Guide to the Human Genome
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Search of human proteins with 9945439

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9945439 septin 5 [Homo sapiens]
         (369 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9945439 septin 5 [Homo sapiens]                                    751   0.0  
gi|4758942 septin 4 isoform 1 [Homo sapiens]                          576   e-164
gi|17986247 septin 4 isoform 3 [Homo sapiens]                         576   e-164
gi|16604248 septin 1 [Homo sapiens]                                   478   e-135
gi|56549640 septin 2 [Homo sapiens]                                   428   e-120
gi|56549638 septin 2 [Homo sapiens]                                   428   e-120
gi|56549636 septin 2 [Homo sapiens]                                   428   e-120
gi|4758158 septin 2 [Homo sapiens]                                    428   e-120
gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]          380   e-106
gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]          380   e-106
gi|156602655 septin 3 isoform A [Homo sapiens]                        305   4e-83
gi|156602653 septin 3 isoform B [Homo sapiens]                        302   3e-82
gi|164698504 septin 9 isoform f [Homo sapiens]                        302   4e-82
gi|164698502 septin 9 isoform d [Homo sapiens]                        302   4e-82
gi|164698500 septin 9 isoform e [Homo sapiens]                        302   4e-82
gi|164698498 septin 9 isoform b [Homo sapiens]                        302   4e-82
gi|164698496 septin 9 isoform e [Homo sapiens]                        302   4e-82
gi|164698494 septin 9 isoform a [Homo sapiens]                        302   4e-82
gi|116256489 septin 9 isoform c [Homo sapiens]                        302   4e-82
gi|17986245 septin 4 isoform 2 [Homo sapiens]                         288   4e-78
gi|226492421 septin 12 isoform 2 [Homo sapiens]                       263   2e-70
gi|149363638 septin 8 isoform c [Homo sapiens]                        262   4e-70
gi|149363689 septin 8 isoform a [Homo sapiens]                        262   4e-70
gi|149363661 septin 8 isoform b [Homo sapiens]                        262   4e-70
gi|21361478 septin 6 isoform B [Homo sapiens]                         260   1e-69
gi|22035581 septin 6 isoform D [Homo sapiens]                         260   1e-69
gi|22035579 septin 6 isoform A [Homo sapiens]                         260   1e-69
gi|22035577 septin 6 isoform A [Homo sapiens]                         260   1e-69
gi|8922712 septin 11 [Homo sapiens]                                   257   1e-68
gi|30795193 septin 10 isoform 2 [Homo sapiens]                        253   2e-67

>gi|9945439 septin 5 [Homo sapiens]
          Length = 369

 Score =  751 bits (1939), Expect = 0.0
 Identities = 369/369 (100%), Positives = 369/369 (100%)

Query: 1   MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL 60
           MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
Sbjct: 1   MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL 60

Query: 61  VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE 120
           VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE
Sbjct: 61  VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE 120

Query: 121 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE 180
           CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE
Sbjct: 121 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE 180

Query: 181 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE 240
           KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE
Sbjct: 181 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE 240

Query: 241 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC 300
           SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC
Sbjct: 241 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC 300

Query: 301 DVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQ 360
           DVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQ
Sbjct: 301 DVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQ 360

Query: 361 RMKQQMQDQ 369
           RMKQQMQDQ
Sbjct: 361 RMKQQMQDQ 369


>gi|4758942 septin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score =  576 bits (1484), Expect = e-164
 Identities = 280/364 (76%), Positives = 315/364 (86%), Gaps = 10/364 (2%)

Query: 14  PEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDR 73
           P D  + DK+YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLV+SLFLTDLY+DR
Sbjct: 114 PYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDR 173

Query: 74  KLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQF 133
           KLL AEERI QTVEI KH VDIEEKGV+L+LTIVDTPGFGDAVNNTECWKP+ +Y+DQQF
Sbjct: 174 KLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQF 233

Query: 134 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADC 193
           EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRP+DV FMKALH++VNIVP++AKAD 
Sbjct: 234 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADT 293

Query: 194 LVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVV 253
           L P E+   K +IREEI+ FGI +YQFP+CDSDEDEDFK QD+ LKES PFAVIGSNTVV
Sbjct: 294 LTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVV 353

Query: 254 EAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQ 313
           EA+G+RVRGRLYPWGIVEVEN  HCDFVKLR ML+RTHM DLKDVT + HYENYRA CIQ
Sbjct: 354 EARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQ 413

Query: 314 QMT---------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQ 364
            MT         +KLT++S  + PIP +P P  D ETEKLIR KDEELRRMQEML ++++
Sbjct: 414 SMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLIREKDEELRRMQEMLHKIQK 472

Query: 365 QMQD 368
           QM++
Sbjct: 473 QMKE 476


>gi|17986247 septin 4 isoform 3 [Homo sapiens]
          Length = 459

 Score =  576 bits (1484), Expect = e-164
 Identities = 280/364 (76%), Positives = 315/364 (86%), Gaps = 10/364 (2%)

Query: 14  PEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDR 73
           P D  + DK+YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLV+SLFLTDLY+DR
Sbjct: 95  PYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDR 154

Query: 74  KLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQF 133
           KLL AEERI QTVEI KH VDIEEKGV+L+LTIVDTPGFGDAVNNTECWKP+ +Y+DQQF
Sbjct: 155 KLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQF 214

