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Search of human proteins with 94818891
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94818891 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform b [Homo sapiens]
(941 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94818891 type 1 tumor necrosis factor receptor shedding amino... 1904 0.0
gi|94818901 type 1 tumor necrosis factor receptor shedding amino... 1900 0.0
gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 967 0.0
gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 967 0.0
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens] 810 0.0
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens] 810 0.0
gi|132814467 glutamyl aminopeptidase [Homo sapiens] 520 e-147
gi|157266300 membrane alanine aminopeptidase precursor [Homo sap... 495 e-140
gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo ... 478 e-134
gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens] 432 e-121
gi|194239713 laeverin [Homo sapiens] 397 e-110
gi|40316915 arginyl aminopeptidase [Homo sapiens] 95 3e-19
gi|4505029 leukotriene A4 hydrolase [Homo sapiens] 89 2e-17
gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho... 81 5e-15
gi|4507347 TBP-associated factor 2 [Homo sapiens] 43 0.002
gi|110825988 TAR RNA binding protein 1 [Homo sapiens] 32 3.6
>gi|94818891 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform b [Homo sapiens]
Length = 941
Score = 1904 bits (4933), Expect = 0.0
Identities = 941/941 (100%), Positives = 941/941 (100%)
Query: 1 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 60
MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP
Sbjct: 1 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 60
Query: 61 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 120
VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL
Sbjct: 61 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 120
Query: 121 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 180
QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST
Sbjct: 121 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 180
Query: 181 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 240
QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV
Sbjct: 181 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 240
Query: 241 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 300
KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP
Sbjct: 241 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 300
Query: 301 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360
YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF
Sbjct: 301 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360
Query: 361 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 420
GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS
Sbjct: 361 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 420
Query: 421 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 480
TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD
Sbjct: 421 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 480
Query: 481 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 540
SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR
Sbjct: 481 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 540
Query: 541 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 600
NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF
Sbjct: 541 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 600
Query: 601 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 660
NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL
Sbjct: 601 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 660
Query: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720
SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG
Sbjct: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720
Query: 721 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 780
SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE
Sbjct: 721 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 780
Query: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840
GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG
Sbjct: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840
Query: 841 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 900
RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE
Sbjct: 841 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 900
Query: 901 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 941
NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM
Sbjct: 901 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 941
>gi|94818901 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform a [Homo sapiens]
Length = 948
Score = 1900 bits (4923), Expect = 0.0
Identities = 939/939 (100%), Positives = 939/939 (100%)
Query: 1 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 60
MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP
Sbjct: 1 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 60
Query: 61 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 120
VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL
Sbjct: 61 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 120
Query: 121 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 180
QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST
Sbjct: 121 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 180
Query: 181 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 240
QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV
