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Search of human proteins with 82775373
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 681 0.0
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 455 e-128
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 111 1e-24
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 110 2e-24
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 109 4e-24
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 102 6e-22
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 102 6e-22
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 100 2e-21
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 99 4e-21
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 99 7e-21
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 98 1e-20
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 97 2e-20
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 97 2e-20
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 96 5e-20
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 93 3e-19
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 93 3e-19
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 93 3e-19
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 93 3e-19
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 93 3e-19
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 93 3e-19
gi|115430257 solute carrier family 25, member 26 [Homo sapiens] 92 7e-19
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 91 2e-18
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 89 6e-18
gi|157388925 solute carrier family 25, member 38 [Homo sapiens] 87 2e-17
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 87 2e-17
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 87 2e-17
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 87 2e-17
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 87 2e-17
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 87 3e-17
gi|13899342 solute carrier [Homo sapiens] 86 6e-17
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 681 bits (1757), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEH 60
MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEH
Sbjct: 1 MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEH 60
Query: 61 SVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM 120
SVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM
Sbjct: 61 SVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM 120
Query: 121 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRS 180
YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRS
Sbjct: 121 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRS 180
Query: 181 AISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIIS 240
AISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIIS
Sbjct: 181 AISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIIS 240
Query: 241 GGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFK 300
GGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFK
Sbjct: 241 GGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFK 300
Query: 301 GIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 338
GIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY
Sbjct: 301 GIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 338
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 455 bits (1170), Expect = e-128
Identities = 218/328 (66%), Positives = 262/328 (79%), Gaps = 11/328 (3%)
Query: 19 GDSRDGGGGK----------DATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDS 68
G R GGG+ D DYE LP A+V+THM AGA+AGILEH VMYP+D
Sbjct: 36 GVGRGAGGGEAGACRPPVRQDPDSGPDYEALPAGATVTTHMVAGAVAGILEHCVMYPIDC 95
Query: 69 VKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENM 128
VKTRMQSL PDP A+Y ++ AL +I+RTEG WRP+RG+NV GAGPAHA+YFACYE +
Sbjct: 96 VKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKL 155
Query: 129 KRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTV 188
K+TL+DV H GNSH+ANG AG +ATLLHDA MNPAEVVKQR+QMYNS + C+R V
Sbjct: 156 KKTLSDVIHPGGNSHIANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAV 215
Query: 189 WRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIISGGLAGALA 248
W+ EG GAFYRSYTTQLTMN+PFQ+IHF+TYEFLQE NP R YNP SH++SG AGA+A
Sbjct: 216 WQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRRYNPSSHVLSGACAGAVA 275
Query: 249 AAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIY 308
AAATTPLDVCKTLLNTQE++AL+ ++I+G ++GMA+AFRTVYQ+ G+ YF+G+QARVIY
Sbjct: 276 AAATTPLDVCKTLLNTQESLALN-SHITGHITGMASAFRTVYQVGGVTAYFRGVQARVIY 334
Query: 309 QMPSTAISWSVYEFFKYFLTKRQLENRA 336
Q+PSTAI+WSVYEFFKY +TKRQ E RA
Sbjct: 335 QIPSTAIAWSVYEFFKYLITKRQEEWRA 362
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 111 bits (277), Expect = 1e-24
Identities = 85/305 (27%), Positives = 137/305 (44%), Gaps = 30/305 (9%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPD---PKAQYTSIYGA-------------L 91
H+ AG G + + P++ VKTR+QS S + Q ++ GA L
Sbjct: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
Query: 92 KKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGS 151
K I+ EG RG+ ++G P+ A+YFA Y N K LNDVF +S + I+ +
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVF--DPDSTQVHMISAA 126
Query: 152 MATLLHDAVMNPAEVVKQRLQM----YNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTM 207
MA NP ++K RLQ+ + A C+R V++T+GL FYR +
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYA- 185
Query: 208 NIPFQSIHFITYEFLQEQVNPHRT-----YNPQSHIISGGLAGALAAAATTPLDVCKTLL 262
I IHF+ YE +++++ ++T + +S + G + AAAT+ C T +
Sbjct: 186 GISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATS--KTCATTI 243
Query: 263 NTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEF 322
V L + + Q G ++G+ ++ Q+P+TAI + YE
Sbjct: 244 AYPHVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYEL 303
Query: 323 FKYFL 327
Y L
Sbjct: 304 VVYLL 308
Score = 62.8 bits (151), Expect = 4e-10
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 13/195 (6%)
Query: 44 SVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRP 103
S HM + AMAG + P+ +KTR+Q + + + + ++K+ +T+G
Sbjct: 117 STQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGF 176
Query: 104 LRGVNVMIMGAGPAHAMYFACYENMKRTL-----------NDVFHHQGNSHLANGIAGSM 152
RG++ G ++F YE++K+ L ++ + + + +A +
Sbjct: 177 YRGMSASYAGISET-VIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT 235
Query: 153 ATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQ 212
+ + P VV+ RL+ +++RS + + + EG G+ YR TT L IP
Sbjct: 236 SKTCATTIAYP-HVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNT 294
Query: 213 SIHFITYEFLQEQVN 227
+I TYE + +N
Sbjct: 295 AIMMATYELVVYLLN 309
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 110 bits (274), Expect = 2e-24
Identities = 83/304 (27%), Positives = 133/304 (43%), Gaps = 27/304 (8%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPD---PKAQYTSIYGA-------------L 91
H+ AG G + + P++ VKTR+QS S + Q ++ GA L
Sbjct: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
Query: 92 KKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGS 151
K I+ EG RG+ ++G P+ A+YFA Y N K LNDVF +S + I+ +
