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Search of human proteins with 14211851
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14211851 G protein-coupled receptor 81 [Homo sapiens]
(346 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14211851 G protein-coupled receptor 81 [Homo sapiens] 718 0.0
gi|157738694 G protein-coupled receptor 109B [Homo sapiens] 345 3e-95
gi|29171311 G protein-coupled receptor 109A [Homo sapiens] 342 4e-94
gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens] 203 2e-52
gi|153792268 G protein-coupled receptor 31 [Homo sapiens] 174 1e-43
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 139 3e-33
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 134 1e-31
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 129 4e-30
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 127 1e-29
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 127 1e-29
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 127 1e-29
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 127 1e-29
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 122 6e-28
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 122 6e-28
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 122 6e-28
gi|33695097 G protein-coupled receptor 35 [Homo sapiens] 120 1e-27
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 115 6e-26
gi|149944554 somatostatin receptor 4 [Homo sapiens] 115 8e-26
gi|4557857 somatostatin receptor 1 [Homo sapiens] 113 2e-25
gi|4557859 somatostatin receptor 2 [Homo sapiens] 113 2e-25
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 112 5e-25
gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 112 6e-25
gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 112 6e-25
gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 112 6e-25
gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens] 110 1e-24
gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens] 110 1e-24
gi|4557359 bradykinin receptor B2 [Homo sapiens] 110 2e-24
gi|148225857 G protein-coupled receptor 34 [Homo sapiens] 110 2e-24
gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ... 110 2e-24
gi|4885319 G protein-coupled receptor 34 [Homo sapiens] 110 2e-24
>gi|14211851 G protein-coupled receptor 81 [Homo sapiens]
Length = 346
Score = 718 bits (1853), Expect = 0.0
Identities = 346/346 (100%), Positives = 346/346 (100%)
Query: 1 MYNGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVA 60
MYNGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVA
Sbjct: 1 MYNGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVA 60
Query: 61 DFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHP 120
DFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHP
Sbjct: 61 DFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHP 120
Query: 121 HHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIM 180
HHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIM
Sbjct: 121 HHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIM 180
Query: 181 FQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSAR 240
FQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSAR
Sbjct: 181 FQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSAR 240
Query: 241 LYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK 300
LYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK
Sbjct: 241 LYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK 300
Query: 301 QPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDPHIVEWH 346
QPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDPHIVEWH
Sbjct: 301 QPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDPHIVEWH 346
>gi|157738694 G protein-coupled receptor 109B [Homo sapiens]
Length = 387
Score = 345 bits (886), Expect = 3e-95
Identities = 177/317 (55%), Positives = 223/317 (70%), Gaps = 6/317 (1%)
Query: 5 SCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLL 64
+CC D I++V+PP+L + F+ G LGNG+AL FCFH+K+WK S ++LFNLAVADFLL
Sbjct: 17 NCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLL 76
Query: 65 MICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAV 124
+ICLPF DYY+RR W FGDIPCR+ LF AMNR GSI+FLTVVA DRYF+VVHPHHA+
Sbjct: 77 IICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHAL 136
Query: 125 NTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLE 184
N IS AA I C LW + + TV+LL + L TA C SF + WH+ MF LE
Sbjct: 137 NKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLE 196
Query: 185 FFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYFL 244
FF+PLGIILFCS +I+WSLR+R Q+ R A++K+A FIMVVAIVF+ C+LPSV R++
Sbjct: 197 FFLPLGIILFCSARIIWSLRQR-QMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIHIF 255
Query: 245 WTVPSSA---CD--PSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKP 299
W + +S C+ SV A ITLSFTYMNSMLDP+VYYFSSPSFP F++ L L+
