Guide to the Human Genome
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Search of human proteins with 89257346

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89257346 G protein-coupled receptor 20 [Homo sapiens]
         (358 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89257346 G protein-coupled receptor 20 [Homo sapiens]              726   0.0  
gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens]          125   6e-29
gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens]            125   6e-29
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]            122   4e-28
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre...   121   8e-28
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa...   121   1e-27
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa...   121   1e-27
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap...   121   1e-27
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap...   120   1e-27
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]                117   2e-26
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]   116   3e-26
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]   116   3e-26
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]     116   3e-26
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]   116   3e-26
gi|28872720 purinergic receptor P2Y2 [Homo sapiens]                   115   8e-26
gi|28872745 purinergic receptor P2Y2 [Homo sapiens]                   115   8e-26
gi|28872743 purinergic receptor P2Y2 [Homo sapiens]                   115   8e-26
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]    114   2e-25
gi|33695097 G protein-coupled receptor 35 [Homo sapiens]              113   2e-25
gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]            113   3e-25
gi|166362740 coagulation factor II receptor precursor [Homo sapi...   112   4e-25
gi|39725940 opioid receptor, kappa 1 [Homo sapiens]                   111   9e-25
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   110   1e-24
gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]          110   3e-24
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]      108   1e-23
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]       108   1e-23
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]     108   1e-23
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]     108   1e-23
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]     108   1e-23
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]     108   1e-23

>gi|89257346 G protein-coupled receptor 20 [Homo sapiens]
          Length = 358

 Score =  726 bits (1874), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MPSVSPAGPSAGAVPNATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAVH 60
           MPSVSPAGPSAGAVPNATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAVH
Sbjct: 1   MPSVSPAGPSAGAVPNATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAVH 60

Query: 61  GAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGARGCL 120
           GAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGARGCL
Sbjct: 61  GAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGARGCL 120

Query: 121 RCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAGA 180
           RCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAGA
Sbjct: 121 RCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAGA 180

Query: 181 VTLSVLGVTGSRPCCRVFALTVLEFLLPLLVISVFTGRIMCALSRPGLLHQGRQRRVRAM 240
           VTLSVLGVTGSRPCCRVFALTVLEFLLPLLVISVFTGRIMCALSRPGLLHQGRQRRVRAM
Sbjct: 181 VTLSVLGVTGSRPCCRVFALTVLEFLLPLLVISVFTGRIMCALSRPGLLHQGRQRRVRAM 240

Query: 241 QLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFV 300
           QLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFV
Sbjct: 241 QLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFV 300

Query: 301 TSGFQATVRGLFGQHGEREPSSGDVVSMHRSSKGSGRHHILSAGPHALTQALANGPEA 358
           TSGFQATVRGLFGQHGEREPSSGDVVSMHRSSKGSGRHHILSAGPHALTQALANGPEA
Sbjct: 301 TSGFQATVRGLFGQHGEREPSSGDVVSMHRSSKGSGRHHILSAGPHALTQALANGPEA 358


>gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens]
          Length = 372

 Score =  125 bits (314), Expect = 6e-29
 Identities = 99/298 (33%), Positives = 137/298 (45%), Gaps = 41/298 (13%)

Query: 57  MAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTR---FAVY 113
           + V+  +  AGL LN LAL+VF    R  +   +Y  NL  +DLL  LSLP R   +A++
Sbjct: 26  LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALH 85

Query: 114 YGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAF 173
           +     L C     + + +NM+ S +FL  I VDRY AIV P   R  R+P  AR +C  
Sbjct: 86  HWPFPDLLCQTTGAI-FQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLG 144

Query: 174 VWLAAGAVTLSVLGVTGSRPC-CR-------------------------VFALTVLEFLL 207
           VW  A  +  +V      RP  CR                         V     L FLL
Sbjct: 145 VW--ALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLL 202

Query: 208 PLLVISVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALW 267
           PL  +   +GR+   L+RP       QRR + ++LLL  L+IFL+CF P+++      L 
Sbjct: 203 PLAAVVYSSGRVFWTLARPDATQS--QRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLL 260

Query: 268 PDMPHHTSLV-------VYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLFGQHGER 318
                  S+        V  V V L+  N  +DP+VY F   GF+ T+RGL   H  R
Sbjct: 261 RSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRAR 318


>gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens]
          Length = 372

 Score =  125 bits (314), Expect = 6e-29
 Identities = 99/298 (33%), Positives = 137/298 (45%), Gaps = 41/298 (13%)

Query: 57  MAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTR---FAVY 113
           + V+  +  AGL LN LAL+VF    R  +   +Y  NL  +DLL  LSLP R   +A++
Sbjct: 26  LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALH 85

Query: 114 YGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAF 173
           +     L C     + + +NM+ S +FL  I VDRY AIV P   R  R+P  AR +C  
Sbjct: 86  HWPFPDLLCQTTGAI-FQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLG 144

Query: 174 VWLAAGAVTLSVLGVTGSRPC-CR-------------------------VFALTVLEFLL 207
           VW  A  +  +V      RP  CR                         V     L FLL
Sbjct: 145 VW--ALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLL 202