Query: 134 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADC 193
           EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRP+DV FMKALH++VNIVP++AKAD 
Sbjct: 215 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADT 274

Query: 194 LVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVV 253
           L P E+   K +IREEI+ FGI +YQFP+CDSDEDEDFK QD+ LKES PFAVIGSNTVV
Sbjct: 275 LTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVV 334

Query: 254 EAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQ 313
           EA+G+RVRGRLYPWGIVEVEN  HCDFVKLR ML+RTHM DLKDVT + HYENYRA CIQ
Sbjct: 335 EARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQ 394

Query: 314 QMT---------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQ 364
            MT         +KLT++S  + PIP +P P  D ETEKLIR KDEELRRMQEML ++++
Sbjct: 395 SMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLIREKDEELRRMQEMLHKIQK 453

Query: 365 QMQD 368
           QM++
Sbjct: 454 QMKE 457


>gi|16604248 septin 1 [Homo sapiens]
          Length = 367

 Score =  478 bits (1229), Expect = e-135
 Identities = 231/359 (64%), Positives = 291/359 (81%), Gaps = 15/359 (4%)

Query: 20  IDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAE 79
           +DK+YVGFA LPNQ+HRKSVKKGFDFTLMVAGESGLGKSTL++SLFLT+LY+DR++  A 
Sbjct: 1   MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEAS 60

Query: 80  ERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRD 139
            R++QT+ I +  V+IEE GVK+KLT+VDTPGFGD+V+ ++CW P+  ++++QFEQY RD
Sbjct: 61  ARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRD 120

Query: 140 ESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEI 199
           ESGLNRKNIQD+RVHCCLYFISPFG GLRP+DV F++A+HEKVNI+P+I KAD L+P E 
Sbjct: 121 ESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQET 180

Query: 200 RKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQR 259
           + LK++IR+++ +  IH+YQFPECDSDEDEDFK+QD E+KES PFAV+GS  VV   G R
Sbjct: 181 QALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNR 240

Query: 260 -VRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT-- 316
            VRGR Y WG VEVEN  HCDF+ LR ML++TH+ DLK+VT D+ YE YRA C+Q +   
Sbjct: 241 PVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARP 300

Query: 317 --------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQ 367
                   SKL++ S  E P+P+LPL    A+TEKLIR KDEELRRMQEML++M+ QMQ
Sbjct: 301 GARDRASRSKLSRQSATEIPLPMLPL----ADTEKLIREKDEELRRMQEMLEKMQAQMQ 355


>gi|56549640 septin 2 [Homo sapiens]
          Length = 361

 Score =  428 bits (1101), Expect = e-120
 Identities = 209/346 (60%), Positives = 268/346 (77%), Gaps = 16/346 (4%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL++SLFLTDLY +R +  A E+I 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
           +TV+I   TV+IEE+GVKL+LT+VDTPG+GDA+N  +C+K I  Y+D+QFE+Y  DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 144 NRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
           NR++I DNRVHCC YFISPFGHGL+P+DV FMKA+H KVNIVP+IAKAD L   E  +LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
           +RI +EI++  I +Y  P+ +SDEDEDFK+Q R LK S PF+V+GSN ++EAKG++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256

Query: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323
           LYPWG+VEVEN  H DF+KLR MLI THM DL++VT D+HYEN+R+  +++   K+  + 
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314

Query: 324 RMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 369
                         D   ++++  K+ ELRRMQEM+ RM+ QMQ Q
Sbjct: 315 --------------DMNKDQILLEKEAELRRMQEMIARMQAQMQMQ 346


>gi|56549638 septin 2 [Homo sapiens]
          Length = 361

 Score =  428 bits (1101), Expect = e-120
 Identities = 209/346 (60%), Positives = 268/346 (77%), Gaps = 16/346 (4%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL++SLFLTDLY +R +  A E+I 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
           +TV+I   TV+IEE+GVKL+LT+VDTPG+GDA+N  +C+K I  Y+D+QFE+Y  DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 144 NRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
           NR++I DNRVHCC YFISPFGHGL+P+DV FMKA+H KVNIVP+IAKAD L   E  +LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
           +RI +EI++  I +Y  P+ +SDEDEDFK+Q R LK S PF+V+GSN ++EAKG++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256

Query: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323
           LYPWG+VEVEN  H DF+KLR MLI THM DL++VT D+HYEN+R+  +++   K+  + 
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314

Query: 324 RMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 369
                         D   ++++  K+ ELRRMQEM+ RM+ QMQ Q
Sbjct: 315 --------------DMNKDQILLEKEAELRRMQEMIARMQAQMQMQ 346


>gi|56549636 septin 2 [Homo sapiens]
          Length = 361

 Score =  428 bits (1101), Expect = e-120
 Identities = 209/346 (60%), Positives = 268/346 (77%), Gaps = 16/346 (4%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL++SLFLTDLY +R +  A E+I 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
           +TV+I   TV+IEE+GVKL+LT+VDTPG+GDA+N  +C+K I  Y+D+QFE+Y  DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 144 NRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
           NR++I DNRVHCC YFISPFGHGL+P+DV FMKA+H KVNIVP+IAKAD L   E  +LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
           +RI +EI++  I +Y  P+ +SDEDEDFK+Q R LK S PF+V+GSN ++EAKG++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256

