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Search of human proteins with 14150082
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14150082 mitochondrial carrier protein MGC4399 [Homo
sapiens]
(321 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 635 0.0
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 373 e-103
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 366 e-101
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 110 1e-24
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 109 4e-24
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 108 5e-24
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 105 7e-23
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 102 6e-22
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 102 6e-22
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 102 6e-22
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 102 6e-22
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 102 6e-22
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 102 6e-22
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 100 2e-21
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 100 2e-21
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 100 2e-21
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 100 3e-21
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 92 8e-19
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 91 1e-18
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 91 1e-18
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 89 4e-18
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 86 6e-17
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 82 6e-16
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 80 2e-15
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 80 2e-15
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 80 2e-15
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 80 2e-15
gi|157388925 solute carrier family 25, member 38 [Homo sapiens] 79 7e-15
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 77 2e-14
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 77 3e-14
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 635 bits (1639), Expect = 0.0
Identities = 321/321 (100%), Positives = 321/321 (100%)
Query: 1 MATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTIS 60
MATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTIS
Sbjct: 1 MATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTIS 60
Query: 61 GAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN 120
GAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN
Sbjct: 61 GAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN 120
Query: 121 GIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQT 180
GIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQT
Sbjct: 121 GIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQT 180
Query: 181 EGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAA 240
EGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAA
Sbjct: 181 EGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAA 240
Query: 241 ALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIP 300
ALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIP
Sbjct: 241 ALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIP 300
Query: 301 NTAIVLSTYELIVYLLEDRTQ 321
NTAIVLSTYELIVYLLEDRTQ
Sbjct: 301 NTAIVLSTYELIVYLLEDRTQ 321
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 373 bits (957), Expect = e-103
Identities = 188/312 (60%), Positives = 237/312 (75%), Gaps = 8/312 (2%)
Query: 8 KENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRP 67
+ +TL+HLFAGGCGGTVGAI TCPLEV+KTRLQSS + T+Y +V L T++GA + R
Sbjct: 3 QRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSV---TLYISEVQLNTMAGASVNRV 59
Query: 68 TSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNS 127
V+PG LK ILEKEGP+SLFRGLGPNLVGVAPSRA+YFA YS KE+ N +F P+S
Sbjct: 60 --VSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS 117
Query: 128 NIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFY 187
VH+ SA A F + NPIW++KTR+QL+ + RG ++M +C R VYQT+G++GFY
Sbjct: 118 TQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFY 177
Query: 188 RGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTE---KNSTSFFGLMAAAALSK 244
RG++ASYAGISET+I F IYES+K+ L E AS+ E K ++ F G+M AAA SK
Sbjct: 178 RGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSK 237
Query: 245 GCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAI 304
CA+ IAYPHEV+RTRLREEGTKY+SF QT L+ +EEGY + YRGL L+RQIPNTAI
Sbjct: 238 TCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAI 297
Query: 305 VLSTYELIVYLL 316
+++TYEL+VYLL
Sbjct: 298 MMATYELVVYLL 309
Score = 35.8 bits (81), Expect = 0.052
Identities = 27/107 (25%), Positives = 40/107 (37%), Gaps = 25/107 (23%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
+ A T P EV++TRL+ R+
Sbjct: 230 MLAAATSKTCATTIAYPHEVVRTRLREEGTKYRS-------------------------F 264
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNG 121
FQ L ++++EG SL+RGL +LV P+ A+ A Y NG
Sbjct: 265 FQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 311
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 366 bits (940), Expect = e-101
Identities = 187/312 (59%), Positives = 236/312 (75%), Gaps = 9/312 (2%)
Query: 8 KENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRP 67
+ +TL+HLFAGGCGGTVGAI TCPLEV+KTRLQSS + T+Y +V L T++GA + R
Sbjct: 3 QRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSV---TLYISEVQLNTMAGASVNRV 59
Query: 68 TSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNS 127
V+PG LK ILEKEGP+SLFRGLGPNLVGVAPSRA+YFA YS KE+ N +F P+S
Sbjct: 60 --VSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS 117
Query: 128 NIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFY 187
VH+ SA A F + NPIW++KTR+QL+ + RG ++M +C R VYQT+G++GFY
Sbjct: 118 TQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFY 177
Query: 188 RGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTE---KNSTSFFGLMAAAALSK 244
RG++ASYAGISET+I F IYES+K+ L E AS+ E K ++ F G+M AAA SK
Sbjct: 178 RGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSK 237
Query: 245 GCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAI 304
CA+ IAYPH V+RTRLREEGTKY+SF QT L+ +EEGY + YRGL L+RQIPNTAI
Sbjct: 238 TCATTIAYPH-VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAI 296
Query: 305 VLSTYELIVYLL 316
+++TYEL+VYLL
Sbjct: 297 MMATYELVVYLL 308
Score = 36.2 bits (82), Expect = 0.040
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 41 SSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVG 100
+S+ T+ YP V + G + FQ L ++++EG SL+RGL +LV
Sbjct: 235 TSKTCATTIAYPHVVRTRLREEG-----TKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVR 289
Query: 101 VAPSRAVYFACYSKAKEQFNG 121
P+ A+ A Y NG
Sbjct: 290 QIPNTAIMMATYELVVYLLNG 310
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 110 bits (276), Expect = 1e-24
Identities = 89/314 (28%), Positives = 137/314 (43%), Gaps = 38/314 (12%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQ-SSRLALRTVYYPQVHLGTISGAGMVRPTSVTP 72
+L AG GG + + PL+++K R S L LR Y
Sbjct: 25 NLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYN--------------------- 63
Query: 73 GLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKE-QFNGIFVPNSNIVH 131
G+ L +I + +G + L++G+ PN+ G S +YF Y+ K + G +
Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEY 123
Query: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKV------RGSKQMNTLQCARYVYQTEGIRG 185
+ SA A +T + NP+W+ KTR+ L+ R K M +Y+ EG+RG
Sbjct: 124 LVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGM--FDTLVKIYKYEGVRG 181
Query: 186 FYRGLTASYAGISETIICFAIYESLK-KYLKEAPLASSANGTEKNSTSFFGLMAAAALSK 244
Y+G G S + F YE LK KY + N + S ++ AALSK
Sbjct: 182 LYKGFVPGLFGTSHGALQFMAYELLKLKYNQHI------NRLPEAQLSTVEYISVAALSK 235
Query: 245 GCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAI 304
A YP++V+R RL+++ Y + +R+EG FY+G+ LIR P I
Sbjct: 236 IFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCI 295
Query: 305 VLSTYELIVYLLED 318
YE + + L D
Sbjct: 296 TFVVYENVSHFLLD 309
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 109 bits (272), Expect = 4e-24
Identities = 89/328 (27%), Positives = 144/328 (43%), Gaps = 37/328 (11%)
Query: 2 ATGGQQKEN------TLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVH 55
