Guide to the Human Genome
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Search of human proteins with 7705429

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705429 proteasome maturation protein [Homo sapiens]
         (141 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705429 proteasome maturation protein [Homo sapiens]               280   4e-76
gi|15529980 leucine rich repeat containing 46 [Homo sapiens]           33   0.10 
gi|17136148 ATPase, H+ transporting, lysosomal accessory protein...    31   0.30 
gi|116235485 delta-notch-like EGF repeat-containing transmembran...    29   1.5  
gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]              28   1.9  
gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]              28   1.9  
gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]              28   1.9  
gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]              28   1.9  
gi|208022687 GTPase regulator associated with the focal adhesion...    27   5.6  
gi|7662208 GTPase regulator associated with the focal adhesion k...    27   5.6  
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]            26   9.5  

>gi|7705429 proteasome maturation protein [Homo sapiens]
          Length = 141

 Score =  280 bits (715), Expect = 4e-76
 Identities = 141/141 (100%), Positives = 141/141 (100%)

Query: 1   MNARGLGSELKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQD 60
           MNARGLGSELKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQD
Sbjct: 1   MNARGLGSELKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQD 60

Query: 61  KMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETIGFEDILND 120
           KMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETIGFEDILND
Sbjct: 61  KMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETIGFEDILND 120

Query: 121 PSQSEVMGEPHLMVEYKLGLL 141
           PSQSEVMGEPHLMVEYKLGLL
Sbjct: 121 PSQSEVMGEPHLMVEYKLGLL 141


>gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
          Length = 321

 Score = 32.7 bits (73), Expect = 0.10
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 20 SASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQ-------LNQDKMNFSTLRNIQG 72
          SA GP E    + +     +N   P    ELSEK F        +  D+   +T+RN++G
Sbjct: 6  SAQGPEEGGVCITEALITKRNLTFPEDG-ELSEKMFHTLDELQTVRLDREGITTIRNLEG 64

Query: 73 LFAPLKLQMEFKAVQQVQRLPFLSS 97
          L     L ++   +QQ++ L  + S
Sbjct: 65 LQNLHSLYLQGNKIQQIENLACIPS 89


>gi|17136148 ATPase, H+ transporting, lysosomal accessory protein 1
           precursor [Homo sapiens]
          Length = 470

 Score = 31.2 bits (69), Expect = 0.30
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 59  QDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSL--DVLRGNDETIG 113
           Q+K+  S L         LKL     A+  + RLP+ +SS L    +VL GNDE IG
Sbjct: 149 QEKLGASPLHVDLATLRELKLNASLPALLLI-RLPYTASSGLMAPREVLTGNDEVIG 204


>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
          [Homo sapiens]
          Length = 737

 Score = 28.9 bits (63), Expect = 1.5
 Identities = 15/49 (30%), Positives = 20/49 (40%)

Query: 7  GSELKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNF 55
          GS L + +P   LSA GP  +      G    + E  P HP    E  +
Sbjct: 30 GSSLANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGY 78


>gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]
          Length = 410

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 35  FSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAP---LKLQMEFKAVQQVQR 91
           F  +K  ++ ++  E+++ N  L + +M F+     + +  P   L+   EF+   +V +
Sbjct: 207 FETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIK 266

Query: 92  LPFLSSSNLSLDVLRGNDETIGFEDI 117
              L  SNL    L  N +T  +EDI
Sbjct: 267 ETPLPPSNLPASPLMKNFDTSQWEDI 292


>gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 35  FSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAP---LKLQMEFKAVQQVQR 91
           F  +K  ++ ++  E+++ N  L + +M F+     + +  P   L+   EF+   +V +
Sbjct: 204 FETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIK 263

Query: 92  LPFLSSSNLSLDVLRGNDETIGFEDI 117
              L  SNL    L  N +T  +EDI
Sbjct: 264 ETPLPPSNLPASPLMKNFDTSQWEDI 289


>gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 35  FSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAP---LKLQMEFKAVQQVQR 91
           F  +K  ++ ++  E+++ N  L + +M F+     + +  P   L+   EF+   +V +
Sbjct: 204 FETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIK 263

Query: 92  LPFLSSSNLSLDVLRGNDETIGFEDI 117
              L  SNL    L  N +T  +EDI
Sbjct: 264 ETPLPPSNLPASPLMKNFDTSQWEDI 289


>gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 35  FSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAP---LKLQMEFKAVQQVQR 91
           F  +K  ++ ++  E+++ N  L + +M F+     + +  P   L+   EF+   +V +
Sbjct: 204 FETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIK 263

Query: 92  LPFLSSSNLSLDVLRGNDETIGFEDI 117
              L  SNL    L  N +T  +EDI
Sbjct: 264 ETPLPPSNLPASPLMKNFDTSQWEDI 289


>gi|208022687 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform b [Homo sapiens]
          Length = 759

 Score = 26.9 bits (58), Expect = 5.6
 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 58  NQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETI 112
           N  K N  T+ N+  +F P  L+ + + V  +  + F    N+ +++L  N E I
Sbjct: 516 NNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKF---QNIVIEILIENHEKI 567


>gi|7662208 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform a [Homo sapiens]
          Length = 814

 Score = 26.9 bits (58), Expect = 5.6
 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 58  NQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETI 112
           N  K N  T+ N+  +F P  L+ + + V  +  + F    N+ +++L  N E I
Sbjct: 516 NNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKF---QNIVIEILIENHEKI 567


>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
          Length = 786

 Score = 26.2 bits (56), Expect = 9.5
 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 58  NQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETI 112
           N  K N  T+ N+  +F P  ++ + + V  +  L F    N+ +++L  N E I
Sbjct: 522 NHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKF---QNIVVEILIENHEKI 573


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,860,752
Number of Sequences: 37866
Number of extensions: 182228
Number of successful extensions: 430
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 428
Number of HSP's gapped (non-prelim): 11
length of query: 141
length of database: 18,247,518
effective HSP length: 92
effective length of query: 49
effective length of database: 14,763,846
effective search space: 723428454
effective search space used: 723428454
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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