Guide to the Human Genome
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Search of human proteins with 83281450

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83281450 galactosylceramidase isoform a precursor [Homo
sapiens]
         (685 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83281450 galactosylceramidase isoform a precursor [Homo sapiens]  1430   0.0  
gi|83281452 galactosylceramidase isoform b precursor [Homo sapiens]   810   0.0  
gi|38638698 KIAA1199 [Homo sapiens]                                    34   0.51 
gi|4507691 transformation/transcription domain-associated protei...    30   5.7  
gi|197276625 solute carrier family 6 (neurotransmitter transport...    30   9.7  
gi|197276623 solute carrier family 6 (neurotransmitter transport...    30   9.7  
gi|54607094 solute carrier family 6 (neurotransmitter transporte...    30   9.7  
gi|38348296 C-type lectin domain family 4, member G [Homo sapiens]     30   9.7  

>gi|83281450 galactosylceramidase isoform a precursor [Homo sapiens]
          Length = 685

 Score = 1430 bits (3701), Expect = 0.0
 Identities = 685/685 (100%), Positives = 685/685 (100%)

Query: 1   MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGA 60
           MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGA
Sbjct: 1   MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGA 60

Query: 61  VSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYA 120
           VSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYA
Sbjct: 61  VSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYA 120

Query: 121 LDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIV 180
           LDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIV
Sbjct: 121 LDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIV 180

Query: 181 GAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQGLQRVKIIASDNLWESISASMLLD 240
           GAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQGLQRVKIIASDNLWESISASMLLD
Sbjct: 181 GAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQGLQRVKIIASDNLWESISASMLLD 240

Query: 241 AELFKVVDVIGAHYPGTHSAKDAKLTGKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGY 300
           AELFKVVDVIGAHYPGTHSAKDAKLTGKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGY
Sbjct: 241 AELFKVVDVIGAHYPGTHSAKDAKLTGKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGY 300

Query: 301 MTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKT 360
           MTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKT
Sbjct: 301 MTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKT 360

Query: 361 VGHLEKGGSYVALTDGLGNLTIIIETMSHKHSKCIRPFLPYFNVSQQFATFVLKGSFSEI 420
           VGHLEKGGSYVALTDGLGNLTIIIETMSHKHSKCIRPFLPYFNVSQQFATFVLKGSFSEI
Sbjct: 361 VGHLEKGGSYVALTDGLGNLTIIIETMSHKHSKCIRPFLPYFNVSQQFATFVLKGSFSEI 420

Query: 421 PELQVWYTKLGKTSERFLFKQLDSLWLLDSDGSFTLSLHEDELFTLTTLTTGRKGSYPLP 480
           PELQVWYTKLGKTSERFLFKQLDSLWLLDSDGSFTLSLHEDELFTLTTLTTGRKGSYPLP
Sbjct: 421 PELQVWYTKLGKTSERFLFKQLDSLWLLDSDGSFTLSLHEDELFTLTTLTTGRKGSYPLP 480

Query: 481 PKSQPFPSTYKDDFNVDYPFFSEAPNFADQTGVFEYFTNIEDPGEHHFTLRQVLNQRPIT 540
           PKSQPFPSTYKDDFNVDYPFFSEAPNFADQTGVFEYFTNIEDPGEHHFTLRQVLNQRPIT
Sbjct: 481 PKSQPFPSTYKDDFNVDYPFFSEAPNFADQTGVFEYFTNIEDPGEHHFTLRQVLNQRPIT 540

Query: 541 WAADASNTISIIGDYNWTNLTIKCDVYIETPDTGGVFIAGRVNKGGILIRSARGIFFWIF 600
           WAADASNTISIIGDYNWTNLTIKCDVYIETPDTGGVFIAGRVNKGGILIRSARGIFFWIF
Sbjct: 541 WAADASNTISIIGDYNWTNLTIKCDVYIETPDTGGVFIAGRVNKGGILIRSARGIFFWIF 600

Query: 601 ANGSYRVTGDLAGWIIYALGRVEVTAKKWYTLTLTIKGHFTSGMLNDKSLWTDIPVNFPK 660
           ANGSYRVTGDLAGWIIYALGRVEVTAKKWYTLTLTIKGHFTSGMLNDKSLWTDIPVNFPK
Sbjct: 601 ANGSYRVTGDLAGWIIYALGRVEVTAKKWYTLTLTIKGHFTSGMLNDKSLWTDIPVNFPK 660

Query: 661 NGWAAIGTHSFEFAQFDNFLVEATR 685
           NGWAAIGTHSFEFAQFDNFLVEATR
Sbjct: 661 NGWAAIGTHSFEFAQFDNFLVEATR 685


>gi|83281452 galactosylceramidase isoform b precursor [Homo sapiens]
          Length = 407

 Score =  810 bits (2092), Expect = 0.0
 Identities = 387/387 (100%), Positives = 387/387 (100%)

Query: 1   MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGA 60
           MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGA
Sbjct: 1   MAEWLLSASWQRRAKAMTAAAGSAGRAAVPLLLCALLAPGGAYVLDDSDGLGREFDGIGA 60

