Guide to the Human Genome
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Search of human proteins with 7706543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706543 HIG1 hypoxia inducible domain family, member 1B
[Homo sapiens]
         (99 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo...   203   3e-53
gi|157817101 HIG1 domain family, member 1C [Homo sapiens]              90   3e-19
gi|153085470 HIG1 domain family, member 1A isoform b [Homo sapiens]    89   7e-19
gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]    89   7e-19
gi|153085463 HIG1 domain family, member 1A isoform b [Homo sapiens]    89   7e-19
gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A...    85   1e-17
gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A...    85   1e-17
gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo ...    85   1e-17
gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Hom...    55   1e-08
gi|148727255 microtubule associated serine/threonine kinase fami...    28   1.6  
gi|10257429 immunity-related GTPase family, cinema [Homo sapiens]      28   2.0  
gi|119943143 olfactory receptor, family 1, subfamily D, member 4...    27   2.7  
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...    27   3.5  
gi|7657423 olfactory receptor, family 1, subfamily D, member 5 [...    26   7.8  

>gi|7706543 HIG1 hypoxia inducible domain family, member 1B [Homo
          sapiens]
          Length = 99

 Score =  203 bits (516), Expect = 3e-53
 Identities = 99/99 (100%), Positives = 99/99 (100%)

Query: 1  MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIH 60
          MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIH
Sbjct: 1  MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIH 60

Query: 61 LIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDAGEK 99
          LIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDAGEK
Sbjct: 61 LIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDAGEK 99


>gi|157817101 HIG1 domain family, member 1C [Homo sapiens]
          Length = 97

 Score = 90.1 bits (222), Expect = 3e-19
 Identities = 42/90 (46%), Positives = 63/90 (70%), Gaps = 2/90 (2%)

Query: 1  MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIH 60
          MS++ +W    D+++    +L+RK+R+SP VPIG+ G + V +  +Y+L+ R   KMSIH
Sbjct: 1  MSSDNQW--SADEDEGQLSRLIRKSRDSPFVPIGIAGFVTVVSCGLYKLKYRRDQKMSIH 58

Query: 61 LIHTRVAAQACAVGAIMLGAVYTMYSDYVK 90
          LIH RVAAQ   VGA+ LG +Y+MY DY++
Sbjct: 59 LIHMRVAAQGFVVGAVTLGVLYSMYKDYIR 88


>gi|153085470 HIG1 domain family, member 1A isoform b [Homo
          sapiens]
          Length = 93

 Score = 89.0 bits (219), Expect = 7e-19
 Identities = 40/78 (51%), Positives = 56/78 (71%)

Query: 11 PDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQA 70
          P  E+    KL+RK +E+P VP+G+ G   + AY +Y+L+SRG+TKMSIHLIH RVAAQ 
Sbjct: 10 PSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQG 69

Query: 71 CAVGAIMLGAVYTMYSDY 88
            VGA+ +G  Y+MY ++
Sbjct: 70 FVVGAMTVGMGYSMYREF 87


>gi|153085461 HIG1 domain family, member 1A isoform a [Homo sapiens]
          Length = 107

 Score = 89.0 bits (219), Expect = 7e-19
 Identities = 40/78 (51%), Positives = 56/78 (71%)

Query: 11  PDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQA 70
           P  E+    KL+RK +E+P VP+G+ G   + AY +Y+L+SRG+TKMSIHLIH RVAAQ 
Sbjct: 24  PSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQG 83

Query: 71  CAVGAIMLGAVYTMYSDY 88
             VGA+ +G  Y+MY ++
Sbjct: 84  FVVGAMTVGMGYSMYREF 101


>gi|153085463 HIG1 domain family, member 1A isoform b [Homo
          sapiens]
          Length = 93

 Score = 89.0 bits (219), Expect = 7e-19
 Identities = 40/78 (51%), Positives = 56/78 (71%)

Query: 11 PDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQA 70
          P  E+    KL+RK +E+P VP+G+ G   + AY +Y+L+SRG+TKMSIHLIH RVAAQ 
Sbjct: 10 PSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQG 69

Query: 71 CAVGAIMLGAVYTMYSDY 88
            VGA+ +G  Y+MY ++
Sbjct: 70 FVVGAMTVGMGYSMYREF 87


>gi|239755597 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score = 84.7 bits (208), Expect = 1e-17
 Identities = 36/75 (48%), Positives = 55/75 (73%)

Query: 14  EDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQACAV 73
           ++    KL+RK +E+PLVP+G+ G   +  Y +Y+L+SRG+T+MS+HLIH RVAAQ   V
Sbjct: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103

