Guide to the Human Genome
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Search of human proteins with 90652853

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform
a [Homo sapiens]
         (565 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform ...  1174   0.0  
gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform ...  1174   0.0  
gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform ...  1091   0.0  
gi|4506325 protein tyrosine phosphatase, receptor type, R isofor...   410   e-114
gi|19743917 protein tyrosine phosphatase, receptor type, R isofo...   407   e-113
gi|18375660 protein tyrosine phosphatase, non-receptor type 7 is...   332   4e-91
gi|18375658 protein tyrosine phosphatase, non-receptor type 7 is...   332   6e-91
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo...   189   8e-48
gi|148539860 protein tyrosine phosphatase, receptor type, T isof...   189   8e-48
gi|148539858 protein tyrosine phosphatase, receptor type, T isof...   189   8e-48
gi|157419150 protein tyrosine phosphatase, receptor type, M isof...   182   5e-46
gi|157419152 protein tyrosine phosphatase, receptor type, M isof...   182   5e-46
gi|208431815 protein tyrosine phosphatase, receptor type, K isof...   182   7e-46
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   180   3e-45
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   180   3e-45
gi|194097398 protein tyrosine phosphatase, receptor type, G prec...   175   1e-43
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is...   175   1e-43
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is...   175   1e-43
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is...   175   1e-43
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [...   174   2e-43
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ...   174   3e-43
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...   174   3e-43
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ...   174   3e-43
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ...   174   3e-43
gi|104487002 protein tyrosine phosphatase, receptor type, D isof...   173   4e-43
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...   173   4e-43
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo...   173   4e-43
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...   173   4e-43
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo...   173   4e-43
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p...   171   2e-42

>gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform a
           [Homo sapiens]
          Length = 565

 Score = 1174 bits (3036), Expect = 0.0
 Identities = 565/565 (100%), Positives = 565/565 (100%)

Query: 1   MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
           MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
Sbjct: 1   MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60

Query: 61  PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV 120
           PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
Sbjct: 61  PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV 120

Query: 121 SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 180
           SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
Sbjct: 121 SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 180

Query: 181 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 240
           RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
Sbjct: 181 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 240

Query: 241 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 300
           ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
Sbjct: 241 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 300

Query: 301 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 360
           QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
Sbjct: 301 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 360

Query: 361 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 420
           GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
Sbjct: 361 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 420

Query: 421 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 480
           GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
Sbjct: 421 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 480

Query: 481 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 540
           AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
Sbjct: 481 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 540

Query: 541 TCEQYQFVHHVMSLYEKQLSHQSPE 565
           TCEQYQFVHHVMSLYEKQLSHQSPE
Sbjct: 541 TCEQYQFVHHVMSLYEKQLSHQSPE 565


>gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform a
           [Homo sapiens]
          Length = 565

 Score = 1174 bits (3036), Expect = 0.0
 Identities = 565/565 (100%), Positives = 565/565 (100%)

Query: 1   MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
           MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
Sbjct: 1   MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60

Query: 61  PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV 120
           PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
Sbjct: 61  PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV 120

Query: 121 SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 180
           SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
Sbjct: 121 SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 180

Query: 181 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 240
           RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
Sbjct: 181 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 240

Query: 241 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 300
           ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
Sbjct: 241 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 300

Query: 301 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 360
           QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
Sbjct: 301 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 360

Query: 361 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 420
           GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
Sbjct: 361 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 420

Query: 421 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 480
           GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
Sbjct: 421 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 480

Query: 481 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 540
           AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
Sbjct: 481 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 540

Query: 541 TCEQYQFVHHVMSLYEKQLSHQSPE 565
           TCEQYQFVHHVMSLYEKQLSHQSPE
Sbjct: 541 TCEQYQFVHHVMSLYEKQLSHQSPE 565


>gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform b
           [Homo sapiens]
          Length = 533

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 533/565 (94%), Positives = 533/565 (94%), Gaps = 32/565 (5%)

Query: 1   MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
           MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
Sbjct: 1   MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60

Query: 61  PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV 120
           PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFL                       
Sbjct: 61  PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFL----------------------- 97

Query: 121 SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 180
                    LEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
Sbjct: 98  ---------LEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 148

Query: 181 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 240
           RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
Sbjct: 149 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 208

Query: 241 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 300
           ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
Sbjct: 209 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 268

Query: 301 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 360
           QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
Sbjct: 269 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 328

Query: 361 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 420
           GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
Sbjct: 329 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 388

Query: 421 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 480
           GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
Sbjct: 389 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 448

Query: 481 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 540
           AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
Sbjct: 449 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 508

Query: 541 TCEQYQFVHHVMSLYEKQLSHQSPE 565
           TCEQYQFVHHVMSLYEKQLSHQSPE
Sbjct: 509 TCEQYQFVHHVMSLYEKQLSHQSPE 533


>gi|4506325 protein tyrosine phosphatase, receptor type, R isoform 1
           precursor [Homo sapiens]
          Length = 657

 Score =  410 bits (1054), Expect = e-114
 Identities = 226/445 (50%), Positives = 291/445 (65%), Gaps = 28/445 (6%)

Query: 135 WLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPE-DRRQSVSRQPSFTY 193
           W   G + V    ++FLS+ +++VT L+  L R        L  + ++ Q +   P    
Sbjct: 223 WSKEGFYAV----VIFLSIFVIIVTCLMI-LYRLKERFQLSLRQDKEKNQEIHLSPITLQ 277

Query: 194 SEWMEEKIEDDFLDLDPVPETPVFDCVMDIK----PEADPTSLT--------VKSMGLQE 241
               E K     +  +  P+  V + V+D +    PE   T+ T        +K +GLQE
Sbjct: 278 PALSEAKTVHSMVQPEQAPK--VLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQE 335

