Search of human proteins with 9966791

Search of human proteins with 9966791

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9966791 fascin 3 [Homo sapiens]
         (498 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9966791 fascin 3 [Homo sapiens]                                   1058   0.0  
gi|4507115 fascin 1 [Homo sapiens]                                    181   1e-45
gi|6912626 fascin 2 isoform 1 [Homo sapiens]                          171   2e-42
gi|116295251 fascin 2 isoform 2 [Homo sapiens]                        162   7e-40
gi|4758404 FSHD region gene 1 [Homo sapiens]                           34   0.27 
gi|7657307 LIM domains containing 1 [Homo sapiens]                     32   1.7  
gi|154736713 KDEL receptor 2 isoform 2 [Homo sapiens]                  32   1.7  
gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]         30   3.9  
gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]         30   3.9  
gi|239758061 PREDICTED: similar to hCG1992776 [Homo sapiens]           30   5.1  
gi|239747887 PREDICTED: hypothetical protein XP_002346465 [Homo ...    30   5.1  
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s...    30   6.6  
gi|118572606 hemicentin 1 [Homo sapiens]                               29   8.7  

>gi|9966791 fascin 3 [Homo sapiens]
          Length = 498

 Score = 1058 bits (2735), Expect = 0.0
 Identities = 498/498 (100%), Positives = 498/498 (100%)

Query: 1   MDETEWIHRHPKAEDLRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHET 60
           MDETEWIHRHPKAEDLRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHET
Sbjct: 1   MDETEWIHRHPKAEDLRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHET 60

Query: 61  QAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNG 120
           QAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNG
Sbjct: 61  QAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNG 120

Query: 121 KDVFCTSHVLSAYHMWTPRPALHVHVILYSPIHRCYARADPTMGRIWVDAAVPCLEECGF 180
           KDVFCTSHVLSAYHMWTPRPALHVHVILYSPIHRCYARADPTMGRIWVDAAVPCLEECGF
Sbjct: 121 KDVFCTSHVLSAYHMWTPRPALHVHVILYSPIHRCYARADPTMGRIWVDAAVPCLEECGF 180

Query: 181 LLHFRDGCYHLETSTHHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGT 240
           LLHFRDGCYHLETSTHHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGT
Sbjct: 181 LLHFRDGCYHLETSTHHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGT 240

Query: 241 HLLLGMGCNPMRGEEWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFE 300
           HLLLGMGCNPMRGEEWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFE
Sbjct: 241 HLLLGMGCNPMRGEEWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFE 300

Query: 301 CDSESPTVQLRSANGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGI 360
           CDSESPTVQLRSANGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGI
Sbjct: 301 CDSESPTVQLRSANGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGI 360

Query: 361 APNSLLMANVILPGPNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLL 420
           APNSLLMANVILPGPNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLL
Sbjct: 361 APNSLLMANVILPGPNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLL 420

Query: 421 PCRPGIYHFQAQGGSFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAPNGFYMRADQS 480
           PCRPGIYHFQAQGGSFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAPNGFYMRADQS
Sbjct: 421 PCRPGIYHFQAQGGSFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAPNGFYMRADQS 480

Query: 481 GTLLADSEDITRECIWEF 498
           GTLLADSEDITRECIWEF
Sbjct: 481 GTLLADSEDITRECIWEF 498


>gi|4507115 fascin 1 [Homo sapiens]
          Length = 493

 Score =  181 bits (459), Expect = 1e-45
 Identities = 133/489 (27%), Positives = 212/489 (43%), Gaps = 5/489 (1%)

Query: 12  KAEDLRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHETQAVVRLKSVQG 71
           +A  ++ GLI+    YLT EA    V A+A SL ++Q W +    +    A V L+S  G
Sbjct: 8   EAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLG 67

Query: 72  LYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNGKDVFCTSHVLS 131
            YL  + DG V   R        FL+  H + +W+LQ     RY       + C +  +S
Sbjct: 68  RYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQTVS 127

Query: 132 AYHMWTPRPALHVHVILYSPIHRCYARADP-TMGRIWVDAAVPCLEECGFLLHFRDGCYH 190
               W+   A+H  V +YS   + YA         I VD  VP   +    L F+D  Y 
Sbjct: 128 PAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQRYS 187

Query: 191 LETSTHHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGTHLLLGMG-CN 249
           ++T+ H FL H  RL ++P   T + ++ R  G VA  D EG  L P G    L  G   
Sbjct: 188 VQTADHRFLRHDGRLVARPEPATGYTLEFR-SGKVAFRDCEGRYLAPSGPSGTLKAGKAT 246

Query: 250 PMRGEEWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFECDSESPTVQ 309
            +  +E F L+     V L++   R +S     ++ A  +       FQ E D ++    
Sbjct: 247 KVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCA 306

Query: 310 LRSANGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMAN 369
            R+  G Y +      V +      +  +F + W   RI L++  G+F+    N  L A+
Sbjct: 307 FRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKNGQLAAS 366

