Guide to the Human Genome
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Search of human proteins with 88759337

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88759337 ATP binding domain 1 family, member B [Homo
sapiens]
         (310 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88759337 ATP binding domain 1 family, member B [Homo sapiens]      629   e-180
gi|21361523 GPN-loop GTPase 3 [Homo sapiens]                          206   3e-53
gi|223005897 GPN-loop GTPase 1 isoform a [Homo sapiens]                90   3e-18
gi|223005899 GPN-loop GTPase 1 isoform b [Homo sapiens]                75   7e-14
gi|223005901 GPN-loop GTPase 1 isoform c [Homo sapiens]                53   4e-07
gi|223005903 GPN-loop GTPase 1 isoform d [Homo sapiens]                44   2e-04
gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens]    34   0.19 
gi|26892295 methylmalonic aciduria type A precursor [Homo sapiens]     33   0.25 
gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]            30   2.7  
gi|5803029 ATP/GTP-binding protein isoform 1 [Homo sapiens]            29   4.7  
gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]            29   4.7  
gi|40254931 hypothetical protein LOC55732 [Homo sapiens]               29   6.1  
gi|56788364 tubulin, gamma complex associated protein 6 [Homo sa...    29   6.1  
gi|46255039 RAD51-like 1 isoform 3 [Homo sapiens]                      28   7.9  
gi|19924117 RAD51-like 1 isoform 2 [Homo sapiens]                      28   7.9  
gi|10835029 RAD51-like 1 isoform 1 [Homo sapiens]                      28   7.9  

>gi|88759337 ATP binding domain 1 family, member B [Homo sapiens]
          Length = 310

 Score =  629 bits (1622), Expect = e-180
 Identities = 310/310 (100%), Positives = 310/310 (100%)

Query: 1   MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDV 60
           MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDV
Sbjct: 1   MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDV 60

Query: 61  GELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTH 120
           GELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTH
Sbjct: 61  GELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTH 120

Query: 121 HGALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKM 180
           HGALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKM
Sbjct: 121 HGALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKM 180

Query: 181 DLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPL 240
           DLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPL
Sbjct: 181 DLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPL 240

Query: 241 NIQDKESIQRVLQAVDKANGYCFRAQEQRSLEAMMSAAMGADFHFSSTLGIQEKYLAPSN 300
           NIQDKESIQRVLQAVDKANGYCFRAQEQRSLEAMMSAAMGADFHFSSTLGIQEKYLAPSN
Sbjct: 241 NIQDKESIQRVLQAVDKANGYCFRAQEQRSLEAMMSAAMGADFHFSSTLGIQEKYLAPSN 300

Query: 301 QSVEQEAMQL 310
           QSVEQEAMQL
Sbjct: 301 QSVEQEAMQL 310


>gi|21361523 GPN-loop GTPase 3 [Homo sapiens]
          Length = 284

 Score =  206 bits (523), Expect = 3e-53
 Identities = 106/254 (41%), Positives = 156/254 (61%), Gaps = 5/254 (1%)

Query: 10  FGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDV 69
           + Q V+GP GSGK+TYC  M +   AL R V VVNLDPA E   Y    D+ EL+ + DV
Sbjct: 4   YAQLVMGPAGSGKSTYCATMVQHCEALNRSVQVVNLDPAAEHFNYSVMADIRELIEVDDV 63

Query: 70  M--DALRLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTHHGALRSI 127
           M  D+LR GPNGGL++CMEY   N DWL   L  +   Y LFDCPGQ+EL TH   ++ +
Sbjct: 64  MEDDSLRFGPNGGLVFCMEYFANNFDWLENCLGHVEDDYILFDCPGQIELYTHLPVMKQL 123

Query: 128 FSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYG 187
             Q+ QW+ R+  V LVDS +  +  KFIS +  +L+ M+ +E+P +N+++KMDL+    
Sbjct: 124 VQQLEQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMISLEIPQVNIMTKMDLLSKKA 183

Query: 188 KLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKES 247
           K    ++ + +  D+  LL+   SD   + +++L + +  LI+DYS+V F+P +  D+ES
Sbjct: 184 KK--EIEKFLDP-DMYSLLEDSTSDLRSKKFKKLTKAICGLIDDYSMVRFLPYDQSDEES 240

Query: 248 IQRVLQAVDKANGY 261
           +   LQ +D A  Y
Sbjct: 241 MNIALQHIDFAIQY 254


>gi|223005897 GPN-loop GTPase 1 isoform a [Homo sapiens]
          Length = 388

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 51/174 (29%), Positives = 91/174 (52%), Gaps = 3/174 (1%)