Query: 242 RRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQ 301
           RRGSNVSLTLDM + G N E F  + +PRE+ A EYL SASR+L   +L +      LLQ
Sbjct: 336 RRGSNVSLTLDMSSLG-NIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQ 394

Query: 302 AEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRG 361
           +EF EIPMNFVDPKE DIP    KNRYKTILPNP SRVCL   +  D LS+YINANYIRG
Sbjct: 395 SEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRG 454

Query: 362 YGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDG 421
           Y G+EK +IATQGP+++TV DFW+MVWQE +P+IVMIT ++E NEKC  YWPE++  Y  
Sbjct: 455 YSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGK 514

Query: 422 VEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE- 480
           VE+ V  V   ++Y +R + LK G+  + +KHYW+TSWPD KTPD A PLL L+ +VEE 
Sbjct: 515 VEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEED 574

Query: 481 --AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGM 538
             A+Q  G    P++VHCSAGIGRTGCFIATSI CQQL++EGVVD L   CQLR DRGGM
Sbjct: 575 RLASQGRG----PVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGM 630

Query: 539 IQTCEQYQFVHHVMSLYEKQLSHQS 563
           +QT EQY+FVHH + LYE +LS ++
Sbjct: 631 VQTSEQYEFVHHALCLYESRLSAET 655


>gi|19743917 protein tyrosine phosphatase, receptor type, R isoform
           2 [Homo sapiens]
          Length = 412

 Score =  407 bits (1045), Expect = e-113
 Identities = 203/338 (60%), Positives = 250/338 (73%), Gaps = 8/338 (2%)

Query: 229 PTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAE 288
           P+   +K +GLQERRGSNVSLTLDM + G N E F  + +PRE+ A EYL SASR+L   
Sbjct: 78  PSPFKMKPIGLQERRGSNVSLTLDMSSLG-NIEPFVSIPTPREKVAMEYLQSASRILTRS 136

Query: 289 ELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDD 348
           +L +      LLQ+EF EIPMNFVDPKE DIP    KNRYKTILPNP SRVCL   +  D
Sbjct: 137 QLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTD 196

Query: 349 PLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKC 408
            LS+YINANYIRGY G+EK +IATQGP+++TV DFW+MVWQE +P+IVMIT ++E NEKC
Sbjct: 197 SLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKC 256

Query: 409 TEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRA 468
             YWPE++  Y  VE+ V  V   ++Y +R + LK G+  + +KHYW+TSWPD KTPD A
Sbjct: 257 VLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSA 316

Query: 469 PPLLHLVREVEE---AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDIL 525
            PLL L+ +VEE   A+Q  G    P++VHCSAGIGRTGCFIATSI CQQL++EGVVD L
Sbjct: 317 QPLLQLMLDVEEDRLASQGRG----PVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDAL 372

Query: 526 KTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQS 563
              CQLR DRGGM+QT EQY+FVHH + LYE +LS ++
Sbjct: 373 SIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAET 410


>gi|18375660 protein tyrosine phosphatase, non-receptor type 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score =  332 bits (852), Expect = 4e-91
 Identities = 184/401 (45%), Positives = 238/401 (59%), Gaps = 26/401 (6%)

Query: 177 PPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTV-- 234
           P    R+   R  SF  + W+ E        L P P   +       +  A P +L++  
Sbjct: 7   PIRQAREQQRRALSFRQTSWLSEP------PLGPAPHLSMVQAHGG-RSRAQPLTLSLGA 59

Query: 235 -------------KSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSA 281
                        K + LQERRGSNV+L LD+ + G  E     + +PRE +   +L +A
Sbjct: 60  AMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTA 117

Query: 282 SRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCL 341
              L    L  +   P  L+ EF +IP NFV P++ DIPG   K+RYKTILPNP SRVCL
Sbjct: 118 GHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCL 177

Query: 342 TSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI 401
                 +    YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE   +IVM+T +
Sbjct: 178 GRAQSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL 236

Query: 402 EEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPD 461
            E  EKC  YWP E+  Y   +I +Q +    +Y +R ++++   E R +KH  F++WPD
Sbjct: 237 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD 296

Query: 462 QKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGV 521
            +TP+ A PLL LV EVEE + +   H  PI+VHCSAGIGRTGCFIAT I CQQL+  G 
Sbjct: 297 HQTPESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE 355

Query: 522 VDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 562
           VDIL   CQLR DRGGMIQT EQYQF+HH ++LY  QL  +
Sbjct: 356 VDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 396


>gi|18375658 protein tyrosine phosphatase, non-receptor type 7
           isoform 1 [Homo sapiens]
          Length = 360

 Score =  332 bits (851), Expect = 6e-91
 Identities = 174/338 (51%), Positives = 220/338 (65%), Gaps = 7/338 (2%)

Query: 225 PEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRV 284
           PE  P     K + LQERRGSNV+L LD+ + G  E     + +PRE +   +L +A   
Sbjct: 27  PEKTPAK---KHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTAGHP 81

Query: 285 LQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSP 344
           L    L  +   P  L+ EF +IP NFV P++ DIPG   K+RYKTILPNP SRVCL   
Sbjct: 82  LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA 141

Query: 345 DPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM 404
              +    YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE   +IVM+T + E 
Sbjct: 142 QSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG 200

Query: 405 NEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKT 464
            EKC  YWP E+  Y   +I +Q +    +Y +R ++++   E R +KH  F++WPD +T
Sbjct: 201 KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQT 260

Query: 465 PDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDI 524
           P+ A PLL LV EVEE + +   H  PI+VHCSAGIGRTGCFIAT I CQQL+  G VDI
Sbjct: 261 PESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDI 319