Query: 208 PLLVISVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALW 267
           PL  +   +GR+   L+RP       QRR + ++LLL  L+IFL+CF P+++      L 
Sbjct: 203 PLAAVVYSSGRVFWTLARPDATQS--QRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLL 260

Query: 268 PDMPHHTSLV-------VYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLFGQHGER 318
                  S+        V  V V L+  N  +DP+VY F   GF+ T+RGL   H  R
Sbjct: 261 RSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRAR 318


>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
          Length = 370

 Score =  122 bits (307), Expect = 4e-28
 Identities = 79/279 (28%), Positives = 138/279 (49%), Gaps = 34/279 (12%)

Query: 58  AVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR 117
           AV+  +F+ GL+ N ++L+VFC R + ++ + I+  NL V+DLL   +LP  F ++Y   
Sbjct: 44  AVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLP--FKIFYNFN 101

Query: 118 -----GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCA 172
                G   C       +  N++ S+LFLTCI VDR+LAIV P  SR  R    +  VCA
Sbjct: 102 RHWPFGDTLCKISGT-AFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCA 160

Query: 173 FVWL--AAGAVTLSVLGVT----GSRPCCRVFA--------------LTVLEFLLPLLVI 212
            VW+   +G ++ S+   T     +  C   F+              + V+ F++PL++ 
Sbjct: 161 GVWILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILN 220

Query: 213 SVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMP- 271
              +  ++  L +P  L Q    + + ++++   + +F+VCF P+++     AL      
Sbjct: 221 VSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAI 280

Query: 272 -----HHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
                   + ++Y + + L++LN C DP +Y F    FQ
Sbjct: 281 TNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQ 319


>gi|34577052 coagulation factor II (thrombin) receptor-like 1
           precursor [Homo sapiens]
          Length = 397

 Score =  121 bits (304), Expect = 8e-28
 Identities = 92/276 (33%), Positives = 138/276 (50%), Gaps = 27/276 (9%)

Query: 56  LMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY-Y 114
           L  V+  +F+ GL  NG+AL+VF  RT+ K P+VIY  NL + DLL  +  P + A + +
Sbjct: 78  LPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIH 137

Query: 115 GARGCLRCAFPHVL-GYFL-NMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCA 172
           G       A  +VL G+F  NM+CSILF+TC+ V RY  IV P G  R ++   A  +  
Sbjct: 138 GNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSR-KKANIAIGISL 196

Query: 173 FVWLAAGAVT--LSVLGVTGSRPCCRV--------------------FALTVLEFLLPLL 210
            +WL    VT  L V+  T   P   +                     +L +  FL P  
Sbjct: 197 AIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAF 256

Query: 211 VISVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVA-VALWPD 269
           + +     ++  L    +     ++R RA++L++TVL ++L+CFTP +   V    L   
Sbjct: 257 LTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKS 316

Query: 270 MPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
                   +Y VA+ LS+LNSC+DP VY FV+  F+
Sbjct: 317 QGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFR 352


>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
           sapiens]
          Length = 344

 Score =  121 bits (303), Expect = 1e-27
 Identities = 83/279 (29%), Positives = 136/279 (48%), Gaps = 34/279 (12%)

Query: 63  IFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----G 118
           +F+ GL+ N +A+Y+F C  + +  +  Y INL ++DLL   +LP R   Y+  R    G
Sbjct: 27  VFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRI-FYFTTRNWPFG 85

Query: 119 CLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWL-- 176
            L C    +L ++ NM+ SILFLTCI VDR+LAIV P  S+  R    A+ VC  VWL  
Sbjct: 86  DLLCKISVML-FYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTV 144

Query: 177 ---AAGAVTLSVL---GVTGSRPCCR--------------VFALTVLEFLLPLLVISVFT 216
              +A AV +      G   S  C                V  + ++ F +PL++    +
Sbjct: 145 IGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCS 204

Query: 217 GRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSL 276
             ++  L++P  L + +  + + ++++   LIIF  CF P++   +  +L          
Sbjct: 205 SMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNCS 264

Query: 277 VV------YHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
           VV      Y + + ++  N C DPIVY F +   Q +++
Sbjct: 265 VVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK 303


>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
           sapiens]
          Length = 344

 Score =  121 bits (303), Expect = 1e-27
 Identities = 83/279 (29%), Positives = 136/279 (48%), Gaps = 34/279 (12%)

Query: 63  IFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----G 118
           +F+ GL+ N +A+Y+F C  + +  +  Y INL ++DLL   +LP R   Y+  R    G
Sbjct: 27  VFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRI-FYFTTRNWPFG 85

Query: 119 CLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWL-- 176
            L C    +L ++ NM+ SILFLTCI VDR+LAIV P  S+  R    A+ VC  VWL  
Sbjct: 86  DLLCKISVML-FYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTV 144

Query: 177 ---AAGAVTLSVL---GVTGSRPCCR--------------VFALTVLEFLLPLLVISVFT 216
              +A AV +      G   S  C                V  + ++ F +PL++    +
Sbjct: 145 IGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCS 204

Query: 217 GRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSL 276
             ++  L++P  L + +  + + ++++   LIIF  CF P++   +  +L          
Sbjct: 205 SMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNCS 264

