Search of human proteins with 89242141

Search of human proteins with 89242141

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89242141 colon cancer-associated protein Mic1 [Homo sapiens]
         (657 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89242141 colon cancer-associated protein Mic1 [Homo sapiens]      1318   0.0  
gi|37622899 ring finger protein 137 [Homo sapiens]                     36   0.098
gi|32567784 T-box 10 [Homo sapiens]                                    33   0.64 
gi|62241044 exocyst complex component 7 isoform 2 [Homo sapiens]       33   1.1  
gi|209862785 anoctamin 2 [Homo sapiens]                                32   2.4  
gi|73695475 protein BAP28 [Homo sapiens]                               32   2.4  
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           30   7.1  
gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]             30   7.1  
gi|126116565 MYC binding protein 2 [Homo sapiens]                      30   7.1  

>gi|89242141 colon cancer-associated protein Mic1 [Homo sapiens]
          Length = 657

 Score = 1318 bits (3411), Expect = 0.0
 Identities = 657/657 (100%), Positives = 657/657 (100%)

Query: 1   MGEEDYYLELCERPVQFEKANPVNCVFFDEANKQVFAVRSGGATGVVVKGPDDRNPISFR 60
           MGEEDYYLELCERPVQFEKANPVNCVFFDEANKQVFAVRSGGATGVVVKGPDDRNPISFR
Sbjct: 1   MGEEDYYLELCERPVQFEKANPVNCVFFDEANKQVFAVRSGGATGVVVKGPDDRNPISFR 60

Query: 61  MDDKGEVKCIKFSLENKILAVQRTSKTVDFCNFIPDNSQLEYTQECKTKNANILGFCWTS 120
           MDDKGEVKCIKFSLENKILAVQRTSKTVDFCNFIPDNSQLEYTQECKTKNANILGFCWTS
Sbjct: 61  MDDKGEVKCIKFSLENKILAVQRTSKTVDFCNFIPDNSQLEYTQECKTKNANILGFCWTS 120

Query: 121 STEIVFITDQGIEFYQVLPEKRSLKLLKSHNLNVNWYMYCPESAVILLSTTVLENVLQPF 180
           STEIVFITDQGIEFYQVLPEKRSLKLLKSHNLNVNWYMYCPESAVILLSTTVLENVLQPF
Sbjct: 121 STEIVFITDQGIEFYQVLPEKRSLKLLKSHNLNVNWYMYCPESAVILLSTTVLENVLQPF 180

Query: 181 HFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAE 240
           HFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAE
Sbjct: 181 HFRAGTMSKLPKFEIELPAAPKSTKPSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGAE 240

Query: 241 VVLYHLPREGACKKMHILKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSV 300
           VVLYHLPREGACKKMHILKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSV
Sbjct: 241 VVLYHLPREGACKKMHILKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIKLRGEFDGSV 300

Query: 301 TFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDIIISASQGYLWNLQ 360
           TFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDIIISASQGYLWNLQ
Sbjct: 301 TFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDIIISASQGYLWNLQ 360

Query: 361 VKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEY 420
           VKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEY
Sbjct: 361 VKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEY 420

Query: 421 KKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVI 480
           KKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVI
Sbjct: 421 KKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVI 480

Query: 481 AVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSL 540
           AVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSL
Sbjct: 481 AVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSL 540

Query: 541 ESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAA 600
           ESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAA
Sbjct: 541 ESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAA 600

Query: 601 KQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFKQIFGDQALMRPTTF 657
           KQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFKQIFGDQALMRPTTF
Sbjct: 601 KQTEDNMLFYTIFRFFEQRNQRLRGSPNFTPGEHCEEHVAFFKQIFGDQALMRPTTF 657


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 8/113 (7%)

Query: 384 KECKMVILSVCSQMLSESDRASLPV--IATVFDKLNHEYKKYLDAEQSYAMAVEAGQSRS 441
           KE  +++   CSQ       + +P+  +A  +    HE  ++L  EQ  A  +E G+ + 
Sbjct: 110 KEDVLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKR 169

