Search of human proteins with 14149653

Search of human proteins with 14149653

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14149653 torsin family 1, member B (torsin B) [Homo sapiens]
         (336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14149653 torsin family 1, member B (torsin B) [Homo sapiens]       682   0.0  
gi|4557541 torsin A [Homo sapiens]                                    467   e-132
gi|145386578 torsin family 2, member A isoform a [Homo sapiens]       274   9e-74
gi|115647957 torsin family 3, member A [Homo sapiens]                 242   3e-64
gi|145386549 torsin family 2, member A isoform b [Homo sapiens]       159   3e-39
gi|197313700 torsin family 2, member A isoform c [Homo sapiens]       159   3e-39
gi|116063568 hypothetical protein LOC54863 [Homo sapiens]              71   1e-12
gi|13540606 caseinolytic peptidase B [Homo sapiens]                    58   1e-08
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]            33   0.28 
gi|21918872 lactation elevated 1 [Homo sapiens]                        30   4.0  
gi|223005897 GPN-loop GTPase 1 isoform a [Homo sapiens]                29   6.8  

>gi|14149653 torsin family 1, member B (torsin B) [Homo sapiens]
          Length = 336

 Score =  682 bits (1759), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREE 60
           MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREE
Sbjct: 1   MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREE 60

Query: 61  RPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQ 120
           RPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQ
Sbjct: 61  RPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQ 120

Query: 121 IVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMD 180
           IVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMD
Sbjct: 121 IVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMD 180

Query: 181 KLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQL 240
           KLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQL
Sbjct: 181 KLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQL 240

Query: 241 KDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAID 300
           KDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAID
Sbjct: 241 KDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAID 300

Query: 301 EDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDFH 336
           EDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDFH
Sbjct: 301 EDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDFH 336


>gi|4557541 torsin A [Homo sapiens]
          Length = 332

 Score =  467 bits (1202), Expect = e-132
 Identities = 222/329 (67%), Positives = 275/329 (83%), Gaps = 4/329 (1%)

Query: 9   GAAALALLLAA-RVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASA 67
           G A L LLL A  VV A EPI++GLA+  A  +TGY+ Y  +YC FAECC ++R L+  A
Sbjct: 4   GRAVLGLLLLAPSVVQAVEPISLGLAL--AGVLTGYI-YPRLYCLFAECCGQKRSLSREA 60

Query: 68  LKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLH 127
           L+ DL++ LFGQHLA ++I  A+ GF NN  PKKPLTLSLHGW GTGKNFVS+I+AEN++
Sbjct: 61  LQKDLDDNLFGQHLAKKIILNAVFGFINNPKPKKPLTLSLHGWTGTGKNFVSKIIAENIY 120

Query: 128 PKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGII 187
             GL S++VHLFV+TLHFPH   I LY+DQLQ WIRGNVSACA S+FIFDEMDK+H G+I
Sbjct: 121 EGGLNSDYVHLFVATLHFPHASNITLYKDQLQLWIRGNVSACARSIFIFDEMDKMHAGLI 180

Query: 188 DAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQLKDLEPVL 247
           DAIKPFLDYY+ VDGVSY+KA+FIFLSNAG + IT  ALDFWR+G++REDI+LKD+E  L
Sbjct: 181 DAIKPFLDYYDLVDGVSYQKAMFIFLSNAGAERITDVALDFWRSGKQREDIKLKDIEHAL 240

Query: 248 SVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAIDEDIVTRV 307
           SV VFNNK+SG WHS LID+NLIDYF+PFLPLEY+H+KMC+R EM++RG  IDEDIV+RV
Sbjct: 241 SVSVFNNKNSGFWHSSLIDRNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYEIDEDIVSRV 300

Query: 308 AEEMTFFPRDEKIYSDKGCKTVQSRLDFH 336
           AEEMTFFP++E+++SDKGCKTV ++LD++
Sbjct: 301 AEEMTFFPKEERVFSDKGCKTVFTKLDYY 329


>gi|145386578 torsin family 2, member A isoform a [Homo sapiens]
          Length = 321

 Score =  274 bits (700), Expect = 9e-74
 Identities = 133/302 (44%), Positives = 191/302 (63%)

Query: 34  IGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGF 93
           +G  SA         + C     C  +   +   L+ DL + L GQHLA  ++ KAL  F
Sbjct: 18  LGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHLAGQHLAKALVVKALKAF 77

Query: 94  RNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKL 153
             +  P KPL LSLHGW GTGK++VS ++A  L   GL+S  VH F   LHFPH   I+ 
Sbjct: 78  VRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIER 137

Query: 154 YQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFL 213
           Y+  L+ W++GN++AC  S+F+FDEMDK+ PG+++ ++PFL     V G +YRKAIFIF+
Sbjct: 138 YKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFIFI 197