Query: 277 VV------YHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
           VV      Y + + ++  N C DPIVY F +   Q +++
Sbjct: 265 VVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK 303


>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
           sapiens]
          Length = 344

 Score =  121 bits (303), Expect = 1e-27
 Identities = 83/279 (29%), Positives = 136/279 (48%), Gaps = 34/279 (12%)

Query: 63  IFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----G 118
           +F+ GL+ N +A+Y+F C  + +  +  Y INL ++DLL   +LP R   Y+  R    G
Sbjct: 27  VFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRI-FYFTTRNWPFG 85

Query: 119 CLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWL-- 176
            L C    +L ++ NM+ SILFLTCI VDR+LAIV P  S+  R    A+ VC  VWL  
Sbjct: 86  DLLCKISVML-FYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTV 144

Query: 177 ---AAGAVTLSVL---GVTGSRPCCR--------------VFALTVLEFLLPLLVISVFT 216
              +A AV +      G   S  C                V  + ++ F +PL++    +
Sbjct: 145 IGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCS 204

Query: 217 GRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSL 276
             ++  L++P  L + +  + + ++++   LIIF  CF P++   +  +L          
Sbjct: 205 SMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNCS 264

Query: 277 VV------YHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
           VV      Y + + ++  N C DPIVY F +   Q +++
Sbjct: 265 VVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIK 303


>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
           sapiens]
          Length = 359

 Score =  120 bits (302), Expect = 1e-27
 Identities = 98/300 (32%), Positives = 145/300 (48%), Gaps = 46/300 (15%)

Query: 50  PGLWLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTR 109
           P + +AL  V+  +    +  N  +L+V C R   ++PSVI+ INL VTDL++   LP  
Sbjct: 20  PAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLP-- 77

Query: 110 FAVYYGAR------GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQ 163
           F +YY         G L C    V  ++ NM+ SIL +TCI V+R+L ++ P  S+R R+
Sbjct: 78  FQIYYHCNRHHWVFGVLLCNVVTV-AFYANMYSSILTMTCISVERFLGVLYPLSSKRWRR 136

Query: 164 PACARAVCAFVWLAAGAVTLSVLGVT---------GSRPCCRV----------------F 198
              A A CA  WL      LS L  T         G   C  V                F
Sbjct: 137 RRYAVAACAGTWLLL-LTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLF 195

Query: 199 ALTVLEFLLPLLV-ISVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPF 257
            + +L FL+P ++ ++ +T  I+  L R    H GR++R RA+ L   VL+ F+ CF P 
Sbjct: 196 TIFILLFLIPFVITVACYTATIL-KLLRTEEAH-GREQRRRAVGLAAVVLLAFVTCFAPN 253

Query: 258 H----ARQVAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLFG 313
           +    A  V+   +    +H    VY + + LS LN+C+DP VY F +  FQ  +R   G
Sbjct: 254 NFVLLAHIVSRLFYGKSYYH----VYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLG 309


>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
          Length = 365

 Score =  117 bits (292), Expect = 2e-26
 Identities = 92/290 (31%), Positives = 133/290 (45%), Gaps = 31/290 (10%)

Query: 53  WLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAV 112
           ++ L   +  +F+ GL LN   L++F  R R    +  Y  +L ++D L  LSLPT    
Sbjct: 35  FILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPT-LIY 93

Query: 113 YYGAR-----GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACA 167
           YY A      G   C F   L Y+ N++CS+LFLTCI V RYL I  P  + R  +P  A
Sbjct: 94  YYAAHNHWPFGTEICKFVRFLFYW-NLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLA 152

Query: 168 RAVCAFVWL-AAGAVTLSVLGVTGSRPCCRVF------------------ALTVLEFLLP 208
             +C  VWL  AG +  ++  VT S     V                   A+  L F +P
Sbjct: 153 GLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVP 212

Query: 209 LLVISVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWP 268
            LV  V  G +   L +P         R+R+++ +  VL +F VCF PFH  +    L  
Sbjct: 213 CLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLAR 272

Query: 269 DMPHHTSL-----VVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLFG 313
            +     +     VVY V   L+S NSC+DP++Y      ++  +R L G
Sbjct: 273 LLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCG 322


>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
          Length = 339

 Score =  116 bits (291), Expect = 3e-26
 Identities = 85/271 (31%), Positives = 132/271 (48%), Gaps = 36/271 (13%)

Query: 64  FLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----GC 119
           F+  LV N LAL++F    ++ TP+ ++ ++L V DL   L LPTR   ++       G 
Sbjct: 42  FILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGE 101

Query: 120 LRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAG 179
           + C     L ++LNM+ SI FLTCI  DR+LAIV P  S + R+P  A   CAF+W+   
Sbjct: 102 IACRLTGFL-FYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV- 159

Query: 180 AVTLSVLGVTGSR-------PCCRVFALTVLEFLLPLLVISV---FTGRIMCALSRPGLL 229
           AV ++ L V+           C +++        L  L ++    F   + C L     L
Sbjct: 160 AVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSL 219

Query: 230 HQG----RQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTS---------- 275
            QG    ++ + +A++++  VL IFLVCF P+H  +    L     H+ S          
Sbjct: 220 RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRSHGASCATQRI 274