Query: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323
           LYPWG+VEVEN  H DF+KLR MLI THM DL++VT D+HYEN+R+  +++   K+  + 
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314

Query: 324 RMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 369
                         D   ++++  K+ ELRRMQEM+ RM+ QMQ Q
Sbjct: 315 --------------DMNKDQILLEKEAELRRMQEMIARMQAQMQMQ 346


>gi|4758158 septin 2 [Homo sapiens]
          Length = 361

 Score =  428 bits (1101), Expect = e-120
 Identities = 209/346 (60%), Positives = 268/346 (77%), Gaps = 16/346 (4%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL++SLFLTDLY +R +  A E+I 
Sbjct: 17  YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
           +TV+I   TV+IEE+GVKL+LT+VDTPG+GDA+N  +C+K I  Y+D+QFE+Y  DESGL
Sbjct: 77  RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136

Query: 144 NRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
           NR++I DNRVHCC YFISPFGHGL+P+DV FMKA+H KVNIVP+IAKAD L   E  +LK
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196

Query: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
           +RI +EI++  I +Y  P+ +SDEDEDFK+Q R LK S PF+V+GSN ++EAKG++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256

Query: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323
           LYPWG+VEVEN  H DF+KLR MLI THM DL++VT D+HYEN+R+  +++   K+  + 
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314

Query: 324 RMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ 369
                         D   ++++  K+ ELRRMQEM+ RM+ QMQ Q
Sbjct: 315 --------------DMNKDQILLEKEAELRRMQEMIARMQAQMQMQ 346


>gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]
          Length = 437

 Score =  380 bits (977), Expect = e-106
 Identities = 187/345 (54%), Positives = 250/345 (72%), Gaps = 5/345 (1%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           YVGFA LPNQV+RKSVK+GF+FTLMV GESGLGKSTL++SLFLTDLY   +      RI 
Sbjct: 30  YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 88

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
           +TV++ +  V I+E GV+L LTIVDTPGFGDAV+N+ CW+P+ DY+D +FE Y   ES +
Sbjct: 89  KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 148

Query: 144 NRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
           NR+ + DNRV CCLYFI+P GHGL+P+D+ FMK LHEKVNI+PLIAKAD L P E ++ K
Sbjct: 149 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 208

Query: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
           ++I +EI +  I +Y+FPE D   DE+  +  +++K+  P AV+GSNT++E  G+RVRGR
Sbjct: 209 KQIMKEIQEHKIKIYEFPETD---DEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGR 265

Query: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323
            YPWG+ EVEN  HCDF  LRNMLIRTHM DLKDVT +VHYENYR+  +  +T     ++
Sbjct: 266 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNN 325

Query: 324 RMESPIPILPLPTPDAE-TEKLIRMKDEELRRMQEMLQRMKQQMQ 367
           + +  +   PL   + E  E + +MK  E+   Q    ++K+++Q
Sbjct: 326 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQ 370


>gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]
          Length = 436

 Score =  380 bits (977), Expect = e-106
 Identities = 187/345 (54%), Positives = 250/345 (72%), Gaps = 5/345 (1%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           YVGFA LPNQV+RKSVK+GF+FTLMV GESGLGKSTL++SLFLTDLY   +      RI 
Sbjct: 29  YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 87

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
           +TV++ +  V I+E GV+L LTIVDTPGFGDAV+N+ CW+P+ DY+D +FE Y   ES +
Sbjct: 88  KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147

Query: 144 NRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
           NR+ + DNRV CCLYFI+P GHGL+P+D+ FMK LHEKVNI+PLIAKAD L P E ++ K
Sbjct: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207

Query: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
           ++I +EI +  I +Y+FPE D   DE+  +  +++K+  P AV+GSNT++E  G+RVRGR
Sbjct: 208 KQIMKEIQEHKIKIYEFPETD---DEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGR 264

Query: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDS 323
            YPWG+ EVEN  HCDF  LRNMLIRTHM DLKDVT +VHYENYR+  +  +T     ++
Sbjct: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNN 324

Query: 324 RMESPIPILPLPTPDAE-TEKLIRMKDEELRRMQEMLQRMKQQMQ 367
           + +  +   PL   + E  E + +MK  E+   Q    ++K+++Q
Sbjct: 325 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQ 369


>gi|156602655 septin 3 isoform A [Homo sapiens]
          Length = 358

 Score =  305 bits (781), Expect = 4e-83
 Identities = 156/339 (46%), Positives = 223/339 (65%), Gaps = 10/339 (2%)

Query: 8   KSKLATPEDKQDIDKQ---YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSL 64
           + K A P     I+     Y+G  T+  Q+ +K++K GFDF +MV G+SGLGKSTLV++L
Sbjct: 22  RPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTL 81

Query: 65  FLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKP 124
           F + + +     + EE+I +TVEI      IEE GVK+KLT++DTPGFGD +NN  CW+P
Sbjct: 82  FKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEP 141

Query: 125 ITDYVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVN 183
           I  Y+++Q+E++ ++E  + R K I D RVHCCLYFISP GH LRP+D+ FMK L + VN
Sbjct: 142 IEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVN 201

Query: 184 IVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDED-EDFKQQDRELKESA 242
           I+P+IAKAD +   E  + K+R+R+E++  GI  Y  P+ + DED ED  + D+  +ES 
Sbjct: 202 IIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFY--PQKEFDEDLEDKTENDKIRQESM 259