Sbjct: 181 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 240
Query: 241 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 300
KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP
Sbjct: 241 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 300
Query: 301 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360
YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF
Sbjct: 301 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360
Query: 361 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 420
GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS
Sbjct: 361 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 420
Query: 421 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 480
TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD
Sbjct: 421 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 480
Query: 481 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 540
SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR
Sbjct: 481 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 540
Query: 541 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 600
NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF
Sbjct: 541 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 600
Query: 601 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 660
NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL
Sbjct: 601 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 660
Query: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720
SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG
Sbjct: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720
Query: 721 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 780
SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE
Sbjct: 721 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 780
Query: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840
GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG
Sbjct: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840
Query: 841 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 900
RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE
Sbjct: 841 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 900
Query: 901 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLE 939
NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLE
Sbjct: 901 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLE 939
>gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 967 bits (2501), Expect = 0.0
Identities = 477/934 (51%), Positives = 646/934 (69%), Gaps = 15/934 (1%)
Query: 13 MSFLLSSLLALLTVSTPSWCQSTE---ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHA 69
++ +L + S PS TE A P ++G FPW ++RLP VIP+HYDL +H
Sbjct: 25 LTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHP 84
Query: 70 NLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSE--EPLQVLEHPR 127
NLT+L F + K+E+ S T IILHS L+I+ ATL+ R + + L+VL +P
Sbjct: 85 NLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPA 144
Query: 128 QEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAA 187
EQIALL PE L L Y V + + L + F GFYKSTYRT GE RILA T FEPT A
Sbjct: 145 HEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQA 204
Query: 188 RMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLV 247
RMAFPCFDEP FKA+FSIKIRRE RH+A+SNMP VK++ + GL+EDHF+ TVKMSTYLV
Sbjct: 205 RMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLV 264
Query: 248 AFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQD 307
A+I+ DF S+S T SGVKVS+YA PDK NQ YAL A++ LL+FYE YF I YPL K D
Sbjct: 265 AYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLD 324
Query: 308 LAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367
L AIPDF GAMENWGL TYRE++LLFD + SSAS KL +T +AHELAHQWFGNLVTME
Sbjct: 325 LIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTME 384
Query: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPA 427
WWND+WL EGFAK+ME ++V+ T+PEL+ DYF CF+ + D+LNSS P+S P E P
Sbjct: 385 WWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPT 444
Query: 428 QIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASIC- 486
QI+EMFD+VSY+KGACILNML+++L + F+ GI+QYL+K SY+N KN+DLW S+++ C
Sbjct: 445 QIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCL 504
Query: 487 PTDGVKGMDGFC-SRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMK 545
+D G G C S + +S+ + E +VK MM TWTLQKG PL+ + G ++ ++
Sbjct: 505 ESDFTSG--GVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQ 562
Query: 546 QEHYMKG------SDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIK 599
QE +++G A YLWH+PLT+ TS S+++HR +LK+KTD L LPE+ W+K
Sbjct: 563 QERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVK 622
Query: 600 FNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALD 659
FNV NGYYIVHYE GWD L L HT + DR LI++ FQLV G+L+++KALD
Sbjct: 623 FNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALD 682
Query: 660 LSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDE 719
++ YL+HET + +GL+ L Y +M++R+++++ K +L++ + +ID+Q+W+D+
Sbjct: 683 MTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDK 742
Query: 720 GSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQST 779
GSV +RMLRS LL LAC N+ PC+Q+A F +W ES+G L++P DV V++VGAQ+T
Sbjct: 743 GSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTT 802
Query: 780 EGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLI 839
GW++L +Y+ S+SS E+++I +AL ++++EKL L++ +G IKTQ +L I
Sbjct: 803 AGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAI 862
Query: 840 GRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLK 899
R P G LAW F+R+NW L++KF+LGS I ++ GTT FS++ +L+EVK FF SL+
