Guide to the Human Genome
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Search of human proteins with 89145417

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89145417 methyltransferase like 7A [Homo sapiens]
         (244 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89145417 methyltransferase like 7A [Homo sapiens]                  513   e-146
gi|164663805 methyltransferase like 7B [Homo sapiens]                 311   3e-85
gi|165932358 methyltransferase like 2A [Homo sapiens]                  47   2e-05
gi|93141204 methyltransferase like 2B [Homo sapiens]                   46   3e-05
gi|118442825 methyltransferase like 6 [Homo sapiens]                   39   0.004
gi|161377433 methyltransferase like 8 [Homo sapiens]                   39   0.005
gi|195927056 alkB, alkylation repair homolog 8 [Homo sapiens]          35   0.046
gi|109389364 arsenic (+3 oxidation state) methyltransferase [Hom...    35   0.078
gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo...    35   0.078
gi|89274169 cytokine induced apoptosis inhibitor 1 [Homo sapiens]      31   1.1  
gi|40018642 hypothetical protein LOC79133 isoform 1 [Homo sapiens]     30   1.5  
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]             29   4.3  
gi|153251913 hypothetical protein LOC57604 isoform 1 [Homo sapiens]    29   4.3  
gi|153945707 endothelin converting enzyme 2 isoform C [Homo sapi...    28   5.6  
gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]     28   7.3  
gi|41872631 fatty acid synthase [Homo sapiens]                         28   9.5  

>gi|89145417 methyltransferase like 7A [Homo sapiens]
          Length = 244

 Score =  513 bits (1320), Expect = e-146
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFS 60
           MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFS
Sbjct: 1   MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFS 60

Query: 61  NLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFE 120
           NLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFE
Sbjct: 61  NLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFE 120

Query: 121 RFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAEC 180
           RFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAEC
Sbjct: 121 RFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAEC 180

Query: 181 STWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVRPHIYG 240
           STWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVRPHIYG
Sbjct: 181 STWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVRPHIYG 240

Query: 241 YAVK 244
           YAVK
Sbjct: 241 YAVK 244


>gi|164663805 methyltransferase like 7B [Homo sapiens]
          Length = 244

 Score =  311 bits (797), Expect = 3e-85
 Identities = 143/244 (58%), Positives = 185/244 (75%)

Query: 1   MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFS 60
           M++ + +L+L + +LT PL+L+  LG W  +CK +FPY +   T   N +M SKKRELFS
Sbjct: 1   MDILVPLLQLLVLLLTLPLHLMALLGCWQPLCKSYFPYLMAVLTPKSNRKMESKKRELFS 60

Query: 61  NLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFE 120
            ++   G SGK++LLE+GCGTGANF+FYPPGCRVTC+DPNP+FEKFL KS+AENRHLQ+E
Sbjct: 61  QIKGLTGASGKVALLELGCGTGANFQFYPPGCRVTCLDPNPHFEKFLTKSMAENRHLQYE 120

Query: 121 RFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAEC 180
           RFVVA GE+M Q+ADGS+DVVVCTLVLCSV++  ++L+EV RVLRPGG  +F EHVA   
Sbjct: 121 RFVVAPGEDMRQLADGSMDVVVCTLVLCSVQSPRKVLQEVRRVLRPGGVLFFWEHVAEPY 180

Query: 181 STWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVRPHIYG 240
            +W + WQQV +P W  + DGC LTRE+WK LE A FS+++++    PL W  V PHI G
Sbjct: 181 GSWAFMWQQVFEPTWKHIGDGCCLTRETWKDLENAQFSEIQMERQPPPLKWLPVGPHIMG 240

Query: 241 YAVK 244
            AVK
Sbjct: 241 KAVK 244


>gi|165932358 methyltransferase like 2A [Homo sapiens]
          Length = 378

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 44/171 (25%), Positives = 72/171 (42%), Gaps = 18/171 (10%)

Query: 44  TVIYNEQMASKKRELFSNLQEFAGPSGKLSLLEVGCGTGANFKF------YPPGCRVTCI 97
           T+   E +  K  +L     EF G S    +LEVGCG G N  F        PG  V C 
Sbjct: 154 TLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVG-NTVFPILQTNNDPGLFVYCC 212

Query: 98  DPNPNFEKFLIKSIAENRHLQFER---FV--VAAGENMHQVADGSVDVVVCTLVLCSV-- 150
           D    F    I+ +  N      R   FV  +   E  + V  GS+D+++   VL ++  
Sbjct: 213 D----FSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLSAIVP 268

Query: 151 KNQERILREVCRVLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDG 201
              ++ +  + R+L+PGG     ++   + +   +   Q L   +++  DG
Sbjct: 269 DKMQKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDG 319


>gi|93141204 methyltransferase like 2B [Homo sapiens]
          Length = 378

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 44/166 (26%), Positives = 70/166 (42%), Gaps = 18/166 (10%)