Query: 442 SPLLKRPVRT--QAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSLNQ 492
           +   K  V T  Q+++ + + Y  +L    EKK+ PH+ + A +   + SL +
Sbjct: 170 TATWKIQVETRKQSIVWEFEKYQRLL----EKKQPPHRQLGAEVAAALASLQR 218


>gi|32567784 T-box 10 [Homo sapiens]
          Length = 385

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 45/204 (22%), Positives = 80/204 (39%), Gaps = 39/204 (19%)

Query: 310 RSIQPYQIPITGPAAVTSQS------PVPCKLY-----SSSWIV-------------FQP 345
           R   P+Q+ I G  ++   +      P+  K Y     SS+W+V             F P
Sbjct: 93  RMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHP 152

Query: 346 DIIISASQGYLWNLQV----KLEPIVNLLPDKGRLMDFLLQRKECKMVILSVC----SQM 397
           D   S ++G  W  Q+    KL+   NLL D G ++   + R + +  ++ V     S+ 
Sbjct: 153 D---SPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSER 209

Query: 398 LSESDRASLPVIATVFDKL----NHEYKKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQA 453
            ++ +  S     T F  +    NH   +   A   +A         S P+  RP+ +  
Sbjct: 210 YAQENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESDLDSWPVAPRPLLSVP 269

Query: 454 VLDQSDVYTHVLSAFVEKKEMPHK 477
               S +   VL    ++++ P+K
Sbjct: 270 ARSHSSLSPCVLKGATDREKDPNK 293


>gi|62241044 exocyst complex component 7 isoform 2 [Homo sapiens]
          Length = 653

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 11/98 (11%)

Query: 445 LKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYLHEL 504
           +KRP R   +  ++D Y H +SAFV+  +  ++ +  ++ E+      F   +Q  L  L
Sbjct: 266 VKRPGRDDMLDVETDAYIHCVSAFVKLAQSEYQLLADIIPEH-HQKKTFDSLIQDALDGL 324

Query: 505 VI----------KTLVQHNLFYMLHQFLQYHVLSDSKP 532
           ++          K +V+H+   +L  F     L  +KP
Sbjct: 325 MLEGENIVSAARKAIVRHDFSTVLTVFPILRHLKQTKP 362


>gi|209862785 anoctamin 2 [Homo sapiens]
          Length = 998

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 36/161 (22%)

Query: 357 WNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKL 416
           W+L   LEP   L P+    M+ ++Q     + +             AS P +A VF  L
Sbjct: 725 WDLDYSLEPYTGLTPE---YMEMIIQFGFVTLFV-------------ASFP-LAPVFALL 767

Query: 417 NHEYKKYLDAEQSYAMAVEAGQSRSSPLLKRP--VRTQAVLDQSDVYTHVLSAFVEKKEM 474
           N+  +  LDA++                L+RP  VRT+ +     ++  +LS   +   +
Sbjct: 768 NNVIEVRLDAKKFVTE------------LRRPDAVRTKDI----GIWFDILSGIGKFSVI 811

Query: 475 PHKFVIAVLMEYI-RSLNQFQIAVQHYLHELVIKTLVQHNL 514
            + FVIA+  ++I R + Q+  +    LH  V  TL   N+
Sbjct: 812 SNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNV 852


>gi|73695475 protein BAP28 [Homo sapiens]
          Length = 2144

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 24/114 (21%)

Query: 485 EYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFL-------QYHVLSDSKPLACLL 537
           +Y R+L+   + ++ +L E  I  L +  LF   HQF+       +Y  L+DS     L+
Sbjct: 435 KYPRTLD---VVLEEHLKE--IADLKKQELF---HQFVSLSTSGGKYQFLADSD--TSLM 484

Query: 538 LSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNI 591
           LSL     P   L+++ LK++   + E V+    K  VLA L       G DNI
Sbjct: 485 LSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARL-------GDDNI 531


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 33/173 (19%), Positives = 68/173 (39%), Gaps = 18/173 (10%)

Query: 358 NLQVKLEPIVNLLPDKGRLMD----FLLQRKECKMVILSVCSQMLSESDRASLPVIATVF 413
           +L+V+++  V  +  +  L+D    F    KE    +  +  +ML +    S+  +  + 
Sbjct: 621 HLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELI 680