Sbjct: 256 WLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQR 315
Query: 300 KQPGHSKTQRPEEMPIS 316
K G R + ++
Sbjct: 316 KITGEPDNNRSTSVELT 332
>gi|29171311 G protein-coupled receptor 109A [Homo sapiens]
Length = 363
Score = 342 bits (876), Expect = 4e-94
Identities = 180/341 (52%), Positives = 227/341 (66%), Gaps = 7/341 (2%)
Query: 5 SCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLL 64
+CC D I +V+PP+L + F+ G LGNG+AL FCFH+K+WK S ++LFNLAVADFLL
Sbjct: 17 NCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLL 76
Query: 65 MICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAV 124
+ICLPF D Y+RR W FGDIPCR+ LF LAMNR GSI+FLTVVA DRYF+VVHPHHA+
Sbjct: 77 IICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHAL 136
Query: 125 NTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLE 184
N IS R AA I C LW + I TV+LL + A C SF + WH+ MF LE
Sbjct: 137 NKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLE 196
Query: 185 FFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYFL 244
FF+PLGIILFCS +I+WSLR+R Q+ R A++K+A FIMVVAIVF+ C+LPSV R+
Sbjct: 197 FFLPLGIILFCSARIIWSLRQR-QMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIF 255
Query: 245 WTVPSSA---CD--PSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKP 299
W + +S C+ SV A ITLSFTYMNSMLDP+VYYFSSPSFP F++ L L+
Sbjct: 256 WLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQR 315
Query: 300 KQPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDP 340
K G R + ++ ++ + + S W P
Sbjct: 316 KMTGEPDNNRSTSVELTGDPNKT-RGAPEALMANSGEPWSP 355
>gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]
Length = 423
Score = 203 bits (516), Expect = 2e-52
Identities = 113/289 (39%), Positives = 162/289 (56%), Gaps = 14/289 (4%)
Query: 4 GSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFL 63
G C +S + P+L + FVLG +GN +AL FC H + W +TV+L +L ADFL
Sbjct: 81 GPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFL 140
Query: 64 LMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHA 123
L+ LP R DYYL W FG C+V LF L+ NR S+VFLT +A +RY KVV PHH
Sbjct: 141 LISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHV 200
Query: 124 VNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIM----ESANGWHDI 179
++ S AA + LW ++L +LLL + SC S+ + ++ WH
Sbjct: 201 LSRASVGAAARVAGGLWVGILLLNGHLLLSTF-----SGPSCLSYRVGTKPSASLRWHQA 255
Query: 180 MFQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSV-- 237
++ LEFF+PL +ILF I ++R R L QA ++A R + +V V+ C+LPS+
Sbjct: 256 LYLLEFFLPLALILFAIVSIGLTIRNR-GLGGQAGPQRAMRVLAMVVAVYTICFLPSIIF 314
Query: 238 -SARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSF 285
A + W + D H +L+FTY+NS+LDP++Y FSSP+F
Sbjct: 315 GMASMVAFWLSACRSLDLCTQ-LFHGSLAFTYLNSVLDPVLYCFSSPNF 362
>gi|153792268 G protein-coupled receptor 31 [Homo sapiens]
Length = 319
Score = 174 bits (441), Expect = 1e-43
Identities = 99/293 (33%), Positives = 160/293 (54%), Gaps = 9/293 (3%)
Query: 7 CRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMI 66
C ++ + LL + LG LGN VAL F F ++ WKP VYL NLA+AD LL
Sbjct: 6 CSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAA 65
Query: 67 CLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNT 126
CLPF +YL + W G + C F L ++R+ + FL VA DRY +VVHP VN
Sbjct: 66 CLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNL 125
Query: 127 ISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANG----WHDIMFQ 182
+S + A G+ +W L++ T LL + + + C SF + W + +
Sbjct: 126 LSPQAALGVSGLVWLLMVALTCPGLLISE--AAQNSTRCHSFYSRADGSFSIIWQEALSC 183
Query: 183 LEFFMPLGIILFCSFKIVWSLRRR-QQLARQARMKKATRFIMVVAIVFITCYLPSVSAR- 240
L+F +P G+I+FC+ I+ +L++R ++ +Q ++++A + +V ++F C+LP AR
Sbjct: 184 LQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARV 243
Query: 241 -LYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKL 292
++ + S +V +T S TY++S+L+P+VY FSSP+F Y ++
Sbjct: 244 LMHIFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRV 296
>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
Length = 346
Score = 139 bits (351), Expect = 3e-33
Identities = 92/311 (29%), Positives = 157/311 (50%), Gaps = 11/311 (3%)
Query: 3 NGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADF 62
N C IE + P + ++ F G LGNG+++ F K V++ NLA++D
Sbjct: 27 NSRNCTIENFK-REFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDL 85
Query: 63 LLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHH 122
L + LPFR DYYLR +W FGD+ CR+ ++L +N SI FLTV++ R+ +VHP
Sbjct: 86 LFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFR 145
Query: 123 AVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSC---ESFIMESANGWHDI 179
++ S R +A I+C + ++I+ + +LL++ + SC + + + I
Sbjct: 146 LLHVTSIR-SAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYI 204
Query: 180 MFQLEFFMPLGIILFCSFKIVWSLRRRQ--QLARQARMKKATRFIMVVAIVFITCYLPSV 237
+ +P + C I+ L + + + + +KA I++ I+F C+LP