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVF--DPDSTQVHMISAA 126
Query: 152 MATLLHDAVMNPAEVVKQRLQM----YNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTM 207
MA NP ++K RLQ+ + A C+R V++T+GL FYR +
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYA- 185
Query: 208 NIPFQSIHFITYEFLQEQVNPHRT----YNPQSHIISGGLAGALAAAATTPLDVCKTLLN 263
I IHF+ YE +++++ ++T N + + + AA T T+
Sbjct: 186 GISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAY 245
Query: 264 TQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFF 323
E V L + + Q G ++G+ ++ Q+P+TAI + YE
Sbjct: 246 PHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELV 305
Query: 324 KYFL 327
Y L
Sbjct: 306 VYLL 309
Score = 68.6 bits (166), Expect = 8e-12
Identities = 47/195 (24%), Positives = 89/195 (45%), Gaps = 12/195 (6%)
Query: 44 SVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRP 103
S HM + AMAG + P+ +KTR+Q + + + + ++K+ +T+G
Sbjct: 117 STQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGF 176
Query: 104 LRGVNVMIMGAGPAHAMYFACYENMKRTL-----------NDVFHHQGNSHLANGIAGSM 152
RG++ G ++F YE++K+ L ++ + + + +A +
Sbjct: 177 YRGMSASYAGISET-VIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT 235
Query: 153 ATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQ 212
+ + P EVV+ RL+ +++RS + + + EG G+ YR TT L IP
Sbjct: 236 SKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNT 295
Query: 213 SIHFITYEFLQEQVN 227
+I TYE + +N
Sbjct: 296 AIMMATYELVVYLLN 310
Score = 37.0 bits (84), Expect = 0.025
Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 30 ATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYG 89
+T D E++ ++ M A A + ++ YP + V+TR++ + +Y S +
Sbjct: 211 STMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLR----EEGTKYRSFFQ 266
Query: 90 ALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLN 133
L +++ EG+ RG+ ++ P A+ A YE + LN
Sbjct: 267 TLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLN 310
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 109 bits (272), Expect = 4e-24
Identities = 90/328 (27%), Positives = 143/328 (43%), Gaps = 37/328 (11%)
Query: 30 ATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPD------PKAQ 83
ATG + EN H+ AG G + P++ +KTR+QS P+
Sbjct: 2 ATGGQQKEN------TLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVH 55
Query: 84 YTSIYGA---------------LKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENM 128
+I GA LK I+ EG RG+ ++G P+ A+YFACY
Sbjct: 56 LGTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKA 115
Query: 129 KRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM----YNSQHRSAISC 184
K N +F NS++ + + A + +++MNP +VK R+Q+ S+ + + C
Sbjct: 116 KEQFNGIF--VPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQC 173
Query: 185 IRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVN--PHRTYNPQSHIISGG 242
R V++TEG+ FYR T I I F YE L++ + P + + S
Sbjct: 174 ARYVYQTEGIRGFYRGLTASYA-GISETIICFAIYESLKKYLKEAPLASSANGTEKNSTS 232
Query: 243 LAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGI 302
G +AAAA + + E + L + R V++ G +++G+
Sbjct: 233 FFGLMAAAALSK-GCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGL 291
Query: 303 QARVIYQMPSTAISWSVYEFFKYFLTKR 330
A++I Q+P+TAI S YE Y L R
Sbjct: 292 FAQLIRQIPNTAIVLSTYELIVYLLEDR 319
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 102 bits (253), Expect = 6e-22
Identities = 83/284 (29%), Positives = 126/284 (44%), Gaps = 25/284 (8%)
Query: 52 GAMAGILEHSVMYPVDSVKTRMQSL----SPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
G++AG + + +YP+D VKTRMQ+ S + Y + + KK++R EGF+ RG+
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
Query: 108 NVMIMGAGPAHAMYFACYENMKRTLND-----VFHHQGNSHLANGI-AGSMATLLHDAVM 161
++G P A +K T+ND H G+ LA I AG A
Sbjct: 395 LPQLLGVAPEKA--------IKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFT 446
Query: 162 NPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEF 221
NP E+VK RLQ+ +V R G Y+ +IPF +I+F Y
Sbjct: 447 NPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAH 506
Query: 222 LQEQ-VNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
++ N +P S +++G +AG AA+ TP DV KT L + S
Sbjct: 507 VKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQT------TYS 560
Query: 281 GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
G+ + FR + + G +KG ARV P ++ YE +
Sbjct: 561 GVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 604
Score = 45.8 bits (107), Expect = 5e-05
Identities = 25/95 (26%), Positives = 46/95 (48%)
Query: 36 YENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIM 95
+ N S + + AGA+AG+ S++ P D +KTR+Q + + Y+ + +KI+
Sbjct: 511 FANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKIL 570
Query: 96 RTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKR 130
R EG +G + + P + YE ++R
Sbjct: 571 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 102 bits (253), Expect = 6e-22
Identities = 83/284 (29%), Positives = 126/284 (44%), Gaps = 25/284 (8%)
Query: 52 GAMAGILEHSVMYPVDSVKTRMQSL----SPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
G++AG + + +YP+D VKTRMQ+ S + Y + + KK++R EGF+ RG+
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395
Query: 108 NVMIMGAGPAHAMYFACYENMKRTLND-----VFHHQGNSHLANGI-AGSMATLLHDAVM 161
++G P A +K T+ND H G+ LA I AG A
Sbjct: 396 LPQLLGVAPEKA--------IKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFT 447
Query: 162 NPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEF 221
NP E+VK RLQ+ +V R G Y+ +IPF +I+F Y
Sbjct: 448 NPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAH 507
Query: 222 LQEQ-VNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
++ N +P S +++G +AG AA+ TP DV KT L + S
Sbjct: 508 VKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQT------TYS 561
Query: 281 GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
G+ + FR + + G +KG ARV P ++ YE +
Sbjct: 562 GVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 605
Score = 45.8 bits (107), Expect = 5e-05
Identities = 25/95 (26%), Positives = 46/95 (48%)
Query: 36 YENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIM 95
+ N S + + AGA+AG+ S++ P D +KTR+Q + + Y+ + +KI+
Sbjct: 512 FANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKIL 571
Query: 96 RTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKR 130
R EG +G + + P + YE ++R
Sbjct: 572 REEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 100 bits (249), Expect = 2e-21
Identities = 75/282 (26%), Positives = 129/282 (45%), Gaps = 18/282 (6%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
+ +GAMAG + + P+D K MQ S K +T++ G L+ +++ GF RG
Sbjct: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSS--KTNFTNLLGGLQSMVQEGGFRSLWRGNG 153
Query: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-AGSMATLLHDAVMNPAEVV 167
+ ++ P +A+ F+ +E K + QG+ + AGS+A + ++NP EV+
Sbjct: 154 INVLKIAPEYAIKFSVFEQCKNYFCGI---QGSPPFQERLLAGSLAVAISQTLINPMEVL 210
Query: 168 KQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQ-EQ 225
K RL + + Q++ + C R + + EG A YR Y + IP+ YE LQ
Sbjct: 211 KTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFW 270
Query: 226 VNPHRTYNPQSHIISGG---LAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM 282
