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Search of human proteins with 14149777
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14149777 haloacid dehalogenase-like hydrolase domain
containing 2 [Homo sapiens]
(259 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14149777 haloacid dehalogenase-like hydrolase domain containi... 514 e-146
gi|33636766 phospholysine phosphohistidine inorganic pyrophospha... 194 6e-50
gi|10092677 pyridoxal phosphatase [Homo sapiens] 75 7e-14
gi|108796653 phosphoglycolate phosphatase [Homo sapiens] 72 6e-13
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 34 0.11
gi|13654294 haloacid dehalogenase-like hydrolase domain containi... 34 0.15
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 31 0.94
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 31 1.2
gi|72534838 sorting nexin 6B [Homo sapiens] 31 1.2
gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens] 30 1.6
gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens] 30 1.6
gi|156104908 myosin heavy chain 6 [Homo sapiens] 30 1.6
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 30 2.1
gi|55742693 zyg-11 homolog B [Homo sapiens] 30 2.7
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 30 2.7
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 30 2.7
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 30 2.7
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 30 2.7
gi|23308749 N-acetylneuraminic acid phosphatase [Homo sapiens] 29 3.6
gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens] 29 4.7
>gi|14149777 haloacid dehalogenase-like hydrolase domain containing
2 [Homo sapiens]
Length = 259
Score = 514 bits (1324), Expect = e-146
Identities = 259/259 (100%), Positives = 259/259 (100%)
Query: 1 MAACRALKAVLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERL 60
MAACRALKAVLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERL
Sbjct: 1 MAACRALKAVLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERL 60
Query: 61 RKLEFDISEDEIFTSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTSDPNAVVMGLAPE 120
RKLEFDISEDEIFTSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTSDPNAVVMGLAPE
Sbjct: 61 RKLEFDISEDEIFTSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTSDPNAVVMGLAPE 120
Query: 121 HFHYQILNQAFRLLLDGAPLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKATVVGKP 180
HFHYQILNQAFRLLLDGAPLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKATVVGKP
Sbjct: 121 HFHYQILNQAFRLLLDGAPLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKATVVGKP 180
Query: 181 EKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKINPPP 240
EKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKINPPP
Sbjct: 181 EKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKINPPP 240
Query: 241 YLTCESFPHAVDHILQHLL 259
YLTCESFPHAVDHILQHLL
Sbjct: 241 YLTCESFPHAVDHILQHLL 259
>gi|33636766 phospholysine phosphohistidine inorganic pyrophosphate
phosphatase [Homo sapiens]
Length = 270
Score = 194 bits (493), Expect = 6e-50
Identities = 111/257 (43%), Positives = 158/257 (61%), Gaps = 6/257 (2%)
Query: 7 LKAVLVDLSGTLHIEDA----AVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRK 62
++ VL+D+SG L+ A A+ G+ EA+ RL+ + + +RF TN +++S+ +L+ +L++
Sbjct: 11 VRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKSRAELVGQLQR 70
Query: 63 LEFDISEDEIFTSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTSDPNAVVMGLAPEHF 122
L FDISE E+ AA +L+ + +RP LL+ D +F I TS+PN VV+ A E F
Sbjct: 71 LGFDISEQEVTAPAPAACQILKERGLRPYLLIHDGVRSEFDQIDTSNPNCVVIADAGESF 130
Query: 123 HYQILNQAFRLL--LDGAPLIAIHKARYYKRKDGLALGPGPFVTALEYATDTKATVVGKP 180
YQ +N AF++L L+ LI++ + RYYK GL L GP++ ALEYA KA VVGKP
Sbjct: 131 SYQNMNNAFQVLMELEKPVLISLGRGRYYKETSGLMLDVGPYMKALEYACGIKAEVVGKP 190
Query: 181 EKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTGKYRASDEEKINPPP 240
FF AL+ G E +AVMIGDD DVGGAQ GM + V+TGK+R SDE
Sbjct: 191 SPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRPSDEHHPEVKA 250
Query: 241 YLTCESFPHAVDHILQH 257
++ AVD +LQH
Sbjct: 251 DGYVDNLAEAVDLLLQH 267
>gi|10092677 pyridoxal phosphatase [Homo sapiens]
Length = 296
Score = 74.7 bits (182), Expect = 7e-14
Identities = 67/249 (26%), Positives = 108/249 (43%), Gaps = 22/249 (8%)
Query: 8 KAVLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFD- 66
+ VL D G L + AVPGA E L+RL A FV+N ++ ++ +L R +L F