Query: 14  VIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDAL 73
           V+G  GSGKTT+   ++  L A G    V+NLDPA   +P+   +D+ + V   +VM   
Sbjct: 38  VLGMAGSGKTTFVQRLTGHLHAQGTPPYVINLDPAVHEVPFPANIDIRDTVKYKEVMKQY 97

Query: 74  RLGPNGGLLYCMEYLEANLDWLRAKLDPLR--GHYFLFDCPGQVELCTHHGALRSIFSQM 131
            LGPNGG++  +       D +   ++  +    Y L D PGQ+E+ T   A  +I ++ 
Sbjct: 98  GLGPNGGIVTSLNLFATRFDQVMKFIEKAQNMSKYVLIDTPGQIEVFT-WSASGTIITEA 156

Query: 132 AQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEH 185
                    ++++D+   T+P  F+S +  + + +   +LP I +++K D+I+H
Sbjct: 157 LASSFPTVVIYVMDTSRSTNPVTFMSNMLYACSILYKTKLPFIVVMNKTDIIDH 210


>gi|223005899 GPN-loop GTPase 1 isoform b [Homo sapiens]
          Length = 362

 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 3/155 (1%)

Query: 33  LRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANL 92
           L A G    V+NLDPA   +P+   +D+ + V   +VM    LGPNGG++  +       
Sbjct: 31  LHAQGTPPYVINLDPAVHEVPFPANIDIRDTVKYKEVMKQYGLGPNGGIVTSLNLFATRF 90

Query: 93  DWLRAKLDPLR--GHYFLFDCPGQVELCTHHGALRSIFSQMAQWDLRLTAVHLVDSHYCT 150
           D +   ++  +    Y L D PGQ+E+ T   A  +I ++          ++++D+   T
Sbjct: 91  DQVMKFIEKAQNMSKYVLIDTPGQIEVFT-WSASGTIITEALASSFPTVVIYVMDTSRST 149

Query: 151 DPAKFISVLCTSLATMLHVELPHINLLSKMDLIEH 185
           +P  F+S +  + + +   +LP I +++K D+I+H
Sbjct: 150 NPVTFMSNMLYACSILYKTKLPFIVVMNKTDIIDH 184


>gi|223005901 GPN-loop GTPase 1 isoform c [Homo sapiens]
          Length = 295

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 29/113 (25%), Positives = 58/113 (51%), Gaps = 3/113 (2%)

Query: 75  LGPNGGLLYCMEYLEANLDWLRAKLDPLRG--HYFLFDCPGQVELCTHHGALRSIFSQMA 132
           LGPNGG++  +       D +   ++  +    Y L D PGQ+E+ T   A  +I ++  
Sbjct: 6   LGPNGGIVTSLNLFATRFDQVMKFIEKAQNMSKYVLIDTPGQIEVFTW-SASGTIITEAL 64

Query: 133 QWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEH 185
                   ++++D+   T+P  F+S +  + + +   +LP I +++K D+I+H
Sbjct: 65  ASSFPTVVIYVMDTSRSTNPVTFMSNMLYACSILYKTKLPFIVVMNKTDIIDH 117


>gi|223005903 GPN-loop GTPase 1 isoform d [Homo sapiens]
          Length = 279

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 22/80 (27%), Positives = 44/80 (55%), Gaps = 1/80 (1%)

Query: 106 YFLFDCPGQVELCTHHGALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLAT 165
           Y L D PGQ+E+ T   A  +I ++          ++++D+   T+P  F+S +  + + 
Sbjct: 23  YVLIDTPGQIEVFTW-SASGTIITEALASSFPTVVIYVMDTSRSTNPVTFMSNMLYACSI 81

Query: 166 MLHVELPHINLLSKMDLIEH 185
           +   +LP I +++K D+I+H
Sbjct: 82  LYKTKLPFIVVMNKTDIIDH 101


>gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens]
          Length = 1076

 Score = 33.9 bits (76), Expect = 0.19
 Identities = 27/89 (30%), Positives = 50/89 (56%), Gaps = 7/89 (7%)

Query: 161 TSLATMLHVELPHINLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQ 220
           T ++T L   +P +N  SKM  I+   K +F+L Y    + L+   D  A +PF  H ++
Sbjct: 336 TKVSTHLRTVIPIVNHSSKMT-IQKAIKQSFSLGY----IHLALCADACAGNPFRDHLKK 390