Sbjct: 205 ALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCFLPYH 264
Query: 238 SARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSL 297
+ R L T C +H AL ITL+ N+ +PL+YYF+ +F ++LK +L
Sbjct: 265 TLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFK---DRLK-SAL 320
Query: 298 KPKQPGHSKTQ 308
+ P +KT+
Sbjct: 321 RKGHPQKAKTK 331
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 134 bits (337), Expect = 1e-31
Identities = 86/280 (30%), Positives = 143/280 (51%), Gaps = 14/280 (5%)
Query: 18 MPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLR 77
+P + I+ F++G LGN VA+ F FHMK W +VY+FNLA+ADFL ++ LP YY
Sbjct: 54 LPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFN 113
Query: 78 RRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVC 137
+ W FGD C++ F +N GSI+FLT ++A RY VV+P ++ + + A I
Sbjct: 114 KTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISV 173
Query: 138 TLWALVILGTVYLLLENHLCVQET-AVSCESFIMESANGWHDIMFQLE----FFMPLGII 192
+W +V++ +L + V++ ++C + + I F +PL +I
Sbjct: 174 LVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLI 233
Query: 193 LFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLP-------SVSARLYFLW 245
L C IV +L + L +K+ +++V VF Y+P ++ ARL F
Sbjct: 234 LGCYGLIVRALIYK-DLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDF-Q 291
Query: 246 TVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSF 285
T A + V+ +T +NS +DP++Y+ + +F
Sbjct: 292 TPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTF 331
>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
Length = 370
Score = 129 bits (324), Expect = 4e-30
Identities = 90/281 (32%), Positives = 139/281 (49%), Gaps = 21/281 (7%)
Query: 24 VAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAF 83
V F+LG + N V+L FCF MK + +++ NLAV+D L + LPF+ +Y RHW F
Sbjct: 48 VVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKI-FYNFNRHWPF 106
Query: 84 GDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCT-LWAL 142
GD C++ N GS++FLT ++ DR+ +V+P + TI TR + IVC +W L
Sbjct: 107 GDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRS-RTIRTRRNSAIVCAGVWIL 165
Query: 143 VILGTVYLLLENHLCVQETAVSC-ESFIMESANGWHDIMFQLE-------FFMPLGIILF 194
V+ G + L + V +C E F S W + ++ F +PL + +
Sbjct: 166 VLSGGISASLFSTTNVNNATTTCFEGF---SKRVWKTYLSKITIFIEVVGFIIPLILNVS 222
Query: 195 CSFKIVWSLRRRQQLAR-QARMKKATRFIMVVAIVFITCYLPSVSARLYFLWTVPSSA-- 251
CS ++ +LR+ L++ KK + I V VF+ C++P S L+ V S A
Sbjct: 223 CSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSV-LFLYALVRSQAIT 281
Query: 252 ---CDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFY 289
+ ITL +N DP +YYF+ SF K +
Sbjct: 282 NCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSF 322
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 127 bits (320), Expect = 1e-29
Identities = 95/316 (30%), Positives = 150/316 (47%), Gaps = 10/316 (3%)
Query: 7 CRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMI 66
C E + + ++ F+L +GN +AL F K+ P+ V+L +LAVAD ++
Sbjct: 23 CGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVL 82
Query: 67 CLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNT 126
LP R Y+ HW FG+I CR+ F +N SI FLT ++ADR+ +VHP ++
Sbjct: 83 VLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLK- 141
Query: 127 ISTRVAAGIVCT-LWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLEF 185
+ + A + C LW +V + LL+ V C E A+ + + F
Sbjct: 142 LRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAF 201
Query: 186 FMPLGIILFCSFKIVWSLRRRQQLARQARMK-KATRFIMVVAIVFITCYLP-SVSARLYF 243
P + C I+ SL RQ L + R+K KA R I +V +F+ C++P V+ +Y
Sbjct: 202 TFPFITTVTCYLLIIRSL--RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 259
Query: 244 L-WTVPSSACDPSVHGAL--HITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK 300
L + ++C AL IT T +N LDP++Y+F + F L +C + K
Sbjct: 260 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL-LCGKRLK 318
Query: 301 QPGHSKTQRPEEMPIS 316
P S + E +S
Sbjct: 319 GPPPSFEGKTNESSLS 334
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 127 bits (320), Expect = 1e-29
Identities = 95/316 (30%), Positives = 150/316 (47%), Gaps = 10/316 (3%)
Query: 7 CRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMI 66
C E + + ++ F+L +GN +AL F K+ P+ V+L +LAVAD ++
Sbjct: 23 CGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVL 82
Query: 67 CLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNT 126
LP R Y+ HW FG+I CR+ F +N SI FLT ++ADR+ +VHP ++
Sbjct: 83 VLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLK- 141
Query: 127 ISTRVAAGIVCT-LWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLEF 185
+ + A + C LW +V + LL+ V C E A+ + + F
Sbjct: 142 LRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAF 201
Query: 186 FMPLGIILFCSFKIVWSLRRRQQLARQARMK-KATRFIMVVAIVFITCYLP-SVSARLYF 243
P + C I+ SL RQ L + R+K KA R I +V +F+ C++P V+ +Y
Sbjct: 202 TFPFITTVTCYLLIIRSL--RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 259