Query: 74  GAIMLGAVYTMYSDY 88
           GA+ +G  Y+MY ++
Sbjct: 104 GAMTIGMGYSMYREF 118


>gi|239750094 PREDICTED: similar to HIG1 domain family, member 1A
           [Homo sapiens]
          Length = 124

 Score = 84.7 bits (208), Expect = 1e-17
 Identities = 36/75 (48%), Positives = 55/75 (73%)

Query: 14  EDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQACAV 73
           ++    KL+RK +E+PLVP+G+ G   +  Y +Y+L+SRG+T+MS+HLIH RVAAQ   V
Sbjct: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103

Query: 74  GAIMLGAVYTMYSDY 88
           GA+ +G  Y+MY ++
Sbjct: 104 GAMTIGMGYSMYREF 118


>gi|239744403 PREDICTED: hypothetical protein XP_002343136 [Homo
           sapiens]
          Length = 124

 Score = 84.7 bits (208), Expect = 1e-17
 Identities = 36/75 (48%), Positives = 55/75 (73%)

Query: 14  EDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQACAV 73
           ++    KL+RK +E+PLVP+G+ G   +  Y +Y+L+SRG+T+MS+HLIH RVAAQ   V
Sbjct: 44  DEAQGSKLIRKAKETPLVPVGIAGFAALVTYGLYKLKSRGNTQMSLHLIHMRVAAQGFVV 103

Query: 74  GAIMLGAVYTMYSDY 88
           GA+ +G  Y+MY ++
Sbjct: 104 GAMTIGMGYSMYREF 118


>gi|20270389 HIG1 hypoxia inducible domain family, member 2A [Homo
           sapiens]
          Length = 106

 Score = 55.1 bits (131), Expect = 1e-08
 Identities = 33/67 (49%), Positives = 43/67 (64%), Gaps = 5/67 (7%)

Query: 19  EKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRS--RGSTKMSIHLIHTRVAAQACAVGAI 76
           EK +RKTRE+P+VPI   GCL  AA   Y L S  RG+++ S  ++ TR+AAQ   V AI
Sbjct: 37  EKFVRKTRENPVVPI---GCLATAAALTYGLYSFHRGNSQRSQLMMRTRIAAQGFTVAAI 93

Query: 77  MLGAVYT 83
           +LG   T
Sbjct: 94  LLGLAVT 100


>gi|148727255 microtubule associated serine/threonine kinase family
           member 4 isoform a [Homo sapiens]
          Length = 2434

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 10  PPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYR 48
           PPD +D ++  L    R++PL  +G GG   V  +R +R
Sbjct: 621 PPDAQDLITLLL----RQNPLERLGTGGAYEVKQHRFFR 655


>gi|10257429 immunity-related GTPase family, cinema [Homo sapiens]
          Length = 463

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 16/52 (30%), Positives = 23/52 (44%)

Query: 45  RIYRLRSRGSTKMSIHLIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDA 96
           R+Y   S G+ +++               G I  GAVYTM    +  MA+DA
Sbjct: 345 RLYSQSSDGAMRVARAFERGIPVFGTLVAGGISFGAVYTMLQGCLNEMAEDA 396


>gi|119943143 olfactory receptor, family 1, subfamily D, member 4
           [Homo sapiens]
          Length = 330

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 12/35 (34%), Positives = 19/35 (54%)

Query: 60  HLIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQ 94
           H+IHT + A  C +   +LG + T Y   V+ + Q
Sbjct: 211 HIIHTALIATGCFIFLTLLGFMTTSYVRIVRTILQ 245


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 17/65 (26%), Positives = 34/65 (52%), Gaps = 10/65 (15%)

Query: 10  PPDDEDCVSEKLLRKTRESP-----LVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHT 64
           PPDD D V +  L  T  +      ++P  L  CL+V  Y +++ + +G+ +   H+++ 
Sbjct: 545 PPDDVDIVIK--LDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPR---HILYC 599

Query: 65  RVAAQ 69
           + + Q
Sbjct: 600 KRSMQ 604


>gi|7657423 olfactory receptor, family 1, subfamily D, member 5
           [Homo sapiens]
          Length = 312

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/35 (34%), Positives = 18/35 (51%)

Query: 60  HLIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQ 94
           H+IHT + A  C +    LG + T Y   V+ + Q
Sbjct: 193 HIIHTALIATGCFIFLTPLGFMTTSYVRIVRTILQ 227


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.134    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,613,400
Number of Sequences: 37866
Number of extensions: 123239
Number of successful extensions: 358
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 345
Number of HSP's gapped (non-prelim): 14
length of query: 99
length of database: 18,247,518
effective HSP length: 70
effective length of query: 29
effective length of database: 15,596,898
effective search space: 452310042
effective search space used: 452310042
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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