V R S ++S L+ A+ PL + +T + Q+ V G M
Sbjct: 271 VKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV-------EGSNPTM 323
Query: 283 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
+ + G G ++G+ ++ +P+ IS+ VYE K
Sbjct: 324 RGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMK 365
Score = 45.1 bits (105), Expect = 9e-05
Identities = 37/185 (20%), Positives = 80/185 (43%), Gaps = 12/185 (6%)
Query: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHR--SAISCIRTVWRTEGLGAFYRSYTTQL 205
++G+MA + P + K +Q+Y+S+ + + ++++ + G + +R +
Sbjct: 97 LSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINV 156
Query: 206 TMNIPFQSIHFITYEFLQEQVNPHRTYNP-QSHIISGGLAGALAAAATTPLDVCKTLLNT 264
P +I F +E + + P Q +++G LA A++ P++V KT L
Sbjct: 157 LKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTL 216
Query: 265 QENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
+ +G+ G+ + R + Q G ++G ++ +P +VYE +
Sbjct: 217 RR---------TGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQ 267
Query: 325 YFLTK 329
F K
Sbjct: 268 CFWVK 272
Score = 42.7 bits (99), Expect = 5e-04
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 35 DYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKI 94
D L + +SV+ T G MA YP+ V+TRMQ+ + ++ G L++I
Sbjct: 279 DPSGLVSLSSVTLSTTCGQMAS-------YPLTLVRTRMQA-QDTVEGSNPTMRGVLQRI 330
Query: 95 MRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTL 132
+ +G+ RG+ ++ PA + + YE MK+TL
Sbjct: 331 LAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/180 (21%), Positives = 80/180 (44%), Gaps = 7/180 (3%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
+ AG++A + +++ P++ +KTR L+ QY + ++I++ EG RG
Sbjct: 190 LLAGSLAVAISQTLINPMEVLKTR---LTLRRTGQYKGLLDCARQILQREGTRALYRGYL 246
Query: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGN-SHLANGIAGSMATLLHDAVMNPAEVV 167
++G P A YE ++ G+ S L + + +++T P +V
Sbjct: 247 PNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLV 306
Query: 168 KQRLQMYNSQHRSAISC---IRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQE 224
+ R+Q ++ S + ++ + +G YR T L +P I ++ YE +++
Sbjct: 307 RTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 99.4 bits (246), Expect = 4e-21
Identities = 76/286 (26%), Positives = 129/286 (45%), Gaps = 18/286 (6%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
+ AGA+AG + + P+D +K MQ + K +I G L+ ++ G RG
Sbjct: 189 LVAGAVAGAVSRTGTAPLDRLKVFMQVHAS--KTNRLNILGGLRSMVLEGGIRSLWRGNG 246
Query: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANG-IAGSMATLLHDAVMNPAEVV 167
+ ++ P A+ F YE +KR + Q H+ +AGS+A ++ P EV+
Sbjct: 247 INVLKIAPESAIKFMAYEQIKRA---ILGQQETLHVQERFVAGSLAGATAQTIIYPMEVL 303
Query: 168 KQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQE-- 224
K RL + + Q++ + C R + EG AFYR Y + IP+ I YE L+
Sbjct: 304 KTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWW 363
Query: 225 -QVNPHRTYNPQSHII--SGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSG 281
Q H + +P ++ G ++ A+ PL + +T + Q ++ G
Sbjct: 364 LQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE------GGPQLS 417
Query: 282 MANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
M R + G+ G ++GI + +P+ +IS+ VYE K L
Sbjct: 418 MLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 9/186 (4%)
Query: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
V AG++AG +++YP++ +KTR L+ QY + ++I+ EG
Sbjct: 279 VQERFVAGSLAGATAQTIIYPMEVLKTR---LTLRRTGQYKGLLDCARRILEREGPRAFY 335
Query: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSH--LANGIAGSMATLLHDAVMN 162
RG ++G P + A YE +K + H L G++++
Sbjct: 336 RGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASY 395
Query: 163 PAEVVKQRLQMYNS----QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFIT 218
P +V+ R+Q S S + +R + EG+ YR IP SI ++
Sbjct: 396 PLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVV 455
Query: 219 YEFLQE 224
YE +++
Sbjct: 456 YENMKQ 461
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/99 (26%), Positives = 44/99 (44%)
Query: 34 EDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKK 93
+ Y + + + G ++ YP+ V+TRMQ+ + S+ G L+
Sbjct: 365 QQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRH 424
Query: 94 IMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTL 132
I+ EG RG+ M PA ++ + YENMK+ L
Sbjct: 425 ILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 98.6 bits (244), Expect = 7e-21
Identities = 83/299 (27%), Positives = 127/299 (42%), Gaps = 37/299 (12%)
Query: 43 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQ----SLSPDPKAQYTSIYGALKKIMRTE 98
A + T G++AG + + +YP+D VKTRMQ S S + Y + + KK++R E
Sbjct: 324 AESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYE 383
Query: 99 GFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSH----------LANGI 148
GF+ RG+ ++G P A +K T+ND + LA G
Sbjct: 384 GFFGLYRGLIPQLIGVAPEKA--------IKLTVNDFVRDKFTRRDGSVPLPAEVLAGGC 435
Query: 149 AGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMN 208
AG + NP E+VK RLQ+ V R G+ Y+ +
Sbjct: 436 AGGSQVIF----TNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRD 491
Query: 209 IPFQSIHFITY---EFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQ 265
IPF +I+F Y + L N H + + +G +AG AA+ TP DV KT L
Sbjct: 492 IPFSAIYFPVYAHCKLLLADENGH--VGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVA 549
Query: 266 ENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
+ SG+ + FR + + G + ++KG ARV P ++ YE +
Sbjct: 550 ARAGQT------TYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQ 602
Score = 48.1 bits (113), Expect = 1e-05
Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEG---FWRPLR 105
+ AGAMAG+ S++ P D +KTR+Q + + Y+ + +KI+R EG FW +
Sbjct: 522 LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFW---K 578
Query: 106 GVNVMIMGAGPAHAMYFACYENMKR 130
G + + P + YE ++R
Sbjct: 579 GTAARVFRSSPQFGVTLVTYELLQR 603
Score = 42.4 bits (98), Expect = 6e-04
Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 241 GGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFK 300
G +AGA+ A A P+D+ KT + Q + + + S + F+ V + G G ++
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNS--FDCFKKVLRYEGFFGLYR 390
Query: 301 GIQARVIYQMPSTAISWSVYEFFKYFLTKR 330
G+ ++I P AI +V +F + T+R
Sbjct: 391 GLIPQLIGVAPEKAIKLTVNDFVRDKFTRR 420
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 97.8 bits (242), Expect = 1e-20
Identities = 84/310 (27%), Positives = 140/310 (45%), Gaps = 30/310 (9%)
Query: 33 SEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALK 92
S Y LP+S ST G+LE + P + R + DP ++T A
Sbjct: 58 SLSYTKLPSSLQ-STGKCLLYCNGVLEPLYLCPNGA---RCATWFQDP-TRFTGTMDAFV 112
Query: 93 KIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTL------NDVFHHQGNSHLAN 146
KI+R EG G+ ++ PA A+YF Y+ +K L +D++ A
Sbjct: 113 KIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLY--------AP 164
Query: 147 GIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLT 206
+AG++A L V++P E+++ +LQ + +R +C+RT G + + +
Sbjct: 165 MVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
Query: 207 MNIPFQSIHFITYEFLQEQVNPHRTYNPQS---HIISGGLAGALAAAATTPLDVCKT--- 260
++PF ++++ YE ++ +N R + S ++GG++G +AA T P DV KT
