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Search of human proteins with 148226324
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148226324 protein tyrosine phosphatase-like A domain
containing 2 [Homo sapiens]
(232 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148226324 protein tyrosine phosphatase-like A domain containi... 474 e-134
gi|117168248 protein tyrosine phosphatase-like A domain containi... 195 2e-50
gi|38257153 protein tyrosine phosphatase-like (proline instead o... 99 3e-21
gi|82659105 protein tyrosine phosphatase-like, member A [Homo sa... 83 2e-16
gi|239750861 PREDICTED: hypothetical protein XP_002347581 [Homo ... 46 3e-05
gi|59709427 XK, Kell blood group complex subunit-related family,... 33 0.21
gi|94158915 progestin and adipoQ receptor family member III [Hom... 30 2.3
gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] 28 5.1
gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] 28 5.1
gi|14043062 angiotensin II receptor, type 1 [Homo sapiens] 28 5.1
gi|6715583 angiotensin II receptor, type 1 [Homo sapiens] 28 5.1
gi|4501997 angiotensin II receptor, type 1 [Homo sapiens] 28 5.1
gi|93141214 sodium channel, voltage-gated, type II, alpha isofor... 28 8.7
gi|93141212 sodium channel, voltage-gated, type II, alpha isofor... 28 8.7
gi|93141210 sodium channel, voltage-gated, type II, alpha isofor... 28 8.7
>gi|148226324 protein tyrosine phosphatase-like A domain containing
2 [Homo sapiens]
Length = 232
Score = 474 bits (1220), Expect = e-134
Identities = 232/232 (100%), Positives = 232/232 (100%)
Query: 1 MGPLALPAWLQPRYRKNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLV 60
MGPLALPAWLQPRYRKNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLV
Sbjct: 1 MGPLALPAWLQPRYRKNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLV 60
Query: 61 MRLCQSVSLLELLHIYVGIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVF 120
MRLCQSVSLLELLHIYVGIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVF
Sbjct: 61 MRLCQSVSLLELLHIYVGIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVF 120
Query: 121 WNLLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYFESFGTY 180
WNLLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYFESFGTY
Sbjct: 121 WNLLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYFESFGTY 180
Query: 181 STKLPFDLSIYFPYVLKIYLMMLFIGMYFTYSHLYSERRDILGIFPIKKKKM 232
STKLPFDLSIYFPYVLKIYLMMLFIGMYFTYSHLYSERRDILGIFPIKKKKM
Sbjct: 181 STKLPFDLSIYFPYVLKIYLMMLFIGMYFTYSHLYSERRDILGIFPIKKKKM 232
>gi|117168248 protein tyrosine phosphatase-like A domain containing
1 [Homo sapiens]
Length = 362
Score = 195 bits (496), Expect = 2e-50
Identities = 92/219 (42%), Positives = 144/219 (65%), Gaps = 5/219 (2%)
Query: 16 KNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLVMRLCQSVSLLELLHI 75
+ YLF+Y L+QF G SWIF N+TVRF GK+S DTF+ + +M CQ ++++E ++
Sbjct: 146 RKGYLFMYNLVQFLGFSWIFVNLTVRFCILGKESFYDTFHTVADMMYFCQMLAVVETINA 205
Query: 76 YVGIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVFWNLLDMVRYTYSMLS 135
+G+ ++ +LP +QL R ILF++ + EE+Q K VV +F W+ +++ RY++ ML+
Sbjct: 206 AIGVTTSPVLPSLIQLLGRNFILFIIFGTMEEMQNKAVVFFVFYLWSAIEIFRYSFYMLT 265
Query: 136 VIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYFESFGTYSTKLPF--DLSIYFP 193
I + + VLTWL TLW+P+YPL LAEA ++ QS+P F G +S LP+ + + F
Sbjct: 266 CIDMDWKVLTWLRYTLWIPLYPLGCLAEAVSVIQSIPIFNETGRFSFTLPYPVKIKVRFS 325
Query: 194 YVLKIYLMMLFIGMYFTYSHLYSERRDILGIFPIKKKKM 232
+ L+IYL+M+F+G+Y + HLY +RR G KKKK+
Sbjct: 326 FFLQIYLIMIFLGLYINFRHLYKQRRRRYG---QKKKKI 361
>gi|38257153 protein tyrosine phosphatase-like (proline instead of
catalytic arginine), member b [Homo sapiens]
Length = 254
Score = 99.0 bits (245), Expect = 3e-21
Identities = 58/207 (28%), Positives = 105/207 (50%), Gaps = 4/207 (1%)