ATG + EN H+ AG G + P++ +KTR+QS
Sbjct: 30 ATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQS-------------- 75
Query: 56 LGTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKA 115
+S + TS+ + LK I+ EG RG+ ++G P+ A+YFACY
Sbjct: 76 ---LSPDPKAQYTSI----YGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENM 128
Query: 116 KEQFNGIF--VPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQC 173
K N +F NS++ + + A + +++MNP +VK R+Q+ S+ + + C
Sbjct: 129 KRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM----YNSQHRSAISC 184
Query: 174 ARYVYQTEGIRGFYRGLTASYA-GISETIICFAIYESLKKYLKEAPLASSANGTEKNSTS 232
R V++TEG+ FYR T I I F YE L++ + P + + S
Sbjct: 185 IRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVN--PHRTYNPQSHIISGG 242
Query: 233 FFGLMAAAALSK-GCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGL 291
G +AAAA + + E + L + R V++ G +++G+
Sbjct: 243 LAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGI 302
Query: 292 FAQLIRQIPNTAIVLSTYELIVYLLEDR 319
A++I Q+P+TAI S YE Y L R
Sbjct: 303 QARVIYQMPSTAISWSVYEFFKYFLTKR 330
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 108 bits (271), Expect = 5e-24
Identities = 86/304 (28%), Positives = 136/304 (44%), Gaps = 44/304 (14%)
Query: 18 GGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQV 77
G G VGA P++++KTR+Q+ R G+G V + F
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQR-----------------GSGSVVGELMYKNSFDC 375
Query: 78 LKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN----GIFVPNSNIVHIF 133
K +L EG L+RGL P L+GVAP +A+ +++F + +P +
Sbjct: 376 FKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGC 435
Query: 134 SAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTAS 193
+ GS TN P+ +VK R+Q+ ++ +++ L R + GI G Y+G A
Sbjct: 436 AGGSQVIFTN----PLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKAC 487
Query: 194 YA-GISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAY 252
+ I + I F +Y K L + E L+AA A++ A+ +
Sbjct: 488 FLRDIPFSAIYFPVYAHCKLLLAD----------ENGHVGGLNLLAAGAMAGVPAASLVT 537
Query: 253 PHEVIRTRL----REEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLST 308
P +VI+TRL R T Y + R + REEG AF++G A++ R P + L T
Sbjct: 538 PADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVT 597
Query: 309 YELI 312
YEL+
Sbjct: 598 YELL 601
Score = 56.6 bits (135), Expect = 3e-08
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 34/204 (16%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
+ AGGC G IFT PLE++K RLQ ++G +T G
Sbjct: 430 VLAGGCAGGSQVIFTNPLEIVKIRLQ------------------VAG-------EITTGP 464
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAK---EQFNGIFVPNSNIVH 131
++L G L++G + P A+YF Y+ K NG + ++
Sbjct: 465 RVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENG----HVGGLN 520
Query: 132 IFSAGSAAFI-TNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
+ +AG+ A + SL+ P ++KTR+Q+ + + + C R + + EG F++G
Sbjct: 521 LLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGT 580
Query: 191 TAS-YAGISETIICFAIYESLKKY 213
A + + + YE L+++
Sbjct: 581 AARVFRSSPQFGVTLVTYELLQRW 604
Score = 52.4 bits (124), Expect = 5e-07
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 24/196 (12%)
Query: 133 FSAGSAA-FITNSLMNPIWMVKTRMQLEQKVRGS-----KQMNTLQCARYVYQTEGIRGF 186
F+ GS A + + + PI +VKTRMQ Q+ GS N+ C + V + EG G
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQ-NQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388
Query: 187 YRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGC 246
YRGL G++ AI ++ ++++ + +G+ + A L+ GC
Sbjct: 389 YRGLIPQLIGVAPEK---AIKLTVNDFVRDK--FTRRDGSVP--------LPAEVLAGGC 435
Query: 247 AS----CIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNT 302
A P E+++ RL+ G +A V R+ G Y+G A +R IP +
Sbjct: 436 AGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFS 495
Query: 303 AIVLSTYELIVYLLED 318
AI Y LL D
Sbjct: 496 AIYFPVYAHCKLLLAD 511
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 105 bits (261), Expect = 7e-23
Identities = 90/320 (28%), Positives = 137/320 (42%), Gaps = 48/320 (15%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
H+ AG G + P++ +KTR+QS + P +
Sbjct: 75 HMVAGAVAGILEHCVMYPIDCVKTRMQSLQ---------------------PDPAARYRN 113
Query: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVP--NSNIVH 131
+ + L I+ EG RGL G P+ A+YFACY K K+ + + P NS+I +
Sbjct: 114 VLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIAN 173
Query: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191
+ A + ++ MNP +VK RMQ+ S C R V+Q EG FYR T
Sbjct: 174 GAAGCVATLLHDAAMNPAEVVKQRMQMYN----SPYHRVTDCVRAVWQNEGAGAFYRSYT 229
Query: 192 ASYA-GISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCI 250
+ I F YE L+++ P + S + G +AAAA +
Sbjct: 230 TQLTMNVPFQAIHFMTYEFLQEHFN--PQRRYNPSSHVLSGACAGAVAAAATT------- 280
Query: 251 AYPHEVIRTRLR-EEGTKYKSFV--------QTARLVFREEGYLAFYRGLFAQLIRQIPN 301
P +V +T L +E S + R V++ G A++RG+ A++I QIP+
Sbjct: 281 --PLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPS 338
Query: 302 TAIVLSTYELIVYLLEDRTQ 321
TAI S YE YL+ R +
Sbjct: 339 TAIAWSVYEFFKYLITKRQE 358
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 18/108 (16%)
Query: 6 QQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSR-LALRTVYYPQVHLGTISGAGM 64
Q++ N H+ +G C G V A T PL+V KT L + LAL + H+
Sbjct: 256 QRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNS------HI-------- 301
Query: 65 VRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACY 112
T G+ +++ + G + FRG+ ++ PS A+ ++ Y
Sbjct: 302 ---TGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVY 346
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 102 bits (253), Expect = 6e-22
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 229
Query: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 230 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 284
Query: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 285 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 341
Query: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 342 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 395
Query: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
Query: 308 TYE 310
YE
Sbjct: 456 VYE 458
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
G +E +H L AG G + P+EV+KTR+
Sbjct: 272 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 309
Query: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 310 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 367
Query: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 368 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 427
Query: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 428 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 62.4 bits (150), Expect = 5e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
Query: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 247 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 296
Query: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 297 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
Query: 308 TYELI 312
YE +
Sbjct: 356 VYETL 360
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 102 bits (253), Expect = 6e-22
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 263
Query: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 264 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 318
Query: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 319 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 375
Query: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 376 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 429
Query: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 430 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
Query: 308 TYE 310
YE
Sbjct: 490 VYE 492
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
G +E +H L AG G + P+EV+KTR+
Sbjct: 306 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 343
Query: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 344 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 401
Query: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 402 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 461
Query: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 462 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 62.4 bits (150), Expect = 5e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 280