Sbjct: 863 ARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLE 922
Query: 900 ENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 933
GS L Q +ETI +NI W++KN +R WL
Sbjct: 923 AQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWL 956
>gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 967 bits (2501), Expect = 0.0
Identities = 477/934 (51%), Positives = 646/934 (69%), Gaps = 15/934 (1%)
Query: 13 MSFLLSSLLALLTVSTPSWCQSTE---ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHA 69
++ +L + S PS TE A P ++G FPW ++RLP VIP+HYDL +H
Sbjct: 25 LTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHP 84
Query: 70 NLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSE--EPLQVLEHPR 127
NLT+L F + K+E+ S T IILHS L+I+ ATL+ R + + L+VL +P
Sbjct: 85 NLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPA 144
Query: 128 QEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAA 187
EQIALL PE L L Y V + + L + F GFYKSTYRT GE RILA T FEPT A
Sbjct: 145 HEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQA 204
Query: 188 RMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLV 247
RMAFPCFDEP FKA+FSIKIRRE RH+A+SNMP VK++ + GL+EDHF+ TVKMSTYLV
Sbjct: 205 RMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLV 264
Query: 248 AFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQD 307
A+I+ DF S+S T SGVKVS+YA PDK NQ YAL A++ LL+FYE YF I YPL K D
Sbjct: 265 AYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLD 324
Query: 308 LAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367
L AIPDF GAMENWGL TYRE++LLFD + SSAS KL +T +AHELAHQWFGNLVTME
Sbjct: 325 LIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTME 384
Query: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPA 427
WWND+WL EGFAK+ME ++V+ T+PEL+ DYF CF+ + D+LNSS P+S P E P
Sbjct: 385 WWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPT 444
Query: 428 QIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASIC- 486
QI+EMFD+VSY+KGACILNML+++L + F+ GI+QYL+K SY+N KN+DLW S+++ C
Sbjct: 445 QIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCL 504
Query: 487 PTDGVKGMDGFC-SRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMK 545
+D G G C S + +S+ + E +VK MM TWTLQKG PL+ + G ++ ++
Sbjct: 505 ESDFTSG--GVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQ 562
Query: 546 QEHYMKG------SDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIK 599
QE +++G A YLWH+PLT+ TS S+++HR +LK+KTD L LPE+ W+K
Sbjct: 563 QERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVK 622
Query: 600 FNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALD 659
FNV NGYYIVHYE GWD L L HT + DR LI++ FQLV G+L+++KALD
Sbjct: 623 FNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALD 682
Query: 660 LSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDE 719
++ YL+HET + +GL+ L Y +M++R+++++ K +L++ + +ID+Q+W+D+
Sbjct: 683 MTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDK 742
Query: 720 GSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQST 779
GSV +RMLRS LL LAC N+ PC+Q+A F +W ES+G L++P DV V++VGAQ+T
Sbjct: 743 GSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTT 802
Query: 780 EGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLI 839
GW++L +Y+ S+SS E+++I +AL ++++EKL L++ +G IKTQ +L I
Sbjct: 803 AGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAI 862
Query: 840 GRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLK 899
R P G LAW F+R+NW L++KF+LGS I ++ GTT FS++ +L+EVK FF SL+
Sbjct: 863 ARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLE 922
Query: 900 ENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 933
GS L Q +ETI +NI W++KN +R WL
Sbjct: 923 AQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWL 956
>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]
Length = 1025
Score = 810 bits (2093), Expect = 0.0
Identities = 418/903 (46%), Positives = 575/903 (63%), Gaps = 38/903 (4%)
Query: 39 PKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSH 98
P ++G FPW +IRLP V+P+ Y+L +H NLT++TF G+ + + A Q T IILHS
Sbjct: 153 PFATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHST 212
Query: 99 HLQISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSET 158
ISR T + E+ ++LE+ QIA++APE LL G YT+ I Y+ N+S +
Sbjct: 213 GHNISRVTFMSAVSSQ--EKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSS 270
Query: 159 FHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISN 218
++GFY +Y + E + A+TQFEP AAR AFPCFDEPAFKA+F IKI R+ ++ A+SN
Sbjct: 271 YYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSN 330
Query: 219 MPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQ 278
MP SV + +GL++D F +VKMSTYLVAFI+ + +++S+ +G VS+YAVP+KI Q
Sbjct: 331 MPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDV-NGTLVSIYAVPEKIGQ 389
Query: 279 ADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEK 338
YAL+ V LLEF+++YF I YPL K DL AIPDF++GAMENWGL T+RE LL+D+
Sbjct: 390 VHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNT 449
Query: 339 SSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGD 398
SS + + +T +AHELAHQWFGNLVTM+WWNDLWLNEGFA FME+ S+ EL +
Sbjct: 450 SSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYE 509
Query: 399 YFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFK 458
F F M+ D+LNSSHP+S+ V++ QI EMFD +SY KG+ +L ML+ YLS D F+
Sbjct: 510 DFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQ 569
Query: 459 SGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVK 518
+V YL HSY + +++DLWDS + + +DVK
Sbjct: 570 HAVVLYLHNHSYASIQSDDLWDSFNEVT-------------------------NQTLDVK 604
Query: 519 TMMNTWTLQKGFPLITITVRGRNVHMKQEHY---MKGSDGAPDTGYLWHVPLTFIT---- 571