Query: 214 SNAGGDLITKTALDFWRAGRKREDIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYF 273
           SN GG+ I + AL+ WR+ R RE+I L++LEPV+S  V +N H G  +SG++++ L+D  
Sbjct: 198 SNTGGEQINQVALEAWRSRRDREEILLQELEPVISRAVLDNPHHGFSNSGIMEERLLDAV 257

Query: 274 IPFLPLEYRHVKMCVRAEMRARGSAIDEDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRL 333
           +PFLPL+  HV+ CV  E+   G    +++V  V +  TFFP DE+++S  GCKTV SR+
Sbjct: 258 VPFLPLQRHHVRHCVLNELAQLGLEPRDEVVQAVLDSTTFFPEDEQLFSSNGCKTVASRI 317

Query: 334 DF 335
            F
Sbjct: 318 AF 319


>gi|115647957 torsin family 3, member A [Homo sapiens]
          Length = 397

 Score =  242 bits (618), Expect = 3e-64
 Identities = 114/290 (39%), Positives = 179/290 (61%), Gaps = 4/290 (1%)

Query: 50  YCRFAECCRE---ERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLS 106
           YC F +CC         N + L+ DL  +L GQHL  +++ + + G+     P+K L LS
Sbjct: 105 YCSFKDCCPRGDCRISNNFTGLEWDLNVRLHGQHLVQQLVLRTVRGYLETPQPEKALALS 164

Query: 107 LHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNV 166
            HGW+GTGKNFV++++ ENL+  GL S+ V +F++T HFPH + + LY++QL   IR   
Sbjct: 165 FHGWSGTGKNFVARMLVENLYRDGLMSDCVRMFIATFHFPHPKYVDLYKEQLMSQIRETQ 224

Query: 167 SACANSVFIFDEMDKLHPGIIDAIKPFLD-YYEQVDGVSYRKAIFIFLSNAGGDLITKTA 225
             C  ++FIFDE +KLHPG+++ + P L+    +         IF+FLSN  GD+I +  
Sbjct: 225 QLCHQTLFIFDEAEKLHPGLLEVLGPHLERRAPEGHRAESPWTIFLFLSNLRGDIINEVV 284

Query: 226 LDFWRAGRKREDIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVK 285
           L   +AG  RE+I ++ LEP L   +     +G  HS L+ +NLIDYFIPFLPLEYRHV+
Sbjct: 285 LKLLKAGWSREEITMEHLEPHLQAEIVETIDNGFGHSRLVKENLIDYFIPFLPLEYRHVR 344

Query: 286 MCVRAEMRARGSAIDEDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDF 335
           +C R    ++     E+ +  +A+ M + P++E+++S +GCK++  R+++
Sbjct: 345 LCARDAFLSQELLYKEETLDEIAQMMVYVPKEEQLFSSQGCKSISQRINY 394


>gi|145386549 torsin family 2, member A isoform b [Homo sapiens]
          Length = 253

 Score =  159 bits (402), Expect = 3e-39
 Identities = 78/180 (43%), Positives = 109/180 (60%)

Query: 34  IGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGF 93
           +G  SA         + C     C  +   +   L+ DL + L GQHLA  ++ KAL  F
Sbjct: 18  LGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHLAGQHLAKALVVKALKAF 77

Query: 94  RNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKL 153
             +  P KPL LSLHGW GTGK++VS ++A  L   GL+S  VH F   LHFPH   I+ 
Sbjct: 78  VRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIER 137

Query: 154 YQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFL 213
           Y+  L+ W++GN++AC  S+F+FDEMDK+ PG+++ ++PFL     V G +YRKAIFIF+
Sbjct: 138 YKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFIFI 197


>gi|197313700 torsin family 2, member A isoform c [Homo sapiens]
          Length = 242

 Score =  159 bits (402), Expect = 3e-39
 Identities = 78/180 (43%), Positives = 109/180 (60%)

Query: 34  IGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGF 93
           +G  SA         + C     C  +   +   L+ DL + L GQHLA  ++ KAL  F
Sbjct: 18  LGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHLAGQHLAKALVVKALKAF 77

Query: 94  RNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKL 153
             +  P KPL LSLHGW GTGK++VS ++A  L   GL+S  VH F   LHFPH   I+ 
Sbjct: 78  VRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIER 137

Query: 154 YQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFL 213
           Y+  L+ W++GN++AC  S+F+FDEMDK+ PG+++ ++PFL     V G +YRKAIFIF+
Sbjct: 138 YKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFIFI 197


>gi|116063568 hypothetical protein LOC54863 [Homo sapiens]
          Length = 423

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 65/277 (23%), Positives = 121/277 (43%), Gaps = 28/277 (10%)