Query: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 281 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 330
Query: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 331 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 389
Query: 308 TYELI 312
YE +
Sbjct: 390 VYETL 394
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 102 bits (253), Expect = 6e-22
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 209 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 249
Query: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 250 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 304
Query: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 305 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 361
Query: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 362 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 415
Query: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 416 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 475
Query: 308 TYE 310
YE
Sbjct: 476 VYE 478
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
G +E +H L AG G + P+EV+KTR+
Sbjct: 292 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 329
Query: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 330 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 387
Query: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 388 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 447
Query: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 448 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 62.4 bits (150), Expect = 5e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 209 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 266
Query: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 267 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 316
Query: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 317 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 375
Query: 308 TYELI 312
YE +
Sbjct: 376 VYETL 380
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 102 bits (253), Expect = 6e-22
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 229
Query: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 230 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 284
Query: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 285 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 341
Query: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 342 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 395
Query: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
Query: 308 TYE 310
YE
Sbjct: 456 VYE 458
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
G +E +H L AG G + P+EV+KTR+
Sbjct: 272 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 309
Query: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 310 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 367
Query: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 368 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 427
Query: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 428 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 62.4 bits (150), Expect = 5e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
Query: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 247 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 296
Query: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 297 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
Query: 308 TYELI 312
YE +
Sbjct: 356 VYETL 360
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 102 bits (253), Expect = 6e-22
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 86 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 126
Query: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 127 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 181
Query: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 182 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 238
Query: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 239 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 292
Query: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 293 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 352
Query: 308 TYE 310
YE
Sbjct: 353 VYE 355
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
G +E +H L AG G + P+EV+KTR+
Sbjct: 169 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 206
Query: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 207 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 264
Query: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 265 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 324
Query: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 325 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 62.4 bits (150), Expect = 5e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 86 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 143
Query: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 144 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 193
Query: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 194 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 252
Query: 308 TYELI 312
YE +
Sbjct: 253 VYETL 257
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 102 bits (253), Expect = 6e-22
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 263
Query: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 264 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 318
Query: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 319 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 375
Query: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 376 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 429
Query: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 430 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
Query: 308 TYE 310
YE
Sbjct: 490 VYE 492
Score = 79.0 bits (193), Expect = 5e-15
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
G +E +H L AG G + P+EV+KTR+
Sbjct: 306 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 343
Query: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 344 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 401
Query: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 402 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 461
Query: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 462 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 62.4 bits (150), Expect = 5e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 280
Query: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 281 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 330
Query: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 331 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 389
Query: 308 TYELI 312
YE +
Sbjct: 390 VYETL 394
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 100 bits (249), Expect = 2e-21
Identities = 79/307 (25%), Positives = 136/307 (44%), Gaps = 37/307 (12%)
Query: 8 KENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRP 67
KE L +G G V T PL+ K +Q VY + + + G
Sbjct: 89 KEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQ--------VYSSKTNFTNLLGG----- 135
Query: 68 TSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNS 127
L+S++++ G +SL+RG G N++ +AP A+ F+ + + K F GI
Sbjct: 136 ----------LQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPP 185
Query: 128 NIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFY 187
+ + A I+ +L+NP+ ++KTR+ L R + L CAR + Q EG R Y
Sbjct: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLR---RTGQYKGLLDCARQILQREGTRALY 242
Query: 188 RGLTASYAG-ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGC 246
RG + G I A+YE L+ + + +G + S +++ LS C
Sbjct: 243 RGYLPNMLGIIPYACTDLAVYEMLQCFWVK-------SGRDMGDPSGLVSLSSVTLSTTC 295
Query: 247 ASCIAYPHEVIRTRLREEGT---KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTA 303
+YP ++RTR++ + T + + + ++G+L YRG+ L++ +P
Sbjct: 296 GQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGG 355
Query: 304 IVLSTYE 310
I YE
Sbjct: 356 ISYVVYE 362
Score = 63.5 bits (153), Expect = 2e-10
Identities = 55/208 (26%), Positives = 86/208 (41%), Gaps = 37/208 (17%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
L AG + P+EV+KTRL +R T GL