MM TWTLQKGFPL+T+ +G+ + ++QE + MK DT YLWH+PL+++T
Sbjct: 605 RMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRN 664
Query: 572 -SKSDMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTA 630
SK V LL K+ V+ L EEV W+K N+ MNGYYIVHY DD W++L LK
Sbjct: 665 YSKYQSVS--LLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYV 722
Query: 631 VSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKR 690
+S DRA+LINN F+L +GK+ +++A DL YL +E P+ + L + +Y L+EK
Sbjct: 723 LSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEKL 782
Query: 691 DMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGY 750
++ ++ + +LL++ I +QTWTDEG+ S R LRS LL AC HN C A
Sbjct: 783 GYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMKL 842
Query: 751 FRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQN 810
F W SNG SLP DV VF VGA++ +GW FL KY S EK++I AL +++
Sbjct: 843 FDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSED 902
Query: 811 KEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSS 870
KL WL+ S GD +TQ+ I+ +GR+ G+ LAW F+++NWNKLVQKF LGS +
Sbjct: 903 VRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYT 962
Query: 871 IAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIR 930
I ++V G+T FST+T L EV+ FF + E +LRCVQ+ +E I+ NI WM+KN +
Sbjct: 963 IQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLT 1022
Query: 931 VWL 933
WL
Sbjct: 1023 WWL 1025
>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]
Length = 1011
Score = 810 bits (2093), Expect = 0.0
Identities = 418/903 (46%), Positives = 575/903 (63%), Gaps = 38/903 (4%)
Query: 39 PKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSH 98
P ++G FPW +IRLP V+P+ Y+L +H NLT++TF G+ + + A Q T IILHS
Sbjct: 139 PFATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHST 198
Query: 99 HLQISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSET 158
ISR T + E+ ++LE+ QIA++APE LL G YT+ I Y+ N+S +
Sbjct: 199 GHNISRVTFMSAVSSQ--EKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSS 256
Query: 159 FHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISN 218
++GFY +Y + E + A+TQFEP AAR AFPCFDEPAFKA+F IKI R+ ++ A+SN
Sbjct: 257 YYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSN 316
Query: 219 MPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQ 278
MP SV + +GL++D F +VKMSTYLVAFI+ + +++S+ +G VS+YAVP+KI Q
Sbjct: 317 MPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDV-NGTLVSIYAVPEKIGQ 375
Query: 279 ADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEK 338
YAL+ V LLEF+++YF I YPL K DL AIPDF++GAMENWGL T+RE LL+D+
Sbjct: 376 VHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNT 435
Query: 339 SSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGD 398
SS + + +T +AHELAHQWFGNLVTM+WWNDLWLNEGFA FME+ S+ EL +
Sbjct: 436 SSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYE 495
Query: 399 YFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFK 458
F F M+ D+LNSSHP+S+ V++ QI EMFD +SY KG+ +L ML+ YLS D F+
Sbjct: 496 DFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQ 555
Query: 459 SGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVK 518
+V YL HSY + +++DLWDS + + +DVK
Sbjct: 556 HAVVLYLHNHSYASIQSDDLWDSFNEVT-------------------------NQTLDVK 590
Query: 519 TMMNTWTLQKGFPLITITVRGRNVHMKQEHY---MKGSDGAPDTGYLWHVPLTFIT---- 571
MM TWTLQKGFPL+T+ +G+ + ++QE + MK DT YLWH+PL+++T
Sbjct: 591 RMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRN 650
Query: 572 -SKSDMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTA 630
SK V LL K+ V+ L EEV W+K N+ MNGYYIVHY DD W++L LK
Sbjct: 651 YSKYQSVS--LLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYV 708
Query: 631 VSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKR 690
+S DRA+LINN F+L +GK+ +++A DL YL +E P+ + L + +Y L+EK
Sbjct: 709 LSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEKL 768
Query: 691 DMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGY 750
++ ++ + +LL++ I +QTWTDEG+ S R LRS LL AC HN C A
Sbjct: 769 GYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMKL 828
Query: 751 FRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQN 810
F W SNG SLP DV VF VGA++ +GW FL KY S EK++I AL +++
Sbjct: 829 FDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSED 888
Query: 811 KEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSS 870
KL WL+ S GD +TQ+ I+ +GR+ G+ LAW F+++NWNKLVQKF LGS +
Sbjct: 889 VRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYT 948
Query: 871 IAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIR 930
I ++V G+T FST+T L EV+ FF + E +LRCVQ+ +E I+ NI WM+KN +
Sbjct: 949 IQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLT 1008
Query: 931 VWL 933
WL
Sbjct: 1009 WWL 1011
>gi|132814467 glutamyl aminopeptidase [Homo sapiens]
Length = 957
Score = 520 bits (1338), Expect = e-147
Identities = 308/937 (32%), Positives = 497/937 (53%), Gaps = 69/937 (7%)
Query: 25 TVSTPSWCQSTEASPK-----------RSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTT 73
T PS S+ ASP S+ W RLP++V PVHYDL + L
Sbjct: 53 TAPAPSHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEE 112
Query: 74 LTFWGTTKVEITASQPTSTIILHSHHLQISRAT-LRKGAGERLSEEPLQVLEHPRQEQIA 132
T+ GT + I S PT + LH +I+R L++ +G+++ + E+ +QE +
Sbjct: 113 DTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVR--RCFEYKKQEYVV 170
Query: 133 LLAPEPLLV----GLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAAR 188
+ A E L GL Y + + +AG L+ + GFY++TY T+ G+++ + +T EPT AR
Sbjct: 171 VEAEEELTPSSGDGL-YLLTMEFAGWLNGSLVGFYRTTY-TENGQVKSIVATDHEPTDAR 228
Query: 189 MAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVA 248