Query: 525 LKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 562
           L   CQLR DRGGMIQT EQYQF+HH ++LY  QL  +
Sbjct: 320 LGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 357


>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
            [Homo sapiens]
          Length = 1440

 Score =  189 bits (479), Expect = 8e-48
 Identities = 104/228 (45%), Positives = 132/228 (57%), Gaps = 8/228 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  I+   HSRV L  P  DDP S YINANYI GY      YIATQGP+  TV DFW
Sbjct: 914  KNRYGNIIAYDHSRVIL-QPVEDDPSSDYINANYIDGYQRPSH-YIATQGPVHETVYDFW 971

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 442
            RM+WQE +  IVM+TN+ E+   KC +YWP++   Y   ++T  ++    +Y +R  +L 
Sbjct: 972  RMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLE 1031

Query: 443  -KSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 501
             +   E R +K + FT WPD   P  A  LL  +R V+ +     P   PI+VHCSAG G
Sbjct: 1032 RRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLS---NPPSAGPIVVHCSAGAG 1088

Query: 502  RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 549
            RTGC+I   I      +EGVVDI      LR  R  M+QT EQY F+H
Sbjct: 1089 RTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIH 1136



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 65/237 (27%), Positives = 115/237 (48%), Gaps = 10/237 (4%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR+  +LP       L + D +   S+YINA  +  Y  +   +I TQ P+ +TV DFW
Sbjct: 1204 KNRFMDMLPPDRCLPFLITIDGES--SNYINAALMDSYR-QPAAFIVTQYPLPNTVKDFW 1260

Query: 385  RMVWQEHTPIIVMITNIEEMNEKCTEYWPEE-QVAYDGVEITVQKVIHTEDYRLRLISLK 443
            R+V+      IVM+  ++ +++ C +YWPEE  + Y  +++         D   R+  + 
Sbjct: 1261 RLVYDYGCTSIVMLNEVD-LSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRIC 1319

Query: 444  SGTEERG----LKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSA 498
            + T  +     ++ + +  W   +  P      L L+ +VE+  ++        I+HC  
Sbjct: 1320 NLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLN 1379

Query: 499  GIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY 555
            G GR+G F A  I  + ++++ VVD+      LR  +  M++  EQY+F + V   Y
Sbjct: 1380 GGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEY 1436


>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
            precursor [Homo sapiens]
          Length = 1441

 Score =  189 bits (479), Expect = 8e-48
 Identities = 107/228 (46%), Positives = 135/228 (59%), Gaps = 8/228 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  I+   HSRV L   D  DP S YINANYI GY    + YIATQGP+  TV DFW
Sbjct: 915  KNRYGNIISYDHSRVRLLVLD-GDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 972

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 442
            RM+WQE++  IVM+TN+ E+   KC  YWP++   Y  +++T+ +     +Y +R  ++ 
Sbjct: 973  RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1032

Query: 443  KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 501
            K G  E R L+ + FTSWPD   P  A  LL  VR+V+       P   PI+VHCSAG G
Sbjct: 1033 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFL---NPPEAGPIVVHCSAGAG 1089

Query: 502  RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 549
            RTGCFIA          EGVVDI     +LR  R  ++QT EQY FVH
Sbjct: 1090 RTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVH 1137



 Score =  112 bits (279), Expect = 1e-24
 Identities = 75/253 (29%), Positives = 126/253 (49%), Gaps = 13/253 (5%)

Query: 312  VDPKEYDIPGLVR---KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKV 368
            V P++  I  L R   KNR   +LP       L S D +   S+YINA  +  +  +   
Sbjct: 1189 VRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES--SNYINAALMDSHK-QPAA 1245

Query: 369  YIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVA-YDGVEITVQ 427
            ++ TQ P+ +TVADFWR+V+  +   +VM+  ++   + C +YWPE+    Y  +++   
Sbjct: 1246 FVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTA-QFCMQYWPEKTSGCYGPIQVEFV 1304

Query: 428  KVIHTEDYRLRLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAA 482
                 ED   R+  + +        R ++H  +  WP  + TP     LL +VR +E+  
Sbjct: 1305 SADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQ 1364

Query: 483  QQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTC 542
            +Q        +VHC  G GR+G F A    C+ ++Q+ ++D+      LR ++  M++T 
Sbjct: 1365 EQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETL 1424

Query: 543  EQYQFVHHVMSLY 555
            EQY+FV+ V   Y
Sbjct: 1425 EQYKFVYEVALEY 1437


>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
            precursor [Homo sapiens]
          Length = 1460

 Score =  189 bits (479), Expect = 8e-48
 Identities = 107/228 (46%), Positives = 135/228 (59%), Gaps = 8/228 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  I+   HSRV L   D  DP S YINANYI GY    + YIATQGP+  TV DFW
Sbjct: 934  KNRYGNIISYDHSRVRLLVLD-GDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 991

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 442
            RM+WQE++  IVM+TN+ E+   KC  YWP++   Y  +++T+ +     +Y +R  ++ 
Sbjct: 992  RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1051

Query: 443  KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 501
            K G  E R L+ + FTSWPD   P  A  LL  VR+V+       P   PI+VHCSAG G
Sbjct: 1052 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFL---NPPEAGPIVVHCSAGAG 1108

Query: 502  RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 549
            RTGCFIA          EGVVDI     +LR  R  ++QT EQY FVH
Sbjct: 1109 RTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVH 1156



 Score =  112 bits (279), Expect = 1e-24
 Identities = 75/253 (29%), Positives = 126/253 (49%), Gaps = 13/253 (5%)

Query: 312  VDPKEYDIPGLVR---KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKV 368
            V P++  I  L R   KNR   +LP       L S D +   S+YINA  +  +  +   
Sbjct: 1208 VRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES--SNYINAALMDSHK-QPAA 1264