Sbjct: 225 RDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQ 284
Query: 261 -LLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSV 319
L E V ++ ++ R + +G G F G R+I PS AI S
Sbjct: 285 VALGAMEAVRVNPLHVDSTWL----LLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMIST 340
Query: 320 YEFFKYFLTK 329
YEF K F +
Sbjct: 341 YEFGKSFFQR 350
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/55 (30%), Positives = 30/55 (54%)
Query: 278 RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQL 332
R +G +AF + + G + G+ A ++ +P+TAI ++ Y+ K FL R L
Sbjct: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL 157
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 97.4 bits (241), Expect = 2e-20
Identities = 79/289 (27%), Positives = 128/289 (44%), Gaps = 24/289 (8%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
+ AG +AG + + P+D +K MQ K+ +I+G +++++ G RG
Sbjct: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS--KSDKMNIFGGFRQMVKEGGIRSLWRGNG 255
Query: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVK 168
++ P A+ F YE K+ L + G I+GSMA + P EV+K
Sbjct: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGT--FERFISGSMAGATAQTFIYPMEVMK 313
Query: 169 QRLQMYNSQHRSAI-SCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE------- 220
RL + + S I C + + + EGLGAFY+ Y L IP+ I YE
Sbjct: 314 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373
Query: 221 --FLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR 278
F ++ VNP + G L+ A+ PL + +T + Q ++ S +
Sbjct: 374 DNFAKDSVNP----GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ-----AMLEGSPQ 424
Query: 279 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
L+ M FR + G+ G ++GI + +P+ IS+ VYE K L
Sbjct: 425 LN-MVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 8/92 (8%)
Query: 238 IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAG 297
+++GG+AGA++ +T PLD K ++ + + + NI G FR + + G+
Sbjct: 198 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-NIFG-------GFRQMVKEGGIRS 249
Query: 298 YFKGIQARVIYQMPSTAISWSVYEFFKYFLTK 329
++G VI P TA+ + YE +K LT+
Sbjct: 250 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTE 281
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 97.4 bits (241), Expect = 2e-20
Identities = 79/289 (27%), Positives = 128/289 (44%), Gaps = 24/289 (8%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
+ AG +AG + + P+D +K MQ K+ +I+G +++++ G RG
Sbjct: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS--KSDKMNIFGGFRQMVKEGGIRSLWRGNG 236
Query: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVK 168
++ P A+ F YE K+ L + G I+GSMA + P EV+K
Sbjct: 237 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGT--FERFISGSMAGATAQTFIYPMEVMK 294
Query: 169 QRLQMYNSQHRSAI-SCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE------- 220
RL + + S I C + + + EGLGAFY+ Y L IP+ I YE
Sbjct: 295 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
Query: 221 --FLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR 278
F ++ VNP + G L+ A+ PL + +T + Q ++ S +
Sbjct: 355 DNFAKDSVNP----GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ-----AMLEGSPQ 405
Query: 279 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
L+ M FR + G+ G ++GI + +P+ IS+ VYE K L
Sbjct: 406 LN-MVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 453
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 8/92 (8%)
Query: 238 IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAG 297
+++GG+AGA++ +T PLD K ++ + + + NI G FR + + G+
Sbjct: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-NIFG-------GFRQMVKEGGIRS 230
Query: 298 YFKGIQARVIYQMPSTAISWSVYEFFKYFLTK 329
++G VI P TA+ + YE +K LT+
Sbjct: 231 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTE 262
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 95.9 bits (237), Expect = 5e-20
Identities = 77/287 (26%), Positives = 132/287 (45%), Gaps = 29/287 (10%)
Query: 56 GILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAG 115
G+LE + P + R + DP ++T A KI+R EG G+ ++
Sbjct: 72 GVLEPLYLCPNGA---RCATWFQDP-TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTV 127
Query: 116 PAHAMYFACYENMKRTL------NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQ 169
PA A+YF Y+ +K L +D++ A +AG++A L V++P E+++
Sbjct: 128 PATAIYFTAYDQLKAFLCGRALTSDLY--------APMVAGALARLGTVTVISPLELMRT 179
Query: 170 RLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPH 229
+LQ + +R +C+RT G + + + ++PF ++++ YE ++ +N
Sbjct: 180 KLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGF 239
Query: 230 RTYNPQS---HIISGGLAGALAAAATTPLDVCKT----LLNTQENVALSLANISGRLSGM 282
R + S ++GG++G +AA T P DV KT L E V ++ ++
Sbjct: 240 RPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWL-- 297
Query: 283 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTK 329
R + +G G F G R+I PS AI S YEF K F +
Sbjct: 298 --LLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQR 342
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/55 (30%), Positives = 30/55 (54%)
Query: 278 RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQL 332
R +G +AF + + G + G+ A ++ +P+TAI ++ Y+ K FL R L
Sbjct: 95 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL 149
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
Query: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 247 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 303
Query: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 304 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 363
Query: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 364 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 416
Query: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 417 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 280 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 336
Query: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 337 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 393
Query: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 394 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 453
Query: 216 FITYEFLQ 223
++ YE L+
Sbjct: 454 YVVYENLK 461
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 280
Query: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 281 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 337
Query: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 338 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 397
Query: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 398 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 450
Query: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 451 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 314 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 370
Query: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 371 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 427
Query: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 428 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 487
Query: 216 FITYEFLQ 223
++ YE L+
Sbjct: 488 YVVYENLK 495
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 209 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 266
