
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 48.1 bits (113), Expect = 9e-06
Identities = 60/277 (21%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 85 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 144
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGT-AEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG A++ P+E ++T
Sbjct: 145 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 204
Query: 145 LQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKEH 200
+ K A + L G+ +Y+G VP I+ G+ ++ L+ +H
Sbjct: 205 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 264
Query: 201 LPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQK 256
+ V + G + + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 265 YAVNSADPGVFV--LLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 322
Query: 257 IWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
I R L+RG N+ + + + I YE L
Sbjct: 323 IL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 357
Score = 29.6 bits (65), Expect = 3.3
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 36 CGCCAAFNNVAITYPIQKVLFRQQLYGI------KTRDAVLQ--LRRDGFRNLYRGILPP 87
CG ++ +YP+ V R Q T ++ + LR +G LYRG+ P
Sbjct: 280 CGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPN 339
Query: 88 LMQKTTTLALMFGLYEDLSCLL 109
M+ +++ + +YE+L L
Sbjct: 340 FMKVIPAVSISYVVYENLKITL 361
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 48.1 bits (113), Expect = 9e-06
Identities = 60/277 (21%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVL------QLRRDGFRNLYRGIL 85
+H + G A + T P+ ++ Q++ ++ + + +R G R+L+RG
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 281
Query: 86 PPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGT-AEAIFTPLERVQTL 144
+++ A+ F YE + L+ VA LAG A++ P+E ++T
Sbjct: 282 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 341
Query: 145 LQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVP----ILFRNGLSNVLFFGLRGPIKEH 200
+ K A + L G+ +Y+G VP I+ G+ ++ L+ +H
Sbjct: 342 MALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 401
Query: 201 LPTATTHSAHLVNDFIGGGLLGAMLGFLC-FPINVVKTRLQSQI---GGEFQSFPKVFQK 256
+ V + G + + G L +P+ +V+TR+Q+Q G + +F+
Sbjct: 402 YAVNSADPGVFV--LLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 459
Query: 257 IWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFL 293
I R L+RG N+ + + + I YE L
Sbjct: 460 IL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 494
Score = 29.6 bits (65), Expect = 3.3
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 36 CGCCAAFNNVAITYPIQKVLFRQQLYGI------KTRDAVLQ--LRRDGFRNLYRGILPP 87
CG ++ +YP+ V R Q T ++ + LR +G LYRG+ P
Sbjct: 417 CGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPN 476
Query: 88 LMQKTTTLALMFGLYEDLSCLL 109
M+ +++ + +YE+L L
Sbjct: 477 FMKVIPAVSISYVVYENLKITL 498
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 47.0 bits (110), Expect = 2e-05
Identities = 45/187 (24%), Positives = 85/187 (45%), Gaps = 13/187 (6%)
Query: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGT- 130
+R +G R+LY G++ L ++ + ++ GLY+ + + + + E A+ G + +LAG+
Sbjct: 70 VRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVK---QFYTKGSEHASIG-SRLLAGST 125
Query: 131 ----AEAIFTPLERVQTLLQNHKHHD---KFTNTYQAFKAL-KCHGIGEYYRGLVPILFR 182
A A+ P + V+ Q ++ +T A+K + + G ++G P + R
Sbjct: 126 TGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVAR 185
Query: 183 NGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQ 242
N + N IK+ L A + L F G + P++VVKTR +
Sbjct: 186 NAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNS 245
Query: 243 IGGEFQS 249
G++ S
Sbjct: 246 ALGQYSS 252
Score = 42.0 bits (97), Expect = 7e-04
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 2/136 (1%)
Query: 73 RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLS-CLLRKHVRAPEFATHGVAAVLAGTA 131
R +GFR L++G P + + Y+ + LL+ ++ + H +A AG
Sbjct: 168 REEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFC 227
Query: 132 EAIF-TPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLF 190