Sbjct: 190 LLAGSLAVAISQTLINPMEVLKTRLT------------------------LRRTGQYKGL 225
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPN-------S 127
+ IL++EG ++L+RG PN++G+ P A Y E +V + S
Sbjct: 226 LDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVY----EMLQCFWVKSGRDMGDPS 281
Query: 128 NIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFY 187
+V + S + P+ +V+TRMQ + V GS R + Q +G G Y
Sbjct: 282 GLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQ-QGWLGLY 340
Query: 188 RGLTASYAGISET-IICFAIYESLKKYL 214
RG+T + + I + +YE++KK L
Sbjct: 341 RGMTPTLLKVLPAGGISYVVYEAMKKTL 368
Score = 52.8 bits (125), Expect = 4e-07
Identities = 47/184 (25%), Positives = 79/184 (42%), Gaps = 16/184 (8%)
Query: 132 IFSAGSAAFITNSLMNPIWMVKTRMQL-EQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
+ S A ++ + P+ K MQ+ K + + LQ + Q G R +RG
Sbjct: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQS---MVQEGGFRSLWRGN 152
Query: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ I+ E I F+++E K Y + S F + A +L+ +
Sbjct: 153 GINVLKIAPEYAIKFSVFEQCKNYFCGI----------QGSPPFQERLLAGSLAVAISQT 202
Query: 250 IAYPHEVIRTRLREEGT-KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLST 308
+ P EV++TRL T +YK + AR + + EG A YRG ++ IP L+
Sbjct: 203 LINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAV 262
Query: 309 YELI 312
YE++
Sbjct: 263 YEML 266
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 100 bits (248), Expect = 2e-21
Identities = 86/300 (28%), Positives = 133/300 (44%), Gaps = 36/300 (12%)
Query: 18 GGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQV 77
G G VGA P++++KTR+Q+ R G+ G M + + F
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRST-----------GSFVGELMYKNS------FDC 377
Query: 78 LKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGS 137
K +L EG L+RGL P L+GVAP +A+ +++F I + G
Sbjct: 378 FKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGC 437
Query: 138 AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYA-G 196
A NP+ +VK R+Q+ ++ +++ L R + G G Y+G A +
Sbjct: 438 AGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRD 493
Query: 197 ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEV 256
I + I F Y +K AS AN E S L+ A A++ A+ + P +V
Sbjct: 494 IPFSAIYFPCYAHVK--------ASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADV 543
Query: 257 IRTRL----REEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELI 312
I+TRL R T Y + R + REEG A ++G A++ R P + L TYEL+
Sbjct: 544 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
Score = 61.2 bits (147), Expect = 1e-09
Identities = 51/203 (25%), Positives = 87/203 (42%), Gaps = 32/203 (15%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
+ AGGC G IFT PLE++K RLQ ++G +T G
Sbjct: 432 ILAGGCAGGSQVIFTNPLEIVKIRLQ------------------VAG-------EITTGP 466
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF---NGIFVPNSNIVH 131
S++ G +++G + P A+YF CY+ K F +G P S ++
Sbjct: 467 RVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLA 526
Query: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191
AG A SL+ P ++KTR+Q+ + + + C R + + EG + ++G
Sbjct: 527 GAIAGMPA---ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 583
Query: 192 AS-YAGISETIICFAIYESLKKY 213
A + + + YE L+++
Sbjct: 584 ARVFRSSPQFGVTLLTYELLQRW 606
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 21/105 (20%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
L AG G A P +VIKTRLQ + A +T Y G+
Sbjct: 524 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTY---------------------SGV 562
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119
+ IL +EGPK+L++G G + +P V Y + F
Sbjct: 563 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 607
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 100 bits (248), Expect = 2e-21
Identities = 86/300 (28%), Positives = 133/300 (44%), Gaps = 36/300 (12%)
Query: 18 GGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQV 77
G G VGA P++++KTR+Q+ R G+ G M + + F
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRST-----------GSFVGELMYKNS------FDC 378
Query: 78 LKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGS 137
K +L EG L+RGL P L+GVAP +A+ +++F I + G
Sbjct: 379 FKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGC 438
Query: 138 AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYA-G 196
A NP+ +VK R+Q+ ++ +++ L R + G G Y+G A +
Sbjct: 439 AGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRD 494
Query: 197 ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEV 256
I + I F Y +K AS AN E S L+ A A++ A+ + P +V
Sbjct: 495 IPFSAIYFPCYAHVK--------ASFAN--EDGQVSPGSLLLAGAIAGMPAASLVTPADV 544
Query: 257 IRTRL----REEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELI 312
I+TRL R T Y + R + REEG A ++G A++ R P + L TYEL+
Sbjct: 545 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604
Score = 61.2 bits (147), Expect = 1e-09
Identities = 51/203 (25%), Positives = 87/203 (42%), Gaps = 32/203 (15%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
+ AGGC G IFT PLE++K RLQ ++G +T G
Sbjct: 433 ILAGGCAGGSQVIFTNPLEIVKIRLQ------------------VAG-------EITTGP 467
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF---NGIFVPNSNIVH 131
S++ G +++G + P A+YF CY+ K F +G P S ++
Sbjct: 468 RVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLA 527
Query: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191
AG A SL+ P ++KTR+Q+ + + + C R + + EG + ++G
Sbjct: 528 GAIAGMPA---ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 584
Query: 192 AS-YAGISETIICFAIYESLKKY 213
A + + + YE L+++
Sbjct: 585 ARVFRSSPQFGVTLLTYELLQRW 607
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 21/105 (20%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
L AG G A P +VIKTRLQ + A +T Y G+
Sbjct: 525 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTY---------------------SGV 563
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119
+ IL +EGPK+L++G G + +P V Y + F
Sbjct: 564 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 608
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 99.8 bits (247), Expect = 3e-21
Identities = 87/305 (28%), Positives = 135/305 (44%), Gaps = 45/305 (14%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
L AG G V T PL+ +K + QVH A ++ GL
Sbjct: 189 LVAGAVAGAVSRTGTAPLDRLKV-------------FMQVH------ASKTNRLNILGGL 229
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHI-- 132
+S++ + G +SL+RG G N++ +AP A+ F Y + K G +H+
Sbjct: 230 ----RSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILG----QQETLHVQE 281
Query: 133 -FSAGSAAFIT-NSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
F AGS A T +++ P+ ++KTR+ L R + L CAR + + EG R FYRG
Sbjct: 282 RFVAGSLAGATAQTIIYPMEVLKTRLTLR---RTGQYKGLLDCARRILEREGPRAFYRGY 338
Query: 191 TASYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ GI I A+YE+LK + + SA+ L+A +S C
Sbjct: 339 LPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSAD------PGILVLLACGTISSTCGQI 392
Query: 250 IAYPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIV 305
+YP ++RTR++ EG S + R + +EG YRG+ ++ IP +I
Sbjct: 393 ASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSIS 452
Query: 306 LSTYE 310
YE
Sbjct: 453 YVVYE 457
Score = 87.4 bits (215), Expect = 2e-17
Identities = 58/216 (26%), Positives = 102/216 (47%), Gaps = 30/216 (13%)
Query: 5 GQQKENTLLHLF-AGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAG 63
GQQ+ + F AG G P+EV+KTRL
Sbjct: 272 GQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRL------------------------ 307
Query: 64 MVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIF 123
+R T GL + ILE+EGP++ +RG PN++G+ P + A Y K + +
Sbjct: 308 TLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQY 367
Query: 124 VPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQ 179
+S I+ + + G+ + + + P+ +V+TRMQ + + G Q++ L R++
Sbjct: 368 SHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILS 427
Query: 180 TEGIRGFYRGLTASYAGISETI-ICFAIYESLKKYL 214
EG+RG YRG+ ++ + + I + +YE++K+ L
Sbjct: 428 QEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
Score = 59.7 bits (143), Expect = 3e-09
Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 14/162 (8%)
Query: 155 RMQLEQKVRGSK--QMNTLQCARYVYQTEGIRGFYRGLTASYAGIS-ETIICFAIYESLK 211
R+++ +V SK ++N L R + GIR +RG + I+ E+ I F YE +K
Sbjct: 208 RLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIK 267