Query: 18 AYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLVMRLCQSVSLLELLHIYV 77
AYL IY ++ G W+ + + K S +Y+I ++ Q+ +LLE+LH +
Sbjct: 40 AYLVIYNVVMTAG--WLVIAVGLVRAYLAKGSYHSLYYSIEKPLKFFQTGALLEILHCAI 97
Query: 78 GIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVFWNLLDMVRYTYSMLSVI 137
GI + ++ Q+ R+ +++ V S +EVQ + V + + W + +++RY++ S++
Sbjct: 98 GIVPSSVVLTSFQVMSRVFLIWAVTHSVKEVQSEDSVLLFVIAWTITEIIRYSFYTFSLL 157
Query: 138 GISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYFESFGTYSTKLPFDLSIYFPYVLK 197
++ W TL++ +YP+ V E IY +LP+ G YS LP + F Y
Sbjct: 158 NHLPYLIKWARYTLFIVLYPMGVSGELLTIYAALPFVRQAGLYSISLPNKYNFSFDYYAF 217
Query: 198 IYLMMLFIGMYF--TYSHLYSERRDIL 222
+ L+M+ F Y H+ +RR IL
Sbjct: 218 LILIMISYIPIFPQLYFHMIHQRRKIL 244
>gi|82659105 protein tyrosine phosphatase-like, member A [Homo
sapiens]
Length = 288
Score = 83.2 bits (204), Expect = 2e-16
Identities = 50/210 (23%), Positives = 104/210 (49%), Gaps = 10/210 (4%)
Query: 18 AYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLVMRLCQSVSLLELLHIYV 77
A+L Y + G W+ + + F K + + +I ++ Q+ +LLE++H +
Sbjct: 74 AWLTFYDIAMTAG--WLVLAIAMVRFYMEKGTHRGLYKSIQKTLKFFQTFALLEIVHCLI 131
Query: 78 GIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVFWNLLDMVRYTYSMLSVI 137
GI ++ +Q++ RI +++++ S + +Q + V + V W + ++ RY++ S++
Sbjct: 132 GIVPTSVIVTGVQVSSRIFMVWLITHSIKPIQNEESVVLFLVAWTVTEITRYSFYTFSLL 191
Query: 138 GISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYFESFGTYSTKLPFDLSIYFPYVLK 197
+ W ++ +YP+ V E IY +LP+ + G +S +LP ++ F Y
Sbjct: 192 DHLPYFIKWARYNFFIILYPVGVAGELLTIYAALPHVKKTGMFSIRLPNKYNVSFDYYYF 251
Query: 198 IYLMM-----LFIGMYFTYSHLYSERRDIL 222
+ + M LF +YF H+ +RR +L
Sbjct: 252 LLITMASYIPLFPQLYF---HMLRQRRKVL 278
>gi|239750861 PREDICTED: hypothetical protein XP_002347581 [Homo
sapiens]
Length = 190
Score = 45.8 bits (107), Expect = 3e-05
Identities = 19/32 (59%), Positives = 23/32 (71%)
Query: 16 KNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGK 47
+ YLF+Y L+QF G SWIF N+TVRF GK
Sbjct: 146 RKGYLFMYNLVQFLGFSWIFVNLTVRFCILGK 177
>gi|59709427 XK, Kell blood group complex subunit-related family,
member 4 [Homo sapiens]
Length = 650
Score = 33.1 bits (74), Expect = 0.21
Identities = 34/164 (20%), Positives = 67/164 (40%), Gaps = 26/164 (15%)
Query: 16 KNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLVMRLCQSVSLLELLHI 75
K ++ +IQFC H + + F F S+ ++ I +V+ C + ++H
Sbjct: 364 KKPISYMAVIIQFCWHFFTIAARVITFALFA--SVFQLYFGIFIVLHWC--IMTFWIVH- 418
Query: 76 YVGIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVFWNLLDMVRYTYSMLS 135
E+ + ++ ++ +++ + I S V+E C LF+++ ++ + S
Sbjct: 419 ---CETEFCITKWEEIVFDMVVGIIYIFSWFNVKEGRTRCRLFIYYFVILLENTALS--- 472
Query: 136 VIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYFESFGT 179
LW +Y +A+AFAI F SF T
Sbjct: 473 --------------ALWY-LYKAPQIADAFAIPALCVVFSSFLT 501
>gi|94158915 progestin and adipoQ receptor family member III [Homo
sapiens]
Length = 311
Score = 29.6 bits (65), Expect = 2.3
Identities = 38/142 (26%), Positives = 54/142 (38%), Gaps = 33/142 (23%)
Query: 55 YAIGLVMRLCQSVSLLELLHIYVGIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVV 114
Y L RLC SL L + V I S HLL FL T I + V+ S +E +V+
Sbjct: 50 YRAYLPSRLCIK-SLFILSNETVNIWS-HLLGFFLFFTLGIYDMTSVLPSASASREDFVI 107
Query: 115 CVLFVF--------------------------WNLLDMVRYTYSMLS--VIGISYAVLTW 146
C + +F W LD + +L V G+ YA +
Sbjct: 108 CSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVSGVFYA---F 164
Query: 147 LSQTLWMPIYPLCVLAEAFAIY 168
W +Y + VLA A++
Sbjct: 165 YCNNYWRQVYLITVLAMILAVF 186
>gi|14043066 angiotensin II receptor, type 1 [Homo sapiens]
Length = 359
Score = 28.5 bits (62), Expect = 5.1
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 113 VVCVLFVFWN-LLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSL 171