Query: 221 LNEKL-VQLIEDY-SLVSFIPLNIQDKES 247
           LN K+ +QL++ +  L  F+ + + +K++
Sbjct: 391 LNLKVEIQLLDLWQDLQHFLSVLLNNKKN 419


>gi|26892295 methylmalonic aciduria type A precursor [Homo sapiens]
          Length = 418

 Score = 33.5 bits (75), Expect = 0.25
 Identities = 14/41 (34%), Positives = 26/41 (63%)

Query: 9   AFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPAN 49
           AF   + GPPG+GK+T+     + L   G +++V+ +DP++
Sbjct: 143 AFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVDPSS 183


>gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]
          Length = 320

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 13/39 (33%), Positives = 24/39 (61%)

Query: 14  VIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGL 52
           + GPPG+GKTT  L ++  L     + A++ L+ +N+ +
Sbjct: 74  IAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSM 112


>gi|5803029 ATP/GTP-binding protein isoform 1 [Homo sapiens]
          Length = 425

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 14/33 (42%), Positives = 18/33 (54%)

Query: 14  VIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLD 46
           V+GP   GK+T C  +  +   LGRR   V LD
Sbjct: 119 VVGPTDVGKSTVCRLLLNYAVRLGRRPTYVELD 151


>gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
          Length = 354

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 13/37 (35%), Positives = 23/37 (62%)

Query: 14  VIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANE 50
           + GPPG+GKTT  L ++  L     + A++ L+ +N+
Sbjct: 74  IAGPPGTGKTTSILCLARALLGPALKDAMLELNASND 110


>gi|40254931 hypothetical protein LOC55732 [Homo sapiens]
          Length = 853

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 2/108 (1%)

Query: 151 DPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYGKLAFNLDYYTEVL-DLSYLLDHL 209
           DP K I    T   ++L +ELP    L+ +D +   GKL         +L +LS +   L
Sbjct: 642 DP-KLILQAVTLQTSLLKLELPDYVRLAMLDFVSSLGKLFIPEAIQDRILPNLSCMFALL 700

Query: 210 ASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVDK 257
            +D  +   +   E   Q  E  +    +P  +  +E+  +V+  ++K
Sbjct: 701 LADRSWLLEQHTLEAFTQFAEGTNHEEIVPQCLSSEETKNKVVSFLEK 748


>gi|56788364 tubulin, gamma complex associated protein 6 [Homo
           sapiens]
          Length = 1819

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 19/101 (18%), Positives = 43/101 (42%), Gaps = 9/101 (8%)

Query: 209 LASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVDKANGYCFRAQEQ 268
           +A      H R+   +++  + D  +   + L+ + +E  QR+ +   K         +Q
Sbjct: 667 IAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVK---------DQ 717

Query: 269 RSLEAMMSAAMGADFHFSSTLGIQEKYLAPSNQSVEQEAMQ 309
              +A     +  DF ++  L  +E+ L    + +E++A Q
Sbjct: 718 ERRQAARQEELDDDFSYARELRDRERRLKSLEEELERKARQ 758


>gi|46255039 RAD51-like 1 isoform 3 [Homo sapiens]
          Length = 384

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 10/17 (58%), Positives = 13/17 (76%)

Query: 14  VIGPPGSGKTTYCLGMS 30
           + GPPG GKT +C+ MS
Sbjct: 106 ITGPPGCGKTQFCIMMS 122


>gi|19924117 RAD51-like 1 isoform 2 [Homo sapiens]
          Length = 350

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 10/17 (58%), Positives = 13/17 (76%)

Query: 14  VIGPPGSGKTTYCLGMS 30
           + GPPG GKT +C+ MS
Sbjct: 106 ITGPPGCGKTQFCIMMS 122


>gi|10835029 RAD51-like 1 isoform 1 [Homo sapiens]
          Length = 350

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 10/17 (58%), Positives = 13/17 (76%)

Query: 14  VIGPPGSGKTTYCLGMS 30
           + GPPG GKT +C+ MS
Sbjct: 106 ITGPPGCGKTQFCIMMS 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,618,318
Number of Sequences: 37866
Number of extensions: 495865
Number of successful extensions: 1271
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1249
Number of HSP's gapped (non-prelim): 17
length of query: 310
length of database: 18,247,518
effective HSP length: 102
effective length of query: 208
effective length of database: 14,385,186
effective search space: 2992118688
effective search space used: 2992118688
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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