Query: 243 PFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDV 302
           PFAV+GS+   +  G+RV GR  PWGI+EVEN  HC+F  LR+ +IRTH+ DLK+VT ++
Sbjct: 260 PFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNI 319

Query: 303 HYENYRAHCIQQMTSKLTQDSRMES---PIPILPLPTPD 338
           HYE YRA  +         +  + +   P+P  P PT +
Sbjct: 320 HYETYRAKRLNDNGGLPPGEGLLGTVLPPVPATPCPTAE 358


>gi|156602653 septin 3 isoform B [Homo sapiens]
          Length = 350

 Score =  302 bits (774), Expect = 3e-82
 Identities = 151/307 (49%), Positives = 212/307 (69%), Gaps = 7/307 (2%)

Query: 8   KSKLATPEDKQDIDKQ---YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSL 64
           + K A P     I+     Y+G  T+  Q+ +K++K GFDF +MV G+SGLGKSTLV++L
Sbjct: 22  RPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTL 81

Query: 65  FLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKP 124
           F + + +     + EE+I +TVEI      IEE GVK+KLT++DTPGFGD +NN  CW+P
Sbjct: 82  FKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEP 141

Query: 125 ITDYVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVN 183
           I  Y+++Q+E++ ++E  + R K I D RVHCCLYFISP GH LRP+D+ FMK L + VN
Sbjct: 142 IEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVN 201

Query: 184 IVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDED-EDFKQQDRELKESA 242
           I+P+IAKAD +   E  + K+R+R+E++  GI  Y  P+ + DED ED  + D+  +ES 
Sbjct: 202 IIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFY--PQKEFDEDLEDKTENDKIRQESM 259

Query: 243 PFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDV 302
           PFAV+GS+   +  G+RV GR  PWGI+EVEN  HC+F  LR+ +IRTH+ DLK+VT ++
Sbjct: 260 PFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNI 319

Query: 303 HYENYRA 309
           HYE YRA
Sbjct: 320 HYETYRA 326


>gi|164698504 septin 9 isoform f [Homo sapiens]
          Length = 335

 Score =  302 bits (773), Expect = 4e-82
 Identities = 146/322 (45%), Positives = 215/322 (66%), Gaps = 3/322 (0%)

Query: 8   KSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLT 67
           K   A+  +K  +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTL+++LF +
Sbjct: 11  KQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 70

Query: 68  DLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD 127
            + +     ++EERI +T+EI   T DIEEKGV++KLT++DTPGFGD +NN  CW+PI  
Sbjct: 71  KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMK 130

Query: 128 YVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVP 186
           +++ Q+E+Y ++E  +NR K I D RVHCCLYFI   GH LRP+D+ FMK L + VNIVP
Sbjct: 131 FINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVP 190

Query: 187 LIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAV 246
           +IAKAD L   E    K+RI  ++   GI VY  P+ + DED + +  + + +E  PFAV
Sbjct: 191 VIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAV 248

Query: 247 IGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYEN 306
           +GS+   +  G+R+ GR   WG +EVEN  HC+F  LR++LIRTHM ++KD+T  +H+E 
Sbjct: 249 VGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEA 308

Query: 307 YRAHCIQQMTSKLTQDSRMESP 328
           YR   + + +S +      + P
Sbjct: 309 YRVKRLNEGSSAMANGMEEKEP 330


>gi|164698502 septin 9 isoform d [Homo sapiens]
          Length = 474

 Score =  302 bits (773), Expect = 4e-82
 Identities = 146/322 (45%), Positives = 215/322 (66%), Gaps = 3/322 (0%)

Query: 8   KSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLT 67
           K   A+  +K  +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTL+++LF +
Sbjct: 150 KQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 209

Query: 68  DLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD 127
            + +     ++EERI +T+EI   T DIEEKGV++KLT++DTPGFGD +NN  CW+PI  
Sbjct: 210 KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMK 269

Query: 128 YVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVP 186
           +++ Q+E+Y ++E  +NR K I D RVHCCLYFI   GH LRP+D+ FMK L + VNIVP
Sbjct: 270 FINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVP 329

Query: 187 LIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAV 246
           +IAKAD L   E    K+RI  ++   GI VY  P+ + DED + +  + + +E  PFAV
Sbjct: 330 VIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAV 387

Query: 247 IGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYEN 306
           +GS+   +  G+R+ GR   WG +EVEN  HC+F  LR++LIRTHM ++KD+T  +H+E 
Sbjct: 388 VGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEA 447

Query: 307 YRAHCIQQMTSKLTQDSRMESP 328
           YR   + + +S +      + P
Sbjct: 448 YRVKRLNEGSSAMANGMEEKEP 469


>gi|164698500 septin 9 isoform e [Homo sapiens]
          Length = 422

 Score =  302 bits (773), Expect = 4e-82
 Identities = 146/322 (45%), Positives = 215/322 (66%), Gaps = 3/322 (0%)

Query: 8   KSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLT 67
           K   A+  +K  +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTL+++LF +
Sbjct: 98  KQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 157

Query: 68  DLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD 127
            + +     ++EERI +T+EI   T DIEEKGV++KLT++DTPGFGD +NN  CW+PI  
Sbjct: 158 KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMK 217

Query: 128 YVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVP 186
           +++ Q+E+Y ++E  +NR K I D RVHCCLYFI   GH LRP+D+ FMK L + VNIVP
Sbjct: 218 FINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVP 277