Query: 370 VILPGPNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLLPCRPGIYHF 429
           V   G +E F +   NR  +V RG +G++G       +  N+   D +  L    G Y+ 
Sbjct: 367 VETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYD-VFQLEFNDGAYNI 425

Query: 430 QAQGGSFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAPNGFYMRADQSGTLLADSED 489
           +   G +W++ S       G   ++F  E    N + +    G Y++ D +G L A +E 
Sbjct: 426 KDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKV-GGRYLKGDHAGVLKASAET 484

Query: 490 ITRECIWEF 498
           +    +WE+
Sbjct: 485 VDPASLWEY 493


>gi|6912626 fascin 2 isoform 1 [Homo sapiens]
          Length = 492

 Score =  171 bits (432), Expect = 2e-42
 Identities = 136/484 (28%), Positives = 209/484 (43%), Gaps = 4/484 (0%)

Query: 16  LRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHETQAVVRLKSVQGLYLL 75
           ++ GL++    YLT E+    V A+A SL R+QTW +L  +  +  AV+   S  G YL 
Sbjct: 12  IQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTW-VLEPDPGQGTAVLLRSSHLGRYLS 70

Query: 76  CECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNGKDVFCTSHVLSAYHM 135
            E DG V     +      FL+    + +W L+    GR+       + C +  +S   +
Sbjct: 71  AEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAEL 130

Query: 136 WTPRPALHVHVILYSPIHRCYARADPTMGRIWVDAAVPCLEECGFLLHFRDGCYHLETST 195
           WT   A+H    L S   R Y    P    +  D   P   +    L FR   Y L++  
Sbjct: 131 WTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCD 190

Query: 196 HHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGTHLLLGMGCNPMRG-E 254
             +L    RL  +P  +  + ++ + G L A  D +G  L P G    L  G N   G +
Sbjct: 191 SRYLRSDGRLVWEPEPRACYTLEFKAGKL-AFKDCDGHYLAPVGPAGTLKAGRNTRPGKD 249

Query: 255 EWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFECDSESPTVQLRSAN 314
           E F L+     V L +   R++SV     V A  +       F  + D E+      S+ 
Sbjct: 250 ELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSST 309

Query: 315 GYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMANVILPG 374
           G Y +   H  + A    + ++T F M W   R+ L++  GR++ +  N  L A     G
Sbjct: 310 GGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVG 369

Query: 375 PNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLLPCRPGIYHFQAQGG 434
            +EEF +   NR  LVLRG  G+V    G + +  N+   D  H L    G Y  + + G
Sbjct: 370 KDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFH-LSFSDGAYRIRGRDG 428

Query: 435 SFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAPNGFYMRADQSGTLLADSEDITREC 494
            FW   S G+    G+ A +F  E +    L + A +G Y+R   SG L AD++      
Sbjct: 429 GFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTA 488

Query: 495 IWEF 498
           +WE+
Sbjct: 489 LWEY 492


>gi|116295251 fascin 2 isoform 2 [Homo sapiens]
          Length = 516

 Score =  162 bits (410), Expect = 7e-40
 Identities = 137/508 (26%), Positives = 211/508 (41%), Gaps = 28/508 (5%)

Query: 16  LRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHETQAVVRLKSVQGLYLL 75
           ++ GL++    YLT E+    V A+A SL R+QTW +L  +  +  AV+   S  G YL 
Sbjct: 12  IQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTW-VLEPDPGQGTAVLLRSSHLGRYLS 70

Query: 76  CECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNGKDVFCTSHVLSAYHM 135
            E DG V     +      FL+    + +W L+    GR+       + C +  +S   +
Sbjct: 71  AEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAEL 130

Query: 136 WTPRPALHVHVILYSPIHRCYARADPTMGRIWVDAAVPCLEECGFLLHFRDGCYHLETST 195
           WT   A+H    L S   R Y    P    +  D   P   +    L FR   Y L++  
Sbjct: 131 WTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCD 190

Query: 196 HHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGTHLLLGMGCNPMRG-E 254
             +L    RL  +P  +  + ++ + G L A  D +G  L P G    L  G N   G +
Sbjct: 191 SRYLRSDGRLVWEPEPRACYTLEFKAGKL-AFKDCDGHYLAPVGPAGTLKAGRNTRPGKD 249

Query: 255 EWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFECDSESPTVQLRSAN 314
           E F L+     V L +   R++SV     V A  +       F  + D E+      S+ 
Sbjct: 250 ELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSST 309

Query: 315 GYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMA------ 368
           G Y +   H  + A    + ++T F M W   R+ L++  GR++ +  N  L A      
Sbjct: 310 GGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVG 369

Query: 369 ------------------NVILPGPNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCN 410
                              +  PG +EEF +   NR  LVLRG  G+V    G + +  N
Sbjct: 370 PPPRPAWTGKVAGGAAQQTLSPPGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTN 429

Query: 411 QDQPDRIHLLPCRPGIYHFQAQGGSFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAP 470
           +   D  H L    G Y  + + G FW   S G+    G+ A +F  E +    L + A 
Sbjct: 430 RSVYDVFH-LSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRAR 488