Query: 244 L-WTVPSSACDPSVHGAL--HITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK 300
L + ++C AL IT T +N LDP++Y+F + F L +C + K
Sbjct: 260 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL-LCGKRLK 318
Query: 301 QPGHSKTQRPEEMPIS 316
P S + E +S
Sbjct: 319 GPPPSFEGKTNESSLS 334
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 127 bits (320), Expect = 1e-29
Identities = 95/316 (30%), Positives = 150/316 (47%), Gaps = 10/316 (3%)
Query: 7 CRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMI 66
C E + + ++ F+L +GN +AL F K+ P+ V+L +LAVAD ++
Sbjct: 51 CGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVL 110
Query: 67 CLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNT 126
LP R Y+ HW FG+I CR+ F +N SI FLT ++ADR+ +VHP ++
Sbjct: 111 VLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLK- 169
Query: 127 ISTRVAAGIVCT-LWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLEF 185
+ + A + C LW +V + LL+ V C E A+ + + F
Sbjct: 170 LRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAF 229
Query: 186 FMPLGIILFCSFKIVWSLRRRQQLARQARMK-KATRFIMVVAIVFITCYLP-SVSARLYF 243
P + C I+ SL RQ L + R+K KA R I +V +F+ C++P V+ +Y
Sbjct: 230 TFPFITTVTCYLLIIRSL--RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 287
Query: 244 L-WTVPSSACDPSVHGAL--HITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK 300
L + ++C AL IT T +N LDP++Y+F + F L +C + K
Sbjct: 288 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL-LCGKRLK 346
Query: 301 QPGHSKTQRPEEMPIS 316
P S + E +S
Sbjct: 347 GPPPSFEGKTNESSLS 362
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 127 bits (320), Expect = 1e-29
Identities = 95/316 (30%), Positives = 150/316 (47%), Gaps = 10/316 (3%)
Query: 7 CRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMI 66
C E + + ++ F+L +GN +AL F K+ P+ V+L +LAVAD ++
Sbjct: 51 CGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVL 110
Query: 67 CLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNT 126
LP R Y+ HW FG+I CR+ F +N SI FLT ++ADR+ +VHP ++
Sbjct: 111 VLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLK- 169
Query: 127 ISTRVAAGIVCT-LWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLEF 185
+ + A + C LW +V + LL+ V C E A+ + + F
Sbjct: 170 LRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAF 229
Query: 186 FMPLGIILFCSFKIVWSLRRRQQLARQARMK-KATRFIMVVAIVFITCYLP-SVSARLYF 243
P + C I+ SL RQ L + R+K KA R I +V +F+ C++P V+ +Y
Sbjct: 230 TFPFITTVTCYLLIIRSL--RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 287
Query: 244 L-WTVPSSACDPSVHGAL--HITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK 300
L + ++C AL IT T +N LDP++Y+F + F L +C + K
Sbjct: 288 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNL-LCGKRLK 346
Query: 301 QPGHSKTQRPEEMPIS 316
P S + E +S
Sbjct: 347 GPPPSFEGKTNESSLS 362
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 122 bits (305), Expect = 6e-28
Identities = 86/272 (31%), Positives = 136/272 (50%), Gaps = 15/272 (5%)
Query: 24 VAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAF 83
+ FVLG + N VA+ F +K +T Y+ NLA++D L + LPFR +Y R+W F
Sbjct: 26 MVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRI-FYFTTRNWPF 84
Query: 84 GDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCT-LWAL 142
GD+ C++ + N GSI+FLT ++ DR+ +V+P + T+ T+ A IVCT +W
Sbjct: 85 GDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS-KTLRTKRNAKIVCTGVWLT 143
Query: 143 VILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQL-------EFFMPLGIILFC 195
VI G+ + Q S F W + ++ FF+PL + + C
Sbjct: 144 VIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTC 203
Query: 196 SFKIVWSLRRRQQLARQARMK-KATRFIMVVAIVFITCYLP-SVSARLYFL---WTVPSS 250
S ++ +L + L+R K K + I V I+F C++P +++ LY L T +
Sbjct: 204 SSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNC 263
Query: 251 ACDPSVHGALHITLSFTYMNSMLDPLVYYFSS 282
+ +V ITL N DP+VYYF+S
Sbjct: 264 SVVAAVRTMYPITLCIAVSNCCFDPIVYYFTS 295
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 122 bits (305), Expect = 6e-28
Identities = 86/272 (31%), Positives = 136/272 (50%), Gaps = 15/272 (5%)
Query: 24 VAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAF 83
+ FVLG + N VA+ F +K +T Y+ NLA++D L + LPFR +Y R+W F
Sbjct: 26 MVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRI-FYFTTRNWPF 84
Query: 84 GDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCT-LWAL 142
GD+ C++ + N GSI+FLT ++ DR+ +V+P + T+ T+ A IVCT +W
Sbjct: 85 GDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS-KTLRTKRNAKIVCTGVWLT 143
Query: 143 VILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQL-------EFFMPLGIILFC 195
VI G+ + Q S F W + ++ FF+PL + + C
Sbjct: 144 VIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTC 203
Query: 196 SFKIVWSLRRRQQLARQARMK-KATRFIMVVAIVFITCYLP-SVSARLYFL---WTVPSS 250
S ++ +L + L+R K K + I V I+F C++P +++ LY L T +
