Guide to the Human Genome
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Search of human proteins with 9506741

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9506741 glycine N-methyltransferase [Homo sapiens]
         (295 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9506741 glycine N-methyltransferase [Homo sapiens]                 612   e-175
gi|164663805 methyltransferase like 7B [Homo sapiens]                  39   0.005
gi|30795190 Williams-Beuren syndrome chromosome region 27 [Homo ...    36   0.035
gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo...    36   0.046
gi|23199995 Williams Beuren syndrome chromosome region 22 protei...    33   0.30 
gi|227908867 protein arginine methyltransferase 6 [Homo sapiens]       29   5.6  
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ...    29   5.6  
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ...    29   5.6  
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ...    29   5.6  
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ...    29   5.6  
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa...    29   5.6  
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ...    29   5.6  

>gi|9506741 glycine N-methyltransferase [Homo sapiens]
          Length = 295

 Score =  612 bits (1577), Expect = e-175
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQR 60
           MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQR
Sbjct: 1   MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQR 60

Query: 61  VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT 120
           VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT
Sbjct: 61  VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT 120

Query: 121 LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY 180
           LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY
Sbjct: 121 LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY 180

Query: 181 DHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSK 240
           DHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSK
Sbjct: 181 DHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSK 240

Query: 241 FRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD 295
           FRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD
Sbjct: 241 FRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD 295


>gi|164663805 methyltransferase like 7B [Homo sapiens]
          Length = 244

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 16/134 (11%)

Query: 40  SRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKER 99
           S+  E  + + GL    G   +L++ CGTG  +      G  VT +D +    K+  K  
Sbjct: 53  SKKRELFSQIKGLTGASGKVALLELGCGTGA-NFQFYPPGCRVTCLDPNPHFEKFLTKSM 111

Query: 100 WNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLA 159
              RH   ++++V+         +D+ Q A+G  D V+C       L  C       R  
Sbjct: 112 AENRH-LQYERFVVAPG------EDMRQLADGSMDVVVCT------LVLC--SVQSPRKV 156

Query: 160 LKNIASMVRAGGLL 173
           L+ +  ++R GG+L
Sbjct: 157 LQEVRRVLRPGGVL 170


>gi|30795190 Williams-Beuren syndrome chromosome region 27 [Homo
           sapiens]
          Length = 245

 Score = 36.2 bits (82), Expect = 0.035
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 13/81 (16%)

Query: 61  VLDVACGTGVDSIMLVEEGF-SVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWM 119
           +LDVACGTG+ +  L   GF  +  VD S  ML            E A    + +  +  
Sbjct: 71  ILDVACGTGLVAAELRAPGFLQLHGVDGSPGML------------EQAQAPGLYQRLSLC 118

Query: 120 TLDKDVPQSAEGGFDAVICLG 140
           TL ++   S EG FDAV+ +G
Sbjct: 119 TLGQEPLPSPEGTFDAVLIVG 139


>gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo
           sapiens]
          Length = 369

 Score = 35.8 bits (81), Expect = 0.046
 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 6/78 (7%)

Query: 60  RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWM 119
           ++LDV CG G+ +  L   G SV  +D  D+ +K A   + ++  +P  DK +  E    
Sbjct: 149 KILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTA---QCHKSFDPVLDKRI--EYRVC 203

Query: 120 TLDKDVPQSAEGGFDAVI 137
           +L++ V ++AE  FDAV+
Sbjct: 204 SLEEIVEETAE-TFDAVV 220


>gi|23199995 Williams Beuren syndrome chromosome region 22 protein
          [Homo sapiens]
          Length = 281

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 3/82 (3%)

Query: 17 GLPDQYADGEAAR--VWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIM 74
          G P+ + D   AR  V    + D ++R A     LL L     C  +LD+ CGTG+    
Sbjct: 12 GPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCY-LLDIGCGTGLSGSY 70

Query: 75 LVEEGFSVTSVDASDKMLKYAL 96
          L +EG     +D S  ML  A+
Sbjct: 71 LSDEGHYWVGLDISPAMLDEAV 92


>gi|227908867 protein arginine methyltransferase 6 [Homo sapiens]
          Length = 375

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 7/54 (12%)

Query: 39  RSRTAEYKAWLLGLLRQHGCQR---VLDVACGTGVDSIMLVEEGF-SVTSVDAS 88
           R RT  Y+   LG+LR     R   VLDV  GTG+ SI   + G   V +V+AS
Sbjct: 64  RVRTDAYR---LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS 114


>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
           sapiens]
          Length = 1135

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 17  GLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLL 50
           G P+ +   E AR W+ +IG  R  TA + A L+
Sbjct: 844 GWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLV 877


>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
           sapiens]
          Length = 1141

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 17  GLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLL 50
           G P+ +   E AR W+ +IG  R  TA + A L+
Sbjct: 850 GWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLV 883


>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
           sapiens]
          Length = 1091

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 17  GLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLL 50
           G P+ +   E AR W+ +IG  R  TA + A L+
Sbjct: 800 GWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLV 833


>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
           sapiens]
          Length = 1091

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 17  GLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLL 50
           G P+ +   E AR W+ +IG  R  TA + A L+
Sbjct: 800 GWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLV 833


>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
           sapiens]
          Length = 1099

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 17  GLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLL 50
           G P+ +   E AR W+ +IG  R  TA + A L+
Sbjct: 808 GWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLV 841


>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
           sapiens]
          Length = 1150

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 17  GLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLL 50
           G P+ +   E AR W+ +IG  R  TA + A L+
Sbjct: 859 GWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLV 892


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,808,186
Number of Sequences: 37866
Number of extensions: 492754
Number of successful extensions: 970
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 961
Number of HSP's gapped (non-prelim): 12
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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