Guide to the Human Genome
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Name: DIO2 Sequence: fasta or formatted (273aa) NCBI GI: 7549803
Description:

deiodinase, iodothyronine, type II isoform a

Referenced in:

Selenium Proteins
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [309aa] deiodinase, iodothyronine, type II isoform b
alt mRNA [273aa] deiodinase, iodothyronine, type II isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         20           3
 C cysteine            2.2          6           1
 D aspartate           4.8         13           1
 E glutamate           5.9         16           2
 F phenylalanine       5.5         15           2
 G glycine             6.2         17           2
 H histidine           2.2          6           1
 I isoleucine          3.7         10           1
 K lysine              5.5         15           2
 L leucine            12.1         33           3
 M methionine          1.1          3           1
 N asparagine          4.0         11           2
 P proline             4.4         12           2
 Q glutamine           4.4         12           2
 R arginine            5.9         16           2
 S serine              9.2         25           2
 T threonine           3.3          9           1
 U selenocysteine      0.7          2           1
 V valine              8.1         22           2
 W tryptophan          1.5          4           1
 Y tyrosine            2.2          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   deiodinase, iodothyronine, type II isoform a 
DIO2                  1.000   deiodinase, iodothyronine, type II isoform a 
DIO2                  0.965   deiodinase, iodothyronine, type II isoform b 
DIO3                  0.245   deiodinase, iodothyronine, type III 
DIO1                  0.222   deiodinase, iodothyronine, type I isoform a 
DIO1                  0.204   deiodinase, iodothyronine, type I isoform b 
DIO1                  0.091   deiodinase, iodothyronine, type I isoform d 
DIO1                  0.091   deiodinase, iodothyronine, type I isoform c 
LOC100129238          0.013   PREDICTED: hypothetical protein 
LOC100129238          0.013   PREDICTED: hypothetical protein 
LRRC49                0.013   leucine rich repeat containing 49 
DDX60L                0.012   DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom...
SPIRE2                0.010   spire homolog 2 
PARD3                 0.008   partitioning-defective protein 3 homolog 
TSR1                  0.008   TSR1, 20S rRNA accumulation 
XYLB                  0.006   xylulokinase 
C10orf54              0.006   platelet receptor Gi24 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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