Guide to the Human Genome
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Search of human proteins with 7705558

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705558 inositol-3-phosphate synthase 1 [Homo sapiens]
         (558 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705558 inositol-3-phosphate synthase 1 [Homo sapiens]            1123   0.0  
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]              35   0.24 
gi|169211554 PREDICTED: hypothetical protein [Homo sapiens]            33   0.53 
gi|169211959 PREDICTED: hypothetical protein [Homo sapiens]            33   0.53 
gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]                  32   1.2  
gi|5031767 heat shock transcription factor 1 [Homo sapiens]            32   1.5  
gi|188595687 gamma filamin isoform b [Homo sapiens]                    32   1.5  
gi|116805322 gamma filamin isoform a [Homo sapiens]                    32   1.5  
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]          32   1.5  
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]          32   1.5  
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]          32   1.5  
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]          32   1.5  
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]          32   1.5  
gi|239047271 autophagy related 2A [Homo sapiens]                       31   3.4  
gi|169164061 PREDICTED: similar to anaphase promoting complex su...    30   4.5  
gi|239741648 PREDICTED: similar to anaphase promoting complex su...    30   4.5  
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s...    30   5.8  
gi|46487911 zinc finger protein 406 isoform ZFAT-1 [Homo sapiens]      30   7.6  
gi|93102377 RRN3 RNA polymerase I transcription factor homolog [...    30   7.6  
gi|4503313 diacylglycerol kinase epsilon [Homo sapiens]                29   10.0 

>gi|7705558 inositol-3-phosphate synthase 1 [Homo sapiens]
          Length = 558

 Score = 1123 bits (2904), Expect = 0.0
 Identities = 558/558 (100%), Positives = 558/558 (100%)

Query: 1   MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG 60
           MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG
Sbjct: 1   MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG 60

Query: 61  VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF 120
           VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF
Sbjct: 61  VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF 120

Query: 121 VPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYI 180
           VPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYI
Sbjct: 121 VPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYI 180

Query: 181 PEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPG 240
           PEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPG
Sbjct: 181 PEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPG 240

Query: 241 LNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVG 300
           LNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVG
Sbjct: 241 LNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVG 300

Query: 301 GDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVV 360
           GDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVV
Sbjct: 301 GDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVV 360

Query: 361 DDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDS 420
           DDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDS
Sbjct: 361 DDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDS 420

Query: 421 LLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALF 480
           LLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALF
Sbjct: 421 LLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALF 480

Query: 481 RQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNG 540
           RQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNG
Sbjct: 481 RQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNG 540

Query: 541 CTGDANGHLQEEPPMPTT 558
           CTGDANGHLQEEPPMPTT
Sbjct: 541 CTGDANGHLQEEPPMPTT 558


>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
          Length = 1543

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 328  SIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVVDDMVQSNPVLYTPGEE 376
            S++S  HLG    +  S   Q +SK+++K+N   D  +S P L+  G+E
Sbjct: 1370 SLISSPHLGREKKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDE 1418


>gi|169211554 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 115

 Score = 33.5 bits (75), Expect = 0.53
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 472 GSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPV-AATYPMLNK 530
           G+ +    + Q+S + +++    GLP  + + +      P P  K + P+ AAT    ++
Sbjct: 12  GNALQKRCWYQKSAVFSVISRAEGLPAPHTVSVTGAACSPDPFRKELPPLSAATDTAPSR 71

Query: 531 KGPVPAATNGCTGDANGHLQEEPPMP 556
             P P+ T G  G AN    +EPP+P
Sbjct: 72  AAPCPS-TPGAAGRAN---NKEPPLP 93


>gi|169211959 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 115

 Score = 33.5 bits (75), Expect = 0.53
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 472 GSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPV-AATYPMLNK 530
           G+ +    + Q+S + +++    GLP  + + +      P P  K + P+ AAT    ++
Sbjct: 12  GNALQKRCWYQKSAVFSVISRAEGLPAPHTVSVTGAACSPDPFRKELPPLSAATDTAPSR 71

Query: 531 KGPVPAATNGCTGDANGHLQEEPPMP 556
             P P+ T G  G AN    +EPP+P
Sbjct: 72  AAPCPS-TPGAAGRAN---NKEPPLP 93


>gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]
          Length = 352

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 24/90 (26%), Positives = 37/90 (41%)

Query: 304 FKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVVDDM 363
           F+    K K +  D L+G+  +T        L + D EN   P  FR K  +  +     
Sbjct: 5   FRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPF 64