+FPCFDEP KA+++I I + A+SNMP+ K +V + F+ +V MSTYLV
Sbjct: 229 KSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVC 288
Query: 249 FIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQDL 308
F + F+SV +I+ SG +++Y P++ + A+YA + ++ +++E+YF++ Y LPK D
Sbjct: 289 FAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDK 348
Query: 309 AAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEW 368
AIPDF +GAMENWGL TYRE+ LL+D ++S++S++ + VAHEL HQWFGN+VTM+W
Sbjct: 349 IAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDW 408
Query: 369 WNDLWLNEGFAKFMEFVSVSVTHPELKVGD-YFFGKCFDAMEVDALNSSHPVSTPVENPA 427
W DLWLNEGFA F EF+ V+ + ++ D E D+L SSHP+ V P
Sbjct: 409 WEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPD 468
Query: 428 QIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICP 487
+I +FD +SY KG+ IL ML +++ + F+ G YL+K+ +KN K D W ++
Sbjct: 469 EITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEE--- 525
Query: 488 TDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQ- 546
SR + VK +M+TWT Q G+P++ + +N+ K+
Sbjct: 526 ----------ASR--------------LPVKEVMDTWTRQMGYPVLNVN-GVKNITQKRF 560
Query: 547 --EHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLI---LPEEVEWIKFN 601
+ S D GY W++P+ + F K + + P ++K N
Sbjct: 561 LLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKIN 620
Query: 602 VGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLS 661
G+Y V+YE WDS+ L H SS DRASLI++AF L L + AL+L+
Sbjct: 621 PDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLT 680
Query: 662 LYLKHETEIMP---VFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTD 718
YLK E +P V + +I M++ D E+ + + ++ + D W D
Sbjct: 681 KYLKREENFLPWQRVISAVTYIISMFE-----DDKELYPMIEEYFQGQVKPIADSLGWND 735
Query: 719 EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQS 778
G ++LRS +L AC + + A F +W NG +SLPV++ L V+ G Q+
Sbjct: 736 AGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQW--LNGTVSLPVNLRLLVYRYGMQN 793
Query: 779 TE---GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQI 835
+ W++ +YQ + + EK ++ + L +N L LD + IKTQ+ +
Sbjct: 794 SGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTV 853
Query: 836 LTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFF 895
+ I N G +AW +++ NW+ LV ++ L + ++ +V F+T +L +++ FF
Sbjct: 854 IRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVT-IAEPFNTELQLWQMESFF 912
Query: 896 SSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVW 932
+ + G+ + +Q +ET++ NI W+ ++ + IR W
Sbjct: 913 AKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREW 949
>gi|157266300 membrane alanine aminopeptidase precursor [Homo
sapiens]
Length = 967
Score = 495 bits (1275), Expect = e-140
Identities = 312/942 (33%), Positives = 477/942 (50%), Gaps = 65/942 (6%)
Query: 27 STPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTT-----LTFWGTTK 81
+TPS +T + + WN+ RLP + P Y + + LT F G++
Sbjct: 49 TTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSST 108
Query: 82 VEITASQPTSTIILHSHHLQIS-----RATLRKGAGERLSEEPLQVLEHPRQEQIALLAP 136
V T + T II+HS L + R LR G + + L P + + L
Sbjct: 109 VRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKG 168
Query: 137 EPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELR-ILASTQFEPTAARMAFPCFD 195
L+ Y + + G L++ GFY+S Y EG +R ++A+TQ + AR +FPCFD
Sbjct: 169 S-LVKDSQYEMDSEFEGELADDLAGFYRSEYM--EGNVRKVVATTQMQAADARKSFPCFD 225
Query: 196 EPAFKASFSIKIRREPRHLAISNM-PLVKSVTVAE--GLIEDHFDVTVKMSTYLVAFIIS 252
EPA KA F+I + A+SNM P S + E F T KMSTYL+AFI+S
Sbjct: 226 EPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVS 285
Query: 253 DFESVSKITKSGVKVSVYAVPDKI--NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAA 310
+F+ V K +GV + ++A P I DYAL+ +L F+ ++ PYPLPK D
Sbjct: 286 EFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIG 345
Query: 311 IPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWN 370
+PDF +GAMENWGL TYRE++LLFD SS+S+K + +AHELAHQWFGNLVT+EWWN
Sbjct: 346 LPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWN 405
Query: 371 DLWLNEGFAKFMEFVSVSVTHPELKVGDYF-FGKCFDAMEVDALNSSHPVSTP---VENP 426
DLWLNEGFA ++E++ P + D + M VDAL SSHP+STP + P
Sbjct: 406 DLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTP 465
Query: 427 AQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASIC 486
AQI E+FD +SY KGA +L ML +LS D FK G+ YL +Y+NT +LWD +
Sbjct: 466 AQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAV 525
Query: 487 PTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITI-TVRGRNVHMK 545
+ Q V+ +MN WTLQ GFP+IT+ T G +
Sbjct: 526 NNRSI--------------------QLPTTVRDIMNRWTLQMGFPVITVDTSTGT---LS 562
Query: 546 QEHYMKGSDG----APDTGYLWHVPLTFITSKSDMVHRFLLKTKT-DVLILPEEVEWIKF 600
QEH++ D + Y+W VP+T I +L+ + + L EW+
Sbjct: 563 QEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLL 622
Query: 601 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 660
N+ + GYY V+Y+++ W + L+ H+A+ +RA +IN+AF L S K+ + AL+
Sbjct: 623 NLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNN 682
Query: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLI-----DKQT 715
+L+L E + MP L+ L +KLM D +EV K +L + + L +
Sbjct: 683 TLFLIEERQYMPWEAALSSL-SYFKLM--FDRSEVYGPMKNYLKKQVTPLFIHFRNNTNN 739
Query: 716 WTD-EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVF-- 772
W + ++ ++ + AC + C + G F++W E+ N + ++ V+
Sbjct: 740 WREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCN 799
Query: 773 AVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEF 832
A+ E WDF + +++ + E ++ AL ++ L L + D I+ Q+
Sbjct: 800 AIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDA 859
Query: 833 PQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVK 892