Query: 276 -LVVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
             +   +   L+SLN  +DPI+Y FV   F+
Sbjct: 275 LALANRITSCLTSLNGALDPIMYFFVAEKFR 305


>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
          Length = 339

 Score =  116 bits (291), Expect = 3e-26
 Identities = 85/271 (31%), Positives = 132/271 (48%), Gaps = 36/271 (13%)

Query: 64  FLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----GC 119
           F+  LV N LAL++F    ++ TP+ ++ ++L V DL   L LPTR   ++       G 
Sbjct: 42  FILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGE 101

Query: 120 LRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAG 179
           + C     L ++LNM+ SI FLTCI  DR+LAIV P  S + R+P  A   CAF+W+   
Sbjct: 102 IACRLTGFL-FYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV- 159

Query: 180 AVTLSVLGVTGSR-------PCCRVFALTVLEFLLPLLVISV---FTGRIMCALSRPGLL 229
           AV ++ L V+           C +++        L  L ++    F   + C L     L
Sbjct: 160 AVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSL 219

Query: 230 HQG----RQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTS---------- 275
            QG    ++ + +A++++  VL IFLVCF P+H  +    L     H+ S          
Sbjct: 220 RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRSHGASCATQRI 274

Query: 276 -LVVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
             +   +   L+SLN  +DPI+Y FV   F+
Sbjct: 275 LALANRITSCLTSLNGALDPIMYFFVAEKFR 305


>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
          Length = 367

 Score =  116 bits (291), Expect = 3e-26
 Identities = 85/271 (31%), Positives = 132/271 (48%), Gaps = 36/271 (13%)

Query: 64  FLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----GC 119
           F+  LV N LAL++F    ++ TP+ ++ ++L V DL   L LPTR   ++       G 
Sbjct: 70  FILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGE 129

Query: 120 LRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAG 179
           + C     L ++LNM+ SI FLTCI  DR+LAIV P  S + R+P  A   CAF+W+   
Sbjct: 130 IACRLTGFL-FYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV- 187

Query: 180 AVTLSVLGVTGSR-------PCCRVFALTVLEFLLPLLVISV---FTGRIMCALSRPGLL 229
           AV ++ L V+           C +++        L  L ++    F   + C L     L
Sbjct: 188 AVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSL 247

Query: 230 HQG----RQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTS---------- 275
            QG    ++ + +A++++  VL IFLVCF P+H  +    L     H+ S          
Sbjct: 248 RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRSHGASCATQRI 302

Query: 276 -LVVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
             +   +   L+SLN  +DPI+Y FV   F+
Sbjct: 303 LALANRITSCLTSLNGALDPIMYFFVAEKFR 333


>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
          Length = 367

 Score =  116 bits (291), Expect = 3e-26
 Identities = 85/271 (31%), Positives = 132/271 (48%), Gaps = 36/271 (13%)

Query: 64  FLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----GC 119
           F+  LV N LAL++F    ++ TP+ ++ ++L V DL   L LPTR   ++       G 
Sbjct: 70  FILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGE 129

Query: 120 LRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAG 179
           + C     L ++LNM+ SI FLTCI  DR+LAIV P  S + R+P  A   CAF+W+   
Sbjct: 130 IACRLTGFL-FYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVV- 187

Query: 180 AVTLSVLGVTGSR-------PCCRVFALTVLEFLLPLLVISV---FTGRIMCALSRPGLL 229
           AV ++ L V+           C +++        L  L ++    F   + C L     L
Sbjct: 188 AVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSL 247

Query: 230 HQG----RQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTS---------- 275
            QG    ++ + +A++++  VL IFLVCF P+H  +    L     H+ S          
Sbjct: 248 RQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRSHGASCATQRI 302

Query: 276 -LVVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
             +   +   L+SLN  +DPI+Y FV   F+
Sbjct: 303 LALANRITSCLTSLNGALDPIMYFFVAEKFR 333


>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
          Length = 377

 Score =  115 bits (287), Expect = 8e-26
 Identities = 90/277 (32%), Positives = 129/277 (46%), Gaps = 35/277 (12%)

Query: 53  WLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAV 112
           ++ L   +G + + GL LN +ALY+F CR +    S  Y  +L V+D L   SLP    V
Sbjct: 33  YVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLP--LLV 90

Query: 113 YYGARG------CLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPAC 166
           YY ARG       + C     L ++ N++CSILFLTCI V R L ++RP  S R  +   
Sbjct: 91  YYYARGDHWPFSTVLCKLVRFL-FYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARY 149

Query: 167 ARAVCAFVWLAAGAVTLSVL-----GVTGSRPCC------RVFALTV--------LEFLL 207
           AR V   VW+   A    VL        G R  C       +F+  V        L F +
Sbjct: 150 ARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAV 209

Query: 208 PLLVISVFTGRIMCALSRPGLLHQGRQRRV--RAMQLLLTVLIIFLVCFTPFHARQVAVA 265
           P  VI V    +   L +P     G   R   ++++ +  VL +F +CF PFH  +    
Sbjct: 210 PFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYY 269