Sbjct: 204 SSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNC 263
Query: 251 ACDPSVHGALHITLSFTYMNSMLDPLVYYFSS 282
+ +V ITL N DP+VYYF+S
Sbjct: 264 SVVAAVRTMYPITLCIAVSNCCFDPIVYYFTS 295
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 122 bits (305), Expect = 6e-28
Identities = 86/272 (31%), Positives = 136/272 (50%), Gaps = 15/272 (5%)
Query: 24 VAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAF 83
+ FVLG + N VA+ F +K +T Y+ NLA++D L + LPFR +Y R+W F
Sbjct: 26 MVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRI-FYFTTRNWPF 84
Query: 84 GDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCT-LWAL 142
GD+ C++ + N GSI+FLT ++ DR+ +V+P + T+ T+ A IVCT +W
Sbjct: 85 GDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS-KTLRTKRNAKIVCTGVWLT 143
Query: 143 VILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQL-------EFFMPLGIILFC 195
VI G+ + Q S F W + ++ FF+PL + + C
Sbjct: 144 VIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTC 203
Query: 196 SFKIVWSLRRRQQLARQARMK-KATRFIMVVAIVFITCYLP-SVSARLYFL---WTVPSS 250
S ++ +L + L+R K K + I V I+F C++P +++ LY L T +
Sbjct: 204 SSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNC 263
Query: 251 ACDPSVHGALHITLSFTYMNSMLDPLVYYFSS 282
+ +V ITL N DP+VYYF+S
Sbjct: 264 SVVAAVRTMYPITLCIAVSNCCFDPIVYYFTS 295
>gi|33695097 G protein-coupled receptor 35 [Homo sapiens]
Length = 309
Score = 120 bits (302), Expect = 1e-27
Identities = 90/269 (33%), Positives = 133/269 (49%), Gaps = 21/269 (7%)
Query: 24 VAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAF 83
V VLG L N +AL FC M+ W + +Y+ NLAVAD L+ LPF + LR
Sbjct: 29 VLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPF-VLHSLRDT---- 83
Query: 84 GDIP-CRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCTLWAL 142
D P C++ NR SI +T +A DRY V HP A S R AA + LW L
Sbjct: 84 SDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVL 143
Query: 143 VILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQ-LEFFMPLGIILFCSFKIVW 201
VI V L L +QE S + + ++ + F L F++PL +++FCS K+V
Sbjct: 144 VIGSLVARWL---LGIQEGGFCFRS----TRHNFNSMAFPLLGFYLPLAVVVFCSLKVVT 196
Query: 202 SLRRR--QQLARQARMKKATRFIMVVAIVFITCYLP---SVSARLYFLWTVPSSACDPSV 256
+L +R + + +KA R + +VF+ C+LP ++ RL W + A ++
Sbjct: 197 ALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN--ACALLETI 254
Query: 257 HGALHITLSFTYMNSMLDPLVYYFSSPSF 285
AL+IT + N LD + YY+ + F
Sbjct: 255 RRALYITSKLSDANCCLDAICYYYMAKEF 283
>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
Length = 337
Score = 115 bits (288), Expect = 6e-26
Identities = 85/297 (28%), Positives = 137/297 (46%), Gaps = 15/297 (5%)
Query: 3 NGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFC--FHMKTWKPSTVYLFNLAVA 60
+ +C D +QV L + V+G GNG L +H K+ VY+ NLAVA
Sbjct: 11 SATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKS--AFQVYMINLAVA 68
Query: 61 DFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHP 120
D L + LP R YY+ + W FGD CR+ + L +N SI F+T ++ R +V P
Sbjct: 69 DLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFP 128
Query: 121 HHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIM 180
+N ++ + A + +W VIL + L+ ++ C ++ H ++
Sbjct: 129 VQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLV 188
Query: 181 FQ-----LEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLP 235
+ F +P II+ C I+ +L ++ + KKA IMVV F+ ++P
Sbjct: 189 LHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMP 248
Query: 236 ---SVSARLYFLWTVPSSACDP--SVHGALHITLSFTYMNSMLDPLVYYFSSPSFPK 287
+ L+FL + CD + ++ ITLS N DPL+Y+FS +F K
Sbjct: 249 YHIQRTIHLHFLHN-ETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRK 304
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 115 bits (287), Expect = 8e-26
Identities = 85/285 (29%), Positives = 137/285 (48%), Gaps = 22/285 (7%)
Query: 27 VLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAFGDI 86
++G +GN + + + K + +YL NLAVAD L M+ +PF RHW FG +
Sbjct: 59 LVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASS-AALRHWPFGSV 117
Query: 87 PCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCTLWALVILG 146
CR L +N S+ LTV++ DRY VVHP A VA I +W +L
Sbjct: 118 LCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLV 177
Query: 147 T--VYLLLENHLCVQETAVSCESFIMESANGWHDIM----FQLEFFMPLGIILFCSFKIV 200
T + + + AV+C + W + F L F +P+ I C IV
Sbjct: 178 TLPIAIFADTRPARGGQAVACN--LQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIV 235
Query: 201 WSLR----RRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYFLWTVPSSACDPSV 256
+R R R+ KK TR +++V +VF+ C++P +L L+ ++ D +V
Sbjct: 236 GKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFV---TSLDATV 292
Query: 257 HGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNK---LKICSLK 298
+ H++L +Y NS +P++Y F S +F +F+ + L+ C L+
Sbjct: 293 N---HVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLE 334