Query: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 267 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 323
Query: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 324 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 383
Query: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 384 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 436
Query: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 437 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 484
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 300 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 356
Query: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 357 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 413
Query: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 414 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 473
Query: 216 FITYEFLQ 223
++ YE L+
Sbjct: 474 YVVYENLK 481
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
Query: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 247 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 303
Query: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 304 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 363
Query: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 364 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 416
Query: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 417 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 280 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 336
Query: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 337 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 393
Query: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 394 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 453
Query: 216 FITYEFLQ 223
++ YE L+
Sbjct: 454 YVVYENLK 461
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 86 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 143
Query: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 144 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 200
Query: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 201 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 260
Query: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 261 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 313
Query: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 314 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 361
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 177 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 233
Query: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 234 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 290
Query: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 291 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 350
Query: 216 FITYEFLQ 223
++ YE L+
Sbjct: 351 YVVYENLK 358
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 280
Query: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 281 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 337
Query: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 338 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 397
Query: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 398 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 450
Query: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 451 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 314 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 370
Query: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 371 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 427
Query: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 428 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 487
Query: 216 FITYEFLQ 223
++ YE L+
Sbjct: 488 YVVYENLK 495
>gi|115430257 solute carrier family 25, member 26 [Homo sapiens]
Length = 274
Score = 92.0 bits (227), Expect = 7e-19
Identities = 76/263 (28%), Positives = 118/263 (44%), Gaps = 32/263 (12%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
+ AG +AG+ +++P+D++KTR+QS KA GF GV
Sbjct: 10 LVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNKA---------------GGFHGIYAGVP 54
Query: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLA---NGIAGSMATLLHDAVMNPAE 165
+G+ P A +F YE +K L H +S+L + +A S ++ + P+E
Sbjct: 55 SAAIGSFPNAAAFFITYEYVKWFL----HADSSSYLTPMKHMLAASAGEVVACLIRVPSE 110
Query: 166 VVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
VVKQR Q+ S + EG+ YR Y + + IPF + F +E L+
Sbjct: 111 VVKQRAQV--SASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKAL 168
Query: 226 VNPHRTYNPQS--HIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMA 283
+ + + S + G AG AAA TTPLDV KT + L+ A S +
Sbjct: 169 WSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKT------RIMLAKAGSSTADGNVL 222
Query: 284 NAFRTVYQLNGLAGYFKGIQARV 306
+ V++ GLAG F G+ R+
Sbjct: 223 SVLHGVWRSQGLAGLFAGVFPRM 245
Score = 33.5 bits (75), Expect = 0.28
Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 21/90 (23%)
Query: 238 IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAG 297
+++GG+AG PLD KT L + + N +G G G
Sbjct: 10 LVAGGVAGVSVDLILFPLDTIKTRLQSPQGF-----NKAG----------------GFHG 48
Query: 298 YFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
+ G+ + I P+ A + YE+ K+FL
Sbjct: 49 IYAGVPSAAIGSFPNAAAFFITYEYVKWFL 78
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 90.5 bits (223), Expect = 2e-18
Identities = 81/320 (25%), Positives = 135/320 (42%), Gaps = 32/320 (10%)
Query: 25 GGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQ-SLSPDPKAQ 83
G G+ A+GS + + ++ AG G+L + ++P+D VK R S + + +
Sbjct: 3 GQGQSASGSSAWSTVFRHVRYE-NLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPK 61
Query: 84 YTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMK--RTLNDVFHHQGN 141
Y I L I + +G +GV I GAG + +YF Y +K +T +
Sbjct: 62 YNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEAT 121
Query: 142 SHLANGIAGSMATLLHDAVMNPAEVVKQRLQMY-----NSQHRSAISCIRT---VWRTEG 193
+L + TL + NP V K RL + NS HR T +++ EG
Sbjct: 122 EYLVSAAEAGAMTL---CITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEG 178
Query: 194 LGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQS------HIISGGLAGAL 247
+ Y+ + L ++ F+ YE L+ + N H P++ +I L+
Sbjct: 179 VRGLYKGFVPGL-FGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIF 237
Query: 248 AAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVI 307
A AAT P V + L Q SG+ + ++ G+ G++KGI +I
Sbjct: 238 AVAATYPYQVVRARLQDQHMF----------YSGVIDVITKTWRKEGVGGFYKGIAPNLI 287
Query: 308 YQMPSTAISWSVYEFFKYFL 327
P+ I++ VYE +FL
Sbjct: 288 RVTPACCITFVVYENVSHFL 307
Score = 36.6 bits (83), Expect = 0.033
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 4/92 (4%)
Query: 44 SVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRP 103
S +++ A++ I + YP V+ R+Q D Y+ + + K R EG
Sbjct: 223 STVEYISVAALSKIFAVAATYPYQVVRARLQ----DQHMFYSGVIDVITKTWRKEGVGGF 278
Query: 104 LRGVNVMIMGAGPAHAMYFACYENMKRTLNDV 135
+G+ ++ PA + F YEN+ L D+
Sbjct: 279 YKGIAPNLIRVTPACCITFVVYENVSHFLLDL 310
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 89.0 bits (219), Expect = 6e-18