Query: 266 LWP--DMPHHTSLVV---YHVAVTLSSLNSCMDPIVY 297
            +   D+  HT   +   Y V   L+S NSC+DP++Y
Sbjct: 270 SFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306


>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
          Length = 377

 Score =  115 bits (287), Expect = 8e-26
 Identities = 90/277 (32%), Positives = 129/277 (46%), Gaps = 35/277 (12%)

Query: 53  WLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAV 112
           ++ L   +G + + GL LN +ALY+F CR +    S  Y  +L V+D L   SLP    V
Sbjct: 33  YVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLP--LLV 90

Query: 113 YYGARG------CLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPAC 166
           YY ARG       + C     L ++ N++CSILFLTCI V R L ++RP  S R  +   
Sbjct: 91  YYYARGDHWPFSTVLCKLVRFL-FYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARY 149

Query: 167 ARAVCAFVWLAAGAVTLSVL-----GVTGSRPCC------RVFALTV--------LEFLL 207
           AR V   VW+   A    VL        G R  C       +F+  V        L F +
Sbjct: 150 ARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAV 209

Query: 208 PLLVISVFTGRIMCALSRPGLLHQGRQRRV--RAMQLLLTVLIIFLVCFTPFHARQVAVA 265
           P  VI V    +   L +P     G   R   ++++ +  VL +F +CF PFH  +    
Sbjct: 210 PFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYY 269

Query: 266 LWP--DMPHHTSLVV---YHVAVTLSSLNSCMDPIVY 297
            +   D+  HT   +   Y V   L+S NSC+DP++Y
Sbjct: 270 SFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306


>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
          Length = 377

 Score =  115 bits (287), Expect = 8e-26
 Identities = 90/277 (32%), Positives = 129/277 (46%), Gaps = 35/277 (12%)

Query: 53  WLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAV 112
           ++ L   +G + + GL LN +ALY+F CR +    S  Y  +L V+D L   SLP    V
Sbjct: 33  YVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLP--LLV 90

Query: 113 YYGARG------CLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPAC 166
           YY ARG       + C     L ++ N++CSILFLTCI V R L ++RP  S R  +   
Sbjct: 91  YYYARGDHWPFSTVLCKLVRFL-FYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARY 149

Query: 167 ARAVCAFVWLAAGAVTLSVL-----GVTGSRPCC------RVFALTV--------LEFLL 207
           AR V   VW+   A    VL        G R  C       +F+  V        L F +
Sbjct: 150 ARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAV 209

Query: 208 PLLVISVFTGRIMCALSRPGLLHQGRQRRV--RAMQLLLTVLIIFLVCFTPFHARQVAVA 265
           P  VI V    +   L +P     G   R   ++++ +  VL +F +CF PFH  +    
Sbjct: 210 PFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYY 269

Query: 266 LWP--DMPHHTSLVV---YHVAVTLSSLNSCMDPIVY 297
            +   D+  HT   +   Y V   L+S NSC+DP++Y
Sbjct: 270 SFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306


>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
          Length = 361

 Score =  114 bits (284), Expect = 2e-25
 Identities = 74/283 (26%), Positives = 133/283 (46%), Gaps = 35/283 (12%)

Query: 60  HGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY---YGA 116
           +  +F+ GLV N LAL V     +    + +Y+ NLV++D+L   +LPTR A Y   +  
Sbjct: 38  YSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDW 97

Query: 117 R-GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVW 175
           R G   C     L +++N +  + F+TC+ +DR++A+V P    + ++   A+ VC FVW
Sbjct: 98  RIGDALCRIT-ALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVW 156

Query: 176 LAAGAVTLSVL-----GVTGSRPCCR--------------VFALTVLEFLLPLLVISVFT 216
           +   A TL +L          R  C               +     + ++LPL++I +  
Sbjct: 157 ILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICY 216

Query: 217 GRIMCALSRPGLLHQGRQR---RVRAMQLLLTVLIIFLVCFTPFHARQVAVAL------- 266
            +I C L R    +   ++     +A+  ++ ++++F++CFTP+H   +   +       
Sbjct: 217 SQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSN 276

Query: 267 -WPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATV 308
                  H+  +  H  V L + N CMDP +Y F   G++  V
Sbjct: 277 FLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKV 319


>gi|33695097 G protein-coupled receptor 35 [Homo sapiens]
          Length = 309

 Score =  113 bits (283), Expect = 2e-25
 Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 14/269 (5%)

Query: 50  PGLWLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTR 109
           P + L   A  G + + GL+LN LAL+VFCCR +  T + IY  NL V DL +  +LP  
Sbjct: 17  PAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFV 76

Query: 110 FAVYYGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARA 169
                       C     + Y  N + SI  +T I VDRY+A+  P  +R  R P  A A
Sbjct: 77  LHSLRDTSDTPLCQLSQGI-YLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAA 135

Query: 170 VCAFVW--LAAGAVTLSVLGVTGSRPCCR-------VFALTVLEFLLPLLVISVFTGRIM 220
           VCA +W  +    V   +LG+     C R         A  +L F LPL V+   + +++
Sbjct: 136 VCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVV 195