Query: 212 KYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGT-KYKS 270
+ + ++ + A +L+ A I YP EV++TRL T +YK
Sbjct: 268 RAILG----------QQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKG 317
Query: 271 FVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELI 312
+ AR + EG AFYRG ++ IP I L+ YE +
Sbjct: 318 LLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 91.7 bits (226), Expect = 8e-19
Identities = 80/309 (25%), Positives = 132/309 (42%), Gaps = 29/309 (9%)
Query: 12 LLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVT 71
L +L AGG GG PL+ +K RLQ+ +L P ++ GT
Sbjct: 11 LKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPG--QPPMYSGT------------- 55
Query: 72 PGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVH 131
F + L +EG L+RG+ ++GV P AV F + K+ +
Sbjct: 56 ---FDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQ 112
Query: 132 IFSAGSAAFI-TNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
+F+AG + + T +M P +K +Q++ SK TL CA+ +YQ GIRG Y+G
Sbjct: 113 LFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGT 172
Query: 191 TAS-YAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
+ + + + F YE LK + G + S ++ A ++
Sbjct: 173 VLTLMRDVPASGMYFMTYEWLKNIF-------TPEGKRVSELSAPRILVAGGIAGIFNWA 225
Query: 250 IAYPHEVIRTRLR--EEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
+A P +V+++R + G F R + R+EG + Y+G A +IR P A
Sbjct: 226 VAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFL 285
Query: 308 TYELIVYLL 316
+E+ + L
Sbjct: 286 GFEVAMKFL 294
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 90.9 bits (224), Expect = 1e-18
Identities = 75/301 (24%), Positives = 124/301 (41%), Gaps = 37/301 (12%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
L AGG G V T PL+ +K +Q + G+ S +
Sbjct: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQ------------------VHGS-----KSDKMNI 234
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFS 134
F + ++++ G +SL+RG G N++ +AP AV F Y + K+ S
Sbjct: 235 FGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFIS 294
Query: 135 AGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASY 194
A + + P+ ++KTR+ + + + CA+ + + EG+ FY+G +
Sbjct: 295 GSMAGATAQTFIYPMEVMKTRLAVG---KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 351
Query: 195 AGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYP 253
GI I A+YE LK Y + S N L+ ALS C +YP
Sbjct: 352 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVN------PGVMVLLGCGALSSTCGQLASYP 405
Query: 254 HEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTY 309
++RTR++ EG+ + V R + +EG YRG+ ++ +P I Y
Sbjct: 406 LALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVY 465
Query: 310 E 310
E
Sbjct: 466 E 466
Score = 86.3 bits (212), Expect = 3e-17
Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 29/213 (13%)
Query: 7 QKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVR 66
QK T +G G F P+EV+KTRL V
Sbjct: 284 QKIGTFERFISGSMAGATAQTFIYPMEVMKTRLA------------------------VG 319
Query: 67 PTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPN 126
T G++ K IL+ EG + ++G PNL+G+ P + A Y K + F +
Sbjct: 320 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKD 379
Query: 127 S---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEG 182
S ++ + G+ + L + P+ +V+TRMQ + + GS Q+N + R + EG
Sbjct: 380 SVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEG 439
Query: 183 IRGFYRGLTASYAGISETI-ICFAIYESLKKYL 214
I G YRG+T ++ + + I + +YE++K+ L
Sbjct: 440 IPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472
Score = 66.6 bits (161), Expect = 3e-11
Identities = 55/185 (29%), Positives = 83/185 (44%), Gaps = 18/185 (9%)
Query: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSK--QMNTLQCARYVYQTEGIRGFYRG 189
+ + G A ++ + P+ +K MQ V GSK +MN R + + GIR +RG
Sbjct: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQ----VHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 253
Query: 190 LTASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCAS 248
+ I+ ET + F YE KK L E E F + +++ A
Sbjct: 254 NGTNVIKIAPETAVKFWAYEQYKKLLTE----------EGQKIGTFERFISGSMAGATAQ 303
Query: 249 CIAYPHEVIRTRLREEGT-KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TRL T +Y A+ + + EG AFY+G L+ IP I L+
Sbjct: 304 TFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLA 363
Query: 308 TYELI 312
YEL+
Sbjct: 364 VYELL 368
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 90.9 bits (224), Expect = 1e-18
Identities = 75/301 (24%), Positives = 124/301 (41%), Gaps = 37/301 (12%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
L AGG G V T PL+ +K +Q + G+ S +
Sbjct: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQ------------------VHGS-----KSDKMNI 215
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFS 134
F + ++++ G +SL+RG G N++ +AP AV F Y + K+ S
Sbjct: 216 FGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFIS 275
Query: 135 AGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASY 194
A + + P+ ++KTR+ + + + CA+ + + EG+ FY+G +
Sbjct: 276 GSMAGATAQTFIYPMEVMKTRLAVG---KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 332
Query: 195 AGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYP 253
GI I A+YE LK Y + S N L+ ALS C +YP
Sbjct: 333 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVN------PGVMVLLGCGALSSTCGQLASYP 386
Query: 254 HEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTY 309
++RTR++ EG+ + V R + +EG YRG+ ++ +P I Y
Sbjct: 387 LALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVY 446
Query: 310 E 310
E
Sbjct: 447 E 447
Score = 86.3 bits (212), Expect = 3e-17
Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 29/213 (13%)
Query: 7 QKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVR 66
QK T +G G F P+EV+KTRL V
Sbjct: 265 QKIGTFERFISGSMAGATAQTFIYPMEVMKTRLA------------------------VG 300
Query: 67 PTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPN 126
T G++ K IL+ EG + ++G PNL+G+ P + A Y K + F +
Sbjct: 301 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKD 360
Query: 127 S---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEG 182
S ++ + G+ + L + P+ +V+TRMQ + + GS Q+N + R + EG
Sbjct: 361 SVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEG 420
Query: 183 IRGFYRGLTASYAGISETI-ICFAIYESLKKYL 214
I G YRG+T ++ + + I + +YE++K+ L
Sbjct: 421 IPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 453
Score = 66.6 bits (161), Expect = 3e-11
Identities = 55/185 (29%), Positives = 83/185 (44%), Gaps = 18/185 (9%)
Query: 132 IFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSK--QMNTLQCARYVYQTEGIRGFYRG 189
+ + G A ++ + P+ +K MQ V GSK +MN R + + GIR +RG
Sbjct: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQ----VHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 234
Query: 190 LTASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCAS 248
+ I+ ET + F YE KK L E E F + +++ A
Sbjct: 235 NGTNVIKIAPETAVKFWAYEQYKKLLTE----------EGQKIGTFERFISGSMAGATAQ 284
Query: 249 CIAYPHEVIRTRLREEGT-KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
YP EV++TRL T +Y A+ + + EG AFY+G L+ IP I L+
Sbjct: 285 TFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLA 344
Query: 308 TYELI 312
YEL+
Sbjct: 345 VYELL 349
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 89.4 bits (220), Expect = 4e-18
Identities = 76/308 (24%), Positives = 133/308 (43%), Gaps = 44/308 (14%)
Query: 13 LHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTP 72
L AG GG G + P + +K RLQ +++V PQ
Sbjct: 3 LDFLAGCAGGVAGVLVGHPFDTVKVRLQ-----VQSVEKPQYR----------------- 40
Query: 73 GLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHI 132
G KSI+++E L++GLG L+G+ A+ F + + ++
Sbjct: 41 GTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALG-----HDSPLNQ 95
Query: 133 FSAGSAA-FITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191
F AG+AA I + P+ + KTR+QL+ +L C +Y EG+RG RG+
Sbjct: 96 FLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMV 155
Query: 192 ASYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCI 250
++ + + + F Y++L + L G E + A + G S +
Sbjct: 156 STLLRETPSFGVYFLTYDALTRAL----------GCEPGDRLLVPKLLLAGGTSGIVSWL 205
Query: 251 A-YPHEVIRTRLREEG----TKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIV 305
+ YP +V+++RL+ +G +Y+ + +R EG+ F RGL + L+R P A
Sbjct: 206 STYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAAT 265
Query: 306 LSTYELIV 313
+T +++
Sbjct: 266 FATVTVVL 273