Identities = 82/324 (25%), Positives = 135/324 (41%), Gaps = 43/324 (13%)
Query: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLS-PDPKAQ------------------------ 83
M A IL ++ P+D VK R+Q+ + P PK +
Sbjct: 19 MLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWY 78
Query: 84 -----YTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHH 138
+ A KI+R EG G+ ++ A PA +YF CY+ + L
Sbjct: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
Query: 139 QGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFY 198
N +AG +A V++P E+++ ++Q + + +G + +
Sbjct: 139 --NETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLW 196
Query: 199 RSYTTQLTMNIPFQSIHFITYEFLQEQV-NPHRTYNPQSHI--ISGGLAGALAAAATTPL 255
R + + ++PF ++++ YE L++ + Y P I SG L+G+ AA AT P
Sbjct: 197 RGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPF 256
Query: 256 DVCKTLLNTQ----ENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMP 311
DV KT TQ E+ +S+ M N + NG +G F G+ R+I P
Sbjct: 257 DVVKTQKQTQLWTYESHKISMPLHMSTWIIMKN----IVAKNGFSGLFSGLIPRLIKIAP 312
Query: 312 STAISWSVYEFFKYFLTKRQLENR 335
+ AI S YEF K F K+ + +
Sbjct: 313 ACAIMISTYEFGKAFFQKQNVRRQ 336
>gi|157388925 solute carrier family 25, member 38 [Homo sapiens]
Length = 304
Score = 87.0 bits (214), Expect = 2e-17
Identities = 66/275 (24%), Positives = 124/275 (45%), Gaps = 19/275 (6%)
Query: 52 GAMAGILEHSVMYPVDSVKTRMQSLSP-DPKAQYTSIYGALKKIMRTEGFWRPLRGVNVM 110
G+++G + P+D +KTR+Q+L P D ++ + L K++RTE +G++
Sbjct: 34 GSISGTCSTLLFQPLDLLKTRLQTLQPSDHGSRRVGMLAVLLKVVRTESLLGLWKGMSPS 93
Query: 111 IMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQR 170
I+ P +YF ++K+ + L + + G + + M+P V+K R
Sbjct: 94 IVRCVPGVGIYFGTLYSLKQYF---LRGHPPTALESVMLGVGSRSVAGVCMSPITVIKTR 150
Query: 171 LQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPH- 229
+ + S + +R+++ +EG + T L + PF I+ + Y + + PH
Sbjct: 151 YESGKYGYESIYAALRSIYHSEGHRGLFSGLTATLLRDAPFSGIYLMFYN-QTKNIVPHD 209
Query: 230 ---RTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAF 286
T P ++ G AG LA+ T P DV KT + + + A
Sbjct: 210 QVDATLIPITNFSCGIFAGILASLVTQPADVIKTHMQLYPL----------KFQWIGQAV 259
Query: 287 RTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYE 321
+++ GL G+F+G R + + A++W+VYE
Sbjct: 260 TLIFKDYGLRGFFQGGIPRALRRTLMAAMAWTVYE 294
Score = 43.9 bits (102), Expect = 2e-04
Identities = 47/207 (22%), Positives = 86/207 (41%), Gaps = 25/207 (12%)
Query: 135 VFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM-----YNSQHRSAISCIRTVW 189
+ H + L I+G+ +TLL P +++K RLQ + S+ ++ + V
Sbjct: 23 MLHPVIKAFLCGSISGTCSTLL----FQPLDLLKTRLQTLQPSDHGSRRVGMLAVLLKVV 78
Query: 190 RTEGLGAFYRSYTTQLTMNIPFQSIHFIT-YEFLQEQVNPHRTYNPQSHIISGGLAGALA 248
RTE L ++ + + +P I+F T Y Q + H +S ++ G + ++A
Sbjct: 79 RTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESVMLGVG-SRSVA 137
Query: 249 AAATTPLDVCKTLLNTQENVALSLANISGRLS--GMANAFRTVYQLNGLAGYFKGIQARV 306
+P+ V KT SG+ + A R++Y G G F G+ A +
Sbjct: 138 GVCMSPITVIKTRYE------------SGKYGYESIYAALRSIYHSEGHRGLFSGLTATL 185
Query: 307 IYQMPSTAISWSVYEFFKYFLTKRQLE 333
+ P + I Y K + Q++
Sbjct: 186 LRDAPFSGIYLMFYNQTKNIVPHDQVD 212
Score = 28.5 bits (62), Expect = 8.9
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 47 THMTAGAMAGILEHSVMYPVDSVKTRMQ 74
T+ + G AGIL V P D +KT MQ
Sbjct: 219 TNFSCGIFAGILASLVTQPADVIKTHMQ 246
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 87.0 bits (214), Expect = 2e-17
Identities = 71/295 (24%), Positives = 134/295 (45%), Gaps = 31/295 (10%)
Query: 51 AGAMAGILEHSVMYPVDSVKTRMQ----SLS-PDPKAQYTSIYGALKKIMRTEG---FWR 102
AG+++G++ +++ P D +K R Q LS DP A+Y I A ++I++ EG FW+
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWK 80
Query: 103 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 162
++ +G G A+ F +E + ++ + + + G +A + ++
Sbjct: 81 GHVPAQILSIGYG---AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 163 PAEVVKQRL------QMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHF 216
P +V++ R ++YN+ + + T++R+EG FY+ L P+ + F
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHA----VGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 217 ITYEFLQE------QVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQ--ENV 268
Y L+ + N Q+ ++ G AG ++ T PLD+ K L E+
Sbjct: 194 SCYSSLKHLYKWAIPAEGKKNENLQN-LLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 269 ALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFF 323
+ + R G+ + + V Q G G+FKG+ ++ ST + YEFF
Sbjct: 253 RAAFGQVR-RYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFF 306
Score = 71.6 bits (174), Expect = 9e-13
Identities = 45/199 (22%), Positives = 95/199 (47%), Gaps = 20/199 (10%)
Query: 139 QGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMY---------NSQHRSAISCIRTVW 189
+ N+ +AGS++ L+ A+++P +V+K R Q+ ++++ + R +
Sbjct: 11 RNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQIL 70
Query: 190 RTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQS---HIISGGLAGA 246
+ EG AF++ + ++I + ++ F+++E L E V+ Y+ + H + GGLA
Sbjct: 71 QEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAAC 130
Query: 247 LAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARV 306
+A P+DV +T Q + + + +A T+Y+ G ++KG+ +
Sbjct: 131 MATLTVHPVDVLRTRFAAQGEPKV--------YNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
Query: 307 IYQMPSTAISWSVYEFFKY 325
I P + +S Y K+
Sbjct: 183 IAIFPYAGLQFSCYSSLKH 201
Score = 63.5 bits (153), Expect = 3e-10
Identities = 46/189 (24%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 46 STHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLR 105
S H G +A + ++PVD ++TR + +PK Y ++ A+ + R+EG +
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRF-AAQGEPKV-YNTLRHAVGTMYRSEGPQVFYK 176
Query: 106 GVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQG--NSHLANGIAGSMATLLHDAVMNP 163
G+ ++ P + F+CY ++K +G N +L N + GS A ++ + P
Sbjct: 177 GLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYP 236
Query: 164 AEVVKQRLQMYNSQHRSA-----------ISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQ 212
++ K+RLQ+ +H A + C + V + EG F++ + L
Sbjct: 237 LDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALST 296
Query: 213 SIHFITYEF 221
F +YEF
Sbjct: 297 GFMFFSYEF 305
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 87.0 bits (214), Expect = 2e-17
Identities = 71/295 (24%), Positives = 134/295 (45%), Gaps = 31/295 (10%)
Query: 51 AGAMAGILEHSVMYPVDSVKTRMQ----SLS-PDPKAQYTSIYGALKKIMRTEG---FWR 102
AG+++G++ +++ P D +K R Q LS DP A+Y I A ++I++ EG FW+
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWK 80
Query: 103 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 162
++ +G G A+ F +E + ++ + + + G +A + ++
Sbjct: 81 GHVPAQILSIGYG---AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 163 PAEVVKQRL------QMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHF 216
P +V++ R ++YN+ + + T++R+EG FY+ L P+ + F
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHA----VGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 217 ITYEFLQE------QVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQ--ENV 268
Y L+ + N Q+ ++ G AG ++ T PLD+ K L E+