+ +P++ V+T N + + A L+ G +Y+G +P R G NV+
Sbjct: 228 TTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVM 287
Query: 191 FGLRGPIKEHLPTATT 206
F +K L A T
Sbjct: 288 FVTYEQLKRALMAACT 303
Score = 30.0 bits (66), Expect = 2.6
Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 5/78 (6%)
Query: 33 HYLCGCCAAFNNVAITYPIQKVLFRQQ-----LYGIKTRDAVLQLRRDGFRNLYRGILPP 87
H+ A F I P+ V R Y A+ L+++G R Y+G +P
Sbjct: 217 HFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPS 276
Query: 88 LMQKTTTLALMFGLYEDL 105
++ + +MF YE L
Sbjct: 277 FLRLGSWNVVMFVTYEQL 294
>gi|41462412 solute carrier family 25, member 35 [Homo sapiens]
Length = 295
Score = 47.0 bits (110), Expect = 2e-05
Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 36/172 (20%)
Query: 127 LAGTAEAIFT-PLERVQTLLQ---------NHKHHDKFTNTYQAFKAL-KCHGIGEYYRG 175
LA +FT PLE V+T +Q ++ H + N + AF + K G+ +G
Sbjct: 8 LAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRH--YRNVFHAFITIGKVDGLAALQKG 65
Query: 176 LVPILFRNGLSNVLFFGLRGPIKE--HLPTAT-THSAHLVNDFIGGGLLGAMLGFLCFPI 232
L P L L N + G G + +L TA THS G + G M +L PI
Sbjct: 66 LAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSP--ARSAAAGAMAGVMGAYLGSPI 123
Query: 233 NVVKTRLQSQIGGE------------FQSFPKVFQKIWLERDRKLINLFRGA 272
+VKT LQ+Q E FQ+ ++ QK L+ L+RGA
Sbjct: 124 YMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQK------HGLVGLWRGA 169
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 46.6 bits (109), Expect = 3e-05
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 15/240 (6%)
Query: 65 TRDAVLQL-RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGV 123
T DA +++ R +G R L+ G+ L+ A+ F Y+ L L + V
Sbjct: 99 TMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMV 158
Query: 124 AAVLA--GTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFK-ALKCHGIGEYYRGLVPIL 180
A LA GT I +PLE ++T LQ H + + A+ G + G P
Sbjct: 159 AGALARLGTVTVI-SPLELMRTKLQ--AQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 215
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVN-DFIGGGLLGAMLGFLCFPINVVKTRL 239
R+ + L++ +K L V F+ GG+ G + L P +VVKT+
Sbjct: 216 LRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQR 275
Query: 240 QSQIGG--EFQSFPKVFQKIWL-----ERDRKLINLFRGAHLNYHRSLISWGIINATYEF 292
Q +G + P WL + LF G ++ S I+ +TYEF
Sbjct: 276 QVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEF 335
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 46.6 bits (109), Expect = 3e-05
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 15/240 (6%)
Query: 65 TRDAVLQL-RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGV 123
T DA +++ R +G R L+ G+ L+ A+ F Y+ L L + V
Sbjct: 107 TMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMV 166
Query: 124 AAVLA--GTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFK-ALKCHGIGEYYRGLVPIL 180
A LA GT I +PLE ++T LQ H + + A+ G + G P
Sbjct: 167 AGALARLGTVTVI-SPLELMRTKLQ--AQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 223
Query: 181 FRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVN-DFIGGGLLGAMLGFLCFPINVVKTRL 239
R+ + L++ +K L V F+ GG+ G + L P +VVKT+
Sbjct: 224 LRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQR 283
Query: 240 QSQIGG--EFQSFPKVFQKIWL-----ERDRKLINLFRGAHLNYHRSLISWGIINATYEF 292
Q +G + P WL + LF G ++ S I+ +TYEF
Sbjct: 284 QVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEF 343
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 46.2 bits (108), Expect = 3e-05
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 2/121 (1%)
Query: 73 RRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLS-CLLRKHVRAPEFATHGVAAVLAG-T 130
R +G R L++G LP +M+ Y+ L LL H+ F H V+A AG
Sbjct: 171 REEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFC 230
Query: 131 AEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLF 190
A + +P++ V+T N F+ K + G +Y+G P R G NV+
Sbjct: 231 ATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVM 290
Query: 191 F 191
F
Sbjct: 291 F 291
Score = 42.4 bits (98), Expect = 5e-04
