Search of human proteins with 89357938

Search of human proteins with 89357938

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo
sapiens]
         (161 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo sa...   337   3e-93
gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo sap...   335   1e-92
gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo sa...   241   2e-64
gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo sa...   101   2e-22
gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]         82   2e-16
gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo s...    72   2e-13
gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo sa...    72   2e-13
gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo sa...    72   2e-13
gi|119964726 insulin-like growth factor 2 receptor precursor [Ho...    29   2.0  
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]    29   2.0  
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]              28   4.5  
gi|30425382 signal-regulatory protein delta [Homo sapiens]             27   5.8  

>gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo
           sapiens]
          Length = 161

 Score =  337 bits (864), Expect = 3e-93
 Identities = 161/161 (100%), Positives = 161/161 (100%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60

Query: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLN 120
           WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLN
Sbjct: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLN 120

Query: 121 FGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASG 161
           FGSCT PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASG
Sbjct: 121 FGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASG 161


>gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo
           sapiens]
          Length = 249

 Score =  335 bits (858), Expect = 1e-92
 Identities = 160/160 (100%), Positives = 160/160 (100%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60

Query: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLN 120
           WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLN
Sbjct: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLN 120

Query: 121 FGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160
           FGSCT PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS
Sbjct: 121 FGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160


>gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo
           sapiens]
          Length = 201

 Score =  241 bits (615), Expect = 2e-64
 Identities = 112/112 (100%), Positives = 112/112 (100%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60

Query: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ 112
           WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ
Sbjct: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ 112


>gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo
          sapiens]
          Length = 185

 Score =  101 bits (252), Expect = 2e-22
 Identities = 49/49 (100%), Positives = 49/49 (100%)

Query: 1  MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG 49
          MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG
Sbjct: 1  MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG 49



 Score = 98.2 bits (243), Expect = 3e-21
 Identities = 48/48 (100%), Positives = 48/48 (100%)

Query: 113 GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160
           GNRPLVLNFGSCT PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS
Sbjct: 49  GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 96


>gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]
          Length = 278

 Score = 82.4 bits (202), Expect = 2e-16
 Identities = 49/105 (46%), Positives = 62/105 (59%), Gaps = 4/105 (3%)

Query: 57  SHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSG-QRCNIWEFMQGNR 115
           S DN + T  S +  W   K+ + +       GG APN  VV   G Q  +I ++ QGNR
Sbjct: 77  SDDNRLCTLASLKAVWHGQKLDFFK---QAHEGGPAPNSEVVLPDGFQSQHILDYAQGNR 133

Query: 116 PLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160
           PLVLNFGSCT P FM +   F+RL+  +    DFL+IYIEEAH S
Sbjct: 134 PLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPS 178


>gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo
           sapiens]
          Length = 309

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 39/92 (42%), Positives = 54/92 (58%), Gaps = 18/92 (19%)

Query: 87  ELGGLAPNCPVVRLS------------------GQRCNIWEFMQGNRPLVLNFGSCTUPS 128
           +LG  APN  VV +S                  G  C++ +F    RPLV+NFGS T P 
Sbjct: 112 KLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPP 171

Query: 129 FMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160
           F  +   F++L+E+FSS+ADFL++YI+EAH S
Sbjct: 172 FTSQLPAFRKLVEEFSSVADFLLVYIDEAHPS 203


>gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo
           sapiens]
          Length = 273

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 39/92 (42%), Positives = 54/92 (58%), Gaps = 18/92 (19%)

Query: 87  ELGGLAPNCPVVRLS------------------GQRCNIWEFMQGNRPLVLNFGSCTUPS 128
           +LG  APN  VV +S                  G  C++ +F    RPLV+NFGS T P 
Sbjct: 76  KLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPP 135

Query: 129 FMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160
           F  +   F++L+E+FSS+ADFL++YI+EAH S
Sbjct: 136 FTSQLPAFRKLVEEFSSVADFLLVYIDEAHPS 167


>gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo
           sapiens]
          Length = 273

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 39/92 (42%), Positives = 54/92 (58%), Gaps = 18/92 (19%)

Query: 87  ELGGLAPNCPVVRLS------------------GQRCNIWEFMQGNRPLVLNFGSCTUPS 128
           +LG  APN  VV +S                  G  C++ +F    RPLV+NFGS T P 
Sbjct: 76  KLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPP 135

Query: 129 FMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160
           F  +   F++L+E+FSS+ADFL++YI+EAH S
Sbjct: 136 FTSQLPAFRKLVEEFSSVADFLLVYIDEAHPS 167


>gi|119964726 insulin-like growth factor 2 receptor precursor [Homo
            sapiens]
          Length = 2491

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 4/58 (6%)

Query: 95   CPVVRLSGQRCNIWEFMQGN----RPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIAD 148
            CPVVR+ G  C + +   GN    +PL LN    +   + + F    +L  D    +D
Sbjct: 1217 CPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFRVCGKLSSDVCPTSD 1274


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 17/83 (20%)

Query: 3   LPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAM-------------GEKTG 49
           +PQ  L ++    +   A  VVVG ++ +   DRV  ++  +             GE   
Sbjct: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222

Query: 50  MTRNPHFSHDNWIPT----FFST 68
            TR+P F+H+N + T    FFST
Sbjct: 223 QTRSPEFTHENPLETRNICFFST 245


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 27.7 bits (60), Expect = 4.5
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 17/83 (20%)

Query: 3   LPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAM-------------GEKTG 49
           +PQ  L ++    +   A  VVVG ++ I   DRV  ++  +             GE   
Sbjct: 155 VPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEP 214

Query: 50  MTRNPHFSHDNWIP----TFFST 68
            TR+P  +HDN +     TFFST
Sbjct: 215 QTRSPDCTHDNPLETRNITFFST 237


>gi|30425382 signal-regulatory protein delta [Homo sapiens]
          Length = 197

 Score = 27.3 bits (59), Expect = 5.8
 Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)

Query: 93  PNCPVVRLSGQRCN---IWEFMQGNRPLVLNFGSCTUP 127
           PN PV+   G   N   I+ F QGN P V   G  T P
Sbjct: 58  PNGPVLWFKGTGPNRKLIYNFKQGNFPRVKEIGDTTKP 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.143    0.475 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,226,833
Number of Sequences: 37866
Number of extensions: 237774
Number of successful extensions: 439
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 430
Number of HSP's gapped (non-prelim): 13
length of query: 161
length of database: 18,247,518
effective HSP length: 94
effective length of query: 67
effective length of database: 14,688,114
effective search space: 984103638
effective search space used: 984103638
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.