+ I N +G L W F++ NW KL + GS S ++++ T +FST L++++
Sbjct: 860 TSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLE 919
Query: 893 GFFSSLKEN--GSQLRCVQQTIETIEENIGWMDKNFDKIRVW 932
F +E GS R ++Q +E + NI W+ +N + + W
Sbjct: 920 QFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQW 961
>gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo
sapiens]
Length = 1024
Score = 478 bits (1230), Expect = e-134
Identities = 285/925 (30%), Positives = 456/925 (49%), Gaps = 61/925 (6%)
Query: 39 PKRSDGTPF-PWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHS 97
P + P+ PW ++RL ++ P+HY+L++ A + TF G VEI T ++LH+
Sbjct: 125 PSEEEREPWEPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHA 184
Query: 98 HHLQISRATLRKGAGERLSEEPLQ-VLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLS 156
+ + + L + P+ +P+ + + ++ L Y + I Y +
Sbjct: 185 SRVAVEKVQLAEDRA--FGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIE 242
Query: 157 ETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAI 216
GF++S+Y GE R L TQF PT AR AFPCFDEP +KA+F I I+ + +L++
Sbjct: 243 NELLGFFRSSY-VLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSL 301
Query: 217 SNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKI 276
SNMP+ SV +G + DHF T MSTY +A+ I +F TKSGV V +YA PD I
Sbjct: 302 SNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAI 361
Query: 277 NQA--DYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLF 334
+ DYAL L+EFYEDYF +PY LPK DL A+P AMENWGL+ + E +L
Sbjct: 362 RRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILL 421
Query: 335 DAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHP-- 392
D SS S L +TM + HE+ HQWFG+LVT WW D+WL EGFA + EFV +P
Sbjct: 422 DPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGW 481
Query: 393 ELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYL 452
++ + + M +D L SSHPVS V I +FD ++Y KGA ++ ML ++
Sbjct: 482 NMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLQATDIDRVFDWIAYKKGAALIRMLANFM 541
Query: 453 SADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQ 512
F+ G+ YL H Y N DLW++++ +G
Sbjct: 542 GHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNG---------------------- 579
Query: 513 EGVDVKTMMNTWTLQKGFPLITI---TVRGRNVHMKQEHYMKGSDG------APDTGYLW 563
+ V+++ +M+ WTLQ G+P+ITI T + + Q+H++ + YLW
Sbjct: 580 KYVNIQEVMDQWTLQMGYPVITILGNTTAENRIIITQQHFIYDISAKTKALKLQNNSYLW 639
Query: 564 HVPLTFITSKSDMVHRFLL-----KTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWD 618
+PLT + V + K++ + ++ W+ N+ GY+ V+Y+ W
Sbjct: 640 QIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDKGSWLLGNINQTGYFRVNYDLRNWR 699
Query: 619 SLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLN 678
L L H +S ++RA LI++AF L G L L++ YL E + +P
Sbjct: 700 LLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASR 759
Query: 679 ELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTD--------EGSVSERMLRSQ 730
L P+ KL+++ + + F ++++ + K W + S LR +
Sbjct: 760 ALYPLDKLLDRMENYNI---FNEYILKQVATTYIKLGWPKNNFNGSLVQASYQHEELRRE 816
Query: 731 LLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQ--STEGWDFLYSK 788
+++LAC + C Q+A W SN N +P++V V+ G + W+F++ K
Sbjct: 817 VIMLACSFGNKHCHQQASTLISDWISSNRN-RIPLNVRDIVYCTGVSLLDEDVWEFIWMK 875
Query: 789 YQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPL 848
+ + + +EK + AL + ++ L LL+ S + + Q+ ++ + RNP G L
Sbjct: 876 FHSTTAVSEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDL 935
Query: 849 AWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCV 908
AW+F R W L ++ + ++ G T +T L+E+K F + +G
Sbjct: 936 AWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKNY--DGVAAASF 993
Query: 909 QQTIETIEENIGWMDKNFDKIRVWL 933
+ +ET+E N+ W D++ WL
Sbjct: 994 SRAVETVEANVRWKMLYQDELFQWL 1018
>gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens]
Length = 919
Score = 432 bits (1110), Expect = e-121
Identities = 290/900 (32%), Positives = 449/900 (49%), Gaps = 54/900 (6%)
Query: 53 RLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAG 112
RLP V P++Y L + +L TF G + Q T+ I+++ + I A+
Sbjct: 53 RLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGD 112
Query: 113 ERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEG 172
E + E++ L P L G T+ I + G L++ GFY+S Y T G
Sbjct: 113 EEIHATGFNYQNE--DEKVTLSFPSTLQTGTG-TLKIDFVGELNDKMKGFYRSKYTTPSG 169
Query: 173 ELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLV--KSVTVAEG 230
E+R A TQFE T AR AFPC+DEPA KA+F I + +A+SNM ++ K E
Sbjct: 170 EVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDEN 229
Query: 231 LIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLL 290
L+E F T MSTYLVAF++ +++ V +K GV V VY K Q +AL+ A L
Sbjct: 230 LVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTL 289
Query: 291 EFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMT 350
FY+DYF++PYPLPK DL AI DF +GAMENWGL TYRE+ALL D + S +SS+ + +
Sbjct: 290 PFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALV 349
Query: 351 VAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFD-AME 409
V HELAHQWFGNLVTMEWW LWLNEGFA ++E++ V PE + F + A E
Sbjct: 350 VGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQE 409
Query: 410 VDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHS 469
+DAL++SHP+ V +P+++ E+FD +SY KGA ++ ML +Y+ FK G+ YL K
Sbjct: 410 LDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQ 469
Query: 470 YKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKG 529
KN EDLW+S+ + G + +MNTWT Q G
Sbjct: 470 QKNAATEDLWESLENA---------------------------SGKPIAAVMNTWTKQMG 502
Query: 530 FPLITITVR----GRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKS-DMVHRFLLKT 584