Identities = 54/245 (22%), Positives = 104/245 (42%), Gaps = 42/245 (17%)
Query: 37 GCCAAFNNVAITYPIQKVLFRQQLYG----IKTRDAV----------LQLRRDGFRNLYR 82
G A F ++ +T+P+ R Q+ G ++T V +R +G + Y
Sbjct: 21 GTAACFADL-VTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYN 79
Query: 83 GILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHG--VAAVLAG-----TAEAIF 135
G++ L ++ + ++ GLY+ + K V P+ A + +LAG A
Sbjct: 80 GLVAGLQRQMSFASIRIGLYDSV-----KQVYTPKGADNSSLTTRILAGCTTGAMAVTCA 134
Query: 136 TPLERVQTLLQNHKH------HDKFTNTYQAFKAL-KCHGIGEYYRGLVPILFRNGLSN- 187
P + V+ Q H K++ T A++ + + G+ ++G +P + RN + N
Sbjct: 135 QPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNC 194
Query: 188 ---VLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQIG 244
V + L+ + ++ H V+ F G G + + P++VVKTR +
Sbjct: 195 AEVVTYDILKEKLLDYHLLTDNFPCHFVSAF-GAGFCATV---VASPVDVVKTRYMNSPP 250
Query: 245 GEFQS 249
G++ S
Sbjct: 251 GQYFS 255
>gi|5453918 solute carrier family 25 (mitochondrial carrier;
peroxisomal membrane protein, 34kDa), member 17 [Homo
sapiens]
Length = 307
Score = 46.2 bits (108), Expect = 3e-05
Identities = 51/184 (27%), Positives = 75/184 (40%), Gaps = 25/184 (13%)
Query: 32 KHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTR-------------DAVLQLRRD-GF 77
K + G A NV +T P+ V R +L G K R DA Q+ RD G
Sbjct: 103 KDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGI 162
Query: 78 RNLYRGILPPLMQKTTTLALMFGLYEDLSC-LLRKHVRAPEFATHGVAAVLAGTAEAIFT 136
L+ G P L+ A+ F YE L LL+K ++ + AV A +
Sbjct: 163 SALWNGTFPSLLLVFNP-AIQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTY 221
Query: 137 PLERVQTLLQNHKHHDKFTN---------TYQAFKALKCHGIGEYYRGLVPILFRNGLSN 187
PL+ VQ++L+ +H N Y + ++ GI Y+GL L + L+
Sbjct: 222 PLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTA 281
Query: 188 VLFF 191
L F
Sbjct: 282 ALMF 285
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
Query: 117 EFATHGVA-AVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRG 175
E H VA AV + TA +F PL+ + LQ + T + +K G+ YRG
Sbjct: 8 ESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRG 67
Query: 176 LVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVV 235
P++ SN ++F +K L HS D + G + G + L P+ VV
Sbjct: 68 WFPVISSLCCSNFVYFYTFNSLKA-LWVKGQHST-TGKDLVVGFVAGVVNVLLTTPLWVV 125
Query: 236 KTRLQSQIGGEFQS 249
TRL+ Q G +F++
Sbjct: 126 NTRLKLQ-GAKFRN 138
Score = 35.8 bits (81), Expect = 0.047
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 34 YLCGCCAAFNNVAITYPIQKV--LFRQQLYGIKTRDAVL------------QLRRDGFRN 79
++ G A +TYP+Q V + R + + + L ++RR G
Sbjct: 206 FIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNILYLLHQRVRRFGIMG 265
Query: 80 LYRGILPPLMQKTTTLALMFGLYEDLS 106
LY+G+ L+Q T ALMF +YE L+
Sbjct: 266 LYKGLEAKLLQTVLTAALMFLVYEKLT 292
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 45.4 bits (106), Expect = 6e-05
Identities = 52/225 (23%), Positives = 86/225 (38%), Gaps = 17/225 (7%)
Query: 34 YLCGCCAAFNNVAITYPIQKVLFRQQLYG--IKTRDAVLQ-------LRRDGFRNLYRGI 84
+L G A P+ V R QL G KTR+ L+ +G R +Y G+
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGL 84
Query: 85 LPPLMQKTTTLALMFGLYEDL-SCLLRKHVRAPEFATHGVAAVLAGTAEA-IFTPLE--R 140
L+++ T G+Y L L P F V + AG A + TP E
Sbjct: 85 SAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVAL 144
Query: 141 VQTLLQNHKHHDKFTNTYQAFKAL----KCHGIGEYYRGLVPILFRNGLSNVLFFGLRGP 196
++ D+ F AL + G+ +RG +P + R + N
Sbjct: 145 IRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQ 204
Query: 197 IKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQS 241
K+ L + S +++ F + G + P+++ KTR+Q+
Sbjct: 205 SKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQN 249
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.142 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,781,401
Number of Sequences: 37866
Number of extensions: 435414
Number of successful extensions: 1359
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 1144
Number of HSP's gapped (non-prelim): 183
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.