Sbjct: 20 QGVLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGG 79
Query: 67 ISEDEIFTSLTAARSLLERKQVRP-------MLLVDDRALPDFK--GIQTSDPNAVVMGL 117
+ +++F+S A LL ++ P +L + + + G++ + + G
Sbjct: 80 LRAEQLFSSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDPSAGDGA 139
Query: 118 AP----------EHFHYQILNQAFRLLLDG-APLIAIHKARYYKRKDGLAL-GPGPFVTA 165
AP EHF + L +A L D L+A + ++ DG G G A
Sbjct: 140 APRVRAVLVGYDEHFSFAKLREACAHLRDPECLLVATDRDPWHPLSDGSRTPGTGSLAAA 199
Query: 166 LEYATDTKATVVGKPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGMLGILVKT 225
+E A+ +A VVGKP F +P +M+GD D+ GM +L T
Sbjct: 200 VETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGMTTVLTLT 259
Query: 226 GKYRASDEE 234
G R + +
Sbjct: 260 GVSRLEEAQ 268
>gi|108796653 phosphoglycolate phosphatase [Homo sapiens]
Length = 321
Score = 71.6 bits (174), Expect = 6e-13
Identities = 66/253 (26%), Positives = 103/253 (40%), Gaps = 37/253 (14%)
Query: 10 VLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEF---- 65
+L D G L + AVPGA EAL+ LR + F+TN + +++ E+LR+L F
Sbjct: 31 LLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEKLRRLGFGGPA 90
Query: 66 ------DISEDEIFTSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTS----------- 108
++ T+L + L + +L + + + +
Sbjct: 91 GPGASLEVFGTAYCTALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVASVGVGPEPLQG 150
Query: 109 -------------DPNAVVMGLAPEHFHYQILNQAFRLLLD-GAPLIAIHKARYYKRKDG 154
D AVV+G P HF Y L +A R L G L+ + ++G
Sbjct: 151 EGPGDWLHAPLEPDVRAVVVGFDP-HFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENG 209
Query: 155 LAL-GPGPFVTALEYATDTKATVVGKPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGA 213
+ G G V A+E A +A ++GKP + F + G PE VM+GD D+
Sbjct: 210 RFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLG 269
Query: 214 QDVGMLGILVKTG 226
G+ IL TG
Sbjct: 270 ATCGLKTILTLTG 282
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 34.3 bits (77), Expect = 0.11
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 13 DLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDIS 68
DL G+L E + A ++L G + + T T+ KQ L E+L+K EF++S
Sbjct: 1037 DLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092
>gi|13654294 haloacid dehalogenase-like hydrolase domain containing
3 [Homo sapiens]
Length = 251
Score = 33.9 bits (76), Expect = 0.15
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 146 ARYYKRKDGLALGPGPFVTALEYATDTKATVVGKPEKTFFLEALRGTGCEPEEAVMIGDD 205
+ + +R +G+ G G ++ ++A KP+ F EALR EP A +GD+
Sbjct: 135 SNFDRRLEGILGGLG-LREHFDFVLTSEAAGWPKPDPRIFQEALRLAHMEPVVAAHVGDN 193
Query: 206 CRDDVGGAQDVGMLGILV 223
D G + VGM LV
Sbjct: 194 YLCDYQGPRAVGMHSFLV 211
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 31.2 bits (69), Expect = 0.94
Identities = 19/56 (33%), Positives = 28/56 (50%)
Query: 13 DLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDIS 68
DL G+L E + A ++L G + + T + KQ L E+L K EF+IS
Sbjct: 1036 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEIS 1091
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 30.8 bits (68), Expect = 1.2
Identities = 18/56 (32%), Positives = 29/56 (51%)
Query: 13 DLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDIS 68
DL G+L E + A ++L G + + T + KQ L E+L+K EF++S
Sbjct: 1037 DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMS 1092
>gi|72534838 sorting nexin 6B [Homo sapiens]
Length = 403
Score = 30.8 bits (68), Expect = 1.2
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 3/87 (3%)
Query: 55 DLLERLRKLEFDISEDEIFTSLTAARSLLERKQVRPMLLVDD-RALPDFKGIQTSDPNAV 113
+L ERLRKLE ++ DE R + Q LL RAL D++ + A
Sbjct: 269 ELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKAR 328
Query: 114 VMG--LAPEHFHYQILNQAFRLLLDGA 138
+ P H Q+ Q F L D A
Sbjct: 329 TRNREVRPAESHQQLCCQRFERLSDSA 355
>gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]
Length = 526
Score = 30.4 bits (67), Expect = 1.6
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 9/58 (15%)
Query: 4 CRALKAVLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLR 61
CRA+KA I A+VPG+Q +V+++ +T TK +D+ ERL+
Sbjct: 349 CRAVKATFNPAQDKCGIRLASVPGSQ---------TVVVKEITIHTKLPAKDVYERLK 397
>gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]
Length = 558
Score = 30.4 bits (67), Expect = 1.6
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 9/58 (15%)
Query: 4 CRALKAVLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLR 61