Query: 61  VSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYA 120
           VSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYA
Sbjct: 61  VSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYA 120

Query: 121 LDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIV 180
           LDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIV
Sbjct: 121 LDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIV 180

Query: 181 GAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQGLQRVKIIASDNLWESISASMLLD 240
           GAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQGLQRVKIIASDNLWESISASMLLD
Sbjct: 181 GAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNYQGLQRVKIIASDNLWESISASMLLD 240

Query: 241 AELFKVVDVIGAHYPGTHSAKDAKLTGKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGY 300
           AELFKVVDVIGAHYPGTHSAKDAKLTGKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGY
Sbjct: 241 AELFKVVDVIGAHYPGTHSAKDAKLTGKKLWSSEDFSTLNSDMGAGCWGRILNQNYINGY 300

Query: 301 MTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKT 360
           MTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKT
Sbjct: 301 MTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKT 360

Query: 361 VGHLEKGGSYVALTDGLGNLTIIIETM 387
           VGHLEKGGSYVALTDGLGNLTIIIETM
Sbjct: 361 VGHLEKGGSYVALTDGLGNLTIIIETM 387


>gi|38638698 KIAA1199 [Homo sapiens]
          Length = 1361

 Score = 33.9 bits (76), Expect = 0.51
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 15/95 (15%)

Query: 51  LGREFDGIGAVSGGGATSRLLVNYPE------PYRSQILDYLFKPNFGASL--------- 95
           +G E DG+   +  G  SR ++   E      PYR+ I ++     FG  +         
Sbjct: 478 IGEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAA 537

Query: 96  HILKVEIGGDGQTTDGTEPSHMHYALDENYFRGYE 130
           H+   E+   GQ   G  P H H A D +   GY+
Sbjct: 538 HLEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYD 572


>gi|4507691 transformation/transcription domain-associated protein
            [Homo sapiens]
          Length = 3830

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 5/48 (10%)

Query: 424  QVWYTKLGKT-SERFLFKQLDSLWLLDSDGSFTLSLHEDELFTLTTLT 470
            Q WY KLG   S +FL ++L   W+L +  +F  +L    LF +  LT
Sbjct: 1152 QAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKAL----LFVMMDLT 1195


>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform b [Homo sapiens]
          Length = 200

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 26/94 (27%)

Query: 281 SDMGAGCWGRI------------LNQNYINGYMTSTIAWN---LVASYYEQLPYGRCGLM 325
           S+ G  CW +I            +  + +N Y    +AW    L  S+ ++LP+  C   
Sbjct: 106 SEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCN-- 163

Query: 326 TAQEPWSGHYVVESP------VWVSAHTTQFTQP 353
                W+  + +E        VW++  +T FT P
Sbjct: 164 ---HSWNTPHCMEDTMRKNKSVWITISSTNFTSP 194


>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 26/94 (27%)

Query: 281 SDMGAGCWGRI------------LNQNYINGYMTSTIAWN---LVASYYEQLPYGRCGLM 325
           S+ G  CW +I            +  + +N Y    +AW    L  S+ ++LP+  C   
Sbjct: 106 SEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCN-- 163

Query: 326 TAQEPWSGHYVVESP------VWVSAHTTQFTQP 353
                W+  + +E        VW++  +T FT P
Sbjct: 164 ---HSWNTPHCMEDTMRKNKSVWITISSTNFTSP 194


>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 26/94 (27%)

Query: 281 SDMGAGCWGRI------------LNQNYINGYMTSTIAWN---LVASYYEQLPYGRCGLM 325
           S+ G  CW +I            +  + +N Y    +AW    L  S+ ++LP+  C   
Sbjct: 106 SEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCN-- 163

Query: 326 TAQEPWSGHYVVESP------VWVSAHTTQFTQP 353
                W+  + +E        VW++  +T FT P
Sbjct: 164 ---HSWNTPHCMEDTMRKNKSVWITISSTNFTSP 194


>gi|38348296 C-type lectin domain family 4, member G [Homo sapiens]
          Length = 293

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 24/105 (22%), Positives = 38/105 (36%), Gaps = 26/105 (24%)

Query: 578 IAGRVNKGGILIRSARGIFFWIFANGSYRVTGDLAGWIIYALGRVEVTAKKWYTLTLTIK 637
           I G +++ G L R+ RG  +W+                +  LG+V+    +W        
Sbjct: 202 IVGGLDEQGFLTRNTRGRGYWLGLRA------------VRHLGKVQ--GYQWVDGVSLSF 247

Query: 638 GHFTSGMLNDK------------SLWTDIPVNFPKNGWAAIGTHS 670
            H+  G  ND              LW D P +  K+GW     H+
Sbjct: 248 SHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWICEKRHN 292


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,185,456
Number of Sequences: 37866
Number of extensions: 1248197
Number of successful extensions: 2390
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2387
Number of HSP's gapped (non-prelim): 8
length of query: 685
length of database: 18,247,518
effective HSP length: 109
effective length of query: 576
effective length of database: 14,120,124
effective search space: 8133191424
effective search space used: 8133191424
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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