Query: 471 NGFYMRADQSGTLLADSEDITRECIWEF 498
           +G Y+R   SG L AD++      +WE+
Sbjct: 489 SGKYLRGGASGLLRADADAPAGTALWEY 516


>gi|4758404 FSHD region gene 1 [Homo sapiens]
          Length = 258

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 314 NGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMANVILP 373
           NG +     H+ V  D  P   + F  +  +  RI L+S  G++LGI  + L++      
Sbjct: 75  NGLFTLGAPHKEV--DEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAI 132

Query: 374 GPNEEFGILFANRSFLVLRGRYGYVGSSSGHDL 406
           GP E++  +F N    +L     ++  +   D+
Sbjct: 133 GPREQWEPVFQNGKMALLASNSCFIRCNEAGDI 165


>gi|7657307 LIM domains containing 1 [Homo sapiens]
          Length = 676

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 20/43 (46%), Positives = 23/43 (53%), Gaps = 3/43 (6%)

Query: 176 EECGFLLHFRDG--CYHLETSTHHFLSHVDRLFSQPSSQTAFH 216
           E+CG  L+  DG  CY LE        HV RL  +PSS TA H
Sbjct: 631 EDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKRPSS-TALH 672


>gi|154736713 KDEL receptor 2 isoform 2 [Homo sapiens]
          Length = 186

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 16/53 (30%), Positives = 24/53 (45%)

Query: 293 RMSLFQFECDSESPTVQLRSANGYYLSQRRHRAVMADGHPLESDTFFRMHWNC 345
           R S+ Q +C   SP   L+ A   +L Q+RH+ +  +   L S       W C
Sbjct: 122 RSSVCQHKCQRPSPASVLQGARTEFLPQQRHKMLDTENQKLNSFVADSHQWLC 174


>gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]
          Length = 567

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 3/80 (3%)

Query: 46  RRQTWEILVSNEHETQAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKW 105
           RR+  + L + +   +    +K+  G    C       YG   T HH C+LL       W
Sbjct: 69  RREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYG---TWHHRCWLLGRLPEPNW 125

Query: 106 TLQCLISGRYLESNGKDVFC 125
           T +  +  R+LE + ++  C
Sbjct: 126 TRELELCARFLEVDERNFHC 145


>gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]
          Length = 567

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 3/80 (3%)

Query: 46  RRQTWEILVSNEHETQAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKW 105
           RR+  + L + +   +    +K+  G    C       YG   T HH C+LL       W
Sbjct: 69  RREVLQQLETQKSPEELAALVKAELGFLESCLRVNPKSYG---TWHHRCWLLGRLPEPNW 125

Query: 106 TLQCLISGRYLESNGKDVFC 125
           T +  +  R+LE + ++  C
Sbjct: 126 TRELELCARFLEVDERNFHC 145


>gi|239758061 PREDICTED: similar to hCG1992776 [Homo sapiens]
          Length = 206

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 314 NGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMANVILP 373
           NG +     H+ V  D  P   + F  +  +  RI L+S  G++LGI  + L++      
Sbjct: 34  NGLFTLGAPHKEV--DEGPSPPEQFSAVKLSDSRITLKSGYGKYLGINSDELVVGRSDAI 91

Query: 374 GPNEEFGILF 383
           GP E++  +F
Sbjct: 92  GPREQWEPVF 101


>gi|239747887 PREDICTED: hypothetical protein XP_002346465 [Homo
           sapiens]
          Length = 206

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 314 NGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMANVILP 373
           NG +     H+ V  D  P   + F  +  +  RI L+S  G++LGI  + L++      
Sbjct: 34  NGLFTLGAPHKEV--DEGPSPPEQFSAVKLSDSRITLKSGYGKYLGINSDELVVGRSDAI 91

Query: 374 GPNEEFGILF 383
           GP E++  +F
Sbjct: 92  GPREQWEPVF 101


>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
            sapiens]
          Length = 2302

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 283  EVRAASERLNRMSLFQFECDSESPTVQLRSANGYYLSQRRHR----AVMADGHPL 333
            E  A S    + +  +   D +  TVQ++   G  L+ ++H+     VM DGHPL
Sbjct: 1949 EASAVSTAAAQFTKLRRGMDEKEFTVQIKDEEGLKLTFQKHKLMANGVMGDGHPL 2003


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 8/67 (11%)

Query: 309  QLRSANGYYLSQRRHRAVM---ADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSL 365
            ++RS  G+Y      +A++   ADG P  +     ++W    ++L +  G++       L
Sbjct: 4170 RIRSTEGHYTVNENSQAILPCVADGIPTPA-----INWKKDNVLLANLLGKYTAEPYGEL 4224

Query: 366  LMANVIL 372
            ++ NV+L
Sbjct: 4225 ILENVVL 4231


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,051,560
Number of Sequences: 37866
Number of extensions: 980541
Number of successful extensions: 2007
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1973
Number of HSP's gapped (non-prelim): 17
length of query: 498
length of database: 18,247,518
effective HSP length: 106
effective length of query: 392
effective length of database: 14,233,722
effective search space: 5579619024
effective search space used: 5579619024
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.