Guide to the Human Genome
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Search of human proteins with 7706337

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706337 coatomer protein complex, subunit zeta 1 [Homo
sapiens]
         (177 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706337 coatomer protein complex, subunit zeta 1 [Homo sapiens]    344   3e-95
gi|7705983 coatomer protein complex, subunit zeta 2 [Homo sapiens]    263   5e-71
gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [H...    49   2e-06
gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [...    47   9e-06
gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [H...    47   9e-06
gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H...    35   0.044
gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H...    35   0.044
gi|62865871 coiled-coil domain containing 132 isoform a [Homo sa...    31   0.49 
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...    30   1.4  
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...    30   1.4  
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]            28   3.2  
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   28   3.2  
gi|188219762 denticleless homolog [Homo sapiens]                       28   4.2  
gi|148612831 kinesin family member 18A [Homo sapiens]                  27   9.3  

>gi|7706337 coatomer protein complex, subunit zeta 1 [Homo sapiens]
          Length = 177

 Score =  344 bits (882), Expect = 3e-95
 Identities = 177/177 (100%), Positives = 177/177 (100%)

Query: 1   MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA 60
           MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA
Sbjct: 1   MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIA 60

Query: 61  LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG 120
           LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG
Sbjct: 61  LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG 120

Query: 121 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR 177
           LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
Sbjct: 121 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR 177


>gi|7705983 coatomer protein complex, subunit zeta 2 [Homo sapiens]
          Length = 210

 Score =  263 bits (673), Expect = 5e-71
 Identities = 128/171 (74%), Positives = 150/171 (87%)

Query: 7   EPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLT 66
           EPSLYT+KA+ ILDNDG RL AKYYDDT+PS+KEQ  FEKN+FNKT RT+SEIA   G+T
Sbjct: 40  EPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMT 99

Query: 67  VVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVD 126
           +VYK+SIDL+ YV+GSSYENELMLM+VL CLF+SL+ MLRKNVEKR LLENM+G FL +D
Sbjct: 100 IVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLD 159

Query: 127 EIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR 177
           EIVDGGVILESDPQQV+ +V  R +D  LTEQ+V+QVLQSAKEQIKWSLL+
Sbjct: 160 EIVDGGVILESDPQQVIQKVNFRADDGGLTEQSVAQVLQSAKEQIKWSLLK 210


>gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [Homo
           sapiens]
          Length = 193

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 33/142 (23%), Positives = 71/142 (50%), Gaps = 10/142 (7%)

Query: 13  VKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEG-------- 64
           ++AIL+ +N G     ++Y   +P   +Q+   +       R D+    LEG        
Sbjct: 2   IQAILVFNNHGKPRLVRFYQ-RFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60

Query: 65  LTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLA 124
             ++Y+    LYF     S E+EL ++ ++    ++L +   +NV +  L+ +M+ +   
Sbjct: 61  YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCF-ENVCELDLIFHMDKVHYI 119

Query: 125 VDEIVDGGVILESDPQQVVHRV 146
           + E+V GG++LE++  ++V ++
Sbjct: 120 LQEVVMGGMVLETNMNEIVAQI 141


>gi|88703051 adaptor-related protein complex 1, sigma 3 subunit
           [Homo sapiens]
          Length = 154

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 12/153 (7%)

Query: 16  ILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNI----FNKTHRTDSEIALLEGLTVVYKS 71
           IL+    G     K+Y  T P  KE+K   + I     ++ HRT S +   E L +VYK 
Sbjct: 5   ILLFSRQGKLRLQKWYI-TLPD-KERKKITREIVQIILSRGHRTSSFVDWKE-LKLVYKR 61

Query: 72  SIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDG 131
              LYF     + +NEL+ + +++   + L +    NV +  ++ N E  +  +DE + G
Sbjct: 62  YASLYFCCAIENQDNELLTLEIVHRYVELLDKYF-GNVCELDIIFNFEKAYFILDEFIIG 120

Query: 132 GVILESDPQQVVHRVALRGEDVPLTEQTVSQVL 164
           G I E+  +  V  +    ED  + ++T+ + +
Sbjct: 121 GEIQETSKKIAVKAI----EDSDMLQETMEEYM 149


>gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [Homo
           sapiens]
          Length = 193

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 34/142 (23%), Positives = 72/142 (50%), Gaps = 10/142 (7%)

Query: 13  VKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEG-------- 64
           +KAILI +N G    +K+Y   Y    +Q+   +     + R ++    LEG        
Sbjct: 2   IKAILIFNNHGKPRLSKFY-QPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSD 60

Query: 65  LTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLA 124
             ++Y+    LYF     S E+EL ++ ++    ++L +   +NV +  L+ +++ +   
Sbjct: 61  NKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCF-ENVCELDLIFHVDKVHNI 119

Query: 125 VDEIVDGGVILESDPQQVVHRV 146
           + E+V GG++LE++  ++V ++
Sbjct: 120 LAEMVMGGMVLETNMNEIVTQI 141


>gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo
           sapiens]
          Length = 158

 Score = 34.7 bits (78), Expect = 0.044
 Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 6/137 (4%)

Query: 13  VKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKT-HRTDSEIALLE--GLTVVY 69
           ++ +L+    G     K+Y  T  S KE+K   + +      R     + LE   L VVY
Sbjct: 2   MRFMLLFSRQGKLRLQKWYLAT--SDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVY 59