Score = 59.7 bits (143), Expect = 3e-09
Identities = 48/190 (25%), Positives = 76/190 (40%), Gaps = 30/190 (15%)
Query: 9 ENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPT 68
++ L AG G + + CP+E+ KTRLQ + AG P
Sbjct: 90 DSPLNQFLAGAAAGAIQCVICCPMELAKTRLQ------------------LQDAG---PA 128
Query: 69 SVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAK-----EQFNGIF 123
G L I EG + + RG+ L+ PS VYF Y E + +
Sbjct: 129 RTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLL 188
Query: 124 VPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGI 183
VP + + G++ ++ P+ +VK+R+Q + + L C Y+ EG
Sbjct: 189 VPKL----LLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGW 244
Query: 184 RGFYRGLTAS 193
R F RGL ++
Sbjct: 245 RVFTRGLAST 254
Score = 54.7 bits (130), Expect = 1e-07
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 133 FSAGSAAFITNSLM-NPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191
F AG A + L+ +P VK R+Q+ Q V + TL C + + + E + G Y+GL
Sbjct: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQV-QSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63
Query: 192 ASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
+ G+ T I ++ L+ A G + F AA A+ C C
Sbjct: 64 SPLMGL--TFINALVFGVQGNTLR-------ALGHDSPLNQFLAGAAAGAIQ--CVICC- 111
Query: 252 YPHEVIRTRLREEGT----KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
P E+ +TRL+ + YK + ++ EG RG+ + L+R+ P+ +
Sbjct: 112 -PMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFL 170
Query: 308 TYELIVYLL 316
TY+ + L
Sbjct: 171 TYDALTRAL 179
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 85.5 bits (210), Expect = 6e-17
Identities = 80/314 (25%), Positives = 139/314 (44%), Gaps = 43/314 (13%)
Query: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
+ AGG G V PL+V+KTR Q R A Y L
Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKS--------------------L 56
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFS 134
+ I + EG ++G+ P ++ P RAV F + + K+ +V S +
Sbjct: 57 VDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLG--YVSLSPALTFAI 114
Query: 135 AGSAAFITNSLM-NPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEG--IRGFYRGLT 191
AG + +T +++ NP +VK +Q + ++Q +T+ AR + + EG ++G +GLT
Sbjct: 115 AGLGSGLTEAIVVNPFEVVKVGLQANRNTF-AEQPSTVGYARQIIKKEGWGLQGLNKGLT 173
Query: 192 ASYA--GISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
A+ G+ ++ F Y ++K + + F+ LS AS
Sbjct: 174 ATLGRHGVFN-MVYFGFYYNVKNMIPV---------NKDPILEFWRKFGIGLLSGTIASV 223
Query: 250 IAYPHEVIRTRLREEGT-----KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAI 304
I P +V ++R++ KY++ +T V++EEG LA Y+GL +++R P A+
Sbjct: 224 INIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAV 283
Query: 305 VLSTYELIVYLLED 318
+L YE L++
Sbjct: 284 MLLVYEYTYSWLQE 297
Score = 41.6 bits (96), Expect = 0.001
Identities = 53/210 (25%), Positives = 75/210 (35%), Gaps = 27/210 (12%)
Query: 12 LLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVT 71
L AG G AI P EV+K LQ++R +
Sbjct: 110 LTFAIAGLGSGLTEAIVVNPFEVVKVGLQANR----------------------NTFAEQ 147
Query: 72 PGLFQVLKSILEKE--GPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNI 129
P + I++KE G + L +GL L VYF Y K P
Sbjct: 148 PSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEF 207
Query: 130 VHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGS-KQMNTLQCARYVYQTEGIRGFY 187
F G + S++N P + K+R+Q Q V G K + VYQ EGI Y
Sbjct: 208 WRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALY 267
Query: 188 RGLTASYAGISE-TIICFAIYESLKKYLKE 216
+GL + + +YE +L+E
Sbjct: 268 KGLLPKIMRLGPGGAVMLLVYEYTYSWLQE 297
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 82.0 bits (201), Expect = 6e-16
Identities = 85/334 (25%), Positives = 144/334 (43%), Gaps = 42/334 (12%)
Query: 3 TGGQQ--KENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRT----VYYPQV-- 54
T GQ+ K L + A G + ++ PL+V+K RLQ+ L VY +
Sbjct: 5 TRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMD 64
Query: 55 HLGTISGAGMVRPTSVTPGLFQ----VLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFA 110
HL G + PG FQ I+ EG KSL+ GL P LV P+ +YF
Sbjct: 65 HLCVCEEGGN-KLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFT 123
Query: 111 CYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNT 170
CY + N + I + A F ++++P+ +++T+MQ SK+ +
Sbjct: 124 CYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQ-------SKKFSY 176
Query: 171 LQCARYV---YQTEGIRGFYRGLTAS-YAGISETIICFAIYESLKKYLKEAPLASSANGT 226
++ R+V +G +RG + + + + + YE LKK+L E +
Sbjct: 177 VELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEK--------S 228
Query: 227 EKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARL--------- 277
+F + ALS A+ P +V++T+ + + Y+S + L
Sbjct: 229 GLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMK 288
Query: 278 -VFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYE 310
+ + G+ + GL +LI+ P AI++STYE
Sbjct: 289 NIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYE 322
Score = 45.1 bits (105), Expect = 9e-05
Identities = 36/147 (24%), Positives = 71/147 (48%), Gaps = 17/147 (11%)
Query: 170 TLQCARYVYQTEGIRGFYRGLTASYA-GISETIICFAIYESLKKYLKEAPLASSANGTEK 228
TL + + EGI+ + GL + + T+I F Y+ L L+ +
Sbjct: 87 TLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSK--------LGE 138
Query: 229 NSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFR---EEGYL 285
N T + A +++ A + P E+IRT+++ +K S+V+ R V + E+G++
Sbjct: 139 NETCI--PIVAGIVARFGAVTVISPLELIRTKMQ---SKKFSYVELHRFVSKKVSEDGWI 193
Query: 286 AFYRGLFAQLIRQIPNTAIVLSTYELI 312
+ +RG ++R +P +A+ YE++
Sbjct: 194 SLWRGWAPTVLRDVPFSAMYWYNYEIL 220
Score = 44.3 bits (103), Expect = 1e-04
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 15/115 (13%)
Query: 5 GQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGM 64
G + +++ +G G+ A+ T P +V+KT+ Q+ L T +
Sbjct: 229 GLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQ-------------LWTYESHKI 275
Query: 65 VRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119
P ++ + ++K+I+ K G LF GL P L+ +AP+ A+ + Y K F
Sbjct: 276 SMPLHMSTWI--IMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFF 328
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 80.1 bits (196), Expect = 2e-15
Identities = 76/336 (22%), Positives = 139/336 (41%), Gaps = 50/336 (14%)
Query: 12 LLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA--------- 62
L + A G G V ++F PL+V+K RLQS R ++ + P L ++S
Sbjct: 12 LQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKWKCLLYCN 71
Query: 63 GMVRPTSVTP----------------GLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRA 106
G++ P + P G I+ EG ++L+ GL LV P+ A
Sbjct: 72 GVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATA 131
Query: 107 VYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSK 166
+YF Y + K G + + + + A T ++++P+ +++T++Q + +
Sbjct: 132 IYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHV--SYR 189
Query: 167 QMNTLQCARYVYQTEGIRGFYRGL-TASYAGISETIICFAIYESLKKYLKEAPLASSANG 225
++ C R G R + G + + + + + YE +K +L NG
Sbjct: 190 ELGA--CVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWL---------NG 238
Query: 226 -TEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTR----------LREEGTKYKSFVQT 274
K+ TS A +S A+ + P +V++T+ +R S
Sbjct: 239 FRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLL 298
Query: 275 ARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYE 310
R + E G + G ++I+ P+ AI++STYE
Sbjct: 299 LRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 15/103 (14%)
Query: 17 AGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQ 76
AGG GTV A+ T P +V+KT+ Q + A+ V +H+ + +
Sbjct: 253 AGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDST---------------WL 297
Query: 77 VLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119
+L+ I + G K LF G P ++ APS A+ + Y K F
Sbjct: 298 LLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 340
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 80.1 bits (196), Expect = 2e-15
Identities = 83/317 (26%), Positives = 136/317 (42%), Gaps = 56/317 (17%)
Query: 17 AGGCGGTVGAIFTCPLEVIKTR--LQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
AG G V P +VIK R LQ RL+ P++ G+
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSD------------------PSAKYHGI 62
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN--GIFVPNSNIVHI 132
Q + IL++EGP + ++G P + AV F + E + ++ VH