Sbjct: 194 SCYSSLKHLYKWAIPAEGKKNENLQN-LLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 269 ALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFF 323
+ + R G+ + + V Q G G+FKG+ ++ ST + YEFF
Sbjct: 253 RAAFGQVR-RYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFF 306
Score = 71.6 bits (174), Expect = 9e-13
Identities = 45/199 (22%), Positives = 95/199 (47%), Gaps = 20/199 (10%)
Query: 139 QGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMY---------NSQHRSAISCIRTVW 189
+ N+ +AGS++ L+ A+++P +V+K R Q+ ++++ + R +
Sbjct: 11 RNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQIL 70
Query: 190 RTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQS---HIISGGLAGA 246
+ EG AF++ + ++I + ++ F+++E L E V+ Y+ + H + GGLA
Sbjct: 71 QEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAAC 130
Query: 247 LAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARV 306
+A P+DV +T Q + + + +A T+Y+ G ++KG+ +
Sbjct: 131 MATLTVHPVDVLRTRFAAQGEPKV--------YNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
Query: 307 IYQMPSTAISWSVYEFFKY 325
I P + +S Y K+
Sbjct: 183 IAIFPYAGLQFSCYSSLKH 201
Score = 63.5 bits (153), Expect = 3e-10
Identities = 46/189 (24%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 46 STHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLR 105
S H G +A + ++PVD ++TR + +PK Y ++ A+ + R+EG +
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRF-AAQGEPKV-YNTLRHAVGTMYRSEGPQVFYK 176
Query: 106 GVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQG--NSHLANGIAGSMATLLHDAVMNP 163
G+ ++ P + F+CY ++K +G N +L N + GS A ++ + P
Sbjct: 177 GLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYP 236
Query: 164 AEVVKQRLQMYNSQHRSA-----------ISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQ 212
++ K+RLQ+ +H A + C + V + EG F++ + L
Sbjct: 237 LDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALST 296
Query: 213 SIHFITYEF 221
F +YEF
Sbjct: 297 GFMFFSYEF 305
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 87.0 bits (214), Expect = 2e-17
Identities = 71/295 (24%), Positives = 134/295 (45%), Gaps = 31/295 (10%)
Query: 51 AGAMAGILEHSVMYPVDSVKTRMQ----SLS-PDPKAQYTSIYGALKKIMRTEG---FWR 102
AG+++G++ +++ P D +K R Q LS DP A+Y I A ++I++ EG FW+
Sbjct: 21 AGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWK 80
Query: 103 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 162
++ +G G A+ F +E + ++ + + + G +A + ++
Sbjct: 81 GHVPAQILSIGYG---AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 163 PAEVVKQRL------QMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHF 216
P +V++ R ++YN+ + + T++R+EG FY+ L P+ + F
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHA----VGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 217 ITYEFLQE------QVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQ--ENV 268
Y L+ + N Q+ ++ G AG ++ T PLD+ K L E+
Sbjct: 194 SCYSSLKHLYKWAIPAEGKKNENLQN-LLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 269 ALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFF 323
+ + R G+ + + V Q G G+FKG+ ++ ST + YEFF
Sbjct: 253 RAAFGQVR-RYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFF 306
Score = 71.6 bits (174), Expect = 9e-13
Identities = 45/199 (22%), Positives = 95/199 (47%), Gaps = 20/199 (10%)
Query: 139 QGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMY---------NSQHRSAISCIRTVW 189
+ N+ +AGS++ L+ A+++P +V+K R Q+ ++++ + R +
Sbjct: 11 RNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQIL 70
Query: 190 RTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQS---HIISGGLAGA 246
+ EG AF++ + ++I + ++ F+++E L E V+ Y+ + H + GGLA
Sbjct: 71 QEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAAC 130
Query: 247 LAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARV 306
+A P+DV +T Q + + + +A T+Y+ G ++KG+ +
Sbjct: 131 MATLTVHPVDVLRTRFAAQGEPKV--------YNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
Query: 307 IYQMPSTAISWSVYEFFKY 325
I P + +S Y K+
Sbjct: 183 IAIFPYAGLQFSCYSSLKH 201
Score = 63.5 bits (153), Expect = 3e-10
Identities = 46/189 (24%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 46 STHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLR 105
S H G +A + ++PVD ++TR + +PK Y ++ A+ + R+EG +
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRF-AAQGEPKV-YNTLRHAVGTMYRSEGPQVFYK 176
Query: 106 GVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQG--NSHLANGIAGSMATLLHDAVMNP 163
G+ ++ P + F+CY ++K +G N +L N + GS A ++ + P
Sbjct: 177 GLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYP 236
Query: 164 AEVVKQRLQMYNSQHRSA-----------ISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQ 212
++ K+RLQ+ +H A + C + V + EG F++ + L
Sbjct: 237 LDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALST 296
Query: 213 SIHFITYEF 221
F +YEF
Sbjct: 297 GFMFFSYEF 305
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 87.0 bits (214), Expect = 2e-17
Identities = 74/288 (25%), Positives = 122/288 (42%), Gaps = 29/288 (10%)
Query: 51 AGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVM 110
AG ++G L + +P D+VK R+Q+ + Y I + KI R E +G++
Sbjct: 8 AGWISGALGLVLGHPFDTVKVRLQT-----QTTYRGIVDCMVKIYRHESLLGFFKGMSFP 62
Query: 111 IMGAGPAHAMYFACYENMKRTLNDVFHH----QGNSHLANGIAGSMATLLHDAVMNPAEV 166
I +++ F Y N L H Q S++ +AG L + P ++
Sbjct: 63 IASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDL 122
Query: 167 VKQRLQMYNS----------QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHF 216
+K RLQ +++ + C +++R EG +R + P I+F
Sbjct: 123 IKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYF 182
Query: 217 ITYEFLQEQVNPHRTYNPQSH--IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLAN 274
ITYE L Q P NP S +++GG AG + A TPLD+ K+ + L
Sbjct: 183 ITYEGLCRQYTP-EGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMD---GLRRRV 238
Query: 275 ISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEF 322
G L M ++ R GL +F+G+ P A+++ YE+
Sbjct: 239 YQGMLDCMVSSIRQ----EGLGVFFRGVTINSARAFPVNAVTFLSYEY 282
Score = 68.2 bits (165), Expect = 1e-11
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 13/182 (7%)
Query: 51 AGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQ-------YTSIYGALKKIMRTEGFWRP 103
AG G L+ + P D +K R+Q+ + +P+AQ Y I R EG
Sbjct: 105 AGCTGGFLQAYCLAPFDLIKVRLQNQT-EPRAQPGSPPPRYQGPVHCAASIFREEGPRGL 163
Query: 104 LRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNP 163
RG + + P +YF YE + R Q S +AG A + P
Sbjct: 164 FRGAWALTLRDTPTVGIYFITYEGLCRQYTP--EGQNPSSATVLVAGGFAGIASWVAATP 221
Query: 164 AEVVKQRLQMYNSQHR---SAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE 220
+++K R+QM + R + C+ + R EGLG F+R T P ++ F++YE
Sbjct: 222 LDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYE 281
Query: 221 FL 222
+L
Sbjct: 282 YL 283
Score = 52.4 bits (124), Expect = 6e-07
Identities = 42/181 (23%), Positives = 75/181 (41%), Gaps = 8/181 (4%)
Query: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTM 207
+AG ++ L + +P + VK RLQ + +R + C+ ++R E L F++ + +
Sbjct: 7 VAGWISGALGLVLGHPFDTVKVRLQTQTT-YRGIVDCMVKIYRHESLLGFFKGMSFPIAS 65
Query: 208 NIPFQSIHFITYE----FLQEQVNPHRTYNPQSHI---ISGGLAGALAAAATTPLDVCKT 260
S+ F Y L + R P S++ ++G G L A P D+ K
Sbjct: 66 IAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKV 125