Query: 221 CALSRPGLLHQGRQRRVR-AMQLLLTVLIIFLVCFTPFHAR---QVAVALWPDMPHHTSL 276
            AL++      G+    R A +++   L++F+VCF P H     ++AV         T  
Sbjct: 196 TALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIR 255

Query: 277 VVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
              ++   LS  N C+D I Y ++   FQ
Sbjct: 256 RALYITSKLSDANCCLDAICYYYMAKEFQ 284


>gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]
          Length = 363

 Score =  113 bits (282), Expect = 3e-25
 Identities = 96/335 (28%), Positives = 152/335 (45%), Gaps = 43/335 (12%)

Query: 16  NATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAV---HGAIFLAGLVLNG 72
           N+T  TT +   SGL   L ++    +  L+ +       L A+   +  IF+ G ++N 
Sbjct: 4   NSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNI 63

Query: 73  LALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR-----GCLRCAFPHV 127
           + + +FCC+   K  S IY  NL V DLL+  +LP  +A YY  R     G + C    V
Sbjct: 64  VVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPL-WATYYSYRYDWLFGPVMC---KV 119

Query: 128 LGYF--LNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAGAVTL-- 183
            G F  LNM  SI F+TC+ VDRY +++ P  S+R R P  A  +   VW  A   +L  
Sbjct: 120 FGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQR-RNPWQASYIVPLVWCMACLSSLPT 178

Query: 184 ------SVLGVTGSRPCCRVF--------------ALTVLEFLLPLLVISVFTGRIMCAL 223
                   +   G   C   F                 +L F++PL+ I+     I   L
Sbjct: 179 FYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHL 238

Query: 224 SRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVAL-WPDMPHHTSLV----- 277
            +     + R  R + +++   V++ F++C+ PFH      AL W  + +   ++     
Sbjct: 239 LKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDL 298

Query: 278 VYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLF 312
               A+ L   NSC++P +YCFV + FQ  +R +F
Sbjct: 299 ALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF 333


>gi|166362740 coagulation factor II receptor precursor [Homo
           sapiens]
          Length = 425

 Score =  112 bits (281), Expect = 4e-25
 Identities = 95/340 (27%), Positives = 155/340 (45%), Gaps = 38/340 (11%)

Query: 16  NATAVTTVRTNASGLEVPLF-HLFARLDEELHGTFPGLWLALM--AVHGAIFLAGLVLNG 72
           N + +T  R  +     PL   L A + E+  G     WL L   +V+  +F+  L LN 
Sbjct: 62  NESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLNI 121

Query: 73  LALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGAR----GCLRCAFPHVL 128
           +A+ VF  + + K P+V+Y ++L   D+L    LP + + Y+       G   C F    
Sbjct: 122 MAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFV-TA 180

Query: 129 GYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVW--LAAGAVTLSVL 186
            ++ NM+ SIL +T I +DR+LA+V P  S   R    A   C  +W    AG V L + 
Sbjct: 181 AFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLK 240

Query: 187 GVTGSRP------CCRVFALTVLE--------------FLLPLLVISVFTGRIMCALSRP 226
             T   P      C  V   T+LE              F +PL++ +V    I+  LS  
Sbjct: 241 EQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSS 300

Query: 227 GLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPH----HTSLVVYHVA 282
            + +  R ++ RA+ L   V  IF++CF P +   + +A +  + H      +   Y + 
Sbjct: 301 AVAN--RSKKSRALFLSAAVFCIFIICFGPTNV--LLIAHYSFLSHTSTTEAAYFAYLLC 356

Query: 283 VTLSSLNSCMDPIVYCFVTSGFQATVRGLFGQHGEREPSS 322
           V +SS++ C+DP++Y + +S  Q  V  +       +PSS
Sbjct: 357 VCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSS 396


>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
          Length = 380

 Score =  111 bits (278), Expect = 9e-25
 Identities = 80/288 (27%), Positives = 136/288 (47%), Gaps = 29/288 (10%)

Query: 50  PGLWLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTR 109
           P + + + AV+  +F+ GLV N L ++V    T+ KT + IY  NL + D LV  ++P +
Sbjct: 56  PAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQ 115

Query: 110 FAVYYGAR---GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPAC 166
             VY       G + C     + Y+ NM  SI  LT + VDRY+A+  P  +   R P  
Sbjct: 116 STVYLMNSWPFGDVLCKIVISIDYY-NMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLK 174

Query: 167 ARAVCAFVWLAAGAVTLSVLGVTGSR--------PCCRVF--------------ALTVLE 204
           A+ +   +WL + +V +S + + G++         C   F               + +  
Sbjct: 175 AKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFA 234

Query: 205 FLLPLLVISVFTGRIMCALSRPGLLHQGRQRRV---RAMQLLLTVLIIFLVCFTPFHARQ 261
           F++P+L+I V    ++  L    LL   R++     R  +L+L V+ +F+VC+TP H   
Sbjct: 235 FVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFI 294

Query: 262 VAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
           +  AL        +L  Y+  + L   NS ++PI+Y F+   F+   R
Sbjct: 295 LVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFR 342


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  110 bits (276), Expect = 1e-24
 Identities = 86/279 (30%), Positives = 138/279 (49%), Gaps = 34/279 (12%)