Query: 187 LIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAV 246
           +IAKAD L   E    K+RI  ++   GI VY  P+ + DED + +  + + +E  PFAV
Sbjct: 278 VIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAV 335

Query: 247 IGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYEN 306
           +GS+   +  G+R+ GR   WG +EVEN  HC+F  LR++LIRTHM ++KD+T  +H+E 
Sbjct: 336 VGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEA 395

Query: 307 YRAHCIQQMTSKLTQDSRMESP 328
           YR   + + +S +      + P
Sbjct: 396 YRVKRLNEGSSAMANGMEEKEP 417


>gi|164698498 septin 9 isoform b [Homo sapiens]
          Length = 579

 Score =  302 bits (773), Expect = 4e-82
 Identities = 146/322 (45%), Positives = 215/322 (66%), Gaps = 3/322 (0%)

Query: 8   KSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLT 67
           K   A+  +K  +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTL+++LF +
Sbjct: 255 KQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 314

Query: 68  DLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD 127
            + +     ++EERI +T+EI   T DIEEKGV++KLT++DTPGFGD +NN  CW+PI  
Sbjct: 315 KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMK 374

Query: 128 YVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVP 186
           +++ Q+E+Y ++E  +NR K I D RVHCCLYFI   GH LRP+D+ FMK L + VNIVP
Sbjct: 375 FINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVP 434

Query: 187 LIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAV 246
           +IAKAD L   E    K+RI  ++   GI VY  P+ + DED + +  + + +E  PFAV
Sbjct: 435 VIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAV 492

Query: 247 IGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYEN 306
           +GS+   +  G+R+ GR   WG +EVEN  HC+F  LR++LIRTHM ++KD+T  +H+E 
Sbjct: 493 VGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEA 552

Query: 307 YRAHCIQQMTSKLTQDSRMESP 328
           YR   + + +S +      + P
Sbjct: 553 YRVKRLNEGSSAMANGMEEKEP 574


>gi|164698496 septin 9 isoform e [Homo sapiens]
          Length = 422

 Score =  302 bits (773), Expect = 4e-82
 Identities = 146/322 (45%), Positives = 215/322 (66%), Gaps = 3/322 (0%)

Query: 8   KSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLT 67
           K   A+  +K  +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTL+++LF +
Sbjct: 98  KQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 157

Query: 68  DLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD 127
            + +     ++EERI +T+EI   T DIEEKGV++KLT++DTPGFGD +NN  CW+PI  
Sbjct: 158 KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMK 217

Query: 128 YVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVP 186
           +++ Q+E+Y ++E  +NR K I D RVHCCLYFI   GH LRP+D+ FMK L + VNIVP
Sbjct: 218 FINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVP 277

Query: 187 LIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAV 246
           +IAKAD L   E    K+RI  ++   GI VY  P+ + DED + +  + + +E  PFAV
Sbjct: 278 VIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAV 335

Query: 247 IGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYEN 306
           +GS+   +  G+R+ GR   WG +EVEN  HC+F  LR++LIRTHM ++KD+T  +H+E 
Sbjct: 336 VGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEA 395

Query: 307 YRAHCIQQMTSKLTQDSRMESP 328
           YR   + + +S +      + P
Sbjct: 396 YRVKRLNEGSSAMANGMEEKEP 417


>gi|164698494 septin 9 isoform a [Homo sapiens]
          Length = 586

 Score =  302 bits (773), Expect = 4e-82
 Identities = 146/322 (45%), Positives = 215/322 (66%), Gaps = 3/322 (0%)

Query: 8   KSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLT 67
           K   A+  +K  +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTL+++LF +
Sbjct: 262 KQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 321

Query: 68  DLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD 127
            + +     ++EERI +T+EI   T DIEEKGV++KLT++DTPGFGD +NN  CW+PI  
Sbjct: 322 KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMK 381

Query: 128 YVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVP 186
           +++ Q+E+Y ++E  +NR K I D RVHCCLYFI   GH LRP+D+ FMK L + VNIVP
Sbjct: 382 FINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVP 441

Query: 187 LIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAV 246
           +IAKAD L   E    K+RI  ++   GI VY  P+ + DED + +  + + +E  PFAV
Sbjct: 442 VIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAV 499

Query: 247 IGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYEN 306
           +GS+   +  G+R+ GR   WG +EVEN  HC+F  LR++LIRTHM ++KD+T  +H+E 
Sbjct: 500 VGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEA 559

Query: 307 YRAHCIQQMTSKLTQDSRMESP 328
           YR   + + +S +      + P
Sbjct: 560 YRVKRLNEGSSAMANGMEEKEP 581


>gi|116256489 septin 9 isoform c [Homo sapiens]
          Length = 568

 Score =  302 bits (773), Expect = 4e-82
 Identities = 146/322 (45%), Positives = 215/322 (66%), Gaps = 3/322 (0%)

Query: 8   KSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLT 67
           K   A+  +K  +D  YVG  ++  Q+ RK++K+GF+F +MV G+SGLGKSTL+++LF +
Sbjct: 244 KQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 303

Query: 68  DLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD 127
            + +     ++EERI +T+EI   T DIEEKGV++KLT++DTPGFGD +NN  CW+PI  
Sbjct: 304 KISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMK 363