Query: 369  YIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVA-YDGVEITVQ 427
            ++ TQ P+ +TVADFWR+V+  +   +VM+  ++   + C +YWPE+    Y  +++   
Sbjct: 1265 FVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTA-QFCMQYWPEKTSGCYGPIQVEFV 1323

Query: 428  KVIHTEDYRLRLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAA 482
                 ED   R+  + +        R ++H  +  WP  + TP     LL +VR +E+  
Sbjct: 1324 SADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQ 1383

Query: 483  QQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTC 542
            +Q        +VHC  G GR+G F A    C+ ++Q+ ++D+      LR ++  M++T 
Sbjct: 1384 EQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETL 1443

Query: 543  EQYQFVHHVMSLY 555
            EQY+FV+ V   Y
Sbjct: 1444 EQYKFVYEVALEY 1456


>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
            precursor [Homo sapiens]
          Length = 1452

 Score =  182 bits (463), Expect = 5e-46
 Identities = 100/228 (43%), Positives = 134/228 (58%), Gaps = 8/228 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  I+   HSRV L + + D   S YIN NYI GY      YIATQGP+  T+ DFW
Sbjct: 926  KNRYGNIIAYDHSRVRLQTIEGDTN-SDYINGNYIDGYHRPNH-YIATQGPMQETIYDFW 983

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 442
            RMVW E+T  I+M+TN+ E+   KC +YWP++   Y  +++T+ +     +Y +R  ++ 
Sbjct: 984  RMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVE 1043

Query: 443  KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 501
            K G  E R ++ + FT WPD   P  A  LL  VR+V+  +    P   P++VHCSAG G
Sbjct: 1044 KRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSP---PSAGPLVVHCSAGAG 1100

Query: 502  RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 549
            RTGCFI   I      +EGVVDI     +LR  R  M+QT EQY F+H
Sbjct: 1101 RTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIH 1148



 Score =  111 bits (277), Expect = 2e-24
 Identities = 73/243 (30%), Positives = 117/243 (48%), Gaps = 10/243 (4%)

Query: 319  IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS 378
            +P    KNR   ILP       L + D +   S+YINA  +  Y  +   +I TQ P+ +
Sbjct: 1210 LPRNHEKNRCMDILPPDRCLPFLITIDGES--SNYINAALMDSYK-QPSAFIVTQHPLPN 1266

Query: 379  TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDG-VEITVQKVIHTEDYRL 437
            TV DFWR+V   H   +VM+ +++   + C +YWPE  V   G +++        ED   
Sbjct: 1267 TVKDFWRLVLDYHCTSVVMLNDVDPA-QLCPQYWPENGVHRHGPIQVEFVSADLEEDIIS 1325

Query: 438  RLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPI 492
            R+  + +        R ++ + F  WP  + TP      L L+R+V++  ++        
Sbjct: 1326 RIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRT 1385

Query: 493  IVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            +VHC  G GR+G F A SI C+ LR +  VD+      LR ++  M+   +QY+F + V 
Sbjct: 1386 VVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVA 1445

Query: 553  SLY 555
              Y
Sbjct: 1446 LEY 1448


>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
            precursor [Homo sapiens]
          Length = 1465

 Score =  182 bits (463), Expect = 5e-46
 Identities = 100/228 (43%), Positives = 134/228 (58%), Gaps = 8/228 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  I+   HSRV L + + D   S YIN NYI GY      YIATQGP+  T+ DFW
Sbjct: 939  KNRYGNIIAYDHSRVRLQTIEGDTN-SDYINGNYIDGYHRPNH-YIATQGPMQETIYDFW 996

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 442
            RMVW E+T  I+M+TN+ E+   KC +YWP++   Y  +++T+ +     +Y +R  ++ 
Sbjct: 997  RMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVE 1056

Query: 443  KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 501
            K G  E R ++ + FT WPD   P  A  LL  VR+V+  +    P   P++VHCSAG G
Sbjct: 1057 KRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSP---PSAGPLVVHCSAGAG 1113

Query: 502  RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 549
            RTGCFI   I      +EGVVDI     +LR  R  M+QT EQY F+H
Sbjct: 1114 RTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIH 1161



 Score =  111 bits (277), Expect = 2e-24
 Identities = 73/243 (30%), Positives = 117/243 (48%), Gaps = 10/243 (4%)

Query: 319  IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS 378
            +P    KNR   ILP       L + D +   S+YINA  +  Y  +   +I TQ P+ +
Sbjct: 1223 LPRNHEKNRCMDILPPDRCLPFLITIDGES--SNYINAALMDSYK-QPSAFIVTQHPLPN 1279

Query: 379  TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDG-VEITVQKVIHTEDYRL 437
            TV DFWR+V   H   +VM+ +++   + C +YWPE  V   G +++        ED   
Sbjct: 1280 TVKDFWRLVLDYHCTSVVMLNDVDPA-QLCPQYWPENGVHRHGPIQVEFVSADLEEDIIS 1338

Query: 438  RLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPI 492
            R+  + +        R ++ + F  WP  + TP      L L+R+V++  ++        
Sbjct: 1339 RIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRT 1398

Query: 493  IVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            +VHC  G GR+G F A SI C+ LR +  VD+      LR ++  M+   +QY+F + V 
Sbjct: 1399 VVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVA 1458

Query: 553  SLY 555
              Y
Sbjct: 1459 LEY 1461


>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
            [Homo sapiens]
          Length = 1446

 Score =  182 bits (462), Expect = 7e-46
 Identities = 104/234 (44%), Positives = 132/234 (56%), Gaps = 14/234 (5%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR------GYGGEEKVYIATQGPIVS 378
            KNRY  I+   HSRV L  P  DDP S YINANYI       GY      YIATQGP+  
Sbjct: 914  KNRYGNIIAYDHSRVIL-QPVEDDPSSDYINANYIDIWLYRDGYQRPSH-YIATQGPVHE 971