Query: 49  EQMASKKRELFSNLQEFAGPSGKLSLLEVGCGTGANFKF------YPPGCRVTCIDPNPN 102
           E +  K  +L     EF G S    +LEVGCG G N  F        PG  V C D    
Sbjct: 159 ENVTQKISDLEICADEFPGSSATYRILEVGCGVG-NTVFPILQTNNDPGLFVYCCD---- 213

Query: 103 FEKFLIKSIAENRHLQFER---FV--VAAGENMHQVADGSVDVVVCTLVLCSV--KNQER 155
           F    I+ +  N      R   FV  +   E  + V  GS+D+++   VL +V     ++
Sbjct: 214 FSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLSAVVPDKMQK 273

Query: 156 ILREVCRVLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDG 201
            +  + R+L+PGG     ++   + +   +   Q L   +++  DG
Sbjct: 274 AINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDG 319


>gi|118442825 methyltransferase like 6 [Homo sapiens]
          Length = 284

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 38/158 (24%), Positives = 68/158 (43%), Gaps = 25/158 (15%)

Query: 33  KKWFPYFLVRFTVIYNEQ-MASKKRELFSNLQEFAGPSGKLSLLEVGCGTGANFKFYPPG 91
           K W  ++    T  + ++   +++ E   + +EF     KL++LE GCG G         
Sbjct: 43  KNWDLFYKRNSTNFFKDRHWTTREFEELRSCREFEDQ--KLTMLEAGCGVG--------N 92

Query: 92  CRVTCIDPNPN-------FEKFLIKSIAENRHLQFERFVV-----AAGENMHQVADGSVD 139
           C    ++ +PN       F    I+ + +N     ER  V        + +  V   SVD
Sbjct: 93  CLFPLLEEDPNIFAYACDFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVD 152

Query: 140 VVVCTLVLCSV--KNQERILREVCRVLRPGGAFYFMEH 175
           VV+   VL +V       +L+ + +VL+PG +  F ++
Sbjct: 153 VVMLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDY 190


>gi|161377433 methyltransferase like 8 [Homo sapiens]
          Length = 407

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 39/145 (26%), Positives = 59/145 (40%), Gaps = 23/145 (15%)

Query: 53  SKKRELFSNLQE------------FAGPSGKLSLLEVGCGTG------ANFKFYPPGCRV 94
           SK    FSNL              F G +    +LEVGCG G       N     P   +
Sbjct: 167 SKTESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFL 226

Query: 95  TCIDPNPNFEKFLIKSIAENRHLQFERFV--VAAGENMHQVADGSVDVVVCTLVLCSV-- 150
            C D      + L+KS +  R  Q   FV  V      +   DG +DV++   VL S+  
Sbjct: 227 YCCDFASGAVE-LVKSHSSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLSSIHP 285

Query: 151 KNQERILREVCRVLRPGGAFYFMEH 175
              + ++  + ++L+PGG   F ++
Sbjct: 286 DRMQGVVNRLSKLLKPGGMLLFRDY 310


>gi|195927056 alkB, alkylation repair homolog 8 [Homo sapiens]
          Length = 664

 Score = 35.4 bits (80), Expect = 0.046
 Identities = 40/135 (29%), Positives = 58/135 (42%), Gaps = 27/135 (20%)

Query: 46  IYNE---QMASKKRELFSNLQEF--AGPSGKLSLLEVGCGTGA----NFKFYPPGCRVTC 96
           +Y E     +S +   + ++ EF  A PSG + + ++GCG G     N + Y  GC    
Sbjct: 378 VYEEIAGHFSSTRHTPWPHIVEFLKALPSGSI-VADIGCGNGKYLGINKELYMIGC---- 432

Query: 97  IDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQER- 155
            D + N            R  QF+ FV  A      V  GS D  +   V+      ER 
Sbjct: 433 -DRSQNLVDIC-------RERQFQAFVCDA--LAVPVRSGSCDACISIAVIHHFATAERR 482

Query: 156 --ILREVCRVLRPGG 168
              L+E+ R+LRPGG
Sbjct: 483 VAALQEIVRLLRPGG 497


>gi|109389364 arsenic (+3 oxidation state) methyltransferase [Homo
           sapiens]
          Length = 375

 Score = 34.7 bits (78), Expect = 0.078
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 133 VADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFME-----HVAAECSTWNYFW 187
           + + S D+VV   V+  V +++++L+E  RVL+ GG  YF +      +  E  T    W
Sbjct: 144 IKNESHDIVVSNCVINLVPDKQQVLQEAYRVLKHGGELYFSDVYTSLELPEEIRTHKVLW 203

Query: 188 QQVLDPA 194
            + L  A
Sbjct: 204 GECLGGA 210


>gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo
           sapiens]
          Length = 369