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 113 bits (283), Expect = 2e-25
Identities = 80/298 (26%), Positives = 141/298 (47%), Gaps = 22/298 (7%)
Query: 10 EGDTISQVMPPLLIVAFV------LGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFL 63
+ T+S+ ++++F+ +G GN + + + K + +Y+ NLA+AD L
Sbjct: 47 QNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADEL 106
Query: 64 LMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHA 123
LM+ +PF L R HW FG + CR+ L A+N SI LTV++ DRY VVHP A
Sbjct: 107 LMLSVPFLVTSTLLR-HWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKA 165
Query: 124 VNTISTRVAAGIVCTLWALVILGTVYLLLENHLCV-QETAVSCESFIMESANGWHD---- 178
VA + +W L +L + +++ + + V+C + E A W
Sbjct: 166 ARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVL 225
Query: 179 IMFQLEFFMPLGIILFCSFKIVWSLRRRQQLA----RQARMKKATRFIMVVAIVFITCYL 234
F + F +P+G I C I+ +R A R+ +K T +M+V +VF+ C++
Sbjct: 226 YTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWM 285
Query: 235 PSVSARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKL 292
P +L ++ A +++ Y NS +P++Y F S +F + + ++
Sbjct: 286 PFYVVQLVNVFAEQDDAT------VSQLSVILGYANSCANPILYGFLSDNFKRSFQRI 337
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 113 bits (283), Expect = 2e-25
Identities = 86/299 (28%), Positives = 139/299 (46%), Gaps = 21/299 (7%)
Query: 13 TISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRT 72
T + V+ + V ++G GN + + + K + +Y+ NLA+AD L M+ LPF
Sbjct: 41 TSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLA 100
Query: 73 DYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVA 132
+ HW FG CRV + +N+ SI LTV++ DRY VVHP + R A
Sbjct: 101 -MQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTA 159
Query: 133 AGIVCTLWALVILGTVYLLLENHL-CVQETAVSCESFIMESANGWHD----IMFQLEFFM 187
I +W + +L + +++ L Q SC + W+ F L F +
Sbjct: 160 KMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLV 219
Query: 188 PLGIILFCSFKIVWSLR----RRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYF 243
PL II C I+ ++ R R+ KK TR + +V VFI C+LP ++
Sbjct: 220 PLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLP------FY 273
Query: 244 LWTVPSSAC----DPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLK 298
++ V S + P++ G + TY NS +P++Y F S +F K + + +C +K
Sbjct: 274 IFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNV-LCLVK 331
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 112 bits (280), Expect = 5e-25
Identities = 75/297 (25%), Positives = 136/297 (45%), Gaps = 14/297 (4%)
Query: 9 IEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICL 68
+ G + +P + + FV+G NG+AL F F K P+ +Y+ NLA+AD L +I
Sbjct: 69 LTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWF 128
Query: 69 PFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTIS 128
P + Y++ +W +G+ C V + N SI+F+T ++ RY+ +V+P +
Sbjct: 129 PLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP-MGHSRKK 187
Query: 129 TRVAAGIVCTLWALVILGTV--YLLLENHLCVQETAVSCESFIMESANGWHDIMFQLEFF 186
+A GI +W L++L T+ Y++ + +C + E MF
Sbjct: 188 ANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQL--LVGDMFNYFLS 245
Query: 187 MPLGIILFCSFKIVWSLRRRQQLARQARM--------KKATRFIMVVAIVFITCYLPSVS 238
+ +G+ LF +F + ++ R + M K+A + I+ V +++ C+ PS
Sbjct: 246 LAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNL 305
Query: 239 ARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKIC 295
+ + + S V+ + L + +NS +DP VYYF S F +C
Sbjct: 306 LLVVHYFLIKSQG-QSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLC 361
>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 112 bits (279), Expect = 6e-25
Identities = 87/302 (28%), Positives = 130/302 (43%), Gaps = 14/302 (4%)
Query: 4 GSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFL 63
G CR D ++P V V G N VAL F +KTW ST Y+F+LAV+D L
Sbjct: 22 GYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDAL 81
Query: 64 LMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHA 123
LP YY R HW F + C++ F N SI+FLT ++ R V+ P +
Sbjct: 82 YAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRS 141
Query: 124 VNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESF----IMESANGWHDI 179
+ R A + +W LV+ +L + V+C + + +
Sbjct: 142 LRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSV 201
Query: 180 MFQLEFFMPLGIILFCSFKIVWSLRRRQQ-----LARQARMKKATRFIMVVAIVFITCYL 234
M L F +P +IL C + L + L R R K+ R I VV VF C+L
Sbjct: 202 MLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKR--KSVRTIAVVLAVFALCFL 259
Query: 235 P-SVSARLYFLWTVPSSACDP--SVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNK 291
P V+ LY+ + +C +++ A +T NS LDP++Y+ + +F
Sbjct: 260 PFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARD 319
Query: 292 LK 293
K
Sbjct: 320 AK 321
>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 112 bits (279), Expect = 6e-25
Identities = 87/302 (28%), Positives = 130/302 (43%), Gaps = 14/302 (4%)