++ V+ +F N L+ +V Y Y L + + + L+ ++ PL +A+Y ++
Sbjct: 37 IIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPL------WAVYTAM 90
Query: 172 PYFESFGTYSTKLPFDLSIYFPYVLKIYLM-MLFIGMYFTYSHLYSER 218
Y FG Y K+ S+ F ++L+ L I Y H R
Sbjct: 91 EYRWPFGNYLCKIA-SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSR 137
>gi|14043064 angiotensin II receptor, type 1 [Homo sapiens]
Length = 359
Score = 28.5 bits (62), Expect = 5.1
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 113 VVCVLFVFWN-LLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSL 171
++ V+ +F N L+ +V Y Y L + + + L+ ++ PL +A+Y ++
Sbjct: 37 IIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPL------WAVYTAM 90
Query: 172 PYFESFGTYSTKLPFDLSIYFPYVLKIYLM-MLFIGMYFTYSHLYSER 218
Y FG Y K+ S+ F ++L+ L I Y H R
Sbjct: 91 EYRWPFGNYLCKIA-SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSR 137
>gi|14043062 angiotensin II receptor, type 1 [Homo sapiens]
Length = 359
Score = 28.5 bits (62), Expect = 5.1
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 113 VVCVLFVFWN-LLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSL 171
++ V+ +F N L+ +V Y Y L + + + L+ ++ PL +A+Y ++
Sbjct: 37 IIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPL------WAVYTAM 90
Query: 172 PYFESFGTYSTKLPFDLSIYFPYVLKIYLM-MLFIGMYFTYSHLYSER 218
Y FG Y K+ S+ F ++L+ L I Y H R
Sbjct: 91 EYRWPFGNYLCKIA-SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSR 137
>gi|6715583 angiotensin II receptor, type 1 [Homo sapiens]
Length = 359
Score = 28.5 bits (62), Expect = 5.1
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 113 VVCVLFVFWN-LLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSL 171
++ V+ +F N L+ +V Y Y L + + + L+ ++ PL +A+Y ++
Sbjct: 37 IIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPL------WAVYTAM 90
Query: 172 PYFESFGTYSTKLPFDLSIYFPYVLKIYLM-MLFIGMYFTYSHLYSER 218
Y FG Y K+ S+ F ++L+ L I Y H R
Sbjct: 91 EYRWPFGNYLCKIA-SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSR 137
>gi|4501997 angiotensin II receptor, type 1 [Homo sapiens]
Length = 359
Score = 28.5 bits (62), Expect = 5.1
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 113 VVCVLFVFWN-LLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSL 171
++ V+ +F N L+ +V Y Y L + + + L+ ++ PL +A+Y ++
Sbjct: 37 IIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPL------WAVYTAM 90
Query: 172 PYFESFGTYSTKLPFDLSIYFPYVLKIYLM-MLFIGMYFTYSHLYSER 218
Y FG Y K+ S+ F ++L+ L I Y H R
Sbjct: 91 EYRWPFGNYLCKIA-SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSR 137
>gi|93141214 sodium channel, voltage-gated, type II, alpha isoform 2
[Homo sapiens]
Length = 2005
Score = 27.7 bits (60), Expect = 8.7
Identities = 10/31 (32%), Positives = 19/31 (61%)
Query: 10 LQPRYRKNAYLFIYYLIQFCGHSWIFTNMTV 40
LQP+Y N Y+++Y++I S+ N+ +
Sbjct: 1439 LQPKYEDNLYMYLYFVIFIIFGSFFTLNLFI 1469
>gi|93141212 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 27.7 bits (60), Expect = 8.7
Identities = 10/31 (32%), Positives = 19/31 (61%)
Query: 10 LQPRYRKNAYLFIYYLIQFCGHSWIFTNMTV 40
LQP+Y N Y+++Y++I S+ N+ +
Sbjct: 1439 LQPKYEDNLYMYLYFVIFIIFGSFFTLNLFI 1469
>gi|93141210 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 27.7 bits (60), Expect = 8.7
Identities = 10/31 (32%), Positives = 19/31 (61%)
Query: 10 LQPRYRKNAYLFIYYLIQFCGHSWIFTNMTV 40
LQP+Y N Y+++Y++I S+ N+ +
Sbjct: 1439 LQPKYEDNLYMYLYFVIFIIFGSFFTLNLFI 1469
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.333 0.146 0.463
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,853,042
Number of Sequences: 37866
Number of extensions: 294113
Number of successful extensions: 1141
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1131
Number of HSP's gapped (non-prelim): 16
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.