Query: 128 YVDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVP 186
           +++ Q+E+Y ++E  +NR K I D RVHCCLYFI   GH LRP+D+ FMK L + VNIVP
Sbjct: 364 FINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVP 423

Query: 187 LIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAV 246
           +IAKAD L   E    K+RI  ++   GI VY  P+ + DED + +  + + +E  PFAV
Sbjct: 424 VIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAV 481

Query: 247 IGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYEN 306
           +GS+   +  G+R+ GR   WG +EVEN  HC+F  LR++LIRTHM ++KD+T  +H+E 
Sbjct: 482 VGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEA 541

Query: 307 YRAHCIQQMTSKLTQDSRMESP 328
           YR   + + +S +      + P
Sbjct: 542 YRVKRLNEGSSAMANGMEEKEP 563


>gi|17986245 septin 4 isoform 2 [Homo sapiens]
          Length = 274

 Score =  288 bits (738), Expect = 4e-78
 Identities = 136/156 (87%), Positives = 145/156 (92%)

Query: 14  PEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDR 73
           P D  + DK+YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLV+SLFLTDLY+DR
Sbjct: 95  PYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDR 154

Query: 74  KLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQF 133
           KLL AEERI QTVEI KH VDIEEKGV+L+LTIVDTPGFGDAVNNTECWKP+ +Y+DQQF
Sbjct: 155 KLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQF 214

Query: 134 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRP 169
           EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHG  P
Sbjct: 215 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGYGP 250


>gi|226492421 septin 12 isoform 2 [Homo sapiens]
          Length = 358

 Score =  263 bits (672), Expect = 2e-70
 Identities = 132/285 (46%), Positives = 192/285 (67%), Gaps = 4/285 (1%)

Query: 25  VGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQ 84
           VG   + +Q+  K++K GF+F +MV G+SGLGKST+V++LF + ++K            Q
Sbjct: 30  VGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPP-GLGVPTPQ 88

Query: 85  TVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLN 144
           T+++   T  IEEKGVKLKLT+ DTPGFGD +NN  CW PI  Y+++Q+EQY ++E  + 
Sbjct: 89  TLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILIT 148

Query: 145 R-KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLK 203
           R ++I D RVHCC+YF+ P GH LRP+D+ F++ L   VN+VP+IA+AD L   E    +
Sbjct: 149 RQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFR 208

Query: 204 ERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGR 263
            RI++ +    I VY  P+   DED + K  + +L++  PFAV+G++      G+ V GR
Sbjct: 209 RRIQQNLRTHCIDVY--PQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGR 266

Query: 264 LYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYR 308
              WGI+EVEN AHC+F  LR++LIR+H+ DLKD+T ++HYENYR
Sbjct: 267 KTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYR 311


>gi|149363638 septin 8 isoform c [Homo sapiens]
          Length = 442

 Score =  262 bits (669), Expect = 4e-70
 Identities = 146/349 (41%), Positives = 211/349 (60%), Gaps = 18/349 (5%)

Query: 12  ATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYK 71
           A PE +      +VGF +LP+Q+  KSV +GF F ++  GE+G+GKSTL+++LF T    
Sbjct: 12  AEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFET 71

Query: 72  DRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQ 131
           +             V +   T D++E  V+LKLTIVD  GFGD +N  E ++PI DY+D 
Sbjct: 72  EEA-----SHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDA 126

Query: 132 QFEQYFRDESGLNRK--NIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIA 189
           QFE Y ++E  + R   +  D R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IA
Sbjct: 127 QFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIA 186

Query: 190 KADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGS 249
           KAD +  SE+ K K +I  E+   G+ +YQFP     +DE   + +  +    PFAV+GS
Sbjct: 187 KADTISKSELHKFKIKIMGELVSNGVQIYQFPT----DDEAVAEINAVMNAHLPFAVVGS 242

Query: 250 NTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRA 309
              V+   + VR R YPWG+V+VEN+ HCDFVKLR MLIR +M DL++ T   HYE YR 
Sbjct: 243 TEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRR 302

Query: 310 HCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKL---IRMKDEELRRM 355
             +++M     QDS  +S  P     T +A+ ++    ++ K+EE+R+M
Sbjct: 303 CKLEEMG---FQDSDGDSQ-PFSLQETYEAKRKEFLSELQRKEEEMRQM 347


>gi|149363689 septin 8 isoform a [Homo sapiens]
          Length = 483

 Score =  262 bits (669), Expect = 4e-70
 Identities = 146/349 (41%), Positives = 211/349 (60%), Gaps = 18/349 (5%)

Query: 12  ATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYK 71
           A PE +      +VGF +LP+Q+  KSV +GF F ++  GE+G+GKSTL+++LF T    
Sbjct: 12  AEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFET 71

Query: 72  DRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQ 131
           +             V +   T D++E  V+LKLTIVD  GFGD +N  E ++PI DY+D 
Sbjct: 72  EEA-----SHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDA 126

Query: 132 QFEQYFRDESGLNRK--NIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIA 189
           QFE Y ++E  + R   +  D R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IA
Sbjct: 127 QFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIA 186

Query: 190 KADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGS 249
           KAD +  SE+ K K +I  E+   G+ +YQFP     +DE   + +  +    PFAV+GS
Sbjct: 187 KADTISKSELHKFKIKIMGELVSNGVQIYQFPT----DDEAVAEINAVMNAHLPFAVVGS 242