Query: 4 GSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFL 63
G CR D ++P V V G N VAL F +KTW ST Y+F+LAV+D L
Sbjct: 22 GYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDAL 81
Query: 64 LMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHA 123
LP YY R HW F + C++ F N SI+FLT ++ R V+ P +
Sbjct: 82 YAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRS 141
Query: 124 VNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESF----IMESANGWHDI 179
+ R A + +W LV+ +L + V+C + + +
Sbjct: 142 LRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSV 201
Query: 180 MFQLEFFMPLGIILFCSFKIVWSLRRRQQ-----LARQARMKKATRFIMVVAIVFITCYL 234
M L F +P +IL C + L + L R R K+ R I VV VF C+L
Sbjct: 202 MLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKR--KSVRTIAVVLAVFALCFL 259
Query: 235 P-SVSARLYFLWTVPSSACDP--SVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNK 291
P V+ LY+ + +C +++ A +T NS LDP++Y+ + +F
Sbjct: 260 PFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARD 319
Query: 292 LK 293
K
Sbjct: 320 AK 321
>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 112 bits (279), Expect = 6e-25
Identities = 87/302 (28%), Positives = 130/302 (43%), Gaps = 14/302 (4%)
Query: 4 GSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFL 63
G CR D ++P V V G N VAL F +KTW ST Y+F+LAV+D L
Sbjct: 22 GYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDAL 81
Query: 64 LMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHA 123
LP YY R HW F + C++ F N SI+FLT ++ R V+ P +
Sbjct: 82 YAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRS 141
Query: 124 VNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESF----IMESANGWHDI 179
+ R A + +W LV+ +L + V+C + + +
Sbjct: 142 LRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSV 201
Query: 180 MFQLEFFMPLGIILFCSFKIVWSLRRRQQ-----LARQARMKKATRFIMVVAIVFITCYL 234
M L F +P +IL C + L + L R R K+ R I VV VF C+L
Sbjct: 202 MLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKR--KSVRTIAVVLAVFALCFL 259
Query: 235 P-SVSARLYFLWTVPSSACDP--SVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNK 291
P V+ LY+ + +C +++ A +T NS LDP++Y+ + +F
Sbjct: 260 PFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARD 319
Query: 292 LK 293
K
Sbjct: 320 AK 321
>gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 110 bits (276), Expect = 1e-24
Identities = 86/288 (29%), Positives = 129/288 (44%), Gaps = 32/288 (11%)
Query: 21 LLIVAFVL--GALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRR 78
L++ + VL G N +AL F ++ +VY+ NLA +D L + LP R YY
Sbjct: 26 LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALH 85
Query: 79 RHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCT 138
HW F D+ C+ MN GS +FL ++ DRY +VHP + RVA +
Sbjct: 86 -HWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLG 144
Query: 139 LWALVILGTV------------YLLLENHLCVQETAVSCESFIMESANG----WHDIMFQ 182
+WAL+++ V Y LE LC ESF E G +
Sbjct: 145 VWALILVFAVPAARVHRPSRCRYRDLEVRLCF-------ESFSDELWKGRLLPLVLLAEA 197
Query: 183 LEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLP-----SV 237
L F +PL +++ S ++ W+L R Q R +K R ++ ++F+ C++P +V
Sbjct: 198 LGFLLPLAAVVYSSGRVFWTLARPDATQSQ-RRRKTVRLLLANLVIFLLCFVPYNSTLAV 256
Query: 238 SARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSF 285
L S V G L + + N +LDPLVYYFS+ F
Sbjct: 257 YGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGF 304
>gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 110 bits (276), Expect = 1e-24
Identities = 86/288 (29%), Positives = 129/288 (44%), Gaps = 32/288 (11%)
Query: 21 LLIVAFVL--GALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRR 78
L++ + VL G N +AL F ++ +VY+ NLA +D L + LP R YY
Sbjct: 26 LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALH 85
Query: 79 RHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCT 138
HW F D+ C+ MN GS +FL ++ DRY +VHP + RVA +
Sbjct: 86 -HWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLG 144
Query: 139 LWALVILGTV------------YLLLENHLCVQETAVSCESFIMESANG----WHDIMFQ 182
+WAL+++ V Y LE LC ESF E G +
Sbjct: 145 VWALILVFAVPAARVHRPSRCRYRDLEVRLCF-------ESFSDELWKGRLLPLVLLAEA 197
Query: 183 LEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLP-----SV 237
L F +PL +++ S ++ W+L R Q R +K R ++ ++F+ C++P +V
Sbjct: 198 LGFLLPLAAVVYSSGRVFWTLARPDATQSQ-RRRKTVRLLLANLVIFLLCFVPYNSTLAV 256
Query: 238 SARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSF 285
L S V G L + + N +LDPLVYYFS+ F
Sbjct: 257 YGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGF 304
>gi|4557359 bradykinin receptor B2 [Homo sapiens]
Length = 391
Score = 110 bits (274), Expect = 2e-24
Identities = 94/294 (31%), Positives = 133/294 (45%), Gaps = 28/294 (9%)
Query: 14 ISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTD 73
++ + PP L V FVL L N L FC H + + +YL NLA AD +L LPF