Sbjct: 63 LQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF 122
Query: 133 FSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCA-RYVYQTEGIRGFYRGLT 191
G AA + ++P+ +++TR + + K NTL+ A +Y++EG + FY+GL
Sbjct: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGE---PKVYNTLRHAVGTMYRSEGPQVFYKGLA 179
Query: 192 AS------YAGISETIICFAIYESLKKYLKEA-PLASSANGTEKNSTSFFGLMAAAALSK 244
+ YAG+ F+ Y SLK K A P N +N G A +SK
Sbjct: 180 PTLIAIFPYAGLQ-----FSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSG---AGVISK 231
Query: 245 GCASCIAYPHEVIRTRLREEG-----------TKYKSFVQTARLVFREEGYLAFYRGLFA 293
+ YP ++ + RL+ G +YK + A+ V ++EG L F++GL
Sbjct: 232 ----TLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287
Query: 294 QLIRQIPNTAIVLSTYE 310
L++ +T + +YE
Sbjct: 288 SLLKAALSTGFMFFSYE 304
Score = 63.5 bits (153), Expect = 2e-10
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 34/192 (17%)
Query: 13 LHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTP 72
+H GG + + P++V++TR + G V T
Sbjct: 120 VHFVCGGLAACMATLTVHPVDVLRTRFAAQ------------------GEPKVYNT---- 157
Query: 73 GLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIF----VPNSN 128
L + ++ EGP+ ++GL P L+ + P + F+CYS K + N N
Sbjct: 158 -LRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNEN 216
Query: 129 IVHIFSAGSAAFITNSLMNPIWMVKTRMQLE--QKVRGS-----KQMNTLQCARYVYQTE 181
+ ++ A I+ +L P+ + K R+Q+ + R + + + CA+ V Q E
Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
Query: 182 GIRGFYRGLTAS 193
G GF++GL+ S
Sbjct: 277 GALGFFKGLSPS 288
Score = 58.9 bits (141), Expect = 6e-09
Identities = 49/199 (24%), Positives = 86/199 (43%), Gaps = 17/199 (8%)
Query: 126 NSNIVHIFSAGSAA-FITNSLMNPIWMVKTRMQLEQKVRG-----SKQMNTLQCARYVYQ 179
N+ + AGS + +T +L++P ++K R QL+ + +K LQ +R + Q
Sbjct: 12 NNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQ 71
Query: 180 TEGIRGFYRG-LTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMA 238
EG F++G + A I + F +E L + + G+ ++ F
Sbjct: 72 EEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHR--------GSVYDAREFSVHFV 123
Query: 239 AAALSKGCASCIAYPHEVIRTRLREEGTK--YKSFVQTARLVFREEGYLAFYRGLFAQLI 296
L+ A+ +P +V+RTR +G Y + ++R EG FY+GL LI
Sbjct: 124 CGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLI 183
Query: 297 RQIPNTAIVLSTYELIVYL 315
P + S Y + +L
Sbjct: 184 AIFPYAGLQFSCYSSLKHL 202
Score = 44.3 bits (103), Expect = 1e-04
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 15/108 (13%)
Query: 5 GQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGM 64
G++ EN L +L G G + T PL++ K RLQ + QV
Sbjct: 211 GKKNEN-LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR-------- 261
Query: 65 VRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACY 112
GL K +L+KEG F+GL P+L+ A S F Y
Sbjct: 262 ------YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSY 303
Score = 35.0 bits (79), Expect = 0.089
Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
Query: 228 KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLR---------EEGTKYKSFVQTARLV 278
+N+T F + A ++S + P +VI+ R + + KY +Q +R +
Sbjct: 11 RNNTKF-QVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQI 69
Query: 279 FREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLL 316
+EEG AF++G I I A+ ++E++ L+
Sbjct: 70 LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELV 107
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 80.1 bits (196), Expect = 2e-15
Identities = 83/317 (26%), Positives = 136/317 (42%), Gaps = 56/317 (17%)
Query: 17 AGGCGGTVGAIFTCPLEVIKTR--LQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
AG G V P +VIK R LQ RL+ P++ G+
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSD------------------PSAKYHGI 62
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN--GIFVPNSNIVHI 132
Q + IL++EGP + ++G P + AV F + E + ++ VH
Sbjct: 63 LQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF 122
Query: 133 FSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCA-RYVYQTEGIRGFYRGLT 191
G AA + ++P+ +++TR + + K NTL+ A +Y++EG + FY+GL
Sbjct: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGE---PKVYNTLRHAVGTMYRSEGPQVFYKGLA 179
Query: 192 AS------YAGISETIICFAIYESLKKYLKEA-PLASSANGTEKNSTSFFGLMAAAALSK 244
+ YAG+ F+ Y SLK K A P N +N G A +SK
Sbjct: 180 PTLIAIFPYAGLQ-----FSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSG---AGVISK 231
Query: 245 GCASCIAYPHEVIRTRLREEG-----------TKYKSFVQTARLVFREEGYLAFYRGLFA 293
+ YP ++ + RL+ G +YK + A+ V ++EG L F++GL
Sbjct: 232 ----TLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287
Query: 294 QLIRQIPNTAIVLSTYE 310
L++ +T + +YE
Sbjct: 288 SLLKAALSTGFMFFSYE 304
Score = 63.5 bits (153), Expect = 2e-10
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 34/192 (17%)
Query: 13 LHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTP 72
+H GG + + P++V++TR + G V T
Sbjct: 120 VHFVCGGLAACMATLTVHPVDVLRTRFAAQ------------------GEPKVYNT---- 157
Query: 73 GLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIF----VPNSN 128
L + ++ EGP+ ++GL P L+ + P + F+CYS K + N N
Sbjct: 158 -LRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNEN 216
Query: 129 IVHIFSAGSAAFITNSLMNPIWMVKTRMQLE--QKVRGS-----KQMNTLQCARYVYQTE 181
+ ++ A I+ +L P+ + K R+Q+ + R + + + CA+ V Q E
Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
Query: 182 GIRGFYRGLTAS 193
G GF++GL+ S
Sbjct: 277 GALGFFKGLSPS 288
Score = 58.9 bits (141), Expect = 6e-09
Identities = 49/199 (24%), Positives = 86/199 (43%), Gaps = 17/199 (8%)
Query: 126 NSNIVHIFSAGSAA-FITNSLMNPIWMVKTRMQLEQKVRG-----SKQMNTLQCARYVYQ 179
N+ + AGS + +T +L++P ++K R QL+ + +K LQ +R + Q
Sbjct: 12 NNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQ 71
Query: 180 TEGIRGFYRG-LTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMA 238
EG F++G + A I + F +E L + + G+ ++ F
Sbjct: 72 EEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHR--------GSVYDAREFSVHFV 123
Query: 239 AAALSKGCASCIAYPHEVIRTRLREEGTK--YKSFVQTARLVFREEGYLAFYRGLFAQLI 296
L+ A+ +P +V+RTR +G Y + ++R EG FY+GL LI
Sbjct: 124 CGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLI 183
Query: 297 RQIPNTAIVLSTYELIVYL 315
P + S Y + +L
Sbjct: 184 AIFPYAGLQFSCYSSLKHL 202
Score = 44.3 bits (103), Expect = 1e-04
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 15/108 (13%)
Query: 5 GQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGM 64
G++ EN L +L G G + T PL++ K RLQ + QV
Sbjct: 211 GKKNEN-LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR-------- 261
Query: 65 VRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACY 112
GL K +L+KEG F+GL P+L+ A S F Y
Sbjct: 262 ------YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSY 303
Score = 35.0 bits (79), Expect = 0.089
Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
Query: 228 KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLR---------EEGTKYKSFVQTARLV 278
+N+T F + A ++S + P +VI+ R + + KY +Q +R +
Sbjct: 11 RNNTKF-QVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQI 69
Query: 279 FREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLL 316
+EEG AF++G I I A+ ++E++ L+
Sbjct: 70 LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELV 107
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 80.1 bits (196), Expect = 2e-15
Identities = 83/317 (26%), Positives = 136/317 (42%), Gaps = 56/317 (17%)
Query: 17 AGGCGGTVGAIFTCPLEVIKTR--LQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
AG G V P +VIK R LQ RL+ P++ G+
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSD------------------PSAKYHGI 62
Query: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN--GIFVPNSNIVHI 132
Q + IL++EGP + ++G P + AV F + E + ++ VH
Sbjct: 63 LQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF 122
Query: 133 FSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCA-RYVYQTEGIRGFYRGLT 191
G AA + ++P+ +++TR + + K NTL+ A +Y++EG + FY+GL
Sbjct: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGE---PKVYNTLRHAVGTMYRSEGPQVFYKGLA 179
Query: 192 AS------YAGISETIICFAIYESLKKYLKEA-PLASSANGTEKNSTSFFGLMAAAALSK 244
+ YAG+ F+ Y SLK K A P N +N G A +SK
Sbjct: 180 PTLIAIFPYAGLQ-----FSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSG---AGVISK 231
Query: 245 GCASCIAYPHEVIRTRLREEG-----------TKYKSFVQTARLVFREEGYLAFYRGLFA 293
+ YP ++ + RL+ G +YK + A+ V ++EG L F++GL
Sbjct: 232 ----TLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287
Query: 294 QLIRQIPNTAIVLSTYE 310