Query: 250 NTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRA 309
              V+   + VR R YPWG+V+VEN+ HCDFVKLR MLIR +M DL++ T   HYE YR 
Sbjct: 243 TEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRR 302

Query: 310 HCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKL---IRMKDEELRRM 355
             +++M     QDS  +S  P     T +A+ ++    ++ K+EE+R+M
Sbjct: 303 CKLEEMG---FQDSDGDSQ-PFSLQETYEAKRKEFLSELQRKEEEMRQM 347


>gi|149363661 septin 8 isoform b [Homo sapiens]
          Length = 429

 Score =  262 bits (669), Expect = 4e-70
 Identities = 146/349 (41%), Positives = 211/349 (60%), Gaps = 18/349 (5%)

Query: 12  ATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYK 71
           A PE +      +VGF +LP+Q+  KSV +GF F ++  GE+G+GKSTL+++LF T    
Sbjct: 12  AEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFET 71

Query: 72  DRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQ 131
           +             V +   T D++E  V+LKLTIVD  GFGD +N  E ++PI DY+D 
Sbjct: 72  EEA-----SHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDA 126

Query: 132 QFEQYFRDESGLNRK--NIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIA 189
           QFE Y ++E  + R   +  D R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IA
Sbjct: 127 QFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIA 186

Query: 190 KADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGS 249
           KAD +  SE+ K K +I  E+   G+ +YQFP     +DE   + +  +    PFAV+GS
Sbjct: 187 KADTISKSELHKFKIKIMGELVSNGVQIYQFPT----DDEAVAEINAVMNAHLPFAVVGS 242

Query: 250 NTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRA 309
              V+   + VR R YPWG+V+VEN+ HCDFVKLR MLIR +M DL++ T   HYE YR 
Sbjct: 243 TEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRR 302

Query: 310 HCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKL---IRMKDEELRRM 355
             +++M     QDS  +S  P     T +A+ ++    ++ K+EE+R+M
Sbjct: 303 CKLEEMG---FQDSDGDSQ-PFSLQETYEAKRKEFLSELQRKEEEMRQM 347


>gi|21361478 septin 6 isoform B [Homo sapiens]
          Length = 434

 Score =  260 bits (665), Expect = 1e-69
 Identities = 145/348 (41%), Positives = 214/348 (61%), Gaps = 22/348 (6%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           +VGF +LP+Q+  KSV +GF F ++  GE+GLGKSTL+ +LF T    +           
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE-----PATHTQ 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
             V++  +T D++E  V+LKLTIV T GFGD +N  + +KPI +++D QFE Y ++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 144 NR--KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK 201
            R      D+R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IAKAD +  SE+ K
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 202 LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVR 261
            K +I  E+   G+ +YQFP     +DE   + +  +    PFAVIGS   ++   + +R
Sbjct: 197 FKIKITSELVSNGVQIYQFPT----DDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMR 252

Query: 262 GRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQ 321
            R YPWG V+VEN+AHCDFVKLR MLIR +M DL++ T   HYE YR   +++M  K T 
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTD 312

Query: 322 -DSRMESPIPILPLPTPDAETEKL---IRMKDEELRRMQEMLQRMKQQ 365
            DS+     P     T +A+  +    ++ K+EE+R+M   +QR+K++
Sbjct: 313 PDSK-----PFSLQETYEAKRNEFLGELQKKEEEMRQM--FVQRVKEK 353


>gi|22035581 septin 6 isoform D [Homo sapiens]
          Length = 429

 Score =  260 bits (665), Expect = 1e-69
 Identities = 145/348 (41%), Positives = 214/348 (61%), Gaps = 22/348 (6%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           +VGF +LP+Q+  KSV +GF F ++  GE+GLGKSTL+ +LF T    +           
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE-----PATHTQ 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
             V++  +T D++E  V+LKLTIV T GFGD +N  + +KPI +++D QFE Y ++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 144 NR--KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK 201
            R      D+R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IAKAD +  SE+ K
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 202 LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVR 261
            K +I  E+   G+ +YQFP     +DE   + +  +    PFAVIGS   ++   + +R
Sbjct: 197 FKIKITSELVSNGVQIYQFPT----DDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMR 252

Query: 262 GRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQ 321
            R YPWG V+VEN+AHCDFVKLR MLIR +M DL++ T   HYE YR   +++M  K T 
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTD 312

Query: 322 -DSRMESPIPILPLPTPDAETEKL---IRMKDEELRRMQEMLQRMKQQ 365
            DS+     P     T +A+  +    ++ K+EE+R+M   +QR+K++
Sbjct: 313 PDSK-----PFSLQETYEAKRNEFLGELQKKEEEMRQM--FVQRVKEK 353


>gi|22035579 septin 6 isoform A [Homo sapiens]
          Length = 427

 Score =  260 bits (665), Expect = 1e-69
 Identities = 145/348 (41%), Positives = 214/348 (61%), Gaps = 22/348 (6%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           +VGF +LP+Q+  KSV +GF F ++  GE+GLGKSTL+ +LF T    +           
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE-----PATHTQ 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
             V++  +T D++E  V+LKLTIV T GFGD +N  + +KPI +++D QFE Y ++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 144 NR--KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK 201
            R      D+R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IAKAD +  SE+ K
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 202 LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVR 261
            K +I  E+   G+ +YQFP     +DE   + +  +    PFAVIGS   ++   + +R
Sbjct: 197 FKIKITSELVSNGVQIYQFPT----DDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMR 252