Query: 68  LKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLH 127
           L+  L+  +FGQ  A   I   +  +       +PL L+LHG +G GK+ V +++A +  
Sbjct: 153 LEKALQRAVFGQPAAVSRIVALMRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARHFR 212

Query: 128 PKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSAC----ANSVFIFDEMDKLH 183
                S  V  + +  H P  +  +  +++L + +   V+         + + D+++ + 
Sbjct: 213 SVLEDSALVLQYHARHHCPEARAAQDCREELARRVADVVARAEAEEKTPLLVLDDVELMP 272

Query: 184 PGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTAL-----------DFWRAG 232
             ++D +  FL   +      +  AI++ LS AGG  +T+  L           D +R+ 
Sbjct: 273 RPLLDELHGFL---QPQRSHHFHNAIYVLLSGAGGAEVTRFVLQNASRALPLRPDGFRSA 329

Query: 233 RKREDIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEM 292
                   +DL   L + V + +H  LW +  I        +PFL L+ R V  C R EM
Sbjct: 330 EAAAAQAEEDLRASL-LAVLSREHP-LWQAAAI--------VPFLLLDKRDVVSCFRDEM 379

Query: 293 RARGSAIDEDIVTRVAEEMTFFPRDEKIYSDKGCKTV 329
              G   D+     +A +++F+    + ++  GCK V
Sbjct: 380 AGEGFFPDQARAENLAAQLSFYRVAGREFAVTGCKQV 416


>gi|13540606 caseinolytic peptidase B [Homo sapiens]
          Length = 707

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 51/184 (27%), Positives = 78/184 (42%), Gaps = 20/184 (10%)

Query: 58  REERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNN-KNPKKPLTLSLHGWAGTGKN 116
           RE        L+  L+E + GQ  A   +  A+    N   + + PL     G +G GK 
Sbjct: 329 REAEERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKT 388

Query: 117 FVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQD----------QLQKWIRGNV 166
            +++  A+ +H K  K  F+ L +S     HE    +             QL K ++   
Sbjct: 389 ELAKQTAKYMH-KDAKKGFIRLDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLK--- 444

Query: 167 SACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDG----VSYRKAIFIFLSNAGGDLIT 222
             C N+V +FDE+DK HP ++  +    D     DG    +  + AIFI  SN   D I 
Sbjct: 445 -QCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIA 503

Query: 223 KTAL 226
           + AL
Sbjct: 504 QHAL 507


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 29/141 (20%)

Query: 105 LSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIR- 163
           L LHG  GTGK  +++ VA                ++ L     + I +Y  Q ++ +R 
Sbjct: 740 LLLHGPPGTGKTLLAKAVA------------TECSLTFLSVKGPELINMYVGQSEENVRE 787

Query: 164 --GNVSACANSVFIFDEMDKLHP---------GIIDAIKPFLDYYEQVDGVSYRKAIFIF 212
                 A A  +  FDE+D L P         G++D +   L    ++DG+   + +F+ 
Sbjct: 788 VFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQL--LAELDGLHSTQDVFVI 845

Query: 213 LSNAGGDLITKTALDFWRAGR 233
            +    DL+    L   R GR
Sbjct: 846 GATNRPDLLDPALL---RPGR 863


>gi|21918872 lactation elevated 1 [Homo sapiens]
          Length = 481

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 5/109 (4%)

Query: 36  AASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRN 95
           A +   G L + D   +  E   +E           L E L G ++  E +F  L  F  
Sbjct: 68  ALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFSKL--FSR 125

Query: 96  NKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLH 144
           +K P+    L ++G  GTGK  V  +    +  K  K    H F+  +H
Sbjct: 126 SKPPRG---LYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVH 171


>gi|223005897 GPN-loop GTPase 1 isoform a [Homo sapiens]
          Length = 388

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 27/133 (20%), Positives = 56/133 (42%), Gaps = 15/133 (11%)

Query: 99  PKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKL----- 153
           P+ P+ L + G AG+GK    Q +  +LH +G     ++L  +    P    I +     
Sbjct: 30  PRHPVCLLVLGMAGSGKTTFVQRLTGHLHAQGTPPYVINLDPAVHEVPFPANIDIRDTVK 89

Query: 154 YQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDG---VSYRKAIF 210
           Y++ ++++  G       S+ +F           D +  F++  + +     +     I 
Sbjct: 90  YKEVMKQYGLGPNGGIVTSLNLFATR-------FDQVMKFIEKAQNMSKYVLIDTPGQIE 142

Query: 211 IFLSNAGGDLITK 223
           +F  +A G +IT+
Sbjct: 143 VFTWSASGTIITE 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,001,999
Number of Sequences: 37866
Number of extensions: 508612
Number of successful extensions: 1031
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1018
Number of HSP's gapped (non-prelim): 11
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.