Sbjct: 56 LNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAI 115
Query: 74 YYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAA 133
W FG+ CRV ++MN SI FL +V+ DRY + V T+S
Sbjct: 116 TISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLAL------VKTMSMGRMR 169
Query: 134 GI-VCTLWALVILGTVYLLLENHLC-------------VQETAVSCESFIMESANGWHDI 179
G+ L++LVI G LL L V +S S I E +
Sbjct: 170 GVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNM--L 227
Query: 180 MFQLEFFMPLGIILFCSFKIVWSLRRR--QQLARQARMKKATRFIMVVAIVFITCYLP-S 236
+ + F +PL +I FC+ +I+ LR Q+ ++AT ++VV ++FI C+LP
Sbjct: 228 LNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQ 287
Query: 237 VSARLYFLWT--VPSSACDPSVHGALHITLSF-TYMNSMLDPLVYYFSSPSFPK 287
+S L L + SS D + + SF Y NS L+PLVY F K
Sbjct: 288 ISTFLDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRK 341
>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 110 bits (274), Expect = 2e-24
Identities = 78/301 (25%), Positives = 137/301 (45%), Gaps = 12/301 (3%)
Query: 3 NGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADF 62
N + C ++ +S V+ V F++G +GN +AL F + +YL N+A+AD
Sbjct: 42 NVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADL 101
Query: 63 LLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHH 122
LL+ CLPFR Y++ + W G I C+V MN SI+ L ++ DRY K+
Sbjct: 102 LLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQ 161
Query: 123 AVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQ 182
I+T+ + + C +W L + G + +++ + C + + N + +F
Sbjct: 162 QRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHY-RDKHNAKGEAIFN 220
Query: 183 ----LEFFMPLGIILFCSFKIVWSL----RRRQQLARQARMKKATRFIMVVAIVFITCYL 234
+ F++ +I+ KI +L +RR + + R +V I+F C++
Sbjct: 221 FILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFV 280
Query: 235 PSVSARLYFL---WTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNK 291
P + R ++ V S VH I L + NS LDP++Y+ S + K +
Sbjct: 281 PYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQ 340
Query: 292 L 292
L
Sbjct: 341 L 341
>gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
sapiens]
Length = 337
Score = 110 bits (274), Expect = 2e-24
Identities = 71/279 (25%), Positives = 127/279 (45%), Gaps = 16/279 (5%)
Query: 18 MPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLR 77
+P + + F++G GN V + + F M+ WK ST+ + NLA D L + LPF YY
Sbjct: 36 LPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYAS 95
Query: 78 RRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVC 137
+W FGD C+ F+ N SI+FLT + RY ++HP + TR A
Sbjct: 96 GENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACA 155
Query: 138 TLWALVILGTV---YLLLENHLCVQETAVSCESFIMESANGWHD-IMFQLEFFMPLGIIL 193
+W + ++ + +L+ + + + S + W++ I+ F +PL I+
Sbjct: 156 VVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVT 215
Query: 194 FCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLP-------SVSARLYFLWT 246
C I+ +L Q +KA R +++ + F C+LP + +RL +
Sbjct: 216 LCYTTIIHTLTHGLQ-TDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLSI-- 272
Query: 247 VPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSF 285
S + + +H A ++ +N+ + L+Y S +F
Sbjct: 273 --SCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNF 309
>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 110 bits (274), Expect = 2e-24
Identities = 78/301 (25%), Positives = 137/301 (45%), Gaps = 12/301 (3%)
Query: 3 NGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADF 62
N + C ++ +S V+ V F++G +GN +AL F + +YL N+A+AD
Sbjct: 42 NVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADL 101
Query: 63 LLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHH 122
LL+ CLPFR Y++ + W G I C+V MN SI+ L ++ DRY K+
Sbjct: 102 LLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQ 161
Query: 123 AVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQ 182
I+T+ + + C +W L + G + +++ + C + + N + +F
Sbjct: 162 QRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHY-RDKHNAKGEAIFN 220
Query: 183 ----LEFFMPLGIILFCSFKIVWSL----RRRQQLARQARMKKATRFIMVVAIVFITCYL 234
+ F++ +I+ KI +L +RR + + R +V I+F C++
Sbjct: 221 FILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFV 280
Query: 235 PSVSARLYFL---WTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNK 291
P + R ++ V S VH I L + NS LDP++Y+ S + K +
Sbjct: 281 PYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQ 340
Query: 292 L 292
L
Sbjct: 341 L 341
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.140 0.460
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,038,112
Number of Sequences: 37866
Number of extensions: 543000
Number of successful extensions: 2725
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 295
Number of HSP's successfully gapped in prelim test: 248
Number of HSP's that attempted gapping in prelim test: 1778
Number of HSP's gapped (non-prelim): 636
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.