Query: 262 GRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQ 321
            R YPWG V+VEN+AHCDFVKLR MLIR +M DL++ T   HYE YR   +++M  K T 
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTD 312

Query: 322 -DSRMESPIPILPLPTPDAETEKL---IRMKDEELRRMQEMLQRMKQQ 365
            DS+     P     T +A+  +    ++ K+EE+R+M   +QR+K++
Sbjct: 313 PDSK-----PFSLQETYEAKRNEFLGELQKKEEEMRQM--FVQRVKEK 353


>gi|22035577 septin 6 isoform A [Homo sapiens]
          Length = 427

 Score =  260 bits (665), Expect = 1e-69
 Identities = 145/348 (41%), Positives = 214/348 (61%), Gaps = 22/348 (6%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           +VGF +LP+Q+  KSV +GF F ++  GE+GLGKSTL+ +LF T    +           
Sbjct: 22  HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE-----PATHTQ 76

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
             V++  +T D++E  V+LKLTIV T GFGD +N  + +KPI +++D QFE Y ++E  +
Sbjct: 77  PGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKI 136

Query: 144 NR--KNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK 201
            R      D+R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IAKAD +  SE+ K
Sbjct: 137 RRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTK 196

Query: 202 LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVR 261
            K +I  E+   G+ +YQFP     +DE   + +  +    PFAVIGS   ++   + +R
Sbjct: 197 FKIKITSELVSNGVQIYQFPT----DDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMR 252

Query: 262 GRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQ 321
            R YPWG V+VEN+AHCDFVKLR MLIR +M DL++ T   HYE YR   +++M  K T 
Sbjct: 253 ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTD 312

Query: 322 -DSRMESPIPILPLPTPDAETEKL---IRMKDEELRRMQEMLQRMKQQ 365
            DS+     P     T +A+  +    ++ K+EE+R+M   +QR+K++
Sbjct: 313 PDSK-----PFSLQETYEAKRNEFLGELQKKEEEMRQM--FVQRVKEK 353


>gi|8922712 septin 11 [Homo sapiens]
          Length = 429

 Score =  257 bits (657), Expect = 1e-68
 Identities = 140/347 (40%), Positives = 209/347 (60%), Gaps = 20/347 (5%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           +VGF +LP+Q+  KS  +GF F ++  GE+G+GKSTL+ +LF T    D    +      
Sbjct: 21  HVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHN-----E 75

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
             V +   + +++E  V+LKLTIVDT GFGD +N  + +KPI +Y+D QFE Y ++E  +
Sbjct: 76  PGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKI 135

Query: 144 NRK--NIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK 201
            R   N  D R+H CLYFI+P GH L+ +D+  MK L  KVNI+P+IAKAD +  +E+ K
Sbjct: 136 KRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHK 195

Query: 202 LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVR 261
            K +I  E+   G+ +YQFP     ++E   + +  +    PFAV+GS   V+   +  +
Sbjct: 196 FKSKIMSELVSNGVQIYQFP----TDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAK 251

Query: 262 GRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQ 321
            R YPWG+V+VEN+ HCDFVKLR MLIR +M DL++ T   HYE YR   +++M  K T 
Sbjct: 252 ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTD 311

Query: 322 -DSRMESPIPILPLPTPDAETEKL---IRMKDEELRRMQEMLQRMKQ 364
            DS+     P     T +A+  +    ++ K+EE+R+M  M  + K+
Sbjct: 312 PDSK-----PFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKE 353


>gi|30795193 septin 10 isoform 2 [Homo sapiens]
          Length = 431

 Score =  253 bits (646), Expect = 2e-67
 Identities = 137/347 (39%), Positives = 217/347 (62%), Gaps = 20/347 (5%)

Query: 24  YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS 83
           +VGF +LP+Q+  +S+++GF F ++  GE+G+GKSTL+ +LF T+ ++D +         
Sbjct: 23  HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 77

Query: 84  QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGL 143
             V++   T +++E  V+LKLTIV+T GFGD +N  E ++PI DY+D QFE Y ++E  +
Sbjct: 78  PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 137

Query: 144 NRK--NIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK 201
            R      D+R+H CLYFISP GH L+ +D+  MK L  KVNI+P+IAKAD +  +E++K
Sbjct: 138 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 197

Query: 202 LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVR 261
            K ++  E+   G+ +YQFP     +D+   + +  +    PFAV+GS   V+   + V+
Sbjct: 198 FKIKLMSELVSNGVQIYQFPT----DDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVK 253

Query: 262 GRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQ 321
            R YPWG+V+VEN+ HCDFVKLR MLI T+M DL++ T   HYE YR   +++M    T 
Sbjct: 254 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEM--GFTD 311

Query: 322 DSRMESPIPILPLPTPDAETEKL---IRMKDEELRRMQEMLQRMKQQ 365
                 P+ +    T +A+  +     + K+EE+++M   +QR+K++
Sbjct: 312 VGPENKPVSV--QETYEAKRHEFHGERQRKEEEMKQM--FVQRVKEK 354


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,699,697
Number of Sequences: 37866
Number of extensions: 623080
Number of successful extensions: 2835
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 2703
Number of HSP's gapped (non-prelim): 104
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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