CRA+KA I A+VPG+Q +V+++ +T TK +D+ ERL+
Sbjct: 381 CRAVKATFNPAQDKCGIRLASVPGSQ---------TVVVKEITIHTKLPAKDVYERLK 429
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 30.4 bits (67), Expect = 1.6
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 13 DLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDIS---- 68
DL G+L E + A ++L G + + + K L E+L+K EFDI+
Sbjct: 1035 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNS 1094
Query: 69 --EDEIFTSLTAARSLLERK 86
EDE +L + L E +
Sbjct: 1095 KIEDEQVLALQLQKKLKENQ 1114
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 30.0 bits (66), Expect = 2.1
Identities = 19/79 (24%), Positives = 38/79 (48%)
Query: 13 DLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDISEDEI 72
DL G+L E + A ++L G + + + KQ + E+L+K EF++S+ +
Sbjct: 1037 DLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQA 1096
Query: 73 FTSLTAARSLLERKQVRPM 91
SL +K+++ +
Sbjct: 1097 KIDDEQVHSLQFQKKIKEL 1115
>gi|55742693 zyg-11 homolog B [Homo sapiens]
Length = 744
Score = 29.6 bits (65), Expect = 2.7
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 12 VDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLE-FDISED 70
+D+S T + A+ ++ LK L + +T T D++ L+ L DIS+D
Sbjct: 191 LDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTT---QILDVVRELKHLNHLDISDD 247
Query: 71 EIFTSLTAARSLLERKQVRPMLL 93
+ FTS A R LLE+K + P L+
Sbjct: 248 KQFTSDIALR-LLEQKDILPNLV 269
>gi|219521893 coiled-coil transcriptional coactivator isoform 2
[Homo sapiens]
Length = 606
Score = 29.6 bits (65), Expect = 2.7
Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 18/103 (17%)
Query: 28 AQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDI--------------SEDEIF 73
++ L LR A +++ +E KQ+LLE +RKLE + ++E
Sbjct: 383 SKRELTELRSALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTEDEEAA 442
Query: 74 TSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTSDPNAVVMG 116
L+ +L + + P +D LP + + DP + G
Sbjct: 443 VGLSCPAALTDSEDESP----EDMRLPPYGLCERGDPGSSPAG 481
>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
sapiens]
Length = 691
Score = 29.6 bits (65), Expect = 2.7
Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 18/103 (17%)
Query: 28 AQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDI--------------SEDEIF 73
++ L LR A +++ +E KQ+LLE +RKLE + ++E
Sbjct: 468 SKRELTELRSALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTEDEEAA 527
Query: 74 TSLTAARSLLERKQVRPMLLVDDRALPDFKGIQTSDPNAVVMG 116
L+ +L + + P +D LP + + DP + G
Sbjct: 528 VGLSCPAALTDSEDESP----EDMRLPPYGLCERGDPGSSPAG 566
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 29.6 bits (65), Expect = 2.7
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 13 DLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDIS 68
DL G+L E + A ++L G + + + KQ L E+L+K EF+IS
Sbjct: 1039 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEIS 1094
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 29.6 bits (65), Expect = 2.7
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 13 DLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDIS 68
DL G+L E + A ++L G + + + KQ L E+L+K EF+IS
Sbjct: 1039 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEIS 1094
>gi|23308749 N-acetylneuraminic acid phosphatase [Homo sapiens]
Length = 248
Score = 29.3 bits (64), Expect = 3.6
Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 6/51 (11%)
Query: 174 ATVVG------KPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGM 218
A VVG KP + F G +P + VM+GD D+ G + G+
Sbjct: 153 AVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
>gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 28.9 bits (63), Expect = 4.7
Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 7/108 (6%)
Query: 152 KDGLALGPGPFVTALEYATDTKATVVGKPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVG 211
+DGLA ++ ++ + KPE + L P E V + DD ++
Sbjct: 133 RDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL-DDIGANLK 191
Query: 212 GAQDVGMLGILVKTGKYRASDEEKI------NPPPYLTCESFPHAVDH 253
A+D+GM+ ILV+ + EK+ N P L P + H
Sbjct: 192 PARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,141,404
Number of Sequences: 37866
Number of extensions: 436077
Number of successful extensions: 982
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 965
Number of HSP's gapped (non-prelim): 23
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.