Query: 261 LLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVY 320
L Q + R G + ++++ G G F+G A + P+ I + Y
Sbjct: 126 RLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITY 185
Query: 321 E 321
E
Sbjct: 186 E 186
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 40 PTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEG 99
P+SA+V + AG AGI P+D +K+RMQ + + Y + + +R EG
Sbjct: 199 PSSATV---LVAGGFAGIASWVAATPLDMIKSRMQ-MDGLRRRVYQGMLDCMVSSIRQEG 254
Query: 100 FWRPLRGVNVMIMGAGPAHAMYFACYENMKR 130
RGV + A P +A+ F YE + R
Sbjct: 255 LGVFFRGVTINSARAFPVNAVTFLSYEYLLR 285
Score = 33.1 bits (74), Expect = 0.36
Identities = 23/102 (22%), Positives = 38/102 (37%), Gaps = 11/102 (10%)
Query: 234 PQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLN 293
P ++G ++GAL P D K L TQ G+ + +Y+
Sbjct: 2 PVEEFVAGWISGALGLVLGHPFDTVKVRLQTQTT-----------YRGIVDCMVKIYRHE 50
Query: 294 GLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENR 335
L G+FKG+ + ++ + VY LT + R
Sbjct: 51 SLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQER 92
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 86.7 bits (213), Expect = 3e-17
Identities = 70/299 (23%), Positives = 127/299 (42%), Gaps = 20/299 (6%)
Query: 40 PTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQ---YTSIYGALKKIMR 96
P S ++ AG G+ V +P+D+VK R+Q+ P Q Y+ + +K +
Sbjct: 5 PKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLF 64
Query: 97 TEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLL 156
EG RG+ I+G P A+ F + + + L S+ AG ++ +
Sbjct: 65 REGITGLYRGMAAPIIGVTPMFAVCFFGF-GLGKKLQQKHPEDVLSYPQLFAAGMLSGVF 123
Query: 157 HDAVMNPAEVVKQRLQMY----NSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQ 212
+M P E +K LQ+ S++ + C + +++ G+ Y+ L ++P
Sbjct: 124 TTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPAS 183
Query: 213 SIHFITYEFLQEQVNPH----RTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENV 268
++F+TYE+L+ P + +++GG+AG A P DV K+ T
Sbjct: 184 GMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQT---- 239
Query: 269 ALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
A +G + R + + G+ +KG A +I P+ A + +E FL
Sbjct: 240 ----APPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294
Score = 60.1 bits (144), Expect = 3e-09
Identities = 47/187 (25%), Positives = 87/187 (46%), Gaps = 17/187 (9%)
Query: 51 AGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVM 110
AG ++G+ +M P + +K +Q + +++YT KK+ + G +G +
Sbjct: 116 AGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLT 175
Query: 111 IMGAGPAHAMYFACYENMKRTLNDVFHHQGN--SHLANG---IAGSMATLLHDAVMNPAE 165
+M PA MYF YE +K ++F +G S L+ +AG +A + + AV P +
Sbjct: 176 LMRDVPASGMYFMTYEWLK----NIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPD 231
Query: 166 VVKQRLQ-----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE 220
V+K R Q Y + R +R + R EG+ + Y+ + + P + F+ +E
Sbjct: 232 VLKSRFQTAPPGKYPNGFRDV---LRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFE 288
Query: 221 FLQEQVN 227
+ +N
Sbjct: 289 VAMKFLN 295
Score = 51.6 bits (122), Expect = 1e-06
Identities = 49/208 (23%), Positives = 82/208 (39%), Gaps = 18/208 (8%)
Query: 142 SHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQ-------HRSAISCIRTVWRTEGL 194
S L N +AG + V +P + VK RLQ + C R EG+
Sbjct: 9 SPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGI 68
Query: 195 GAFYRSYTTQLTMNIPFQSIHFITYEFLQ--EQVNPHRTYNPQSHIISGGLAGALAAAAT 252
YR + P ++ F + + +Q +P + +G L+G
Sbjct: 69 TGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIM 128
Query: 253 TPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPS 312
TP + K LL Q + S + +G + + +YQ G+ G +KG ++ +P+
Sbjct: 129 TPGERIKCLLQIQASSGES------KYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPA 182
Query: 313 TAISWSVYEFFKYFLT---KRQLENRAP 337
+ + + YE+ K T KR E AP
Sbjct: 183 SGMYFMTYEWLKNIFTPEGKRVSELSAP 210
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 85.5 bits (210), Expect = 6e-17
Identities = 81/303 (26%), Positives = 126/303 (41%), Gaps = 33/303 (10%)
Query: 44 SVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRP 103
S++ + G +AG++ + ++P+D KTR+Q+ KA Y + L K R EGF+
Sbjct: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQN--QHGKAMYKGMIDCLMKTARAEGFFGM 64
Query: 104 LRGVNVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMN 162
RG V + P A+ A + +R L D + G M ++ M
Sbjct: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPME 124
Query: 163 PAEVVKQ---RLQMYNSQHRSAISCIRT-----------------VW---RTEGLGAFYR 199
++ Q RL +++ SA S R+ W RT+GL YR
Sbjct: 125 MLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYR 184
Query: 200 SYTTQLTMNIPFQSIHFITYEFLQEQ-VNPHRTYNPQSH-IISGGLAGALAAAATTPLDV 257
L +IPF I+F + L N +H +SG +AG++AA A TPLDV
Sbjct: 185 GLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDV 244
Query: 258 CKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISW 317
KT + T L SG+ + R ++ G + + KG R + P I+
Sbjct: 245 LKTRIQT-----LKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQ 299
Query: 318 SVY 320
VY
Sbjct: 300 GVY 302
Score = 50.4 bits (119), Expect = 2e-06
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 19/202 (9%)
Query: 138 HQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYN--SQHRSAISCIRTVWRTEGLG 195
HQ S A I G +A L+ + P ++ K RLQ + + ++ I C+ R EG
Sbjct: 3 HQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFF 62
Query: 196 AFYRSYTTQLTMNIPFQSIHFITYEFLQE-QVNPHRTYNPQSHIISGGLAGALAAAATTP 254
YR LT+ P ++I +F + + N + +++G AG T P
Sbjct: 63 GMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCP 122
Query: 255 LDVCKTLLNTQENVAL-------SLANISGRLSGMANAFR---------TVYQLNGLAGY 298
+++ K L +A+ + + +G A+ R + + GLAG
Sbjct: 123 MEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGL 182
Query: 299 FKGIQARVIYQMPSTAISWSVY 320
++G+ A ++ +P + I + ++
Sbjct: 183 YRGLGATLLRDIPFSIIYFPLF 204
Score = 42.7 bits (99), Expect = 5e-04
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 8/99 (8%)
Query: 229 HRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRT 288
H+ + + +I+GG+AG + P+D+ KT L Q A+ GM +
Sbjct: 3 HQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAM--------YKGMIDCLMK 54
Query: 289 VYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
+ G G ++G + P AI + +FF+ L
Sbjct: 55 TARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLL 93
Score = 31.2 bits (69), Expect = 1.4
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
Query: 36 YENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPD-PKAQYTSIYGALKKI 94
+ L AS + +G +AG + + P+D +KTR+Q+L + Y+ I +K+
Sbjct: 212 FNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKL 271
Query: 95 MRTEGFWRPLRGVNVMIMGAGP----AHAMYF 122
EG ++G + P A +YF
Sbjct: 272 WIQEGPSAFMKGAGCRALVIAPLFGIAQGVYF 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.131 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,785,464
Number of Sequences: 37866
Number of extensions: 465785
Number of successful extensions: 1837
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1243
Number of HSP's gapped (non-prelim): 217
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.