Query: 364 VQSNPVLYTPGEEPDHCVVIKYVPYVGDSK 393
            + + + Y   E  +H     YVPY G+ K
Sbjct: 65  DREHLLSYLEKEALEHKDREDYVPYTGEKK 94


>gi|5031767 heat shock transcription factor 1 [Homo sapiens]
          Length = 529

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 3/62 (4%)

Query: 497 PPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEE--PP 554
           PPQ+  + E    RP      + P A    +L +  P PA+    T DA GH   E  PP
Sbjct: 304 PPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALT-DARGHTDTEGRPP 362

Query: 555 MP 556
            P
Sbjct: 363 SP 364


>gi|188595687 gamma filamin isoform b [Homo sapiens]
          Length = 2692

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 299  VGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSN 358
            VGGD F +       V  DFL    L +   ++    G    ++++A +   S +V  + 
Sbjct: 2180 VGGDPFPA-------VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAE 2232

Query: 359  VVDDMVQSNPVLYTPGEEPDHCVVIKY 385
            +V+    +  V + P E   H V +KY
Sbjct: 2233 IVEGEDSAYSVRFVPQEMGPHTVAVKY 2259


>gi|116805322 gamma filamin isoform a [Homo sapiens]
          Length = 2725

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 299  VGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSN 358
            VGGD F +       V  DFL    L +   ++    G    ++++A +   S +V  + 
Sbjct: 2213 VGGDPFPA-------VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAE 2265

Query: 359  VVDDMVQSNPVLYTPGEEPDHCVVIKY 385
            +V+    +  V + P E   H V +KY
Sbjct: 2266 IVEGEDSAYSVRFVPQEMGPHTVAVKY 2292


>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
          Length = 1062

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 6/49 (12%)

Query: 511 PGP---SLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMP 556
           PGP   S    GP AA  P L   GPV AA +G    A G L  +PP P
Sbjct: 39  PGPLATSAAPPGPPAAASPCL---GPVAAAGSGLRRGAEGILAPQPPPP 84


>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
          Length = 1044

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 6/49 (12%)

Query: 511 PGP---SLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMP 556
           PGP   S    GP AA  P L   GPV AA +G    A G L  +PP P
Sbjct: 39  PGPLATSAAPPGPPAAASPCL---GPVAAAGSGLRRGAEGILAPQPPPP 84


>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
          Length = 1097

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 6/49 (12%)

Query: 511 PGP---SLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMP 556
           PGP   S    GP AA  P L   GPV AA +G    A G L  +PP P
Sbjct: 39  PGPLATSAAPPGPPAAASPCL---GPVAAAGSGLRRGAEGILAPQPPPP 84


>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
          Length = 1075

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 6/49 (12%)

Query: 511 PGP---SLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMP 556
           PGP   S    GP AA  P L   GPV AA +G    A G L  +PP P
Sbjct: 39  PGPLATSAAPPGPPAAASPCL---GPVAAAGSGLRRGAEGILAPQPPPP 84


>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
          Length = 1044

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/49 (44%), Positives = 24/49 (48%), Gaps = 6/49 (12%)

Query: 511 PGP---SLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMP 556
           PGP   S    GP AA  P L   GPV AA +G    A G L  +PP P
Sbjct: 39  PGPLATSAAPPGPPAAASPCL---GPVAAAGSGLRRGAEGILAPQPPPP 84


>gi|239047271 autophagy related 2A [Homo sapiens]
          Length = 1938

 Score = 30.8 bits (68), Expect = 3.4
 Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 19/147 (12%)

Query: 408  TNTLVLHNTCEDSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAP 467
            +N +V  ++C DS          ALL  L Q V    D+ P P+   P       L ++P
Sbjct: 1214 SNNVVHVHSCADSC---------ALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKLSESP 1264

Query: 468  L-VPPGSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAA-TY 525
              +P   PV  AL  QR   + +L             L    +  G  L +  P++   +
Sbjct: 1265 ASLPSCPPVETALINQRDLADALL--------DTERSLRELAQPSGGHLPQASPISVYLF 1316

Query: 526  PMLNKKGPVPAATNGCTGDANGHLQEE 552
            P      P P+   G    + G   EE
Sbjct: 1317 PGERSGAPPPSPPVGGPAGSLGSCSEE 1343


>gi|169164061 PREDICTED: similar to anaphase promoting complex
          subunit 1 [Homo sapiens]
          Length = 275

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 17/45 (37%), Positives = 22/45 (48%)