Query: 379  TVADFWRMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRL 437
            TV DFWRM+WQE +  IVM+TN+ E+   KC +YWP++   Y   ++T  ++    +Y +
Sbjct: 972  TVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVV 1031

Query: 438  RLISL--KSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVH 495
            R  +L  +   E R +K + FT WPD   P  A  LL  +R V+ +     P   PI+VH
Sbjct: 1032 RTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLS---NPPSAGPIVVH 1088

Query: 496  CSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 549
            CSAG GRTGC+I   I      +EGVVDI      LR  R  M+QT EQY F+H
Sbjct: 1089 CSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIH 1142



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 65/237 (27%), Positives = 115/237 (48%), Gaps = 10/237 (4%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR+  +LP       L + D +   S+YINA  +  Y  +   +I TQ P+ +TV DFW
Sbjct: 1210 KNRFMDMLPPDRCLPFLITIDGES--SNYINAALMDSYR-QPAAFIVTQYPLPNTVKDFW 1266

Query: 385  RMVWQEHTPIIVMITNIEEMNEKCTEYWPEE-QVAYDGVEITVQKVIHTEDYRLRLISLK 443
            R+V+      IVM+  ++ +++ C +YWPEE  + Y  +++         D   R+  + 
Sbjct: 1267 RLVYDYGCTSIVMLNEVD-LSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRIC 1325

Query: 444  SGTEERG----LKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSA 498
            + T  +     ++ + +  W   +  P      L L+ +VE+  ++        I+HC  
Sbjct: 1326 NLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLN 1385

Query: 499  GIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY 555
            G GR+G F A  I  + ++++ VVD+      LR  +  M++  EQY+F + V   Y
Sbjct: 1386 GGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEY 1442


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  180 bits (457), Expect = 3e-45
 Identities = 96/232 (41%), Positives = 138/232 (59%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV LTS D   P S YINANYI GY  ++  YIATQGP+  T+ DFW
Sbjct: 1378 KNRYANVIAYDHSRVILTSID-GVPGSDYINANYIDGYR-KQNAYIATQGPLPETMGDFW 1435

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 442
            RMVW++ T  +VM+T +EE +  KC +YWP       G +++T+   +    Y +R  +L
Sbjct: 1436 RMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFAL 1495

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             KSG+ E+R L+ + F +WPD   P+   P+L  +R V+     +     P++VHCSAG+
Sbjct: 1496 HKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA---GPMVVHCSAGV 1552

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VDI      +R  R  M+QT +QY F+H  +
Sbjct: 1553 GRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1604



 Score =  167 bits (424), Expect = 2e-41
 Identities = 94/241 (39%), Positives = 133/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA+++ GY  ++K YIATQGP+  +  DFW
Sbjct: 1667 KNRLVNIMPYELTRVCL-QPIRGVEGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFW 1724

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ IIVM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1725 RMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1784

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1785 TDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD-GPITVHCSAGV 1843

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVD+ +T   LR  R  M+QT +QYQ  +     Y     
Sbjct: 1844 GRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1903

Query: 561  H 561
            H
Sbjct: 1904 H 1904


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  180 bits (457), Expect = 3e-45
 Identities = 96/232 (41%), Positives = 138/232 (59%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV LTS D   P S YINANYI GY  ++  YIATQGP+  T+ DFW
Sbjct: 1369 KNRYANVIAYDHSRVILTSID-GVPGSDYINANYIDGYR-KQNAYIATQGPLPETMGDFW 1426

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 442
            RMVW++ T  +VM+T +EE +  KC +YWP       G +++T+   +    Y +R  +L
Sbjct: 1427 RMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFAL 1486

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             KSG+ E+R L+ + F +WPD   P+   P+L  +R V+     +     P++VHCSAG+
Sbjct: 1487 HKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA---GPMVVHCSAGV 1543

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VDI      +R  R  M+QT +QY F+H  +
Sbjct: 1544 GRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1595



 Score =  167 bits (424), Expect = 2e-41
 Identities = 94/241 (39%), Positives = 133/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA+++ GY  ++K YIATQGP+  +  DFW
Sbjct: 1658 KNRLVNIMPYELTRVCL-QPIRGVEGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFW 1715

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ IIVM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1716 RMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1775

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1776 TDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD-GPITVHCSAGV 1834

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVD+ +T   LR  R  M+QT +QYQ  +     Y     
Sbjct: 1835 GRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1894

Query: 561  H 561
            H
Sbjct: 1895 H 1895


>gi|194097398 protein tyrosine phosphatase, receptor type, G precursor
            [Homo sapiens]
          Length = 1445

 Score =  175 bits (443), Expect = 1e-43
 Identities = 98/244 (40%), Positives = 135/244 (55%), Gaps = 20/244 (8%)

Query: 325  KNRYKTILPNPHSRVCLTS-PDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADF 383
            KNRY  IL   HSRV L   P  D   S YINANY+ GY  + K YIATQGP+ ST  DF
Sbjct: 877  KNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYN-KAKAYIATQGPLKSTFEDF 935

Query: 384  WRMVWQEHTPIIVMITN-IEEMNEKCTEYWP-EEQVAYDGVEITVQKVIHTEDYRLRLIS 441
            WRM+W+++T IIVMITN +E+   KC +YWP E    Y  + +T++       Y +R  S
Sbjct: 936  WRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFS 995

Query: 442  LKSGTEERGLK-------------HYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPH 488
            +++   ++G K              Y +T WPD   P+ A P+L  VR    A     P 
Sbjct: 996  IRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARM---PE 1052