FPLI + R + + Q+ + G + W VP+T TS+ + +L
Sbjct: 503 FPLIYVEAEQVEDDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMD 562
Query: 585 KTDVLILPEEV---EWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLIN 641
K ++ ++ + V +W+K N+G G+Y Y +SL ++ ++ DR L N
Sbjct: 563 KPEMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIR--DLSLPPVDRLGLQN 620
Query: 642 NAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLN-ELIPMYKLMEKRDMNEVETQFK 700
+ F L G +S + L + +E V+ L+ L + L+ D E +F
Sbjct: 621 DLFSLARAGIISTVEVLKVMEAFVNEPN-YTVWSDLSCNLGILSTLLSHTDFYEEIQEFV 679
Query: 701 AFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGN 760
+ + + + EG + + +LR +L ++ ++ A F+ E
Sbjct: 680 KDVFSPIGERLGWDPKPGEGHL-DALLRGLVLGKLGKAGHKATLEEARRRFKDHVEGKQI 738
Query: 761 LS--LPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLL 818
LS L V L V G +T D + ++ + EK++IE L T + +Q +L
Sbjct: 739 LSADLRSPVYLTVLKHGDGTT--LDIMLKLHKQADMQEEKNRIERVLGATLLPDLIQKVL 796
Query: 819 DESFKGDKIKTQEFPQIL-TLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMG 877
+ ++++ Q+ ++ + G + G AW+F++ NW +L +++ G I+ ++
Sbjct: 797 TFAL-SEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQ-GGFLISRLIKL 854
Query: 878 TTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEK 937
+ F+ EVK FF S ++ R +QQ E I N W+ ++ + I +L K
Sbjct: 855 SVEGFAVDKMAGEVKAFFESHPAPSAE-RTIQQCCENILLNAAWLKRDAESIHQYLLQRK 913
>gi|194239713 laeverin [Homo sapiens]
Length = 990
Score = 397 bits (1021), Expect = e-110
Identities = 272/934 (29%), Positives = 461/934 (49%), Gaps = 81/934 (8%)
Query: 46 PFPWNKIRLPEYVIPVHYDLLIHANLT-------TLTFWGTTKVEITASQPTSTIILHSH 98
P PW+++RLP +++P+HYDL + L +L F G + + + TS ++LHS
Sbjct: 90 PGPWDQLRLPPWLVPLHYDLELWPQLRPDELPAGSLPFTGRVNITVRCTVATSRLLLHSL 149
Query: 99 HLQISRATLR----KGAGER-LSEEPLQVLEHPRQ-EQIALLAPEPLLVGLPYTVVIHYA 152
RA +R G G + P+ + E + L EPL G Y + + ++
Sbjct: 150 FQDCERAEVRGPLSPGTGNATVGRVPVDDVWFALDTEYMVLELSEPLKPGSSYELQLSFS 209
Query: 153 GNLSETFH-GFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREP 211
G + E G + + Y T +GE R L ++Q EPT AR FPCFDEPA KA+F+I + P
Sbjct: 210 GLVKEDLREGLFLNVY-TDQGERRALLASQLEPTFARYVFPCFDEPALKATFNITMIHHP 268
Query: 212 RHLAISNMPLV-----KSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVK 266
++A+SNMP + + V ++ + F T M TYLVAF+I D++ V++ T+ G +
Sbjct: 269 SYVALSNMPKLGQSEKEDVNGSKWTVTT-FSTTPHMPTYLVAFVICDYDHVNR-TERGKE 326
Query: 267 VSVYAVPDKI--NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGL 324
+ ++A D I AD+AL+ + F ED F+I Y LPK D+ A+P F + AMENWGL
Sbjct: 327 IRIWARKDAIANGSADFALNITGPIFSFLEDLFNISYSLPKTDIIALPSFDNHAMENWGL 386
Query: 325 TTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEF 384
+ ES LL + + K I+ V+HE+ HQWFGNLVTM WWN++WLNEGFA + EF
Sbjct: 387 MIFDESGLLLEPKDQLTEKKTLISYVVSHEIGHQWFGNLVTMNWWNNIWLNEGFASYFEF 446
Query: 385 VSVSVTHPELKVGDYFFGKCF-DAMEVDALNSSHPVSTPVEN--PAQIREMFDDVSYDKG 441
++ +P+L + FF + + D + V+ VEN ++I+E+FD +Y KG
Sbjct: 447 EVINYFNPKLPRNEIFFSNILHNILREDHALVTRAVAMKVENFKTSEIQELFDIFTYSKG 506
Query: 442 ACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLW--------DSMASICPTDGVKG 493
A + ML +L+ F S + YL+ SY N + +DLW D I P
Sbjct: 507 ASMARMLSCFLNEHLFVSALKSYLKTFSYSNAEQDDLWRHFQMAIDDQSTVILP------ 560
Query: 494 MDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQEHYMKGS 553
+K +M++WT Q GFP+IT+ V V ++ Y++
Sbjct: 561 ---------------------ATIKNIMDSWTHQSGFPVITLNV-STGVMKQEPFYLENI 598
Query: 554 DGAP--DTGYLWHVPLTFITSKSDMVHRFL---LKTKTDVLILPEEVEWIKFNVGMNGYY 608
+ W VP+ +I + + +L K ++ + + +W+ N+ M GYY
Sbjct: 599 KNRTLLTSNDTWIVPILWIKNGTTQPLVWLDQSSKVFPEMQVSDSDHDWVILNLNMTGYY 658
Query: 609 IVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHET 668
V+Y+ GW L L+ A+ R LI++AF L + IE AL+L+ YL E
Sbjct: 659 RVNYDKLGWKKLNQQLEKDPKAIPVIHRLQLIDDAFSLSKNNYIEIETALELTKYLAEED 718
Query: 669 EIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLR-------DLIDKQTWTDEGS 721
EI+ L L+ L+ + ++ ++ + K +L++ L +I + +
Sbjct: 719 EIIVWHTVLVNLVTR-DLVSEVNIYDIYSLLKRYLLKRLNLIWNIYSTIIRENVLALQDD 777
Query: 722 VSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGN-LSLPVDVTLAVFAVGAQSTE 780
+ +L + AC + C+Q ++ F KW + N + P+ + + + S +
Sbjct: 778 YLALISLEKLFVTACWLGLEDCLQLSKELFAKWVDHPENEIPYPIKDVVLCYGIALGSDK 837
Query: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840
WD L + Y + + EK Q+ +A+ +++ L ++ + + E I+ ++
Sbjct: 838 EWDILLNTYTNTTNKEEKIQLAYAMSCSKDPWILNRYMEYAISTSPFTSNE-TNIIEVVA 896
Query: 841 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 900
+ VG +A FL NW + +++ G+ S+ +++ +T ++ E++ FFS++ E
Sbjct: 897 SSEVGRYVAKDFLVNNWQAVSKRY--GTQSLINLIYTIGRTVTTDLQIVELQQFFSNMLE 954
Query: 901 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQ 934
++R V ++TI+ K +I WL+
Sbjct: 955 EHQRIR-VHANLQTIKNENLKNKKLSARIAAWLR 987
>gi|40316915 arginyl aminopeptidase [Homo sapiens]
Length = 650
Score = 95.1 bits (235), Expect = 3e-19
Identities = 110/443 (24%), Positives = 178/443 (40%), Gaps = 56/443 (12%)
Query: 78 GTTKVEITASQP--TSTIILHSHH-LQISRATLRKG--AGERLSEEPLQVLEHPRQ---E 129
GT +++ +P + + L SH L+++ A LR+ E EP+ P +
Sbjct: 61 GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120
Query: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARM 189
+ + P+P V++ Y + E + + +T G+ + TQ + R
Sbjct: 121 ALCVSFPQPCRAAERLQVLLTY--RVGEGPGVCWLAPEQTA-GKKKPFVYTQGQAVLNRA 177
Query: 190 AFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAF 249
FPCFD PA K +S I A+ + S G + F + + +YL+A
Sbjct: 178 FFPCFDTPAVKYKYSALIEVPDGFTAVMSA----STWEKRGPNKFFFQMCQPIPSYLIAL 233
Query: 250 IISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVT-LLEFYEDYFSIPYPLPKQDL 308