L++ +T + +YE
Sbjct: 288 SLLKAALSTGFMFFSYE 304
Score = 63.5 bits (153), Expect = 2e-10
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 34/192 (17%)
Query: 13 LHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTP 72
+H GG + + P++V++TR + G V T
Sbjct: 120 VHFVCGGLAACMATLTVHPVDVLRTRFAAQ------------------GEPKVYNT---- 157
Query: 73 GLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIF----VPNSN 128
L + ++ EGP+ ++GL P L+ + P + F+CYS K + N N
Sbjct: 158 -LRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNEN 216
Query: 129 IVHIFSAGSAAFITNSLMNPIWMVKTRMQLE--QKVRGS-----KQMNTLQCARYVYQTE 181
+ ++ A I+ +L P+ + K R+Q+ + R + + + CA+ V Q E
Sbjct: 217 LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276
Query: 182 GIRGFYRGLTAS 193
G GF++GL+ S
Sbjct: 277 GALGFFKGLSPS 288
Score = 58.9 bits (141), Expect = 6e-09
Identities = 49/199 (24%), Positives = 86/199 (43%), Gaps = 17/199 (8%)
Query: 126 NSNIVHIFSAGSAA-FITNSLMNPIWMVKTRMQLEQKVRG-----SKQMNTLQCARYVYQ 179
N+ + AGS + +T +L++P ++K R QL+ + +K LQ +R + Q
Sbjct: 12 NNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQ 71
Query: 180 TEGIRGFYRG-LTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMA 238
EG F++G + A I + F +E L + + G+ ++ F
Sbjct: 72 EEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHR--------GSVYDAREFSVHFV 123
Query: 239 AAALSKGCASCIAYPHEVIRTRLREEGTK--YKSFVQTARLVFREEGYLAFYRGLFAQLI 296
L+ A+ +P +V+RTR +G Y + ++R EG FY+GL LI
Sbjct: 124 CGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLI 183
Query: 297 RQIPNTAIVLSTYELIVYL 315
P + S Y + +L
Sbjct: 184 AIFPYAGLQFSCYSSLKHL 202
Score = 44.3 bits (103), Expect = 1e-04
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 15/108 (13%)
Query: 5 GQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGM 64
G++ EN L +L G G + T PL++ K RLQ + QV
Sbjct: 211 GKKNEN-LQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR-------- 261
Query: 65 VRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACY 112
GL K +L+KEG F+GL P+L+ A S F Y
Sbjct: 262 ------YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSY 303
Score = 35.0 bits (79), Expect = 0.089
Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
Query: 228 KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLR---------EEGTKYKSFVQTARLV 278
+N+T F + A ++S + P +VI+ R + + KY +Q +R +
Sbjct: 11 RNNTKF-QVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQI 69
Query: 279 FREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLL 316
+EEG AF++G I I A+ ++E++ L+
Sbjct: 70 LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELV 107
>gi|157388925 solute carrier family 25, member 38 [Homo sapiens]
Length = 304
Score = 78.6 bits (192), Expect = 7e-15
Identities = 77/312 (24%), Positives = 130/312 (41%), Gaps = 39/312 (12%)
Query: 5 GQQKENTLLH-----LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTI 59
G E +LH G GT + PL+++KTRLQ+ + P H
Sbjct: 16 GDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQ--------PSDH---- 63
Query: 60 SGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119
G+ V G+ VL ++ E L++G+ P++V P +YF K+ F
Sbjct: 64 -GSRRV-------GMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYF 115
Query: 120 NGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCA-RYVY 178
P + + GS + + M+PI ++KTR + G ++ A R +Y
Sbjct: 116 LRGHPPTALESVMLGVGSRS-VAGVCMSPITVIKTRYE-----SGKYGYESIYAALRSIY 169
Query: 179 QTEGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMA 238
+EG RG + GLTA+ + IY K + T T+F +
Sbjct: 170 HSEGHRGLFSGLTAT---LLRDAPFSGIYLMFYNQTKNIVPHDQVDATLIPITNFSCGIF 226
Query: 239 AAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQ 298
A L AS + P +VI+T ++ K++ Q L+F++ G F++G + +R+
Sbjct: 227 AGIL----ASLVTQPADVIKTHMQLYPLKFQWIGQAVTLIFKDYGLRGFFQGGIPRALRR 282
Query: 299 IPNTAIVLSTYE 310
A+ + YE
Sbjct: 283 TLMAAMAWTVYE 294
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 77.0 bits (188), Expect = 2e-14
Identities = 76/344 (22%), Positives = 139/344 (40%), Gaps = 58/344 (16%)
Query: 12 LLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA--------- 62
L + A G G V ++F PL+V+K RLQS R ++ + P L ++S
Sbjct: 12 LQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQST 71
Query: 63 --------GMVRPTSVTP----------------GLFQVLKSILEKEGPKSLFRGLGPNL 98
G++ P + P G I+ EG ++L+ GL L
Sbjct: 72 GKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL 131
Query: 99 VGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQL 158
V P+ A+YF Y + K G + + + + A T ++++P+ +++T++Q
Sbjct: 132 VMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQA 191
Query: 159 EQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL-TASYAGISETIICFAIYESLKKYLKEA 217
+ +++ C R G R + G + + + + + YE +K +L
Sbjct: 192 QHV--SYRELGA--CVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWL--- 244
Query: 218 PLASSANGTE-KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTR----------LREEGT 266
NG K+ TS A +S A+ + P +V++T+ +R
Sbjct: 245 ------NGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPL 298
Query: 267 KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYE 310
S R + E G + G ++I+ P+ AI++STYE
Sbjct: 299 HVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 15/103 (14%)
Query: 17 AGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQ 76
AGG GTV A+ T P +V+KT+ Q + A+ V +H+ + +
Sbjct: 261 AGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDS---------------TWL 305
Query: 77 VLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119
+L+ I + G K LF G P ++ APS A+ + Y K F
Sbjct: 306 LLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 348
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 76.6 bits (187), Expect = 3e-14
Identities = 79/324 (24%), Positives = 135/324 (41%), Gaps = 48/324 (14%)
Query: 5 GQQKENTLLHLFAG---------GCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVH 55
G QK T+ H +G G V T P+++ KTRLQ ++ + +
Sbjct: 25 GHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKY 84
Query: 56 LGTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKA 115
G +F L I ++EG +L+ G+ P L+ A + Y
Sbjct: 85 RG----------------MFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSL 128
Query: 116 KEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKV-RGSKQMNTLQCA 174
K F + ++++ + I++++ NP ++K RMQ + + +GS + +
Sbjct: 129 KRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFID-- 186
Query: 175 RYVYQTEGIRGFYRGL--TASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTS 232
+YQ EG RG +RG+ TA A I + +Y+ KK+L + + T S+
Sbjct: 187 --IYQQEGTRGLWRGVVPTAQRAAIVVGVE-LPVYDITKKHLILSGMMGDTILTHFVSSF 243
Query: 233 FFGLMAAAALSKGCASCIAYPHEVIRTRLREEGT------KYKSFVQTARLVFREEGYLA 286
GL A A + P +V+RTR+ + YK V +++ EG+ A
Sbjct: 244 TCGLAGALA---------SNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFA 294
Query: 287 FYRGLFAQLIRQIPNTAIVLSTYE 310
Y+G + +R P I TYE
Sbjct: 295 LYKGFWPNWLRLGPWNIIFFITYE 318
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 20/127 (15%)
Query: 214 LKEAPLASSANGTEKNST---SFFGLMAAAALSKGCASCIA----YPHEVIRTRLREEGT 266
+K A A +G +K++T GL + G AS +A +P ++ +TRL+ +G
Sbjct: 14 VKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQ 73
Query: 267 ---------KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYE----LIV 313
KY+ + +EEG LA Y G+ L+RQ I + Y+ L V
Sbjct: 74 SIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFV 133
Query: 314 YLLEDRT 320
LED T
Sbjct: 134 ERLEDET 140
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 19/112 (16%)
Query: 5 GQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGM 64
G + L H + G GA+ + P++V++TR+ + R + V ++ GT+ G
Sbjct: 229 GMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHV---DLYKGTVDG--- 282
Query: 65 VRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAK 116
+LK + + EG +L++G PN + + P ++F Y + K
Sbjct: 283 ------------ILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,941,818
Number of Sequences: 37866
Number of extensions: 442690
Number of successful extensions: 1471
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 883
Number of HSP's gapped (non-prelim): 237
length of query: 321
length of database: 18,247,518
effective HSP length: 102
effective length of query: 219
effective length of database: 14,385,186
effective search space: 3150355734
effective search space used: 3150355734
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.