Query: 489  CAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFV 548
              P++VHCSAG+GRTG +I      QQ++ +  V++L     +R  R  ++QT EQY F+
Sbjct: 1053 TGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFI 1112

Query: 549  HHVM 552
            H  +
Sbjct: 1113 HDAL 1116



 Score =  103 bits (256), Expect = 5e-22
 Identities = 70/238 (29%), Positives = 116/238 (48%), Gaps = 18/238 (7%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR  +++P+  +RV L +P P    + YINA+YI GY    + +I TQ P+  T  DFW
Sbjct: 1178 KNRNSSVVPSERARVGL-APLPGMKGTDYINASYIMGYYRSNE-FIITQHPLPHTTKDFW 1235

Query: 385  RMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKV------IHTEDYRLR 438
            RM+W  +  IIVM+ + + + E    YWP  + + +    TV  +      +  E+  + 
Sbjct: 1236 RMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIII 1295

Query: 439  LISLKSGTEE---RGLKHYWFTSWPDQKTPDRAP-PLLHLVREVEEAAQQEGPHCAPIIV 494
               +   T++     ++H+    WP+   P  +   L+++++  EEA  ++G    P IV
Sbjct: 1296 HDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIK--EEALTRDG----PTIV 1349

Query: 495  HCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            H   G    G   A +   QQL  E  VD+ +    +   R G+    EQYQF++  M
Sbjct: 1350 HDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKAM 1407


>gi|18104993 protein tyrosine phosphatase, non-receptor type 6
           isoform 3 [Homo sapiens]
          Length = 624

 Score =  175 bits (443), Expect = 1e-43
 Identities = 102/238 (42%), Positives = 138/238 (57%), Gaps = 14/238 (5%)

Query: 325 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGY--GGEE--KVYIATQGPIVSTV 380
           KNRYK ILP  HSRV L   D + P S YINANYI+    G +E  K YIA+QG + +TV
Sbjct: 273 KNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATV 332

Query: 381 ADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPE--EQVAYDGVEITVQKVIHTEDYRL 437
            DFW+M WQE++ +IVM T  +E+   KC  YWPE   Q AY    +T      T +Y+L
Sbjct: 333 NDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKL 392

Query: 438 RLIS---LKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIV 494
           R +    L +G   R + HY + SWPD   P     +L  + ++ +  Q+  PH  PIIV
Sbjct: 393 RTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQ-RQESLPHAGPIIV 451

Query: 495 HCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVH 549
           HCSAGIGRTG  I   +  + +  +G+   +DI KT   +R  R GM+QT  QY+F++
Sbjct: 452 HCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509


>gi|18104989 protein tyrosine phosphatase, non-receptor type 6
           isoform 1 [Homo sapiens]
          Length = 595

 Score =  175 bits (443), Expect = 1e-43
 Identities = 102/238 (42%), Positives = 138/238 (57%), Gaps = 14/238 (5%)

Query: 325 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGY--GGEE--KVYIATQGPIVSTV 380
           KNRYK ILP  HSRV L   D + P S YINANYI+    G +E  K YIA+QG + +TV
Sbjct: 273 KNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATV 332

Query: 381 ADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPE--EQVAYDGVEITVQKVIHTEDYRL 437
            DFW+M WQE++ +IVM T  +E+   KC  YWPE   Q AY    +T      T +Y+L
Sbjct: 333 NDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKL 392

Query: 438 RLIS---LKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIV 494
           R +    L +G   R + HY + SWPD   P     +L  + ++ +  Q+  PH  PIIV
Sbjct: 393 RTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQ-RQESLPHAGPIIV 451

Query: 495 HCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVH 549
           HCSAGIGRTG  I   +  + +  +G+   +DI KT   +R  R GM+QT  QY+F++
Sbjct: 452 HCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509


>gi|18104991 protein tyrosine phosphatase, non-receptor type 6
           isoform 2 [Homo sapiens]
          Length = 597

 Score =  175 bits (443), Expect = 1e-43
 Identities = 102/238 (42%), Positives = 138/238 (57%), Gaps = 14/238 (5%)

Query: 325 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGY--GGEE--KVYIATQGPIVSTV 380
           KNRYK ILP  HSRV L   D + P S YINANYI+    G +E  K YIA+QG + +TV
Sbjct: 275 KNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATV 334

Query: 381 ADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPE--EQVAYDGVEITVQKVIHTEDYRL 437
            DFW+M WQE++ +IVM T  +E+   KC  YWPE   Q AY    +T      T +Y+L
Sbjct: 335 NDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKL 394

Query: 438 RLIS---LKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIV 494
           R +    L +G   R + HY + SWPD   P     +L  + ++ +  Q+  PH  PIIV
Sbjct: 395 RTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQ-RQESLPHAGPIIV 453

Query: 495 HCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVH 549
           HCSAGIGRTG  I   +  + +  +G+   +DI KT   +R  R GM+QT  QY+F++
Sbjct: 454 HCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 511


>gi|33356177 protein tyrosine phosphatase, non-receptor type 11
           [Homo sapiens]
          Length = 593

 Score =  174 bits (441), Expect = 2e-43
 Identities = 103/257 (40%), Positives = 140/257 (54%), Gaps = 17/257 (6%)

Query: 325 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR-------GYGGEEKVYIATQGPIV 377
           KNRYK ILP  H+RV L   DP++P+S YINAN I             +K YIATQG + 
Sbjct: 276 KNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQ 335

Query: 378 STVADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPEEQV--AYDGVEITVQKVIHTED 434
           +TV DFWRMV+QE++ +IVM T  +E    KC +YWP+E     Y  + +   K     D
Sbjct: 336 NTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHD 395