I D S + G + V+A P I+ A + + L E F PY + DL
Sbjct: 234 AIGDLVSA----EVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFG-PYVWGRYDL 288
Query: 309 AAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367
+P F G MEN LT L D + + HE++H WFGNLVT
Sbjct: 289 LFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADV---------IIHEISHSWFGNLVTNA 339
Query: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFG---KCFDAMEVDALNSSHPVSTPVE 424
W + WLNEGF + + ++ FG C +A AL H T E
Sbjct: 340 NWGEFWLNEGFTMY----------AQRRISTILFGAAYTCLEAATGRALLRQHMDITGEE 389
Query: 425 NPA-QIR----------EMFDDVSYDKGACILNMLREYL-SADAFKSGIVQYLQKHSYKN 472
NP ++R + +++ Y+KG C ++ L + D F S + Y+ + +++
Sbjct: 390 NPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRS 449
Query: 473 TKNEDLWDSMASICPTDGVKGMD 495
+D D P K +D
Sbjct: 450 ILADDFLDFYLEYFPELKKKRVD 472
>gi|4505029 leukotriene A4 hydrolase [Homo sapiens]
Length = 611
Score = 89.0 bits (219), Expect = 2e-17
Identities = 98/443 (22%), Positives = 179/443 (40%), Gaps = 52/443 (11%)
Query: 62 HYDLLIHANLTTLTFWGTTKVEITASQPT-STIILHSHHLQISRATL-----RKGAGERL 115
H L + T T GT + + + + +++L + L I + + + GER
Sbjct: 21 HLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQ 80
Query: 116 SEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELR 175
S + + +I+L P+ + +VI + S T G+
Sbjct: 81 SYKGSPM-------EISL----PIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEH 129
Query: 176 ILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDH 235
+Q + R PC D P+ K +++ ++ +A+ + + +G D
Sbjct: 130 PYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMS-------AIRDGETPDP 182
Query: 236 FDVT---------VKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAA 286
D + V + YL+A ++ ES + G + V++ +++ ++ Y
Sbjct: 183 EDPSRKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSET 238
Query: 287 VTLLEFYEDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKL 345
++L+ ED PY + DL +P F G MEN LT + L D S+
Sbjct: 239 ESMLKIAEDLGG-PYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNV---- 293
Query: 346 GITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFME-FVSVSVTHPELKVGDYFFGKC 404
+AHE++H W GNLVT + W+ WLNEG ++E + + + + + G
Sbjct: 294 -----IAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWG 348
Query: 405 FDAMEVDALNSSHPVSTPVENPAQIRE--MFDDVSYDKGACILNMLREYLSA-DAFKSGI 461
V +HP + V + I + V Y+KG +L L + L + F +
Sbjct: 349 ELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFL 408
Query: 462 VQYLQKHSYKNTKNEDLWDSMAS 484
Y++K SYK+ +D D + S
Sbjct: 409 KAYVEKFSYKSITTDDWKDFLYS 431
>gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Homo
sapiens]
Length = 494
Score = 80.9 bits (198), Expect = 5e-15
Identities = 75/272 (27%), Positives = 113/272 (41%), Gaps = 45/272 (16%)
Query: 235 HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYE 294
HF + + YLVA + D K G + V+A P + A L AV
Sbjct: 16 HFHMEHPVPAYLVALVAGDL----KPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAA 71
Query: 295 DYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAH 353
+ PY + D+ +P F AMEN LT S L D + + V H
Sbjct: 72 ERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEF---------LVIDVIH 122
Query: 354 ELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAME---- 409
E+AH WFGN VT W ++WL+EG A T+ + ++ +G F +E
Sbjct: 123 EVAHSWFGNAVTNATWEEMWLSEGLA----------TYAQRRITTETYGAAFTCLETAFR 172
Query: 410 VDALN-------SSHPVS------TPVENPAQIREMFDDVSYDKGACILNMLREYL-SAD 455
+DAL+ PVS P NP+ + +F +Y+KG C + L +
Sbjct: 173 LDALHRQMKLLGEDSPVSKLQVKLEPGVNPSHLMNLF---TYEKGYCFVYYLSQLCGDPQ 229
Query: 456 AFKSGIVQYLQKHSYKNTKNEDLWDSMASICP 487
F + Y++K+ + + +DL DS S P
Sbjct: 230 RFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFP 261
>gi|4507347 TBP-associated factor 2 [Homo sapiens]
Length = 1199
Score = 42.7 bits (99), Expect = 0.002
Identities = 40/202 (19%), Positives = 87/202 (43%), Gaps = 14/202 (6%)
Query: 186 AARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED-HFDVTVKMST 244
+ R FPC D + ++ ++ + +A+SN LV++V + + H+ +T+ +
Sbjct: 185 STRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAA 244
Query: 245 YLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLP 304
++ I FE + + +V+ + +P + + + EFYE+ + YP
Sbjct: 245 SNISLAIGPFEIL--VDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYS 302
Query: 305 KQDLAAIPD--FQSGAMENWGL--TTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360
I + + A + + T SA++ D + +A LA Q+F
Sbjct: 303 CFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRC-------LAQSLAQQFF 355
Query: 361 GNLVTMEWWNDLWLNEGFAKFM 382
G ++ W+D W+ +G + ++
Sbjct: 356 GCFISRMSWSDEWVLKGISGYI 377
>gi|110825988 TAR RNA binding protein 1 [Homo sapiens]
Length = 1621
Score = 31.6 bits (70), Expect = 3.6
Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 606 GYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLK 665
G + Y D W L+ LLK HT + + + ++ V + +++ AL+ +L +
Sbjct: 882 GKIVAQYIHDQWVCLSFLLKKYHTLIPTTG-SEILEPFLPAVQMPIRTLQSALE-ALTVL 939
Query: 666 HETEIMPVFQGLNELIP 682
+++PVF L L+P
Sbjct: 940 SSDQVLPVFHCLKVLVP 956
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,753,679
Number of Sequences: 37866
Number of extensions: 1476476
Number of successful extensions: 3455
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3376
Number of HSP's gapped (non-prelim): 21
length of query: 941
length of database: 18,247,518
effective HSP length: 112
effective length of query: 829
effective length of database: 14,006,526
effective search space: 11611410054
effective search space used: 11611410054
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.