Query: 54  LALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLP---TRF 110
           +A+  ++  + L GLV N L ++V     + KT + IY +NL V D L  LS+P   +  
Sbjct: 48  VAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSA 107

Query: 111 AVYYGARGCLRC-AFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARA 169
           A+ +   G + C A   V G  LNM  S+  LT + VDRY+A+V P  +   R+P+ A+ 
Sbjct: 108 ALRHWPFGSVLCRAVLSVDG--LNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKL 165

Query: 170 VCAFVWLAAGAVTLSVLGVTGSRP-------CCR------------VFALTVLEFLLPLL 210
           +   VWLA+  VTL +     +RP        C             V    +L FLLP+L
Sbjct: 166 INLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVL 225

Query: 211 VIS----VFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVAL 266
            I     +  G++     R G   Q R+   +  +L+L V+++F++C+ PF+  Q+    
Sbjct: 226 AIGLCYLLIVGKMRAVALRAG-WQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLF 284

Query: 267 WPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
              +       V HV++ LS  NSC +PI+Y F++  F+
Sbjct: 285 VTSL----DATVNHVSLILSYANSCANPILYGFLSDNFR 319


>gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]
          Length = 423

 Score =  110 bits (274), Expect = 3e-24
 Identities = 103/350 (29%), Positives = 153/350 (43%), Gaps = 52/350 (14%)

Query: 2   PSVSPAGPSAGAVPNATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAVHG 61
           PS SP+  SA      +A TTV  ++ G                H T   L  A +A   
Sbjct: 59  PSFSPSPSSA-----PSAFTTVGGSSGG--------------PCHPTSSSLVSAFLAPIL 99

Query: 62  AI-FLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY------- 113
           A+ F+ GLV N LAL++FC  TR  T + ++ ++LV  D L+  +LP R   Y       
Sbjct: 100 ALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWR 159

Query: 114 YGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAF 173
           +GA  C    F        N   S++FLT I ++RYL +V+P           A  V   
Sbjct: 160 FGAAACKVNLFM----LSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGG 215

Query: 174 VWLAAGAVTLSVLGVTGSRPCCRVF--------------ALTVLEFLLPLLVISVFTGRI 219
           +W+    +   +L  T S P C  +              AL +LEF LPL +I      I
Sbjct: 216 LWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSI 275

Query: 220 MCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVA--VALWPDMPHHTSLV 277
              +   GL   G+    RAM++L  V+ ++ +CF P     +A  VA W        L 
Sbjct: 276 GLTIRNRGL--GGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLC 333

Query: 278 --VYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLFG-QHGEREPSSGD 324
             ++H ++  + LNS +DP++YCF +  F    R L G   G + P S +
Sbjct: 334 TQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDE 383


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score =  108 bits (269), Expect = 1e-23
 Identities = 75/281 (26%), Positives = 131/281 (46%), Gaps = 26/281 (9%)

Query: 54  LALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY 113
           + +MA++  + + GL  N L +YV    T+ KT + IY  NL + D L   +LP +   Y
Sbjct: 164 ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNY 223

Query: 114 YGAR---GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAV 170
                  G + C     + Y+ NM  SI  L  + VDRY+A+  P  +   R P  A+ +
Sbjct: 224 LMGTWPFGTILCKIVISIDYY-NMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKII 282

Query: 171 CAFVWLAAGAVTLSVLGVT------GSRPCCRVFA-------------LTVLEFLLPLLV 211
               W+ + A+ L V+ +       GS  C   F+             + +  F++P+L+
Sbjct: 283 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 342

Query: 212 ISVFTGRIMCALSRPGLLHQGRQR---RVRAMQLLLTVLIIFLVCFTPFHARQVAVALWP 268
           I+V  G ++  L    +L   +++     R  +++L V+ +F+VC+TP H   +  AL  
Sbjct: 343 ITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT 402

Query: 269 DMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
                   V +H  + L   NSC++P++Y F+   F+   R
Sbjct: 403 IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFR 443


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score =  108 bits (269), Expect = 1e-23
 Identities = 75/281 (26%), Positives = 131/281 (46%), Gaps = 26/281 (9%)

Query: 54  LALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY 113
           + +MA++  + + GL  N L +YV    T+ KT + IY  NL + D L   +LP +   Y
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNY 130

Query: 114 YGAR---GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAV 170
                  G + C     + Y+ NM  SI  L  + VDRY+A+  P  +   R P  A+ +
Sbjct: 131 LMGTWPFGTILCKIVISIDYY-NMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKII 189

Query: 171 CAFVWLAAGAVTLSVLGVT------GSRPCCRVFA-------------LTVLEFLLPLLV 211
               W+ + A+ L V+ +       GS  C   F+             + +  F++P+L+
Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 249

Query: 212 ISVFTGRIMCALSRPGLLHQGRQR---RVRAMQLLLTVLIIFLVCFTPFHARQVAVALWP 268
           I+V  G ++  L    +L   +++     R  +++L V+ +F+VC+TP H   +  AL  
Sbjct: 250 ITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT 309

Query: 269 DMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
                   V +H  + L   NSC++P++Y F+   F+   R
Sbjct: 310 IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFR 350