Query: 435 YRLRLISLK---SGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAP 491
           Y LR + L     G  ER +  Y F +WPD   P     +L  + EV    Q+      P
Sbjct: 396 YTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHH-KQESIMDAGP 454

Query: 492 IIVHCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFV 548
           ++VHCSAGIGRTG FI   I    +R++GV   +D+ KT   +R  R GM+QT  QY+F+
Sbjct: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514

Query: 549 HHVMSLYEKQLSHQSPE 565
           +  +  Y + L  +  E
Sbjct: 515 YMAVQHYIETLQRRIEE 531


>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
            isoform 4 precursor [Homo sapiens]
          Length = 1505

 Score =  174 bits (440), Expect = 3e-43
 Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L  P      S YINANY+ GY  +   YIATQGP+  T  DFW
Sbjct: 976  KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1033

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 442
            RMVW++ +  IVM+T +EE +  KC +YWP      Y  +++T+   I    + +R  SL
Sbjct: 1034 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1093

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   PI+VHCSAG+
Sbjct: 1094 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1150

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VD+      +R  R  M+QT +QY F+H  +
Sbjct: 1151 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1202



 Score =  172 bits (436), Expect = 7e-43
 Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1265 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1322

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1323 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1382

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1383 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1441

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT ++YQF +     Y     
Sbjct: 1442 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1501

Query: 561  H 561
            H
Sbjct: 1502 H 1502


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
            isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score =  174 bits (440), Expect = 3e-43
 Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L  P      S YINANY+ GY  +   YIATQGP+  T  DFW
Sbjct: 1381 KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1438

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 442
            RMVW++ +  IVM+T +EE +  KC +YWP      Y  +++T+   I    + +R  SL
Sbjct: 1439 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1498

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   PI+VHCSAG+
Sbjct: 1499 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1555

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VD+      +R  R  M+QT +QY F+H  +
Sbjct: 1556 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1607



 Score =  172 bits (436), Expect = 7e-43
 Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1670 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1727

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1728 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1787

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1788 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1846

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT ++YQF +     Y     
Sbjct: 1847 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1906

Query: 561  H 561
            H
Sbjct: 1907 H 1907


>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
            isoform 3 precursor [Homo sapiens]
          Length = 1501

 Score =  174 bits (440), Expect = 3e-43
 Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L  P      S YINANY+ GY  +   YIATQGP+  T  DFW
Sbjct: 972  KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1029

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 442
            RMVW++ +  IVM+T +EE +  KC +YWP      Y  +++T+   I    + +R  SL
Sbjct: 1030 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1089

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   PI+VHCSAG+
Sbjct: 1090 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1146

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VD+      +R  R  M+QT +QY F+H  +
Sbjct: 1147 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1198



 Score =  172 bits (436), Expect = 7e-43
 Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1261 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1318

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1319 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1378

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1379 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1437

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT ++YQF +     Y     
Sbjct: 1438 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1497

Query: 561  H 561
            H
Sbjct: 1498 H 1498


>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
            isoform 1 precursor [Homo sapiens]
          Length = 1948

 Score =  174 bits (440), Expect = 3e-43
 Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L  P      S YINANY+ GY  +   YIATQGP+  T  DFW
Sbjct: 1419 KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1476

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 442
            RMVW++ +  IVM+T +EE +  KC +YWP      Y  +++T+   I    + +R  SL
Sbjct: 1477 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1536

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   PI+VHCSAG+
Sbjct: 1537 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1593

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VD+      +R  R  M+QT +QY F+H  +
Sbjct: 1594 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1645



 Score =  172 bits (436), Expect = 7e-43
 Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1708 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1765

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1766 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1825

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1826 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1884

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT ++YQF +     Y     
Sbjct: 1885 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1944

Query: 561  H 561
            H
Sbjct: 1945 H 1945


>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
            precursor [Homo sapiens]
          Length = 1502

 Score =  173 bits (438), Expect = 4e-43
 Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1262 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1319

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1320 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1379

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1380 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1438

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT +QYQF +     Y     
Sbjct: 1439 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1498

Query: 561  H 561
            H
Sbjct: 1499 H 1499



 Score =  172 bits (437), Expect = 6e-43
 Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L++ +   P S Y+NANYI GY  ++  YIATQG +  T  DFW
Sbjct: 973  KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1030

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 442
            RM+W++ +  +VM+T +EE +  KC +YWP       G V++T+   +    Y +R  +L
Sbjct: 1031 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1090

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   P++VHCSAG+
Sbjct: 1091 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1147

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VDI      +R  R  M+QT +QY F+H  +
Sbjct: 1148 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1199


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
            precursor [Homo sapiens]
          Length = 1912

 Score =  173 bits (438), Expect = 4e-43
 Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1672 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1729

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1730 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1789

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1790 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1848

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT +QYQF +     Y     
Sbjct: 1849 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1908

Query: 561  H 561
            H
Sbjct: 1909 H 1909



 Score =  172 bits (437), Expect = 6e-43
 Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L++ +   P S Y+NANYI GY  ++  YIATQG +  T  DFW
Sbjct: 1383 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1440

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 442
            RM+W++ +  +VM+T +EE +  KC +YWP       G V++T+   +    Y +R  +L
Sbjct: 1441 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1500

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   P++VHCSAG+
Sbjct: 1501 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1557

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VDI      +R  R  M+QT +QY F+H  +
Sbjct: 1558 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1609


>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
            precursor [Homo sapiens]
          Length = 1899

 Score =  173 bits (438), Expect = 4e-43
 Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1659 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1716

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1717 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1776

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1777 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1835

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT +QYQF +     Y     
Sbjct: 1836 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1895

Query: 561  H 561
            H
Sbjct: 1896 H 1896



 Score =  172 bits (437), Expect = 6e-43
 Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L++ +   P S Y+NANYI GY  ++  YIATQG +  T  DFW
Sbjct: 1370 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1427