Query: 30 TRVSREGGVLKVHPTSTRFTFRTARQVPRLGVMLVGWGGNNGSTL 74
          TR++     L+      RF+FR +  V  L   LVGW  N G TL
Sbjct: 52 TRITVAPQKLQAEQEENRFSFRHSTSVSSLAERLVGWMTNVGFTL 96


>gi|239741648 PREDICTED: similar to anaphase promoting complex
           subunit 1 [Homo sapiens]
          Length = 679

 Score = 30.4 bits (67), Expect = 4.5
 Identities = 17/45 (37%), Positives = 22/45 (48%)

Query: 30  TRVSREGGVLKVHPTSTRFTFRTARQVPRLGVMLVGWGGNNGSTL 74
           TR++     L+      RF+FR +  V  L   LVGW  N G TL
Sbjct: 193 TRITVAPQKLQAEQEENRFSFRHSTSVSSLAERLVGWMTNVGFTL 237


>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
            sapiens]
          Length = 2602

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 7/70 (10%)

Query: 320  IGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKE----VSKSNVVDDMVQSNPVLYTPGE 375
            +GSG++   + S+    +  G    APL+ R       V   NVVD+   ++ V YTP +
Sbjct: 1431 LGSGVRARVLQSFTVDSSKAG---LAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQ 1487

Query: 376  EPDHCVVIKY 385
            E  + V +KY
Sbjct: 1488 EGPYMVSVKY 1497


>gi|46487911 zinc finger protein 406 isoform ZFAT-1 [Homo sapiens]
          Length = 1243

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 15/84 (17%)

Query: 241  LNDTAENLLRTI-ELGLE------------VSPSTLFAVASILEGCAFLNGSP--QNTLV 285
            L+ TA N+L+ I ELG E            ++P T+  V  + E     N +   Q T+ 
Sbjct: 1124 LDPTAVNILQQIIELGAETHDATALASVVAMAPGTVTVVKQVTEEEPSSNHTVMIQETVQ 1183

Query: 286  PGALELAWQHRVFVGGDDFKSGQT 309
              ++ELA QH + V  DD +  +T
Sbjct: 1184 QASVELAEQHHLVVSSDDVEGIET 1207


>gi|93102377 RRN3 RNA polymerase I transcription factor homolog
           [Homo sapiens]
          Length = 651

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 44/201 (21%), Positives = 83/201 (41%), Gaps = 17/201 (8%)

Query: 323 GLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVVDDMVQ-SNPVLYTPGEEPDHCV 381
           G  T  ++ Y     ND E L    Q    ++    +++ +++  + ++Y   +      
Sbjct: 54  GTVTEVLLKYKKGETNDFELLKN--QLLDPDIKDDQIINWLLEFRSSIMYLTKDFEQLIS 111

Query: 382 VIKYVPYVGDSKRALDEYTSEL-MLGGTNTLVLHNTCEDSLLAAPIMLDLALLTELCQRV 440
           +I  +P++  S+  ++EY + L  L    T+ L      S++A+  +    ++ E    V
Sbjct: 112 IILRLPWLNRSQTVVEEYLAFLGNLVSAQTVFLRPCL--SMIASHFVPPRVIIKEGDVDV 169

Query: 441 SFCTDMDPE-PQTF---HPVLSLLSFL------FKAPLVPPGSPVVNALFRQRSC-IENI 489
           S   D D   P  F   H  L +++        F  P++    P V    R   C + N+
Sbjct: 170 SDSDDEDDNLPANFDTCHRALQIIARYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNL 229

Query: 490 LRACVGLPPQNHMLLEHKMER 510
           LR  V  P   H +LE  +E+
Sbjct: 230 LRISVYFPTLRHEILELIIEK 250


>gi|4503313 diacylglycerol kinase epsilon [Homo sapiens]
          Length = 567

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 11/71 (15%)

Query: 106 GTVSLGLDA------EGQEVFVPFSAVLPMVAPNDLVFD-GWD---ISSLNLAEAMRRAK 155
           GTV   LDA      +GQE ++P  AVLP+   NDL    GW       + +A+ +R   
Sbjct: 281 GTVGWVLDAVDDMKIKGQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVM 340

Query: 156 VLDWGLQEQLW 166
             D G++   W
Sbjct: 341 EAD-GIKLDRW 350


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,396,095
Number of Sequences: 37866
Number of extensions: 1040924
Number of successful extensions: 2283
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2265
Number of HSP's gapped (non-prelim): 33
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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