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score =  108 bits (269), Expect = 1e-23
 Identities = 75/281 (26%), Positives = 131/281 (46%), Gaps = 26/281 (9%)

Query: 54  LALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY 113
           + +MA++  + + GL  N L +YV    T+ KT + IY  NL + D L   +LP +   Y
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNY 130

Query: 114 YGAR---GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAV 170
                  G + C     + Y+ NM  SI  L  + VDRY+A+  P  +   R P  A+ +
Sbjct: 131 LMGTWPFGTILCKIVISIDYY-NMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKII 189

Query: 171 CAFVWLAAGAVTLSVLGVT------GSRPCCRVFA-------------LTVLEFLLPLLV 211
               W+ + A+ L V+ +       GS  C   F+             + +  F++P+L+
Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 249

Query: 212 ISVFTGRIMCALSRPGLLHQGRQR---RVRAMQLLLTVLIIFLVCFTPFHARQVAVALWP 268
           I+V  G ++  L    +L   +++     R  +++L V+ +F+VC+TP H   +  AL  
Sbjct: 250 ITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT 309

Query: 269 DMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
                   V +H  + L   NSC++P++Y F+   F+   R
Sbjct: 310 IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFR 350


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score =  108 bits (269), Expect = 1e-23
 Identities = 75/281 (26%), Positives = 131/281 (46%), Gaps = 26/281 (9%)

Query: 54  LALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY 113
           + +MA++  + + GL  N L +YV    T+ KT + IY  NL + D L   +LP +   Y
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNY 130

Query: 114 YGAR---GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAV 170
                  G + C     + Y+ NM  SI  L  + VDRY+A+  P  +   R P  A+ +
Sbjct: 131 LMGTWPFGTILCKIVISIDYY-NMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKII 189

Query: 171 CAFVWLAAGAVTLSVLGVT------GSRPCCRVFA-------------LTVLEFLLPLLV 211
               W+ + A+ L V+ +       GS  C   F+             + +  F++P+L+
Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 249

Query: 212 ISVFTGRIMCALSRPGLLHQGRQR---RVRAMQLLLTVLIIFLVCFTPFHARQVAVALWP 268
           I+V  G ++  L    +L   +++     R  +++L V+ +F+VC+TP H   +  AL  
Sbjct: 250 ITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT 309

Query: 269 DMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
                   V +H  + L   NSC++P++Y F+   F+   R
Sbjct: 310 IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFR 350


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score =  108 bits (269), Expect = 1e-23
 Identities = 75/281 (26%), Positives = 131/281 (46%), Gaps = 26/281 (9%)

Query: 54  LALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY 113
           + +MA++  + + GL  N L +YV    T+ KT + IY  NL + D L   +LP +   Y
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNY 130

Query: 114 YGAR---GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAV 170
                  G + C     + Y+ NM  SI  L  + VDRY+A+  P  +   R P  A+ +
Sbjct: 131 LMGTWPFGTILCKIVISIDYY-NMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKII 189

Query: 171 CAFVWLAAGAVTLSVLGVT------GSRPCCRVFA-------------LTVLEFLLPLLV 211
               W+ + A+ L V+ +       GS  C   F+             + +  F++P+L+
Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 249

Query: 212 ISVFTGRIMCALSRPGLLHQGRQR---RVRAMQLLLTVLIIFLVCFTPFHARQVAVALWP 268
           I+V  G ++  L    +L   +++     R  +++L V+ +F+VC+TP H   +  AL  
Sbjct: 250 ITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT 309

Query: 269 DMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
                   V +H  + L   NSC++P++Y F+   F+   R
Sbjct: 310 IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFR 350


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score =  108 bits (269), Expect = 1e-23
 Identities = 75/281 (26%), Positives = 131/281 (46%), Gaps = 26/281 (9%)

Query: 54  LALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVY 113
           + +MA++  + + GL  N L +YV    T+ KT + IY  NL + D L   +LP +   Y
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNY 130

Query: 114 YGAR---GCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAV 170
                  G + C     + Y+ NM  SI  L  + VDRY+A+  P  +   R P  A+ +
Sbjct: 131 LMGTWPFGTILCKIVISIDYY-NMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKII 189

Query: 171 CAFVWLAAGAVTLSVLGVT------GSRPCCRVFA-------------LTVLEFLLPLLV 211
               W+ + A+ L V+ +       GS  C   F+             + +  F++P+L+
Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLI 249

Query: 212 ISVFTGRIMCALSRPGLLHQGRQR---RVRAMQLLLTVLIIFLVCFTPFHARQVAVALWP 268
           I+V  G ++  L    +L   +++     R  +++L V+ +F+VC+TP H   +  AL  
Sbjct: 250 ITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT 309

Query: 269 DMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVR 309
                   V +H  + L   NSC++P++Y F+   F+   R
Sbjct: 310 IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFR 350


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.141    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,856,989
Number of Sequences: 37866
Number of extensions: 599440
Number of successful extensions: 3027
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 207
Number of HSP's successfully gapped in prelim test: 236
Number of HSP's that attempted gapping in prelim test: 2133
Number of HSP's gapped (non-prelim): 571
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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