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 442
            RM+W++ +  +VM+T +EE +  KC +YWP       G V++T+   +    Y +R  +L
Sbjct: 1428 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1487

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   P++VHCSAG+
Sbjct: 1488 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1544

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VDI      +R  R  M+QT +QY F+H  +
Sbjct: 1545 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1596


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
            precursor [Homo sapiens]
          Length = 1903

 Score =  173 bits (438), Expect = 4e-43
 Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1663 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1720

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1721 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1780

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1781 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1839

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT +QYQF +     Y     
Sbjct: 1840 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1899

Query: 561  H 561
            H
Sbjct: 1900 H 1900



 Score =  172 bits (437), Expect = 6e-43
 Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L++ +   P S Y+NANYI GY  ++  YIATQG +  T  DFW
Sbjct: 1374 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1431

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 442
            RM+W++ +  +VM+T +EE +  KC +YWP       G V++T+   +    Y +R  +L
Sbjct: 1432 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1491

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   P++VHCSAG+
Sbjct: 1492 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1548

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VDI      +R  R  M+QT +QY F+H  +
Sbjct: 1549 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1600


>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
            precursor [Homo sapiens]
          Length = 1501

 Score =  173 bits (438), Expect = 4e-43
 Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR   I+P   +RVCL  P      S YINA++I GY  ++K YIATQGP+  T  DFW
Sbjct: 1261 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1318

Query: 385  RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 442
            RM+W+ ++ I+VM+T + EM  EKC +YWP E+ A Y    +      +   Y LR   +
Sbjct: 1319 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1378

Query: 443  KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
                +   R ++ + FT WP+Q  P      +  + +V +  +Q G    PI VHCSAG+
Sbjct: 1379 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1437

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 560
            GRTG FI  SI  +++R EGVVDI +T   LR  R  M+QT +QYQF +     Y     
Sbjct: 1438 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1497

Query: 561  H 561
            H
Sbjct: 1498 H 1498



 Score =  172 bits (437), Expect = 6e-43
 Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNRY  ++   HSRV L++ +   P S Y+NANYI GY  ++  YIATQG +  T  DFW
Sbjct: 972  KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1029

Query: 385  RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 442
            RM+W++ +  +VM+T +EE +  KC +YWP       G V++T+   +    Y +R  +L
Sbjct: 1030 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1089

Query: 443  -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 500
             K+G+ E+R ++ + FT+WPD   P+   P L  +R V+       P   P++VHCSAG+
Sbjct: 1090 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1146

Query: 501  GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            GRTGCFI      ++++ E  VDI      +R  R  M+QT +QY F+H  +
Sbjct: 1147 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1198


>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
            precursor [Homo sapiens]
          Length = 2315

 Score =  171 bits (432), Expect = 2e-42
 Identities = 95/246 (38%), Positives = 135/246 (54%), Gaps = 17/246 (6%)

Query: 320  PGLVRKNRYKTILPNPHSRVCLTS-PDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS 378
            P    KNRY  I+   HSRV L    + D  L+ YINANY+ GY    K YIA QGP+ S
Sbjct: 1748 PDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDYINANYVDGYN-RPKAYIAAQGPLKS 1806

Query: 379  TVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEEQVAYDGVEITVQKVIHT----- 432
            T  DFWRM+W+ +  +IVMITN +E+   KC +YWP +     G  +  QK +       
Sbjct: 1807 TAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYT 1866

Query: 433  -EDYRLRLISLKSGTEE-----RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEG 486
              ++ LR   +K G+++     R +  Y +T WPD   P+ + P+L  VR+   AA  + 
Sbjct: 1867 VRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLTFVRK---AAYAKR 1923

Query: 487  PHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQ 546
                P++VHCSAG+GRTG +I      QQ++ EG V+I      +R  R  ++QT EQY 
Sbjct: 1924 HAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYV 1983

Query: 547  FVHHVM 552
            F+H  +
Sbjct: 1984 FIHDTL 1989



 Score =  108 bits (270), Expect = 1e-23
 Identities = 72/238 (30%), Positives = 124/238 (52%), Gaps = 19/238 (7%)

Query: 325  KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 384
            KNR  +I+P   SRV ++S   +   + YINA+YI GY  +   +I TQ P++ T+ DFW
Sbjct: 2051 KNRTSSIIPVERSRVGISSLSGEG--TDYINASYIMGYY-QSNEFIITQHPLLHTIKDFW 2107

Query: 385  RMVWQEHTPIIVMITNIEEMNEKCTEYWP--EEQVAYDGVEITV----QKVIHTEDYRLR 438
            RM+W  +  ++VMI + + M E    YWP  +E +  +  ++T+     K +  E+  + 
Sbjct: 2108 RMIWDHNAQLVVMIPDGQNMAEDEFVYWPNKDEPINCESFKVTLMAEEHKCLSNEEKLII 2167

Query: 439  LISLKSGTEE---RGLKHYWFTSWPDQKTP-DRAPPLLHLVREVEEAAQQEGPHCAPIIV 494
               +   T++     ++H+    WP+  +P  +   L+ +++  EEAA ++G    P+IV
Sbjct: 2168 QDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIK--EEAANRDG----PMIV 2221

Query: 495  HCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 552
            H   G    G F A +    QL +E  VD+ +    +   R G+    EQYQF++ V+
Sbjct: 2222 HDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVI 2279


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,094,106
Number of Sequences: 37866
Number of extensions: 1528080
Number of successful extensions: 24022
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 376
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 15628
Number of HSP's gapped (non-prelim): 5884
length of query: 565
length of database: 18,247,518
effective HSP length: 108
effective length of query: 457
effective length of database: 14,157,990
effective search space: 6470201430
effective search space used: 6470201430
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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