Query: 70  KSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIV 129
           K    LYF       +NEL+ + +++   + L +    +V +  ++ N E  +  +DE +
Sbjct: 60  KRYASLYFCCAIEGQDNELITLELIHRYVELLDKYF-GSVCELDIIFNFEKAYFILDEFL 118

Query: 130 DGGVILESDPQQVVHRV 146
            GG + ++  + V+  +
Sbjct: 119 MGGDVQDTSKKSVLKAI 135


>gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo
           sapiens]
          Length = 157

 Score = 34.7 bits (78), Expect = 0.044
 Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 6/134 (4%)

Query: 16  ILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKT-HRTDSEIALLE--GLTVVYKSS 72
           +L+    G     K+Y     S KE+K   + +      R     + LE   L +VYK  
Sbjct: 4   MLLFSRQGKLRLQKWYVPL--SDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRY 61

Query: 73  IDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGG 132
             LYF       +NEL+ + +++   + L +    +V +  ++ N E  +  +DE + GG
Sbjct: 62  ASLYFCCAIEDQDNELITLEIIHRYVELLDKYF-GSVCELDIIFNFEKAYFILDEFLLGG 120

Query: 133 VILESDPQQVVHRV 146
            + E+  + V+  +
Sbjct: 121 EVQETSKKNVLKAI 134


>gi|62865871 coiled-coil domain containing 132 isoform a [Homo
           sapiens]
          Length = 964

 Score = 31.2 bits (69), Expect = 0.49
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 14/99 (14%)

Query: 30  YYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELM 89
           + D   P+VK  K F +  +++T  T SE+               +Y+ V G + + E M
Sbjct: 749 HLDAVMPAVK--KPFLQQFYSQTVSTASELRK------------PIYWIVAGKALDYEQM 794

Query: 90  LMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEI 128
           L+ + N  +D    M + N+   ALL+  E     ++E+
Sbjct: 795 LLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEV 833


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score = 29.6 bits (65), Expect = 1.4
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 97  LFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLT 156
           L  SLSQ L +N E R+ L  +    +  D++V   +I   D       V+L     PL+
Sbjct: 427 LRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSL-----PLS 481

Query: 157 EQTVSQVLQSAKEQI 171
           +Q  ++   S  E +
Sbjct: 482 QQVANESRLSMSESV 496


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 29.6 bits (65), Expect = 1.4
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 97  LFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLT 156
           L  SLSQ L +N E R+ L  +    +  D++V   +I   D       V+L     PL+
Sbjct: 423 LRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSL-----PLS 477

Query: 157 EQTVSQVLQSAKEQI 171
           +Q  ++   S  E +
Sbjct: 478 QQVANESRLSMSESV 492


>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
          Length = 4588

 Score = 28.5 bits (62), Expect = 3.2
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 7/82 (8%)

Query: 11   YTVKAILILDN------DGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEG 64
            Y + +I  +DN         RL  ++     PS+ E  +FE++ F  T      +A + G
Sbjct: 1320 YDILSIKAVDNGRPQKSSTTRLHIEWISKPKPSL-EPISFEESFFTFTVMESDPVAHMIG 1378

Query: 65   LTVVYKSSIDLYFYVIGSSYEN 86
            +  V    I L+F + G +Y++
Sbjct: 1379 VISVEPPGIPLWFDITGGNYDS 1400


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 28.5 bits (62), Expect = 3.2
 Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 16/127 (12%)

Query: 40  EQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVI------GSSYENELMLMAV 93
           E++  E+N+ N     + E   L+    +YKS +++    +       ++ + +L +MAV
Sbjct: 387 EEEILERNLTN----CEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAV 442

Query: 94  LNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDV 153
            N      S+++ +  E R  +  +E      DEI+     L ++ +++  RVA + E +
Sbjct: 443 KN------SEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERL 496

Query: 154 PLTEQTV 160
            L +Q +
Sbjct: 497 DLCQQEI 503


>gi|188219762 denticleless homolog [Homo sapiens]
          Length = 730

 Score = 28.1 bits (61), Expect = 4.2
 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 16/74 (21%)

Query: 17  LILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEG---LTVVYKSSI 73
           LILD+ G  LFA   DD              +FN T    S +A+  G    T   KSS+
Sbjct: 277 LILDSTGSTLFANCTDDNI-----------YMFNMTGLKTSPVAIFNGHQNSTFYVKSSL 325

Query: 74  --DLYFYVIGSSYE 85
             D  F V GSS E
Sbjct: 326 SPDDQFLVSGSSDE 339


>gi|148612831 kinesin family member 18A [Homo sapiens]
          Length = 898

 Score = 26.9 bits (58), Expect = 9.3
 Identities = 27/114 (23%), Positives = 50/114 (43%), Gaps = 24/114 (21%)

Query: 30  YYDDTYPSVKE-------QKAFEKNIFN-KTHRTD---------SEIALLEGLTVVYK-- 70
           +YDDTY ++K        + + + N+ N   H T          +EI LL+     Y+  
Sbjct: 338 FYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQ 397

Query: 71  ----SSIDLYFYVIGSSYENEL-MLMAVLNCLFDSLSQMLRKNVEKRALLENME 119
               +  D    +I +  E E+     +LNCLF +  ++ ++ ++   LL+  E
Sbjct: 398 KAFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENE 451


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,487,543
Number of Sequences: 37866
Number of extensions: 199999
Number of successful extensions: 478
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 469
Number of HSP's gapped (non-prelim): 14
length of query: 177
length of database: 18,247,518
effective HSP length: 95
effective length of query: 82
effective length of database: 14,650,248
effective search space: 1201320336
effective search space used: 1201320336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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