Query: 414 DKLNHEYKKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKE 473
            +   +    LDA  +    ++ G+     L   P       +  D       + V   +
Sbjct: 681 KQFQQQQTATLDATLN---VIKEGEDLIQQLRSAPPSLGEPSEARD-------SAVSNNK 730

Query: 474 MPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHV 526
            PH   I+ +   ++ L+  Q+ ++   HE  IK     ++F  L  F QY +
Sbjct: 731 TPHSSSISHIESVLQQLDDAQVQMEELFHERKIKL----DIFLQLRIFEQYTI 779


>gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]
          Length = 1663

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 33/173 (19%), Positives = 68/173 (39%), Gaps = 18/173 (10%)

Query: 358 NLQVKLEPIVNLLPDKGRLMD----FLLQRKECKMVILSVCSQMLSESDRASLPVIATVF 413
           +L+V+++  V  +  +  L+D    F    KE    +  +  +ML +    S+  +  + 
Sbjct: 621 HLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELI 680

Query: 414 DKLNHEYKKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKE 473
            +   +    LDA  +    ++ G+     L   P       +  D       + V   +
Sbjct: 681 KQFQQQQTATLDATLN---VIKEGEDLIQQLRSAPPSLGEPSEARD-------SAVSNNK 730

Query: 474 MPHKFVIAVLMEYIRSLNQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHV 526
            PH   I+ +   ++ L+  Q+ ++   HE  IK     ++F  L  F QY +
Sbjct: 731 TPHSSSISHIESVLQQLDDAQVQMEELFHERKIKL----DIFLQLRIFEQYTI 779


>gi|126116565 MYC binding protein 2 [Homo sapiens]
          Length = 4640

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 51/268 (19%), Positives = 104/268 (38%), Gaps = 33/268 (12%)

Query: 279  HQDTETSVIFDIKLRGEFDGSVTFHHPVLPARSIQPYQIPITGPAAVTSQSPV--PC--- 333
            HQ  + + +F + L    + S+  +HP  P +S    Q+P +    ++   PV  PC   
Sbjct: 3303 HQVIKANALFLLSLSSAAEPSILCYHPAKPFQS----QLP-SVKEGISEDLPVKMPCLYL 3357

Query: 334  ----KLYSSSWIVFQPDIIISASQGYLWNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMV 389
                + +  +++ +Q D +      YL +  V   P +++ PD    + F       K +
Sbjct: 3358 QTLARHHHENFVGYQDDNLFQDEMRYLRSTSVP-APYISVTPDASPNV-FEEPESNMKSM 3415

Query: 390  ILSVCSQMLSESDRASLPVIATVFDKLNHEYKKYLDAEQSYAMAVEAGQSRS------SP 443
              S+ +  ++++D A   V    +  +  EY K      +   A+   +  S      S 
Sbjct: 3416 PPSLETSPITDTDLAKRTVFQRSYSVVASEYDKQHSILPARVKAIPRRRVNSGDTEVGSS 3475

Query: 444  LLKRPVRTQAVLDQSDVYTHVLSAF--VEKKEMPHKFVIAVLMEYIRSLNQFQIAVQHYL 501
            LL+ P         S   + ++SA   + K E   ++ +   +     L   +IA++  L
Sbjct: 3476 LLRHP---------SPELSRLISAHSSLSKGERNFQWPVLAFVIQHHDLEGLEIAMKQAL 3526

Query: 502  HELVIKTLVQHNLFYMLHQFLQYHVLSD 529
             +   +        ++L   +Q   L D
Sbjct: 3527 RKSACRVFAMEAFNWLLCNVIQTTSLHD 3554


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,513,220
Number of Sequences: 37866
Number of extensions: 978364
Number of successful extensions: 2248
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2244
Number of HSP's gapped (non-prelim): 12
length of query: 657
length of database: 18,247,518
effective HSP length: 109
effective length of query: 548
effective length of database: 14,120,124
effective search space: 7737827952
effective search space used: 7737827952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.