 Score = 34.7 bits (78), Expect = 0.078
 Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 36/149 (24%)

Query: 72  LSLLEVGCGTGANFK-FYPPGCRVTCIDP----------NPNFEKFLIKSIAENRHLQFE 120
           + +L+VGCG G   +     G  V  IDP          + +F+  L K I E R    E
Sbjct: 148 MKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRI-EYRVCSLE 206

Query: 121 RFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFY--------- 171
             V    E          D VV + V+  V + E  L+  C+VL+PGG+ +         
Sbjct: 207 EIVEETAETF--------DAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQL 258

Query: 172 -------FMEHVAAECSTWNYFWQQVLDP 193
                  F E +A+      + W++ + P
Sbjct: 259 SYALGIVFSEQIASIVPKGTHTWEKFVSP 287


>gi|89274169 cytokine induced apoptosis inhibitor 1 [Homo sapiens]
          Length = 312

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)

Query: 135 DGSVDVVVCTLVLCSVK-NQERILREVCRVLRPGGAFYFMEHV 176
           + S D+++  LV  S   +   IL E+ R+LRPGG  +  E V
Sbjct: 57  ESSFDIILSGLVPGSTTLHSAEILAEIARILRPGGCLFLKEPV 99


>gi|40018642 hypothetical protein LOC79133 isoform 1 [Homo sapiens]
          Length = 345

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 15/101 (14%)

Query: 75  LEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENR-----HLQFERFVVAAGEN 129
           L++GCG G   ++                 KF    IAEN        +     V A E 
Sbjct: 94  LDLGCGRGYIAQYLN----------KETIGKFFQADIAENALKNSSETEIPTVSVLADEE 143

Query: 130 MHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAF 170
                + + D+VV +L L  V +  R L ++  +L+P G F
Sbjct: 144 FLPFKENTFDLVVSSLSLHWVNDLPRALEQIHYILKPDGVF 184


>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 2240

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 13/37 (35%), Positives = 18/37 (48%)

Query: 195 WHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSW 231
           W LL +G  +T  +     R  FS      +QAP+SW
Sbjct: 82  WGLLHEGEQITASAPHGRRRCLFSAPSTHRLQAPISW 118


>gi|153251913 hypothetical protein LOC57604 isoform 1 [Homo sapiens]
          Length = 454

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 22/122 (18%)

Query: 59  FSNLQEFAGPSGKLSLLE---------VGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIK 109
           FS+LQ  A P  +  L E         +GCGTG   K       V C    P  E     
Sbjct: 24  FSDLQSKAWPRVRQFLQEQKPGSLIADIGCGTGKYLKVNSQVHTVGCDYCGPLVE----- 78

Query: 110 SIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILR---EVCRVLRP 166
            IA NR  +    +V    N+    D   D ++   V+     ++R +R   E+ RVL P
Sbjct: 79  -IARNRGCEA---MVCDNLNL-PFRDEGFDAIISIGVIHHFSTKQRRIRAIKEMARVLVP 133

Query: 167 GG 168
           GG
Sbjct: 134 GG 135


>gi|153945707 endothelin converting enzyme 2 isoform C [Homo
           sapiens]
          Length = 255

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 15/36 (41%), Positives = 19/36 (52%)

Query: 150 VKNQERILREVCRVLRPGGAFYFMEHVAAECSTWNY 185
           V   +++L EV RVL PGG F  M   A    T +Y
Sbjct: 151 VHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRTRHY 186


>gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]
          Length = 327

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 13/40 (32%), Positives = 22/40 (55%)

Query: 135 DGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFME 174
           D   D+      + +V + ++ L+E  RVL+PGG F  +E
Sbjct: 207 DDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRFLCLE 246


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 40/161 (24%), Positives = 65/161 (40%), Gaps = 34/161 (21%)

Query: 68   PSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQ--------F 119
            PS K+ ++EV  G G  +   P       + P+P  +   +   A +RH Q         
Sbjct: 1236 PSLKMKVVEVLAGHGHLYSRIPG-----LLSPHPLLQ---LSYTATDRHPQALEAAQAEL 1287

Query: 120  ERFVVAAGE----NMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEH 175
            ++  VA G+    +    A GS D++VC   + ++ +    L  +   LR GG  + + H
Sbjct: 1288 QQHDVAQGQWDPADPAPSALGSADLLVCNCAVAALGDPASALSNMVAALREGG--FLLLH 1345

Query: 176  -----------VAAECSTWNYFWQQVL-DPAWHLLFDGCNL 204
                       VA   ST   + Q +L   AW  LF   +L
Sbjct: 1346 TLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESLFSRVSL 1386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,270,119
Number of Sequences: 37866
Number of extensions: 452687
Number of successful extensions: 1059
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1044
Number of HSP's gapped (non-prelim): 16
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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